MGE detailed information
MGE type: Conjugative plasmid MGE length: 145622 bp
Accession: NZ_CP093460 Location: 1..145622 Organism: Klebsiella pneumoniae strain VA684 Replicon: plasmid pVA684-146
Accession: NZ_CP093460 Location: 1..145622 Organism: Klebsiella pneumoniae strain VA684 Replicon: plasmid pVA684-146
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MO416_RS26965 (MO416_26935) | 1..1011 | + | 1011 | WP_038992771.1 | RepB family plasmid replication initiator protein | - |
| MO416_RS26970 (MO416_26940) | 1729..2469 | - | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| MO416_RS26975 (MO416_26945) | 2838..3124 | - | 287 | Protein_2 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MO416_RS26980 (MO416_26950) | 3190..4158 | - | 969 | WP_072159537.1 | IS5 family transposase IS903B | Transposase |
| MO416_RS26985 (MO416_26955) | 4566..5474 | + | 909 | WP_032433744.1 | HNH endonuclease | - |
| MO416_RS26990 (MO416_26960) | 5862..6212 | - | 351 | WP_000694953.1 | DUF305 domain-containing protein | - |
| MO416_RS26995 (MO416_26965) | 6356..6787 | - | 432 | WP_032433720.1 | silver-binding protein SilE | - |
| MO416_RS27000 (MO416_26970) | 7038..8513 | - | 1476 | WP_032433718.1 | copper/silver sensor histidine kinase SilS | - |
| MO416_RS27005 (MO416_26975) | 8506..9186 | - | 681 | WP_032433715.1 | Transcriptional regulatory protein CusR | VF |
| MO416_RS27010 (MO416_26980) | 9376..10761 | + | 1386 | WP_000475515.1 | Cation efflux system protein CusC | VF |
| MO416_RS27015 (MO416_26985) | 10790..11143 | + | 354 | WP_032433713.1 | cation efflux system protein CusF | - |
| MO416_RS27020 (MO416_26990) | 11257..12549 | + | 1293 | WP_004098959.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| MO416_RS27025 (MO416_26995) | 12560..15706 | + | 3147 | WP_000574021.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| MO416_RS27030 (MO416_27000) | 15793..16233 | + | 441 | WP_000758228.1 | DUF411 domain-containing protein | - |
| MO416_RS27035 (MO416_27005) | 16360..18807 | + | 2448 | WP_101975956.1 | Ag(+)-translocating P-type ATPase SilP | - |
| MO416_RS27040 (MO416_27010) | 18848..19045 | + | 198 | WP_004388331.1 | DUF2933 domain-containing protein | - |
| MO416_RS27045 (MO416_27015) | 19079..19816 | - | 738 | WP_004388332.1 | Murein DD-endopeptidase MepM | VF |
| MO416_RS27050 (MO416_27020) | 20105..20554 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| MO416_RS27055 (MO416_27025) | 20789..22606 | + | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| MO416_RS27060 (MO416_27030) | 22612..23502 | + | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| MO416_RS27065 (MO416_27035) | 23542..23922 | + | 381 | WP_023316433.1 | copper resistance system metallochaperone PcoC | - |
| MO416_RS27070 (MO416_27040) | 23927..24856 | + | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| MO416_RS27075 (MO416_27045) | 24911..25591 | + | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| MO416_RS27080 (MO416_27050) | 25588..26988 | + | 1401 | WP_002436614.1 | copper resistance membrane spanning protein PcoS | - |
| MO416_RS27085 (MO416_27055) | 27204..27638 | + | 435 | WP_004118347.1 | hypothetical protein | - |
| MO416_RS27090 (MO416_27060) | 27817..27979 | - | 163 | Protein_25 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MO416_RS27095 (MO416_27065) | 28101..28280 | - | 180 | WP_101975955.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| MO416_RS27100 (MO416_27070) | 28442..28555 | - | 114 | Protein_27 | IS5/IS1182 family transposase | - |
| MO416_RS27105 (MO416_27075) | 28695..29042 | + | 348 | WP_127469808.1 | hypothetical protein | - |
| MO416_RS27110 (MO416_27080) | 29674..30927 | + | 1254 | WP_032432524.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| MO416_RS27115 (MO416_27085) | 30927..33170 | + | 2244 | WP_048269861.1 | Toxin RTX-I translocation ATP-binding protein | VF |
| MO416_RS27120 (MO416_27090) | 33186..33641 | - | 456 | Protein_31 | transposase domain-containing protein | - |
| MO416_RS27125 (MO416_27095) | 35169..35474 | + | 306 | WP_227522558.1 | CPBP family intramembrane metalloprotease | - |
| MO416_RS27130 (MO416_27100) | 35633..35885 | - | 253 | Protein_33 | IS3 family transposase ISKpn20 | Transposase |
| MO416_RS27135 (MO416_27105) | 36109..36375 | + | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| MO416_RS27140 (MO416_27110) | 36363..36845 | + | 483 | WP_003026803.1 | GNAT family N-acetyltransferase | Toxin Detail |
| MO416_RS27145 (MO416_27115) | 37111..37368 | - | 258 | WP_023292103.1 | hypothetical protein | - |
| MO416_RS27150 (MO416_27120) | 38010..38525 | + | 516 | Protein_37 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| MO416_RS27155 (MO416_27125) | 38589..39425 | + | 837 | WP_032409249.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| MO416_RS27160 (MO416_27130) | 39606..40220 | + | 615 | WP_023316428.1 | hypothetical protein | - |
| MO416_RS27165 (MO416_27135) | 40280..40408 | + | 129 | Protein_40 | transcriptional regulator | - |
| MO416_RS27170 (MO416_27140) | 40476..41441 | - | 966 | WP_004118146.1 | DMT family transporter | - |
| MO416_RS27175 (MO416_27145) | 41438..42256 | - | 819 | WP_004206594.1 | Glutamine transport ATP-binding protein GlnQ | VF |
| MO416_RS27180 (MO416_27150) | 42261..42923 | - | 663 | WP_004206593.1 | amino acid ABC transporter permease | - |
| MO416_RS27185 (MO416_27155) | 42920..43591 | - | 672 | WP_020325003.1 | amino acid ABC transporter permease | - |
| MO416_RS27190 (MO416_27160) | 43615..44463 | - | 849 | WP_004206591.1 | transporter substrate-binding domain-containing protein | - |
| MO416_RS27195 (MO416_27165) | 44619..45572 | + | 954 | WP_020806218.1 | Glycine cleavage system transcriptional activator | VF |
| MO416_RS27200 (MO416_27170) | 45659..46876 | + | 1218 | WP_004206589.1 | aminopeptidase P family protein | - |
| MO416_RS27205 (MO416_27175) | 46915..47034 | + | 120 | Protein_48 | IS21 family transposase | - |
| MO416_RS27210 (MO416_27180) | 47304..47373 | - | 70 | Protein_49 | hypothetical protein | - |
| MO416_RS27215 (MO416_27185) | 47510..48031 | + | 522 | WP_020325012.1 | putative RNA polymerase sigma factor FecI | VF |
| MO416_RS27220 (MO416_27190) | 48028..48981 | + | 954 | WP_020325007.1 | ferric citrate uptake sigma factor regulator FecR | - |
| MO416_RS27225 (MO416_27195) | 49068..51392 | + | 2325 | WP_020325014.1 | TonB-dependent Fe(3+) dicitrate receptor FecA | - |
| MO416_RS27230 (MO416_27200) | 51437..52339 | + | 903 | WP_004182127.1 | Fe(3+) dicitrate ABC transporter substrate-binding protein FecB | - |
| MO416_RS27235 (MO416_27205) | 52336..53334 | + | 999 | WP_004182126.1 | Fe(3+) dicitrate transport system permease protein FecC | VF |
| MO416_RS27240 (MO416_27210) | 53331..54287 | + | 957 | WP_004118246.1 | Fe(3+) dicitrate transport system permease protein FecD | VF |
| MO416_RS27245 (MO416_27215) | 54288..55055 | + | 768 | WP_283447402.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| MO416_RS27250 (MO416_27220) | 55154..55447 | + | 294 | WP_004118251.1 | IS66 family transposase ISKpn24 | Transposase |
| MO416_RS27255 (MO416_27225) | 55522..55749 | + | 228 | Protein_58 | IS66 family transposase | - |
| MO416_RS27260 (MO416_27230) | 55778..55975 | - | 198 | WP_072050298.1 | EAL domain-containing protein | - |
| MO416_RS27265 (MO416_27235) | 56318..57322 | - | 1005 | WP_000427614.1 | IS110 family transposase IS5075 | Transposase |
| MO416_RS27270 (MO416_27240) | 57726..58736 | - | 1011 | WP_277738759.1 | zinc-binding alcohol dehydrogenase family protein | - |
| MO416_RS27275 (MO416_27245) | 59197..60279 | + | 1083 | WP_004206569.1 | DNA-binding transcriptional repressor LacI | - |
| MO416_RS27280 (MO416_27250) | 60401..63475 | + | 3075 | WP_277738758.1 | beta-galactosidase | - |
| MO416_RS27285 (MO416_27255) | 63527..64780 | + | 1254 | WP_003846917.1 | lactose permease | - |
| MO416_RS27290 (MO416_27260) | 64846..64986 | + | 141 | Protein_65 | maltose acetyltransferase domain-containing protein | - |
| MO416_RS27295 (MO416_27265) | 65001..65694 | - | 694 | Protein_66 | IS1 family transposase | - |
| MO416_RS27300 (MO416_27270) | 65745..65894 | - | 150 | Protein_67 | creatininase family protein | - |
| MO416_RS27305 (MO416_27275) | 66070..67803 | - | 1734 | WP_004118832.1 | Glutathione import ATP-binding protein GsiA | VF |
| MO416_RS27310 (MO416_27280) | 67811..68758 | - | 948 | WP_023316423.1 | acetamidase/formamidase family protein | - |
| MO416_RS27315 (MO416_27285) | 68803..70407 | - | 1605 | WP_032409246.1 | ABC transporter substrate-binding protein | - |
| MO416_RS27320 (MO416_27290) | 70420..71340 | - | 921 | WP_004118227.1 | ABC transporter permease | - |
| MO416_RS27325 (MO416_27295) | 71340..72188 | - | 849 | WP_023316421.1 | ABC transporter permease | - |
| MO416_RS27330 (MO416_27300) | 72185..72778 | - | 594 | WP_004118229.1 | ANTAR domain-containing protein | - |
| MO416_RS27335 (MO416_27305) | 72775..73902 | - | 1128 | WP_023316420.1 | transporter substrate-binding protein | - |
| MO416_RS27340 (MO416_27310) | 74187..74288 | - | 102 | Protein_75 | integrase | - |
| MO416_RS27345 (MO416_27315) | 74283..74495 | + | 213 | WP_161989521.1 | hypothetical protein | - |
| MO416_RS27350 (MO416_27320) | 74701..74889 | - | 189 | Protein_77 | DUF2913 family protein | - |
| MO416_RS27355 (MO416_27325) | 75355..76350 | + | 996 | WP_032731913.1 | IS110 family transposase IS1663 | Transposase |
| MO416_RS27360 (MO416_27330) | 76588..77511 | - | 924 | WP_283447401.1 | phage exclusion protein Lit family protein | - |
| MO416_RS27365 (MO416_27335) | 78085..80394 | + | 2310 | WP_000421673.1 | TerB N-terminal domain-containing protein | - |
| MO416_RS27370 (MO416_27340) | 80398..81714 | + | 1317 | WP_023316417.1 | ATP-binding protein | - |
| MO416_RS27375 (MO416_27345) | 81711..83906 | + | 2196 | WP_000093087.1 | DEAD/DEAH box helicase | - |
| MO416_RS27380 (MO416_27350) | 85353..86210 | - | 858 | WP_040196868.1 | incFII family plasmid replication initiator RepA | - |
| MO416_RS27385 (MO416_27355) | 86497..86775 | - | 279 | WP_004199332.1 | replication regulatory protein RepA | - |
| MO416_RS27390 (MO416_27360) | 87096..87647 | - | 552 | WP_004152294.1 | Phospholipase D | VF |
| MO416_RS27395 (MO416_27365) | 87752..87832 | - | 81 | Protein_86 | hypothetical protein | - |
| MO416_RS27400 (MO416_27370) | 87916..88194 | - | 279 | WP_004152296.1 | bacteriocin immunity protein | - |
| MO416_RS27405 (MO416_27375) | 88196..90518 | - | 2323 | Protein_88 | klebicin B-related nuclease bacteriocin | - |
| MO416_RS27410 (MO416_27380) | 90875..91420 | + | 546 | WP_004206763.1 | hypothetical protein | - |
| MO416_RS27415 (MO416_27385) | 91634..91981 | - | 348 | WP_040196201.1 | DUF6404 family protein | - |
| MO416_RS27420 (MO416_27390) | 92001..92597 | - | 597 | WP_004178053.1 | fertility inhibition protein FinO | - |
| MO416_RS27425 (MO416_27395) | 92755..93480 | - | 726 | WP_004152303.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| MO416_RS27430 (MO416_27400) | 93560..98821 | - | 5262 | WP_101975970.1 | Multifunctional conjugation protein TraI | Relaxase |
| MO416_RS27435 (MO416_27405) | 98821..101130 | - | 2310 | WP_040196205.1 | type IV conjugative transfer system coupling protein TraD | - |
| MO416_RS27440 (MO416_27410) | 101490..102221 | - | 732 | WP_004152629.1 | conjugal transfer complement resistance protein TraT | - |
| MO416_RS27445 (MO416_27415) | 102411..102938 | - | 528 | WP_040196211.1 | conjugal transfer protein TraS | - |
| MO416_RS27450 (MO416_27420) | 102944..105793 | - | 2850 | WP_101975969.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| MO416_RS27455 (MO416_27425) | 105793..107163 | - | 1371 | WP_004178055.1 | conjugal transfer pilus assembly protein TraH | - |
| MO416_RS27460 (MO416_27430) | 107150..107578 | - | 429 | WP_023292146.1 | hypothetical protein | - |
| MO416_RS27465 (MO416_27435) | 107571..108143 | - | 573 | WP_023292147.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| MO416_RS27470 (MO416_27440) | 108115..108354 | - | 240 | WP_023292148.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| MO416_RS27475 (MO416_27445) | 108365..109117 | - | 753 | WP_004152686.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| MO416_RS27480 (MO416_27450) | 109138..109464 | - | 327 | WP_004152685.1 | hypothetical protein | - |
| MO416_RS27485 (MO416_27455) | 109692..109928 | - | 237 | WP_023292149.1 | conjugal transfer protein TrbE | - |
| MO416_RS27490 (MO416_27460) | 109960..111915 | - | 1956 | WP_101975968.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| MO416_RS27495 (MO416_27465) | 111974..112612 | - | 639 | WP_064182677.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| MO416_RS27500 (MO416_27470) | 112625..113584 | - | 960 | WP_029497356.1 | conjugal transfer pilus assembly protein TraU | - |
| MO416_RS27505 (MO416_27475) | 113628..114254 | - | 627 | WP_020314628.1 | type-F conjugative transfer system protein TraW | - |
| MO416_RS27510 (MO416_27480) | 114254..114643 | - | 390 | WP_020314627.1 | type-F conjugative transfer system protein TrbI | - |
| MO416_RS27515 (MO416_27485) | 114643..117282 | - | 2640 | WP_020323518.1 | type IV secretion system protein TraC | - |
| MO416_RS27520 (MO416_27490) | 117354..117752 | - | 399 | WP_072156904.1 | hypothetical protein | - |
| MO416_RS27525 (MO416_27495) | 117760..118050 | - | 291 | WP_101975967.1 | hypothetical protein | - |
| MO416_RS27530 (MO416_27500) | 118047..118451 | - | 405 | WP_023316404.1 | hypothetical protein | - |
| MO416_RS27535 (MO416_27505) | 118518..118829 | - | 312 | WP_023316403.1 | hypothetical protein | - |
| MO416_RS27540 (MO416_27510) | 118830..119048 | - | 219 | WP_023316402.1 | hypothetical protein | - |
| MO416_RS27545 (MO416_27515) | 119072..119356 | - | 285 | WP_023316401.1 | hypothetical protein | - |
| MO416_RS27550 (MO416_27520) | 119361..119771 | - | 411 | WP_023316400.1 | hypothetical protein | - |
| MO416_RS27555 (MO416_27525) | 119903..120472 | - | 570 | WP_023316399.1 | type IV conjugative transfer system lipoprotein TraV | - |
| MO416_RS27560 (MO416_27530) | 120495..121091 | - | 597 | WP_023316398.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| MO416_RS27565 (MO416_27535) | 121084..122508 | - | 1425 | WP_023316397.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| MO416_RS27570 (MO416_27540) | 122508..123248 | - | 741 | WP_020804840.1 | type-F conjugative transfer system secretin TraK | - |
| MO416_RS27575 (MO416_27545) | 123235..123801 | - | 567 | WP_101975966.1 | type IV conjugative transfer system protein TraE | - |
| MO416_RS27580 (MO416_27550) | 123821..124126 | - | 306 | WP_004178059.1 | type IV conjugative transfer system protein TraL | - |
| MO416_RS27585 (MO416_27555) | 124140..124508 | - | 369 | WP_004178060.1 | type IV conjugative transfer system pilin TraA | - |
| MO416_RS27590 (MO416_27560) | 124562..124933 | - | 372 | WP_004208838.1 | TraY domain-containing protein | - |
| MO416_RS27595 (MO416_27565) | 125017..125712 | - | 696 | WP_023292158.1 | transcriptional regulator TraJ family protein | - |
| MO416_RS27600 (MO416_27570) | 125919..126311 | - | 393 | WP_004178062.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| MO416_RS27605 (MO416_27575) | 126817..127224 | + | 408 | WP_225375048.1 | hypothetical protein | VF |
| MO416_RS27610 (MO416_27580) | 127262..127792 | - | 531 | WP_023292160.1 | antirestriction protein | - |
| MO416_RS27615 (MO416_27585) | 128417..129250 | - | 834 | WP_038990979.1 | N-6 DNA methylase | - |
| MO416_RS27620 (MO416_27590) | 129297..129527 | - | 231 | WP_038990977.1 | hypothetical protein | - |
| MO416_RS27625 (MO416_27595) | 129615..129962 | - | 348 | WP_038990975.1 | hypothetical protein | - |
| MO416_RS27630 (MO416_27600) | 130029..130409 | - | 381 | WP_038990973.1 | hypothetical protein | - |
| MO416_RS27635 (MO416_27605) | 131314..131433 | - | 120 | WP_223156217.1 | type I toxin-antitoxin system Hok family toxin | - |
| MO416_RS27640 (MO416_27610) | 131378..131530 | - | 153 | WP_224230667.1 | DUF5431 family protein | - |
| MO416_RS27645 (MO416_27615) | 131689..132015 | - | 327 | WP_038992719.1 | hypothetical protein | - |
| MO416_RS27650 (MO416_27620) | 132012..132740 | - | 729 | WP_040107916.1 | plasmid SOS inhibition protein A | - |
| MO416_RS27655 (MO416_27625) | 132737..133168 | - | 432 | WP_038992715.1 | conjugation system SOS inhibitor PsiB | - |
| MO416_RS27660 (MO416_27630) | 133213..135213 | - | 2001 | WP_040196882.1 | ParB/RepB/Spo0J family partition protein | - |
| MO416_RS27665 (MO416_27635) | 135282..135530 | - | 249 | WP_004206771.1 | DUF905 domain-containing protein | - |
| MO416_RS27670 (MO416_27640) | 135579..136121 | - | 543 | WP_038992711.1 | single-stranded DNA-binding protein | - |
| MO416_RS27675 (MO416_27645) | 136152..136355 | - | 204 | WP_072040208.1 | hypothetical protein | - |
| MO416_RS27680 (MO416_27650) | 136786..137106 | - | 321 | WP_032426243.1 | hypothetical protein | - |
| MO416_RS27685 (MO416_27655) | 137141..137395 | - | 255 | WP_004206775.1 | DNA polymerase III subunit theta | - |
| MO416_RS27690 (MO416_27660) | 137632..138057 | - | 426 | WP_004206777.1 | antirestriction protein | - |
| MO416_RS27695 (MO416_27665) | 138578..138808 | - | 231 | WP_004206779.1 | hypothetical protein | - |
| MO416_RS27700 (MO416_27670) | 139023..139448 | + | 426 | WP_038992708.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| MO416_RS27705 (MO416_27675) | 139448..140719 | + | 1272 | WP_004206782.1 | Y-family DNA polymerase | - |
| MO416_RS27710 (MO416_27680) | 140798..141049 | + | 252 | WP_040196886.1 | plasmid stabilization protein | - |
| MO416_RS27715 (MO416_27685) | 141103..141408 | + | 306 | WP_040196888.1 | hypothetical protein | - |
| MO416_RS27720 (MO416_27690) | 142735..143706 | - | 972 | WP_004206785.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| MO416_RS27725 (MO416_27695) | 143706..144872 | - | 1167 | WP_000523812.1 | Sporulation initiation inhibitor protein Soj | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|