MGE detailed information
MGE type: Conjugative plasmid MGE length: 137856 bp
Accession: NZ_CP083034 Location: 1..137856 Organism: Klebsiella pneumoniae strain 5208.51 Replicon: plasmid p2-5208.51-NDM1
Accession: NZ_CP083034 Location: 1..137856 Organism: Klebsiella pneumoniae strain 5208.51 Replicon: plasmid p2-5208.51-NDM1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K9F36_RS26540 (K9F36_26520) | 19..894 | + | 876 | WP_004098982.1 | replication initiation protein | - |
| K9F36_RS26545 (K9F36_26525) | 1543..2169 | + | 627 | WP_004197649.1 | Chromosome-partitioning ATPase Soj | VF |
| K9F36_RS26550 | 2166..2468 | + | 303 | WP_004197636.1 | hypothetical protein | - |
| K9F36_RS26555 (K9F36_26535) | 2956..3750 | - | 795 | WP_015632375.1 | site-specific integrase | - |
| K9F36_RS26560 (K9F36_26540) | 3743..3904 | - | 162 | WP_032495756.1 | hypothetical protein | - |
| K9F36_RS26565 (K9F36_26545) | 3948..4952 | - | 1005 | WP_016162067.1 | hypothetical protein | - |
| K9F36_RS26570 (K9F36_26550) | 5017..5328 | - | 312 | WP_024191724.1 | hypothetical protein | - |
| K9F36_RS26575 (K9F36_26555) | 5377..5691 | - | 315 | WP_015632378.1 | hypothetical protein | - |
| K9F36_RS26580 (K9F36_26560) | 6223..6816 | + | 594 | WP_123806157.1 | hypothetical protein | - |
| K9F36_RS26585 (K9F36_26565) | 6957..7985 | + | 1029 | WP_046181610.1 | Abi family protein | - |
| K9F36_RS26590 (K9F36_26570) | 8130..10934 | - | 2805 | WP_001568022.1 | hypothetical protein | - |
| K9F36_RS26595 (K9F36_26575) | 11343..11492 | + | 150 | WP_162847634.1 | hypothetical protein | - |
| K9F36_RS26600 (K9F36_26580) | 11519..13111 | - | 1593 | WP_014839879.1 | IS66 family transposase ISKox1 | Transposase |
| K9F36_RS26605 (K9F36_26585) | 13142..13492 | - | 351 | WP_004189161.1 | IS66 family transposase ISKox1 | Transposase |
| K9F36_RS26610 (K9F36_26590) | 13489..13929 | - | 441 | WP_015632382.1 | IS66 family transposase ISKox1 | Transposase |
| K9F36_RS26615 (K9F36_26595) | 14610..15392 | - | 783 | WP_001531258.1 | IS21 family transposase ISSen3 | Transposase |
| K9F36_RS26620 (K9F36_26600) | 15389..16411 | - | 1023 | WP_032441952.1 | IS21 family transposase ISSen3 | Transposase |
| K9F36_RS26625 (K9F36_26605) | 16458..17444 | - | 987 | WP_015632384.1 | AAA family ATPase | - |
| K9F36_RS26630 (K9F36_26610) | 17441..19168 | - | 1728 | WP_001568019.1 | ATP-binding protein | - |
| K9F36_RS26635 (K9F36_26615) | 19614..19862 | + | 249 | WP_001568018.1 | hypothetical protein | - |
| K9F36_RS26640 (K9F36_26620) | 19859..20431 | + | 573 | WP_015632385.1 | hypothetical protein | - |
| K9F36_RS26645 (K9F36_26625) | 20462..20956 | + | 495 | WP_001568016.1 | hypothetical protein | - |
| K9F36_RS26650 (K9F36_26630) | 21189..21539 | - | 351 | WP_167878626.1 | hypothetical protein | - |
| K9F36_RS26655 (K9F36_26635) | 21991..22539 | + | 549 | WP_001567366.1 | thioredoxin fold domain-containing protein | - |
| K9F36_RS26660 (K9F36_26640) | 22586..23020 | + | 435 | WP_001567367.1 | cell envelope integrity protein TolA | - |
| K9F36_RS26665 (K9F36_26645) | 23291..24694 | + | 1404 | WP_001567368.1 | ISNCY family transposase ISKpn21 | Transposase |
| K9F36_RS26670 (K9F36_26650) | 24723..25355 | - | 633 | WP_001567369.1 | hypothetical protein | - |
| K9F36_RS26675 (K9F36_26655) | 25581..26927 | + | 1347 | WP_077253394.1 | ISNCY family transposase ISLad2 | Transposase |
| K9F36_RS26680 (K9F36_26660) | 26976..27371 | + | 396 | WP_015632387.1 | ISNCY family transposase ISKpn21 | Transposase |
| K9F36_RS26685 (K9F36_26665) | 27901..28598 | + | 698 | WP_223335778.1 | IS1 family transposase IS1X2 | Transposase |
| K9F36_RS26690 (K9F36_26670) | 28730..30013 | - | 1284 | WP_015632388.1 | glucose-1-phosphate adenylyltransferase | - |
| K9F36_RS26695 (K9F36_26675) | 30143..32335 | - | 2193 | WP_015632389.1 | 1,4-alpha-glucan branching enzyme | - |
| K9F36_RS26700 (K9F36_26680) | 32708..33676 | + | 969 | WP_004099053.1 | IS5 family transposase IS903B | Transposase |
| K9F36_RS26705 (K9F36_26685) | 33977..34177 | + | 201 | WP_022631502.1 | hypothetical protein | - |
| K9F36_RS26710 (K9F36_26690) | 34592..35596 | - | 1005 | WP_000427623.1 | IS110 family transposase IS4321R | Transposase |
| K9F36_RS26715 (K9F36_26695) | 35675..38641 | - | 2967 | WP_003100881.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| K9F36_RS26720 (K9F36_26700) | 38716..39006 | + | 291 | WP_001247892.1 | nucleotidyltransferase | - |
| K9F36_RS26725 (K9F36_26705) | 39003..39404 | + | 402 | WP_001293886.1 | DUF86 domain-containing protein | - |
| K9F36_RS26730 (K9F36_26710) | 39394..39750 | + | 357 | WP_000215515.1 | cupin domain-containing protein | - |
| K9F36_RS26735 (K9F36_26715) | 40005..40319 | + | 315 | WP_000091613.1 | hypothetical protein | - |
| K9F36_RS26740 (K9F36_26720) | 40746..41927 | - | 1182 | WP_004194048.1 | Na+/H+ antiporter NhaA | - |
| K9F36_RS26745 (K9F36_26725) | 42187..44214 | + | 2028 | WP_004152345.1 | class I SAM-dependent DNA methyltransferase | - |
| K9F36_RS26750 (K9F36_26730) | 44211..45527 | + | 1317 | WP_004152344.1 | restriction endonuclease subunit S | - |
| K9F36_RS26755 (K9F36_26735) | 45528..48785 | + | 3258 | WP_004152343.1 | DEAD/DEAH box helicase family protein | - |
| K9F36_RS26760 (K9F36_26740) | 48790..50058 | + | 1269 | WP_004152342.1 | ISL3 family transposase ISKpn25 | Transposase |
| K9F36_RS26765 | 50624..50716 | + | 93 | Protein_45 | SMR family transporter | - |
| K9F36_RS26770 (K9F36_26745) | 50749..51354 | - | 606 | WP_000509966.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| K9F36_RS26775 (K9F36_26750) | 51449..52624 | + | 1176 | Protein_47 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| K9F36_RS26780 (K9F36_26755) | 52736..55729 | - | 2994 | WP_015632391.1 | Tn3 family transposase TnpA_ISXc4 | Transposase |
| K9F36_RS26785 (K9F36_26760) | 55733..56143 | - | 411 | WP_022631505.1 | putative toxin-antitoxin system toxin component, PIN family | - |
| K9F36_RS26790 (K9F36_26765) | 56143..56382 | - | 240 | WP_023356273.1 | ribbon-helix-helix domain-containing protein | - |
| K9F36_RS26795 (K9F36_26770) | 56725..57489 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| K9F36_RS26800 (K9F36_26775) | 57607..57675 | - | 69 | Protein_52 | EAL domain-containing protein | - |
| K9F36_RS26805 (K9F36_26780) | 57996..58496 | - | 501 | WP_000376623.1 | GNAT family N-acetyltransferase | - |
| K9F36_RS26810 | 58845..58973 | - | 129 | Protein_54 | glutathione S-transferase | - |
| K9F36_RS26815 (K9F36_26790) | 59279..59911 | + | 633 | WP_031281281.1 | Chloramphenicol acetyltransferase | VF |
| K9F36_RS26820 (K9F36_26795) | 60171..61451 | - | 1281 | Protein_56 | IS91 family transposase ISVsa3 | Transposase |
| K9F36_RS26825 (K9F36_26800) | 61453..61548 | - | 96 | Protein_57 | 16S rRNA (guanine(1405)-N(7))-methyltransferase RmtF | - |
| K9F36_RS26830 (K9F36_26805) | 61560..62339 | - | 780 | WP_015632396.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| K9F36_RS26835 (K9F36_26810) | 62362..62520 | - | 159 | Protein_59 | 16S rRNA (guanine(1405)-N(7))-methyltransferase RmtF | - |
| K9F36_RS26840 (K9F36_26815) | 62750..63304 | - | 555 | WP_022631510.1 | AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase | - |
| K9F36_RS26845 (K9F36_26820) | 63923..65278 | + | 1356 | WP_015613264.1 | group II intron reverse transcriptase/maturase | - |
| K9F36_RS26850 (K9F36_26825) | 65359..65811 | - | 453 | WP_000237816.1 | hypothetical protein | ARG |
| K9F36_RS26855 (K9F36_26830) | 65984..66997 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| K9F36_RS26860 (K9F36_26835) | 67172..67333 | - | 162 | WP_023277723.1 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| K9F36_RS26865 (K9F36_26840) | 67440..67688 | + | 249 | WP_012585400.1 | type II toxin-antitoxin system YafQ family toxin | - |
| K9F36_RS26870 (K9F36_26845) | 67815..68390 | + | 576 | WP_001173919.1 | Tn3 family transposase ISPsy42 | Transposase |
| K9F36_RS26875 (K9F36_26850) | 68503..69423 | + | 921 | WP_022631165.1 | Tn3 family transposase TnpR_ISThsp9 | Transposase |
| K9F36_RS26880 (K9F36_26855) | 69466..71007 | - | 1542 | Protein_68 | Tn3 family transposase TnpA_IS3000 | Transposase |
| K9F36_RS26885 (K9F36_26860) | 71150..72409 | - | 1260 | Protein_69 | 60 kDa chaperonin | VF |
| K9F36_RS26890 (K9F36_26865) | 72465..72755 | - | 291 | WP_004201172.1 | co-chaperone GroES | - |
| K9F36_RS26895 (K9F36_26870) | 72949..73278 | + | 330 | WP_004201171.1 | divalent-cation tolerance protein CutA | - |
| K9F36_RS26900 | 73283..73657 | + | 375 | Protein_72 | protein-disulfide reductase DsbD family protein | - |
| K9F36_RS26905 | 73757..74314 | + | 558 | Protein_73 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| K9F36_RS26910 (K9F36_26880) | 74325..74963 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| K9F36_RS26915 (K9F36_26885) | 74968..75333 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| K9F36_RS26920 (K9F36_26890) | 75337..76149 | - | 813 | WP_004201164.1 | Metallo-beta-lactamase type 2 | ARG |
| K9F36_RS26925 (K9F36_26895) | 76250..76501 | - | 252 | Protein_77 | IS30 family transposase | - |
| K9F36_RS26930 (K9F36_26900) | 76578..79595 | - | 3018 | WP_021740570.1 | Tn3 family transposase TnpA_IS3000 | Transposase |
| K9F36_RS26935 (K9F36_26905) | 79728..81893 | - | 2166 | WP_015632414.1 | class I SAM-dependent DNA methyltransferase | - |
| K9F36_RS26940 (K9F36_26910) | 81905..83635 | - | 1731 | WP_015632415.1 | DUF262 domain-containing protein | - |
| K9F36_RS26945 (K9F36_26915) | 83650..84558 | - | 909 | WP_015632416.1 | WYL domain-containing protein | - |
| K9F36_RS26950 (K9F36_26920) | 84722..85045 | - | 324 | WP_157833877.1 | Tn7-like element transposition protein TnsE | - |
| K9F36_RS26955 (K9F36_26925) | 86145..86846 | - | 702 | WP_157948106.1 | RepA family replication protein | - |
| K9F36_RS26960 (K9F36_26930) | 87230..87616 | - | 387 | WP_015632417.1 | acyl-CoA thioesterase | - |
| K9F36_RS26965 (K9F36_26935) | 87616..88086 | - | 471 | WP_032441927.1 | hypothetical protein | - |
| K9F36_RS26970 (K9F36_26940) | 88068..88646 | - | 579 | WP_015632419.1 | hypothetical protein | - |
| K9F36_RS26975 (K9F36_26945) | 88914..89447 | + | 534 | WP_015632420.1 | transcription termination/antitermination NusG family protein | - |
| K9F36_RS26980 (K9F36_26950) | 89465..89668 | + | 204 | WP_032495743.1 | hypothetical protein | - |
| K9F36_RS26985 (K9F36_26955) | 89702..90013 | + | 312 | WP_015632421.1 | hypothetical protein | - |
| K9F36_RS26990 (K9F36_26960) | 90711..91190 | + | 480 | WP_015632423.1 | hypothetical protein | VF |
| K9F36_RS26995 (K9F36_26965) | 91213..91680 | + | 468 | WP_015632424.1 | DotD/TraH family lipoprotein | - |
| K9F36_RS27000 (K9F36_26970) | 91677..92495 | + | 819 | WP_015632425.1 | hypothetical protein | VF |
| K9F36_RS27005 (K9F36_26975) | 92473..93660 | + | 1188 | WP_032495744.1 | putative protein YggR | VF |
| K9F36_RS27010 (K9F36_26980) | 93657..93923 | + | 267 | WP_032441926.1 | hypothetical protein | VF |
| K9F36_RS27015 (K9F36_26985) | 93941..97264 | + | 3324 | WP_032495745.1 | DNA primase TraC | VF |
| K9F36_RS27020 (K9F36_26990) | 97298..97651 | + | 354 | WP_015632427.1 | hypothetical protein | - |
| K9F36_RS27025 (K9F36_26995) | 97687..98391 | + | 705 | WP_015632428.1 | DotI/IcmL/TraM family protein | - |
| K9F36_RS27030 (K9F36_27000) | 98402..99505 | + | 1104 | WP_015632429.1 | DotH/IcmK family type IV secretion protein | - |
| K9F36_RS27035 (K9F36_27005) | 99509..100849 | + | 1341 | WP_015632430.1 | conjugal transfer protein TraO | - |
| K9F36_RS27040 (K9F36_27010) | 100855..101574 | + | 720 | WP_015632431.1 | conjugal transfer protein TraP | - |
| K9F36_RS27045 (K9F36_27015) | 101584..102117 | + | 534 | WP_015632432.1 | conjugal transfer protein TraQ | - |
| K9F36_RS27050 (K9F36_27020) | 102171..102572 | + | 402 | WP_015632433.1 | hypothetical protein | - |
| K9F36_RS27055 (K9F36_27025) | 102865..103179 | + | 315 | WP_123677146.1 | hypothetical protein | - |
| K9F36_RS27060 (K9F36_27030) | 103189..106236 | + | 3048 | WP_015632435.1 | conjugal transfer protein | - |
| K9F36_RS27065 (K9F36_27035) | 106247..107443 | + | 1197 | WP_015632436.1 | conjugal transfer protein TraW | - |
| K9F36_RS27070 (K9F36_27040) | 107440..108021 | + | 582 | WP_015632437.1 | conjugal transfer protein TraX | - |
| K9F36_RS27075 (K9F36_27045) | 108063..110207 | + | 2145 | WP_015632438.1 | DotA/TraY family protein | - |
| K9F36_RS27080 (K9F36_27050) | 110273..110896 | + | 624 | WP_015632439.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| K9F36_RS27085 (K9F36_27055) | 110998..112416 | + | 1419 | WP_015632440.1 | hypothetical protein | - |
| K9F36_RS27090 (K9F36_27060) | 112427..113518 | + | 1092 | WP_050484136.1 | thioredoxin fold domain-containing protein | - |
| K9F36_RS27095 (K9F36_27065) | 113520..115712 | + | 2193 | WP_015632442.1 | hypothetical protein | VF |
| K9F36_RS27100 (K9F36_27070) | 115758..116063 | + | 306 | WP_015632443.1 | phospholipase D-like domain-containing protein | - |
| K9F36_RS27105 (K9F36_27075) | 116086..117675 | - | 1590 | WP_015632444.1 | IS66 family transposase ISEcl6 | Transposase |
| K9F36_RS27110 (K9F36_27080) | 117705..118054 | - | 350 | Protein_114 | IS66 family transposase IS682 | Transposase |
| K9F36_RS27115 (K9F36_27085) | 118051..118458 | - | 408 | WP_015632445.1 | IS66 family transposase ISCro1 | Transposase |
| K9F36_RS27120 (K9F36_27090) | 118513..118791 | + | 279 | WP_223351478.1 | Phospholipase D | VF |
| K9F36_RS27125 (K9F36_27095) | 118803..119054 | + | 252 | WP_016162080.1 | hypothetical protein | - |
| K9F36_RS27130 (K9F36_27100) | 119095..121023 | - | 1929 | WP_015632446.1 | Protein TraI | Relaxase |
| K9F36_RS27135 (K9F36_27105) | 121026..121337 | - | 312 | WP_016162079.1 | plasmid mobilization protein MobA | - |
| K9F36_RS27140 (K9F36_27110) | 121733..122065 | + | 333 | WP_015632448.1 | hypothetical protein | - |
| K9F36_RS27145 (K9F36_27115) | 122336..122656 | - | 321 | WP_015632449.1 | hypothetical protein | - |
| K9F36_RS27150 (K9F36_27120) | 122710..122943 | - | 234 | WP_016162076.1 | hypothetical protein | - |
| K9F36_RS27155 (K9F36_27125) | 123635..124072 | - | 438 | WP_015632450.1 | antirestriction protein | - |
| K9F36_RS27160 (K9F36_27130) | 124242..125102 | - | 861 | WP_015632451.1 | DUF4942 domain-containing protein | - |
| K9F36_RS27165 (K9F36_27135) | 125176..125358 | - | 183 | WP_223351475.1 | cobalamin biosynthesis protein CbiX | - |
| K9F36_RS27170 (K9F36_27140) | 125499..125858 | - | 360 | WP_016162075.1 | hypothetical protein | - |
| K9F36_RS27175 (K9F36_27145) | 126452..126889 | - | 438 | WP_015632453.1 | JAB domain-containing protein | - |
| K9F36_RS27180 (K9F36_27150) | 127017..127505 | - | 489 | WP_015632454.1 | transcriptional regulator | - |
| K9F36_RS27185 (K9F36_27155) | 127502..127960 | - | 459 | WP_015632455.1 | hypothetical protein | - |
| K9F36_RS27190 (K9F36_27160) | 128113..128541 | - | 429 | WP_015632456.1 | plasmid partitioning/stability family protein | - |
| K9F36_RS27195 (K9F36_27165) | 128534..129514 | - | 981 | WP_015632457.1 | plasmid segregation protein ParM | - |
| K9F36_RS27200 (K9F36_27170) | 129875..130057 | + | 183 | WP_015632458.1 | type II toxin-antitoxin system HicA family toxin | - |
| K9F36_RS27205 (K9F36_27175) | 130083..130526 | + | 444 | WP_015632459.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| K9F36_RS27210 (K9F36_27180) | 130732..130854 | - | 123 | Protein_134 | transcriptional regulator | - |
| K9F36_RS27215 (K9F36_27185) | 130868..131095 | - | 228 | WP_016162072.1 | hypothetical protein | - |
| K9F36_RS27220 | 131327..131782 | + | 456 | WP_015632461.1 | helix-turn-helix domain-containing protein | - |
| K9F36_RS27225 | 132034..132129 | - | 96 | Protein_137 | IS1595 family transposase ISNtsp4 | Transposase |
| K9F36_RS27230 (K9F36_27200) | 132594..132971 | - | 378 | WP_016162069.1 | hypothetical protein | - |
| K9F36_RS27235 (K9F36_27205) | 133083..133388 | - | 306 | WP_015632464.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| K9F36_RS27240 (K9F36_27210) | 133388..133606 | - | 219 | WP_015632465.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| K9F36_RS27245 (K9F36_27215) | 133792..134817 | + | 1026 | WP_015632466.1 | IS110 family transposase ISAve1 | Transposase |
| K9F36_RS27250 (K9F36_27220) | 135112..135597 | + | 486 | Protein_142 | IS5 family transposase IS903B | Transposase |
| K9F36_RS27255 (K9F36_27225) | 135761..136192 | + | 432 | WP_015632467.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| K9F36_RS27260 (K9F36_27230) | 136192..137463 | + | 1272 | WP_016162068.1 | Y-family DNA polymerase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|