MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 153835 bp
Accession: NZ_CP090887 Location: 885037..1038871 Organism: Streptococcus pneumoniae strain NP7536 Replicon: chromosome
Accession: NZ_CP090887 Location: 885037..1038871 Organism: Streptococcus pneumoniae strain NP7536 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L1A18_RS04410 (L1A18_04410) | 880591..881814 | - | 1224 | WP_000222059.1 | peptidase T | - |
| L1A18_RS04415 (L1A18_04415) | 881968..883062 | + | 1095 | WP_000709226.1 | ferrochelatase | - |
| L1A18_RS04420 (L1A18_04420) | 883104..883481 | - | 378 | WP_000916795.1 | large conductance mechanosensitive channel protein MscL | - |
| L1A18_RS04425 (L1A18_04425) | 883563..883994 | - | 432 | WP_000742997.1 | GtrA family protein | - |
| L1A18_RS04430 (L1A18_04430) | 884117..884626 | + | 510 | WP_000737071.1 | QueT transporter family protein | - |
| L1A18_RS04440 (L1A18_04440) | 885140..886216 | + | 1077 | WP_000542477.1 | aspartate-semialdehyde dehydrogenase | - |
| L1A18_RS04445 (L1A18_04445) | 886272..887207 | + | 936 | WP_000121619.1 | 4-hydroxy-tetrahydrodipicolinate synthase | - |
| L1A18_RS04450 (L1A18_04450) | 887254..888627 | - | 1374 | WP_000632719.1 | tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE | - |
| L1A18_RS04455 (L1A18_04455) | 888764..888946 | - | 183 | WP_001117401.1 | 4-oxalocrotonate tautomerase | - |
| L1A18_RS04460 (L1A18_04460) | 889069..889659 | + | 591 | WP_000068139.1 | thymidine kinase | - |
| L1A18_RS04465 (L1A18_04465) | 889656..890735 | + | 1080 | WP_001028796.1 | peptide chain release factor 1 | - |
| L1A18_RS04470 (L1A18_04470) | 890735..891574 | + | 840 | WP_000761897.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| L1A18_RS04475 (L1A18_04475) | 891561..892160 | + | 600 | WP_001809176.1 | L-threonylcarbamoyladenylate synthase | - |
| L1A18_RS04480 (L1A18_04480) | 892162..892593 | + | 432 | WP_000942936.1 | GNAT family N-acetyltransferase | - |
| L1A18_RS04485 (L1A18_04485) | 892655..893911 | + | 1257 | WP_000575521.1 | serine hydroxymethyltransferase | - |
| L1A18_RS04490 (L1A18_04490) | 893919..894893 | + | 975 | WP_000356126.1 | nucleoid-associated protein | - |
| L1A18_RS04495 (L1A18_04495) | 894893..895507 | + | 615 | WP_000476372.1 | cell wall hydrolase Pmp23 | - |
| L1A18_RS04500 (L1A18_04500) | 895581..896555 | + | 975 | WP_001227738.1 | DUF1002 domain-containing protein | - |
| L1A18_RS04505 (L1A18_04505) | 896629..898261 | + | 1633 | Protein_894 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD | - |
| L1A18_RS04510 (L1A18_04510) | 898475..898753 | + | 279 | WP_000710807.1 | hypothetical protein | - |
| L1A18_RS04515 (L1A18_04515) | 898999..899217 | + | 219 | WP_001207345.1 | helix-turn-helix transcriptional regulator | - |
| L1A18_RS04520 (L1A18_04520) | 899610..900635 | + | 1026 | WP_000790743.1 | ABC transporter substrate-binding protein | - |
| L1A18_RS04525 (L1A18_04525) | 900625..901632 | + | 1008 | WP_001244693.1 | iron ABC transporter permease | - |
| L1A18_RS04530 (L1A18_04530) | 901632..902639 | + | 1008 | WP_001180357.1 | iron ABC transporter permease | - |
| L1A18_RS04535 (L1A18_04535) | 902639..903433 | + | 795 | WP_000677518.1 | ABC transporter ATP-binding protein | - |
| L1A18_RS04540 (L1A18_04540) | 903584..903768 | + | 185 | Protein_901 | IS3 family transposase | - |
| L1A18_RS04545 (L1A18_04545) | 903887..904210 | + | 324 | WP_229294054.1 | restriction endonuclease subunit S | - |
| L1A18_RS04550 (L1A18_04550) | 904191..904490 | + | 300 | Protein_903 | hypothetical protein | - |
| L1A18_RS04555 (L1A18_04555) | 905175..905336 | + | 162 | WP_000368174.1 | hypothetical protein | - |
| L1A18_RS04560 (L1A18_04560) | 905428..907106 | + | 1679 | Protein_905 | recombinase family protein | - |
| L1A18_RS04565 (L1A18_04565) | 907374..907940 | + | 567 | WP_000234983.1 | hypothetical protein | - |
| L1A18_RS04570 (L1A18_04570) | 908262..908450 | + | 189 | WP_000179769.1 | hypothetical protein | - |
| L1A18_RS04575 (L1A18_04575) | 908512..909270 | + | 759 | WP_000262016.1 | ATP-grasp domain-containing protein | - |
| L1A18_RS04580 (L1A18_04580) | 909328..910182 | + | 855 | WP_000900019.1 | ADP-ribosylglycohydrolase family protein | - |
| L1A18_RS04585 (L1A18_04585) | 910294..911178 | + | 885 | WP_000710115.1 | diacylglycerol kinase family lipid kinase | - |
| L1A18_RS04590 (L1A18_04590) | 911341..913080 | + | 1740 | WP_000423464.1 | glycoside hydrolase family 13 protein | - |
| L1A18_RS04595 (L1A18_04595) | 913355..913810 | + | 456 | WP_000500478.1 | hypothetical protein | - |
| L1A18_RS04600 (L1A18_04600) | 914255..914731 | + | 477 | WP_000579602.1 | type II toxin-antitoxin system antitoxin PezA | Antitoxin Detail |
| L1A18_RS04605 (L1A18_04605) | 914731..915492 | + | 762 | WP_000405368.1 | type II toxin-antitoxin system toxin PezT | Toxin Detail |
| L1A18_RS04610 (L1A18_04610) | 915520..916677 | + | 1158 | WP_001213951.1 | hypothetical protein | - |
| L1A18_RS04615 (L1A18_04615) | 917509..917868 | + | 360 | WP_000529545.1 | SAG1252 family conjugative relaxosome accessory protein | - |
| L1A18_RS04620 (L1A18_04620) | 917878..918243 | + | 366 | WP_000263039.1 | plasmid mobilization relaxosome protein MobC | - |
| L1A18_RS04625 (L1A18_04625) | 918230..920080 | + | 1851 | Protein_918 | SAG1250 family conjugative relaxase | - |
| L1A18_RS04630 (L1A18_04630) | 920388..921353 | + | 966 | WP_000974692.1 | D-alanine--D-alanine ligase | - |
| L1A18_RS04635 (L1A18_04635) | 921419..922627 | + | 1209 | WP_000691719.1 | enolase | - |
| L1A18_RS04640 (L1A18_04640) | 922620..923513 | + | 894 | WP_000368610.1 | aminotransferase class IV | - |
| L1A18_RS04645 (L1A18_04645) | 923510..924322 | + | 813 | WP_000588707.1 | 1-deoxy-D-xylulose-5-phosphate synthase N-terminal domain-containing protein | - |
| L1A18_RS04650 (L1A18_04650) | 924319..925236 | + | 918 | WP_001232538.1 | serine hydroxymethyltransferase | - |
| L1A18_RS04655 (L1A18_04655) | 925202..926410 | + | 1209 | WP_000282560.1 | aminotransferase class III-fold pyridoxal phosphate-dependent enzyme | - |
| L1A18_RS04660 (L1A18_04660) | 926400..927194 | + | 795 | WP_000351847.1 | nucleoside-diphosphate kinase | - |
| L1A18_RS04665 (L1A18_04665) | 927197..928381 | + | 1185 | WP_000239146.1 | histone-lysine N-methyltransferase | - |
| L1A18_RS04670 (L1A18_04670) | 928341..929702 | + | 1362 | WP_000932706.1 | hypothetical protein | - |
| L1A18_RS04675 (L1A18_04675) | 929761..930636 | + | 876 | WP_001809188.1 | isocitrate lyase/phosphoenolpyruvate mutase family protein | - |
| L1A18_RS04680 (L1A18_04680) | 930626..931723 | + | 1098 | WP_000836759.1 | thiamine pyrophosphate-dependent enzyme | - |
| L1A18_RS04685 (L1A18_04685) | 931725..932516 | + | 792 | WP_001809189.1 | seryl-tRNA synthetase | - |
| L1A18_RS04690 (L1A18_04690) | 932516..933565 | + | 1050 | WP_001231248.1 | nucleotidyltransferase family protein | - |
| L1A18_RS04695 (L1A18_04695) | 933692..933931 | + | 240 | WP_000872900.1 | phosphopantetheine-binding protein | - |
| L1A18_RS04700 (L1A18_04700) | 934168..935538 | + | 1371 | WP_224782086.1 | hypothetical protein | - |
| L1A18_RS04705 (L1A18_04705) | 935945..936937 | + | 993 | WP_001240822.1 | ATP-binding cassette domain-containing protein | - |
| L1A18_RS04710 (L1A18_04710) | 936939..937757 | + | 819 | WP_000240144.1 | ABC-2 family transporter protein | - |
| L1A18_RS04715 (L1A18_04715) | 937759..938543 | + | 785 | Protein_936 | ABC transporter permease | - |
| L1A18_RS04720 (L1A18_04720) | 938605..939642 | + | 1038 | Protein_937 | family 1 glycosylhydrolase | - |
| L1A18_RS04725 (L1A18_04725) | 939758..940636 | + | 879 | Protein_938 | aldose 1-epimerase family protein | - |
| L1A18_RS04730 (L1A18_04730) | 940884..941108 | + | 225 | WP_000284846.1 | helix-turn-helix transcriptional regulator | - |
| L1A18_RS04735 (L1A18_04735) | 941513..943285 | + | 1773 | Protein_940 | recombinase family protein | - |
| L1A18_RS04740 (L1A18_04740) | 943369..943977 | + | 609 | WP_000662936.1 | Type 1 glutamine amidotransferase-like domain-containing protein | - |
| L1A18_RS04745 (L1A18_04745) | 944084..944488 | + | 405 | Protein_942 | phosphotransferase | - |
| L1A18_RS04750 (L1A18_04750) | 944611..944921 | + | 311 | Protein_943 | transposase family protein | - |
| L1A18_RS04755 (L1A18_04755) | 945065..946294 | + | 1230 | WP_000703361.1 | FtsW/RodA/SpoVE family cell cycle protein | - |
| L1A18_RS04760 (L1A18_04760) | 946314..949010 | + | 2697 | WP_000058181.1 | phosphoenolpyruvate carboxylase | - |
| L1A18_RS04765 (L1A18_04765) | 949423..950427 | + | 1005 | WP_000792164.1 | tryptophan ABC transporter substrate-binding protein | - |
| L1A18_RS04770 (L1A18_04770) | 950496..951362 | + | 867 | WP_000637242.1 | ABC transporter permease | - |
| L1A18_RS04775 (L1A18_04775) | 951359..952117 | + | 759 | WP_000125408.1 | ABC transporter ATP-binding protein | - |
| L1A18_RS04780 (L1A18_04780) | 952207..953967 | + | 1761 | WP_000227903.1 | DNA primase | - |
| L1A18_RS04785 (L1A18_04785) | 953970..955079 | + | 1110 | WP_000201898.1 | RNA polymerase sigma factor RpoD | - |
| L1A18_RS04790 (L1A18_04790) | 955093..955422 | + | 330 | WP_000331928.1 | metal-sulfur cluster assembly factor | - |
| L1A18_RS04795 (L1A18_04795) | 955537..956580 | + | 1044 | WP_000412279.1 | alpha-galactosylglucosyldiacylglycerol synthase | - |
| L1A18_RS04800 (L1A18_04800) | 956596..957921 | + | 1326 | WP_001219427.1 | glycosyltransferase family 4 protein | - |
| L1A18_RS04805 (L1A18_04805) | 957952..958128 | + | 177 | WP_001256250.1 | PspC domain-containing protein | - |
| L1A18_RS04810 (L1A18_04810) | 958187..958321 | + | 135 | WP_000863859.1 | DUF4044 domain-containing protein | - |
| L1A18_RS04815 (L1A18_04815) | 958385..959695 | + | 1311 | WP_000061642.1 | GTPase ObgE | - |
| L1A18_RS04820 (L1A18_04820) | 959705..959863 | + | 159 | WP_001808548.1 | hypothetical protein | - |
| L1A18_RS10640 | 960738..960863 | - | 126 | WP_001818214.1 | hypothetical protein | - |
| L1A18_RS04825 (L1A18_04825) | 961006..962265 | + | 1260 | WP_001227083.1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | - |
| L1A18_RS04830 (L1A18_04830) | 962281..962832 | + | 552 | WP_001028733.1 | GNAT family N-acetyltransferase | - |
| L1A18_RS04835 (L1A18_04835) | 962825..964102 | + | 1278 | WP_000033830.1 | CBS-HotDog domain-containing transcription factor SpxR | - |
| L1A18_RS04840 (L1A18_04840) | 964118..964978 | + | 861 | WP_000631543.1 | methionyl aminopeptidase | - |
| L1A18_RS04845 (L1A18_04845) | 965359..966163 | + | 805 | WP_078462999.1 | IS5 family transposase | - |
| L1A18_RS04850 (L1A18_04850) | 966354..968645 | + | 2292 | WP_000992861.1 | DNA helicase PcrA | - |
| L1A18_RS04855 (L1A18_04855) | 968688..969368 | + | 681 | WP_000286922.1 | DNA repair protein RadC | - |
| L1A18_RS04860 (L1A18_04860) | 969365..970054 | - | 690 | WP_000743330.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| L1A18_RS04865 (L1A18_04865) | 970072..970713 | - | 642 | WP_000653403.1 | redox-sensing transcriptional repressor Rex | - |
| L1A18_RS04870 (L1A18_04870) | 970796..971011 | - | 216 | WP_000462487.1 | DUF4649 family protein | - |
| L1A18_RS04875 (L1A18_04875) | 971019..971366 | - | 348 | WP_000863509.1 | DUF1831 domain-containing protein | - |
| L1A18_RS04880 (L1A18_04880) | 971371..972486 | - | 1116 | WP_000639664.1 | cysteine desulfurase family protein | - |
| L1A18_RS04885 (L1A18_04885) | 972496..973455 | - | 960 | WP_001283813.1 | ribose-phosphate diphosphokinase | - |
| L1A18_RS04890 (L1A18_04890) | 973568..974137 | - | 570 | WP_000681293.1 | CYTH domain-containing protein | - |
| L1A18_RS04895 (L1A18_04895) | 974265..974936 | + | 672 | WP_000171676.1 | GTP pyrophosphokinase family protein | - |
| L1A18_RS04900 (L1A18_04900) | 974920..975738 | + | 819 | WP_000799053.1 | NAD kinase | - |
| L1A18_RS04905 (L1A18_04905) | 975735..976631 | + | 897 | WP_001210010.1 | RluA family pseudouridine synthase | - |
| L1A18_RS04910 (L1A18_04910) | 976675..977649 | + | 975 | WP_000451584.1 | phosphate acetyltransferase | - |
| L1A18_RS04915 (L1A18_04915) | 977965..978978 | - | 1014 | Protein_977 | transposase | - |
| L1A18_RS04920 (L1A18_04920) | 979198..979497 | - | 300 | WP_000981526.1 | YbaB/EbfC family nucleoid-associated protein | - |
| L1A18_RS04925 (L1A18_04925) | 979989..980567 | + | 579 | WP_000340332.1 | YoaK family protein | - |
| L1A18_RS04930 (L1A18_04930) | 980599..981552 | - | 954 | WP_001155321.1 | IS30-like element ISSpn8 family transposase | - |
| L1A18_RS04935 (L1A18_04935) | 982031..982345 | + | 315 | WP_000109138.1 | 50S ribosomal protein L21 | - |
| L1A18_RS04940 (L1A18_04940) | 982361..982705 | + | 345 | WP_000613699.1 | ribosomal-processing cysteine protease Prp | - |
| L1A18_RS04945 (L1A18_04945) | 982722..983015 | + | 294 | WP_000916509.1 | 50S ribosomal protein L27 | - |
| L1A18_RS04950 (L1A18_04950) | 983361..983531 | - | 171 | WP_000123634.1 | hypothetical protein | - |
| L1A18_RS04955 (L1A18_04955) | 983969..984886 | + | 918 | WP_000587444.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| L1A18_RS04960 (L1A18_04960) | 984979..985827 | - | 849 | WP_000592062.1 | YitT family protein | - |
| L1A18_RS04965 (L1A18_04965) | 985969..986808 | + | 840 | WP_000161395.1 | DegV family protein | - |
| L1A18_RS04970 (L1A18_04970) | 986915..987190 | + | 276 | WP_001284639.1 | HU family DNA-binding protein | - |
| L1A18_RS04975 (L1A18_04975) | 987616..989517 | + | 1902 | WP_000584876.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| L1A18_RS04980 (L1A18_04980) | 989520..990383 | + | 864 | WP_000400552.1 | XRE/MutR family transcriptional regulator | - |
| L1A18_RS04985 (L1A18_04985) | 990463..991641 | + | 1179 | WP_001083012.1 | MFS transporter | - |
| L1A18_RS04990 (L1A18_04990) | 991734..993692 | + | 1959 | WP_001042603.1 | NAD-dependent DNA ligase LigA | - |
| L1A18_RS04995 (L1A18_04995) | 993804..996083 | + | 2280 | WP_000283076.1 | type I pullulanase | - |
| L1A18_RS05000 (L1A18_05000) | 996628..998052 | + | 1425 | WP_000199380.1 | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | - |
| L1A18_RS05005 (L1A18_05005) | 998532..1000430 | + | 1899 | WP_000370238.1 | 1,4-alpha-glucan branching protein GlgB | - |
| L1A18_RS05010 (L1A18_05010) | 1000450..1001592 | + | 1143 | WP_000787276.1 | glucose-1-phosphate adenylyltransferase | - |
| L1A18_RS05015 (L1A18_05015) | 1001582..1002721 | + | 1140 | WP_000687072.1 | glucose-1-phosphate adenylyltransferase subunit GlgD | - |
| L1A18_RS05020 (L1A18_05020) | 1002718..1004151 | + | 1434 | WP_000697294.1 | glycogen synthase GlgA | - |
| L1A18_RS05025 (L1A18_05025) | 1004210..1004581 | + | 372 | WP_001809343.1 | HAD-IB family phosphatase | - |
| L1A18_RS05030 (L1A18_05030) | 1004526..1004855 | + | 330 | WP_001809344.1 | HAD hydrolase family protein | - |
| L1A18_RS05035 (L1A18_05035) | 1004864..1005979 | + | 1116 | WP_000706418.1 | glycerate kinase | - |
| L1A18_RS05040 (L1A18_05040) | 1005976..1006422 | - | 447 | WP_000131076.1 | YueI family protein | - |
| L1A18_RS05045 (L1A18_05045) | 1006586..1007890 | + | 1305 | WP_000022813.1 | phosphopyruvate hydratase | - |
| L1A18_RS05050 (L1A18_05050) | 1008028..1008474 | - | 447 | WP_044811956.1 | tyrosine-type recombinase/integrase | - |
| L1A18_RS10645 | 1008374..1009202 | - | 829 | Protein_1005 | IS630 transposase-related protein | - |
| L1A18_RS05065 (L1A18_05065) | 1009256..1009431 | + | 176 | Protein_1006 | diacylglycerol kinase family lipid kinase | - |
| L1A18_RS05070 (L1A18_05070) | 1009631..1012906 | + | 3276 | WP_000772360.1 | ATP-dependent nuclease subunit B | - |
| L1A18_RS05075 (L1A18_05075) | 1012903..1016553 | + | 3651 | WP_000767247.1 | helicase-exonuclease AddAB subunit AddA | - |
| L1A18_RS05080 (L1A18_05080) | 1016515..1016682 | - | 168 | WP_001809348.1 | hypothetical protein | - |
| L1A18_RS05085 (L1A18_05085) | 1016768..1017946 | + | 1179 | WP_000174775.1 | hypothetical protein | - |
| L1A18_RS05090 (L1A18_05090) | 1018155..1024016 | + | 5862 | WP_000417147.1 | ZmpA/ZmpB/ZmpC family metallo-endopeptidase | - |
| L1A18_RS05095 (L1A18_05095) | 1024720..1024893 | + | 174 | WP_000159603.1 | hypothetical protein | - |
| L1A18_RS05100 (L1A18_05100) | 1024890..1025669 | + | 780 | WP_000822769.1 | replication initiator protein A | - |
| L1A18_RS05105 (L1A18_05105) | 1025768..1027126 | + | 1359 | WP_001210972.1 | DNA (cytosine-5-)-methyltransferase | - |
| L1A18_RS05110 (L1A18_05110) | 1027110..1027559 | + | 450 | WP_000645881.1 | hypothetical protein | - |
| L1A18_RS05115 (L1A18_05115) | 1027552..1027932 | + | 381 | WP_000566541.1 | hypothetical protein | - |
| L1A18_RS05120 (L1A18_05120) | 1027945..1028178 | + | 234 | WP_000840776.1 | hypothetical protein | - |
| L1A18_RS05125 (L1A18_05125) | 1028181..1028768 | + | 588 | WP_000821269.1 | type II CAAX endopeptidase family protein | - |
| L1A18_RS05130 (L1A18_05130) | 1028842..1029486 | + | 645 | WP_041974923.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| L1A18_RS05135 (L1A18_05135) | 1029486..1030322 | + | 837 | WP_000492401.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| L1A18_RS05140 (L1A18_05140) | 1030605..1030904 | + | 300 | WP_000869753.1 | hypothetical protein | - |
| L1A18_RS05145 (L1A18_05145) | 1030894..1031382 | + | 489 | WP_000093675.1 | hypothetical protein | - |
| L1A18_RS05150 (L1A18_05150) | 1031382..1033259 | + | 1878 | WP_001841466.1 | type IV secretory system conjugative DNA transfer family protein | - |
| L1A18_RS05155 (L1A18_05155) | 1033280..1033522 | + | 243 | WP_000627865.1 | hypothetical protein | - |
| L1A18_RS05160 (L1A18_05160) | 1033539..1034393 | + | 855 | WP_001054263.1 | conjugal transfer protein TrbL | - |
| L1A18_RS05165 (L1A18_05165) | 1034447..1034806 | + | 360 | WP_001097591.1 | PrgI family protein | - |
| L1A18_RS05170 (L1A18_05170) | 1034757..1037114 | + | 2358 | WP_000824170.1 | hypothetical protein | - |
| L1A18_RS05175 (L1A18_05175) | 1037126..1039939 | + | 2814 | WP_000653460.1 | phage tail tip lysozyme | - |
| L1A18_RS05180 (L1A18_05180) | 1040510..1040824 | + | 315 | WP_000420680.1 | YdcP family protein | - |
| L1A18_RS05185 (L1A18_05185) | 1040840..1041226 | + | 387 | WP_000985016.1 | DUF961 family protein | - |
| L1A18_RS05190 (L1A18_05190) | 1041266..1042660 | + | 1395 | WP_000813769.1 | FtsK/SpoIIIE domain-containing protein | - |
| L1A18_RS05195 (L1A18_05195) | 1042663..1042803 | + | 141 | WP_074186995.1 | conjugal transfer protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|