MGE detailed information
MGE type: Mobilizable plasmid MGE length: 104161 bp
Accession: NZ_CP097182 Location: 1..104161 Organism: Escherichia coli strain SH21PTE31 Replicon: plasmid pYUSHP31-1
Accession: NZ_CP097182 Location: 1..104161 Organism: Escherichia coli strain SH21PTE31 Replicon: plasmid pYUSHP31-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M4R35_RS22915 | 1..1011 | + | 1011 | WP_000200070.1 | RepB family plasmid replication initiator protein | - |
| M4R35_RS22920 | 1205..2173 | + | 969 | WP_077816224.1 | IS5 family transposase IS903B | Transposase |
| M4R35_RS22925 | 2340..2630 | - | 291 | WP_001471781.1 | hypothetical protein | - |
| M4R35_RS22930 | 3341..3676 | + | 336 | WP_001039462.1 | plasmid stabilization protein StbA | - |
| M4R35_RS22935 | 3685..3876 | + | 192 | WP_001515192.1 | hypothetical protein | - |
| M4R35_RS22940 | 3887..4470 | - | 584 | Protein_5 | IS1 family transposase IS1X4 | Transposase |
| M4R35_RS22945 | 5004..5759 | + | 756 | WP_000807690.1 | replication initiation protein RepE | - |
| M4R35_RS22950 | 6028..6373 | + | 346 | Protein_7 | IS1 family transposase IS1X4 | Transposase |
| M4R35_RS22955 | 6884..7024 | + | 141 | WP_160784086.1 | hypothetical protein | - |
| M4R35_RS22960 | 7119..7823 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M4R35_RS22965 | 9012..9569 | - | 558 | WP_023281049.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| M4R35_RS22970 | 9702..9854 | - | 153 | WP_165405807.1 | hypothetical protein | - |
| M4R35_RS22975 | 9932..10636 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M4R35_RS22980 | 10690..11475 | + | 786 | Protein_13 | Tn3 family transposase TnpA_Tn3 | Transposase |
| M4R35_RS22985 | 11508..11942 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| M4R35_RS22990 | 12014..12364 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| M4R35_RS22995 | 12378..12653 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| M4R35_RS23000 | 12689..13111 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| M4R35_RS23005 | 13163..14857 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| M4R35_RS23010 | 14875..15066 | + | 192 | Protein_19 | mercuric resistance transcriptional repressor protein MerD | - |
| M4R35_RS23015 | 15130..15834 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M4R35_RS23020 | 15962..17191 | + | 1230 | WP_032492336.1 | hypothetical protein | ARG |
| M4R35_RS23025 | 17337..18200 | + | 864 | WP_054377175.1 | SDR family oxidoreductase | - |
| M4R35_RS23030 | 18238..18483 | + | 246 | WP_001354008.1 | GrpB family protein | - |
| M4R35_RS23035 | 18952..19743 | + | 792 | WP_000034420.1 | Dihydropteroate synthase | ARG |
| M4R35_RS23040 | 19746..20021 | - | 276 | WP_109023896.1 | hypothetical protein | - |
| M4R35_RS23045 | 20044..20676 | + | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| M4R35_RS23050 | 20923..21048 | - | 126 | Protein_27 | quaternary ammonium compound efflux SMR transporter QacL | - |
| M4R35_RS23055 | 21101..21805 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M4R35_RS23060 | 21951..22964 | - | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| M4R35_RS23065 | 23120..23593 | + | 474 | WP_001317507.1 | Dihydrofolate reductase type 1 | ARG |
| M4R35_RS23070 | 23777..23878 | + | 102 | Protein_31 | SMR family transporter | - |
| M4R35_RS23075 | 23922..24626 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M4R35_RS23080 | 24691..25536 | + | 846 | Protein_33 | IS91 family transposase ISVsa3 | Transposase |
| M4R35_RS23085 | 25764..25901 | - | 138 | WP_164538590.1 | hypothetical protein | - |
| M4R35_RS23090 | 26318..27163 | + | 846 | WP_164538741.1 | macrolide hydrolase EstT | - |
| M4R35_RS23095 | 27153..28310 | + | 1158 | WP_094309310.1 | Flavin-dependent monooxygenase | ARG |
| M4R35_RS23100 | 28649..30142 | + | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| M4R35_RS23105 | 30504..32117 | + | 1614 | WP_136655509.1 | ATP-binding cassette domain-containing protein | - |
| M4R35_RS23110 | 32165..32794 | - | 630 | WP_136655510.1 | Chloramphenicol acetyltransferase | VF |
| M4R35_RS23115 | 33023..33472 | + | 450 | WP_166488538.1 | MarR family transcriptional regulator | - |
| M4R35_RS23120 | 33486..34850 | + | 1365 | Protein_41 | IS91 family transposase ISVsa3 | Transposase |
| M4R35_RS23125 | 34881..35765 | + | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| M4R35_RS23130 | 35982..37196 | + | 1215 | WP_034167813.1 | Inner membrane transport protein YdhC | ARG |
| M4R35_RS23135 | 37224..37529 | + | 306 | WP_001255015.1 | HTH-type transcriptional regulator HdfR | VF |
| M4R35_RS23140 | 37641..38294 | + | 654 | Protein_45 | IS91 family transposase ISPps1 | Transposase |
| M4R35_RS23145 | 38348..39052 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M4R35_RS23150 | 39118..39618 | + | 501 | Protein_47 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M4R35_RS23155 | 39676..39918 | + | 243 | WP_000844627.1 | transposase | - |
| M4R35_RS23160 | 39950..40600 | - | 651 | WP_001493764.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| M4R35_RS23165 | 40706..41905 | + | 1200 | WP_001493765.1 | tetracycline efflux MFS transporter Tet(A) | - |
| M4R35_RS23170 | 41937..42821 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| M4R35_RS23175 | 42959..43351 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| M4R35_RS23180 | 43355..44116 | + | 762 | Protein_53 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M4R35_RS23185 | 44152..47157 | - | 3006 | WP_001531602.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| M4R35_RS23190 | 47321..47878 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| M4R35_RS23195 | 48061..48921 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| M4R35_RS23200 | 49032..49526 | - | 495 | WP_077141251.1 | IS91 family transposase ISAzo26 | Transposase |
| M4R35_RS23205 | 49929..50561 | - | 633 | WP_020802982.1 | IS256 family transposase IS406 | Transposase |
| M4R35_RS23210 | 50584..50814 | + | 231 | WP_136655701.1 | hypothetical protein | - |
| M4R35_RS23215 | 50822..50989 | - | 168 | WP_000336323.1 | cysteine-rich KTR domain-containing protein | - |
| M4R35_RS23220 | 51108..53027 | - | 1920 | WP_025989258.1 | tetracycline resistance ribosomal protection protein Tet(M) | VF |
| M4R35_RS23225 | 53043..53159 | - | 117 | WP_001814923.1 | tetracycline resistance determinant leader peptide | - |
| M4R35_RS23230 | 53404..53871 | - | 468 | Protein_63 | conjugal transfer protein | - |
| M4R35_RS23235 | 53925..54458 | - | 534 | Protein_64 | IS6 family transposase IS26 | Transposase |
| M4R35_RS23240 | 54512..55216 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| M4R35_RS23245 | 55377..56033 | - | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| M4R35_RS23250 | 56424..56681 | - | 258 | Protein_67 | ISKra4 family transposase ISKpn19 | Transposase |
| M4R35_RS23255 | 56735..57439 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| M4R35_RS23260 | 57706..59142 | + | 1437 | WP_000105383.1 | glutathione synthase | - |
| M4R35_RS23265 | 59477..60174 | + | 698 | WP_225528490.1 | IS1-like element IS1A family transposase | - |
| M4R35_RS23270 | 60199..60633 | - | 435 | WP_053273090.1 | hypothetical protein | - |
| M4R35_RS23275 | 60614..60697 | + | 84 | WP_000565612.1 | damage-inducible type I toxin DinQ | - |
| M4R35_RS23280 | 60852..61496 | - | 645 | WP_000203396.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| M4R35_RS23285 | 61877..62539 | + | 663 | WP_000516402.1 | division plane positioning ATPase MipZ | - |
| M4R35_RS23290 | 62637..62918 | + | 282 | WP_001185482.1 | hypothetical protein | - |
| M4R35_RS23295 | 62943..63920 | + | 978 | WP_024245156.1 | hypothetical protein | - |
| M4R35_RS23300 | 63917..64273 | - | 357 | WP_000456533.1 | DNA distortion polypeptide 3 | - |
| M4R35_RS23305 | 64410..64856 | - | 447 | Protein_78 | hypothetical protein | - |
| M4R35_RS23310 | 64896..65732 | - | 837 | WP_001050931.1 | RepB family plasmid replication initiator protein | - |
| M4R35_RS23315 | 66966..67217 | + | 252 | WP_000121743.1 | plasmid stabilization protein | Antitoxin Detail |
| M4R35_RS23320 | 67207..67488 | + | 282 | WP_000220560.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| M4R35_RS23325 | 67563..68260 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| M4R35_RS23330 | 68406..68663 | + | 258 | WP_105278499.1 | hypothetical protein | - |
| M4R35_RS23335 | 68700..69668 | - | 969 | WP_077783444.1 | IS5 family transposase IS903B | Transposase |
| M4R35_RS23340 | 69688..69978 | + | 291 | WP_073503549.1 | peptidoglycan DD-metalloendopeptidase family protein | - |
| M4R35_RS23345 | 70012..70209 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| M4R35_RS23350 | 70250..72727 | - | 2478 | WP_001398208.1 | Ag(+)-translocating P-type ATPase SilP | - |
| M4R35_RS23355 | 72825..73265 | - | 441 | WP_000758229.1 | DUF411 domain-containing protein | - |
| M4R35_RS23360 | 73352..76498 | - | 3147 | WP_020219104.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| M4R35_RS23365 | 76509..77801 | - | 1293 | WP_001381488.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| M4R35_RS23370 | 77915..78268 | - | 354 | WP_001246155.1 | cation efflux system protein CusF | - |
| M4R35_RS23375 | 78296..79681 | - | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| M4R35_RS23380 | 79871..80551 | + | 681 | WP_000697969.1 | Transcriptional regulatory protein CusR | VF |
| M4R35_RS23385 | 80544..82019 | + | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| M4R35_RS23390 | 82270..82701 | + | 432 | WP_000790483.1 | silver-binding protein SilE | - |
| M4R35_RS23395 | 82845..83195 | + | 351 | WP_000694953.1 | DUF305 domain-containing protein | - |
| M4R35_RS23400 | 83583..84491 | - | 909 | Protein_97 | HNH endonuclease | - |
| M4R35_RS23405 | 84963..86191 | + | 1229 | WP_089541817.1 | IS3 family transposase IS2 | Transposase |
| M4R35_RS23410 | 86464..87438 | + | 975 | WP_001148756.1 | sensor domain-containing diguanylate cyclase | - |
| M4R35_RS23415 | 88368..89039 | + | 672 | WP_000796235.1 | hypothetical protein | - |
| M4R35_RS23420 | 89059..89847 | + | 789 | WP_022631000.1 | site-specific integrase | - |
| M4R35_RS23425 | 89905..90096 | - | 192 | WP_001326966.1 | hypothetical protein | - |
| M4R35_RS23430 | 90141..91038 | - | 898 | Protein_103 | IS3 family transposase ISEhe3 | Transposase |
| M4R35_RS23435 | 91047..92198 | - | 1152 | WP_001254932.1 | IS30 family transposase IS30D | Transposase |
| M4R35_RS23440 | 92280..92429 | - | 150 | Protein_105 | IS3 family transposase ISEhe3 | Transposase |
| M4R35_RS23445 | 92576..92857 | + | 282 | WP_000639434.1 | hypothetical protein | - |
| M4R35_RS23455 | 93765..95090 | + | 1326 | WP_021512928.1 | reactive chlorine resistance oxidoreductase RclA | - |
| M4R35_RS23460 | 95297..95994 | + | 698 | WP_225902390.1 | IS1-like element IS1B family transposase | - |
| M4R35_RS23465 | 96024..96371 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| M4R35_RS23470 | 96420..97957 | + | 1538 | Protein_111 | IS66 family transposase ISEc22 | Transposase |
| M4R35_RS23475 | 99271..99968 | + | 698 | WP_236919600.1 | IS1-like element IS1SD family transposase | - |
| M4R35_RS23480 | 99987..100832 | + | 846 | Protein_113 | IS3 family transposase IS911 | Transposase |
| M4R35_RS23485 | 101284..102255 | - | 972 | WP_000817038.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| M4R35_RS23490 | 102255..103421 | - | 1167 | WP_000523812.1 | hypothetical protein | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|