MGE detailed information
MGE type: Conjugative plasmid MGE length: 171032 bp
Accession: NZ_CP091848 Location: 1..171032 Organism: Klebsiella pneumoniae strain NB05 Replicon: plasmid pNB05-2
Accession: NZ_CP091848 Location: 1..171032 Organism: Klebsiella pneumoniae strain NB05 Replicon: plasmid pNB05-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L7D54_RS27770 | 1..1011 | + | 1011 | WP_004152063.1 | RepB family plasmid replication initiator protein | - |
| L7D54_RS27775 | 1728..2468 | - | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| L7D54_RS27780 | 3612..4559 | + | 948 | WP_004152065.1 | sensor domain-containing diguanylate cyclase | - |
| L7D54_RS27785 | 4586..4897 | - | 312 | WP_071527918.1 | EAL domain-containing protein | - |
| L7D54_RS27790 | 4917..5885 | + | 969 | WP_013815099.1 | IS5 family transposase IS903B | Transposase |
| L7D54_RS27795 | 6558..6815 | - | 258 | WP_004197688.1 | hypothetical protein | - |
| L7D54_RS27800 | 7456..7971 | + | 516 | Protein_6 | hypothetical protein | VF |
| L7D54_RS27805 | 8035..8871 | + | 837 | WP_004152068.1 | hypothetical protein | VF |
| L7D54_RS27810 | 9854..11131 | - | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| L7D54_RS27815 | 11194..13191 | - | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| L7D54_RS27830 | 15529..16013 | + | 485 | Protein_12 | IS1 family transposase IS1X2 | Transposase |
| L7D54_RS27835 | 16029..16571 | + | 543 | Protein_13 | ISL3 family transposase ISKpn25 | Transposase |
| L7D54_RS27840 | 16867..17298 | - | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| L7D54_RS27845 | 17549..19024 | - | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| L7D54_RS27850 | 19017..19697 | - | 681 | WP_001572351.1 | Regulator of RpoS | VF |
| L7D54_RS27855 | 19887..21272 | + | 1386 | WP_238050199.1 | hypothetical protein | VF |
| L7D54_RS27860 | 21301..21654 | + | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| L7D54_RS27865 | 21768..23060 | + | 1293 | WP_004152079.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| L7D54_RS27870 | 23071..26217 | + | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| L7D54_RS27875 | 26304..26744 | + | 441 | WP_000758228.1 | DUF411 domain-containing protein | - |
| L7D54_RS27880 | 26871..29318 | + | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| L7D54_RS27885 | 29359..29556 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| L7D54_RS27890 | 29590..30327 | - | 738 | WP_004118669.1 | hypothetical protein | VF |
| L7D54_RS27895 | 30616..31065 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| L7D54_RS27900 | 31354..32334 | - | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| L7D54_RS27905 | 32499..34316 | + | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| L7D54_RS27910 | 34322..35212 | + | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| L7D54_RS27915 | 35252..35632 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| L7D54_RS27920 | 35637..36566 | + | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| L7D54_RS27925 | 36621..37301 | + | 681 | WP_001188930.1 | Regulator of RpoS | VF |
| L7D54_RS27930 | 37298..38698 | + | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| L7D54_RS27935 | 38915..39349 | + | 435 | WP_004152085.1 | copper resistance system metallochaperone PcoE | - |
| L7D54_RS27940 | 39581..39760 | - | 180 | WP_004152086.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| L7D54_RS27945 | 39821..41441 | - | 1621 | Protein_35 | ISL3 family transposase ISEc38 | Transposase |
| L7D54_RS27950 | 41503..42012 | + | 510 | WP_031944101.1 | aquaporin | - |
| L7D54_RS27955 | 42062..42559 | - | 498 | WP_004152091.1 | GNAT family N-acetyltransferase | - |
| L7D54_RS27960 | 42891..43217 | + | 327 | WP_004152092.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| L7D54_RS27965 | 43214..43927 | + | 714 | WP_004152093.1 | arsenical resistance protein ArsH | - |
| L7D54_RS27970 | 43936..44481 | + | 546 | WP_004182005.1 | sigma-70 family RNA polymerase sigma factor | - |
| L7D54_RS27975 | 44557..44919 | + | 363 | WP_004152095.1 | arsenic metallochaperone ArsD family protein | - |
| L7D54_RS27980 | 44944..46694 | + | 1751 | Protein_42 | arsenical pump-driving ATPase | - |
| L7D54_RS27985 | 46816..47352 | + | 537 | WP_004152096.1 | GNAT family N-acetyltransferase | - |
| L7D54_RS27990 | 47385..47810 | - | 426 | WP_004152097.1 | glutaredoxin-dependent arsenate reductase | - |
| L7D54_RS27995 | 47823..49112 | - | 1290 | WP_004152098.1 | arsenite efflux transporter membrane subunit ArsB | - |
| L7D54_RS28000 | 49160..50911 | - | 1752 | WP_004152099.1 | Iron-sulfur cluster carrier protein | VF |
| L7D54_RS28005 | 50929..51291 | - | 363 | WP_004152100.1 | arsenite efflux transporter metallochaperone ArsD | - |
| L7D54_RS28010 | 51341..51691 | - | 351 | WP_004152101.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| L7D54_RS28015 | 52049..52318 | + | 270 | WP_004152102.1 | hypothetical protein | - |
| L7D54_RS28020 | 52306..52881 | + | 576 | WP_004152103.1 | hypothetical protein | - |
| L7D54_RS28025 | 52912..53406 | + | 495 | WP_004152104.1 | DNA-binding protein | - |
| L7D54_RS28030 | 53450..53818 | + | 369 | WP_004152105.1 | hypothetical protein | - |
| L7D54_RS28035 | 53852..54055 | + | 204 | WP_004152106.1 | HHA domain-containing protein | - |
| L7D54_RS28040 | 54104..54361 | + | 258 | WP_004152107.1 | hypothetical protein | - |
| L7D54_RS28045 | 54437..54691 | + | 255 | WP_004152108.1 | hypothetical protein | - |
| L7D54_RS28050 | 54867..55133 | + | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| L7D54_RS28055 | 55121..55603 | + | 483 | WP_003026803.1 | GNAT family N-acetyltransferase | Toxin Detail |
| L7D54_RS28060 | 55804..57207 | + | 1404 | WP_001567368.1 | ISNCY family transposase ISKpn21 | Transposase |
| L7D54_RS28065 | 57236..57868 | - | 633 | WP_001567369.1 | hypothetical protein | - |
| L7D54_RS28070 | 58098..59444 | + | 1347 | WP_238050200.1 | ISNCY family transposase ISLad2 | Transposase |
| L7D54_RS29195 | 59605..59736 | + | 132 | WP_004218042.1 | hypothetical protein | - |
| L7D54_RS28075 | 59945..61110 | - | 1166 | Protein_62 | IS3 family transposase ISKpn38 | Transposase |
| L7D54_RS28080 | 61287..62249 | - | 963 | WP_004152113.1 | zinc metalloprotease HtpX | - |
| L7D54_RS28085 | 62236..62724 | - | 489 | WP_004152114.1 | phosphate-starvation-inducible PsiE family protein | - |
| L7D54_RS28090 | 62839..62985 | - | 147 | Protein_65 | diguanylate cyclase | - |
| L7D54_RS28095 | 63223..63420 | - | 198 | WP_004152115.1 | hypothetical protein | - |
| L7D54_RS28100 | 63420..66215 | - | 2796 | WP_004152116.1 | ATP-dependent Clp protease ATP-binding subunit ClpX | VF |
| L7D54_RS28105 | 66330..66899 | - | 570 | WP_004152117.1 | Small heat shock protein IbpA | VF |
| L7D54_RS28110 | 66934..67215 | - | 282 | WP_004152118.1 | helix-turn-helix domain-containing protein | - |
| L7D54_RS28115 | 67459..67722 | - | 264 | WP_004118208.1 | hypothetical protein | - |
| L7D54_RS28120 | 67737..68000 | + | 264 | WP_004118209.1 | transposase | - |
| L7D54_RS28125 | 67945..68061 | + | 117 | Protein_72 | transposase domain-containing protein | - |
| L7D54_RS28130 | 68246..68943 | + | 698 | WP_223174644.1 | IS1 family transposase IS1X2 | Transposase |
| L7D54_RS28135 | 69202..70182 | + | 981 | WP_000019473.1 | IS5 family transposase ISKpn26 | Transposase |
| L7D54_RS28140 | 70764..71283 | - | 520 | Protein_75 | IS5 family transposase ISPst7 | Transposase |
| L7D54_RS28145 | 71391..72260 | - | 870 | WP_004152692.1 | HTH-type transcriptional regulator ArgP | VF |
| L7D54_RS28150 | 72254..73264 | - | 1011 | WP_004152693.1 | phosphonate dehydrogenase PtxD | - |
| L7D54_RS28155 | 73273..74100 | - | 828 | WP_004152694.1 | phosphonate ABC transporter, permease protein PhnE | - |
| L7D54_RS28160 | 74109..74972 | - | 864 | WP_004152695.1 | phosphate/phosphite/phosphonate ABC transporter substrate-binding protein | - |
| L7D54_RS28165 | 74969..75796 | - | 828 | WP_004153729.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| L7D54_RS28170 | 76138..76446 | + | 309 | Protein_81 | IS5 family transposase ISThi1 | Transposase |
| L7D54_RS28175 | 76652..77356 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| L7D54_RS28180 | 77347..78612 | + | 1266 | WP_004198116.1 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| L7D54_RS28185 | 78691..79695 | + | 1005 | WP_000427623.1 | IS110 family transposase IS4321R | Transposase |
| L7D54_RS28190 | 79987..80655 | + | 669 | WP_044117068.1 | IS6 family transposase IS26 | Transposase |
| L7D54_RS28195 | 80845..81660 | - | 816 | WP_000018329.1 | hypothetical protein | ARG |
| L7D54_RS28200 | 81811..82515 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| L7D54_RS28205 | 82637..83542 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| L7D54_RS28210 | 83539..84778 | + | 1240 | Protein_89 | macrolide resistance MFS transporter Mrx(A) | - |
| L7D54_RS28215 | 84778..85362 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| L7D54_RS28220 | 85855..86619 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| L7D54_RS28225 | 86789..87493 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| L7D54_RS28230 | 87559..89073 | + | 1515 | Protein_93 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| L7D54_RS28235 | 89106..90164 | + | 1059 | Protein_94 | lactose permease | - |
| L7D54_RS28240 | 90256..91224 | + | 969 | WP_160559306.1 | IS5 family transposase IS903B | Transposase |
| L7D54_RS28245 | 91869..94178 | + | 2310 | WP_004152290.1 | TerB N-terminal domain-containing protein | - |
| L7D54_RS28250 | 94182..95498 | + | 1317 | WP_004152291.1 | ATP-binding protein | - |
| L7D54_RS28255 | 95495..97690 | + | 2196 | WP_000093087.1 | DEAD/DEAH box helicase | - |
| L7D54_RS28260 | 99137..99994 | - | 858 | WP_004152292.1 | incFII family plasmid replication initiator RepA | - |
| L7D54_RS28265 | 100281..100559 | - | 279 | WP_004199332.1 | replication regulatory protein RepA | - |
| L7D54_RS28270 | 100880..101431 | - | 552 | WP_004152294.1 | Cardiolipin synthase B | VF |
| L7D54_RS28275 | 101536..101616 | - | 81 | Protein_102 | hypothetical protein | - |
| L7D54_RS28280 | 101700..101978 | - | 279 | WP_004152296.1 | bacteriocin immunity protein | - |
| L7D54_RS28285 | 101980..104301 | - | 2322 | WP_004178051.1 | klebicin B-related nuclease bacteriocin | - |
| L7D54_RS28290 | 104658..105203 | + | 546 | WP_004178052.1 | hypothetical protein | - |
| L7D54_RS28295 | 105418..105765 | - | 348 | WP_004152301.1 | DUF6404 family protein | - |
| L7D54_RS28300 | 105785..106381 | - | 597 | WP_004178053.1 | fertility inhibition protein FinO | - |
| L7D54_RS28305 | 106539..107264 | - | 726 | WP_004152303.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| L7D54_RS28310 | 107344..112605 | - | 5262 | WP_004153029.1 | ATP-dependent RecD-like DNA helicase | Relaxase |
| L7D54_RS28315 | 112605..114914 | - | 2310 | WP_004152630.1 | type IV conjugative transfer system coupling protein TraD | - |
| L7D54_RS28320 | 115274..116005 | - | 732 | WP_004152629.1 | conjugal transfer complement resistance protein TraT | - |
| L7D54_RS28325 | 116195..116722 | - | 528 | WP_004153030.1 | hypothetical protein | - |
| L7D54_RS28330 | 116866..117563 | + | 698 | WP_103215986.1 | IS1 family transposase IS1R | Transposase |
| L7D54_RS28335 | 117574..120354 | - | 2781 | WP_137922717.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| L7D54_RS28340 | 120354..121724 | - | 1371 | WP_004178055.1 | conjugal transfer pilus assembly protein TraH | - |
| L7D54_RS28345 | 121711..122139 | - | 429 | WP_004152689.1 | hypothetical protein | - |
| L7D54_RS28350 | 122132..122704 | - | 573 | WP_004152688.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| L7D54_RS28355 | 122676..122915 | - | 240 | WP_004152687.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| L7D54_RS28360 | 122926..123678 | - | 753 | WP_004152686.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| L7D54_RS28365 | 123699..124025 | - | 327 | WP_004152685.1 | hypothetical protein | - |
| L7D54_RS28370 | 124253..124489 | - | 237 | WP_004152683.1 | conjugal transfer protein TrbE | - |
| L7D54_RS28375 | 124521..126476 | - | 1956 | WP_004153093.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| L7D54_RS28380 | 126524..127162 | - | 639 | WP_004152682.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| L7D54_RS28385 | 127175..128134 | - | 960 | WP_015065634.1 | conjugal transfer pilus assembly protein TraU | - |
| L7D54_RS28390 | 128178..128804 | - | 627 | WP_004152590.1 | type-F conjugative transfer system protein TraW | - |
| L7D54_RS28395 | 128804..129193 | - | 390 | WP_004152591.1 | type-F conjugative transfer system protein TrbI | - |
| L7D54_RS28400 | 129193..131832 | - | 2640 | WP_004152592.1 | type IV secretion system protein TraC | - |
| L7D54_RS28405 | 131904..132302 | - | 399 | WP_004153071.1 | hypothetical protein | - |
| L7D54_RS28410 | 132598..133002 | - | 405 | WP_004152594.1 | hypothetical protein | - |
| L7D54_RS28415 | 133069..133386 | - | 318 | WP_004152595.1 | hypothetical protein | - |
| L7D54_RS28420 | 133387..133605 | - | 219 | WP_004171484.1 | hypothetical protein | - |
| L7D54_RS28425 | 133629..133919 | - | 291 | WP_004152596.1 | hypothetical protein | - |
| L7D54_RS28430 | 133924..134334 | - | 411 | WP_004152597.1 | lipase chaperone | - |
| L7D54_RS28435 | 134466..135035 | - | 570 | WP_004152598.1 | type IV conjugative transfer system lipoprotein TraV | - |
| L7D54_RS28440 | 135058..135654 | - | 597 | WP_004152599.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| L7D54_RS28445 | 135647..137072 | - | 1426 | Protein_136 | conjugal transfer protein TraB | - |
| L7D54_RS28450 | 137072..137812 | - | 741 | WP_004152601.1 | type-F conjugative transfer system secretin TraK | - |
| L7D54_RS28455 | 137799..138365 | - | 567 | WP_004152602.1 | type IV conjugative transfer system protein TraE | - |
| L7D54_RS28460 | 138385..138690 | - | 306 | WP_004178059.1 | type IV conjugative transfer system protein TraL | - |
| L7D54_RS28465 | 138704..139072 | - | 369 | WP_004178060.1 | type IV conjugative transfer system pilin TraA | - |
| L7D54_RS28470 | 139126..139497 | - | 372 | WP_004208838.1 | TraY domain-containing protein | - |
| L7D54_RS28475 | 139581..140276 | - | 696 | WP_004178061.1 | transcriptional regulator TraJ family protein | - |
| L7D54_RS28480 | 140490..140645 | - | 156 | Protein_143 | conjugal transfer protein TraM | - |
