MGE detailed information

MGE type: Conjugative plasmid        MGE length: 153214 bp
Accession: NZ_CP082012        Location: 1..153214         Organism: Klebsiella pneumoniae strain KP18-41       Replicon: plasmid pKP18-41-KPC2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6147_RS27885 (1) 1..720 + 720 WP_040120350.1 replication initiation protein -
K6147_RS27890 (2229) 2229..7088 + 4860 WP_040120352.1 DEAD/DEAH box helicase family protein -
K6147_RS27895 (7945) 7945..8271 - 327 WP_228301548.1 Tn3 family transposase TnBth3 Transposase
K6147_RS27900 (8262) 8262..8966 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6147_RS27905 (9018) 9018..9479 + 462 Protein_4 Tn3 family transposase TnpR_Tn3 Transposase
K6147_RS27910 (9602) 9602..10582 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
K6147_RS27915 (10858) 10858..11739 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
K6147_RS27920 (11989) 11989..12870 - 882 Protein_7 IS1182 family transposase ISKpn6 Transposase
K6147_RS27925 (12974) 12974..13270 - 297 WP_013213987.1 transcriptional regulator -
K6147_RS27930 (13316) 13316..13471 - 156 WP_013213988.1 hypothetical protein -
K6147_RS27935 (13599) 13599..14024 - 426 WP_013213989.1 antirestriction protein -
K6147_RS27940 (14135) 14135..14413 - 279 WP_013213990.1 hypothetical protein -
K6147_RS27945 (14947) 14947..15564 - 618 Protein_12 replication protein -
K6147_RS27950 (15956) 15956..16516 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
K6147_RS27955 (16520) 16520..17593 + 1074 Protein_14 Tn3 family transposase TnpA_TnAs1 Transposase
K6147_RS27960 (17646) 17646..18350 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6147_RS27965 (18574) 18574..18687 - 114 WP_014343462.1 hypothetical protein -
K6147_RS27970 (19223) 19223..20089 + 867 WP_004118283.1 replication initiation protein -
K6147_RS27975 (21199) 21199..22404 + 1206 WP_011977818.1 AAA family ATPase -
K6147_RS27980 (22404) 22404..23378 + 975 WP_011977819.1 ParB family protein -
K6147_RS27985 (23460) 23460..24731 - 1272 WP_013214011.1 Y-family DNA polymerase -
K6147_RS27990 (24731) 24731..25162 - 432 WP_001568036.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
K6147_RS27995 (25569) 25569..27056 + 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
K6147_RS28000 (27305) 27305..28276 + 972 WP_004152353.1 plasmid segregation protein ParM -
K6147_RS28005 (28279) 28279..28950 + 672 WP_013214012.1 plasmid partitioning/stability family protein -
K6147_RS28010 (29013) 29013..29243 + 231 WP_001568040.1 hypothetical protein -
K6147_RS29070 (29439) 29439..29608 + 170 Protein_26 hypothetical protein -
K6147_RS28015 (29680) 29680..30381 + 702 WP_001568041.1 DNA methylase -
K6147_RS28020 (30381) 30381..30602 + 222 WP_001568042.1 hypothetical protein -
K6147_RS28025 (30612) 30612..31031 + 420 WP_001568043.1 DUF1380 domain-containing protein -
K6147_RS28030 (31085) 31085..31852 + 768 WP_013214013.1 hypothetical protein -
K6147_RS28035 (32533) 32533..32961 + 429 WP_001568045.1 antirestriction protein -
K6147_RS28040 (33004) 33004..33510 + 507 WP_013214014.1 antirestriction protein ArdA -
K6147_RS28045 (33553) 33553..33744 + 192 WP_001568047.1 hypothetical protein -
K6147_RS28050 (33932) 33932..34186 + 255 WP_011977779.1 DNA polymerase III subunit theta -
K6147_RS28055 (34221) 34221..34541 + 321 WP_001568049.1 hypothetical protein -
K6147_RS28060 (35221) 35221..35448 + 228 WP_001568050.1 hypothetical protein -
K6147_RS28065 (35540) 35540..35770 + 231 WP_001568051.1 hypothetical protein -
K6147_RS28070 (35822) 35822..37177 + 1356 WP_014343515.1 DUF3560 domain-containing protein -
K6147_RS28075 (37225) 37225..37788 + 564 WP_014343514.1 methyltransferase -
K6147_RS28080 (38621) 38621..39163 + 543 WP_014343512.1 single-stranded DNA-binding protein -
K6147_RS28085 (39212) 39212..39460 + 249 WP_001568055.1 DUF905 domain-containing protein -
K6147_RS28090 (39530) 39530..41587 + 2058 WP_015493064.1 ParB/RepB/Spo0J family partition protein -
K6147_RS28095 (41632) 41632..42063 + 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
K6147_RS28100 (42060) 42060..42788 + 729 WP_001568058.1 plasmid SOS inhibition protein A -
K6147_RS28105 (42785) 42785..43111 + 327 WP_013023807.1 hypothetical protein -
K6147_RS28110 (43167) 43167..43541 + 375 WP_014343510.1 hypothetical protein -
K6147_RS29075 (43711) 43711..43860 + 150 Protein_47 DUF5431 family protein -
K6147_RS28115 (43811) 43811..43927 + 117 WP_055313929.1 type I toxin-antitoxin system Hok family toxin -
K6147_RS28120 (44620) 44620..44892 + 273 WP_040245921.1 hypothetical protein -
K6147_RS28125 (44889) 44889..45239 + 351 WP_040245917.1 hypothetical protein -
K6147_RS28130 (45254) 45254..45571 + 318 WP_014343505.1 hypothetical protein -
K6147_RS28135 (46412) 46412..46768 + 357 WP_014343501.1 hypothetical protein -
K6147_RS28140 (46829) 46829..47041 + 213 WP_014343500.1 hypothetical protein -
K6147_RS28145 (47052) 47052..47276 + 225 WP_014343499.1 hypothetical protein -
K6147_RS28150 (47357) 47357..47677 + 321 WP_014343498.1 type II toxin-antitoxin system RelE/ParE family toxin -
K6147_RS28155 (47667) 47667..47945 + 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
K6147_RS29080 (47949) 47949..48053 + 105 Protein_57 transcriptional regulator -
K6147_RS28160 (48631) 48631..49335 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6147_RS28165 (49664) 49664..50614 + 951 WP_015493085.1 Recombination-promoting nuclease RpnA VF
K6147_RS28170 (50611) 50611..51222 - 612 WP_015493086.1 DUF2913 family protein -
K6147_RS28175 (51219) 51219..51614 - 396 WP_015493087.1 hypothetical protein -
K6147_RS28180 (51667) 51667..52059 - 393 Protein_62 3'-5' exonuclease -
K6147_RS28185 (52128) 52128..53108 + 981 WP_000019445.1 IS5 family transposase ISKpn26 Transposase
K6147_RS28190 (53090) 53090..53632 + 543 WP_077273850.1 restriction endonuclease -
K6147_RS28195 (53760) 53760..54317 + 558 WP_042934582.1 hypothetical protein -
K6147_RS28200 (54786) 54786..55490 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6147_RS28205 (55623) 55623..56264 - 642 WP_001011939.1 Chloramphenicol acetyltransferase 2 ARG
K6147_RS28210 (56414) 56414..56914 - 501 WP_001239317.1 hypothetical protein -
K6147_RS28215 (56994) 56994..57698 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6147_RS28220 (57704) 57704..57844 + 141 WP_001044210.1 hypothetical protein -
K6147_RS28225 (58330) 58330..59067 + 738 WP_001446887.1 Tn3 family transposase TnpR_TnEc1 Transposase
K6147_RS28230 (59064) 59064..59288 + 225 WP_000743213.1 hypothetical protein -
K6147_RS29085 (59410) 59410..59496 + 87 Protein_73 Arm DNA-binding domain-containing protein -
K6147_RS28240 (59768) 59768..60772 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
K6147_RS28245 (60851) 60851..63817 - 2967 WP_042863651.1 Tn3 family transposase TnpA_ISPa38 Transposase
K6147_RS28250 (63820) 63820..63885 - 66 Protein_76 helix-turn-helix domain-containing protein -
K6147_RS28255 (63938) 63938..64642 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6147_RS28260 (64667) 64667..64867 + 201 WP_072354025.1 hypothetical protein -
K6147_RS28265 (64887) 64887..65633 + 747 WP_000205770.1 conjugal transfer pilus acetylase TraX -
K6147_RS28270 (65688) 65688..66248 + 561 WP_000139328.1 fertility inhibition protein FinO -
K6147_RS28275 (66380) 66380..66580 + 201 WP_015059022.1 hypothetical protein -
K6147_RS28280 (66966) 66966..67565 + 600 WP_032083981.1 PIN domain-containing protein -
K6147_RS28285 (67627) 67627..67959 + 333 WP_152916585.1 hypothetical protein -
- (68160) 68160..68219 - 60 NuclAT_1 - Antitoxin Detail
- (68160) 68160..68219 - 60 NuclAT_1 - Antitoxin Detail
- (68160) 68160..68219 - 60 NuclAT_1 - Antitoxin Detail
- (68160) 68160..68219 - 60 NuclAT_1 - Antitoxin Detail
K6147_RS28290 (68264) 68264..68413 + 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
K6147_RS28295 (68697) 68697..68945 + 249 WP_000083837.1 replication regulatory protein RepA -
K6147_RS29090 (69060) 69060..69238 + 179 Protein_86 protein CopA/IncA -
K6147_RS28305 (69257) 69257..70114 + 858 WP_142295464.1 incFII family plasmid replication initiator RepA -
K6147_RS28310 (71053) 71053..71706 + 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
K6147_RS28315 (71799) 71799..72056 + 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
K6147_RS28320 (71989) 71989..72390 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
K6147_RS28325 (72639) 72639..73054 + 416 Protein_91 IS1-like element IS1B family transposase -
K6147_RS28330 (73090) 73090..73635 - 546 Protein_92 Tn3 family transposase TnpA_Tn3 Transposase
K6147_RS28335 (73701) 73701..74405 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6147_RS28340 (74475) 74475..74666 + 192 Protein_94 IS1380 family transposase -
K6147_RS28345 (74916) 74916..75791 + 876 WP_013188475.1 Beta-lactamase Toho-1 ARG
K6147_RS28350 (75826) 75826..76794 + 969 WP_013362812.1 IS5 family transposase IS903B Transposase
K6147_RS28355 (76851) 76851..77948 + 1098 Protein_97 TonB-dependent receptor -
K6147_RS28360 (78016) 78016..78492 - 477 Protein_98 PAS domain-containing protein -
K6147_RS28365 (78545) 78545..79249 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6147_RS28370 (79635) 79635..80051 + 417 WP_014839980.1 Glutathione transferase FosA ARG
K6147_RS28375 (80056) 80056..80574 - 519 WP_014839979.1 FidL-like protein -
K6147_RS28380 (80640) 80640..81344 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6147_RS28385 (81817) 81817..82521 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6147_RS28390 (82587) 82587..82790 - 204 Protein_104 IS6 family transposase IS15 Transposase
K6147_RS28395 (82790) 82790..83518 - 729 WP_001230787.1 type-F conjugative transfer system secretin TraK -
K6147_RS28400 (83505) 83505..84071 - 567 WP_000399794.1 type IV conjugative transfer system protein TraE -
K6147_RS28405 (84093) 84093..84404 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
K6147_RS28410 (84419) 84419..84784 - 366 WP_021519752.1 type IV conjugative transfer system pilin TraA -
K6147_RS28415 (84818) 84818..85045 - 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
K6147_RS28420 (85139) 85139..85825 - 687 WP_015059009.1 PAS domain-containing protein -
K6147_RS28425 (86016) 86016..86399 - 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
K6147_RS28430 (86676) 86676..87323 + 648 WP_015059008.1 hypothetical protein VF
K6147_RS28435 (87620) 87620..88441 - 822 WP_001234445.1 DUF932 domain-containing protein -
K6147_RS28440 (88552) 88552..88848 - 297 WP_001272251.1 hypothetical protein -
K6147_RS28445 (89148) 89148..89444 + 297 Protein_115 hypothetical protein -
K6147_RS28450 (89763) 89763..89888 - 126 WP_001372321.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
K6147_RS29100 (89830) 89830..89979 - 150 Protein_117 plasmid maintenance protein Mok -
- (89965) 89965..90189 - 225 NuclAT_0 - Antitoxin Detail
- (89965) 89965..90189 - 225 NuclAT_0 - Antitoxin Detail
- (89965) 89965..90189 - 225 NuclAT_0 - Antitoxin Detail
- (89965) 89965..90189 - 225 NuclAT_0 - Antitoxin Detail
K6147_RS28455 (90201) 90201..90920 - 720 WP_001276217.1 plasmid SOS inhibition protein A -
K6147_RS28460 (90917) 90917..91351 - 435 WP_000845953.1 conjugation system SOS inhibitor PsiB -
K6147_RS28465 (91420) 91420..93443 - 2024 Protein_120 ParB/RepB/Spo0J family partition protein -
K6147_RS28470 (93504) 93504..93737 - 234 WP_000006003.1 DUF905 family protein -
K6147_RS28475 (93795) 93795..94322 - 528 WP_000290834.1 single-stranded DNA-binding protein -
K6147_RS29105 (94624) 94624..95091 + 468 Protein_123 hypothetical protein -
K6147_RS28480 (95177) 95177..95740 - 564 WP_015059007.1 class I SAM-dependent methyltransferase -
K6147_RS28485 (95787) 95787..97148 - 1362 WP_000170695.1 DUF3560 domain-containing protein -
K6147_RS28490 (97200) 97200..97430 - 231 WP_000218642.1 hypothetical protein -
K6147_RS29110 (97947) 97947..98101 + 155 Protein_127 hypothetical protein -
K6147_RS28495 (98830) 98830..100497 + 1668 WP_012372796.1 group II intron reverse transcriptase/maturase -
K6147_RS28500 (100811) 100811..101002 - 192 WP_001027493.1 hypothetical protein -
K6147_RS28505 (100999) 100999..101421 - 423 WP_000271762.1 DUF1380 family protein -
K6147_RS28510 (101468) 101468..101893 - 426 WP_001198928.1 antirestriction protein -
K6147_RS28515 (102311) 102311..103087 - 777 WP_001383963.1 hypothetical protein -
K6147_RS28520 (103138) 103138..103572 - 435 WP_000274503.1 DUF1380 family protein -
K6147_RS28525 (103586) 103586..103807 - 222 WP_001104881.1 hypothetical protein -
K6147_RS28530 (103808) 103808..104491 - 684 WP_000085883.1 DNA methylase -
K6147_RS28535 (104568) 104568..104861 - 294 WP_032146011.1 hypothetical protein -
K6147_RS28540 (105008) 105008..105970 + 963 WP_000959884.1 plasmid segregation protein ParM -
K6147_RS28545 (105973) 105973..106323 + 351 WP_000361389.1 plasmid partitioning/stability family protein -
K6147_RS28550 (106446) 106446..106727 - 282 WP_001333089.1 hypothetical protein -
K6147_RS28555 (106855) 106855..107089 - 235 Protein_140 type II toxin-antitoxin system RelE/ParE family toxin -
K6147_RS28560 (108538) 108538..108603 - 66 Protein_141 IS1 family transposase -
K6147_RS28565 (108669) 108669..109373 + 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
K6147_RS28570 (109428) 109428..109742 + 315 Protein_143 hypothetical protein -
K6147_RS28575 (109823) 109823..110578 - 756 WP_012372818.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
K6147_RS28580 (110748) 110748..111608 - 861 WP_000027057.1 Beta-lactamase TEM ARG
K6147_RS28585 (111791) 111791..112327 - 537 WP_064441864.1 Tn3 family transposase TnpR_Tn3 Transposase
K6147_RS28590 (112419) 112419..112607 + 189 WP_000957857.1 hypothetical protein -
K6147_RS28595 (112617) 112617..113234 + 618 Protein_148 IS91 family transposase ISSbo1 Transposase
K6147_RS28600 (113285) 113285..113989 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6147_RS28605 (114054) 114054..114644 + 591 Protein_150 IS91 family transposase ISSbo1 Transposase
K6147_RS28610 (114751) 114751..115455 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6147_RS28615 (115346) 115346..115831 - 486 WP_228301550.1 Tn3 family transposase TnpR_ISPa38 Transposase
K6147_RS28620 (116071) 116071..117285 + 1215 WP_005012528.1 type II site-specific deoxyribonuclease -
K6147_RS28625 (117319) 117319..118752 - 1434 WP_001288432.1 DNA cytosine methyltransferase -
K6147_RS28630 (118851) 118851..119123 + 273 Protein_155 IS1 family transposase -
K6147_RS28635 (119134) 119134..119340 - 207 WP_001749967.1 hypothetical protein -
K6147_RS28640 (119345) 119345..119986 - 642 WP_012561158.1 restriction endonuclease -
K6147_RS28645 (120042) 120042..120353 - 312 WP_013279382.1 hypothetical protein -
K6147_RS28650 (120389) 120389..120703 - 315 WP_016338363.1 TrbM/KikA/MpfK family conjugal transfer protein -
K6147_RS28655 (120700) 120700..121044 - 345 WP_012561155.1 hypothetical protein -
K6147_RS28660 (121060) 121060..121365 - 306 WP_012561154.1 H-NS family nucleoid-associated regulatory protein -
K6147_RS28665 (121474) 121474..122211 + 738 WP_013279384.1 Type IV secretion system protein virB1 VF
K6147_RS28670 (122220) 122220..122501 + 282 WP_016338364.1 transcriptional repressor KorA -
K6147_RS28675 (122511) 122511..122804 + 294 WP_001749962.1 hypothetical protein -
K6147_RS28680 (122854) 122854..123171 + 318 WP_000496058.1 hypothetical protein VF
K6147_RS28685 (123171) 123171..125771 + 2601 WP_012561149.1 Type IV secretion system protein virB4 VF
K6147_RS28690 (125789) 125789..126502 + 714 WP_001749960.1 Type IV secretion system protein virB5 VF
K6147_RS28695 (126510) 126510..126737 + 228 WP_001749959.1 IncN-type entry exclusion lipoprotein EexN -
K6147_RS28700 (126753) 126753..127793 + 1041 WP_001749958.1 type IV secretion system protein -
K6147_RS28705 (128012) 128012..128710 + 699 WP_000646594.1 Type IV secretion system protein virB8 VF
K6147_RS28710 (128721) 128721..129605 + 885 WP_000735066.1 Type IV secretion system protein virB9 VF
K6147_RS28715 (129605) 129605..130765 + 1161 WP_012561145.1 Protein virB10 VF
K6147_RS28720 (130807) 130807..131802 + 996 WP_012561144.1 Type IV secretion system protein VirB11 VF
K6147_RS28725 (131802) 131802..132335 + 534 WP_000792636.1 Phospholipase D VF
K6147_RS28730 (132508) 132508..132822 - 315 WP_000091613.1 hypothetical protein -
K6147_RS28735 (133077) 133077..133433 - 357 WP_000215515.1 cupin domain-containing protein -
K6147_RS28740 (133423) 133423..133824 - 402 WP_001293886.1 DUF86 domain-containing protein -
K6147_RS28745 (133821) 133821..134111 - 291 WP_001247892.1 nucleotidyltransferase -
K6147_RS28750 (134175) 134175..134573 - 399 WP_012561143.1 hypothetical protein -
K6147_RS28755 (134573) 134573..137809 - 3237 WP_012561142.1 Multifunctional conjugation protein TraI Relaxase
K6147_RS28760 (137809) 137809..139338 - 1530 WP_000342688.1 type IV secretion system DNA-binding domain-containing protein -
K6147_RS28765 (139340) 139340..139756 - 417 WP_001749975.1 hypothetical protein -
K6147_RS28770 (140324) 140324..140710 + 387 WP_013279398.1 plasmid stabilization protein StbA -
K6147_RS28775 (140719) 140719..141435 + 717 WP_012561139.1 StbB family protein -
K6147_RS28780 (141437) 141437..141805 + 369 WP_012561138.1 plasmid stabilization protein StbC -
K6147_RS28785 (142006) 142006..142350 + 345 WP_012561137.1 hypothetical protein -
K6147_RS28790 (142812) 142812..142991 - 180 WP_012561134.1 protein CcgAI -
K6147_RS28795 (143822) 143822..144331 - 510 WP_012561131.1 antirestriction protein ArdA -
K6147_RS28800 (145682) 145682..146014 - 333 WP_040120360.1 hypothetical protein -
K6147_RS28805 (146223) 146223..146507 - 285 WP_013263793.1 protein CcgC -
K6147_RS29115 (146576) 146576..146776 - 201 WP_020319888.1 hypothetical protein -
K6147_RS28815 (146932) 146932..147228 - 297 WP_000545925.1 protein CcgD -
K6147_RS28820 (148112) 148112..148351 - 240 WP_032335150.1 hypothetical protein -
K6147_RS28825 (148361) 148361..148765 - 405 WP_000881513.1 antirestriction protein ArdAB regulator ArdR -
K6147_RS28830 (148823) 148823..149248 - 426 WP_000447669.1 antirestriction protein ArdB -
K6147_RS28835 (149664) 149664..150104 + 441 WP_000861760.1 translesion error-prone DNA polymerase V autoproteolytic subunit MucA -
K6147_RS28840 (150092) 150092..151357 + 1266 WP_012561122.1 translesion error-prone DNA polymerase V subunit MucB -
K6147_RS28845 (151508) 151508..152299 + 792 WP_012561121.1 SprT-like domain-containing protein -
K6147_RS28850 (152314) 152314..152655 - 342 WP_000057569.1 antirestriction protein ArdAB regulator ArdK -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance