MGE detailed information
MGE type: Conjugative plasmid MGE length: 96053 bp
Accession: NZ_CP093320 Location: 1..96053 Organism: Escherichia coli strain HUM3355 Replicon: plasmid pHUM3355_C
Accession: NZ_CP093320 Location: 1..96053 Organism: Escherichia coli strain HUM3355 Replicon: plasmid pHUM3355_C
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MLA23_RS24520 (1) | 1..1032 | + | 1032 | WP_000907873.1 | plasmid replication initiator RepA | - |
| MLA23_RS24525 (1728) | 1728..1886 | + | 159 | WP_000841008.1 | hypothetical protein | - |
| MLA23_RS24530 (1941) | 1941..2210 | + | 270 | WP_000079941.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| MLA23_RS24535 (2210) | 2210..2488 | + | 279 | WP_244442846.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| MLA23_RS24540 (2528) | 2528..3376 | + | 849 | WP_001057991.1 | 3'-5' exonuclease | - |
| MLA23_RS24545 (3493) | 3493..3966 | + | 474 | WP_001334658.1 | hypothetical protein | - |
| MLA23_RS24550 (4443) | 4443..4709 | - | 267 | WP_000955263.1 | hypothetical protein | - |
| MLA23_RS24555 (4709) | 4709..5203 | - | 495 | WP_001459505.1 | hypothetical protein | - |
| MLA23_RS24560 (5259) | 5259..5861 | - | 603 | WP_000517695.1 | ProQ/FINO family protein | - |
| MLA23_RS24565 (6215) | 6215..7561 | + | 1347 | WP_001132032.1 | protein YagA | - |
| MLA23_RS24570 (7840) | 7840..9720 | + | 1881 | WP_001283341.1 | colicin Ia central receptor-binding domain-containing protein | - |
| MLA23_RS24575 (9738) | 9738..10085 | - | 348 | WP_000762570.1 | colicin 1B immunity protein | - |
| MLA23_RS24580 (10204) | 10204..10410 | + | 207 | Protein_12 | DUF6404 family protein | - |
| MLA23_RS24585 (10593) | 10593..11855 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| MLA23_RS24590 (12179) | 12179..13324 | + | 1146 | WP_000976514.1 | Beta-lactamase | ARG |
| MLA23_RS24595 (13485) | 13485..13634 | + | 150 | Protein_15 | DUF6404 family protein | - |
| MLA23_RS24600 (13652) | 13652..14242 | - | 591 | WP_000194550.1 | hypothetical protein | - |
| MLA23_RS24605 (14242) | 14242..14496 | - | 255 | WP_000343103.1 | hypothetical protein | - |
| MLA23_RS24610 (14848) | 14848..15849 | + | 1002 | WP_000774874.1 | DUF4238 domain-containing protein | - |
| MLA23_RS24615 (16025) | 16025..16369 | - | 345 | WP_000793307.1 | hypothetical protein | - |
| MLA23_RS24620 (16868) | 16868..17122 | - | 255 | WP_000678527.1 | hypothetical protein | - |
| MLA23_RS24625 (17167) | 17167..18093 | - | 927 | WP_001290416.1 | hypothetical protein | - |
| MLA23_RS24630 (18625) | 18625..19038 | + | 414 | WP_000465043.1 | hypothetical protein | - |
| MLA23_RS24635 (19040) | 19040..19819 | + | 780 | WP_021537353.1 | site-specific integrase | - |
| MLA23_RS24640 (19999) | 19999..20643 | + | 645 | WP_001144036.1 | ParA family protein | - |
| MLA23_RS24645 (20730) | 20730..21038 | + | 309 | WP_000030199.1 | hypothetical protein | - |
| MLA23_RS24650 (21452) | 21452..22432 | + | 981 | WP_000688514.1 | plasmid segregation protein ParM | - |
| MLA23_RS24655 (22425) | 22425..22841 | + | 417 | WP_001278818.1 | plasmid partitioning/stability family protein | - |
| MLA23_RS24660 (22843) | 22843..24117 | - | 1275 | WP_000457493.1 | Y-family DNA polymerase | - |
| MLA23_RS24665 (24117) | 24117..24554 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| MLA23_RS24670 (24551) | 24551..24799 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| MLA23_RS24675 (25217) | 25217..26119 | + | 903 | WP_000273918.1 | DUF1281 domain-containing protein | - |
| MLA23_RS24680 (26116) | 26116..26427 | + | 312 | WP_010891263.1 | hypothetical protein | - |
| MLA23_RS24685 (26504) | 26504..27187 | + | 684 | WP_000086178.1 | DNA methylase | - |
| MLA23_RS24690 (27188) | 27188..27409 | + | 222 | WP_001104887.1 | hypothetical protein | - |
| MLA23_RS24695 (27369) | 27369..27855 | + | 487 | Protein_35 | DUF1380 domain-containing protein | - |
| MLA23_RS24700 (27906) | 27906..28676 | + | 771 | WP_024133193.1 | hypothetical protein | - |
| MLA23_RS24705 (29094) | 29094..29519 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| MLA23_RS24710 (29566) | 29566..29988 | + | 423 | WP_000271725.1 | DUF1380 family protein | - |
| MLA23_RS24715 (29985) | 29985..30176 | + | 192 | WP_001027500.1 | hypothetical protein | - |
| MLA23_RS24720 (30247) | 30247..30594 | + | 348 | WP_001303314.1 | hypothetical protein | - |
| MLA23_RS24725 (30946) | 30946..31473 | + | 528 | WP_001276116.1 | single-stranded DNA-binding protein | - |
| MLA23_RS24730 (31531) | 31531..31764 | + | 234 | WP_000006012.1 | DUF905 family protein | - |
| MLA23_RS24735 (31823) | 31823..33781 | + | 1959 | WP_001145458.1 | ParB/RepB/Spo0J family partition protein | - |
| MLA23_RS24740 (33836) | 33836..34270 | + | 435 | WP_000845897.1 | conjugation system SOS inhibitor PsiB | - |
| MLA23_RS24745 (34267) | 34267..34986 | + | 720 | WP_001276260.1 | plasmid SOS inhibition protein A | - |
| MLA23_RS24750 (35116) | 35116..36291 | + | 1176 | WP_000942657.1 | IS200-IS605 family transposase ISEc46 | Transposase |
| MLA23_RS24755 (36738) | 36738..37238 | + | 501 | WP_000117611.1 | antirestriction protein ArdA | - |
| MLA23_RS24760 (37967) | 37967..38401 | + | 435 | WP_000218863.1 | hypothetical protein | - |
| MLA23_RS24765 (38493) | 38493..38759 | + | 267 | WP_001247862.1 | hypothetical protein | - |
| MLA23_RS24770 (38824) | 38824..39726 | + | 903 | WP_039005633.1 | Recombination-promoting nuclease RpnA | VF |
| MLA23_RS24775 (39726) | 39726..40019 | + | 294 | WP_077250487.1 | hypothetical protein | VF |
| MLA23_RS24780 (40050) | 40050..40301 | - | 252 | WP_000148286.1 | helix-turn-helix transcriptional regulator | - |
| MLA23_RS24785 (40335) | 40335..40532 | - | 198 | WP_001161115.1 | hypothetical protein | - |
| MLA23_RS24790 (40881) | 40881..41729 | + | 849 | WP_001077027.1 | DUF4942 domain-containing protein | - |
| MLA23_RS24795 (41815) | 41815..42150 | - | 336 | WP_000157086.1 | molybdopterin-guanine dinucleotide biosynthesis protein MobC | - |
| MLA23_RS24800 (42384) | 42384..42716 | + | 333 | WP_052940647.1 | IncI1-type relaxosome accessory protein NikA | - |
| MLA23_RS24805 (42727) | 42727..45426 | + | 2700 | WP_001474686.1 | Protein TraI | Relaxase |
| MLA23_RS24810 (45463) | 45463..47754 | - | 2292 | WP_001289271.1 | F-type conjugative transfer protein TrbC | - |
| MLA23_RS24815 (47747) | 47747..48817 | - | 1071 | WP_000151575.1 | IncI1-type conjugal transfer protein TrbB | - |
| MLA23_RS24820 (48836) | 48836..50044 | - | 1209 | WP_000121273.1 | IncI1-type conjugal transfer protein TrbA | - |
| - (50224) | 50224..50286 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (50224) | 50224..50286 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (50224) | 50224..50286 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (50224) | 50224..50286 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| MLA23_RS24825 (50336) | 50336..50488 | + | 153 | WP_001303307.1 | Hok/Gef family protein | Toxin Detail |
| MLA23_RS24830 (50560) | 50560..50811 | - | 252 | WP_001291965.1 | hypothetical protein | - |
| - (51198) | 51198..51249 | - | 52 | NuclAT_1 | - | - |
| - (51198) | 51198..51249 | - | 52 | NuclAT_1 | - | - |
| - (51198) | 51198..51249 | - | 52 | NuclAT_1 | - | - |
| - (51198) | 51198..51249 | - | 52 | NuclAT_1 | - | - |
| MLA23_RS24835 (51735) | 51735..51911 | - | 177 | WP_001054900.1 | hypothetical protein | - |
| MLA23_RS24840 (52303) | 52303..52512 | + | 210 | WP_000062603.1 | HEAT repeat domain-containing protein | - |
| MLA23_RS24845 (52584) | 52584..53246 | - | 663 | WP_000644794.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| MLA23_RS24850 (53317) | 53317..55485 | - | 2169 | WP_000698368.1 | DotA/TraY family protein | - |
| MLA23_RS24855 (55582) | 55582..56166 | - | 585 | WP_001037998.1 | conjugal transfer protein TraX | - |
| MLA23_RS24860 (56195) | 56195..57397 | - | 1203 | WP_001189158.1 | IncI1-type conjugal transfer protein TraW | - |
| MLA23_RS24865 (57364) | 57364..57978 | - | 615 | WP_000337394.1 | IncI1-type conjugal transfer protein TraV | - |
| MLA23_RS24870 (57978) | 57978..61022 | - | 3045 | WP_001024752.1 | IncI1-type conjugal transfer protein TraU | - |
| MLA23_RS24875 (61112) | 61112..61912 | - | 801 | WP_001164788.1 | IncI1-type conjugal transfer protein TraT | - |
| MLA23_RS24880 (61896) | 61896..62084 | - | 189 | WP_001277255.1 | putative conjugal transfer protein TraS | - |
| MLA23_RS24885 (62148) | 62148..62552 | - | 405 | WP_000086960.1 | IncI1-type conjugal transfer protein TraR | - |
| MLA23_RS24890 (62603) | 62603..63130 | - | 528 | WP_001055569.1 | conjugal transfer protein TraQ | - |
| MLA23_RS24895 (63130) | 63130..63834 | - | 705 | WP_000801920.1 | IncI1-type conjugal transfer protein TraP | - |
| MLA23_RS24900 (63834) | 63834..65123 | - | 1290 | WP_001271997.1 | conjugal transfer protein TraO | - |
| MLA23_RS24905 (65126) | 65126..66109 | - | 984 | WP_001191878.1 | hypothetical protein | VF |
| MLA23_RS24910 (66120) | 66120..66812 | - | 693 | WP_000138552.1 | DotI/IcmL family type IV secretion protein | - |
| MLA23_RS24915 (66809) | 66809..67156 | - | 348 | WP_001055900.1 | conjugal transfer protein | - |
| MLA23_RS24920 (67174) | 67174..70941 | - | 3768 | WP_001141535.1 | DUF5710 domain-containing protein | - |
| MLA23_RS24925 (71031) | 71031..71582 | - | 552 | WP_000014584.1 | Phospholipase D | VF |
| MLA23_RS24930 (71597) | 71597..71887 | - | 291 | WP_001299214.1 | hypothetical protein | - |
| MLA23_RS24935 (71884) | 71884..73032 | - | 1149 | WP_001024972.1 | putative protein YggR | VF |
| MLA23_RS24940 (73029) | 73029..73847 | - | 819 | WP_000646097.1 | hypothetical protein | VF |
| MLA23_RS24945 (73844) | 73844..74302 | - | 459 | WP_001079808.1 | hypothetical protein | VF |
| MLA23_RS24950 (74697) | 74697..75281 | - | 585 | WP_000977517.1 | histidine phosphatase family protein | - |
| MLA23_RS24955 (75341) | 75341..76543 | - | 1203 | WP_000976353.1 | conjugal transfer protein TraF | - |
| MLA23_RS24960 (76629) | 76629..77453 | - | 825 | WP_001238927.1 | conjugal transfer protein TraE | - |
| MLA23_RS24965 (77604) | 77604..78758 | - | 1155 | WP_001139958.1 | site-specific integrase | - |
| MLA23_RS24970 (79449) | 79449..79697 | + | 249 | WP_001349157.1 | hypothetical protein | - |
| MLA23_RS24975 (79694) | 79694..80986 | - | 1293 | WP_032274560.1 | hypothetical protein | VF |
| MLA23_RS24980 (80986) | 80986..81642 | - | 657 | WP_001193553.1 | hypothetical protein | VF |
| MLA23_RS24985 (81627) | 81627..82187 | - | 561 | WP_000014116.1 | hypothetical protein | VF |
| MLA23_RS24990 (82197) | 82197..82811 | - | 615 | WP_000959785.1 | hypothetical protein | VF |
| MLA23_RS24995 (82829) | 82829..83926 | - | 1098 | WP_001208805.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| MLA23_RS25000 (83939) | 83939..85492 | - | 1554 | WP_000362202.1 | Toxin coregulated pilus biosynthesis protein T | VF |
| MLA23_RS25005 (85503) | 85503..85955 | - | 453 | WP_001247336.1 | hypothetical protein | VF |
| MLA23_RS25010 (85942) | 85942..87237 | - | 1296 | WP_000752774.1 | type 4b pilus protein PilO2 | - |
| MLA23_RS25015 (87230) | 87230..88912 | - | 1683 | WP_000748143.1 | Outer membrane lipoprotein BfpB | VF |
| MLA23_RS25020 (88926) | 88926..89363 | - | 438 | WP_000539807.1 | hypothetical protein | VF |
| MLA23_RS25025 (89363) | 89363..90430 | - | 1068 | WP_000742600.1 | hypothetical protein | VF |
| MLA23_RS25030 (91104) | 91104..91556 | - | 453 | WP_000008892.1 | hypothetical protein | - |
| MLA23_RS25035 (91599) | 91599..91853 | - | 255 | WP_001136192.1 | PilI type IV pilus biogenesis protein | - |
| MLA23_RS25040 (92121) | 92121..92687 | - | 567 | WP_000776428.1 | protein TraD | - |
| MLA23_RS25045 (92701) | 92701..93384 | - | 684 | WP_000213857.1 | conjugal transfer protein TraC | - |
| MLA23_RS25050 (93638) | 93638..94171 | - | 534 | WP_001303319.1 | transcription termination/antitermination NusG family protein | - |
| MLA23_RS25055 (94613) | 94613..94900 | - | 288 | WP_000074849.1 | conjugal transfer protein TraA | - |
| MLA23_RS25060 (94818) | 94818..95048 | - | 231 | WP_228772074.1 | ash family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|