MGE detailed information
MGE type: Conjugative plasmid MGE length: 99606 bp
Accession: NZ_CP087566 Location: 1..99606 Organism: Escherichia coli strain CM2010-0578/1 Replicon: plasmid p10_578_2
Accession: NZ_CP087566 Location: 1..99606 Organism: Escherichia coli strain CM2010-0578/1 Replicon: plasmid p10_578_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LOF66_RS25615 (1) | 1..1032 | + | 1032 | WP_000907863.1 | plasmid replication initiator RepA | - |
| LOF66_RS25620 (1963) | 1963..2292 | + | 330 | WP_058649688.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LOF66_RS25625 (2273) | 2273..2554 | + | 282 | WP_058649687.1 | helix-turn-helix transcriptional regulator | - |
| LOF66_RS25630 (2574) | 2574..2837 | + | 264 | WP_058649686.1 | hypothetical protein | - |
| LOF66_RS25635 (3014) | 3014..3202 | + | 189 | WP_000957857.1 | hypothetical protein | - |
| LOF66_RS25640 (3425) | 3425..4624 | - | 1200 | WP_274480483.1 | IS91 family transposase ISSbo1 | Transposase |
| LOF66_RS25645 (4634) | 4634..4822 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| LOF66_RS25650 (4930) | 4930..6099 | + | 1170 | WP_274480489.1 | IS91 family transposase IS1294 | Transposase |
| LOF66_RS25655 (6230) | 6230..6502 | + | 273 | WP_265751832.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LOF66_RS25660 (7368) | 7368..8597 | + | 1230 | WP_274480488.1 | autotransporter strand-loop-strand O-heptosyltransferase | - |
| LOF66_RS25665 (8581) | 8581..12450 | + | 3870 | WP_274480487.1 | putative autotransporter | VF |
| LOF66_RS25670 (12739) | 12739..12858 | - | 120 | Protein_11 | IS91 family transposase | - |
| LOF66_RS25675 (13135) | 13135..14343 | - | 1209 | WP_274480490.1 | IS91 family transposase ISSbo1 | Transposase |
| LOF66_RS25680 (14324) | 14324..14596 | - | 273 | WP_113383268.1 | hypothetical protein | - |
| LOF66_RS25685 (14682) | 14682..14873 | + | 192 | Protein_14 | IS3 family transposase | - |
| LOF66_RS25690 (14943) | 14943..15122 | - | 180 | Protein_15 | ATP-binding protein | - |
| LOF66_RS25695 (15313) | 15313..15525 | + | 213 | WP_097330523.1 | hypothetical protein | - |
| LOF66_RS25700 (15648) | 15648..17186 | - | 1539 | WP_264831155.1 | IS66 family transposase ISEc8 | Transposase |
| LOF66_RS25705 (17236) | 17236..17583 | - | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| LOF66_RS25710 (17580) | 17580..17960 | - | 381 | WP_001171554.1 | IS66 family transposase ISEc8 | Transposase |
| LOF66_RS25715 (18049) | 18049..18660 | - | 612 | WP_171929858.1 | hypothetical protein | - |
| LOF66_RS25720 (18660) | 18660..18917 | - | 258 | WP_171929857.1 | hypothetical protein | - |
| LOF66_RS25725 (19230) | 19230..23024 | + | 3795 | WP_001144732.1 | hypothetical protein | - |
| LOF66_RS25730 (23069) | 23069..23485 | - | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| LOF66_RS25735 (23482) | 23482..23712 | - | 231 | WP_001261278.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| LOF66_RS25740 (24272) | 24272..24685 | + | 414 | WP_000465036.1 | hypothetical protein | - |
| LOF66_RS25745 (24687) | 24687..25466 | + | 780 | WP_001164201.1 | site-specific integrase | - |
| LOF66_RS25750 (25645) | 25645..26289 | + | 645 | WP_001144036.1 | ParA family protein | - |
| LOF66_RS25755 (26376) | 26376..26684 | + | 309 | WP_000030199.1 | hypothetical protein | - |
| LOF66_RS25760 (27098) | 27098..28078 | + | 981 | WP_000688514.1 | plasmid segregation protein ParM | - |
| LOF66_RS25765 (28071) | 28071..28487 | + | 417 | WP_001278818.1 | plasmid partitioning/stability family protein | - |
| LOF66_RS25770 (28489) | 28489..29763 | - | 1275 | WP_000457492.1 | Y-family DNA polymerase | - |
| LOF66_RS25775 (29763) | 29763..30200 | - | 438 | WP_000109071.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| LOF66_RS25780 (30197) | 30197..30445 | - | 249 | WP_000618110.1 | DinI-like family protein | - |
| LOF66_RS25785 (30863) | 30863..31348 | + | 486 | Protein_34 | DUF1281 domain-containing protein | - |
| LOF66_RS25790 (31342) | 31342..31671 | + | 330 | Protein_35 | DUF1380 family protein | - |
| LOF66_RS25795 (31717) | 31717..32493 | + | 777 | WP_015058197.1 | hypothetical protein | - |
| LOF66_RS25800 (32911) | 32911..33336 | + | 426 | WP_032072584.1 | antirestriction protein | - |
| LOF66_RS25805 (33383) | 33383..33805 | + | 423 | WP_015058200.1 | DUF1380 family protein | - |
| LOF66_RS25810 (33802) | 33802..33993 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| LOF66_RS25815 (34326) | 34326..34394 | - | 69 | Protein_40 | pilus protein | - |
| LOF66_RS25820 (34763) | 34763..35290 | + | 528 | WP_274480491.1 | single-stranded DNA-binding protein | - |
| LOF66_RS25825 (35348) | 35348..35581 | + | 234 | WP_000006012.1 | DUF905 family protein | - |
| LOF66_RS25830 (35640) | 35640..37598 | + | 1959 | WP_001145458.1 | ParB/RepB/Spo0J family partition protein | - |
| LOF66_RS25835 (37653) | 37653..38087 | + | 435 | WP_000845897.1 | conjugation system SOS inhibitor PsiB | - |
| LOF66_RS25840 (38084) | 38084..38803 | + | 720 | WP_001276260.1 | plasmid SOS inhibition protein A | - |
| LOF66_RS25845 (38933) | 38933..40108 | + | 1176 | WP_000942657.1 | IS200-IS605 family transposase ISEc46 | Transposase |
| LOF66_RS25850 (40556) | 40556..41056 | + | 501 | WP_000117626.1 | antirestriction protein ArdA | - |
| LOF66_RS25855 (41785) | 41785..42219 | + | 435 | WP_000218863.1 | hypothetical protein | - |
| LOF66_RS25860 (42313) | 42313..42579 | + | 267 | WP_001247862.1 | hypothetical protein | - |
| LOF66_RS25865 (42644) | 42644..43585 | + | 942 | WP_000038340.1 | Recombination-promoting nuclease RpnA | VF |
| LOF66_RS25870 (43647) | 43647..43853 | + | 207 | WP_021545175.1 | hypothetical protein | VF |
| LOF66_RS25875 (43884) | 43884..44135 | - | 252 | WP_000148285.1 | helix-turn-helix transcriptional regulator | - |
| LOF66_RS25880 (44715) | 44715..45563 | + | 849 | WP_001599394.1 | DUF4942 domain-containing protein | - |
| LOF66_RS25885 (45649) | 45649..45984 | - | 336 | WP_001599393.1 | hypothetical protein | - |
| LOF66_RS25890 (46218) | 46218..46550 | + | 333 | WP_001283947.1 | IncI1-type relaxosome accessory protein NikA | - |
| LOF66_RS25895 (46561) | 46561..49260 | + | 2700 | WP_001474686.1 | Protein TraI | Relaxase |
| LOF66_RS25900 (49297) | 49297..51588 | - | 2292 | WP_001289269.1 | F-type conjugative transfer protein TrbC | - |
| LOF66_RS25905 (51581) | 51581..52651 | - | 1071 | WP_000151576.1 | IncI1-type conjugal transfer protein TrbB | - |
| LOF66_RS25910 (52670) | 52670..53878 | - | 1209 | WP_000121273.1 | IncI1-type conjugal transfer protein TrbA | - |
| - (54058) | 54058..54120 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (54058) | 54058..54120 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (54058) | 54058..54120 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| - (54058) | 54058..54120 | - | 63 | NuclAT_0 | - | Antitoxin Detail |
| LOF66_RS25915 (54170) | 54170..54322 | + | 153 | WP_001303307.1 | Hok/Gef family protein | Toxin Detail |
| LOF66_RS25920 (54394) | 54394..54645 | - | 252 | WP_001291965.1 | hypothetical protein | - |
| - (55032) | 55032..55083 | - | 52 | NuclAT_1 | - | - |
| - (55032) | 55032..55083 | - | 52 | NuclAT_1 | - | - |
| - (55032) | 55032..55083 | - | 52 | NuclAT_1 | - | - |
| - (55032) | 55032..55083 | - | 52 | NuclAT_1 | - | - |
| LOF66_RS25925 (55569) | 55569..55745 | - | 177 | WP_001054900.1 | hypothetical protein | - |
| LOF66_RS25930 (56137) | 56137..56346 | + | 210 | WP_000062603.1 | HEAT repeat domain-containing protein | - |
| LOF66_RS25935 (56418) | 56418..57080 | - | 663 | WP_000644794.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| LOF66_RS25940 (57151) | 57151..59319 | - | 2169 | WP_000698368.1 | DotA/TraY family protein | - |
| LOF66_RS25945 (59416) | 59416..60000 | - | 585 | WP_001037985.1 | IncI1-type conjugal transfer protein TraX | - |
| LOF66_RS25950 (60029) | 60029..61231 | - | 1203 | WP_001189156.1 | IncI1-type conjugal transfer protein TraW | - |
| LOF66_RS25955 (61198) | 61198..61812 | - | 615 | WP_000337400.1 | IncI1-type conjugal transfer protein TraV | - |
| LOF66_RS25960 (61812) | 61812..64856 | - | 3045 | WP_044502553.1 | IncI1-type conjugal transfer protein TraU | - |
| LOF66_RS25965 (64946) | 64946..65746 | - | 801 | WP_001164788.1 | IncI1-type conjugal transfer protein TraT | - |
| LOF66_RS25970 (65730) | 65730..65918 | - | 189 | WP_001277255.1 | putative conjugal transfer protein TraS | - |
| LOF66_RS25975 (65982) | 65982..66386 | - | 405 | WP_000086960.1 | IncI1-type conjugal transfer protein TraR | - |
| LOF66_RS25980 (66437) | 66437..66964 | - | 528 | WP_001055569.1 | conjugal transfer protein TraQ | - |
| LOF66_RS25985 (66964) | 66964..67668 | - | 705 | WP_000801920.1 | IncI1-type conjugal transfer protein TraP | - |
| LOF66_RS25990 (67668) | 67668..68957 | - | 1290 | WP_001271997.1 | conjugal transfer protein TraO | - |
| LOF66_RS25995 (68960) | 68960..69943 | - | 984 | WP_001191878.1 | hypothetical protein | VF |
| LOF66_RS26000 (69954) | 69954..70646 | - | 693 | WP_000138552.1 | DotI/IcmL family type IV secretion protein | - |
| LOF66_RS26005 (70643) | 70643..70990 | - | 348 | WP_001055900.1 | conjugal transfer protein | - |
| LOF66_RS26010 (71008) | 71008..74775 | - | 3768 | WP_001141534.1 | DUF5710 domain-containing protein | - |
| LOF66_RS26015 (74865) | 74865..75416 | - | 552 | WP_000014584.1 | Phospholipase D | VF |
| LOF66_RS26020 (75431) | 75431..75721 | - | 291 | WP_114443197.1 | conjugal transfer protein | - |
| LOF66_RS26025 (75718) | 75718..76866 | - | 1149 | WP_001024972.1 | putative protein YggR | VF |
| LOF66_RS26030 (76863) | 76863..77681 | - | 819 | WP_000646097.1 | hypothetical protein | VF |
| LOF66_RS26035 (77678) | 77678..78136 | - | 459 | WP_001079808.1 | hypothetical protein | VF |
| LOF66_RS26040 (78531) | 78531..79115 | - | 585 | WP_000977522.1 | histidine phosphatase family protein | - |
| LOF66_RS26045 (79175) | 79175..80377 | - | 1203 | WP_000976353.1 | conjugal transfer protein TraF | - |
| LOF66_RS26050 (80463) | 80463..81287 | - | 825 | WP_001238927.1 | conjugal transfer protein TraE | - |
| LOF66_RS26055 (81438) | 81438..82592 | - | 1155 | WP_001139958.1 | site-specific integrase | - |
| LOF66_RS26060 (82591) | 82591..82998 | + | 408 | WP_003552681.1 | hypothetical protein | - |
| LOF66_RS26065 (82995) | 82995..84287 | - | 1293 | WP_001417545.1 | hypothetical protein | VF |
| LOF66_RS26070 (84287) | 84287..84943 | - | 657 | WP_001193554.1 | hypothetical protein | VF |
| LOF66_RS26075 (84928) | 84928..85488 | - | 561 | WP_000014116.1 | hypothetical protein | VF |
| LOF66_RS26080 (85498) | 85498..86112 | - | 615 | WP_000959785.1 | hypothetical protein | VF |
| LOF66_RS26085 (86130) | 86130..87227 | - | 1098 | WP_044502562.1 | Toxin coregulated pilus biosynthesis protein E | VF |
| LOF66_RS26090 (87240) | 87240..88793 | - | 1554 | WP_044502561.1 | Toxin coregulated pilus biosynthesis protein T | VF |
| LOF66_RS26095 (88804) | 88804..89256 | - | 453 | WP_044502560.1 | hypothetical protein | VF |
| LOF66_RS26100 (89243) | 89243..90538 | - | 1296 | WP_044502559.1 | type 4b pilus protein PilO2 | - |
| LOF66_RS26105 (90531) | 90531..92213 | - | 1683 | WP_000748143.1 | Outer membrane lipoprotein BfpB | VF |
| LOF66_RS26110 (92227) | 92227..92664 | - | 438 | WP_000539806.1 | hypothetical protein | VF |
| LOF66_RS26115 (92664) | 92664..93731 | - | 1068 | WP_001360287.1 | hypothetical protein | VF |
| LOF66_RS26120 (94652) | 94652..94948 | - | 297 | WP_000494780.1 | hypothetical protein | - |
| LOF66_RS26125 (95115) | 95115..95369 | - | 255 | WP_001136187.1 | PilI type IV pilus biogenesis protein | - |
| LOF66_RS26130 (95531) | 95531..96082 | - | 552 | WP_000744644.1 | hypothetical protein | - |
| LOF66_RS26135 (96255) | 96255..96938 | - | 684 | WP_000213859.1 | conjugal transfer protein TraC | - |
| LOF66_RS26140 (97191) | 97191..97724 | - | 534 | WP_001306770.1 | transcription termination/antitermination NusG family protein | - |
| LOF66_RS26145 (98166) | 98166..98453 | - | 288 | WP_000074849.1 | conjugal transfer protein TraA | - |
| LOF66_RS26150 (98371) | 98371..98649 | - | 279 | WP_219065241.1 | ash family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|