MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 83629 bp
Accession: NZ_CP092571 Location: 1..83629 Organism: Enterococcus faecium strain VRE-WC072 Replicon: plasmid unnamed2
Accession: NZ_CP092571 Location: 1..83629 Organism: Enterococcus faecium strain VRE-WC072 Replicon: plasmid unnamed2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MKI62_RS14650 (MKI62_002925) | 1..1041 | + | 1041 | WP_000997689.1 | replication initiator protein A | - |
| MKI62_RS14655 (MKI62_002926) | 1657..2337 | - | 681 | WP_002287920.1 | IS6 family transposase IS1216E | Transposase |
| MKI62_RS14660 (MKI62_002927) | 2483..2566 | + | 84 | WP_001814874.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| MKI62_RS14665 (MKI62_002928) | 2691..3428 | + | 738 | WP_001038792.1 | rRNA adenine N-6-methyltransferase | ARG |
| MKI62_RS14670 (MKI62_002929) | 3598..3858 | + | 261 | Protein_4 | topoisomerase DNA-binding C4 zinc finger domain-containing protein | - |
| MKI62_RS14675 (MKI62_002930) | 4021..4686 | + | 666 | Protein_5 | IS1182 family transposase IS1182 | Transposase |
| MKI62_RS14680 (MKI62_002931) | 4722..4967 | + | 246 | WP_000567888.1 | single-stranded DNA-binding protein | - |
| MKI62_RS14685 (MKI62_002932) | 5070..5939 | + | 870 | WP_000228166.1 | nucleotidyltransferase domain-containing protein | - |
| MKI62_RS14690 (MKI62_002933) | 5920..6654 | + | 735 | WP_000662263.1 | class I SAM-dependent methyltransferase | - |
| MKI62_RS14695 (MKI62_002934) | 6687..7595 | + | 909 | WP_001255866.1 | Aminoglycoside 6-adenylyltransferase | ARG |
| MKI62_RS14700 (MKI62_002935) | 7592..8134 | + | 543 | WP_000627290.1 | streptothricin N-acetyltransferase Sat4 | - |
| MKI62_RS14705 (MKI62_002936) | 8227..9021 | + | 795 | WP_001096887.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| MKI62_RS14710 (MKI62_002937) | 9297..9839 | + | 543 | WP_002321977.1 | HTH domain-containing protein | - |
| MKI62_RS14715 (MKI62_002938) | 9869..10549 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| MKI62_RS14720 (MKI62_002939) | 10624..10719 | - | 96 | Protein_14 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| MKI62_RS14725 (MKI62_002940) | 10844..13831 | + | 2988 | WP_000343406.1 | Tn3 family transposase TnBth1 | Transposase |
| MKI62_RS14730 (MKI62_002941) | 13980..14189 | + | 210 | Protein_16 | DNA topoisomerase | - |
| MKI62_RS14735 (MKI62_002942) | 14324..14506 | + | 183 | Protein_17 | IS6 family transposase IS1216E | Transposase |
| MKI62_RS14740 (MKI62_002943) | 14482..14838 | + | 357 | WP_029756604.1 | helix-turn-helix domain-containing protein | - |
| MKI62_RS14745 (MKI62_002944) | 15352..15519 | - | 168 | WP_005228365.1 | cysteine-rich KTR domain-containing protein | - |
| MKI62_RS14750 (MKI62_002945) | 15607..17547 | - | 1941 | WP_002405437.1 | Tetracycline resistance protein TetM from transposon TnFO1 | VF |
| MKI62_RS14755 (MKI62_002947) | 18186..18866 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| MKI62_RS14760 (MKI62_002948) | 18900..20147 | - | 1248 | WP_000913852.1 | hypothetical protein | - |
| MKI62_RS14765 (MKI62_002949) | 20201..20575 | - | 375 | WP_000713874.1 | lactococcin 972 family bacteriocin | - |
| MKI62_RS14770 (MKI62_002950) | 20708..21169 | + | 462 | WP_000389746.1 | ISNCY family transposase ISH7A | Transposase |
| MKI62_RS14775 (MKI62_002951) | 21685..22101 | - | 417 | WP_001232860.1 | hypothetical protein | - |
| MKI62_RS14780 (MKI62_002952) | 22103..22384 | - | 282 | WP_000353845.1 | hypothetical protein | - |
| MKI62_RS14785 (MKI62_002953) | 22531..23211 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| MKI62_RS14790 (MKI62_002954) | 23409..24014 | + | 606 | WP_000599739.1 | Fic family protein | - |
| MKI62_RS14795 (MKI62_002955) | 24030..24602 | + | 573 | WP_000170424.1 | Tn3 family transposase TnpR_ISAzs17 | Transposase |
| MKI62_RS14800 (MKI62_002956) | 25075..25572 | - | 498 | WP_228780308.1 | IS3 family transposase ISBce13 | Transposase |
| MKI62_RS14810 (MKI62_002959) | 27316..27570 | - | 255 | WP_000199136.1 | IS3 family transposase ISBce13 | Transposase |
| MKI62_RS14815 (MKI62_002960) | 27763..28038 | - | 276 | WP_001196543.1 | DNA segregation protein PrgO | - |
| MKI62_RS14820 (MKI62_002961) | 28010..28963 | - | 954 | WP_000429439.1 | ParA family protein | - |
| MKI62_RS14825 (MKI62_002962) | 29575..31068 | + | 1494 | WP_000947691.1 | primase C-terminal domain-containing protein | - |
| MKI62_RS14830 (MKI62_002963) | 31203..31499 | + | 297 | WP_000053907.1 | replication control protein PrgN | - |
| MKI62_RS14835 (MKI62_002964) | 31523..32482 | - | 960 | WP_000222573.1 | IS30 family transposase IS1062 | Transposase |
| MKI62_RS14840 (MKI62_002965) | 32665..33270 | + | 606 | Protein_38 | hypothetical protein | - |
| MKI62_RS14845 (MKI62_002966) | 33345..34025 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| MKI62_RS14850 (MKI62_002967) | 34079..34219 | - | 141 | Protein_40 | glutaredoxin domain-containing protein | - |
| MKI62_RS14855 (MKI62_002968) | 34620..35093 | + | 474 | WP_002287797.1 | hypothetical protein | VF |
| MKI62_RS14860 (MKI62_002969) | 35090..37222 | + | 2133 | WP_002287799.1 | Fe(2+) transporter FeoB | VF |
| MKI62_RS14865 (MKI62_002970) | 37224..37358 | + | 135 | WP_002290587.1 | hypothetical protein | - |
| MKI62_RS14870 (MKI62_002971) | 37452..38096 | + | 645 | WP_002287801.1 | GntR family transcriptional regulator | - |
| MKI62_RS14875 (MKI62_002972) | 38283..39476 | + | 1194 | WP_002287805.1 | Glycine betaine transport ATP-binding protein OpuAA | VF |
| MKI62_RS14880 (MKI62_002973) | 39469..41196 | + | 1728 | WP_002287807.1 | ABC transporter permease/substrate binding protein | - |
| MKI62_RS14885 (MKI62_002974) | 41590..41787 | + | 198 | WP_002304799.1 | class II bacteriocin | - |
| MKI62_RS14890 (MKI62_002975) | 41789..42100 | + | 312 | WP_002287810.1 | bacteriocin immunity protein | - |
| MKI62_RS14895 (MKI62_002976) | 42204..42350 | + | 147 | WP_002321654.1 | EntF family bacteriocin induction factor | - |
| MKI62_RS14900 (MKI62_002977) | 42347..43300 | - | 954 | WP_000222572.1 | IS30 family transposase IS1252 | Transposase |
| MKI62_RS14905 (MKI62_002978) | 43943..44506 | + | 564 | WP_000017403.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| MKI62_RS14910 (MKI62_002979) | 44785..45072 | - | 288 | WP_000312842.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MKI62_RS14915 (MKI62_002980) | 45062..45391 | - | 330 | WP_000629052.1 | hypothetical protein | - |
| MKI62_RS14920 (MKI62_002981) | 45696..46025 | + | 330 | WP_000754864.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| MKI62_RS14925 (MKI62_002982) | 46312..46797 | - | 486 | WP_000516404.1 | glycopeptide resistance protein VanZ-A | - |
| MKI62_RS14930 (MKI62_002983) | 46950..47861 | - | 912 | WP_000732308.1 | VanY-A/VanY-F/VanY-M family D-Ala-D-Ala carboxypeptidase | - |
| MKI62_RS14935 (MKI62_002984) | 48289..48897 | - | 609 | WP_000402348.1 | D-alanyl-D-alanine dipeptidase | ARG |
| MKI62_RS14940 (MKI62_002985) | 48903..49934 | - | 1032 | WP_001079843.1 | Vancomycin/teicoplanin A-type resistance protein VanA | ARG |
| MKI62_RS14945 (MKI62_002986) | 49927..50895 | - | 969 | WP_001059542.1 | D-specific alpha-keto acid dehydrogenase | ARG |
| MKI62_RS14950 (MKI62_002987) | 51227..52519 | + | 1293 | WP_000122610.1 | ISL3 family transposase IS1251 | Transposase |
| MKI62_RS14955 (MKI62_002988) | 52617..53771 | - | 1155 | WP_002305818.1 | VanA-type vancomycin resistance histidine kinase VanS | - |
| MKI62_RS14960 (MKI62_002989) | 53749..54444 | - | 696 | WP_001280781.1 | Transcriptional regulatory protein WalR | VF |
| MKI62_RS14965 (MKI62_002990) | 54658..55134 | - | 477 | WP_029756586.1 | Tn3 family transposase TnpR_ISAzs17 | Transposase |
| MKI62_RS14970 (MKI62_002991) | 55151..55831 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| MKI62_RS14975 (MKI62_002992) | 55879..56370 | + | 492 | Protein_65 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| MKI62_RS14980 (MKI62_002993) | 56415..56582 | - | 168 | WP_000824191.1 | hypothetical protein | - |
| MKI62_RS14985 (MKI62_002994) | 56616..56915 | - | 300 | WP_000366408.1 | BRCT domain-containing protein | - |
| MKI62_RS14990 (MKI62_002995) | 56956..57573 | - | 618 | WP_001224538.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| MKI62_RS14995 (MKI62_002996) | 57898..58284 | - | 387 | WP_000391061.1 | hypothetical protein | - |
| MKI62_RS15000 (MKI62_002997) | 58373..60724 | - | 2352 | WP_000344083.1 | DUF1906 domain-containing protein | - |
| MKI62_RS15005 (MKI62_002998) | 60849..61538 | - | 690 | WP_000718009.1 | hypothetical protein | - |
| MKI62_RS15010 (MKI62_002999) | 61552..62004 | - | 453 | WP_000751236.1 | hypothetical protein | - |
| MKI62_RS15015 (MKI62_003000) | 62135..62813 | + | 679 | Protein_73 | IS6 family transposase IS1216E | Transposase |
| MKI62_RS15020 (MKI62_003001) | 63138..64869 | - | 1732 | Protein_74 | ABC transporter permease/substrate binding protein | - |
| MKI62_RS15025 (MKI62_003002) | 64862..66054 | - | 1193 | Protein_75 | Glycine betaine transport ATP-binding protein OpuAA | VF |
| MKI62_RS15030 (MKI62_003003) | 66241..66887 | - | 647 | Protein_76 | GntR family transcriptional regulator | - |
| MKI62_RS15035 (MKI62_003004) | 66989..67111 | - | 123 | Protein_77 | FeoB-associated Cys-rich membrane protein | - |
| MKI62_RS15040 | 67275..67838 | - | 564 | WP_242425894.1 | Fe(2+) transporter FeoB | VF |
| MKI62_RS15045 | 67892..68752 | - | 861 | WP_242425896.1 | Fe(2+) transporter FeoB | VF |
| MKI62_RS15050 | 68719..68874 | - | 156 | WP_242425897.1 | Fe(2+) transporter FeoB | VF |
| MKI62_RS15055 | 68865..69239 | - | 375 | WP_242425895.1 | Fe(2+) transporter FeoB | VF |
| MKI62_RS15060 (MKI62_003006) | 69236..69709 | - | 474 | WP_002287797.1 | hypothetical protein | VF |
| MKI62_RS15065 (MKI62_003007) | 70108..70248 | + | 141 | Protein_83 | glutaredoxin domain-containing protein | - |
| MKI62_RS15070 (MKI62_003008) | 70303..70983 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| MKI62_RS15075 (MKI62_003009) | 71059..71766 | + | 708 | Protein_85 | replication initiation protein | - |
| MKI62_RS15080 (MKI62_003010) | 71903..72319 | - | 417 | WP_001232859.1 | hypothetical protein | - |
| MKI62_RS15085 (MKI62_003011) | 72322..72606 | - | 285 | WP_000353844.1 | hypothetical protein | - |
| MKI62_RS15090 (MKI62_003012) | 72972..73196 | + | 225 | WP_000410576.1 | hypothetical protein | - |
| MKI62_RS15095 (MKI62_003014) | 74319..74999 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| MKI62_RS15100 (MKI62_003015) | 75075..75641 | + | 567 | Protein_90 | hypothetical protein | - |
| MKI62_RS15105 | 75806..76006 | + | 201 | WP_001033544.1 | 4-hydroxybenzoate octaprenyltransferase | - |
| MKI62_RS15110 (MKI62_003016) | 76022..76201 | + | 180 | WP_001120991.1 | hypothetical protein | - |
| MKI62_RS15115 (MKI62_003017) | 76332..76601 | + | 270 | WP_000388479.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| MKI62_RS15120 (MKI62_003018) | 76594..76851 | + | 258 | WP_000588503.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| MKI62_RS15125 (MKI62_003019) | 77489..78313 | + | 825 | WP_001809248.1 | hypothetical protein | - |
| MKI62_RS15130 (MKI62_003020) | 78478..79092 | - | 615 | WP_001261742.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| MKI62_RS15135 (MKI62_003021) | 79542..80867 | + | 1326 | WP_000969590.1 | Y-family DNA polymerase | - |
| MKI62_RS15140 (MKI62_003022) | 80860..81210 | + | 351 | WP_000568378.1 | hypothetical protein | - |
| MKI62_RS15145 (MKI62_003023) | 81207..81386 | + | 180 | WP_001021554.1 | hypothetical protein | - |
| MKI62_RS15150 (MKI62_003024) | 81522..81812 | + | 291 | WP_000026576.1 | hypothetical protein | - |
| MKI62_RS15155 (MKI62_003025) | 82180..82968 | + | 789 | WP_000101106.1 | Sporulation initiation inhibitor protein Soj | VF |
| MKI62_RS15160 (MKI62_003026) | 82955..83281 | + | 327 | WP_000796719.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|