MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 134168 bp
Accession: NZ_CP085896 Location: 1..134168 Organism: Enterococcus faecium strain SC1762 Replicon: plasmid pSC1762-vanA
Accession: NZ_CP085896 Location: 1..134168 Organism: Enterococcus faecium strain SC1762 Replicon: plasmid pSC1762-vanA
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LK894_RS14900 (LK894_14920) | 1..475 | - | 475 | WP_194240989.1 | hypothetical protein | - |
| LK894_RS14905 (LK894_14925) | 642..908 | - | 267 | WP_010729835.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LK894_RS14910 (LK894_14930) | 910..1131 | - | 222 | WP_010729836.1 | DUF6290 family protein | - |
| LK894_RS14915 (LK894_14935) | 1357..2175 | + | 819 | WP_002360989.1 | AAA family ATPase | - |
| LK894_RS14920 (LK894_14940) | 2188..2475 | + | 288 | WP_010729837.1 | hypothetical protein | - |
| LK894_RS14925 (LK894_14945) | 2657..3010 | - | 354 | WP_002320794.1 | hypothetical protein | - |
| LK894_RS14930 (LK894_14950) | 3030..4085 | - | 1056 | WP_010730992.1 | ParM/StbA family protein | - |
| LK894_RS14935 (LK894_14955) | 4287..4685 | + | 399 | WP_010730993.1 | hypothetical protein | - |
| LK894_RS14940 (LK894_14960) | 4688..4861 | + | 174 | WP_002320797.1 | hypothetical protein | - |
| LK894_RS14945 (LK894_14965) | 6836..7009 | - | 174 | WP_002320797.1 | hypothetical protein | - |
| LK894_RS14950 (LK894_14970) | 7012..7410 | - | 399 | WP_010730993.1 | hypothetical protein | - |
| LK894_RS14955 (LK894_14975) | 7612..8667 | + | 1056 | WP_010730992.1 | ParM/StbA family protein | - |
| LK894_RS14960 (LK894_14980) | 8687..9040 | + | 354 | WP_002320794.1 | hypothetical protein | - |
| LK894_RS14965 (LK894_14985) | 9222..9509 | - | 288 | WP_010729837.1 | hypothetical protein | - |
| LK894_RS14970 (LK894_14990) | 9522..10340 | - | 819 | WP_002360989.1 | AAA family ATPase | - |
| LK894_RS14975 (LK894_14995) | 10566..10787 | + | 222 | WP_010729836.1 | DUF6290 family protein | - |
| LK894_RS14980 (LK894_15000) | 10789..11055 | + | 267 | WP_010729835.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LK894_RS14985 (LK894_15005) | 11222..11743 | + | 522 | WP_216661574.1 | hypothetical protein | - |
| LK894_RS14990 (LK894_15010) | 11771..12451 | + | 681 | WP_001015311.1 | IS6-like element IS1216 family transposase | - |
| LK894_RS14995 (LK894_15015) | 12678..13253 | + | 576 | WP_001226076.1 | recombinase family protein | - |
| LK894_RS15000 (LK894_15020) | 13475..14647 | - | 1173 | WP_002323245.1 | IS256-like element IS1542 family transposase | - |
| LK894_RS15005 (LK894_15025) | 14799..15494 | + | 696 | WP_001280781.1 | vancomycin resistance response regulator transcription factor VanR-A | - |
| LK894_RS15010 (LK894_15030) | 15472..16626 | + | 1155 | WP_002305818.1 | VanA-type vancomycin resistance histidine kinase VanS | - |
| LK894_RS15015 (LK894_15035) | 16841..17809 | + | 969 | WP_001059542.1 | D-lactate dehydrogenase VanH-A | - |
| LK894_RS15020 (LK894_15040) | 17802..18833 | + | 1032 | WP_001079845.1 | D-alanine--(R)-lactate ligase VanA | - |
| LK894_RS15025 (LK894_15045) | 18839..19447 | + | 609 | WP_000402347.1 | D-Ala-D-Ala dipeptidase VanX-A | - |
| LK894_RS15030 (LK894_15050) | 19609..20289 | - | 681 | WP_001015311.1 | IS6-like element IS1216 family transposase | - |
| LK894_RS15035 (LK894_15055) | 20397..21308 | + | 912 | WP_001812592.1 | D-Ala-D-Ala carboxypeptidase VanY-A | - |
| LK894_RS15040 (LK894_15060) | 21461..21946 | + | 486 | WP_000516404.1 | glycopeptide resistance protein VanZ-A | - |
| LK894_RS15045 (LK894_15065) | 22233..22562 | - | 330 | WP_000754864.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| LK894_RS15050 (LK894_15070) | 22867..23196 | + | 330 | WP_000629052.1 | hypothetical protein | - |
| LK894_RS15055 (LK894_15075) | 23186..23473 | + | 288 | WP_000312841.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LK894_RS15060 (LK894_15080) | 23752..24315 | - | 564 | WP_000017403.1 | recombinase family protein | - |
| LK894_RS15065 (LK894_15085) | 24508..25080 | - | 573 | WP_002293724.1 | HAD-IIIA family hydrolase | - |
| LK894_RS15070 (LK894_15090) | 25868..26443 | + | 576 | WP_002293722.1 | hypothetical protein | - |
| LK894_RS15075 (LK894_15095) | 26626..27378 | - | 753 | WP_002325566.1 | IS21-like element helper ATPase IstB | - |
| LK894_RS15080 (LK894_15100) | 27378..28919 | - | 1542 | WP_010730990.1 | IS21 family transposase | - |
| LK894_RS15085 (LK894_15105) | 29833..30297 | + | 465 | WP_010730988.1 | DUF5626 family protein | - |
| LK894_RS15090 (LK894_15110) | 30294..30794 | - | 501 | WP_256880954.1 | helix-turn-helix transcriptional regulator | - |
| LK894_RS15095 (LK894_15115) | 30868..31503 | - | 636 | WP_010730987.1 | LCP family protein | - |
| LK894_RS15100 (LK894_15120) | 31565..32245 | + | 681 | WP_001015311.1 | IS6-like element IS1216 family transposase | - |
| LK894_RS15105 (LK894_15125) | 32329..32583 | + | 255 | WP_002347534.1 | hypothetical protein | - |
| LK894_RS15110 (LK894_15130) | 32665..32850 | + | 186 | WP_002320785.1 | type II toxin-antitoxin system HicA family toxin | - |
| LK894_RS15115 (LK894_15135) | 32917..33312 | + | 396 | WP_002320784.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| LK894_RS15120 (LK894_15140) | 33329..33679 | + | 351 | WP_002347533.1 | hypothetical protein | - |
| LK894_RS15125 (LK894_15145) | 33701..34075 | + | 375 | WP_002347532.1 | hypothetical protein | - |
| LK894_RS15130 (LK894_15150) | 34484..35632 | - | 1149 | WP_002287525.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| LK894_RS15135 (LK894_15155) | 35649..36053 | - | 405 | WP_079158048.1 | IS200/IS605-like element ISEfa4 family transposase | - |
| LK894_RS15140 (LK894_15160) | 36273..36671 | - | 399 | WP_002320781.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| LK894_RS15145 (LK894_15165) | 36863..37630 | - | 768 | WP_010729833.1 | replication initiation protein | - |
| LK894_RS15150 (LK894_15170) | 37665..38825 | - | 1161 | WP_010730986.1 | RepB family plasmid replication initiator protein | - |
| LK894_RS15155 (LK894_15175) | 39388..39987 | + | 600 | Protein_51 | IS1182-like element ISEfa7 family transposase | - |
| LK894_RS15160 (LK894_15180) | 40062..40742 | + | 681 | WP_001015311.1 | IS6-like element IS1216 family transposase | - |
| LK894_RS15165 (LK894_15185) | 40800..42383 | + | 1584 | WP_002347719.1 | hypothetical protein | - |
| LK894_RS15170 (LK894_15190) | 42640..42975 | - | 336 | WP_010729677.1 | hypothetical protein | - |
| LK894_RS15175 (LK894_15195) | 43182..44330 | - | 1149 | WP_002287525.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| LK894_RS15180 (LK894_15200) | 44347..44751 | - | 405 | WP_002287522.1 | IS200/IS605-like element ISEfa4 family transposase | - |
| LK894_RS15185 (LK894_15205) | 44837..45094 | - | 258 | WP_002347721.1 | hypothetical protein | - |
| LK894_RS15190 (LK894_15210) | 45261..47231 | - | 1971 | WP_002320766.1 | hypothetical protein | - |
| LK894_RS15195 (LK894_15215) | 47246..48112 | - | 867 | WP_002320767.1 | hypothetical protein | - |
| LK894_RS15200 (LK894_15220) | 48102..48335 | - | 234 | WP_002320768.1 | LPXTG cell wall anchor domain-containing protein | - |
| LK894_RS15205 (LK894_15225) | 48347..50503 | - | 2157 | WP_002347429.1 | hypothetical protein | - |
| LK894_RS15210 | 50523..50768 | - | 246 | WP_224211763.1 | hypothetical protein | - |
| LK894_RS15215 (LK894_15230) | 50854..51192 | - | 339 | WP_002347431.1 | hypothetical protein | - |
| LK894_RS15220 (LK894_15235) | 51592..55233 | - | 3642 | WP_222036318.1 | DUF3659 domain-containing protein | - |
| LK894_RS15225 (LK894_15240) | 55236..57185 | - | 1950 | WP_010729681.1 | AAA family ATPase | - |
| LK894_RS15230 (LK894_15245) | 57227..58285 | - | 1059 | WP_010729682.1 | hypothetical protein | - |
| LK894_RS15235 (LK894_15250) | 58404..58859 | - | 456 | WP_002320776.1 | hypothetical protein | - |
| LK894_RS15240 (LK894_15255) | 59443..60246 | - | 804 | WP_002320777.1 | replication initiation protein | - |
| LK894_RS15245 (LK894_15260) | 60778..61647 | - | 870 | Protein_69 | IS1182-like element ISEfa7 family transposase | - |
| LK894_RS15250 (LK894_15265) | 61704..62384 | - | 681 | WP_001015311.1 | IS6-like element IS1216 family transposase | - |
| LK894_RS15255 (LK894_15270) | 62455..63057 | + | 603 | Protein_71 | ParA family protein | - |
| LK894_RS15260 (LK894_15275) | 63029..63304 | + | 276 | WP_001196543.1 | DNA segregation protein PrgO | - |
| LK894_RS15265 (LK894_15280) | 63497..63751 | + | 255 | WP_000199136.1 | transposase | - |
| LK894_RS15275 (LK894_15290) | 64157..65319 | + | 1163 | WP_086956687.1 | IS3 family transposase | - |
| LK894_RS15280 (LK894_15295) | 65495..65992 | + | 498 | WP_228780308.1 | IS3 family transposase | - |
| LK894_RS15285 (LK894_15300) | 66465..67037 | - | 573 | WP_002303206.1 | recombinase family protein | - |
| LK894_RS15290 (LK894_15305) | 67053..67658 | - | 606 | WP_000599739.1 | Fic family protein | - |
| LK894_RS15295 (LK894_15310) | 67856..68536 | - | 681 | WP_001015311.1 | IS6-like element IS1216 family transposase | - |
| LK894_RS15300 (LK894_15315) | 68612..69106 | - | 495 | Protein_79 | transposase family protein | - |
| LK894_RS15305 (LK894_15320) | 69351..69602 | + | 252 | Protein_80 | GNAT family N-acetyltransferase | - |
| LK894_RS15310 (LK894_15325) | 69695..70489 | + | 795 | WP_001096887.1 | aminoglycoside O-phosphotransferase APH(3')-IIIa | - |
| LK894_RS15315 (LK894_15330) | 71152..72471 | - | 1320 | WP_000202380.1 | IS1380-like element IS1678 family transposase | - |
| LK894_RS15320 (LK894_15335) | 72715..72798 | + | 84 | WP_031929417.1 | 23S rRNA methyltransferase attenuator leader peptide ErmL | - |
| LK894_RS15325 (LK894_15340) | 72923..73660 | + | 738 | WP_001038796.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | - |
| LK894_RS15330 (LK894_15345) | 73923..74786 | - | 864 | WP_001284311.1 | zeta toxin family protein | Toxin Detail |
| LK894_RS15335 (LK894_15350) | 74788..75060 | - | 273 | WP_000301765.1 | antitoxin | Antitoxin Detail |
| LK894_RS15340 (LK894_15355) | 75077..75292 | - | 216 | WP_001835296.1 | peptide-binding protein | - |
| LK894_RS15345 (LK894_15360) | 75384..75488 | - | 105 | Protein_88 | chromosome partitioning protein ParA | - |
| LK894_RS15350 (LK894_15365) | 75542..76222 | - | 681 | WP_001015311.1 | IS6-like element IS1216 family transposase | - |
| LK894_RS15355 (LK894_15370) | 76423..77007 | + | 585 | WP_002347505.1 | hypothetical protein | - |
| LK894_RS15360 (LK894_15375) | 77018..77263 | + | 246 | WP_002347506.1 | hypothetical protein | - |
| LK894_RS15365 (LK894_15380) | 77269..77991 | + | 723 | WP_222036300.1 | hypothetical protein | - |
| LK894_RS15370 (LK894_15385) | 78121..78864 | + | 744 | WP_016922485.1 | hypothetical protein | - |
| LK894_RS15375 (LK894_15390) | 78870..79235 | + | 366 | WP_002347509.1 | hypothetical protein | - |
| LK894_RS15380 (LK894_15395) | 79251..79781 | + | 531 | WP_002347720.1 | hypothetical protein | - |
| LK894_RS15385 (LK894_15400) | 79943..80308 | + | 366 | WP_016922483.1 | hypothetical protein | - |
| LK894_RS15390 (LK894_15405) | 80325..80714 | + | 390 | WP_002350513.1 | hypothetical protein | - |
| LK894_RS15395 (LK894_15410) | 80744..80968 | + | 225 | WP_002350512.1 | hypothetical protein | - |
| LK894_RS15400 (LK894_15415) | 81021..81302 | + | 282 | WP_002350511.1 | hypothetical protein | - |
| LK894_RS15405 (LK894_15420) | 81283..81525 | + | 243 | WP_002350510.1 | hypothetical protein | - |
| LK894_RS15410 (LK894_15425) | 81647..81895 | + | 249 | WP_002350509.1 | hypothetical protein | - |
| LK894_RS15415 (LK894_15430) | 81922..82086 | + | 165 | WP_002350508.1 | hypothetical protein | - |
| LK894_RS15420 (LK894_15435) | 82170..82382 | + | 213 | WP_002350507.1 | hypothetical protein | - |
| LK894_RS15425 (LK894_15440) | 82491..82667 | + | 177 | WP_002350506.1 | hypothetical protein | - |
| LK894_RS15430 (LK894_15445) | 82712..82999 | + | 288 | WP_002350505.1 | hypothetical protein | - |
| LK894_RS15435 (LK894_15450) | 83416..85611 | + | 2196 | WP_227889214.1 | hypothetical protein | - |
| LK894_RS15440 (LK894_15455) | 85749..86546 | + | 798 | WP_002350503.1 | hypothetical protein | - |
| LK894_RS15445 (LK894_15460) | 86586..86768 | + | 183 | WP_002350502.1 | hypothetical protein | - |
| LK894_RS15450 (LK894_15465) | 86812..87099 | + | 288 | WP_002321018.1 | hypothetical protein | - |
| LK894_RS15455 (LK894_15470) | 87136..87423 | + | 288 | WP_002321017.1 | hypothetical protein | - |
| LK894_RS15460 (LK894_15475) | 87514..87753 | + | 240 | WP_002350501.1 | hypothetical protein | - |
| LK894_RS15465 (LK894_15480) | 87881..88210 | + | 330 | WP_002350500.1 | hypothetical protein | - |
| LK894_RS15470 (LK894_15485) | 88263..89093 | + | 831 | WP_044382020.1 | hypothetical protein | - |
| LK894_RS15475 (LK894_15490) | 89108..89425 | + | 318 | WP_002347440.1 | hypothetical protein | - |
| LK894_RS15480 (LK894_15495) | 89428..89661 | + | 234 | WP_044382017.1 | hypothetical protein | - |
| LK894_RS15485 (LK894_15500) | 89777..90256 | - | 480 | WP_002350498.1 | hypothetical protein | - |
| LK894_RS15490 (LK894_15505) | 90406..91713 | + | 1308 | WP_227889215.1 | phage tail tip lysozyme | - |
| LK894_RS15495 (LK894_15510) | 91736..92263 | + | 528 | WP_002350496.1 | hypothetical protein | - |
| LK894_RS15500 (LK894_15515) | 92250..92813 | + | 564 | WP_016922277.1 | hypothetical protein | - |
| LK894_RS15505 (LK894_15520) | 93236..93973 | + | 738 | WP_010782614.1 | hypothetical protein | - |
| LK894_RS15510 (LK894_15525) | 93990..94406 | - | 417 | WP_002350493.1 | hypothetical protein | - |
| LK894_RS15515 (LK894_15530) | 94804..96045 | + | 1242 | WP_010782613.1 | C39 family peptidase | - |
| LK894_RS15520 (LK894_15535) | 96315..98705 | + | 2391 | WP_016922338.1 | SpaA isopeptide-forming pilin-related protein | - |
| LK894_RS15525 (LK894_15540) | 98754..100589 | + | 1836 | WP_002350584.1 | SpaA isopeptide-forming pilin-related protein | - |
| LK894_RS15530 (LK894_15545) | 100664..101521 | + | 858 | WP_010730978.1 | class C sortase | - |
| LK894_RS15535 (LK894_15550) | 101511..102620 | + | 1110 | WP_002350582.1 | class C sortase | - |
| LK894_RS15540 (LK894_15555) | 102959..103759 | + | 801 | WP_010730977.1 | hypothetical protein | - |
| LK894_RS15545 (LK894_15560) | 103865..104653 | + | 789 | WP_010730976.1 | hypothetical protein | - |
| LK894_RS15550 (LK894_15565) | 104885..105754 | + | 870 | WP_010729859.1 | DNA/RNA non-specific endonuclease | - |
| LK894_RS15555 (LK894_15570) | 105774..106121 | + | 348 | WP_002320856.1 | hypothetical protein | - |
| LK894_RS15560 (LK894_15575) | 106134..107396 | + | 1263 | WP_002320855.1 | hypothetical protein | - |
| LK894_RS15565 (LK894_15580) | 107476..108852 | + | 1377 | WP_002320854.1 | FtsK/SpoIIIE domain-containing protein | - |
| LK894_RS15570 (LK894_15585) | 108849..109478 | + | 630 | WP_002320853.1 | hypothetical protein | - |
| LK894_RS15575 (LK894_15590) | 109696..110100 | + | 405 | WP_002287522.1 | IS200/IS605-like element ISEfa4 family transposase | - |
| LK894_RS15580 (LK894_15595) | 110117..111265 | + | 1149 | WP_002287525.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| LK894_RS15585 (LK894_15600) | 111439..111867 | + | 429 | WP_152630967.1 | hypothetical protein | - |
| LK894_RS16520 | 111927..112448 | + | 522 | WP_002347459.1 | hypothetical protein | - |
| LK894_RS15595 (LK894_15610) | 112426..113025 | + | 600 | WP_016922336.1 | rhomboid family intramembrane serine protease | - |
| LK894_RS15600 (LK894_15615) | 113041..113517 | + | 477 | WP_002350576.1 | hypothetical protein | - |
| LK894_RS15605 (LK894_15620) | 113534..114436 | + | 903 | WP_016922335.1 | hypothetical protein | - |
| LK894_RS15610 (LK894_15625) | 114509..114703 | + | 195 | WP_138821081.1 | hypothetical protein | - |
| LK894_RS15615 (LK894_15630) | 114808..115236 | + | 429 | WP_042957131.1 | hypothetical protein | - |
| LK894_RS15620 (LK894_15635) | 115471..116058 | + | 588 | WP_002350572.1 | hypothetical protein | - |
| LK894_RS15625 (LK894_15640) | 116058..116957 | + | 900 | WP_002350571.1 | RusA family crossover junction endodeoxyribonuclease | - |
| LK894_RS15630 (LK894_15645) | 116957..117871 | + | 915 | WP_016922248.1 | hypothetical protein | - |
| LK894_RS15635 (LK894_15650) | 117923..118138 | + | 216 | WP_016922247.1 | hypothetical protein | - |
| LK894_RS15640 (LK894_15655) | 118328..118582 | + | 255 | WP_002350568.1 | hypothetical protein | - |
| LK894_RS15645 (LK894_15660) | 118794..119810 | + | 1017 | WP_224797034.1 | C39 family peptidase | - |
| LK894_RS15650 (LK894_15665) | 119987..120217 | + | 231 | WP_002320840.1 | hypothetical protein | - |
| LK894_RS15655 (LK894_15670) | 120253..120477 | + | 225 | WP_010730974.1 | hypothetical protein | - |
| LK894_RS15660 (LK894_15675) | 120694..121569 | + | 876 | WP_010730973.1 | hypothetical protein | - |
| LK894_RS15665 (LK894_15680) | 121579..122373 | + | 795 | WP_010730972.1 | hypothetical protein | - |
| LK894_RS15670 (LK894_15685) | 122402..123520 | + | 1119 | WP_010730971.1 | hypothetical protein | - |
| LK894_RS15675 (LK894_15690) | 123553..123873 | + | 321 | WP_002321530.1 | hypothetical protein | - |
| LK894_RS15680 (LK894_15695) | 124128..124817 | + | 690 | WP_002347494.1 | hypothetical protein | - |
| LK894_RS15685 (LK894_15700) | 124854..125021 | + | 168 | WP_154080629.1 | hypothetical protein | - |
| LK894_RS15690 (LK894_15705) | 125041..126669 | + | 1629 | WP_227889216.1 | hypothetical protein | - |
| LK894_RS15695 (LK894_15710) | 126720..127091 | + | 372 | WP_002347492.1 | hypothetical protein | - |
| LK894_RS15700 (LK894_15715) | 127176..127376 | + | 201 | WP_002347491.1 | hypothetical protein | - |
| LK894_RS15705 (LK894_15720) | 127543..128736 | + | 1194 | WP_225309896.1 | hypothetical protein | - |
| LK894_RS15710 (LK894_15725) | 129586..130910 | + | 1325 | Protein_161 | Y-family DNA polymerase | - |
| LK894_RS15715 (LK894_15730) | 130903..131250 | + | 348 | WP_002347528.1 | hypothetical protein | - |
| LK894_RS15720 (LK894_15735) | 131247..131429 | + | 183 | WP_002320829.1 | hypothetical protein | - |
| LK894_RS15725 (LK894_15740) | 131565..132422 | + | 858 | WP_002320757.1 | nucleotidyltransferase domain-containing protein | - |
| LK894_RS15730 (LK894_15745) | 132442..133002 | + | 561 | WP_002320756.1 | SLATT domain-containing protein | - |
| LK894_RS15735 (LK894_15750) | 133891..134168 | + | 278 | Protein_166 | DNA repair protein RadC | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|