MGE detailed information
MGE type: Conjugative plasmid MGE length: 136961 bp
Accession: NZ_CP082128 Location: 1..136961 Organism: Escherichia coli strain NDM_12_14482 Replicon: plasmid pIncFIA
Accession: NZ_CP082128 Location: 1..136961 Organism: Escherichia coli strain NDM_12_14482 Replicon: plasmid pIncFIA
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| K5P76_RS23530 (1) | 1..858 | + | 858 | WP_029702152.1 | incFII family plasmid replication initiator RepA | - |
| K5P76_RS23535 (1797) | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| K5P76_RS23540 (2543) | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| K5P76_RS23545 (2733) | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| K5P76_RS23550 (3271) | 3271..6168 | - | 2898 | WP_001553819.1 | Tn3-like element Tn5403 family transposase | - |
| K5P76_RS23555 (6263) | 6263..6868 | + | 606 | WP_000509965.1 | recombinase family protein | - |
| K5P76_RS23560 (6892) | 6892..7641 | - | 750 | Protein_6 | Tn3 family transposase | - |
| K5P76_RS23565 (7645) | 7645..8037 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| K5P76_RS23570 (8175) | 8175..9059 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| K5P76_RS23575 (9091) | 9091..10290 | - | 1200 | WP_000804064.1 | tetracycline efflux MFS transporter Tet(A) | - |
| K5P76_RS23580 (10396) | 10396..11046 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| K5P76_RS23585 (11078) | 11078..11320 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| K5P76_RS23590 (11362) | 11362..12876 | - | 1515 | Protein_12 | Tn3-like element TnAs1 family transposase | - |
| K5P76_RS23595 (12942) | 12942..13646 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| K5P76_RS23600 (13790) | 13790..14344 | + | 555 | WP_063840321.1 | fluoroquinolone-acetylating aminoglycoside 6'-N-acetyltransferase AAC(6')-Ib-cr5 | - |
| K5P76_RS23605 (14475) | 14475..15305 | + | 831 | WP_001334766.1 | oxacillin-hydrolyzing class D beta-lactamase OXA-1 | - |
| K5P76_RS23610 (15443) | 15443..15883 | + | 441 | Protein_16 | CatB-related O-acetyltransferase | - |
| K5P76_RS23615 (15937) | 15937..16641 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| K5P76_RS23620 (16707) | 16707..16994 | + | 288 | Protein_18 | transposase | - |
| K5P76_RS23625 (17250) | 17250..18125 | + | 876 | WP_000239590.1 | extended-spectrum class A beta-lactamase CTX-M-15 | - |
| K5P76_RS23630 (18172) | 18172..18465 | - | 294 | WP_116961751.1 | WbuC family cupin fold metalloprotein | - |
| K5P76_RS23635 (18530) | 18530..20749 | + | 2220 | Protein_21 | Tn3-like element Tn3 family transposase | - |
| K5P76_RS23640 (20826) | 20826..21530 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| K5P76_RS23645 (21585) | 21585..22451 | - | 867 | Protein_23 | class 1 integron integrase IntI1 | - |
| K5P76_RS23650 (22596) | 22596..23093 | + | 498 | WP_001083725.1 | trimethoprim-resistant dihydrofolate reductase DfrA12 | - |
| K5P76_RS23655 (23205) | 23205..23495 | + | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| K5P76_RS23660 (23501) | 23501..24339 | + | 839 | Protein_26 | AadA family aminoglycoside 3''-O-nucleotidyltransferase | - |
| K5P76_RS23665 (24456) | 24456..24803 | + | 348 | WP_000679427.1 | quaternary ammonium compound efflux SMR transporter QacE delta 1 | - |
| K5P76_RS23670 (24797) | 24797..25636 | + | 840 | WP_000259031.1 | sulfonamide-resistant dihydropteroate synthase Sul1 | - |
| K5P76_RS23675 (26041) | 26041..27582 | + | 1542 | WP_000050481.1 | IS91-like element ISCR1 family transposase | - |
| K5P76_RS24525 (27895) | 27895..28269 | + | 375 | Protein_30 | protein-disulfide reductase DsbD family protein | - |
| K5P76_RS24530 (28369) | 28369..28926 | + | 558 | Protein_31 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| K5P76_RS23685 (28937) | 28937..29575 | - | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| K5P76_RS23690 (29580) | 29580..29945 | - | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| K5P76_RS23695 (29949) | 29949..30761 | - | 813 | WP_023408309.1 | subclass B1 metallo-beta-lactamase NDM-5 | - |
| K5P76_RS23700 (30862) | 30862..31155 | - | 294 | Protein_35 | IS30 family transposase | - |
| K5P76_RS23705 (31320) | 31320..32024 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| K5P76_RS23710 (32218) | 32218..32568 | - | 351 | Protein_37 | chaperonin GroEL | - |
| K5P76_RS23715 (32631) | 32631..33179 | + | 549 | WP_014342204.1 | cation:proton antiporter | - |
| K5P76_RS23720 (33260) | 33260..34015 | - | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase RmtB1 | - |
| K5P76_RS23725 (34185) | 34185..35045 | - | 861 | WP_000027057.1 | broad-spectrum class A beta-lactamase TEM-1 | - |
| K5P76_RS23730 (35228) | 35228..35785 | - | 558 | WP_001235713.1 | recombinase family protein | - |
| K5P76_RS23735 (36087) | 36087..36851 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| K5P76_RS23740 (37344) | 37344..37928 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| K5P76_RS23745 (37928) | 37928..39166 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| K5P76_RS23750 (39163) | 39163..40077 | - | 915 | WP_023063803.1 | Mph(A) family macrolide 2'-phosphotransferase | - |
| K5P76_RS23755 (40199) | 40199..40903 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| K5P76_RS23760 (40964) | 40964..43375 | + | 2412 | Protein_47 | Tn3 family transposase | - |
| K5P76_RS23765 (43409) | 43409..43513 | + | 105 | Protein_48 | IS5/IS1182 family transposase | - |
| K5P76_RS23770 (43663) | 43663..44295 | - | 633 | Protein_49 | histidine-type phosphatase | - |
| K5P76_RS23775 (44417) | 44417..44902 | - | 486 | WP_000874189.1 | hypothetical protein | - |
| K5P76_RS23780 (44927) | 44927..45412 | - | 486 | WP_001267176.1 | TlpA disulfide reductase family protein | - |
| K5P76_RS23785 (45399) | 45399..46094 | - | 696 | WP_000117262.1 | ABC transporter ATP-binding protein | - |
| K5P76_RS23790 (46099) | 46099..47229 | - | 1131 | WP_000729219.1 | ABC transporter permease | - |
| K5P76_RS23795 (47219) | 47219..48502 | - | 1284 | WP_000964653.1 | ABC transporter permease | - |
| K5P76_RS23800 (48505) | 48505..49884 | - | 1380 | WP_000119836.1 | Fe-S-containing protein | - |
| K5P76_RS23805 (49988) | 49988..50515 | - | 528 | WP_000178050.1 | iron transporter | - |
| K5P76_RS23810 (50556) | 50556..52442 | - | 1887 | WP_000118029.1 | FTR1 family protein | - |
| K5P76_RS23815 (52789) | 52789..53550 | - | 762 | WP_001225378.1 | Na(+)-translocating NADH-quinone reductase subunit C | - |
| K5P76_RS23820 (53787) | 53787..54293 | - | 507 | WP_000949452.1 | protein disulfide oxidoreductase | - |
| K5P76_RS23825 (54283) | 54283..54453 | - | 171 | Protein_60 | DsbA family protein | - |
| K5P76_RS23830 (54591) | 54591..54704 | - | 114 | Protein_61 | IS6 family transposase | - |
| K5P76_RS23835 (54904) | 54904..55601 | + | 698 | WP_223350503.1 | IS1 family transposase | - |
| K5P76_RS23840 (55751) | 55751..56437 | + | 687 | Protein_63 | IS1 family transposase | - |
| K5P76_RS23845 (56691) | 56691..57713 | - | 1023 | WP_000361402.1 | helicase UvrD | - |
| K5P76_RS23850 (57698) | 57698..59263 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| K5P76_RS23855 (59338) | 59338..59754 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K5P76_RS23860 (59751) | 59751..59981 | - | 231 | WP_001261286.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| K5P76_RS23865 (60541) | 60541..60759 | + | 219 | WP_000813630.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| K5P76_RS23870 (60761) | 60761..61066 | + | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| K5P76_RS23875 (61067) | 61067..61873 | + | 807 | WP_000016970.1 | site-specific integrase | - |
| K5P76_RS23880 (62595) | 62595..63350 | + | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| K5P76_RS23885 (63938) | 63938..65104 | + | 1167 | WP_000772446.1 | plasmid-partitioning protein SopA | - |
| K5P76_RS23890 (65104) | 65104..66075 | + | 972 | WP_000817031.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| K5P76_RS23895 (66813) | 66813..67715 | + | 903 | WP_064766247.1 | DUF1281 domain-containing protein | - |
| K5P76_RS23900 (67712) | 67712..68023 | + | 312 | WP_012615291.1 | hypothetical protein | - |
| K5P76_RS23905 (68100) | 68100..68783 | + | 684 | WP_032181561.1 | DNA methylase | - |
| K5P76_RS23910 (68784) | 68784..69005 | + | 222 | WP_001104873.1 | hypothetical protein | - |
| K5P76_RS23915 (68935) | 68935..69453 | + | 519 | WP_223349485.1 | DUF1380 family protein | - |
| K5P76_RS23920 (69498) | 69498..70268 | + | 771 | WP_001006251.1 | hypothetical protein | - |
| K5P76_RS23925 (70682) | 70682..71107 | + | 426 | WP_001546490.1 | antirestriction protein | - |
| K5P76_RS23930 (71154) | 71154..71576 | + | 423 | WP_000271685.1 | DUF1380 family protein | - |
| K5P76_RS23935 (71573) | 71573..71764 | + | 192 | WP_001027495.1 | hypothetical protein | - |
| K5P76_RS23940 (72077) | 72077..73744 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| K5P76_RS24535 (74473) | 74473..74627 | - | 155 | Protein_84 | hypothetical protein | - |
| K5P76_RS23950 (75144) | 75144..75374 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| K5P76_RS23955 (75426) | 75426..76787 | + | 1362 | WP_039023242.1 | DUF3560 domain-containing protein | - |
| K5P76_RS23960 (76835) | 76835..77398 | + | 564 | WP_029702196.1 | class I SAM-dependent methyltransferase | - |
| K5P76_RS23965 (77484) | 77484..77666 | - | 183 | Protein_88 | pilus protein | - |
| K5P76_RS23970 (77779) | 77779..79446 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| K5P76_RS23975 (81108) | 81108..81677 | - | 570 | WP_089634947.1 | hypothetical protein | - |
| K5P76_RS23985 (82981) | 82981..83739 | + | 759 | Protein_92 | site-specific integrase | - |
| K5P76_RS23990 (83897) | 83897..84907 | + | 1011 | WP_000053332.1 | substrate-binding domain-containing protein | - |
| K5P76_RS23995 (85003) | 85003..87129 | + | 2127 | WP_000253905.1 | alpha-galactosidase | - |
| K5P76_RS24000 (87192) | 87192..88469 | + | 1278 | WP_001083369.1 | MFS transporter | - |
| K5P76_RS24005 (88466) | 88466..89899 | + | 1434 | WP_024170639.1 | glycoside hydrolase family 32 protein | - |
| K5P76_RS24010 (90094) | 90094..91488 | + | 1395 | WP_001037799.1 | carbohydrate porin | - |
| K5P76_RS24015 (91734) | 91734..91838 | - | 105 | Protein_98 | thiosulfate reductase cytochrome B subunit | - |
| K5P76_RS24020 (91895) | 91895..92588 | + | 694 | Protein_99 | IS1 family transposase | - |
| K5P76_RS24025 (92715) | 92715..93227 | + | 513 | WP_223350513.1 | potassium channel family protein | - |
| K5P76_RS24030 (93312) | 93312..93563 | + | 252 | Protein_101 | iron-containing alcohol dehydrogenase | - |
| K5P76_RS24035 (93852) | 93852..94169 | - | 318 | Protein_102 | IS110 family transposase | - |
| K5P76_RS24040 (94324) | 94324..94429 | + | 106 | Protein_103 | plasmid SOS inhibition protein A | - |
| - (94398) | 94398..94596 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (94398) | 94398..94596 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (94398) | 94398..94596 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| - (94398) | 94398..94596 | + | 199 | NuclAT_0 | - | Antitoxin Detail |
| K5P76_RS24540 (94603) | 94603..94752 | + | 150 | Protein_104 | DUF5431 family protein | - |
| K5P76_RS24045 (94703) | 94703..94819 | + | 117 | WP_001375150.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| K5P76_RS24545 (95120) | 95120..95417 | - | 298 | Protein_106 | hypothetical protein | - |
| K5P76_RS24050 (95487) | 95487..95693 | + | 207 | WP_000275854.1 | hypothetical protein | - |
| K5P76_RS24055 (95718) | 95718..96005 | + | 288 | WP_000107242.1 | hypothetical protein | - |
| K5P76_RS24060 (96124) | 96124..96945 | + | 822 | WP_001234465.1 | DUF932 domain-containing protein | - |
| K5P76_RS24065 (97241) | 97241..97813 | - | 573 | WP_000949660.1 | transglycosylase SLT domain-containing protein | - |
| K5P76_RS24070 (98183) | 98183..98566 | + | 384 | WP_001063020.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| K5P76_RS24075 (98757) | 98757..99404 | + | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| K5P76_RS24080 (99540) | 99540..99755 | + | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| K5P76_RS24085 (99798) | 99798..100163 | + | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| K5P76_RS24090 (100178) | 100178..100489 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| K5P76_RS24095 (100511) | 100511..101077 | + | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| K5P76_RS24100 (101064) | 101064..101792 | + | 729 | WP_001230813.1 | type-F conjugative transfer system secretin TraK | - |
| K5P76_RS24105 (101792) | 101792..103219 | + | 1428 | WP_001553836.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| K5P76_RS24110 (103209) | 103209..103799 | + | 591 | WP_000002787.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| K5P76_RS24550 (103786) | 103786..104106 | + | 321 | Protein_120 | conjugal transfer protein TrbD | - |
| K5P76_RS24125 (104099) | 104099..104350 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| K5P76_RS24130 (104347) | 104347..104862 | + | 516 | WP_000809832.1 | type IV conjugative transfer system lipoprotein TraV | - |
| K5P76_RS24135 (104997) | 104997..105218 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| K5P76_RS24140 (105378) | 105378..108005 | + | 2628 | WP_039021964.1 | type IV secretion system protein TraC | - |
| K5P76_RS24145 (108002) | 108002..108388 | + | 387 | WP_000214092.1 | type-F conjugative transfer system protein TrbI | - |
| K5P76_RS24150 (108385) | 108385..109017 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| K5P76_RS24155 (109014) | 109014..110006 | + | 993 | WP_001553833.1 | conjugal transfer pilus assembly protein TraU | - |
| K5P76_RS24160 (110015) | 110015..110653 | + | 639 | WP_001553832.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| K5P76_RS24165 (110650) | 110650..112458 | + | 1809 | WP_039023153.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| K5P76_RS24170 (112485) | 112485..112742 | + | 258 | WP_039023152.1 | conjugal transfer protein TrbE | - |
| K5P76_RS24175 (112735) | 112735..113478 | + | 744 | WP_143212015.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| K5P76_RS24180 (113494) | 113494..113841 | + | 348 | WP_001287894.1 | conjugal transfer protein TrbA | - |
| K5P76_RS24185 (113960) | 113960..114244 | + | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| K5P76_RS24190 (114231) | 114231..114776 | + | 546 | WP_016236310.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| K5P76_RS24195 (114706) | 114706..115068 | + | 363 | WP_071550055.1 | P-type conjugative transfer protein TrbJ | - |
| K5P76_RS24200 (115068) | 115068..116441 | + | 1374 | WP_039023150.1 | conjugal transfer pilus assembly protein TraH | - |
| K5P76_RS24205 (116438) | 116438..119257 | + | 2820 | WP_039023149.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| K5P76_RS24210 (119276) | 119276..119773 | + | 498 | WP_000605862.1 | entry exclusion protein | - |
| K5P76_RS24215 (119805) | 119805..120536 | + | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| K5P76_RS24220 (120789) | 120789..123032 | + | 2244 | WP_094907434.1 | type IV conjugative transfer system coupling protein TraD | - |
| K5P76_RS24225 (123041) | 123041..123439 | - | 399 | WP_039023147.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| K5P76_RS24230 (123439) | 123439..123666 | - | 228 | WP_039023146.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| K5P76_RS24235 (123748) | 123748..129018 | + | 5271 | WP_039023145.1 | conjugative transfer relaxase/helicase TraI | - |
| K5P76_RS24240 (129294) | 129294..130835 | + | 1542 | WP_002431311.1 | IS21-like element ISEc12 family transposase | - |
| K5P76_RS24245 (130850) | 130850..131596 | + | 747 | WP_001016257.1 | IS21-like element ISEc12 family helper ATPase IstB | - |
| K5P76_RS24250 (131624) | 131624..132370 | + | 747 | WP_052273601.1 | conjugal transfer pilus acetylase TraX | - |
| K5P76_RS24255 (132425) | 132425..132985 | + | 561 | WP_001567328.1 | fertility inhibition protein FinO | - |
| K5P76_RS24260 (133116) | 133116..133325 | + | 210 | WP_039023209.1 | hypothetical protein | - |
| K5P76_RS24265 (133737) | 133737..134363 | + | 627 | WP_029702149.1 | NYN domain-containing protein | - |
| K5P76_RS24270 (134515) | 134515..135084 | + | 570 | WP_029702150.1 | DUF2726 domain-containing protein | - |
| K5P76_RS24555 (135297) | 135297..135725 | + | 429 | WP_029702151.1 | hypothetical protein | - |
| - (135864) | 135864..135925 | - | 62 | NuclAT_1 | - | - |
| - (135864) | 135864..135925 | - | 62 | NuclAT_1 | - | - |
| - (135864) | 135864..135925 | - | 62 | NuclAT_1 | - | - |
| - (135864) | 135864..135925 | - | 62 | NuclAT_1 | - | - |
| K5P76_RS24280 (135969) | 135969..136118 | + | 150 | WP_001367749.1 | Hok/Gef family protein | - |
| K5P76_RS24285 (136402) | 136402..136659 | + | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| K5P76_RS24560 (136764) | 136764..136949 | + | 186 | WP_077818652.1 | protein CopA/IncA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|