MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 159854 bp
Accession: NZ_CP095132 Location: 1688936..1848789 Organism: Klebsiella pneumoniae strain Iso00267 Replicon: chromosome
Accession: NZ_CP095132 Location: 1688936..1848789 Organism: Klebsiella pneumoniae strain Iso00267 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MU415_RS08260 (1684743) | 1684743..1685852 | + | 1110 | WP_002912751.1 | iron-sulfur cluster carrier protein ApbC | - |
| MU415_RS08265 (1685849) | 1685849..1686310 | - | 462 | WP_032104241.1 | GNAT family N-acetyltransferase | - |
| MU415_RS08270 (1686285) | 1686285..1686602 | - | 318 | WP_002912749.1 | RcnB family protein | - |
| MU415_RS08275 (1686786) | 1686786..1687685 | + | 900 | WP_004149074.1 | LysR family transcriptional regulator | - |
| MU415_RS08280 (1687675) | 1687675..1689018 | - | 1344 | WP_002912743.1 | NCS2 family permease | - |
| MU415_RS08285 (1689021) | 1689021..1690832 | - | 1812 | WP_094617159.1 | adenine deaminase C-terminal domain-containing protein | - |
| MU415_RS08290 (1690953) | 1690953..1691867 | + | 915 | WP_004175111.1 | LysR family transcriptional regulator | - |
| MU415_RS08295 (1691864) | 1691864..1692286 | - | 423 | WP_004151130.1 | universal stress protein | - |
| MU415_RS08300 (1692604) | 1692604..1693377 | + | 774 | WP_094617161.1 | hydroxyethylthiazole kinase | - |
| MU415_RS08305 (1693374) | 1693374..1694174 | + | 801 | WP_002912707.1 | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | - |
| MU415_RS08310 (1694322) | 1694322..1695374 | + | 1053 | WP_245146808.1 | class I fructose-bisphosphate aldolase | - |
| MU415_RS08315 (1695433) | 1695433..1696716 | - | 1284 | WP_016530940.1 | RbtT/DalT/CsbX family MFS transporter | - |
| MU415_RS08320 (1696798) | 1696798..1698405 | - | 1608 | WP_085163547.1 | FGGY-family carbohydrate kinase | - |
| MU415_RS08325 (1698432) | 1698432..1699181 | - | 750 | WP_004180592.1 | SDR family oxidoreductase | - |
| MU415_RS08330 (1699436) | 1699436..1700437 | + | 1002 | WP_004175120.1 | LacI family DNA-binding transcriptional regulator | - |
| MU415_RS08335 (1700460) | 1700460..1701401 | - | 942 | WP_004144198.1 | sugar-binding domain-containing protein | - |
| MU415_RS08340 (1701608) | 1701608..1702975 | + | 1368 | WP_094617163.1 | mannitol dehydrogenase family protein | - |
| MU415_RS08345 (1702985) | 1702985..1704448 | + | 1464 | WP_245146809.1 | xylulokinase | - |
| MU415_RS08350 (1704519) | 1704519..1705796 | + | 1278 | WP_032425105.1 | D-arabinitol transporter | - |
| MU415_RS08355 (1705845) | 1705845..1706507 | + | 663 | WP_038990546.1 | HAD-IA family hydrolase | - |
| MU415_RS08360 (1706805) | 1706805..1707959 | + | 1155 | WP_004189101.1 | mandelate racemase family protein | - |
| MU415_RS08365 (1708079) | 1708079..1709701 | + | 1623 | WP_004180553.1 | ABC transporter substrate-binding protein | - |
| MU415_RS08370 (1709698) | 1709698..1710735 | + | 1038 | WP_004149062.1 | ABC transporter permease | - |
| MU415_RS08375 (1710732) | 1710732..1711637 | + | 906 | WP_002912641.1 | ABC transporter permease | - |
| MU415_RS08380 (1711609) | 1711609..1712472 | + | 864 | WP_004180551.1 | Oligopeptide transport ATP-binding protein OppD | VF |
| MU415_RS08385 (1712483) | 1712483..1713256 | + | 774 | WP_087828054.1 | Oligopeptide transport ATP-binding protein OppF | VF |
| MU415_RS08390 (1713497) | 1713497..1714393 | - | 897 | WP_004151134.1 | lipid kinase YegS | - |
| MU415_RS08395 (1714636) | 1714636..1715997 | - | 1362 | WP_004144192.1 | tRNA 5-hydroxyuridine modification protein YegQ | - |
| MU415_RS08400 (1716316) | 1716316..1717038 | - | 723 | WP_004175198.1 | Transcriptional regulatory protein BaeR | VF |
| MU415_RS08405 (1717035) | 1717035..1718513 | - | 1479 | WP_004149058.1 | two-component system sensor histidine kinase BaeS | - |
| MU415_RS08410 (1718510) | 1718510..1719925 | - | 1416 | WP_004151136.1 | MFS transporter | - |
| MU415_RS08415 (1719927) | 1719927..1723004 | - | 3078 | WP_245146810.1 | Multidrug resistance protein MdtC | VF |
| MU415_RS08420 (1723005) | 1723005..1726127 | - | 3123 | WP_098947723.1 | Multidrug resistance protein MdtB | VF |
| MU415_RS08425 (1726127) | 1726127..1727365 | - | 1239 | WP_004198803.1 | Multidrug resistance protein MdtA | VF |
| MU415_RS08430 (1727708) | 1727708..1728940 | + | 1233 | WP_004233249.1 | dicarboxylate/amino acid:cation symporter | - |
| MU415_RS08435 (1729214) | 1729214..1729825 | - | 612 | WP_022631316.1 | positive transcription regulator | - |
| MU415_RS08440 (1729969) | 1729969..1730049 | - | 81 | WP_228958326.1 | hypothetical protein | - |
| MU415_RS08445 (1730319) | 1730319..1731020 | - | 702 | WP_004198790.1 | response regulator transcription factor | - |
| MU415_RS08450 (1731035) | 1731035..1732891 | - | 1857 | WP_040089335.1 | sensor histidine kinase | - |
| MU415_RS08455 (1733181) | 1733181..1734533 | - | 1353 | WP_023284036.1 | molecular chaperone | - |
| MU415_RS08460 (1734671) | 1734671..1735519 | + | 849 | WP_004151144.1 | DNA-3-methyladenine glycosylase 2 | - |
| MU415_RS08465 (1735634) | 1735634..1736275 | + | 642 | WP_002912442.1 | uridine kinase | - |
| MU415_RS08470 (1736366) | 1736366..1736947 | + | 582 | WP_004151145.1 | dCTP deaminase | - |
| MU415_RS08475 (1736978) | 1736978..1738825 | + | 1848 | WP_004180531.1 | outer membrane assembly protein AsmA | - |
| MU415_RS08480 (1739365) | 1739365..1740948 | - | 1584 | WP_004151147.1 | TerC family protein | - |
| MU415_RS08485 (1741708) | 1741708..1742681 | + | 974 | Protein_1661 | UTP--glucose-1-phosphate uridylyltransferase | VF |
| MU415_RS08490 (1742997) | 1742997..1743626 | + | 630 | WP_040170723.1 | hypothetical protein | VF |
| MU415_RS08495 (1744173) | 1744173..1744295 | - | 123 | WP_020324291.1 | hypothetical protein | - |
| MU415_RS08500 (1744586) | 1744586..1746025 | + | 1440 | WP_032409837.1 | hypothetical protein | VF |
| MU415_RS08505 (1746170) | 1746170..1747306 | + | 1137 | WP_032409838.1 | hypothetical protein | VF |
| MU415_RS08510 (1747309) | 1747309..1747743 | + | 435 | WP_032409839.1 | protein-tyrosine-phosphatase | - |
| MU415_RS08515 (1747760) | 1747760..1749925 | + | 2166 | WP_040170719.1 | Putative tyrosine-protein kinase in cps region | VF |
| MU415_RS08520 (1750038) | 1750038..1751465 | + | 1428 | WP_040170715.1 | UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase | VF |
| MU415_RS08525 (1751521) | 1751521..1752669 | + | 1149 | WP_087497820.1 | GDP-mannose-dependent monoacylated alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase | VF |
| MU415_RS08530 (1752680) | 1752680..1753711 | + | 1032 | WP_048254947.1 | hypothetical protein | - |
| MU415_RS08535 (1753708) | 1753708..1754727 | + | 1020 | WP_202110667.1 | Glycogen synthase | VF |
| MU415_RS08540 (1754750) | 1754750..1755916 | + | 1167 | WP_077256290.1 | O-antigen ligase family protein | - |
| MU415_RS08545 (1755913) | 1755913..1756860 | + | 948 | WP_040188829.1 | acyltransferase | - |
| MU415_RS08550 (1756863) | 1756863..1757942 | + | 1080 | WP_077256852.1 | glycosyltransferase | - |
| MU415_RS08555 (1757939) | 1757939..1759096 | + | 1158 | WP_094617175.1 | glycosyltransferase family 4 protein | - |
| MU415_RS08560 (1759093) | 1759093..1760406 | + | 1314 | WP_125027321.1 | hypothetical protein | - |
| MU415_RS08565 (1760576) | 1760576..1761982 | + | 1407 | WP_009307459.1 | 6-phosphogluconate dehydrogenase, decarboxylating | VF |
| MU415_RS08570 (1762225) | 1762225..1763640 | + | 1416 | WP_040169190.1 | Mannose-1-phosphate guanylyltransferase 1 | VF |
| MU415_RS08575 (1763663) | 1763663..1765033 | + | 1371 | WP_057729353.1 | Phosphomannomutase/phosphoglucomutase | VF |
| MU415_RS08580 (1765197) | 1765197..1766363 | + | 1167 | WP_004152483.1 | UDP-glucose 6-dehydrogenase | VF |
| MU415_RS08585 (1766786) | 1766786..1766908 | - | 123 | WP_032409012.1 | small membrane protein | - |
| MU415_RS08590 (1767307) | 1767307..1768311 | - | 1005 | WP_040169196.1 | UDP-N-acetylglucosamine 4-epimerase | VF |
| MU415_RS08595 (1769355) | 1769355..1770122 | + | 768 | WP_023287828.1 | Teichoic acid translocation permease protein TagG | VF |
| MU415_RS08600 (1770122) | 1770122..1770862 | + | 741 | WP_002912371.1 | Teichoic acids export ATP-binding protein TagH | VF |
| MU415_RS08605 (1770878) | 1770878..1772773 | + | 1896 | WP_094617177.1 | General stress protein A | VF |
| MU415_RS08610 (1772789) | 1772789..1773943 | + | 1155 | WP_023287826.1 | UDP-galactopyranose mutase | VF |
| MU415_RS08615 (1773940) | 1773940..1774833 | + | 894 | WP_004180501.1 | hypothetical protein | VF |
| MU415_RS08620 (1774834) | 1774834..1775979 | + | 1146 | WP_025983080.1 | N, N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase | VF |
| MU415_RS08625 (1776102) | 1776102..1777418 | + | 1317 | WP_023287822.1 | putative glycosyltransferase EpsJ | VF |
| MU415_RS08630 (1777522) | 1777522..1778121 | - | 600 | WP_004144136.1 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE | - |
| MU415_RS08635 (1778115) | 1778115..1778891 | - | 777 | WP_004180497.1 | imidazole glycerol phosphate synthase subunit HisF | - |
| MU415_RS08640 (1778873) | 1778873..1779610 | - | 738 | WP_015958687.1 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase | - |
| MU415_RS08645 (1779610) | 1779610..1780200 | - | 591 | WP_002912227.1 | imidazole glycerol phosphate synthase subunit HisH | - |
| MU415_RS08650 (1780200) | 1780200..1781267 | - | 1068 | WP_245146811.1 | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | - |
| MU415_RS08655 (1781264) | 1781264..1782325 | - | 1062 | WP_023278834.1 | histidinol-phosphate transaminase | - |
| MU415_RS08660 (1782322) | 1782322..1783626 | - | 1305 | WP_023287820.1 | histidinol dehydrogenase | - |
| MU415_RS08665 (1783666) | 1783666..1784565 | - | 900 | WP_002912152.1 | ATP phosphoribosyltransferase | - |
| MU415_RS08670 (1784711) | 1784711..1784761 | - | 51 | WP_004899375.1 | his operon leader peptide | - |
| MU415_RS08675 (1784938) | 1784938..1785762 | + | 825 | WP_004152513.1 | SDR family oxidoreductase | - |
| MU415_RS08680 (1785801) | 1785801..1786691 | + | 891 | WP_094617179.1 | LysR family transcriptional regulator | - |
| MU415_RS08685 (1786981) | 1786981..1788339 | + | 1359 | WP_004148994.1 | putrescine/proton symporter PlaP | - |
| MU415_RS08690 (1788482) | 1788482..1789845 | + | 1364 | WP_085955203.1 | IS3 family transposase ISKpn1 | Transposase |
| MU415_RS08695 (1789969) | 1789969..1790280 | - | 312 | WP_002912109.1 | helix-turn-helix domain-containing protein | - |
| MU415_RS08700 (1790520) | 1790520..1792622 | + | 2103 | WP_004899365.1 | elongation factor G | - |
| MU415_RS08705 (1792839) | 1792839..1794263 | - | 1425 | WP_019724958.1 | exodeoxyribonuclease I | - |
| MU415_RS08710 (1794444) | 1794444..1795607 | + | 1164 | WP_004153104.1 | serine-type D-Ala-D-Ala carboxypeptidase DacD | - |
| MU415_RS08715 (1795784) | 1795784..1796257 | + | 474 | WP_002911889.1 | DNA gyrase inhibitor SbmC | - |
| MU415_RS08720 (1796356) | 1796356..1797414 | + | 1059 | WP_002911885.1 | FUSC family protein | - |
| MU415_RS08725 (1797582) | 1797582..1797905 | + | 324 | WP_002911883.1 | DUF496 family protein | - |
| MU415_RS08730 (1798220) | 1798220..1798960 | + | 741 | WP_004180482.1 | adenosylcobinamide-GDP ribazoletransferase | - |
| MU415_RS08735 (1798988) | 1798988..1800055 | + | 1068 | WP_094617181.1 | nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | - |
| MU415_RS08740 (1800098) | 1800098..1801207 | - | 1110 | WP_004184774.1 | adenosylhomocysteinase | - |
| MU415_RS08745 (1801406) | 1801406..1802137 | + | 732 | WP_023307309.1 | HPP family protein | - |
| MU415_RS08750 (1802159) | 1802159..1802548 | - | 390 | WP_004189187.1 | tautomerase family protein | - |
| MU415_RS08755 (1802664) | 1802664..1803620 | + | 957 | WP_004180478.1 | HTH-type transcriptional regulator DmlR | VF |
| MU415_RS08760 (1803580) | 1803580..1804320 | - | 741 | WP_004189189.1 | hypothetical protein | - |
| MU415_RS08765 (1804367) | 1804367..1805686 | - | 1320 | WP_004899343.1 | shikimate transporter | - |
| MU415_RS08770 (1806030) | 1806030..1806491 | + | 462 | WP_014343289.1 | molybdopterin-dependent oxidoreductase | - |
| MU415_RS08775 (1806502) | 1806502..1808412 | + | 1911 | WP_004196289.1 | putative signaling protein | VF |
| MU415_RS08780 (1808409) | 1808409..1808537 | - | 129 | WP_004144110.1 | hypothetical protein | - |
| MU415_RS08785 (1808635) | 1808635..1808967 | + | 333 | WP_002911866.1 | DUF1971 domain-containing protein | - |
| MU415_RS08790 (1808974) | 1808974..1809309 | + | 336 | WP_004148980.1 | DUF1869 domain-containing protein | - |
| MU415_RS08795 (1809315) | 1809315..1810229 | - | 915 | WP_004189198.1 | LysR substrate-binding domain-containing protein | - |
| MU415_RS08800 (1810361) | 1810361..1810936 | + | 576 | WP_245146812.1 | hypothetical protein | - |
| MU415_RS08805 (1811129) | 1811129..1811965 | + | 837 | WP_004180471.1 | alpha/beta hydrolase | - |
| MU415_RS08810 (1812172) | 1812172..1813143 | + | 972 | WP_002911798.1 | sensor domain-containing diguanylate cyclase | - |
| MU415_RS08815 (1813140) | 1813140..1814243 | - | 1104 | WP_032412604.1 | AarF/UbiB family protein | - |
| MU415_RS08820 (1814397) | 1814397..1814471 | + | 75 | Protein_1728 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| MU415_RS08825 (1814880) | 1814880..1815860 | + | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| MU415_RS08830 (1815918) | 1815918..1816838 | + | 921 | WP_245146813.1 | hypothetical protein | - |
| MU415_RS08835 (1816917) | 1816917..1817474 | + | 558 | WP_020805022.1 | hypothetical protein | - |
| MU415_RS08840 (1817757) | 1817757..1818217 | + | 461 | Protein_1732 | hypothetical protein | - |
| MU415_RS08845 (1818214) | 1818214..1818420 | + | 207 | WP_020805021.1 | helix-turn-helix transcriptional regulator | - |
| MU415_RS08850 (1818755) | 1818755..1819012 | + | 258 | WP_000288812.1 | antitoxin | Antitoxin Detail |
| MU415_RS08855 (1819013) | 1819013..1819345 | + | 333 | WP_023341911.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| MU415_RS08860 (1819619) | 1819619..1820002 | + | 384 | Protein_1736 | helix-turn-helix domain-containing protein | - |
| MU415_RS08865 (1820005) | 1820005..1820133 | + | 129 | Protein_1737 | phage virion morphogenesis protein | - |
| MU415_RS08870 (1820268) | 1820268..1820519 | + | 252 | WP_001287855.1 | hypothetical protein | - |
| MU415_RS08875 (1820549) | 1820549..1821385 | + | 837 | WP_223175058.1 | hypothetical protein | - |
| MU415_RS08880 (1821405) | 1821405..1821560 | - | 156 | Protein_1740 | IS630 family transposase | - |
| MU415_RS08885 (1822041) | 1822041..1823141 | - | 1101 | WP_000659976.1 | reverse transcriptase domain-containing protein | - |
| MU415_RS08890 (1823256) | 1823256..1825532 | - | 2277 | WP_012602815.1 | retron Eco8 family effector endonuclease | - |
| MU415_RS08895 (1826607) | 1826607..1826678 | + | 72 | Protein_1743 | hypothetical protein | - |
| MU415_RS08900 (1826901) | 1826901..1827920 | + | 1020 | WP_001119745.1 | DUF4917 family protein | - |
| MU415_RS08905 (1828204) | 1828204..1830084 | - | 1881 | WP_000214431.1 | ATP-binding protein | - |
| MU415_RS08910 (1830081) | 1830081..1830575 | - | 495 | WP_000076577.1 | hypothetical protein | - |
| MU415_RS08915 (1830572) | 1830572..1831660 | - | 1089 | WP_000127329.1 | hypothetical protein | - |
| MU415_RS08920 (1831657) | 1831657..1832652 | - | 996 | WP_000996055.1 | restriction endonuclease | - |
| MU415_RS08925 (1833188) | 1833188..1833400 | - | 213 | WP_032194078.1 | JAB domain-containing protein | - |
| MU415_RS08930 (1833658) | 1833658..1834602 | + | 945 | WP_000155898.1 | zincin-like metallopeptidase domain-containing protein | - |
| MU415_RS08935 (1834795) | 1834795..1835541 | - | 747 | WP_000909124.1 | MobC family replication-relaxation protein | - |
| MU415_RS08940 (1835551) | 1835551..1837410 | - | 1860 | WP_000602685.1 | TraM recognition domain-containing protein | - |
| MU415_RS08945 (1838120) | 1838120..1838425 | - | 306 | WP_001168332.1 | hypothetical protein | - |
| MU415_RS08950 (1838470) | 1838470..1838772 | - | 303 | WP_001044654.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| MU415_RS08955 (1838808) | 1838808..1839211 | - | 404 | Protein_1755 | cag pathogenicity island Cag12 family protein | - |
| MU415_RS08960 (1839208) | 1839208..1840233 | - | 1026 | WP_000125557.1 | Type IV secretion system protein VirB11 | VF |
| MU415_RS08965 (1840223) | 1840223..1841485 | - | 1263 | WP_000997456.1 | Type IV secretion system protein virB10 | VF |
| MU415_RS08970 (1841529) | 1841529..1842437 | - | 909 | WP_000976329.1 | P-type conjugative transfer protein VirB9 | - |
| MU415_RS08975 (1842434) | 1842434..1843117 | - | 684 | WP_001005327.1 | Type IV secretion system protein PtlE | VF |
| MU415_RS08980 (1843110) | 1843110..1843247 | - | 138 | WP_000825478.1 | hypothetical protein | - |
| MU415_RS08985 (1843335) | 1843335..1844408 | - | 1074 | WP_000014008.1 | type IV secretion system protein | - |
| MU415_RS08990 (1844412) | 1844412..1844654 | - | 243 | WP_000949385.1 | EexN family lipoprotein | - |
| MU415_RS08995 (1844662) | 1844662..1845375 | - | 714 | WP_000848059.1 | type IV secretion system protein | - |
| MU415_RS09000 (1845394) | 1845394..1848132 | - | 2739 | WP_001096399.1 | Type IV secretion system protein virB4 | VF |
| MU415_RS09005 (1848145) | 1848145..1848438 | - | 294 | WP_000600171.1 | Type IV secretion system protein PtlA | VF |
| MU415_RS09010 (1848438) | 1848438..1849148 | - | 711 | WP_001446637.1 | lytic transglycosylase domain-containing protein | - |
| MU415_RS09015 (1849221) | 1849221..1849454 | - | 234 | WP_001231171.1 | hypothetical protein | - |
| MU415_RS09020 (1850023) | 1850023..1850151 | - | 129 | WP_000391562.1 | Hha/YmoA family nucleoid-associated regulatory protein | - |
| MU415_RS09025 (1850394) | 1850394..1850603 | - | 210 | WP_001112403.1 | TraR/DksA family transcriptional regulator | - |
| MU415_RS09030 (1850593) | 1850593..1851174 | - | 582 | WP_000937857.1 | DUF2857 domain-containing protein | - |
| MU415_RS09035 (1851159) | 1851159..1851341 | - | 183 | WP_001309570.1 | hypothetical protein | - |
| MU415_RS09040 (1851363) | 1851363..1851548 | - | 186 | WP_000205185.1 | AlpA family transcriptional regulator | - |
| MU415_RS09045 (1851688) | 1851688..1852614 | - | 927 | WP_000039790.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|