MGE detailed information
MGE type: Conjugative plasmid MGE length: 140101 bp
Accession: NZ_CP096589 Location: 1..140101 Organism: Escherichia coli strain EC6622 Replicon: plasmid pEC6622-2
Accession: NZ_CP096589 Location: 1..140101 Organism: Escherichia coli strain EC6622 Replicon: plasmid pEC6622-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| M1B75_RS24520 (376) | 376..663 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| M1B75_RS24525 (688) | 688..894 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| M1B75_RS24530 (964) | 964..1137 | + | 174 | Protein_3 | hypothetical protein | - |
| M1B75_RS24535 (1135) | 1135..1365 | - | 231 | WP_071587244.1 | hypothetical protein | - |
| M1B75_RS24540 (1585) | 1585..1710 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| M1B75_RS24545 (1652) | 1652..1801 | - | 150 | Protein_6 | plasmid maintenance protein Mok | - |
| - (1787) | 1787..2011 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (1787) | 1787..2011 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (1787) | 1787..2011 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (1787) | 1787..2011 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| M1B75_RS24550 (1823) | 1823..2011 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| M1B75_RS24555 (1980) | 1980..2742 | - | 763 | Protein_8 | plasmid SOS inhibition protein A | - |
| M1B75_RS24560 (2739) | 2739..3173 | - | 435 | WP_000845901.1 | conjugation system SOS inhibitor PsiB | - |
| M1B75_RS24565 (3228) | 3228..5186 | - | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| M1B75_RS24570 (5245) | 5245..5478 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| M1B75_RS24575 (5534) | 5534..6061 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| M1B75_RS24580 (6534) | 6534..6818 | - | 285 | WP_124767219.1 | hypothetical protein | - |
| M1B75_RS24585 (6704) | 6704..6970 | - | 267 | WP_001697809.1 | hypothetical protein | - |
| M1B75_RS24590 (6970) | 6970..7533 | - | 564 | WP_089552047.1 | class I SAM-dependent methyltransferase | - |
| M1B75_RS24595 (7579) | 7579..8940 | - | 1362 | WP_000170681.1 | DUF3560 domain-containing protein | - |
| M1B75_RS24600 (8992) | 8992..9222 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| M1B75_RS24605 (9739) | 9739..9992 | + | 254 | Protein_18 | hypothetical protein | - |
| M1B75_RS24610 (10216) | 10216..10398 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| M1B75_RS24615 (10398) | 10398..10859 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| M1B75_RS24620 (10859) | 10859..11284 | - | 426 | WP_001198922.1 | antirestriction protein | - |
| M1B75_RS24625 (11686) | 11686..12657 | + | 972 | WP_000082154.1 | IS110 family transposase ISEc32 | Transposase |
| M1B75_RS24630 (12918) | 12918..13130 | - | 213 | WP_000092896.1 | hypothetical protein | - |
| M1B75_RS24635 (13143) | 13143..13337 | - | 195 | WP_231532840.1 | hypothetical protein | - |
| M1B75_RS24645 (14160) | 14160..14495 | - | 336 | WP_000343070.1 | hypothetical protein | - |
| M1B75_RS24650 (14564) | 14564..14911 | - | 348 | WP_001350917.1 | hypothetical protein | - |
| M1B75_RS24655 (14908) | 14908..15077 | - | 170 | Protein_28 | hypothetical protein | - |
| M1B75_RS24660 (15843) | 15843..16814 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| M1B75_RS24665 (16814) | 16814..17980 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| M1B75_RS24675 (19133) | 19133..20635 | - | 1503 | WP_000715078.1 | hypothetical protein | - |
| M1B75_RS24680 (21112) | 21112..21809 | + | 698 | WP_223364178.1 | IS1-like element IS1B family transposase | - |
| M1B75_RS24685 (22048) | 22048..22473 | - | 426 | WP_012300440.1 | hypothetical protein | - |
| M1B75_RS24690 (22615) | 22615..23094 | + | 480 | WP_000190053.1 | hypothetical protein | - |
| M1B75_RS24695 (23534) | 23534..23785 | + | 252 | WP_013362826.1 | hypothetical protein | - |
| M1B75_RS24700 (23758) | 23758..23889 | - | 132 | Protein_37 | phosphopyruvate hydratase | - |
| M1B75_RS24705 (23887) | 23887..24144 | + | 258 | Protein_38 | Tn3 family transposase | - |
| M1B75_RS24710 (24378) | 24378..25235 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| M1B75_RS24715 (25232) | 25232..26089 | - | 858 | WP_000992806.1 | Manganese transport system membrane protein MntB | ARG |
| M1B75_RS24720 (26086) | 26086..26913 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| M1B75_RS24725 (26913) | 26913..27827 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| M1B75_RS24730 (28183) | 28183..28880 | + | 698 | WP_223155668.1 | IS1-like element IS1A family transposase | - |
| M1B75_RS24735 (29060) | 29060..29573 | - | 514 | Protein_44 | DUF4113 domain-containing protein | - |
| M1B75_RS24740 (29634) | 29634..29738 | - | 105 | Protein_45 | AAA family ATPase | - |
| M1B75_RS24745 (29740) | 29740..30063 | - | 324 | Protein_46 | IS21 family transposase IS21 | Transposase |
| M1B75_RS24750 (30809) | 30809..31786 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| M1B75_RS24755 (32071) | 32071..32811 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| M1B75_RS24760 (32932) | 32932..33120 | - | 189 | WP_033559363.1 | hypothetical protein | - |
| M1B75_RS24765 (33495) | 33495..34397 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| M1B75_RS24770 (34466) | 34466..35575 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| M1B75_RS24775 (36008) | 36008..36961 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| M1B75_RS24780 (38258) | 38258..38437 | - | 180 | Protein_53 | integrase core domain-containing protein | - |
| M1B75_RS24785 (38576) | 38576..38866 | + | 291 | Protein_54 | IS3 family transposase IS1203 | Transposase |
| M1B75_RS24790 (38934) | 38934..39631 | + | 698 | WP_103215986.1 | IS1-like element IS1A family transposase | - |
| M1B75_RS24795 (39709) | 39709..41098 | - | 1390 | Protein_56 | ISNCY family transposase ISKpn21 | Transposase |
| M1B75_RS24800 (41408) | 41408..41557 | - | 150 | Protein_57 | IS3 family transposase IS2 | Transposase |
| M1B75_RS24805 (41735) | 41735..42928 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| M1B75_RS24810 (44151) | 44151..45387 | - | 1237 | Protein_59 | IS3 family transposase IS2 | Transposase |
| M1B75_RS24815 (46014) | 46014..46307 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| M1B75_RS24820 (46391) | 46391..46539 | - | 149 | Protein_61 | Rz1 family lipoprotein | - |
| M1B75_RS24825 (46496) | 46496..46603 | - | 108 | Protein_62 | lysis system i-spanin subunit Rz | - |
| M1B75_RS24830 (47118) | 47118..48141 | + | 1024 | Protein_63 | integrase core domain-containing protein | - |
| M1B75_RS24835 (49452) | 49452..50567 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| M1B75_RS24840 (50707) | 50707..54366 | + | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| M1B75_RS24845 (54470) | 54470..55699 | + | 1230 | WP_001552738.1 | Enterochelin esterase | VF |
| M1B75_RS24850 (55784) | 55784..56740 | + | 957 | WP_032072160.1 | Ferri-bacillibactin esterase BesA | VF |
| M1B75_RS24855 (56785) | 56785..58962 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| M1B75_RS24865 (60262) | 60262..60336 | - | 75 | Protein_70 | colicin | - |
| M1B75_RS24870 (60314) | 60314..60550 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| M1B75_RS24875 (61092) | 61092..61295 | - | 204 | Protein_72 | hypothetical protein | - |
| M1B75_RS24880 (61468) | 61468..61635 | + | 168 | Protein_73 | colicin-B | - |
| M1B75_RS24885 (61653) | 61653..62180 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| M1B75_RS24890 (62424) | 62424..63239 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| M1B75_RS24895 (63289) | 63289..63642 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| M1B75_RS24900 (63819) | 63819..64610 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| M1B75_RS24905 (64607) | 64607..65296 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| M1B75_RS24910 (65340) | 65340..65690 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| M1B75_RS24915 (66289) | 66289..69498 | - | 3210 | WP_013362823.1 | hypothetical protein | - |
| M1B75_RS24920 (69887) | 69887..70144 | + | 258 | WP_013362822.1 | hypothetical protein | - |
| M1B75_RS24925 (70144) | 70144..70734 | + | 591 | WP_013362821.1 | hypothetical protein | - |
| M1B75_RS24930 (70999) | 70999..72555 | + | 1557 | WP_000818361.1 | AAA family ATPase | - |
| M1B75_RS24935 (72750) | 72750..72944 | + | 195 | Protein_84 | proQ/FINO family protein | - |
| M1B75_RS24940 (72977) | 72977..74728 | - | 1752 | Protein_85 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| M1B75_RS24945 (74732) | 74732..75124 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| M1B75_RS24950 (75262) | 75262..76146 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| M1B75_RS24955 (76178) | 76178..77377 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| M1B75_RS24960 (77483) | 77483..78133 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| M1B75_RS24965 (78165) | 78165..78407 | - | 243 | WP_000844627.1 | transposase | - |
| M1B75_RS24970 (79194) | 79194..79628 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| M1B75_RS24975 (79700) | 79700..80050 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| M1B75_RS24980 (80064) | 80064..80339 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| M1B75_RS24985 (80439) | 80439..83444 | - | 3006 | WP_001143760.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| M1B75_RS24990 (83608) | 83608..84165 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| M1B75_RS24995 (84348) | 84348..85208 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| M1B75_RS25000 (85390) | 85390..85752 | + | 363 | WP_048815731.1 | organomercurial transporter MerC | - |
| M1B75_RS25005 (85804) | 85804..87498 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| M1B75_RS25010 (87516) | 87516..87878 | + | 363 | WP_001277457.1 | mercury resistance co-regulator MerD | - |
| M1B75_RS25015 (87875) | 87875..88111 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| M1B75_RS25020 (88147) | 88147..88815 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| M1B75_RS25025 (88890) | 88890..90569 | + | 1680 | WP_000179844.1 | DDE-type integrase/transposase/recombinase | - |
| M1B75_RS25030 (90572) | 90572..91024 | + | 453 | Protein_103 | TniB family NTP-binding protein | - |
| M1B75_RS25035 (91130) | 91130..91630 | - | 501 | WP_000376623.1 | GNAT family N-acetyltransferase | - |
| M1B75_RS25040 (91758) | 91758..92597 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| M1B75_RS25045 (92591) | 92591..92938 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| M1B75_RS25050 (93055) | 93055..93893 | - | 839 | Protein_107 | Streptomycin 3''-adenylyltransferase | ARG |
| M1B75_RS25055 (93986) | 93986..94459 | - | 474 | WP_000777555.1 | Dihydrofolate reductase type 1 | ARG |
| M1B75_RS25060 (94616) | 94616..95629 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| M1B75_RS25065 (95832) | 95832..96182 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| M1B75_RS25070 (96259) | 96259..96903 | + | 645 | Protein_111 | STAS domain-containing protein | - |
| M1B75_RS25075 (96938) | 96938..97039 | + | 102 | Protein_112 | universal stress protein | - |
| M1B75_RS25080 (97095) | 97095..97792 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| M1B75_RS25085 (97794) | 97794..99314 | + | 1521 | WP_001301397.1 | Methyl-accepting chemotaxis protein McpQ | VF |
| M1B75_RS25090 (99507) | 99507..99932 | + | 426 | Protein_115 | ProQ/FINO family protein | - |
| M1B75_RS25095 (99991) | 99991..100983 | - | 993 | WP_001420353.1 | hypothetical protein | - |
| M1B75_RS25100 (101899) | 101899..102756 | - | 858 | WP_248638089.1 | incFII family plasmid replication initiator RepA | - |
| M1B75_RS25105 (102749) | 102749..102796 | - | 48 | WP_077822033.1 | hypothetical protein | - |
| M1B75_RS25110 (102787) | 102787..103023 | + | 237 | WP_223368648.1 | replication protein RepA | - |
| M1B75_RS25115 (103049) | 103049..103309 | - | 261 | WP_000083818.1 | replication regulatory protein RepA | - |
| M1B75_RS25120 (103548) | 103548..104121 | - | 574 | Protein_121 | DUF2726 domain-containing protein | - |
| M1B75_RS25125 (104159) | 104159..104368 | - | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| M1B75_RS25130 (104414) | 104414..104875 | - | 462 | WP_001233871.1 | thermonuclease family protein | - |
| M1B75_RS25135 (105118) | 105118..105330 | - | 213 | WP_012311405.1 | hypothetical protein | - |
| M1B75_RS25140 (105468) | 105468..106028 | - | 561 | WP_000139359.1 | fertility inhibition protein FinO | - |
| M1B75_RS25145 (106083) | 106083..106829 | - | 747 | WP_033559352.1 | conjugal transfer pilus acetylase TraX | - |
| M1B75_RS25150 (106849) | 106849..112119 | - | 5271 | WP_011117356.1 | Multifunctional conjugation protein TraI | Relaxase |
| M1B75_RS25155 (112201) | 112201..112428 | + | 228 | WP_000450532.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| M1B75_RS25160 (112428) | 112428..112826 | + | 399 | WP_000911324.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| M1B75_RS25165 (112835) | 112835..114988 | - | 2154 | WP_000009350.1 | type IV conjugative transfer system coupling protein TraD | - |
| M1B75_RS25170 (115241) | 115241..115972 | - | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| M1B75_RS25175 (115997) | 115997..116518 | - | 522 | WP_000632670.1 | conjugal transfer entry exclusion protein TraS | - |
| M1B75_RS25180 (116551) | 116551..119367 | - | 2817 | WP_001007054.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| M1B75_RS25185 (119364) | 119364..120737 | - | 1374 | WP_021553026.1 | conjugal transfer pilus assembly protein TraH | - |
| M1B75_RS25190 (120724) | 120724..121118 | - | 395 | Protein_135 | F-type conjugal transfer protein TrbF | - |
| M1B75_RS25195 (121105) | 121105..121446 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| M1B75_RS25200 (121376) | 121376..121921 | - | 546 | WP_000059850.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| M1B75_RS25205 (121908) | 121908..122192 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| M1B75_RS25210 (122273) | 122273..122587 | + | 315 | WP_000415567.1 | hypothetical protein | - |
| M1B75_RS25215 (122589) | 122589..122936 | - | 348 | WP_001287913.1 | conjugal transfer protein TrbA | - |
| M1B75_RS25220 (122952) | 122952..123695 | - | 744 | WP_001030367.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| M1B75_RS25225 (123688) | 123688..123945 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| M1B75_RS25230 (123972) | 123972..125780 | - | 1809 | WP_000821847.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| M1B75_RS25235 (125777) | 125777..126415 | - | 639 | WP_011117354.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| M1B75_RS25240 (126424) | 126424..127416 | - | 993 | WP_000830187.1 | conjugal transfer pilus assembly protein TraU | - |
| M1B75_RS25245 (127413) | 127413..128045 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| M1B75_RS25250 (128042) | 128042..128428 | - | 387 | WP_000097319.1 | type-F conjugative transfer system protein TrbI | - |
| M1B75_RS25255 (128425) | 128425..131052 | - | 2628 | WP_001064247.1 | type IV secretion system protein TraC | - |
| M1B75_RS25260 (131212) | 131212..131433 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| M1B75_RS25265 (131568) | 131568..132083 | - | 516 | WP_000809841.1 | type IV conjugative transfer system lipoprotein TraV | - |
| M1B75_RS25270 (132080) | 132080..132331 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| M1B75_RS25275 (132343) | 132343..132540 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| M1B75_RS25280 (132527) | 132527..133117 | - | 591 | WP_000002792.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| M1B75_RS25285 (133107) | 133107..134534 | - | 1428 | WP_000146692.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| M1B75_RS25290 (134534) | 134534..135262 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| M1B75_RS25295 (135249) | 135249..135815 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| M1B75_RS25300 (135837) | 135837..136148 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| M1B75_RS25305 (136163) | 136163..136528 | - | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| M1B75_RS25310 (136561) | 136561..136962 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| M1B75_RS25315 (137055) | 137055..137744 | - | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| M1B75_RS25320 (137931) | 137931..138314 | - | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| M1B75_RS25325 (138647) | 138647..139237 | + | 591 | WP_000252680.1 | hypothetical protein | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|