MGE detailed information
MGE type: Conjugative plasmid MGE length: 142244 bp
Accession: NZ_CP084988 Location: 1..142244 Organism: Klebsiella pneumoniae strain KP18-2110-2 Replicon: plasmid pKP18-2110-2-2
Accession: NZ_CP084988 Location: 1..142244 Organism: Klebsiella pneumoniae strain KP18-2110-2 Replicon: plasmid pKP18-2110-2-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LH404_RS28015 | 1..1020 | + | 1020 | WP_009652816.1 | plasmid replication initiator RepA | - |
| LH404_RS28020 | 2005..2184 | + | 180 | Protein_1 | SOS response-associated peptidase | - |
| LH404_RS28025 | 2514..5321 | - | 2808 | WP_040228250.1 | SNF2-related protein | - |
| LH404_RS28030 | 5331..5831 | - | 501 | WP_040228248.1 | hypothetical protein | - |
| LH404_RS28035 | 5831..9046 | - | 3216 | WP_040228246.1 | DUF1156 domain-containing protein | - |
| LH404_RS28040 | 9057..10850 | - | 1794 | WP_064176592.1 | ATP-binding protein | - |
| LH404_RS28045 | 10858..11934 | - | 1077 | WP_040228241.1 | SIR2 family protein | - |
| LH404_RS28050 | 11941..12960 | - | 1020 | WP_040227127.1 | hypothetical protein | - |
| LH404_RS28055 | 12960..15077 | - | 2118 | WP_088903447.1 | DUF499 domain-containing protein | - |
| LH404_RS28060 | 15456..16073 | + | 618 | Protein_9 | replication protein | - |
| LH404_RS28065 | 16607..16885 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| LH404_RS28070 | 16996..17421 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| LH404_RS28075 | 17549..17704 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| LH404_RS28080 | 17750..18046 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| LH404_RS28085 | 18150..19031 | + | 882 | Protein_14 | IS1182 family transposase ISKpn6 | Transposase |
| LH404_RS28090 | 19281..20162 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| LH404_RS28095 | 20438..21418 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| LH404_RS28100 | 21541..22098 | - | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| LH404_RS28105 | 22261..25266 | + | 3006 | WP_001143760.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| LH404_RS28110 | 25268..25654 | + | 387 | WP_223289724.1 | HNH endonuclease | - |
| LH404_RS28115 | 25692..25970 | + | 279 | WP_020314648.1 | hypothetical protein | - |
| LH404_RS28120 | 26288..26899 | + | 612 | WP_020804876.1 | DUF2913 family protein | - |
| LH404_RS28125 | 26896..27849 | - | 954 | WP_020314639.1 | Recombination-promoting nuclease RpnA | VF |
| LH404_RS28130 | 27974..28237 | - | 264 | WP_088903441.1 | hypothetical protein | - |
| LH404_RS28135 | 28257..28877 | - | 621 | WP_020314642.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| LH404_RS28140 | 29256..30689 | + | 1434 | WP_075606933.1 | DNA cytosine methyltransferase | - |
| LH404_RS28145 | 30724..31938 | - | 1215 | WP_148237948.1 | type II restriction endonuclease | - |
| LH404_RS28150 | 32246..34999 | + | 2754 | WP_075606932.1 | ABC transporter | - |
| LH404_RS28155 | 35105..35701 | - | 597 | WP_032635043.1 | Tn3 family transposase TnpR_ISYps3 | Transposase |
| LH404_RS28160 | 35954..36472 | - | 519 | WP_088903439.1 | hypothetical protein | - |
| LH404_RS28165 | 37377..38003 | + | 627 | WP_022644718.1 | ParA family protein | - |
| LH404_RS28170 | 38048..38275 | + | 228 | WP_020314634.1 | hypothetical protein | - |
| LH404_RS28175 | 38450..39724 | - | 1275 | WP_020314652.1 | Y-family DNA polymerase | - |
| LH404_RS28180 | 39736..40197 | - | 462 | WP_022644717.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| LH404_RS28185 | 40182..40427 | - | 246 | WP_020314635.1 | DinI-like family protein | - |
| LH404_RS28190 | 40631..40861 | + | 231 | WP_020314631.1 | hypothetical protein | - |
| LH404_RS28195 | 41031..41224 | + | 194 | Protein_36 | hypothetical protein | - |
| LH404_RS28200 | 41296..41886 | + | 591 | Protein_37 | DNA methyltransferase | - |
| LH404_RS28205 | 41916..44813 | - | 2898 | WP_023307208.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| LH404_RS28210 | 44908..45513 | + | 606 | Protein_39 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| LH404_RS28215 | 45546..45638 | - | 93 | Protein_40 | SMR family transporter | - |
| LH404_RS28220 | 46173..47354 | + | 1182 | WP_004194048.1 | Na+/H+ antiporter NhaA | - |
| LH404_RS28225 | 47781..48095 | - | 315 | WP_000091613.1 | hypothetical protein | - |
| LH404_RS28230 | 48350..48706 | - | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| LH404_RS28235 | 48696..49097 | - | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| LH404_RS28240 | 49094..49384 | - | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| LH404_RS28245 | 49459..52425 | + | 2967 | WP_003100881.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| LH404_RS28250 | 52504..53508 | + | 1005 | WP_000427623.1 | IS110 family transposase IS4321R | Transposase |
| LH404_RS28255 | 53690..53893 | - | 204 | WP_004197809.1 | hypothetical protein | - |
| LH404_RS28260 | 53907..54110 | - | 204 | WP_004197808.1 | HHA domain-containing protein | - |
| LH404_RS28265 | 54144..54512 | - | 369 | WP_004197807.1 | hypothetical protein | - |
| LH404_RS28270 | 54556..55050 | - | 495 | WP_020805591.1 | hypothetical protein | - |
| LH404_RS28275 | 55081..55653 | - | 573 | WP_020805590.1 | hypothetical protein | - |
| LH404_RS28280 | 55650..55898 | - | 249 | WP_000272716.1 | hypothetical protein | - |
| LH404_RS28285 | 56335..57024 | + | 690 | WP_020315560.1 | RES family NAD+ phosphorylase | - |
| LH404_RS28290 | 57056..57745 | - | 690 | WP_004193995.1 | hypothetical protein | - |
| LH404_RS28295 | 58012..58893 | + | 882 | WP_223289722.1 | hypothetical protein | - |
| LH404_RS28300 | 58995..59243 | + | 249 | WP_053389907.1 | hypothetical protein | - |
| LH404_RS28305 | 59297..60283 | - | 987 | WP_223289723.1 | hypothetical protein | - |
| LH404_RS28310 | 60421..60675 | + | 255 | Protein_59 | hypothetical protein | - |
| LH404_RS28315 | 60845..61063 | + | 219 | WP_001568025.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| LH404_RS28320 | 61065..61370 | + | 306 | WP_013023785.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| LH404_RS28325 | 61539..61934 | + | 396 | WP_162269742.1 | hypothetical protein | - |
| LH404_RS28330 | 61961..62275 | + | 315 | WP_053389906.1 | hypothetical protein | - |
| LH404_RS28335 | 62286..63302 | + | 1017 | WP_017899884.1 | hypothetical protein | - |
| LH404_RS28340 | 63500..64294 | + | 795 | WP_053389905.1 | site-specific integrase | - |
| LH404_RS28345 | 64726..65028 | - | 303 | WP_004197636.1 | hypothetical protein | - |
| LH404_RS28350 | 65025..65651 | - | 627 | WP_004197649.1 | Chromosome-partitioning ATPase Soj | VF |
| LH404_RS28355 | 66260..67135 | - | 876 | WP_004098982.1 | replication initiation protein | - |
| LH404_RS28360 | 67547..68818 | - | 1272 | WP_053390143.1 | Y-family DNA polymerase | - |
| LH404_RS28365 | 68818..69249 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| LH404_RS28370 | 69655..71142 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| LH404_RS28375 | 71391..72362 | + | 972 | WP_004152353.1 | plasmid segregation protein ParM | - |
| LH404_RS28380 | 72365..73036 | + | 672 | WP_053390142.1 | plasmid partitioning/stability family protein | - |
| LH404_RS28385 | 73100..73330 | + | 231 | WP_023329036.1 | hypothetical protein | - |
| LH404_RS28390 | 73526..73695 | + | 170 | Protein_75 | hypothetical protein | - |
| LH404_RS28395 | 73767..74468 | + | 702 | WP_004152355.1 | DNA methylase | - |
| LH404_RS28400 | 74468..74689 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| LH404_RS28405 | 74699..75118 | + | 420 | WP_053390283.1 | DUF1380 family protein | - |
| LH404_RS28410 | 75172..75939 | + | 768 | WP_110522032.1 | hypothetical protein | - |
| LH404_RS28415 | 76620..77048 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| LH404_RS28420 | 77091..77597 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| LH404_RS28425 | 77640..77831 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| LH404_RS28430 | 78019..78273 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| LH404_RS28435 | 78308..78628 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| LH404_RS28440 | 79308..79535 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| LH404_RS28445 | 79627..79857 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| LH404_RS28450 | 79909..81264 | + | 1356 | WP_053390261.1 | DUF3560 domain-containing protein | - |
| LH404_RS28455 | 81312..81875 | + | 564 | WP_004152756.1 | methyltransferase | - |
| LH404_RS28460 | 82706..83248 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| LH404_RS28465 | 83297..83545 | + | 249 | WP_009310026.1 | DUF905 domain-containing protein | - |
| LH404_RS28470 | 83615..85672 | + | 2058 | WP_009310025.1 | ParB/RepB/Spo0J family partition protein | - |
| LH404_RS28475 | 85717..86148 | + | 432 | WP_020804497.1 | conjugation system SOS inhibitor PsiB | - |
| LH404_RS28480 | 86145..86873 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| LH404_RS28485 | 86870..87196 | + | 327 | WP_001568059.1 | hypothetical protein | - |
| LH404_RS28490 | 87252..87626 | + | 375 | WP_023280872.1 | hypothetical protein | - |
| LH404_RS28495 | 87827..89202 | + | 1376 | WP_100250078.1 | IS3 family transposase | - |
| LH404_RS28500 | 89372..90412 | + | 1041 | WP_009310020.1 | ATP-binding protein | - |
| LH404_RS28505 | 90390..92900 | + | 2511 | WP_071826167.1 | S8 family peptidase | - |
| LH404_RS28510 | 93218..93367 | + | 150 | Protein_99 | DUF5431 family protein | - |
| LH404_RS28515 | 93318..93434 | + | 117 | WP_055313929.1 | type I toxin-antitoxin system Hok family toxin | - |
| LH404_RS28520 | 93800..94204 | + | 405 | WP_053390087.1 | IS66 family transposase ISKpn24 | Transposase |
| LH404_RS28525 | 94201..94548 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| LH404_RS28530 | 94597..96135 | + | 1539 | WP_048213845.1 | IS66 family transposase ISKpn24 | Transposase |
| LH404_RS28535 | 96594..96866 | + | 273 | WP_023287105.1 | hypothetical protein | - |
| LH404_RS28540 | 96863..97213 | + | 351 | WP_023287104.1 | hypothetical protein | - |
| LH404_RS28545 | 97845..98201 | + | 357 | WP_019706019.1 | hypothetical protein | - |
| LH404_RS28550 | 98262..98474 | + | 213 | WP_019706020.1 | hypothetical protein | - |
| LH404_RS28555 | 98485..98709 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| LH404_RS28560 | 98790..99110 | + | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LH404_RS28565 | 99100..99378 | + | 279 | WP_004152721.1 | helix-turn-helix transcriptional regulator | - |
| LH404_RS28570 | 99379..99792 | + | 414 | WP_023287139.1 | helix-turn-helix domain-containing protein | - |
| LH404_RS28575 | 100622..101443 | + | 822 | WP_004152492.1 | DUF932 domain-containing protein | - |
| LH404_RS28580 | 101476..101805 | + | 330 | WP_053390269.1 | DUF5983 family protein | - |
| LH404_RS28585 | 101838..102323 | - | 486 | WP_001568108.1 | hypothetical protein | VF |
| LH404_RS28590 | 102757..103149 | + | 393 | WP_053390193.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| LH404_RS28595 | 103387..104088 | + | 702 | WP_094898581.1 | hypothetical protein | - |
| LH404_RS28600 | 104249..104410 | + | 162 | WP_172686697.1 | TraY domain-containing protein | - |
| LH404_RS28605 | 104475..104843 | + | 369 | WP_064386081.1 | type IV conjugative transfer system pilin TraA | - |
| LH404_RS28610 | 104857..105162 | + | 306 | WP_064343526.1 | type IV conjugative transfer system protein TraL | - |
| LH404_RS28615 | 105178..105744 | + | 567 | WP_064359954.1 | type IV conjugative transfer system protein TraE | - |
| LH404_RS28620 | 105731..106465 | + | 735 | WP_064343528.1 | type-F conjugative transfer system secretin TraK | - |
| LH404_RS28625 | 106465..107886 | + | 1422 | WP_053390199.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| LH404_RS28630 | 107879..108313 | + | 435 | WP_020322358.1 | conjugal transfer protein TraP | - |
| LH404_RS28635 | 108347..108931 | + | 585 | WP_064343530.1 | type IV conjugative transfer system lipoprotein TraV | - |
| LH404_RS28640 | 109544..109732 | + | 189 | WP_053390286.1 | hypothetical protein | - |
| LH404_RS28645 | 109816..110217 | + | 402 | WP_064343532.1 | hypothetical protein | - |
| LH404_RS28650 | 110214..110513 | + | 300 | WP_181726264.1 | hypothetical protein | - |
| LH404_RS28655 | 110601..110984 | + | 384 | WP_042946290.1 | hypothetical protein | - |
| LH404_RS28660 | 111077..113716 | + | 2640 | WP_226742944.1 | type IV secretion system protein TraC | - |
| LH404_RS28665 | 113716..114108 | + | 393 | WP_064343534.1 | type-F conjugative transfer system protein TrbI | - |
| LH404_RS28670 | 114105..114731 | + | 627 | WP_064343535.1 | type-F conjugative transfer system protein TraW | - |
| LH404_RS28675 | 114775..115734 | + | 960 | WP_229295972.1 | conjugal transfer pilus assembly protein TraU | - |
| LH404_RS28680 | 115747..116394 | + | 648 | WP_064343536.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| LH404_RS28685 | 116391..116774 | + | 384 | WP_053390297.1 | hypothetical protein | - |
| LH404_RS28690 | 116771..118726 | + | 1956 | WP_064343537.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| LH404_RS28695 | 118758..119018 | + | 261 | WP_053390216.1 | hypothetical protein | - |
| LH404_RS28700 | 119011..119622 | + | 612 | WP_053390217.1 | hypothetical protein | - |
| LH404_RS28705 | 119612..119854 | + | 243 | WP_053390218.1 | conjugal transfer protein TrbE | - |
| LH404_RS28710 | 119900..120226 | + | 327 | WP_053390219.1 | hypothetical protein | - |
| LH404_RS28715 | 120247..120999 | + | 753 | WP_053390220.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| LH404_RS28720 | 121010..121246 | + | 237 | WP_053390221.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| LH404_RS28725 | 121221..121781 | + | 561 | WP_039698500.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| LH404_RS28730 | 121768..123138 | + | 1371 | WP_075606918.1 | conjugal transfer pilus assembly protein TraH | - |
| LH404_RS28735 | 123138..126017 | + | 2880 | WP_064386194.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| LH404_RS28740 | 126034..126702 | + | 669 | WP_128317877.1 | hypothetical protein | - |
| LH404_RS28745 | 127061..127792 | + | 732 | WP_064386198.1 | conjugal transfer complement resistance protein TraT | - |
| LH404_RS28750 | 127984..128676 | + | 693 | WP_202395549.1 | hypothetical protein | - |
| LH404_RS28755 | 128795..131113 | + | 2319 | WP_075606915.1 | type IV conjugative transfer system coupling protein TraD | - |
| LH404_RS28760 | 131113..136371 | + | 5259 | WP_075606914.1 | Multifunctional conjugation protein TraI | Relaxase |
| LH404_RS28765 | 136454..137179 | + | 726 | WP_064386205.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| LH404_RS28770 | 137336..137926 | + | 591 | WP_009651737.1 | fertility inhibition protein FinO | - |
| LH404_RS28775 | 138076..138867 | + | 792 | WP_075606913.1 | DsbA family protein | - |
| LH404_RS28780 | 138997..139593 | + | 597 | WP_042927543.1 | PIN domain-containing protein | - |
| LH404_RS28785 | 139663..140307 | + | 645 | WP_042927545.1 | hypothetical protein | - |
| LH404_RS28790 | 140363..140923 | + | 561 | Protein_155 | DUF2726 domain-containing protein | - |
| LH404_RS28795 | 140986..141552 | + | 567 | WP_052544827.1 | Phospholipase D | VF |
| LH404_RS28800 | 141685..141951 | + | 267 | WP_042927547.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|