NZ_CP0820071..174262

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 174262 bp
Accession: NZ_CP082007        Location: 1..174262         Organism: Klebsiella pneumoniae strain KP18-8       Replicon: plasmid pKP18-8-1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K6148_RS27400 (667) 667..1080 - 414 WP_069985713.1 helix-turn-helix domain-containing protein -
K6148_RS27405 (1081) 1081..1359 - 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
K6148_RS27410 (1349) 1349..1669 - 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
K6148_RS27415 (1750) 1750..1974 - 225 WP_014343499.1 hypothetical protein -
K6148_RS27420 (1985) 1985..2197 - 213 WP_019706020.1 hypothetical protein -
K6148_RS27425 (2258) 2258..2614 - 357 WP_019706019.1 hypothetical protein -
K6148_RS27430 (3246) 3246..3596 - 351 WP_023287104.1 hypothetical protein -
K6148_RS27435 (3593) 3593..3865 - 273 WP_023287105.1 hypothetical protein -
K6148_RS27440 (4558) 4558..4656 - 99 WP_159224797.1 Hok/Gef family protein -
K6148_RS28620 (4631) 4631..4687 - 57 Protein_9 modulator protein -
K6148_RS27445 (4786) 4786..5859 + 1074 WP_048270288.1 IS481 family transposase ISKpn28 Transposase
- (5859) 5859..5983 - 125 NuclAT_0 - -
- (5859) 5859..5983 - 125 NuclAT_0 - -
- (5859) 5859..5983 - 125 NuclAT_0 - -
- (5859) 5859..5983 - 125 NuclAT_0 - -
K6148_RS27450 (6043) 6043..6417 - 375 WP_023287106.1 hypothetical protein -
K6148_RS27455 (6473) 6473..6799 - 327 WP_001568059.1 hypothetical protein -
K6148_RS27460 (6796) 6796..7524 - 729 WP_040194708.1 plasmid SOS inhibition protein A -
K6148_RS27465 (7521) 7521..7952 - 432 WP_001568057.1 conjugation system SOS inhibitor PsiB -
K6148_RS27470 (7997) 7997..10054 - 2058 WP_069335038.1 ParB/RepB/Spo0J family partition protein -
K6148_RS27475 (10124) 10124..10372 - 249 WP_009310026.1 DUF905 domain-containing protein -
K6148_RS27480 (10421) 10421..10963 - 543 WP_015065513.1 single-stranded DNA-binding protein -
K6148_RS27485 (11794) 11794..12357 - 564 WP_004152756.1 methyltransferase -
K6148_RS27490 (12405) 12405..13760 - 1356 WP_032418010.1 DUF3560 domain-containing protein -
K6148_RS27495 (13812) 13812..14042 - 231 WP_001568051.1 hypothetical protein -
K6148_RS27500 (14134) 14134..14361 - 228 WP_004178072.1 hypothetical protein -
K6148_RS27505 (15142) 15142..15459 - 318 WP_004118473.1 hypothetical protein -
K6148_RS27510 (15494) 15494..15748 - 255 WP_004152754.1 DNA polymerase III subunit theta -
K6148_RS27515 (15985) 15985..16410 - 426 WP_004118478.1 antirestriction protein -
K6148_RS27520 (16931) 16931..17161 - 231 WP_004118481.1 hypothetical protein -
K6148_RS27525 (17396) 17396..18883 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
K6148_RS27530 (19285) 19285..19710 + 426 WP_004182047.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
K6148_RS27535 (19710) 19710..20981 + 1272 WP_014386156.1 Y-family DNA polymerase -
K6148_RS27540 (21120) 21120..21275 + 156 WP_001776126.1 hypothetical protein -
K6148_RS27545 (21298) 21298..22496 - 1199 Protein_30 IS200-IS605 family transposase IS609 Transposase
K6148_RS27550 (23805) 23805..24776 - 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
K6148_RS27555 (24776) 24776..25942 - 1167 WP_000523813.1 Sporulation initiation inhibitor protein Soj VF
K6148_RS27560 (26694) 26694..27704 + 1011 WP_000200070.1 RepB family plasmid replication initiator protein -
K6148_RS27565 (28421) 28421..29161 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
K6148_RS27570 (30305) 30305..31252 + 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
K6148_RS27575 (31279) 31279..31521 - 243 WP_074428705.1 EAL domain-containing protein -
K6148_RS27580 (31610) 31610..32579 + 970 Protein_37 IS5 family transposase IS903B Transposase
K6148_RS27585 (33252) 33252..33509 - 258 WP_004197688.1 hypothetical protein -
K6148_RS28550 (34150) 34150..34665 + 516 Protein_39 putative cyclic di-GMP phosphodiesterase PdeB VF
K6148_RS28555 (34729) 34729..35565 + 837 WP_004178087.1 putative cyclic di-GMP phosphodiesterase PdeB VF
K6148_RS27600 (37325) 37325..38602 - 1278 WP_004152070.1 DUF2254 domain-containing protein -
K6148_RS27605 (38665) 38665..40662 - 1998 WP_004178088.1 choline BCCT transporter BetT -
K6148_RS27620 (43000) 43000..43484 + 485 Protein_46 IS1 family transposase IS1X2 Transposase
K6148_RS27625 (43500) 43500..44042 + 543 Protein_47 ISL3 family transposase ISKpn25 Transposase
K6148_RS27630 (44338) 44338..44769 - 432 WP_004178091.1 silver-binding protein SilE -
K6148_RS27635 (45020) 45020..46495 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
K6148_RS27640 (46488) 46488..47168 - 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
K6148_RS27645 (47358) 47358..48743 + 1386 WP_000475512.1 Cation efflux system protein CusC VF
K6148_RS27650 (48772) 48772..49125 + 354 WP_001246153.1 cation efflux system protein CusF -
K6148_RS27655 (49239) 49239..50531 + 1293 WP_004152079.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
K6148_RS27660 (50542) 50542..53688 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
K6148_RS27665 (53775) 53775..54215 + 441 WP_000758228.1 DUF411 domain-containing protein -
K6148_RS27670 (54342) 54342..56789 + 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
K6148_RS27675 (56830) 56830..57027 + 198 WP_000843497.1 DUF2933 domain-containing protein -
K6148_RS27680 (57061) 57061..57798 - 738 WP_004118669.1 Murein DD-endopeptidase MepM VF
K6148_RS27685 (58087) 58087..58536 - 450 WP_001023257.1 copper resistance protein -
K6148_RS27690 (58770) 58770..60587 + 1818 WP_000925242.1 multicopper oxidase PcoA -
K6148_RS27695 (60593) 60593..61483 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
K6148_RS27700 (61523) 61523..61903 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
K6148_RS27705 (61908) 61908..62837 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
K6148_RS27710 (62892) 62892..63572 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
K6148_RS27715 (63569) 63569..64969 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
K6148_RS27720 (65186) 65186..65620 + 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
K6148_RS27725 (65852) 65852..66031 - 180 WP_004152086.1 type II toxin-antitoxin system RelE/ParE family toxin -
K6148_RS27730 (66092) 66092..67712 - 1621 Protein_68 ISL3 family transposase ISEc38 Transposase
K6148_RS27735 (67828) 67828..68283 + 456 WP_004152090.1 aquaporin -
K6148_RS27740 (68333) 68333..68830 - 498 WP_004152091.1 GNAT family N-acetyltransferase -
K6148_RS27745 (69162) 69162..69488 + 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
K6148_RS27750 (69485) 69485..70198 + 714 WP_004152093.1 arsenical resistance protein ArsH -
K6148_RS27755 (70207) 70207..70752 + 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
K6148_RS27760 (70828) 70828..71190 + 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
K6148_RS27765 (71215) 71215..72965 + 1751 Protein_75 arsenical pump-driving ATPase -
K6148_RS27770 (73087) 73087..73623 + 537 WP_004152096.1 GNAT family N-acetyltransferase -
K6148_RS27775 (73656) 73656..74081 - 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
K6148_RS27780 (74094) 74094..75383 - 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
K6148_RS27785 (75431) 75431..77182 - 1752 WP_004152099.1 Arsenical pump-driving ATPase VF
K6148_RS27790 (77200) 77200..77562 - 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
K6148_RS27795 (77612) 77612..77962 - 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
K6148_RS27800 (78320) 78320..78589 + 270 WP_004152102.1 hypothetical protein -
K6148_RS27805 (78577) 78577..79152 + 576 WP_004152103.1 hypothetical protein -
K6148_RS27810 (79183) 79183..79677 + 495 WP_004152104.1 DNA-binding protein -
K6148_RS27815 (79721) 79721..80089 + 369 WP_004152105.1 hypothetical protein -
K6148_RS27820 (80123) 80123..80326 + 204 WP_004152106.1 HHA domain-containing protein -
K6148_RS27825 (80375) 80375..80632 + 258 WP_004152107.1 hypothetical protein -
K6148_RS27830 (80708) 80708..80962 + 255 WP_004152108.1 hypothetical protein -
K6148_RS27835 (81138) 81138..81404 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
K6148_RS27840 (81392) 81392..81874 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
K6148_RS27845 (82075) 82075..83478 + 1404 WP_001567368.1 ISNCY family transposase ISKpn21 Transposase
K6148_RS27850 (83507) 83507..84139 - 633 WP_001567369.1 hypothetical protein -
K6148_RS27855 (84369) 84369..85715 + 1347 WP_020314316.1 ISNCY family transposase ISLad2 Transposase
K6148_RS28625 (85876) 85876..86007 + 132 WP_004218042.1 hypothetical protein -
K6148_RS27860 (86216) 86216..87381 - 1166 Protein_95 IS3 family transposase ISKpn38 Transposase
K6148_RS27865 (87558) 87558..88520 - 963 WP_004152113.1 zinc metalloprotease HtpX -
K6148_RS27870 (88507) 88507..88995 - 489 WP_004152114.1 phosphate-starvation-inducible PsiE family protein -
K6148_RS28560 (89110) 89110..89256 - 147 Protein_98 diguanylate cyclase -
K6148_RS27875 (89494) 89494..89691 - 198 WP_004152115.1 hypothetical protein -
K6148_RS27880 (89691) 89691..92486 - 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
K6148_RS27885 (92601) 92601..93170 - 570 WP_004152117.1 Spore protein SP21 VF
K6148_RS27890 (93205) 93205..93486 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
K6148_RS27895 (93730) 93730..93993 - 264 WP_004118208.1 hypothetical protein -
K6148_RS27900 (94008) 94008..94271 + 264 WP_004118209.1 transposase -
K6148_RS27905 (94216) 94216..94332 + 117 Protein_105 transposase domain-containing protein -
K6148_RS27910 (94517) 94517..95214 + 698 WP_228199704.1 IS1 family transposase IS1X2 Transposase
K6148_RS27915 (95473) 95473..96453 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
K6148_RS27920 (97035) 97035..97554 - 520 Protein_108 IS5 family transposase ISPst7 Transposase
K6148_RS27925 (97662) 97662..98531 - 870 WP_004152692.1 HTH-type transcriptional activator CmpR VF
K6148_RS27930 (98525) 98525..99535 - 1011 WP_004152693.1 phosphonate dehydrogenase PtxD -
K6148_RS27935 (99544) 99544..100371 - 828 WP_004152694.1 phosphonate ABC transporter, permease protein PhnE -
K6148_RS27940 (100380) 100380..101243 - 864 WP_004152695.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
K6148_RS27945 (101240) 101240..102067 - 828 WP_014386147.1 Glutamine transport ATP-binding protein GlnQ VF
K6148_RS27950 (102409) 102409..102717 + 309 Protein_114 IS5 family transposase ISThi1 Transposase
K6148_RS27955 (102923) 102923..103627 - 705 WP_004217321.1 IS6 family transposase IS26 Transposase
K6148_RS27960 (103711) 103711..104883 + 1173 Protein_116 Tn3 family transposase TnpA_ISSba14 Transposase
K6148_RS27965 (104962) 104962..105966 + 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
K6148_RS27970 (106258) 106258..106926 + 669 WP_044117068.1 IS6 family transposase IS26 Transposase
K6148_RS27975 (107116) 107116..107931 - 816 WP_000018329.1 Aminoglycoside 3'-phosphotransferase ARG
K6148_RS27980 (108082) 108082..108786 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6148_RS27985 (108792) 108792..109340 + 549 WP_050497034.1 Tn3 family transposase TnpR_Tn5403 Transposase
K6148_RS27990 (109364) 109364..111328 - 1965 Protein_122 Tn3 family transposase TnpA_TnAs1 Transposase
K6148_RS27995 (111332) 111332..111892 - 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
K6148_RS28000 (112068) 112068..112418 - 351 WP_000454193.1 DUF3330 domain-containing protein -
K6148_RS28005 (112621) 112621..112842 - 222 Protein_125 tyrosine-type recombinase/integrase -
K6148_RS28010 (112897) 112897..113601 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
K6148_RS28015 (113663) 113663..113776 - 114 Protein_127 recombinase family protein -
K6148_RS28020 (113871) 113871..116768 + 2898 WP_001553819.1 Tn3 family transposase TnpA_Tn5403 Transposase
K6148_RS28025 (116905) 116905..117306 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
K6148_RS28030 (117239) 117239..117496 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
K6148_RS28035 (117589) 117589..118242 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
K6148_RS28040 (119231) 119231..120088 - 858 WP_004099067.1 incFII family plasmid replication initiator RepA -
K6148_RS28050 (120374) 120374..120652 - 279 WP_004099069.1 replication regulatory protein RepA -
K6148_RS28055 (120972) 120972..121523 - 552 WP_013213996.1 Phospholipase D VF
K6148_RS28565 (121628) 121628..121707 - 80 Protein_135 hypothetical protein -
K6148_RS28065 (122756) 122756..124798 - 2043 WP_014386214.1 DUF262 domain-containing protein -
K6148_RS28070 (124791) 124791..126242 - 1452 WP_000443938.1 DUF262 domain-containing protein -
K6148_RS28075 (126267) 126267..126575 - 309 Protein_139 IS3 family transposase ISLad1 Transposase
K6148_RS28080 (126592) 126592..126831 - 240 Protein_140 IS110 family transposase -
K6148_RS28085 (126830) 126830..127015 - 186 Protein_141 IS1-like element transposase -
K6148_RS28090 (127102) 127102..127857 - 756 WP_009310009.1 SprT family zinc-dependent metalloprotease -
K6148_RS28095 (127854) 127854..131138 - 3285 WP_032408860.1 type I restriction endonuclease subunit R -
K6148_RS28100 (131208) 131208..133070 - 1863 WP_014386212.1 cold shock domain-containing protein -
K6148_RS28105 (133015) 133015..133698 - 684 WP_014386211.1 YecA family protein -
K6148_RS28110 (133695) 133695..134921 - 1227 WP_014386210.1 restriction endonuclease subunit S -
K6148_RS28115 (134911) 134911..136434 - 1524 WP_014386209.1 type I restriction-modification system subunit M -
K6148_RS28120 (136738) 136738..137435 - 698 Protein_148 IS1 family transposase -
K6148_RS28125 (137621) 137621..138214 - 594 WP_004152380.1 fertility inhibition protein FinO -
K6148_RS28130 (138286) 138286..139011 - 726 WP_014386207.1 type-F conjugative transfer system pilin acetylase TraX -
K6148_RS28135 (139056) 139056..144314 - 5259 WP_222681358.1 Multifunctional conjugation protein TraI Relaxase
K6148_RS28140 (144314) 144314..146623 - 2310 WP_014386205.1 type IV conjugative transfer system coupling protein TraD -
K6148_RS28145 (146750) 146750..147439 - 690 WP_014343485.1 hypothetical protein -
K6148_RS28150 (147632) 147632..148363 - 732 WP_016831056.1 conjugal transfer complement resistance protein TraT -
K6148_RS28155 (148614) 148614..149216 - 603 WP_013214035.1 conjugal transfer protein TraS -
K6148_RS28160 (149239) 149239..152061 - 2823 WP_013214034.1 conjugal transfer mating-pair stabilization protein TraG -
K6148_RS28165 (152061) 152061..153440 - 1380 WP_014343487.1 conjugal transfer pilus assembly protein TraH -
K6148_RS28170 (153418) 153418..153861 - 444 WP_004194305.1 F-type conjugal transfer protein TrbF -
K6148_RS28175 (153907) 153907..154464 - 558 WP_013214031.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
K6148_RS28180 (154436) 154436..154675 - 240 WP_004144400.1 type-F conjugative transfer system pilin chaperone TraQ -
K6148_RS28185 (154686) 154686..155438 - 753 WP_004152677.1 type-F conjugative transfer system pilin assembly protein TraF -
K6148_RS28190 (155459) 155459..155785 - 327 WP_004152676.1 hypothetical protein -
K6148_RS28195 (155798) 155798..156046 - 249 WP_004152675.1 hypothetical protein -
K6148_RS28200 (156024) 156024..156278 - 255 WP_004152674.1 conjugal transfer protein TrbE -
K6148_RS28205 (156310) 156310..158265 - 1956 WP_030003482.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
K6148_RS28210 (158324) 158324..158962 - 639 WP_069985712.1 type-F conjugative transfer system pilin assembly protein TrbC -
K6148_RS28215 (158975) 158975..159964 - 990 WP_029497420.1 conjugal transfer pilus assembly protein TraU -
K6148_RS28220 (159961) 159961..160362 - 402 WP_004194979.1 hypothetical protein -
K6148_RS28225 (160397) 160397..161032 - 636 WP_029497419.1 type-F conjugative transfer system protein TraW -
K6148_RS28230 (161032) 161032..161421 - 390 WP_004167468.1 type-F conjugative transfer system protein TrbI -
K6148_RS28235 (161421) 161421..164060 - 2640 WP_013214024.1 type IV secretion system protein TraC -
K6148_RS28240 (164132) 164132..164530 - 399 WP_023179972.1 hypothetical protein -
K6148_RS28245 (164909) 164909..165313 - 405 WP_004197817.1 hypothetical protein -
K6148_RS28250 (165380) 165380..165691 - 312 WP_094965623.1 hypothetical protein -
K6148_RS28255 (165692) 165692..165910 - 219 WP_004195468.1 hypothetical protein -
K6148_RS28260 (166233) 166233..166817 - 585 WP_032440547.1 type IV conjugative transfer system lipoprotein TraV -
K6148_RS28265 (166890) 166890..168314 - 1425 WP_004194260.1 F-type conjugal transfer pilus assembly protein TraB -
K6148_RS28270 (168314) 168314..169054 - 741 WP_013023821.1 type-F conjugative transfer system secretin TraK -
K6148_RS28275 (169041) 169041..169607 - 567 WP_004144423.1 type IV conjugative transfer system protein TraE -
K6148_RS28280 (169627) 169627..169932 - 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
K6148_RS28285 (169946) 169946..170314 - 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
K6148_RS28295 (170669) 170669..171370 - 702 WP_004194113.1 hypothetical protein -
K6148_RS28300 (171600) 171600..171992 - 393 WP_004194114.1 conjugal transfer relaxosome DNA-binding protein TraM -
K6148_RS28305 (172424) 172424..172909 + 486 WP_032440470.1 hypothetical protein VF
K6148_RS28310 (172942) 172942..173271 - 330 WP_071994324.1 DUF5983 family protein -
K6148_RS28315 (173304) 173304..174125 - 822 WP_023287138.1 DUF932 domain-containing protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance