NZ_CP0842061..138128

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 138128 bp
Accession: NZ_CP084206        Location: 1..138128         Organism: Escherichia coli strain EC2648-R1       Replicon: plasmid pKPC-fusion


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LDB14_RS22330 (1) 1..348 + 348 WP_001139329.1 hypothetical protein -
LDB14_RS22335 (341) 341..1918 + 1578 WP_001001035.1 type IV secretion system DNA-binding domain-containing protein -
LDB14_RS22340 (1921) 1921..4830 + 2910 WP_000932317.1 Multifunctional conjugation protein TraI Relaxase
LDB14_RS22345 (5108) 5108..5302 - 195 WP_000529710.1 hypothetical protein -
LDB14_RS22350 (5314) 5314..5796 - 483 WP_036896345.1 GNAT family protein -
LDB14_RS22355 (5809) 5809..6363 - 555 WP_000616063.1 Phospholipase D VF
LDB14_RS22360 (6326) 6326..7357 - 1032 WP_000138004.1 Type IV secretion system protein VirB11 VF
LDB14_RS22365 (7350) 7350..8504 - 1155 WP_001224296.1 Protein virB10 VF
LDB14_RS22370 (8501) 8501..9388 - 888 WP_000744355.1 Type IV secretion system protein virB9 VF
LDB14_RS22375 (9391) 9391..10107 - 717 WP_000914645.1 Type IV secretion system protein virB8 VF
LDB14_RS22380 (10110) 10110..10280 - 171 WP_021536809.1 hypothetical protein -
LDB14_RS22385 (10375) 10375..11382 - 1008 WP_159108533.1 type IV secretion system protein -
LDB14_RS22390 (11437) 11437..11673 - 237 WP_000733633.1 EexN family lipoprotein -
LDB14_RS22395 (11677) 11677..12384 - 708 WP_000751606.1 Type IV secretion system protein virB5 VF
LDB14_RS22400 (12394) 12394..14667 - 2274 WP_231225962.1 Type IV secretion system protein virB4 VF
LDB14_RS22405 (15024) 15024..15338 - 315 WP_001053888.1 hypothetical protein VF
LDB14_RS22410 (15388) 15388..15678 - 291 WP_001090269.1 hypothetical protein VF
LDB14_RS22415 (15662) 15662..15979 - 318 WP_001267114.1 hypothetical protein -
LDB14_RS22420 (16002) 16002..16742 - 741 WP_000815895.1 Type IV secretion system protein virB1 VF
LDB14_RS22425 (16805) 16805..17041 + 237 WP_000089855.1 H-NS histone family protein -
LDB14_RS22430 (17053) 17053..17400 + 348 WP_250681314.1 hypothetical protein -
LDB14_RS22435 (17434) 17434..18131 + 698 WP_223174630.1 IS1 family transposase ISKpn14 Transposase
LDB14_RS22440 (18160) 18160..18432 + 273 Protein_22 IS5 family transposase ISPan1 Transposase
LDB14_RS22445 (18712) 18712..19716 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
LDB14_RS22450 (19795) 19795..20229 - 435 WP_000429836.1 IS607 family transposase ISChh1 Transposase
LDB14_RS22455 (20301) 20301..20651 + 351 WP_001294663.1 mercuric transport protein MerT -
LDB14_RS22460 (20665) 20665..20940 + 276 WP_000732292.1 mercury resistance system periplasmic binding protein MerP -
LDB14_RS22465 (20976) 20976..21398 + 423 WP_001340589.1 organomercurial transporter MerC -
LDB14_RS22470 (21450) 21450..23144 + 1695 WP_000105636.1 mercury(II) reductase -
LDB14_RS22475 (23162) 23162..23524 + 363 WP_001277456.1 mercury resistance co-regulator MerD -
LDB14_RS22480 (23521) 23521..23757 + 237 WP_000993386.1 broad-spectrum mercury transporter MerE -
LDB14_RS22485 (23793) 23793..24461 + 669 WP_001300294.1 putative signaling protein VF
LDB14_RS22490 (24536) 24536..25708 + 1173 Protein_32 transposase -
LDB14_RS22495 (25773) 25773..26477 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB14_RS22500 (26529) 26529..26990 + 462 Protein_34 Tn3 family transposase TnpR_Tn3 Transposase
LDB14_RS22505 (27113) 27113..28093 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
LDB14_RS22510 (28369) 28369..29250 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
LDB14_RS22515 (29500) 29500..30381 - 882 Protein_37 IS1182 family transposase ISKpn6 Transposase
LDB14_RS22520 (30485) 30485..30781 - 297 WP_013213987.1 transcriptional regulator -
LDB14_RS22525 (30827) 30827..30982 - 156 WP_013213988.1 hypothetical protein -
LDB14_RS22530 (31110) 31110..31535 - 426 WP_013213989.1 antirestriction protein -
LDB14_RS22535 (31646) 31646..31924 - 279 WP_013213990.1 hypothetical protein -
LDB14_RS22540 (32458) 32458..33075 - 618 Protein_42 replication protein -
LDB14_RS22545 (33467) 33467..34027 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
LDB14_RS22550 (34031) 34031..36997 + 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
LDB14_RS22555 (37033) 37033..37101 - 69 Protein_45 IS6 family transposase -
LDB14_RS22560 (37238) 37238..38098 + 861 WP_004176269.1 Beta-lactamase SHV-1 ARG
LDB14_RS22565 (38119) 38119..38880 - 762 WP_002210513.1 DeoR/GlpR family DNA-binding transcription regulator -
LDB14_RS22570 (39141) 39141..40043 + 903 WP_002903955.1 NAD(P)-dependent oxidoreductase -
LDB14_RS22575 (40055) 40055..41307 + 1253 Protein_49 four-carbon acid sugar kinase family protein -
LDB14_RS22580 (41300) 41300..41623 + 324 Protein_50 class II aldolase/adducin family protein -
LDB14_RS22585 (41677) 41677..42381 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB14_RS22590 (42445) 42445..42705 - 261 Protein_52 chemotaxis protein -
LDB14_RS22595 (42768) 42768..43472 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB14_RS22600 (43506) 43506..48641 - 5136 WP_071177725.1 Multifunctional conjugation protein TraI Relaxase
LDB14_RS22605 (48641) 48641..50857 - 2217 WP_059274178.1 type IV conjugative transfer system coupling protein TraD -
LDB14_RS22610 (50908) 50908..51645 - 738 WP_015059020.1 hypothetical protein -
LDB14_RS22615 (51848) 51848..52579 - 732 WP_021559024.1 conjugal transfer complement resistance protein TraT -
LDB14_RS22620 (52604) 52604..53125 - 522 WP_000632668.1 conjugal transfer entry exclusion protein TraS -
LDB14_RS22625 (53158) 53158..55974 - 2817 WP_015059018.1 conjugal transfer mating-pair stabilization protein TraG -
LDB14_RS22630 (55971) 55971..57344 - 1374 WP_000944325.1 conjugal transfer pilus assembly protein TraH -
LDB14_RS22635 (57331) 57331..57723 - 393 WP_000126338.1 F-type conjugal transfer protein TrbF -
LDB14_RS22640 (57677) 57677..57991 - 315 WP_001384255.1 P-type conjugative transfer protein TrbJ -
LDB14_RS22645 (57981) 57981..58526 - 546 WP_000059817.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
LDB14_RS22650 (58513) 58513..58749 - 237 WP_000270010.1 type-F conjugative transfer system pilin chaperone TraQ -
LDB14_RS22655 (58910) 58910..59653 - 744 WP_015059017.1 type-F conjugative transfer system pilin assembly protein TraF -
LDB14_RS22660 (59646) 59646..59903 - 258 WP_053913405.1 conjugal transfer protein TrbE -
LDB14_RS22665 (59930) 59930..61171 - 1242 Protein_67 type-F conjugative transfer system mating-pair stabilization protein TraN -
LDB14_RS22670 (61224) 61224..61928 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB14_RS22675 (62208) 62208..63176 - 969 WP_013362812.1 IS5 family transposase IS903B Transposase
LDB14_RS22680 (63211) 63211..64086 - 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
LDB14_RS22685 (64336) 64336..64527 - 192 Protein_71 IS1380 family transposase -
LDB14_RS22690 (64597) 64597..65301 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB14_RS22695 (65367) 65367..65912 + 546 Protein_73 Tn3 family transposase TnpA_Tn3 Transposase
LDB14_RS22700 (65948) 65948..66363 - 416 Protein_74 IS1-like element IS1B family transposase -
LDB14_RS22705 (66612) 66612..67013 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
LDB14_RS22710 (66946) 66946..67203 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
LDB14_RS22715 (67296) 67296..67949 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
LDB14_RS22720 (68888) 68888..69745 - 858 WP_032495102.1 incFII family plasmid replication initiator RepA -
LDB14_RS23385 (69738) 69738..69812 - 75 WP_001375168.1 RepA leader peptide Tap -
LDB14_RS22730 (70057) 70057..70305 - 249 WP_000083837.1 replication regulatory protein RepA -
LDB14_RS22735 (70589) 70589..70738 - 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
- (70783) 70783..70842 + 60 NuclAT_0 - Antitoxin Detail
- (70783) 70783..70842 + 60 NuclAT_0 - Antitoxin Detail
- (70783) 70783..70842 + 60 NuclAT_0 - Antitoxin Detail
- (70783) 70783..70842 + 60 NuclAT_0 - Antitoxin Detail
LDB14_RS22740 (71437) 71437..72036 - 600 WP_032083981.1 PIN domain-containing protein -
LDB14_RS22745 (72422) 72422..72622 - 201 WP_015059022.1 hypothetical protein -
LDB14_RS22750 (72754) 72754..73314 - 561 WP_000139328.1 fertility inhibition protein FinO -
LDB14_RS22755 (73369) 73369..74115 - 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
LDB14_RS22760 (74135) 74135..74335 - 201 WP_072354025.1 hypothetical protein -
LDB14_RS22765 (74360) 74360..75064 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
LDB14_RS22770 (75119) 75119..75484 - 366 Protein_88 type IV conjugative transfer system protein TraE -
LDB14_RS22775 (75504) 75504..75809 - 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
LDB14_RS22780 (75823) 75823..76191 - 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
LDB14_RS22785 (76253) 76253..76459 - 207 WP_171773970.1 TraY domain-containing protein -
LDB14_RS22790 (76574) 76574..77311 - 738 WP_154244330.1 conjugal transfer protein TrbJ -
LDB14_RS22795 (77511) 77511..77927 - 417 WP_014343494.1 conjugal transfer relaxosome DNA-binding protein TraM -
LDB14_RS22800 (78318) 78318..78803 + 486 WP_014343495.1 hypothetical protein VF
LDB14_RS22805 (78836) 78836..79165 - 330 WP_013214015.1 DUF5983 family protein -
LDB14_RS22810 (79198) 79198..80019 - 822 WP_004152492.1 DUF932 domain-containing protein -
LDB14_RS22815 (80848) 80848..80952 - 105 Protein_97 transcriptional regulator -
LDB14_RS22820 (80956) 80956..81234 - 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
LDB14_RS22825 (81224) 81224..81544 - 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
LDB14_RS22830 (81625) 81625..81849 - 225 WP_014343499.1 hypothetical protein -
LDB14_RS22835 (81860) 81860..82072 - 213 WP_014343500.1 hypothetical protein -
LDB14_RS22840 (82133) 82133..82489 - 357 WP_014343501.1 hypothetical protein -
LDB14_RS22845 (83330) 83330..83647 - 318 WP_014343505.1 hypothetical protein -
LDB14_RS22850 (83662) 83662..84012 - 351 WP_040245917.1 hypothetical protein -
LDB14_RS22855 (84009) 84009..84281 - 273 WP_040245921.1 hypothetical protein -
LDB14_RS22860 (84974) 84974..85072 - 99 WP_159224797.1 Hok/Gef family protein -
LDB14_RS22865 (85047) 85047..85103 - 57 Protein_107 modulator protein -
LDB14_RS22870 (85204) 85204..86277 + 1074 WP_013609528.1 IS481 family transposase ISKpn28 Transposase
LDB14_RS22875 (86461) 86461..86835 - 375 WP_014343510.1 hypothetical protein -
LDB14_RS22880 (86891) 86891..87217 - 327 WP_013023807.1 hypothetical protein -
LDB14_RS22885 (87214) 87214..87942 - 729 WP_001568058.1 plasmid SOS inhibition protein A -
LDB14_RS22890 (87939) 87939..88370 - 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
LDB14_RS22895 (88415) 88415..90472 - 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
LDB14_RS22900 (90542) 90542..90790 - 249 WP_001568055.1 DUF905 domain-containing protein -
LDB14_RS22905 (90839) 90839..91381 - 543 WP_014343512.1 single-stranded DNA-binding protein -
LDB14_RS22910 (92214) 92214..92777 - 564 WP_014343514.1 methyltransferase -
LDB14_RS22915 (92825) 92825..94180 - 1356 WP_014343515.1 DUF3560 domain-containing protein -
LDB14_RS22920 (94232) 94232..94462 - 231 WP_001568051.1 hypothetical protein -
LDB14_RS22925 (94554) 94554..94781 - 228 WP_001568050.1 hypothetical protein -
LDB14_RS22930 (95461) 95461..95781 - 321 WP_001568049.1 hypothetical protein -
LDB14_RS22935 (95816) 95816..96070 - 255 WP_011977779.1 DNA polymerase III subunit theta -
LDB14_RS22940 (96258) 96258..96449 - 192 WP_001568047.1 hypothetical protein -
LDB14_RS22945 (96492) 96492..96998 - 507 WP_013214014.1 antirestriction protein ArdA -
LDB14_RS22950 (97041) 97041..97469 - 429 WP_001568045.1 antirestriction protein -
LDB14_RS22955 (98150) 98150..98917 - 768 WP_013214013.1 hypothetical protein -
LDB14_RS22960 (98971) 98971..99390 - 420 WP_001568043.1 DUF1380 domain-containing protein -
LDB14_RS22965 (99400) 99400..99621 - 222 WP_001568042.1 hypothetical protein -
LDB14_RS22970 (99621) 99621..100322 - 702 WP_001568041.1 DNA methylase -
LDB14_RS22975 (100394) 100394..100563 - 170 Protein_129 hypothetical protein -
LDB14_RS22980 (100759) 100759..100989 - 231 WP_001568040.1 hypothetical protein -
LDB14_RS22985 (101052) 101052..101723 - 672 WP_013214012.1 plasmid partitioning/stability family protein -
LDB14_RS22990 (101726) 101726..102697 - 972 WP_004152353.1 plasmid segregation protein ParM -
LDB14_RS22995 (102946) 102946..104433 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
LDB14_RS23000 (104840) 104840..105271 + 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
LDB14_RS23005 (105271) 105271..106542 + 1272 WP_013214011.1 Y-family DNA polymerase -
LDB14_RS23010 (106624) 106624..107598 - 975 WP_011977819.1 ParB family protein -
LDB14_RS23015 (107598) 107598..108803 - 1206 WP_011977818.1 AAA family ATPase -
LDB14_RS23020 (109913) 109913..110779 - 867 WP_004118283.1 replication initiation protein -
LDB14_RS23025 (111315) 111315..111428 + 114 WP_014343462.1 hypothetical protein -
LDB14_RS23030 (111557) 111557..111814 + 258 WP_013214010.1 hypothetical protein -
LDB14_RS23035 (111860) 111860..112639 - 780 WP_013214009.1 site-specific integrase -
LDB14_RS23040 (112823) 112823..113827 - 1005 WP_011977814.1 hypothetical protein -
LDB14_RS23045 (113857) 113857..114060 - 204 WP_011977813.1 hypothetical protein -
LDB14_RS23050 (114106) 114106..114627 - 522 WP_013214008.1 hypothetical protein -
LDB14_RS23055 (114685) 114685..115077 - 393 WP_011977811.1 hypothetical protein -
LDB14_RS23060 (115114) 115114..116058 - 945 WP_011977810.1 hypothetical protein -
LDB14_RS23065 (116219) 116219..116680 - 462 WP_014343465.1 hypothetical protein -
LDB14_RS23070 (116637) 116637..116867 + 231 WP_001261282.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
LDB14_RS23075 (116864) 116864..117280 + 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
LDB14_RS23080 (117354) 117354..118916 + 1563 WP_004206609.1 AAA family ATPase -
LDB14_RS23085 (118901) 118901..119923 + 1023 WP_000361404.1 helicase UvrD -
LDB14_RS23090 (120179) 120179..120876 + 698 WP_223174630.1 IS1 family transposase ISKpn14 Transposase
LDB14_RS23095 (121018) 121018..121335 + 318 WP_001226231.1 TrbM/KikA/MpfK family conjugal transfer protein -
LDB14_RS23100 (121338) 121338..121652 + 315 WP_000851068.1 hypothetical protein -
LDB14_RS23105 (121628) 121628..122353 + 726 WP_015345246.1 restriction endonuclease -
LDB14_RS23110 (122519) 122519..122755 + 237 WP_049824326.1 Hha/YmoA family nucleoid-associated regulatory protein -
LDB14_RS23115 (122815) 122815..123129 - 315 WP_001280992.1 hypothetical protein -
LDB14_RS23120 (123155) 123155..123481 - 327 WP_000817647.1 endoribonuclease MazF -
LDB14_RS23125 (123471) 123471..123767 - 297 WP_226331936.1 hypothetical protein -
LDB14_RS23130 (123737) 123737..124279 - 543 WP_000711249.1 hypothetical protein -
LDB14_RS23135 (124279) 124279..124524 - 246 WP_000195442.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
LDB14_RS23140 (124986) 124986..125408 + 423 WP_000838908.1 hypothetical protein -
LDB14_RS23145 (125408) 125408..125992 + 585 WP_000690619.1 Tn3 family transposase TnpR_TnShfr1 Transposase
LDB14_RS23150 (126025) 126025..126912 + 888 WP_000130255.1 replication protein RepA -
LDB14_RS23155 (127666) 127666..128085 + 420 WP_052124776.1 DUF192 domain-containing protein -
LDB14_RS23160 (128709) 128709..128978 + 270 WP_000779465.1 hypothetical protein -
LDB14_RS23165 (129067) 129067..129282 + 216 WP_000111575.1 hypothetical protein -
LDB14_RS23170 (129470) 129470..130297 + 828 WP_024147850.1 DUF932 domain-containing protein -
LDB14_RS23175 (130355) 130355..130834 + 480 WP_060628166.1 single-stranded DNA-binding protein -
LDB14_RS23180 (130902) 130902..131204 + 303 WP_000257688.1 TrfB-related DNA-binding protein -
LDB14_RS23185 (131912) 131912..132334 + 423 WP_021536823.1 hypothetical protein -
LDB14_RS23190 (133230) 133230..133370 + 141 WP_153302164.1 hypothetical protein -
LDB14_RS23195 (133722) 133722..134009 + 288 WP_001098466.1 hypothetical protein -
LDB14_RS23200 (134064) 134064..134306 + 243 WP_060628106.1 hypothetical protein -
LDB14_RS23205 (134459) 134459..134614 + 156 WP_021536821.1 hypothetical protein -
LDB14_RS23210 (134687) 134687..134944 + 258 WP_021536820.1 hypothetical protein -
LDB14_RS23215 (134949) 134949..135137 + 189 WP_001001010.1 hypothetical protein -
LDB14_RS23220 (135177) 135177..135947 - 771 WP_000586559.1 SprT-like domain-containing protein -
LDB14_RS23225 (136161) 136161..136529 - 369 WP_000414914.1 plasmid stabilization protein StbC -
LDB14_RS23230 (136531) 136531..137241 - 711 WP_000686338.1 StbB family protein -
LDB14_RS23235 (137254) 137254..137697 - 444 WP_024249956.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance