MGE detailed information
MGE type: IScluster/Tn MGE length: 59688 bp
Accession: NZ_CP083867 Location: 4113..63800 Organism: Escherichia coli strain NDM6 Replicon: plasmid unnamed1
Accession: NZ_CP083867 Location: 4113..63800 Organism: Escherichia coli strain NDM6 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LCE24_RS00005 (3) | 3..715 | - | 713 | Protein_0 | Tn3 family transposase | - |
| LCE24_RS00010 (710) | 710..1109 | + | 400 | Protein_1 | cysteine hydrolase | - |
| LCE24_RS00015 (1248) | 1248..2130 | + | 883 | Protein_2 | EamA family transporter | - |
| LCE24_RS00020 (2162) | 2162..3018 | - | 857 | Protein_3 | TCR/Tet family MFS transporter | - |
| LCE24_RS00025 (3145) | 3145..3797 | + | 653 | Protein_4 | tetracycline resistance transcriptional repressor TetR(A) | - |
| LCE24_RS00030 (3829) | 3829..4071 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| LCE24_RS00035 (4113) | 4113..5863 | - | 1751 | Protein_6 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| LCE24_RS00040 (5858) | 5858..6258 | + | 401 | Protein_7 | cysteine hydrolase | - |
| LCE24_RS00045 (6396) | 6396..7281 | + | 886 | Protein_8 | EamA family transporter | - |
| LCE24_RS00050 (7313) | 7313..8516 | - | 1204 | Protein_9 | tetracycline efflux MFS transporter Tet(A) | - |
| LCE24_RS00055 (8622) | 8622..9272 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| LCE24_RS00060 (9304) | 9304..9552 | - | 249 | WP_224452706.1 | relaxase | - |
| LCE24_RS00065 (9594) | 9594..11347 | - | 1754 | Protein_12 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| LCE24_RS00070 (11351) | 11351..11743 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| LCE24_RS00075 (11881) | 11881..12765 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| LCE24_RS00080 (12797) | 12797..13998 | - | 1202 | Protein_15 | Tetracycline resistance protein, class C | ARG |
| LCE24_RS00085 (14104) | 14104..14754 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| LCE24_RS00090 (14786) | 14786..15036 | - | 251 | Protein_17 | relaxase | - |
| LCE24_RS00095 (15078) | 15078..16829 | - | 1752 | Protein_18 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| LCE24_RS00100 (16824) | 16824..17210 | + | 387 | Protein_19 | cysteine hydrolase | - |
| LCE24_RS00105 (17362) | 17362..18249 | + | 888 | WP_224452705.1 | EamA family transporter | - |
| LCE24_RS00110 (18281) | 18281..19480 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| LCE24_RS00115 (19586) | 19586..20236 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| LCE24_RS00120 (20268) | 20268..20510 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| LCE24_RS00125 (20552) | 20552..22301 | - | 1750 | Protein_24 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| LCE24_RS00130 (22305) | 22305..22697 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| LCE24_RS00135 (22835) | 22835..23719 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| LCE24_RS00140 (23751) | 23751..24949 | - | 1199 | Protein_27 | Tetracycline resistance protein, class C | ARG |
| LCE24_RS00145 (25055) | 25055..25705 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| LCE24_RS00150 (25735) | 25735..25977 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| LCE24_RS00155 (26019) | 26019..27770 | - | 1752 | Protein_30 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| LCE24_RS00160 (27774) | 27774..28166 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| LCE24_RS00165 (28304) | 28304..29188 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| LCE24_RS00170 (29220) | 29220..30418 | - | 1199 | Protein_33 | Tetracycline resistance protein, class C | ARG |
| LCE24_RS00175 (30524) | 30524..31174 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| LCE24_RS00180 (31206) | 31206..31448 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| LCE24_RS00185 (31490) | 31490..33241 | - | 1752 | Protein_36 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| LCE24_RS00190 (33245) | 33245..33637 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| LCE24_RS00195 (33775) | 33775..34658 | + | 884 | Protein_38 | EamA family transporter | - |
| LCE24_RS00200 (34690) | 34690..35891 | - | 1202 | Protein_39 | Tetracycline resistance protein, class C | ARG |
| LCE24_RS00205 (35997) | 35997..36647 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| LCE24_RS00210 (36679) | 36679..36921 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| LCE24_RS00215 (36963) | 36963..38477 | - | 1515 | Protein_42 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| LCE24_RS00220 (38543) | 38543..39247 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LCE24_RS00225 (39391) | 39391..39945 | + | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| LCE24_RS00230 (40076) | 40076..40906 | + | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| LCE24_RS00235 (41044) | 41044..41484 | + | 441 | Protein_46 | CatB-related O-acetyltransferase | - |
| LCE24_RS00240 (41538) | 41538..42242 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LCE24_RS00245 (42308) | 42308..42595 | + | 288 | Protein_48 | IS1380 family transposase ISEcp1 | Transposase |
| LCE24_RS00250 (42851) | 42851..43726 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| LCE24_RS00255 (43773) | 43773..44105 | - | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| LCE24_RS00260 (44131) | 44131..46350 | + | 2220 | Protein_51 | Tn3 family transposase TnpA_Tn3 | Transposase |
| LCE24_RS00265 (46427) | 46427..47131 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LCE24_RS00270 (47183) | 47183..47647 | + | 465 | Protein_53 | IS6 family transposase IS6100 | Transposase |
| LCE24_RS00275 (48140) | 48140..48724 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| LCE24_RS00280 (48724) | 48724..49962 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| LCE24_RS00285 (49959) | 49959..50873 | - | 915 | WP_023063803.1 | hypothetical protein | ARG |
| LCE24_RS00290 (50995) | 50995..51699 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LCE24_RS00295 (51864) | 51864..52157 | + | 294 | Protein_58 | IS30 family transposase | - |
| LCE24_RS00300 (52258) | 52258..53070 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| LCE24_RS00305 (53074) | 53074..53439 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| LCE24_RS00310 (53444) | 53444..54082 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| LCE24_RS00315 (54093) | 54093..54650 | - | 558 | Protein_62 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| LCE24_RS00320 (54750) | 54750..55124 | - | 375 | Protein_63 | protein-disulfide reductase DsbD family protein | - |
| LCE24_RS00325 (55437) | 55437..56978 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| LCE24_RS00330 (57383) | 57383..58222 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| LCE24_RS00335 (58216) | 58216..58563 | - | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| LCE24_RS00340 (58680) | 58680..59518 | - | 839 | Protein_67 | Streptomycin 3''-adenylyltransferase | ARG |
| LCE24_RS00345 (59524) | 59524..59814 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| LCE24_RS00350 (59926) | 59926..60423 | - | 498 | WP_001083725.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | - |
| LCE24_RS00355 (60568) | 60568..61434 | + | 867 | Protein_70 | IS91 family transposase ISAzo26 | Transposase |
| LCE24_RS00360 (61489) | 61489..62193 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| LCE24_RS00365 (62748) | 62748..63032 | + | 285 | WP_001387467.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| LCE24_RS00370 (63032) | 63032..63307 | + | 276 | WP_000421272.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| LCE24_RS00380 (64190) | 64190..64393 | + | 204 | Protein_75 | hypothetical protein | - |
| LCE24_RS00385 (64518) | 64518..64646 | - | 129 | Protein_76 | IS481 family transposase | - |
| LCE24_RS00390 (64679) | 64679..65848 | - | 1170 | WP_001072355.1 | hypothetical protein | - |
| LCE24_RS00395 (66380) | 66380..66648 | + | 269 | Protein_78 | type II toxin-antitoxin system ParD family antitoxin | - |
| LCE24_RS00400 (66635) | 66635..66924 | + | 290 | Protein_79 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LCE24_RS00405 (66991) | 66991..67173 | + | 183 | WP_042344623.1 | hypothetical protein | - |
| LCE24_RS00410 (67294) | 67294..68034 | + | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|