MGE detailed information

MGE type: Conjugative plasmid        MGE length: 150096 bp
Accession: NZ_CP099415        Location: 1..150096         Organism: Klebsiella pneumoniae strain 33367       Replicon: plasmid pSKLX33367_KPC2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NE847_RS28205 (1) 1..858 + 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
NE847_RS28210 (1797) 1797..2450 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
NE847_RS28215 (2543) 2543..2800 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
NE847_RS28220 (2733) 2733..3134 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
NE847_RS28225 (3383) 3383..3798 + 416 Protein_4 IS1 family transposase -
NE847_RS28230 (3834) 3834..4379 - 546 Protein_5 Tn3 family transposase TnpA_Tn3 Transposase
NE847_RS28235 (4445) 4445..5149 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NE847_RS28240 (5219) 5219..5410 + 192 Protein_7 IS1380 family transposase -
NE847_RS28245 (5660) 5660..6535 + 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
NE847_RS28250 (6570) 6570..7538 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
NE847_RS28255 (7595) 7595..8692 + 1098 Protein_10 TonB-dependent receptor -
NE847_RS28260 (8760) 8760..9236 - 477 Protein_11 PAS domain-containing protein -
NE847_RS28265 (9289) 9289..9993 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NE847_RS28270 (10058) 10058..10648 + 591 Protein_13 IS91 family transposase ISSbo1 Transposase
NE847_RS28275 (11104) 11104..11808 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NE847_RS28280 (11874) 11874..12392 + 519 WP_014839979.1 FidL-like protein -
NE847_RS28285 (12397) 12397..12813 - 417 WP_014839980.1 Glutathione transferase FosA ARG
NE847_RS28290 (13199) 13199..13903 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NE847_RS28295 (13954) 13954..14571 - 618 Protein_18 IS91 family transposase ISSbo1 Transposase
NE847_RS28300 (14581) 14581..14769 - 189 WP_000957857.1 hypothetical protein -
NE847_RS28305 (14861) 14861..15397 + 537 WP_064441864.1 Tn3 family transposase TnpR_Tn3 Transposase
NE847_RS28310 (15580) 15580..16440 + 861 WP_000027057.1 Beta-lactamase TEM ARG
NE847_RS28315 (16610) 16610..17365 + 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
NE847_RS28320 (17446) 17446..17760 - 315 Protein_23 hypothetical protein -
NE847_RS28325 (17815) 17815..18519 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
NE847_RS28330 (20099) 20099..20333 + 235 Protein_25 type II toxin-antitoxin system RelE/ParE family toxin -
NE847_RS28335 (20461) 20461..20742 + 282 WP_001333089.1 hypothetical protein -
NE847_RS28340 (20865) 20865..21215 - 351 WP_000361389.1 plasmid partitioning/stability family protein -
NE847_RS28345 (21218) 21218..22180 - 963 WP_000959884.1 plasmid segregation protein ParM -
NE847_RS28350 (22327) 22327..22620 + 294 WP_032146011.1 hypothetical protein -
NE847_RS28355 (22697) 22697..23380 + 684 WP_000085883.1 DNA methylase -
NE847_RS28360 (23381) 23381..23602 + 222 WP_001104881.1 hypothetical protein -
NE847_RS28365 (23616) 23616..24050 + 435 WP_000274503.1 DUF1380 family protein -
NE847_RS28370 (24101) 24101..24877 + 777 WP_001383963.1 hypothetical protein -
NE847_RS28375 (25295) 25295..25720 + 426 WP_001198928.1 antirestriction protein -
NE847_RS28380 (25767) 25767..26189 + 423 WP_000271762.1 DUF1380 family protein -
NE847_RS28385 (26186) 26186..26377 + 192 WP_001027493.1 hypothetical protein -
NE847_RS28390 (26691) 26691..28358 - 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
NE847_RS28395 (29087) 29087..29241 - 155 Protein_38 hypothetical protein -
NE847_RS28400 (29758) 29758..29988 + 231 WP_000218642.1 hypothetical protein -
NE847_RS28405 (30040) 30040..31401 + 1362 WP_000170695.1 DUF3560 domain-containing protein -
NE847_RS28410 (31448) 31448..32011 + 564 WP_015059007.1 class I SAM-dependent methyltransferase -
NE847_RS28415 (32097) 32097..32552 - 456 Protein_42 hypothetical protein -
NE847_RS28420 (32854) 32854..33381 + 528 WP_000290834.1 single-stranded DNA-binding protein -
NE847_RS28425 (33439) 33439..33672 + 234 WP_000006003.1 DUF905 family protein -
NE847_RS28430 (33733) 33733..35756 + 2024 Protein_45 ParB/RepB/Spo0J family partition protein -
NE847_RS28435 (35825) 35825..36259 + 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
NE847_RS28440 (36256) 36256..36975 + 720 WP_001276217.1 plasmid SOS inhibition protein A -
- (36987) 36987..37211 + 225 NuclAT_0 - Antitoxin Detail
- (36987) 36987..37211 + 225 NuclAT_0 - Antitoxin Detail
- (36987) 36987..37211 + 225 NuclAT_0 - Antitoxin Detail
- (36987) 36987..37211 + 225 NuclAT_0 - Antitoxin Detail
NE847_RS28445 (37197) 37197..37346 + 150 Protein_48 plasmid maintenance protein Mok -
NE847_RS28450 (37288) 37288..37413 + 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
NE847_RS28455 (37732) 37732..38028 - 297 Protein_50 hypothetical protein -
NE847_RS28460 (38328) 38328..38624 + 297 WP_001272251.1 hypothetical protein -
NE847_RS28465 (38735) 38735..39556 + 822 WP_001234445.1 DUF932 domain-containing protein -
NE847_RS28470 (39853) 39853..40500 - 648 WP_015059008.1 hypothetical protein VF
NE847_RS28475 (40777) 40777..41160 + 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
NE847_RS28480 (41351) 41351..42037 + 687 WP_015059009.1 PAS domain-containing protein -
NE847_RS28485 (42131) 42131..42358 + 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
NE847_RS28490 (42392) 42392..42757 + 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
NE847_RS28495 (42772) 42772..43083 + 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
NE847_RS28500 (43105) 43105..43671 + 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
NE847_RS28505 (43658) 43658..44386 + 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
NE847_RS28510 (44386) 44386..45813 + 1428 WP_032297072.1 F-type conjugal transfer pilus assembly protein TraB -
NE847_RS28515 (45803) 45803..46393 + 591 WP_000002778.1 conjugal transfer pilus-stabilizing protein TraP -
NE847_RS28520 (46380) 46380..46577 + 198 WP_001324648.1 conjugal transfer protein TrbD -
NE847_RS28525 (46589) 46589..46840 + 252 WP_001038341.1 conjugal transfer protein TrbG -
NE847_RS28530 (46837) 46837..47352 + 516 WP_062955122.1 type IV conjugative transfer system lipoprotein TraV -
NE847_RS28535 (47487) 47487..47708 + 222 WP_001278692.1 conjugal transfer protein TraR -
NE847_RS28540 (47868) 47868..50495 + 2628 WP_015059012.1 type IV secretion system protein TraC -
NE847_RS28545 (50492) 50492..50878 + 387 WP_015059013.1 type-F conjugative transfer system protein TrbI -
NE847_RS28550 (50875) 50875..51507 + 633 WP_001203735.1 type-F conjugative transfer system protein TraW -
NE847_RS28555 (51504) 51504..52496 + 993 WP_000830838.1 conjugal transfer pilus assembly protein TraU -
NE847_RS28560 (52523) 52523..52831 + 309 WP_000412447.1 hypothetical protein -
NE847_RS28565 (52894) 52894..53415 + 522 WP_015059014.1 hypothetical protein -
NE847_RS28570 (53442) 53442..54080 + 639 WP_000087532.1 type-F conjugative transfer system pilin assembly protein TrbC -
NE847_RS28575 (54077) 54077..54448 + 372 WP_000056336.1 hypothetical protein -
NE847_RS28580 (54474) 54474..54896 + 423 WP_001229309.1 HNH endonuclease signature motif containing protein -
NE847_RS28585 (54893) 54893..56743 + 1851 WP_015059015.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
NE847_RS28590 (56770) 56770..57027 + 258 WP_053913405.1 conjugal transfer protein TrbE -
NE847_RS28595 (57014) 57014..57763 + 750 WP_072354014.1 type-F conjugative transfer system pilin assembly protein TraF -
NE847_RS28600 (57924) 57924..58160 + 237 WP_000270010.1 type-F conjugative transfer system pilin chaperone TraQ -
NE847_RS28605 (58147) 58147..58692 + 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
NE847_RS28610 (58682) 58682..58996 + 315 WP_001384255.1 P-type conjugative transfer protein TrbJ -
NE847_RS28615 (58950) 58950..59342 + 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
NE847_RS28620 (59329) 59329..60702 + 1374 WP_000944325.1 conjugal transfer pilus assembly protein TraH -
NE847_RS28625 (60699) 60699..63515 + 2817 WP_015059018.1 conjugal transfer mating-pair stabilization protein TraG -
NE847_RS28630 (63548) 63548..64069 + 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
NE847_RS28635 (64094) 64094..64825 + 732 WP_021559024.1 conjugal transfer complement resistance protein TraT -
NE847_RS28640 (65028) 65028..65765 + 738 WP_015059020.1 hypothetical protein -
NE847_RS28645 (65816) 65816..68032 + 2217 WP_059274178.1 type IV conjugative transfer system coupling protein TraD -
NE847_RS28650 (68032) 68032..73167 + 5136 WP_071177725.1 Multifunctional conjugation protein TraI Relaxase
NE847_RS28655 (73201) 73201..73905 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NE847_RS28660 (73971) 73971..74255 + 285 Protein_91 PAS domain-containing protein -
NE847_RS28665 (74319) 74319..75023 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NE847_RS28670 (75077) 75077..75400 - 324 Protein_93 class II aldolase/adducin family protein -
NE847_RS28675 (75393) 75393..76645 - 1253 Protein_94 four-carbon acid sugar kinase family protein -
NE847_RS28680 (76657) 76657..77559 - 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
NE847_RS28685 (77821) 77821..78582 + 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
NE847_RS28690 (78603) 78603..79463 - 861 WP_002904004.1 Beta-lactamase SHV-2 ARG
NE847_RS28695 (79600) 79600..79668 + 69 Protein_98 IS6 family transposase -
NE847_RS28700 (79704) 79704..82670 - 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
NE847_RS28705 (82674) 82674..83234 - 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
NE847_RS28710 (83626) 83626..84243 + 618 Protein_101 replication protein -
NE847_RS28715 (84777) 84777..85055 + 279 WP_013213990.1 hypothetical protein -
NE847_RS28720 (85166) 85166..85591 + 426 WP_013213989.1 antirestriction protein -
NE847_RS28725 (85719) 85719..85874 + 156 WP_013213988.1 hypothetical protein -
NE847_RS28730 (85920) 85920..86216 + 297 WP_013213987.1 transcriptional regulator -
NE847_RS28735 (86320) 86320..87201 + 882 Protein_106 IS1182 family transposase ISKpn6 Transposase
NE847_RS28740 (87451) 87451..88332 - 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
NE847_RS28745 (88608) 88608..89588 - 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
NE847_RS28750 (89711) 89711..90172 - 462 Protein_109 Tn3 family transposase TnpR_Tn3 Transposase
NE847_RS28755 (90224) 90224..90928 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NE847_RS28760 (90993) 90993..92165 - 1173 Protein_111 transposase -
NE847_RS28765 (92240) 92240..92908 - 669 WP_001300294.1 putative signaling protein VF
NE847_RS28770 (92944) 92944..93180 - 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
NE847_RS28775 (93177) 93177..93539 - 363 WP_001277456.1 mercury resistance co-regulator MerD -
NE847_RS28780 (93557) 93557..95251 - 1695 WP_000105636.1 mercury(II) reductase -
NE847_RS28785 (95303) 95303..95725 - 423 WP_001340589.1 organomercurial transporter MerC -
NE847_RS28790 (95761) 95761..96036 - 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
NE847_RS28795 (96050) 96050..96400 - 351 WP_001294663.1 mercuric transport protein MerT -
NE847_RS28800 (96472) 96472..96906 + 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
NE847_RS28805 (96985) 96985..97989 + 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
NE847_RS28810 (98269) 98269..98541 - 273 Protein_121 IS5 family transposase ISPan1 Transposase
NE847_RS28820 (99523) 99523..100545 - 1023 WP_000361404.1 helicase UvrD -
NE847_RS28825 (100530) 100530..102092 - 1563 WP_004206609.1 AAA family ATPase -
NE847_RS28830 (102166) 102166..102582 - 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
NE847_RS28835 (102579) 102579..102809 - 231 WP_001261282.1 type II toxin-antitoxin system VapB family antitoxin -
NE847_RS28840 (102766) 102766..103227 + 462 WP_014343465.1 hypothetical protein -
NE847_RS28845 (103388) 103388..104332 + 945 WP_011977810.1 hypothetical protein -
NE847_RS28850 (104369) 104369..104761 + 393 WP_011977811.1 hypothetical protein -
NE847_RS28855 (104819) 104819..105340 + 522 WP_013214008.1 hypothetical protein -
NE847_RS28860 (105386) 105386..105589 + 204 WP_011977813.1 hypothetical protein -
NE847_RS28865 (105619) 105619..106623 + 1005 WP_011977814.1 hypothetical protein -
NE847_RS28870 (106807) 106807..107586 + 780 WP_013214009.1 site-specific integrase -
NE847_RS28875 (107632) 107632..107889 - 258 WP_013214010.1 hypothetical protein -
NE847_RS28880 (108018) 108018..108131 - 114 WP_014343462.1 hypothetical protein -
NE847_RS28885 (108667) 108667..109533 + 867 WP_004118283.1 replication initiation protein -
NE847_RS28890 (110643) 110643..111848 + 1206 WP_011977818.1 AAA family ATPase -
NE847_RS28895 (111848) 111848..112822 + 975 WP_011977819.1 ParB family protein -
NE847_RS28900 (112904) 112904..114175 - 1272 WP_013214011.1 Y-family DNA polymerase -
NE847_RS28905 (114175) 114175..114606 - 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
NE847_RS28910 (115013) 115013..116500 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
NE847_RS28915 (116749) 116749..117720 + 972 WP_004152353.1 plasmid segregation protein ParM -
NE847_RS28920 (117723) 117723..118394 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
NE847_RS28925 (118457) 118457..118687 + 231 WP_001568040.1 hypothetical protein -
NE847_RS28930 (118883) 118883..119052 + 170 Protein_145 hypothetical protein -
NE847_RS28935 (119124) 119124..119825 + 702 WP_001568041.1 DNA methylase -
NE847_RS28940 (119825) 119825..120046 + 222 WP_001568042.1 hypothetical protein -
NE847_RS28945 (120056) 120056..120475 + 420 WP_001568043.1 DUF1380 domain-containing protein -
NE847_RS28950 (120529) 120529..121296 + 768 WP_013214013.1 hypothetical protein -
NE847_RS28955 (121977) 121977..122405 + 429 WP_001568045.1 antirestriction protein -
NE847_RS28960 (122448) 122448..122954 + 507 WP_013214014.1 antirestriction protein ArdA -
NE847_RS28965 (122997) 122997..123188 + 192 WP_001568047.1 hypothetical protein -
NE847_RS28970 (123376) 123376..123630 + 255 WP_011977779.1 DNA polymerase III subunit theta -
NE847_RS28975 (123665) 123665..123985 + 321 WP_001568049.1 hypothetical protein -
NE847_RS28980 (124665) 124665..124892 + 228 WP_001568050.1 hypothetical protein -
NE847_RS28985 (124984) 124984..125214 + 231 WP_001568051.1 hypothetical protein -
NE847_RS28990 (125266) 125266..126621 + 1356 WP_014343515.1 DUF3560 domain-containing protein -
NE847_RS28995 (126669) 126669..127232 + 564 WP_014343514.1 methyltransferase -
NE847_RS29000 (128065) 128065..128607 + 543 WP_014343512.1 single-stranded DNA-binding protein -
NE847_RS29005 (128656) 128656..128904 + 249 WP_001568055.1 DUF905 domain-containing protein -
NE847_RS29010 (128974) 128974..131031 + 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
NE847_RS29015 (131076) 131076..131507 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
NE847_RS29020 (131504) 131504..132232 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
NE847_RS29025 (132229) 132229..132555 + 327 WP_013023807.1 hypothetical protein -
NE847_RS29030 (132611) 132611..132985 + 375 WP_014343510.1 hypothetical protein -
NE847_RS29035 (133169) 133169..134242 - 1074 WP_013609528.1 IS481 family transposase ISKpn28 Transposase
NE847_RS29040 (134356) 134356..134472 + 117 WP_055313929.1 type I toxin-antitoxin system Hok family toxin -
NE847_RS29045 (135165) 135165..135437 + 273 WP_040245921.1 hypothetical protein -
NE847_RS29050 (135434) 135434..135784 + 351 WP_040245917.1 hypothetical protein -
NE847_RS29055 (135799) 135799..136116 + 318 WP_014343505.1 hypothetical protein -
NE847_RS29060 (136957) 136957..137313 + 357 WP_014343501.1 hypothetical protein -
NE847_RS29065 (137374) 137374..137586 + 213 WP_014343500.1 hypothetical protein -
NE847_RS29070 (137597) 137597..137821 + 225 WP_014343499.1 hypothetical protein -
NE847_RS29075 (137902) 137902..138222 + 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
NE847_RS29080 (138212) 138212..138490 + 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
NE847_RS29085 (138494) 138494..138598 + 105 Protein_176 transcriptional regulator -
NE847_RS29090 (139427) 139427..140248 + 822 WP_004152492.1 DUF932 domain-containing protein -
NE847_RS29095 (140281) 140281..140610 + 330 WP_013214015.1 DUF5983 family protein -
NE847_RS29100 (140643) 140643..141128 - 486 WP_014343495.1 hypothetical protein VF
NE847_RS29105 (141519) 141519..141935 + 417 WP_014343494.1 conjugal transfer relaxosome DNA-binding protein TraM -
NE847_RS29110 (142135) 142135..142872 + 738 WP_154244330.1 conjugal transfer protein TrbJ -
NE847_RS29115 (142987) 142987..143193 + 207 WP_171773970.1 TraY domain-containing protein -
NE847_RS29120 (143255) 143255..143623 + 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
NE847_RS29125 (143637) 143637..143942 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
NE847_RS29130 (143962) 143962..144327 + 366 Protein_185 type IV conjugative transfer system protein TraE -
NE847_RS29135 (144382) 144382..144726 - 345 Protein_186 IS6 family transposase IS26 Transposase
NE847_RS29140 (144778) 144778..145482 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
NE847_RS29145 (145507) 145507..145707 + 201 WP_072354025.1 hypothetical protein -
NE847_RS29150 (145727) 145727..146473 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
NE847_RS29155 (146528) 146528..147088 + 561 WP_000139328.1 fertility inhibition protein FinO -
NE847_RS29160 (147220) 147220..147420 + 201 WP_015059022.1 hypothetical protein -
NE847_RS29165 (147806) 147806..148405 + 600 WP_032083981.1 PIN domain-containing protein -
NE847_RS29170 (148467) 148467..148799 + 333 WP_152916585.1 hypothetical protein -
- (149000) 149000..149059 - 60 NuclAT_1 - Antitoxin Detail
- (149000) 149000..149059 - 60 NuclAT_1 - Antitoxin Detail
- (149000) 149000..149059 - 60 NuclAT_1 - Antitoxin Detail
- (149000) 149000..149059 - 60 NuclAT_1 - Antitoxin Detail
NE847_RS29175 (149104) 149104..149253 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
NE847_RS29180 (149537) 149537..149785 + 249 WP_000083837.1 replication regulatory protein RepA -
NE847_RS29185 (149900) 149900..150084 + 185 Protein_196 protein CopA/IncA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance