MGE detailed information
MGE type: Conjugative plasmid MGE length: 135067 bp
Accession: NZ_CP095539 Location: 1..135067 Organism: Escherichia coli strain GN04592 Replicon: plasmid p4592
Accession: NZ_CP095539 Location: 1..135067 Organism: Escherichia coli strain GN04592 Replicon: plasmid p4592
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MW396_RS25515 (171) | 171..362 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| MW396_RS25520 (359) | 359..781 | - | 423 | WP_000271708.1 | DUF1380 family protein | - |
| MW396_RS25525 (828) | 828..1253 | - | 426 | WP_001198903.1 | antirestriction protein | - |
| MW396_RS25530 (1669) | 1669..2439 | - | 771 | WP_001004562.1 | hypothetical protein | - |
| MW396_RS25535 (2484) | 2484..3002 | - | 519 | WP_223364201.1 | DUF1380 family protein | - |
| MW396_RS25540 (2932) | 2932..3153 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| MW396_RS25545 (3154) | 3154..3837 | - | 684 | WP_000086169.1 | DNA methylase | - |
| MW396_RS25550 (3913) | 3913..4224 | - | 312 | WP_001310011.1 | hypothetical protein | - |
| MW396_RS25555 (4221) | 4221..5123 | - | 903 | WP_001310012.1 | DUF1281 domain-containing protein | - |
| MW396_RS25560 (5542) | 5542..6762 | - | 1221 | WP_000343766.1 | ISL3 family transposase ISEc53 | Transposase |
| MW396_RS25565 (6781) | 6781..7299 | - | 519 | WP_000115885.1 | hypothetical protein | VF |
| MW396_RS25570 (7434) | 7434..7682 | + | 249 | WP_000619112.1 | DinI-like family protein | - |
| MW396_RS25575 (7679) | 7679..8116 | + | 438 | WP_000109079.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| MW396_RS25580 (8116) | 8116..9137 | + | 1022 | Protein_13 | translesion error-prone DNA polymerase V subunit UmuC | - |
| MW396_RS25585 (9239) | 9239..10411 | + | 1173 | WP_000952372.1 | IS21 family transposase IS21 | Transposase |
| MW396_RS25590 (10411) | 10411..11208 | + | 798 | WP_000544830.1 | IS21 family transposase IS21 | Transposase |
| MW396_RS25595 (11270) | 11270..11521 | + | 252 | Protein_16 | DUF4113 domain-containing protein | - |
| MW396_RS25600 (11526) | 11526..11918 | - | 393 | WP_000340835.1 | plasmid partitioning/stability family protein | - |
| MW396_RS25605 (11923) | 11923..12894 | - | 972 | WP_001103694.1 | plasmid segregation protein ParM | - |
| MW396_RS25610 (13123) | 13123..13767 | + | 645 | WP_000633911.1 | AAA family ATPase | - |
| MW396_RS25615 (13761) | 13761..14036 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| MW396_RS25620 (14174) | 14174..14983 | - | 810 | WP_000016979.1 | site-specific integrase | - |
| MW396_RS25625 (14984) | 14984..15289 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| MW396_RS25630 (15291) | 15291..15509 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| MW396_RS25635 (17831) | 17831..18277 | + | 447 | WP_251988392.1 | hypothetical protein | - |
| MW396_RS25640 (18341) | 18341..19687 | + | 1347 | WP_000483767.1 | IS4 family transposase IS4 | Transposase |
| MW396_RS25645 (19778) | 19778..20098 | - | 321 | WP_001363097.1 | hypothetical protein | - |
| MW396_RS25650 (21085) | 21085..22062 | + | 978 | WP_001309253.1 | RepB family plasmid replication initiator protein | - |
| MW396_RS25655 (22305) | 22305..23045 | - | 741 | WP_001066952.1 | tyrosine-type recombinase/integrase | - |
| MW396_RS25660 (23166) | 23166..23354 | - | 189 | WP_001309252.1 | hypothetical protein | - |
| MW396_RS25665 (23721) | 23721..24890 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| MW396_RS25670 (25116) | 25116..25291 | - | 176 | Protein_31 | IS3 family transposase | - |
| MW396_RS25675 (25737) | 25737..26009 | - | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| MW396_RS25680 (26546) | 26546..26970 | - | 425 | Protein_33 | IS3 family transposase IS2 | Transposase |
| MW396_RS25685 (27252) | 27252..29222 | + | 1971 | WP_001298664.1 | Hemin receptor | VF |
| MW396_RS25690 (29229) | 29229..30020 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| MW396_RS25695 (30083) | 30083..30691 | - | 609 | Protein_36 | IS66 family transposase ISEc22 | Transposase |
| MW396_RS25700 (30759) | 30759..31541 | - | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| MW396_RS25705 (31538) | 31538..32560 | - | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| MW396_RS25710 (32646) | 32646..33591 | - | 946 | Protein_39 | IS66 family transposase ISEc8 | Transposase |
| MW396_RS25715 (33640) | 33640..33987 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| MW396_RS25720 (33984) | 33984..34388 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| MW396_RS25725 (34468) | 34468..34806 | - | 339 | Protein_42 | IS3 family transposase IS629 | Transposase |
| MW396_RS25730 (34890) | 34890..36398 | - | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| MW396_RS25735 (37071) | 37071..37810 | - | 740 | Protein_44 | IS3 family transposase IS629 | Transposase |
| MW396_RS25740 (37836) | 37836..38141 | + | 306 | Protein_45 | IS91 family transposase ISSbo1 | Transposase |
| MW396_RS25745 (38664) | 38664..39839 | - | 1176 | WP_001020413.1 | putative protein YncE | VF |
| MW396_RS25750 (39908) | 39908..42169 | - | 2262 | WP_001100763.1 | TonB-dependent receptor | - |
| MW396_RS25755 (42338) | 42338..43114 | - | 777 | WP_000981091.1 | energy transducer TonB | - |
| MW396_RS25760 (43122) | 43122..43997 | - | 876 | WP_001224623.1 | ChaN family lipoprotein | - |
| MW396_RS25765 (44371) | 44371..44996 | - | 626 | Protein_50 | replication initiation protein | - |
| MW396_RS25770 (46448) | 46448..46783 | - | 336 | WP_001080732.1 | colicin E1 family microcin immunity protein | - |
| MW396_RS25775 (46912) | 46912..47259 | + | 348 | WP_000142452.1 | DUF6404 family protein | - |
| MW396_RS25780 (47279) | 47279..47788 | - | 510 | WP_000194542.1 | hypothetical protein | - |
| MW396_RS25785 (47785) | 47785..48045 | - | 261 | WP_000371882.1 | hypothetical protein | - |
| MW396_RS25790 (48147) | 48147..48886 | + | 740 | Protein_55 | IS3 family transposase IS629 | Transposase |
| MW396_RS25795 (49559) | 49559..49873 | + | 315 | Protein_56 | IS5 family transposase ISKpn26 | Transposase |
| MW396_RS25800 (49874) | 49874..50047 | + | 174 | Protein_57 | IS5 family transposase ISKpn26 | Transposase |
| MW396_RS25805 (50197) | 50197..50830 | - | 634 | Protein_58 | histidine-type phosphatase | - |
| MW396_RS25810 (50952) | 50952..51437 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| MW396_RS25815 (51462) | 51462..51947 | - | 486 | WP_001267176.1 | TlpA disulfide reductase family protein | - |
| MW396_RS25820 (51934) | 51934..52629 | - | 696 | WP_000117262.1 | Lipoprotein-releasing system ATP-binding protein LolD | VF |
| MW396_RS25825 (52634) | 52634..53764 | - | 1131 | WP_000729218.1 | ABC transporter permease | - |
| MW396_RS25830 (53754) | 53754..55037 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| MW396_RS25835 (55040) | 55040..56419 | - | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| MW396_RS25840 (56523) | 56523..57050 | - | 528 | WP_000178050.1 | iron transporter | - |
| MW396_RS25845 (57091) | 57091..58977 | - | 1887 | WP_000118029.1 | FTR1 family protein | - |
| MW396_RS25850 (59324) | 59324..60139 | - | 816 | WP_012372823.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| MW396_RS25855 (60322) | 60322..60828 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| MW396_RS25860 (60818) | 60818..60988 | - | 171 | Protein_69 | DsbA family protein | - |
| MW396_RS25865 (61126) | 61126..61239 | - | 114 | Protein_70 | IS6 family transposase | - |
| MW396_RS25870 (61439) | 61439..62136 | + | 698 | WP_151884388.1 | IS1 family transposase IS1X2 | Transposase |
| MW396_RS25875 (62152) | 62152..62499 | - | 348 | Protein_72 | Transposon Tn10 TetD protein | VF |
| MW396_RS25880 (62587) | 62587..63180 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| MW396_RS25885 (63293) | 63293..64498 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| MW396_RS25890 (64580) | 64580..65203 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| MW396_RS25895 (65181) | 65181..65867 | - | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| MW396_RS25900 (65875) | 65875..66009 | - | 135 | Protein_77 | amino acid-binding protein | - |
| MW396_RS25905 (66064) | 66064..66761 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| MW396_RS25910 (66868) | 66868..67302 | - | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| MW396_RS25915 (67374) | 67374..67724 | + | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| MW396_RS25920 (67738) | 67738..68013 | + | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| MW396_RS25925 (68049) | 68049..68471 | + | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| MW396_RS25930 (68523) | 68523..70217 | + | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| MW396_RS25935 (70235) | 70235..70597 | + | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| MW396_RS25940 (70594) | 70594..70830 | + | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| MW396_RS25945 (70866) | 70866..71534 | + | 669 | WP_001300294.1 | putative signaling protein | VF |
| MW396_RS25950 (71609) | 71609..72859 | + | 1251 | Protein_87 | transposase | - |
| MW396_RS25955 (72924) | 72924..73628 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MW396_RS25960 (73689) | 73689..74525 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| MW396_RS25965 (74525) | 74525..75328 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| MW396_RS25970 (75389) | 75389..76204 | - | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| MW396_RS25975 (76512) | 76512..77363 | - | 852 | WP_064772418.1 | replication protein C, IncQ-type | - |
| MW396_RS25980 (77350) | 77350..78069 | - | 720 | Protein_93 | helicase RepA family protein | - |
| MW396_RS25985 (78119) | 78119..78823 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MW396_RS25990 (78982) | 78982..79263 | - | 282 | Protein_95 | IS91 family transposase ISPps1 | Transposase |
| MW396_RS25995 (79410) | 79410..80270 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| MW396_RS26000 (80453) | 80453..80791 | - | 339 | Protein_97 | Tn3 family transposase TnpR_Tn3 | Transposase |
| MW396_RS26005 (80855) | 80855..81559 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| MW396_RS26010 (81617) | 81617..82059 | - | 443 | Protein_99 | IS1-like element IS1B family transposase | - |
| MW396_RS26015 (82308) | 82308..82709 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| MW396_RS26020 (82642) | 82642..82899 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| MW396_RS26025 (82992) | 82992..83645 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| MW396_RS26030 (84583) | 84583..85440 | - | 858 | WP_000131001.1 | incFII family plasmid replication initiator RepA | - |
| MW396_RS26035 (85433) | 85433..85507 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| MW396_RS26040 (85740) | 85740..86000 | - | 261 | WP_000078109.1 | replication regulatory protein RepA | - |
| MW396_RS26045 (86240) | 86240..86830 | - | 591 | WP_000766808.1 | DUF2726 domain-containing protein | - |
| MW396_RS26050 (86868) | 86868..87077 | - | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| MW396_RS26055 (87123) | 87123..87584 | - | 462 | WP_001233838.1 | thermonuclease family protein | - |
| MW396_RS26060 (87829) | 87829..88041 | - | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| MW396_RS26065 (88170) | 88170..88729 | - | 560 | Protein_110 | fertility inhibition protein FinO | - |
| MW396_RS26070 (88832) | 88832..89692 | - | 861 | WP_000704523.1 | putative protein YcjY | VF |
| MW396_RS26075 (89751) | 89751..90497 | - | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| MW396_RS26080 (90517) | 90517..95787 | - | 5271 | WP_000948348.1 | Multifunctional conjugation protein TraI | Relaxase |
| MW396_RS26085 (95787) | 95787..98039 | - | 2253 | WP_021526623.1 | type IV conjugative transfer system coupling protein TraD | - |
| MW396_RS26090 (98090) | 98090..98827 | - | 738 | WP_000199901.1 | hypothetical protein | - |
| MW396_RS26095 (99030) | 99030..99761 | - | 732 | WP_000782451.1 | conjugal transfer complement resistance protein TraT | - |
| MW396_RS26100 (99810) | 99810..100295 | - | 486 | WP_000605869.1 | hypothetical protein | - |
| MW396_RS26105 (100311) | 100311..103133 | - | 2823 | WP_001007080.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| MW396_RS26110 (103130) | 103130..104503 | - | 1374 | WP_000944331.1 | conjugal transfer pilus assembly protein TraH | - |
| MW396_RS26115 (104490) | 104490..104882 | - | 393 | WP_000660700.1 | F-type conjugal transfer protein TrbF | - |
| MW396_RS26120 (104863) | 104863..105210 | - | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| MW396_RS26125 (105140) | 105140..105685 | - | 546 | WP_000059830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| MW396_RS26130 (105672) | 105672..105956 | - | 285 | WP_000624107.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| MW396_RS26135 (106037) | 106037..106372 | + | 336 | WP_000736414.1 | hypothetical protein | - |
| MW396_RS26140 (106353) | 106353..106694 | - | 342 | WP_001298557.1 | conjugal transfer protein TrbA | - |
| MW396_RS26145 (106708) | 106708..107451 | - | 744 | WP_001030385.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| MW396_RS26150 (107444) | 107444..107701 | - | 258 | WP_000864314.1 | conjugal transfer protein TrbE | - |
| MW396_RS26155 (107728) | 107728..109578 | - | 1851 | WP_000821859.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| MW396_RS26160 (109575) | 109575..110213 | - | 639 | WP_001080251.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| MW396_RS26165 (110222) | 110222..110527 | - | 306 | WP_000224418.1 | hypothetical protein | - |
| MW396_RS26170 (110557) | 110557..111549 | - | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| MW396_RS26175 (111546) | 111546..112178 | - | 633 | WP_001203736.1 | type-F conjugative transfer system protein TraW | - |
| MW396_RS26180 (112175) | 112175..112561 | - | 387 | WP_000214082.1 | type-F conjugative transfer system protein TrbI | - |
| MW396_RS26185 (112558) | 112558..115188 | - | 2631 | WP_000069778.1 | type IV secretion system protein TraC | - |
| MW396_RS26190 (115555) | 115555..115773 | - | 219 | WP_000556746.1 | hypothetical protein | - |
| MW396_RS26195 (115853) | 115853..116326 | - | 474 | WP_000549566.1 | hypothetical protein | - |
| MW396_RS26200 (116319) | 116319..116540 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| MW396_RS26205 (116675) | 116675..117190 | - | 516 | WP_000809888.1 | type IV conjugative transfer system lipoprotein TraV | - |
| MW396_RS26210 (117187) | 117187..117439 | - | 253 | Protein_139 | conjugal transfer protein TrbG | - |
| MW396_RS26215 (117432) | 117432..117752 | - | 321 | WP_001057275.1 | conjugal transfer protein TrbD | - |
| MW396_RS26220 (117739) | 117739..118329 | - | 591 | WP_000002787.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| MW396_RS26225 (118319) | 118319..119746 | - | 1428 | WP_000146665.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| MW396_RS26230 (119746) | 119746..120474 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| MW396_RS26235 (120461) | 120461..121027 | - | 567 | WP_000399776.1 | type IV conjugative transfer system protein TraE | - |
| MW396_RS26240 (121049) | 121049..121360 | - | 312 | WP_000012100.1 | type IV conjugative transfer system protein TraL | - |
| MW396_RS26245 (121375) | 121375..121734 | - | 360 | WP_001098988.1 | type IV conjugative transfer system pilin TraA | - |
| MW396_RS26250 (121768) | 121768..121995 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| MW396_RS26255 (122089) | 122089..122775 | - | 687 | WP_000332487.1 | PAS domain-containing protein | - |
| MW396_RS26260 (122969) | 122969..123352 | - | 384 | WP_001151562.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| MW396_RS26265 (123683) | 123683..124285 | + | 603 | WP_001323326.1 | hypothetical protein | VF |
| MW396_RS26270 (124581) | 124581..125402 | - | 822 | WP_001234489.1 | DUF932 domain-containing protein | - |
| MW396_RS26275 (125521) | 125521..125808 | - | 288 | WP_000107526.1 | hypothetical protein | - |
| MW396_RS26280 (126109) | 126109..126406 | + | 298 | Protein_153 | hypothetical protein | - |
| MW396_RS26285 (126724) | 126724..126849 | - | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | - |
| MW396_RS26290 (126791) | 126791..126940 | - | 150 | Protein_155 | DUF5431 family protein | - |
| - (126947) | 126947..127146 | - | 200 | NuclAT_0 | - | - |
| - (126947) | 126947..127146 | - | 200 | NuclAT_0 | - | - |
| - (126947) | 126947..127146 | - | 200 | NuclAT_0 | - | - |
| - (126947) | 126947..127146 | - | 200 | NuclAT_0 | - | - |
| MW396_RS26295 (127114) | 127114..127877 | - | 764 | Protein_156 | plasmid SOS inhibition protein A | - |
| MW396_RS26300 (127874) | 127874..128308 | - | 435 | WP_000845910.1 | conjugation system SOS inhibitor PsiB | - |
| MW396_RS26305 (128363) | 128363..130306 | - | 1944 | WP_064772412.1 | ParB/RepB/Spo0J family partition protein | - |
| MW396_RS26310 (130365) | 130365..130598 | - | 234 | WP_000006018.1 | DUF905 domain-containing protein | - |
| MW396_RS26315 (130655) | 130655..131182 | - | 528 | WP_000290833.1 | single-stranded DNA-binding protein | - |
| MW396_RS26320 (131484) | 131484..131936 | + | 453 | WP_024185774.1 | hypothetical protein | - |
| MW396_RS26325 (132022) | 132022..132585 | - | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| MW396_RS26330 (132632) | 132632..133993 | - | 1362 | WP_000170671.1 | DUF3560 domain-containing protein | - |
| MW396_RS26335 (134045) | 134045..134275 | - | 231 | WP_000155844.1 | hypothetical protein | - |
| MW396_RS26340 (134788) | 134788..135067 | + | 280 | Protein_165 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|