| L7D54_RS28485 | 140681..141649 | + | 969 | WP_072198477.1 | IS5 family transposase IS903B | Transposase |
| L7D54_RS28490 | 141711..141953 | - | 243 | Protein_145 | relaxosome protein TraM | - |
| L7D54_RS28495 | 142381..142866 | + | 486 | WP_004178063.1 | hypothetical protein | VF |
| L7D54_RS28500 | 142899..143228 | - | 330 | WP_011977736.1 | DUF5983 family protein | - |
| L7D54_RS28505 | 143261..144082 | - | 822 | WP_004178064.1 | DUF932 domain-containing protein | - |
| L7D54_RS28510 | 144916..145329 | - | 414 | WP_004152722.1 | helix-turn-helix domain-containing protein | - |
| L7D54_RS28515 | 145330..145608 | - | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| L7D54_RS28520 | 145598..145918 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| L7D54_RS28525 | 145999..146223 | - | 225 | WP_004152719.1 | hypothetical protein | - |
| L7D54_RS28530 | 146234..146446 | - | 213 | WP_004152718.1 | hypothetical protein | - |
| L7D54_RS28535 | 146507..146863 | - | 357 | WP_004152717.1 | hypothetical protein | - |
| L7D54_RS28540 | 147499..147849 | - | 351 | WP_137922726.1 | hypothetical protein | - |
| L7D54_RS28545 | 147846..148118 | - | 273 | WP_004152759.1 | hypothetical protein | - |
| L7D54_RS28550 | 148818..148979 | - | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| L7D54_RS28555 | 149051..150130 | + | 1080 | WP_004220208.1 | IS481 family transposase ISKpn28 | Transposase |
| L7D54_RS28560 | 150308..150682 | - | 375 | WP_004152638.1 | hypothetical protein | - |
| L7D54_RS28565 | 150738..151064 | - | 327 | WP_004152639.1 | hypothetical protein | - |
| L7D54_RS28570 | 151061..151789 | - | 729 | WP_004152640.1 | plasmid SOS inhibition protein A | - |
| L7D54_RS28575 | 151786..152217 | - | 432 | WP_004152641.1 | conjugation system SOS inhibitor PsiB | - |
| L7D54_RS28580 | 152262..154320 | - | 2059 | Protein_163 | ParB/RepB/Spo0J family partition protein | - |
| L7D54_RS28585 | 154390..154638 | - | 249 | WP_004152643.1 | DUF905 domain-containing protein | - |
| L7D54_RS28590 | 154687..155229 | - | 543 | WP_004152644.1 | single-stranded DNA-binding protein | - |
| L7D54_RS28595 | 156005..156568 | - | 564 | WP_004152645.1 | methyltransferase | - |
| L7D54_RS28600 | 156616..157971 | - | 1356 | WP_004178068.1 | DUF3560 domain-containing protein | - |
| L7D54_RS28605 | 158023..158253 | - | 231 | WP_004198570.1 | hypothetical protein | - |
| L7D54_RS28610 | 158345..158572 | - | 228 | WP_004178072.1 | hypothetical protein | - |
| L7D54_RS28615 | 159353..159670 | - | 318 | WP_004118473.1 | hypothetical protein | - |
| L7D54_RS28620 | 159705..159959 | - | 255 | WP_004152754.1 | DNA polymerase III subunit theta | - |
| L7D54_RS28625 | 160196..160621 | - | 426 | WP_004118478.1 | antirestriction protein | - |
| L7D54_RS28630 | 161142..161372 | - | 231 | WP_004152753.1 | hypothetical protein | - |
| L7D54_RS28635 | 161606..163093 | - | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| L7D54_RS28640 | 163496..163921 | + | 426 | WP_004178083.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| L7D54_RS28645 | 163921..165192 | + | 1272 | WP_004152715.1 | Y-family DNA polymerase | - |
| L7D54_RS28650 | 165331..165486 | + | 156 | WP_001776126.1 | hypothetical protein | - |
| L7D54_RS28655 | 165509..166707 | - | 1199 | Protein_178 | IS200-IS605 family transposase IS609 | Transposase |
| L7D54_RS28660 | 168144..169115 | - | 972 | WP_004152062.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| L7D54_RS28665 | 169115..170281 | - | 1167 | WP_000523813.1 | hypothetical protein | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|