MGE detailed information

MGE type: Conjugative plasmid        MGE length: 194916 bp
Accession: NZ_CP095133        Location: 1..194916         Organism: Klebsiella pneumoniae strain Iso00267       Replicon: plasmid pIso00267_01


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MU415_RS26525 1..1011 + 1011 WP_004152063.1 RepB family plasmid replication initiator protein -
MU415_RS26530 1728..2468 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
MU415_RS26535 3612..4559 + 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
MU415_RS26540 4586..4897 - 312 WP_071527918.1 EAL domain-containing protein -
MU415_RS26545 4917..5885 + 969 WP_011977741.1 IS5 family transposase IS903B Transposase
MU415_RS26550 6558..6815 - 258 WP_004197688.1 hypothetical protein -
MU415_RS26555 7456..7971 + 516 Protein_6 putative cyclic di-GMP phosphodiesterase PdeB VF
MU415_RS26560 8035..8871 + 837 WP_004178087.1 putative cyclic di-GMP phosphodiesterase PdeB VF
MU415_RS26565 9854..11131 - 1278 WP_004152070.1 DUF2254 domain-containing protein -
MU415_RS26570 11194..13191 - 1998 WP_004178088.1 choline BCCT transporter BetT -
MU415_RS26585 15529..16013 + 485 Protein_12 IS1 family transposase IS1X2 Transposase
MU415_RS26590 16029..16571 + 543 Protein_13 ISL3 family transposase ISKpn25 Transposase
MU415_RS26595 16867..17298 - 432 WP_004178091.1 silver-binding protein SilE -
MU415_RS26600 17549..19024 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
MU415_RS26605 19017..19697 - 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
MU415_RS26610 19887..21272 + 1386 WP_000475512.1 Cation efflux system protein CusC VF
MU415_RS26615 21301..21654 + 354 WP_001246153.1 cation efflux system protein CusF -
MU415_RS26620 21768..23060 + 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
MU415_RS26625 23071..26217 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
MU415_RS26630 26304..26744 + 441 WP_000758228.1 DUF411 domain-containing protein -
MU415_RS26635 26871..29318 + 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
MU415_RS26640 29359..29556 + 198 WP_000843497.1 DUF2933 domain-containing protein -
MU415_RS26645 29590..30327 - 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
MU415_RS26650 30616..31065 - 450 WP_001023257.1 copper resistance protein -
MU415_RS26655 31299..33116 + 1818 WP_000925242.1 multicopper oxidase PcoA -
MU415_RS26660 33122..34012 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
MU415_RS26665 34052..34432 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
MU415_RS26670 34437..35366 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
MU415_RS26675 35421..36101 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
MU415_RS26680 36098..37498 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
MU415_RS26685 37715..38149 + 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
MU415_RS26690 38381..38560 - 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
MU415_RS26695 38621..40241 - 1621 Protein_34 ISL3 family transposase ISEc38 Transposase
MU415_RS26700 40303..40812 + 510 WP_031944101.1 aquaporin -
MU415_RS26705 40862..41359 - 498 WP_004152091.1 GNAT family N-acetyltransferase -
MU415_RS26710 41691..42017 + 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
MU415_RS26715 42014..42727 + 714 WP_004152093.1 arsenical resistance protein ArsH -
MU415_RS26720 42736..43281 + 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
MU415_RS26725 43357..43719 + 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
MU415_RS26730 43738..45494 + 1757 Protein_41 arsenical pump-driving ATPase -
MU415_RS26735 45616..46152 + 537 WP_004152096.1 GNAT family N-acetyltransferase -
MU415_RS26740 46185..46610 - 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
MU415_RS26745 46623..47912 - 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
MU415_RS26750 47960..49711 - 1752 WP_004152099.1 Arsenical pump-driving ATPase VF
MU415_RS26755 49729..50091 - 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
MU415_RS26760 50141..50491 - 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
MU415_RS26765 50849..51097 + 249 WP_004200907.1 hypothetical protein -
MU415_RS26770 51094..52326 + 1233 WP_032249456.1 hypothetical protein -
MU415_RS26775 52460..52951 + 492 WP_032249453.1 hypothetical protein -
MU415_RS26780 53592..54560 - 969 WP_245146868.1 IS5 family transposase IS903B Transposase
MU415_RS26785 55242..55550 - 309 WP_017896554.1 hypothetical protein -
MU415_RS26790 56044..56592 + 549 WP_001567366.1 thioredoxin fold domain-containing protein -
MU415_RS26795 56639..57073 + 435 WP_001567367.1 cell envelope integrity protein TolA -
MU415_RS26800 57318..57584 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
MU415_RS26805 57572..58054 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
MU415_RS26810 58266..59612 + 1347 WP_020314316.1 ISNCY family transposase ISLad2 Transposase
MU415_RS28105 59773..59904 + 132 WP_004218042.1 hypothetical protein -
MU415_RS26815 60113..61278 - 1166 Protein_59 IS3 family transposase ISKpn38 Transposase
MU415_RS26820 61455..62417 - 963 WP_004152113.1 zinc metalloprotease HtpX -
MU415_RS26825 62404..62892 - 489 WP_004152114.1 phosphate-starvation-inducible PsiE family protein -
MU415_RS26830 63007..63153 - 147 Protein_62 diguanylate cyclase -
MU415_RS26835 63391..63588 - 198 WP_004152115.1 hypothetical protein -
MU415_RS26840 63588..66383 - 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
MU415_RS26845 66498..67067 - 570 WP_004152117.1 Spore protein SP21 VF
MU415_RS26850 67102..67383 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
MU415_RS26855 67627..67890 - 264 WP_004118208.1 hypothetical protein -
MU415_RS26860 67905..68168 + 264 WP_004118209.1 transposase -
MU415_RS26865 68113..68229 + 117 Protein_69 transposase domain-containing protein -
MU415_RS26870 68414..69111 + 698 WP_223174644.1 IS1 family transposase -
MU415_RS26875 69370..70350 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
MU415_RS26880 70932..71451 - 520 Protein_72 IS5 family transposase ISPst7 Transposase
MU415_RS26885 71559..72428 - 870 WP_245146869.1 HTH-type transcriptional activator CmpR VF
MU415_RS26890 72422..73432 - 1011 WP_004152693.1 phosphonate dehydrogenase PtxD -
MU415_RS26895 73441..74268 - 828 WP_004152694.1 phosphonate ABC transporter, permease protein PhnE -
MU415_RS26900 74277..75140 - 864 WP_004152695.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
MU415_RS26905 75137..75964 - 828 WP_004153729.1 Glutamine transport ATP-binding protein GlnQ VF
MU415_RS26910 76306..76614 + 309 Protein_78 IS5 family transposase ISThi1 Transposase
MU415_RS26915 76820..77524 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
MU415_RS26920 77608..78282 + 675 WP_004197529.1 Tn3 family transposase TnpR_TnEc1 Transposase
MU415_RS26925 78284..78610 + 327 WP_004197526.1 hypothetical protein -
MU415_RS26930 78646..79923 - 1278 WP_004197540.1 Y-family DNA polymerase -
MU415_RS26935 79929..80357 - 429 WP_004197551.1 S24 family peptidase -
MU415_RS26940 80453..80725 - 273 WP_004197545.1 helix-turn-helix transcriptional regulator -
MU415_RS26945 80850..81610 + 761 WP_085947932.1 IS5 family transposase ISKpn12 Transposase
MU415_RS26950 82502..82687 + 186 WP_004197549.1 hypothetical protein -
MU415_RS26955 82753..83235 - 483 Protein_87 IS3 family transposase ISKpn11 Transposase
MU415_RS26960 83304..84812 - 1509 WP_001189111.1 group II intron reverse transcriptase/maturase -
MU415_RS26965 85476..86161 - 686 Protein_89 IS3 family transposase ISKpn11 Transposase
MU415_RS26970 86247..86507 - 261 Protein_90 hypothetical protein -
MU415_RS26975 86520..87380 - 861 WP_000557452.1 SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD ARG
MU415_RS26980 87522..88382 - 861 WP_000027057.1 Beta-lactamase TEM ARG
MU415_RS26985 88565..89122 - 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
MU415_RS26990 89286..89504 + 219 WP_001143771.1 Tn3 family transposase TnpA_Tn3 Transposase
MU415_RS26995 89686..90948 + 1263 WP_000608644.1 IS1380 family transposase ISEcp1 Transposase
MU415_RS27000 91204..92079 + 876 WP_000239590.1 Beta-lactamase CTX-M-1 ARG
MU415_RS27005 92126..92470 - 345 Protein_97 WbuC family cupin fold metalloprotein -
MU415_RS27010 92484..95267 + 2784 Protein_98 Tn3 family transposase TnpA_Tn3 Transposase
MU415_RS27015 95287..95847 - 561 Protein_99 IS6 family transposase IS15DII Transposase
MU415_RS27020 95979..96215 - 237 WP_001087807.1 broad-spectrum mercury transporter MerE -
MU415_RS27025 96212..96577 - 366 WP_001277466.1 mercury resistance co-regulator MerD -
MU415_RS27030 96595..98280 - 1686 WP_000209296.1 mercury(II) reductase -
MU415_RS27035 98319..98744 - 426 WP_000522996.1 organomercurial transporter MerC -
MU415_RS27040 98772..99047 - 276 WP_000732275.1 mercury resistance system periplasmic binding protein MerP -
MU415_RS27045 99063..99443 - 381 WP_001294654.1 mercuric ion transporter MerT -
MU415_RS27050 99515..99970 + 456 WP_001166628.1 IS607 family transposase ISChh1 Transposase
MU415_RS27055 100080..101170 - 1091 Protein_107 IS3 family transposase ISEc36 Transposase
MU415_RS27060 101647..101919 + 273 WP_000333416.1 His-Xaa-Ser system protein HxsD -
MU415_RS27065 101919..103307 + 1389 WP_004118216.1 His-Xaa-Ser system radical SAM maturase HxsB -
MU415_RS27070 103300..104412 + 1113 WP_000005560.1 His-Xaa-Ser system radical SAM maturase HxsC -
MU415_RS27075 104409..105044 + 636 WP_004118217.1 His-Xaa-Ser repeat protein HxsA -
MU415_RS27080 106318..107175 - 858 WP_013023768.1 incFII family plasmid replication initiator RepA -
MU415_RS27085 107462..107740 - 279 WP_004099069.1 replication regulatory protein RepA -
MU415_RS27090 108060..108611 - 552 WP_013213996.1 Phospholipase D VF
MU415_RS27095 108716..108795 - 80 Protein_115 hypothetical protein -
MU415_RS27100 108897..109098 - 202 Protein_116 bacteriocin immunity protein -
MU415_RS27105 109211..110749 - 1539 WP_031944116.1 IS66 family transposase ISKpn24 Transposase
MU415_RS27110 110798..111145 - 348 WP_000612626.1 IS66 family transposase ISKpn24 Transposase
MU415_RS27115 111142..111546 - 405 WP_003031976.1 IS66 family transposase ISKpn24 Transposase
MU415_RS27120 111624..111779 + 156 Protein_120 IS3 family transposase ISEc14 Transposase
MU415_RS27125 112000..117735 - 5736 WP_021314612.1 DUF4011 domain-containing protein -
MU415_RS27130 117922..119964 - 2043 WP_013214046.1 DUF262 domain-containing protein -
MU415_RS27135 119957..121408 - 1452 WP_000443938.1 DUF262 domain-containing protein -
MU415_RS27140 121433..121741 - 309 Protein_124 IS3 family transposase ISLad1 Transposase
MU415_RS27145 121758..121997 - 240 Protein_125 IS110 family transposase -
MU415_RS27150 121996..122181 - 186 Protein_126 IS1 family transposase IS1A Transposase
MU415_RS27155 122268..123023 - 756 WP_009310009.1 SprT family zinc-dependent metalloprotease -
MU415_RS27160 123020..126304 - 3285 WP_013214044.1 type I restriction endonuclease subunit R -
MU415_RS27165 126357..127040 - 684 WP_001459731.1 YecA family protein -
MU415_RS27170 127037..128311 - 1275 WP_031944114.1 restriction endonuclease subunit S -
MU415_RS27175 128301..129824 - 1524 WP_013214042.1 type I restriction-modification system subunit M -
MU415_RS27180 130128..130825 - 698 Protein_132 IS1 family transposase -
MU415_RS27185 130957..131559 - 603 WP_015060010.1 PIN domain-containing protein -
MU415_RS27190 131720..132313 - 594 WP_023280883.1 fertility inhibition protein FinO -
MU415_RS27195 132470..133195 - 726 WP_031944112.1 type-F conjugative transfer system pilin acetylase TraX -
MU415_RS27200 133239..138500 - 5262 WP_031944111.1 Multifunctional conjugation protein TraI Relaxase
MU415_RS27205 138500..140812 - 2313 WP_031944110.1 type IV conjugative transfer system coupling protein TraD -
MU415_RS27210 141172..141903 - 732 WP_004152629.1 conjugal transfer complement resistance protein TraT -
MU415_RS27215 142093..142620 - 528 WP_004153030.1 hypothetical protein -
MU415_RS27220 142626..145475 - 2850 WP_004178054.1 conjugal transfer mating-pair stabilization protein TraG -
MU415_RS27225 145475..146845 - 1371 WP_004178055.1 conjugal transfer pilus assembly protein TraH -
MU415_RS27230 146832..147260 - 429 WP_004152689.1 hypothetical protein -
MU415_RS27235 147253..147825 - 573 WP_004152688.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
MU415_RS27240 147797..148036 - 240 WP_004152687.1 type-F conjugative transfer system pilin chaperone TraQ -
MU415_RS27245 148047..148799 - 753 WP_004152686.1 type-F conjugative transfer system pilin assembly protein TraF -
MU415_RS27250 148820..149146 - 327 WP_004152685.1 hypothetical protein -
MU415_RS27255 149374..149610 - 237 WP_004152683.1 conjugal transfer protein TrbE -
MU415_RS27260 149642..151597 - 1956 WP_004153093.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
MU415_RS27265 151645..152283 - 639 WP_004152682.1 type-F conjugative transfer system pilin assembly protein TrbC -
MU415_RS27270 152296..153255 - 960 WP_015065634.1 conjugal transfer pilus assembly protein TraU -
MU415_RS27275 153299..153925 - 627 WP_004152590.1 type-F conjugative transfer system protein TraW -
MU415_RS27280 153925..154314 - 390 WP_004152591.1 type-F conjugative transfer system protein TrbI -
MU415_RS27285 154314..156953 - 2640 WP_004152592.1 type IV secretion system protein TraC -
MU415_RS27290 157025..157423 - 399 WP_004153071.1 hypothetical protein -
MU415_RS27295 157719..158123 - 405 WP_031944109.1 hypothetical protein -
MU415_RS27300 158190..158507 - 318 WP_004152595.1 hypothetical protein -
MU415_RS27305 158508..158726 - 219 WP_004171484.1 hypothetical protein -
MU415_RS27310 158750..159040 - 291 WP_004152596.1 hypothetical protein -
MU415_RS27315 159045..159455 - 411 WP_004152597.1 lipase chaperone -
MU415_RS27320 159587..160156 - 570 WP_004152598.1 type IV conjugative transfer system lipoprotein TraV -
MU415_RS27325 160179..160775 - 597 WP_004152599.1 conjugal transfer pilus-stabilizing protein TraP -
MU415_RS27330 160768..162192 - 1425 WP_004152600.1 F-type conjugal transfer pilus assembly protein TraB -
MU415_RS27335 162192..162932 - 741 WP_004152601.1 type-F conjugative transfer system secretin TraK -
MU415_RS27340 162919..163485 - 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
MU415_RS27345 163505..163810 - 306 WP_004178059.1 type IV conjugative transfer system protein TraL -
MU415_RS27350 163824..164192 - 369 WP_004178060.1 type IV conjugative transfer system pilin TraA -
MU415_RS27355 164246..164617 - 372 WP_004208838.1 TraY domain-containing protein -
MU415_RS27360 164701..165396 - 696 WP_004178061.1 transcriptional regulator TraJ family protein -
MU415_RS27365 165610..166002 - 393 WP_004178062.1 conjugal transfer relaxosome DNA-binding protein TraM -
MU415_RS27370 166436..166921 + 486 WP_004178063.1 hypothetical protein VF
MU415_RS27375 166954..167283 - 330 WP_011977736.1 DUF5983 family protein -
MU415_RS27380 167316..168137 - 822 WP_004178064.1 DUF932 domain-containing protein -
MU415_RS27385 168971..169384 - 414 WP_004152722.1 helix-turn-helix domain-containing protein -
MU415_RS27390 169385..169663 - 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
MU415_RS27395 169653..169973 - 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
MU415_RS27400 170054..170278 - 225 WP_004152719.1 hypothetical protein -
MU415_RS27405 170289..170501 - 213 WP_004152718.1 hypothetical protein -
MU415_RS27410 170562..170918 - 357 WP_004152717.1 hypothetical protein -
MU415_RS27415 171554..171904 - 351 WP_004152758.1 hypothetical protein -
MU415_RS27420 171901..172173 - 273 WP_004152759.1 hypothetical protein -
MU415_RS27425 172873..173034 - 162 WP_004118124.1 type I toxin-antitoxin system Hok family toxin -
MU415_RS27430 173106..174185 + 1080 WP_004220208.1 IS481 family transposase ISKpn28 Transposase
MU415_RS27435 174363..174737 - 375 WP_004152638.1 hypothetical protein -
MU415_RS27440 174793..175119 - 327 WP_004152639.1 hypothetical protein -
MU415_RS27445 175116..175844 - 729 WP_004152640.1 plasmid SOS inhibition protein A -
MU415_RS27450 175841..176272 - 432 WP_004152641.1 conjugation system SOS inhibitor PsiB -
MU415_RS27455 176317..178375 - 2059 Protein_187 ParB/RepB/Spo0J family partition protein -
MU415_RS27460 178445..178693 - 249 WP_004152643.1 DUF905 domain-containing protein -
MU415_RS27465 178742..179284 - 543 WP_004152644.1 single-stranded DNA-binding protein -
MU415_RS27470 180060..180623 - 564 WP_004152645.1 methyltransferase -
MU415_RS27475 180671..182026 - 1356 WP_004178068.1 DUF3560 domain-containing protein -
MU415_RS27480 182078..182308 - 231 WP_004198570.1 hypothetical protein -
MU415_RS27485 182400..182627 - 228 WP_004178072.1 hypothetical protein -
MU415_RS27490 183409..183726 - 318 WP_004118473.1 hypothetical protein -
MU415_RS27495 183761..184015 - 255 WP_004152754.1 DNA polymerase III subunit theta -
MU415_RS27500 184252..184677 - 426 WP_004118478.1 antirestriction protein -
MU415_RS27505 185198..185428 - 231 WP_004152753.1 hypothetical protein -
MU415_RS27510 185662..187149 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
MU415_RS27515 187552..187977 + 426 WP_004178083.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
MU415_RS27520 187977..189248 + 1272 WP_004152715.1 Y-family DNA polymerase -
MU415_RS27525 189387..189542 + 156 WP_001776126.1 hypothetical protein -
MU415_RS27530 189565..190763 - 1199 Protein_202 IS200-IS605 family transposase IS609 Transposase
MU415_RS27535 192028..192999 - 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
MU415_RS27540 192999..194165 - 1167 WP_000523813.1 Sporulation initiation inhibitor protein Soj VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance