MGE detailed information
MGE type: Conjugative plasmid MGE length: 127790 bp
Accession: NZ_CP101198 Location: 1..127790 Organism: Escherichia coli strain EC21Z-151 Replicon: plasmid pEC21Z151-128K-NDM5
Accession: NZ_CP101198 Location: 1..127790 Organism: Escherichia coli strain EC21Z-151 Replicon: plasmid pEC21Z151-128K-NDM5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NML27_RS24320 (46) | 46..1077 | + | 1032 | WP_000907866.1 | plasmid replication initiator RepA | - |
| NML27_RS24325 (1775) | 1775..1990 | + | 216 | WP_000841013.1 | hypothetical protein | - |
| NML27_RS24330 (1987) | 1987..2979 | + | 993 | WP_001579760.1 | hypothetical protein | - |
| NML27_RS24335 (3038) | 3038..3655 | - | 618 | WP_000521604.1 | ProQ/FINO family protein | - |
| NML27_RS24340 (3850) | 3850..5406 | - | 1557 | WP_001579759.1 | AAA family ATPase | - |
| NML27_RS24345 (5671) | 5671..6261 | - | 591 | WP_000194568.1 | hypothetical protein | - |
| NML27_RS24350 (6261) | 6261..6518 | - | 258 | WP_000371888.1 | hypothetical protein | - |
| NML27_RS24355 (6847) | 6847..7950 | + | 1104 | WP_001127573.1 | nucleotide-binding protein | - |
| NML27_RS24360 (7980) | 7980..9140 | + | 1161 | WP_064148452.1 | DUF4238 domain-containing protein | - |
| NML27_RS24365 (9152) | 9152..9856 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| NML27_RS24370 (9910) | 9910..10014 | - | 105 | Protein_10 | recombinase family protein | - |
| NML27_RS24375 (10253) | 10253..11467 | + | 1215 | WP_001532073.1 | type II site-specific deoxyribonuclease | - |
| NML27_RS24380 (11501) | 11501..12934 | - | 1434 | WP_001288435.1 | DNA cytosine methyltransferase | - |
| NML27_RS24385 (13028) | 13028..13300 | + | 273 | Protein_13 | IS1 family transposase | - |
| NML27_RS24390 (13557) | 13557..14254 | + | 698 | WP_103215986.1 | IS1 family transposase IS1R | Transposase |
| NML27_RS24395 (14375) | 14375..15213 | - | 839 | Protein_15 | Streptomycin 3''-adenylyltransferase | ARG |
| NML27_RS24400 (15362) | 15362..16375 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| NML27_RS24405 (16578) | 16578..16928 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| NML27_RS24410 (17162) | 17162..17716 | + | 555 | Protein_18 | IS6-like element IS26 family transposase | - |
| NML27_RS24415 (17768) | 17768..18472 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| NML27_RS24420 (18538) | 18538..19896 | - | 1359 | Protein_20 | Tn3 family transposase TnpA_Tn3 | Transposase |
| NML27_RS24425 (20060) | 20060..20434 | + | 375 | Protein_21 | Tn3 family transposase TnpR_Tn3 | Transposase |
| NML27_RS24430 (20486) | 20486..21190 | - | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| NML27_RS24435 (21782) | 21782..22366 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| NML27_RS24440 (22366) | 22366..23604 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| NML27_RS24445 (23601) | 23601..24506 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| NML27_RS24450 (24628) | 24628..25332 | - | 705 | WP_001067855.1 | IS6 family transposase IS15DI | Transposase |
| NML27_RS24455 (25402) | 25402..25554 | + | 153 | Protein_27 | IS6 family transposase IS15DI | Transposase |
| NML27_RS24460 (25603) | 25603..26508 | - | 906 | Protein_28 | IS4 family transposase IS10R | Transposase |
| NML27_RS24465 (26651) | 26651..27511 | + | 861 | WP_000557454.1 | SPbeta prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| NML27_RS24470 (27524) | 27524..28066 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| NML27_RS24475 (28548) | 28548..28739 | - | 192 | WP_000951934.1 | hypothetical protein | - |
| NML27_RS24480 (28763) | 28763..28990 | + | 228 | WP_000248278.1 | hypothetical protein | - |
| NML27_RS24485 (29041) | 29041..30168 | + | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| NML27_RS24490 (30205) | 30205..30909 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| NML27_RS24495 (30964) | 30964..31830 | - | 867 | Protein_35 | IS91 family transposase ISAzo26 | Transposase |
| NML27_RS24500 (31975) | 31975..32472 | + | 498 | WP_001083725.1 | IS1595 family transposase ISSsu9 | ARG |
| NML27_RS24505 (32584) | 32584..32874 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| NML27_RS24510 (32880) | 32880..33718 | + | 839 | Protein_38 | Streptomycin 3''-adenylyltransferase | ARG |
| NML27_RS24515 (33835) | 33835..34182 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| NML27_RS24520 (34176) | 34176..35015 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| NML27_RS24525 (35420) | 35420..36961 | + | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| NML27_RS24530 (37274) | 37274..37648 | + | 375 | Protein_42 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| NML27_RS24535 (37748) | 37748..38305 | + | 558 | Protein_43 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| NML27_RS24540 (38316) | 38316..38954 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| NML27_RS24545 (38959) | 38959..39324 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| NML27_RS24550 (39328) | 39328..40140 | - | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| NML27_RS24555 (40241) | 40241..40534 | - | 294 | Protein_47 | IS30 family transposase ISAba125 | Transposase |
| NML27_RS24560 (40699) | 40699..41403 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| NML27_RS24565 (41597) | 41597..41947 | - | 351 | Protein_49 | 60 kDa chaperonin | VF |
| NML27_RS24570 (42010) | 42010..42558 | + | 549 | WP_014342204.1 | cation:proton antiporter | - |
| NML27_RS24575 (42639) | 42639..43394 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| NML27_RS24580 (43564) | 43564..44424 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| NML27_RS24585 (44607) | 44607..44798 | - | 192 | Protein_53 | helix-turn-helix domain-containing protein | - |
| NML27_RS24590 (44952) | 44952..45656 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| NML27_RS24595 (45712) | 45712..45822 | + | 111 | Protein_55 | korC | - |
| NML27_RS24600 (46341) | 46341..47474 | + | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| NML27_RS24605 (47494) | 47494..47778 | + | 285 | WP_000642771.1 | hypothetical protein | - |
| NML27_RS24610 (47949) | 47949..48596 | - | 648 | WP_000074712.1 | hypothetical protein | - |
| NML27_RS24615 (48584) | 48584..48919 | - | 336 | WP_000628093.1 | hypothetical protein | - |
| NML27_RS24620 (49099) | 49099..49680 | - | 582 | WP_000139427.1 | hypothetical protein | - |
| NML27_RS24625 (50250) | 50250..50600 | + | 351 | WP_000493380.1 | hypothetical protein | - |
| NML27_RS24630 (50670) | 50670..51278 | + | 609 | WP_063074920.1 | hypothetical protein | - |
| NML27_RS24635 (51346) | 51346..52128 | + | 783 | WP_001372173.1 | site-specific integrase | - |
| NML27_RS24640 (52266) | 52266..52541 | - | 276 | WP_000239529.1 | hypothetical protein | - |
| NML27_RS24645 (52535) | 52535..53179 | - | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| NML27_RS24650 (53408) | 53408..54379 | + | 972 | WP_001103690.1 | plasmid segregation protein ParM | - |
| NML27_RS24655 (54384) | 54384..54776 | + | 393 | WP_000340829.1 | plasmid partitioning/stability family protein | - |
| NML27_RS24660 (54781) | 54781..56052 | - | 1272 | WP_000457523.1 | Y-family DNA polymerase | - |
| NML27_RS24665 (56052) | 56052..56489 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| NML27_RS24670 (56486) | 56486..56734 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| NML27_RS24675 (57152) | 57152..58054 | + | 903 | WP_072748701.1 | DUF1281 domain-containing protein | - |
| NML27_RS24680 (58051) | 58051..58362 | + | 312 | WP_032072582.1 | hypothetical protein | - |
| NML27_RS24685 (58439) | 58439..59122 | + | 684 | WP_000086147.1 | DNA methylase | - |
| NML27_RS24690 (59123) | 59123..59344 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| NML27_RS24695 (59358) | 59358..59792 | + | 435 | WP_000274500.1 | DUF1380 family protein | - |
| NML27_RS24700 (59838) | 59838..60614 | + | 777 | WP_001005023.1 | hypothetical protein | - |
| NML27_RS24705 (61026) | 61026..61451 | + | 426 | WP_001579750.1 | antirestriction protein | - |
| NML27_RS24710 (61498) | 61498..61920 | + | 423 | WP_000271744.1 | DUF1380 family protein | - |
| NML27_RS24715 (61917) | 61917..62108 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| NML27_RS24720 (62179) | 62179..62493 | + | 315 | WP_001434357.1 | hypothetical protein | - |
| NML27_RS24725 (62877) | 62877..63404 | + | 528 | WP_001276107.1 | single-stranded DNA-binding protein | - |
| NML27_RS24730 (63462) | 63462..63695 | + | 234 | WP_000006020.1 | DUF905 domain-containing protein | - |
| NML27_RS24735 (63754) | 63754..65712 | + | 1959 | WP_001145485.1 | ParB/RepB/Spo0J family partition protein | - |
| NML27_RS24740 (65767) | 65767..66201 | + | 435 | WP_001387500.1 | conjugation system SOS inhibitor PsiB | - |
| NML27_RS24745 (66198) | 66198..66917 | + | 720 | WP_001276270.1 | plasmid SOS inhibition protein A | - |
| NML27_RS24750 (66914) | 66914..67510 | + | 597 | Protein_86 | hypothetical protein | - |
| NML27_RS24755 (67972) | 67972..68472 | + | 501 | WP_000117611.1 | antirestriction protein ArdA | - |
| NML27_RS24760 (69201) | 69201..69635 | + | 435 | WP_000218863.1 | hypothetical protein | - |
| NML27_RS24765 (69729) | 69729..69995 | + | 267 | WP_001247862.1 | hypothetical protein | - |
| NML27_RS24770 (70060) | 70060..70986 | + | 927 | WP_000038402.1 | ISNCY family transposase ISRor2 | VF |
| NML27_RS24775 (71009) | 71009..71206 | + | 198 | WP_001348086.1 | hypothetical protein | - |
| NML27_RS24780 (71237) | 71237..71488 | - | 252 | WP_000148285.1 | helix-turn-helix transcriptional regulator | - |
| NML27_RS24785 (72068) | 72068..72916 | + | 849 | WP_001077023.1 | DUF4942 domain-containing protein | - |
| NML27_RS24790 (73002) | 73002..73337 | - | 336 | WP_000157098.1 | hypothetical protein | - |
| NML27_RS24795 (73571) | 73571..73903 | + | 333 | WP_001283947.1 | IncI1-type relaxosome accessory protein NikA | - |
| NML27_RS24800 (73914) | 73914..76613 | + | 2700 | WP_001405892.1 | hypothetical protein | Relaxase |
| NML27_RS24805 (76650) | 76650..78941 | - | 2292 | WP_001289276.1 | F-type conjugative transfer protein TrbC | - |
| NML27_RS24810 (78934) | 78934..80004 | - | 1071 | WP_000151582.1 | IncI1-type conjugal transfer protein TrbB | - |
| NML27_RS24815 (80023) | 80023..81231 | - | 1209 | WP_000121273.1 | IncI1-type conjugal transfer protein TrbA | - |
| - (81411) | 81411..81473 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (81411) | 81411..81473 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (81411) | 81411..81473 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (81411) | 81411..81473 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| NML27_RS24820 (81523) | 81523..81675 | + | 153 | WP_001303307.1 | Hok/Gef family protein | Toxin Detail |
| NML27_RS24825 (81747) | 81747..81998 | - | 252 | WP_001291968.1 | hypothetical protein | - |
| - (82385) | 82385..82436 | - | 52 | NuclAT_1 | - | - |
| - (82385) | 82385..82436 | - | 52 | NuclAT_1 | - | - |
| - (82385) | 82385..82436 | - | 52 | NuclAT_1 | - | - |
| - (82385) | 82385..82436 | - | 52 | NuclAT_1 | - | - |
| NML27_RS24830 (82922) | 82922..83098 | - | 177 | WP_001054900.1 | hypothetical protein | - |
| NML27_RS24835 (83307) | 83307..83516 | - | 210 | WP_001140545.1 | hemolysin expression modulator Hha | - |
| NML27_RS24840 (83614) | 83614..84228 | - | 615 | WP_000578649.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| NML27_RS24845 (84304) | 84304..86472 | - | 2169 | WP_000698360.1 | IncI1-type conjugal transfer membrane protein TraY | - |
| NML27_RS24850 (86569) | 86569..87153 | - | 585 | WP_001579774.1 | IncI1-type conjugal transfer protein TraX | - |
| NML27_RS24855 (87182) | 87182..88384 | - | 1203 | WP_001189159.1 | IncI1-type conjugal transfer protein TraW | - |
| NML27_RS24860 (88351) | 88351..88965 | - | 615 | WP_000337394.1 | IncI1-type conjugal transfer protein TraV | - |
| NML27_RS24865 (88965) | 88965..92009 | - | 3045 | WP_001024752.1 | IncI1-type conjugal transfer protein TraU | - |
| NML27_RS24870 (92099) | 92099..92899 | - | 801 | WP_001164788.1 | IncI1-type conjugal transfer protein TraT | - |
| NML27_RS24875 (92883) | 92883..93071 | - | 189 | WP_001277255.1 | putative conjugal transfer protein TraS | - |
| NML27_RS24880 (93135) | 93135..93539 | - | 405 | WP_000086960.1 | IncI1-type conjugal transfer protein TraR | - |
| NML27_RS24885 (93590) | 93590..94117 | - | 528 | WP_001055569.1 | conjugal transfer protein TraQ | - |
| NML27_RS24890 (94117) | 94117..94821 | - | 705 | WP_000801920.1 | IncI1-type conjugal transfer protein TraP | - |
| NML27_RS24895 (94821) | 94821..96110 | - | 1290 | WP_063074922.1 | conjugal transfer protein TraO | - |
| NML27_RS24900 (96113) | 96113..97096 | - | 984 | WP_001191878.1 | hypothetical protein | VF |
| NML27_RS24905 (97107) | 97107..97799 | - | 693 | WP_000138552.1 | DotI/IcmL family type IV secretion protein | - |
| NML27_RS24910 (97796) | 97796..98143 | - | 348 | WP_001055900.1 | conjugal transfer protein | - |
| NML27_RS24915 (98161) | 98161..101928 | - | 3768 | WP_001579768.1 | DUF5710 domain-containing protein | - |
| NML27_RS24920 (102018) | 102018..102569 | - | 552 | WP_000014584.1 | Phospholipase D | VF |
| NML27_RS24925 (102584) | 102584..102874 | - | 291 | WP_001372180.1 | hypothetical protein | - |
| NML27_RS24930 (102871) | 102871..104019 | - | 1149 | WP_001024972.1 | putative protein YggR | VF |
| NML27_RS24935 (104016) | 104016..104834 | - | 819 | WP_000646097.1 | hypothetical protein | VF |
| NML27_RS24940 (104831) | 104831..105289 | - | 459 | WP_001079808.1 | hypothetical protein | VF |
| NML27_RS24945 (105684) | 105684..106268 | - | 585 | WP_000977522.1 | histidine phosphatase family protein | - |
| NML27_RS24950 (106328) | 106328..107530 | - | 1203 | WP_000976353.1 | conjugal transfer protein TraF | - |
| NML27_RS24955 (107616) | 107616..108440 | - | 825 | WP_001238929.1 | conjugal transfer protein TraE | - |
| NML27_RS24960 (108591) | 108591..109745 | - | 1155 | WP_001139958.1 | site-specific integrase | - |
| NML27_RS24965 (109744) | 109744..110097 | + | 354 | WP_001393368.1 | hypothetical protein | - |
| NML27_RS24970 (111266) | 111266..111514 | + | 249 | WP_001349157.1 | hypothetical protein | - |
| NML27_RS24975 (111511) | 111511..112803 | - | 1293 | WP_001417545.1 | hypothetical protein | VF |
| NML27_RS24980 (112803) | 112803..113459 | - | 657 | WP_001193553.1 | hypothetical protein | VF |
| NML27_RS24985 (113444) | 113444..114004 | - | 561 | WP_000014116.1 | hypothetical protein | VF |
| NML27_RS24990 (114014) | 114014..114628 | - | 615 | WP_254825277.1 | hypothetical protein | VF |
| NML27_RS24995 (114646) | 114646..115743 | - | 1098 | WP_001208805.1 | hypothetical protein | VF |
| NML27_RS25000 (115756) | 115756..117309 | - | 1554 | WP_000362202.1 | hypothetical protein | VF |
| NML27_RS25005 (117320) | 117320..117772 | - | 453 | WP_001247334.1 | hypothetical protein | VF |
| NML27_RS25010 (117759) | 117759..119054 | - | 1296 | WP_000752772.1 | hypothetical protein | VF |
| NML27_RS25015 (119047) | 119047..120729 | - | 1683 | WP_000748143.1 | hypothetical protein | VF |
| NML27_RS25020 (120743) | 120743..121180 | - | 438 | WP_000539807.1 | hypothetical protein | VF |
| NML27_RS25025 (121180) | 121180..122247 | - | 1068 | WP_001302629.1 | hypothetical protein | VF |
| NML27_RS25030 (122871) | 122871..123167 | - | 297 | WP_000494779.1 | hypothetical protein | - |
| NML27_RS25035 (123343) | 123343..123597 | - | 255 | WP_001136187.1 | PilI type IV pilus biogenesis protein | - |
| NML27_RS25040 (123759) | 123759..124310 | - | 552 | WP_000744644.1 | hypothetical protein | - |
| NML27_RS25045 (124483) | 124483..125166 | - | 684 | WP_000213859.1 | conjugal transfer protein TraC | - |
| NML27_RS25050 (125420) | 125420..125953 | - | 534 | WP_001372168.1 | transcription termination/antitermination NusG family protein | - |
| NML27_RS25055 (126395) | 126395..126682 | - | 288 | WP_000074855.1 | conjugal transfer protein TraA | - |
| NML27_RS25060 (126720) | 126720..126878 | - | 159 | Protein_148 | ash family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|