NZ_CP0765531..162180

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 162180 bp
Accession: NZ_CP076553        Location: 1..162180         Organism: Klebsiella pneumoniae strain 19PDR22       Replicon: plasmid p19PDR22-KPC3


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HF574_RS28485 (HF574_29220) 1..1101 + 1101 WP_000350011.1 RepB family plasmid replication initiator protein -
HF574_RS28490 (HF574_29225) 2138..2572 - 435 WP_000883925.1 hypothetical protein -
HF574_RS28495 (HF574_29230) 2590..3705 - 1116 WP_000946102.1 phosphoadenosine phosphosulfate reductase family protein -
HF574_RS28500 (HF574_29235) 3974..4582 + 609 WP_000849071.1 hypothetical protein -
HF574_RS28505 (HF574_29240) 4587..5108 + 522 WP_000393785.1 hypothetical protein -
HF574_RS28510 (HF574_29245) 5111..5632 + 522 WP_000805800.1 hypothetical protein -
HF574_RS28515 (HF574_29250) 5729..6202 + 474 WP_000057877.1 hypothetical protein -
HF574_RS28520 (HF574_29255) 6213..6506 + 294 WP_001370730.1 hypothetical protein -
HF574_RS28525 (HF574_29260) 6511..7365 + 855 WP_000539392.1 hypothetical protein -
HF574_RS28530 (HF574_29265) 7365..8324 + 960 WP_000829616.1 S49 family peptidase -
HF574_RS28535 (HF574_29270) 8340..9200 + 861 WP_000139698.1 DsbA family protein -
HF574_RS28540 (HF574_29275) 9234..9662 + 429 WP_000591074.1 hypothetical protein -
HF574_RS28545 (HF574_29280) 9719..10078 + 360 WP_000422768.1 hypothetical protein -
HF574_RS28550 (HF574_29285) 10078..10524 + 447 WP_000919345.1 Fe3+-siderophore ABC transporter permease -
HF574_RS28555 (HF574_29290) 10521..11039 + 519 WP_000210756.1 nitrite reductase -
HF574_RS28560 (HF574_29295) 11039..11269 + 231 WP_000972663.1 hypothetical protein -
HF574_RS28565 (HF574_29300) 11256..12094 + 839 Protein_17 hypothetical protein -
HF574_RS28570 (HF574_29305) 12325..12852 + 528 WP_001236377.1 thermonuclease family protein -
HF574_RS28575 (HF574_29310) 12910..13182 + 273 WP_001043047.1 HU family DNA-binding protein -
HF574_RS28580 (HF574_29315) 13270..13563 + 294 WP_001239997.1 chromosome segregation protein ParM -
HF574_RS28585 (HF574_29320) 13590..13892 - 303 WP_000124640.1 XRE family transcriptional regulator Antitoxin Detail
HF574_RS28590 (HF574_29325) 13897..14247 - 351 WP_000270043.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
HF574_RS28595 (HF574_29330) 14410..14958 + 549 WP_001061574.1 transcriptional regulator -
HF574_RS28600 (HF574_29335) 15299..15493 + 195 WP_000343597.1 hypothetical protein -
HF574_RS28605 (HF574_29340) 15504..15875 + 372 WP_000516916.1 hypothetical protein -
HF574_RS28610 (HF574_29345) 15868..16338 + 471 WP_001281821.1 hypothetical protein -
HF574_RS28615 (HF574_29350) 16353..16688 - 336 WP_000683476.1 hypothetical protein -
HF574_RS28620 (HF574_29355) 16785..17273 + 489 WP_001273096.1 DUF1643 domain-containing protein -
HF574_RS28625 (HF574_29360) 17276..17773 + 498 WP_000062185.1 hypothetical protein -
HF574_RS28630 (HF574_29365) 18335..19267 + 933 WP_000434071.1 hypothetical protein -
HF574_RS28635 (HF574_29370) 19341..20804 + 1464 WP_001280522.1 AAA family ATPase -
HF574_RS28640 (HF574_29375) 20960..21289 + 330 WP_000277953.1 hypothetical protein -
HF574_RS28645 (HF574_29380) 21294..21686 + 393 WP_000018404.1 hypothetical protein -
HF574_RS28650 (HF574_29385) 21735..21929 + 195 WP_000757530.1 DUF2997 domain-containing protein -
HF574_RS28655 (HF574_29390) 21974..23107 + 1134 WP_000225028.1 hypothetical protein -
HF574_RS28660 (HF574_29395) 23119..23466 + 348 WP_000039129.1 hypothetical protein -
HF574_RS28665 (HF574_29400) 23463..23891 + 429 WP_000988987.1 hypothetical protein -
HF574_RS28670 (HF574_29405) 23884..24447 + 564 WP_000004673.1 hypothetical protein -
HF574_RS28675 (HF574_29410) 24459..24947 + 489 WP_001256127.1 hypothetical protein -
HF574_RS28680 (HF574_29415) 24886..25203 + 318 WP_011742556.1 Type IV secretion system protein virB8 VF
HF574_RS28685 (HF574_29420) 25214..26098 + 885 WP_000735066.1 Type IV secretion system protein virB9 VF
HF574_RS28690 (HF574_29425) 26098..27258 + 1161 WP_000101710.1 Protein virB10 VF
HF574_RS28695 (HF574_29430) 27300..28295 + 996 WP_000128596.1 Type IV secretion system protein VirB11 VF
HF574_RS28700 (HF574_29435) 28295..28828 + 534 WP_000792636.1 Phospholipase D VF
HF574_RS28705 (HF574_29440) 29002..29130 - 129 WP_002210551.1 hypothetical protein -
HF574_RS28710 (HF574_29445) 29556..29735 + 180 Protein_46 helix-turn-helix domain-containing protein -
HF574_RS28715 (HF574_29450) 29800..30504 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HF574_RS28720 (HF574_29455) 30564..31577 - 1014 WP_000845048.1 IS91 family transposase ISAzo26 Transposase
HF574_RS28725 (HF574_29460) 31735..32208 + 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
HF574_RS28730 (HF574_29465) 32339..33127 + 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
HF574_RS28735 (HF574_29470) 33333..33680 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
HF574_RS28740 (HF574_29475) 33674..34513 + 840 WP_000259031.1 Dihydropteroate synthase ARG
HF574_RS28745 (HF574_29480) 34918..36459 + 1542 WP_000050481.1 IS91 family transposase ISVsa3 Transposase
HF574_RS28750 (HF574_29485) 36693..37532 + 840 Protein_54 IS5 family transposase ISEc35 Transposase
HF574_RS28755 (HF574_29490) 37858..38631 + 774 WP_000359986.1 16S rRNA (guanine(1405)-N(7))-methyltransferase ARG
HF574_RS28765 (HF574_29500) 39113..39298 - 186 WP_002026779.1 hypothetical protein -
HF574_RS28770 (HF574_29505) 39347..40531 + 1185 WP_002001451.1 IS4 family transposase ISEc29 Transposase
HF574_RS28775 (HF574_29510) 40930..42405 + 1476 WP_000052512.1 putative ABC transporter ATP-binding protein YbiT ARG
HF574_RS28780 (HF574_29515) 42461..43345 + 885 WP_000155092.1 hypothetical protein ARG
HF574_RS28785 (HF574_29520) 43704..44246 - 543 WP_004896925.1 plasmid replication DNA-binding protein -
HF574_RS28790 (HF574_29525) 44313..45065 - 753 Protein_61 replication initiation protein RepM -
HF574_RS28795 (HF574_29530) 45131..45835 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HF574_RS30515 45888..46184 - 297 Protein_63 Tn3 family transposase TnpR_ISThsp9 Transposase
HF574_RS28800 (HF574_29535) 46474..47496 - 1023 WP_000156884.1 IS110 family transposase IS5708 Transposase
HF574_RS28805 (HF574_29540) 47654..48490 - 837 WP_000480968.1 hypothetical protein ARG
HF574_RS28810 (HF574_29545) 48490..49293 - 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
HF574_RS28815 (HF574_29550) 49354..50169 - 816 WP_001043260.1 Dihydropteroate synthase ARG
HF574_RS28820 (HF574_29555) 50476..50787 + 312 WP_000338945.1 hypothetical protein -
HF574_RS28825 (HF574_29560) 50961..51746 + 786 WP_001151304.1 Sporulation initiation inhibitor protein Soj VF
HF574_RS28830 (HF574_29565) 51750..52931 + 1182 WP_001207227.1 KorB domain-containing protein -
HF574_RS28835 (HF574_29570) 52980..53252 + 273 WP_000703827.1 helix-turn-helix domain-containing protein -
HF574_RS28840 (HF574_29575) 53305..53940 - 636 WP_000074431.1 N-6 DNA methylase -
HF574_RS28845 (HF574_29580) 54032..54175 - 144 WP_000939033.1 hypothetical protein -
HF574_RS28850 (HF574_29585) 54494..54871 + 378 WP_001125905.1 hypothetical protein -
HF574_RS28855 (HF574_29590) 54864..55145 + 282 WP_000044824.1 hypothetical protein -
HF574_RS28860 (HF574_29595) 55120..55794 + 675 WP_000344151.1 thymidylate kinase -
HF574_RS28865 (HF574_29600) 55787..56293 + 507 WP_000566600.1 hypothetical protein -
HF574_RS28870 (HF574_29605) 56299..56610 + 312 WP_002210541.1 hypothetical protein -
HF574_RS28875 (HF574_29610) 56619..57119 + 501 WP_000647189.1 hypothetical protein -
HF574_RS28880 (HF574_29615) 57123..58550 + 1428 WP_000936896.1 DNA cytosine methyltransferase -
HF574_RS28885 (HF574_29620) 58550..59206 + 657 WP_000268551.1 hypothetical protein -
HF574_RS28890 (HF574_29625) 59412..59630 + 219 WP_000362482.1 hypothetical protein -
HF574_RS28895 (HF574_29630) 59724..60341 + 618 WP_000464631.1 hypothetical protein -
HF574_RS28900 (HF574_29635) 60618..61562 - 945 WP_216833411.1 IS30 family transposase ISAs2 Transposase
HF574_RS30520 61660..61935 + 276 WP_228745777.1 ASCH domain-containing protein -
HF574_RS28905 (HF574_29640) 62027..62515 - 489 WP_000468105.1 hypothetical protein -
HF574_RS28910 (HF574_29645) 62530..64722 - 2193 WP_000366822.1 DNA topoisomerase 3 -
HF574_RS28915 (HF574_29650) 64722..64955 - 234 WP_001191892.1 hypothetical protein -
HF574_RS28920 (HF574_29655) 64937..65554 - 618 WP_001249396.1 hypothetical protein -
HF574_RS28925 (HF574_29660) 65722..68700 + 2979 WP_001337757.1 hypothetical protein Relaxase
HF574_RS28930 (HF574_29665) 68697..70562 + 1866 WP_000178856.1 conjugative transfer system coupling protein TraD -
HF574_RS28935 (HF574_29670) 70612..71157 + 546 WP_000228720.1 hypothetical protein -
HF574_RS28940 (HF574_29675) 71114..71743 + 630 WP_000743450.1 DUF4400 domain-containing protein -
HF574_RS28945 (HF574_29680) 71753..72199 + 447 WP_000122506.1 hypothetical protein -
HF574_RS28950 (HF574_29685) 72209..72586 + 378 WP_000869261.1 hypothetical protein -
HF574_RS28955 (HF574_29690) 72586..73248 + 663 WP_001231463.1 hypothetical protein -
HF574_RS28960 (HF574_29695) 73429..73572 + 144 WP_001275801.1 hypothetical protein -
HF574_RS28965 (HF574_29700) 73584..73949 + 366 WP_001052531.1 hypothetical protein -
HF574_RS28970 (HF574_29705) 74094..74375 + 282 WP_000805625.1 type IV conjugative transfer system protein TraL -
HF574_RS28975 (HF574_29710) 74372..74998 + 627 WP_001049716.1 TraE/TraK family type IV conjugative transfer system protein -
HF574_RS28980 (HF574_29715) 74982..75899 + 918 WP_000794249.1 type-F conjugative transfer system secretin TraK -
HF574_RS28985 (HF574_29720) 75899..77212 + 1314 WP_024131605.1 TraB/VirB10 family protein -
HF574_RS28990 (HF574_29725) 77209..77787 + 579 WP_000793435.1 type IV conjugative transfer system lipoprotein TraV -
HF574_RS28995 (HF574_29730) 77791..78183 + 393 WP_000479535.1 TraA family conjugative transfer protein -
HF574_RS29000 (HF574_29735) 78384..83915 + 5532 WP_000606833.1 Ig-like domain-containing protein -
HF574_RS29005 (HF574_29740) 84064..84771 + 708 WP_001259347.1 DsbC family protein -
HF574_RS29010 (HF574_29745) 84768..87215 + 2448 WP_000637386.1 type IV secretion system protein TraC -
HF574_RS29015 (HF574_29750) 87230..87547 + 318 WP_000351984.1 hypothetical protein -
HF574_RS29020 (HF574_29755) 87544..88074 + 531 WP_001010738.1 S26 family signal peptidase -
HF574_RS29025 (HF574_29760) 88037..89302 + 1266 WP_000621288.1 TrbC family F-type conjugative pilus assembly protein -
HF574_RS29030 (HF574_29765) 89299..89970 + 672 WP_001337754.1 EAL domain-containing protein -
HF574_RS29035 (HF574_29770) 89970..90974 + 1005 WP_043940352.1 TraU family protein -
HF574_RS29040 (HF574_29775) 91090..93888 + 2799 WP_001256487.1 conjugal transfer mating pair stabilization protein TraN -
HF574_RS29045 (HF574_29780) 93927..94787 - 861 WP_000709517.1 hypothetical protein -
HF574_RS29050 (HF574_29785) 94910..95551 - 642 WP_000796664.1 hypothetical protein -
HF574_RS29055 (HF574_29790) 95845..96165 + 321 WP_000547566.1 hypothetical protein -
HF574_RS29060 (HF574_29795) 96469..96654 + 186 WP_001186917.1 hypothetical protein -
HF574_RS29065 (HF574_29800) 96874..97842 + 969 WP_000085162.1 CbbQ/NirQ/NorQ C-terminal domain-containing protein -
HF574_RS29070 (HF574_29805) 97853..98761 + 909 WP_000739139.1 hypothetical protein -
HF574_RS29075 (HF574_29810) 98822..99352 + 531 WP_000987165.1 single-stranded DNA-binding protein -
HF574_RS29080 (HF574_29815) 99447..100436 + 990 WP_001282585.1 phage recombination protein Bet -
HF574_RS29085 (HF574_29820) 100499..101509 + 1011 WP_000706865.1 YqaJ viral recombinase family protein -
HF574_RS29090 (HF574_29825) 101709..102986 + 1278 WP_000170086.1 DUF3150 domain-containing protein -
HF574_RS29095 (HF574_29830) 103071..104867 + 1797 WP_000039318.1 VWA domain-containing protein -
HF574_RS29100 (HF574_29835) 104929..105264 + 336 WP_001071288.1 hypothetical protein -
HF574_RS29105 (HF574_29840) 105529..106068 + 540 WP_000018872.1 hypothetical protein -
HF574_RS29110 (HF574_29845) 106159..106659 + 501 WP_000793769.1 hypothetical protein -
HF574_RS29115 (HF574_29850) 106733..107617 + 885 WP_000477209.1 hypothetical protein -
HF574_RS29120 (HF574_29855) 107683..107907 + 225 WP_001102700.1 class I ribonucleotide reductase maintenance protein YfaE -
HF574_RS29125 (HF574_29860) 107969..108358 + 390 WP_000026577.1 hypothetical protein -
HF574_RS29130 (HF574_29865) 108348..108800 + 453 WP_001176699.1 hypothetical protein -
HF574_RS29135 (HF574_29870) 109138..109329 + 192 WP_000651508.1 hypothetical protein -
HF574_RS29140 (HF574_29875) 109398..109751 + 354 WP_000994741.1 hypothetical protein -
HF574_RS29145 (HF574_29880) 109943..110287 + 345 WP_000209093.1 hypothetical protein -
HF574_RS29150 (HF574_29885) 110365..110667 + 303 WP_000410925.1 hypothetical protein -
HF574_RS29160 (HF574_29895) 112182..113708 + 1527 WP_228413705.1 DNA cytosine methyltransferase -
HF574_RS29165 (HF574_29900) 113769..114200 + 432 WP_000687894.1 hypothetical protein -
HF574_RS29170 (HF574_29905) 114274..114828 + 555 WP_001093868.1 hypothetical protein -
HF574_RS29175 (HF574_29910) 115061..115447 + 387 WP_000042274.1 hypothetical protein -
HF574_RS29180 (HF574_29915) 115535..117988 + 2454 WP_001187970.1 phosphoadenosine phosphosulfate reductase -
HF574_RS29185 (HF574_29920) 118190..118393 + 204 WP_000050848.1 hypothetical protein -
HF574_RS29190 (HF574_29925) 118465..119070 + 606 WP_000071870.1 5'-deoxynucleotidase -
HF574_RS29195 (HF574_29930) 119063..119332 + 270 WP_000184110.1 hypothetical protein -
HF574_RS29200 (HF574_29935) 119346..119564 + 219 WP_000260293.1 hypothetical protein -
HF574_RS29205 (HF574_29940) 119638..120195 + 558 WP_000064431.1 pyruvate dehydrogenase -
HF574_RS29210 (HF574_29945) 120270..121121 + 852 WP_000595210.1 hypothetical protein -
HF574_RS29215 (HF574_29950) 121579..121965 + 387 WP_001077335.1 hypothetical protein -
HF574_RS29220 (HF574_29955) 122143..123870 + 1728 WP_000122923.1 toprim domain-containing protein -
HF574_RS29225 (HF574_29960) 123857..124135 + 279 WP_000268337.1 hypothetical protein -
HF574_RS29230 (HF574_29965) 124208..124447 + 240 WP_000714162.1 permease -
HF574_RS29235 (HF574_29970) 124457..124573 + 117 WP_000338626.1 hypothetical protein -
HF574_RS29240 (HF574_29975) 124694..125068 + 375 WP_000868821.1 hypothetical protein -
HF574_RS29245 (HF574_29980) 125182..125907 + 726 WP_000988732.1 hypothetical protein -
HF574_RS29250 (HF574_29985) 126148..130302 + 4155 WP_014342219.1 Putative deoxyribonuclease RhsC VF
HF574_RS29255 (HF574_29990) 130299..130571 + 273 WP_000787563.1 MafI family immunity protein -
HF574_RS29260 (HF574_29995) 130576..130818 + 243 WP_000750746.1 hypothetical protein -
HF574_RS29265 (HF574_30000) 130866..131165 + 300 WP_011872911.1 hypothetical protein -
HF574_RS29270 (HF574_30005) 131332..131784 + 453 WP_000791469.1 hypothetical protein -
HF574_RS29275 (HF574_30010) 131800..132402 - 603 WP_000278322.1 hypothetical protein -
HF574_RS29280 (HF574_30015) 132664..132945 + 282 WP_000575657.1 hypothetical protein -
HF574_RS29285 (HF574_30020) 133244..133780 + 537 WP_000949433.1 hypothetical protein -
HF574_RS29290 (HF574_30025) 133783..134793 + 1011 WP_000543934.1 IS91 family transposase ISWz1 Transposase
HF574_RS29295 (HF574_30030) 134843..137848 - 3006 WP_001143759.1 Tn3 family transposase TnpA_Tn3 Transposase
HF574_RS29300 (HF574_30035) 138011..138568 + 558 WP_001217881.1 Tn3 family transposase TnpR_Tn3 Transposase
HF574_RS29305 (HF574_30040) 138691..139671 + 981 WP_013213985.1 IS481 family transposase ISKpn27 Transposase
HF574_RS29310 (HF574_30045) 139794..140396 + 603 WP_087497906.1 class A beta-lactamase -
HF574_RS29315 (HF574_30050) 140491..141372 + 882 WP_004199234.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
HF574_RS29320 (HF574_30055) 141622..142503 - 882 Protein_169 IS1182 family transposase ISKpn6 Transposase
HF574_RS29325 (HF574_30060) 142607..142903 - 297 WP_013213987.1 transcriptional regulator -
HF574_RS29330 (HF574_30065) 142949..143104 - 156 WP_013213988.1 hypothetical protein -
HF574_RS29335 (HF574_30070) 143232..143657 - 426 WP_013213989.1 antirestriction protein -
HF574_RS29340 (HF574_30075) 143768..144046 - 279 WP_013213990.1 hypothetical protein -
HF574_RS29345 (HF574_30080) 144580..145197 - 618 Protein_174 replication protein -
HF574_RS29350 (HF574_30085) 145907..146782 + 876 WP_001097010.1 DNA replication terminus site-binding protein -
HF574_RS29355 (HF574_30090) 146953..147993 + 1041 WP_000101568.1 DNA-binding protein -
HF574_RS29360 (HF574_30095) 148280..149791 + 1512 WP_000811656.1 UvrD-helicase domain-containing protein -
HF574_RS29365 (HF574_30100) 149902..150942 + 1041 WP_001326396.1 conjugal transfer protein TraF -
HF574_RS29370 (HF574_30105) 150944..152377 + 1434 WP_000256129.1 conjugal transfer protein TraH -
HF574_RS29375 (HF574_30110) 152390..156004 + 3615 WP_000534551.1 conjugal transfer protein TraG N-terminal domain-containing protein -
HF574_RS29380 (HF574_30115) 156042..156404 - 363 WP_000683483.1 hypothetical protein -
HF574_RS29385 (HF574_30120) 157120..157392 + 273 WP_000356489.1 helix-turn-helix domain-containing protein -
HF574_RS29390 (HF574_30125) 157392..157925 + 534 WP_000790610.1 transglycosylase SLT domain-containing protein -
HF574_RS29395 (HF574_30130) 157936..158544 + 609 WP_000891157.1 hypothetical protein -
HF574_RS29400 (HF574_30135) 158541..159092 + 552 WP_001020646.1 FlhC family transcriptional regulator -
HF574_RS29405 (HF574_30140) 159152..159571 - 420 WP_000651490.1 H-NS family nucleoid-associated regulatory protein -
HF574_RS29410 (HF574_30145) 159573..159866 - 294 WP_000919078.1 hypothetical protein -
HF574_RS29415 (HF574_30150) 159883..160866 - 984 WP_000077458.1 ParM/StbA family protein -
HF574_RS29420 (HF574_30155) 161365..161904 + 540 WP_001447712.1 conjugative transfer protein MobI(A/C) -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance