MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 89595 bp
Accession: NZ_CP076306 Location: 1..89595 Organism: Escherichia coli strain Survcare253 Replicon: plasmid pS253-NDM5
Accession: NZ_CP076306 Location: 1..89595 Organism: Escherichia coli strain Survcare253 Replicon: plasmid pS253-NDM5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KNN07_RS23275 (1301) | 1301..2041 | - | 741 | WP_001586233.1 | tyrosine-type recombinase/integrase | - |
| KNN07_RS23280 (2162) | 2162..2344 | - | 183 | WP_042004909.1 | hypothetical protein | - |
| KNN07_RS25065 (2411) | 2411..2701 | - | 291 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KNN07_RS23290 (2688) | 2688..2956 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| KNN07_RS23295 (3252) | 3252..3992 | - | 741 | WP_029702141.1 | IS91 family transposase ISMno23 | Transposase |
| KNN07_RS23305 (4945) | 4945..5394 | - | 450 | WP_029702172.1 | hypothetical protein | - |
| KNN07_RS23310 (5921) | 5921..6444 | + | 524 | Protein_8 | IS1 family transposase | - |
| KNN07_RS23315 (6536) | 6536..6814 | - | 279 | Protein_9 | type II toxin-antitoxin system toxin YacB | - |
| KNN07_RS25070 (6814) | 6814..6969 | - | 156 | Protein_10 | type II toxin-antitoxin system antitoxin YacA | - |
| KNN07_RS23320 (7073) | 7073..8405 | - | 1333 | Protein_11 | group II intron reverse transcriptase/maturase | - |
| KNN07_RS23325 (9022) | 9022..9882 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| KNN07_RS23330 (10065) | 10065..10622 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| KNN07_RS23335 (10924) | 10924..11688 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| KNN07_RS23340 (12181) | 12181..12765 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| KNN07_RS23345 (12765) | 12765..14003 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| KNN07_RS23350 (14000) | 14000..14905 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| KNN07_RS23355 (15027) | 15027..15731 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KNN07_RS23360 (15896) | 15896..16189 | + | 294 | Protein_19 | IS30 family transposase ISAba125 | Transposase |
| KNN07_RS23365 (16290) | 16290..17102 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| KNN07_RS23370 (17106) | 17106..17471 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| KNN07_RS23375 (17476) | 17476..18114 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| KNN07_RS25075 (18125) | 18125..18682 | - | 558 | Protein_23 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| KNN07_RS25080 (18782) | 18782..19156 | - | 375 | Protein_24 | protein-disulfide reductase DsbD family protein | - |
| KNN07_RS23385 (19469) | 19469..21010 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| KNN07_RS23390 (21415) | 21415..22254 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| KNN07_RS23395 (22248) | 22248..22595 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| KNN07_RS23400 (22712) | 22712..23550 | - | 839 | Protein_28 | Streptomycin 3''-adenylyltransferase | ARG |
| KNN07_RS23405 (23556) | 23556..23846 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| KNN07_RS23410 (23958) | 23958..24455 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| KNN07_RS23415 (24600) | 24600..24899 | + | 300 | Protein_31 | 60 kDa chaperonin | VF |
| KNN07_RS23420 (24900) | 24900..25253 | + | 354 | Protein_32 | 60 kDa chaperonin | VF |
| KNN07_RS23425 (25528) | 25528..27012 | + | 1485 | WP_022742855.1 | IS91 family transposase ISVsa3 | Transposase |
| KNN07_RS23430 (27251) | 27251..27637 | + | 387 | Protein_34 | mechanosensitive ion channel | - |
| KNN07_RS23435 (27665) | 27665..29200 | - | 1536 | WP_064760451.1 | Antiseptic resistance protein | ARG |
| KNN07_RS23440 (29595) | 29595..30275 | + | 681 | Protein_36 | IS91 family transposase ISAzo26 | Transposase |
| KNN07_RS23445 (30340) | 30340..31044 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KNN07_RS23450 (31110) | 31110..31655 | + | 546 | Protein_38 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KNN07_RS23455 (31691) | 31691..32106 | - | 416 | Protein_39 | IS1 family transposase IS1R | Transposase |
| KNN07_RS23460 (32355) | 32355..32756 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| KNN07_RS23465 (32689) | 32689..32946 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| KNN07_RS23470 (33039) | 33039..33692 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| KNN07_RS23475 (34631) | 34631..35488 | - | 858 | WP_163419524.1 | incFII family plasmid replication initiator RepA | - |
| KNN07_RS23480 (35481) | 35481..35555 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| KNN07_RS23485 (35791) | 35791..36048 | - | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| KNN07_RS23490 (36332) | 36332..36481 | - | 150 | WP_001367749.1 | Hok/Gef family protein | Toxin Detail |
| - (36525) | 36525..36586 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (36525) | 36525..36586 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (36525) | 36525..36586 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (36525) | 36525..36586 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| KNN07_RS25085 (36725) | 36725..37153 | - | 429 | WP_029702151.1 | hypothetical protein | - |
| KNN07_RS23500 (37366) | 37366..37935 | - | 570 | WP_029702150.1 | DUF2726 domain-containing protein | - |
| KNN07_RS23505 (38087) | 38087..38713 | - | 627 | WP_029702149.1 | NYN domain-containing protein | - |
| KNN07_RS23515 (39804) | 39804..40421 | + | 618 | Protein_51 | ISL3 family transposase ISEc38 | Transposase |
| KNN07_RS23520 (40885) | 40885..41892 | - | 1008 | WP_001232702.1 | LacI family DNA-binding transcriptional regulator | - |
| KNN07_RS23525 (41918) | 41918..43327 | - | 1410 | WP_039052598.1 | sucrose-6-phosphate hydrolase | - |
| KNN07_RS23530 (43327) | 43327..44697 | - | 1371 | WP_000344915.1 | sucrose-specific PTS transporter subunit IIBC | - |
| KNN07_RS23535 (44758) | 44758..46275 | - | 1518 | WP_039052597.1 | carbohydrate porin | - |
| KNN07_RS23540 (46443) | 46443..47363 | - | 921 | WP_039052596.1 | aminoimidazole riboside kinase | - |
| KNN07_RS25090 (47546) | 47546..47975 | + | 430 | Protein_57 | hypothetical protein | - |
| KNN07_RS23550 (48063) | 48063..48626 | - | 564 | WP_001377760.1 | class I SAM-dependent methyltransferase | - |
| KNN07_RS23555 (48674) | 48674..50035 | - | 1362 | WP_039052595.1 | DUF3560 domain-containing protein | - |
| KNN07_RS23560 (50087) | 50087..50316 | - | 230 | Protein_60 | hypothetical protein | - |
| KNN07_RS25095 (50831) | 50831..51127 | + | 297 | Protein_61 | hypothetical protein | - |
| KNN07_RS23565 (51269) | 51269..51460 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| KNN07_RS23570 (51509) | 51509..51934 | - | 426 | WP_061856959.1 | antirestriction protein | - |
| KNN07_RS23575 (52350) | 52350..52799 | - | 450 | Protein_64 | hypothetical protein | - |
| KNN07_RS23580 (52985) | 52985..53332 | + | 348 | WP_077877391.1 | hypothetical protein | - |
| KNN07_RS23585 (53423) | 53423..54120 | + | 698 | WP_103215986.1 | IS1-like element IS1A family transposase | - |
| KNN07_RS23590 (54141) | 54141..54374 | - | 234 | Protein_67 | sodium/glutamate symporter | - |
| KNN07_RS23595 (54818) | 54818..55138 | + | 321 | WP_000562370.1 | antibiotic biosynthesis monooxygenase | - |
| KNN07_RS23600 (55131) | 55131..55568 | + | 438 | WP_251126788.1 | amino acid-binding protein | - |
| KNN07_RS23610 (56861) | 56861..57547 | + | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| KNN07_RS23615 (57525) | 57525..58148 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| KNN07_RS23620 (58230) | 58230..59435 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| KNN07_RS23625 (59548) | 59548..60141 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| KNN07_RS23630 (60229) | 60229..60645 | + | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| KNN07_RS23635 (60655) | 60655..61410 | - | 756 | Protein_76 | IS4-like element ISVsa5 family transposase | - |
| KNN07_RS23640 (61481) | 61481..62601 | + | 1121 | WP_087758690.1 | IS3 family transposase ISSen4 | Transposase |
| KNN07_RS23645 (63573) | 63573..64361 | + | 789 | WP_224053116.1 | hypothetical protein | - |
| KNN07_RS23650 (64363) | 64363..66627 | + | 2265 | WP_039052447.1 | UvrD-helicase domain-containing protein | - |
| KNN07_RS23655 (66970) | 66970..67950 | + | 981 | WP_039052448.1 | IS5 family transposase ISKpn26 | Transposase |
| KNN07_RS23660 (68364) | 68364..69454 | + | 1091 | Protein_81 | translesion error-prone DNA polymerase V subunit UmuC | - |
| KNN07_RS23665 (69459) | 69459..69851 | - | 393 | WP_039052449.1 | plasmid partitioning/stability family protein | - |
| KNN07_RS23670 (69856) | 69856..70827 | - | 972 | WP_039052450.1 | plasmid segregation protein ParM | - |
| KNN07_RS23675 (71056) | 71056..71700 | + | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| KNN07_RS23680 (71694) | 71694..71969 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| KNN07_RS23685 (72107) | 72107..72867 | - | 761 | Protein_86 | tyrosine-type recombinase/integrase | - |
| KNN07_RS23695 (72935) | 72935..73543 | - | 609 | WP_039052451.1 | hypothetical protein | - |
| KNN07_RS23700 (73613) | 73613..73963 | - | 351 | WP_199613369.1 | hypothetical protein | - |
| KNN07_RS23705 (74641) | 74641..75636 | + | 996 | WP_000246635.1 | hypothetical protein | - |
| KNN07_RS23710 (75640) | 75640..76572 | + | 933 | WP_000991831.1 | S-4TM family putative pore-forming effector | - |
| KNN07_RS23720 (76865) | 76865..77953 | + | 1089 | Protein_91 | transcriptional regulator | - |
| KNN07_RS23725 (77946) | 77946..78824 | + | 879 | WP_225522546.1 | hypothetical protein | - |
| KNN07_RS23730 (78881) | 78881..80446 | - | 1566 | WP_001586226.1 | AAA family ATPase | - |
| KNN07_RS23735 (80733) | 80733..81245 | + | 513 | WP_001586228.1 | hypothetical protein | - |
| KNN07_RS23740 (81279) | 81279..82412 | - | 1134 | WP_000545985.1 | DUF3800 domain-containing protein | - |
| KNN07_RS25100 (82579) | 82579..82968 | - | 390 | WP_001403960.1 | hypothetical protein | - |
| KNN07_RS25105 (82914) | 82914..83351 | - | 438 | WP_001403959.1 | hypothetical protein | - |
| KNN07_RS23750 (83364) | 83364..83865 | - | 502 | Protein_98 | HEPN family nuclease | - |
| KNN07_RS23755 (84256) | 84256..86877 | + | 2622 | WP_001586230.1 | hypothetical protein | - |
| KNN07_RS25110 (87021) | 87021..87092 | - | 72 | Protein_100 | hypothetical protein | - |
| KNN07_RS23760 (87076) | 87076..87306 | + | 231 | WP_001261274.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| KNN07_RS23765 (87303) | 87303..87619 | + | 317 | Protein_102 | type II toxin-antitoxin system VapC family toxin | - |
| KNN07_RS23770 (87675) | 87675..87892 | - | 218 | Protein_103 | transposase | - |
| KNN07_RS23775 (87893) | 87893..88423 | - | 531 | WP_000348883.1 | GNAT family N-acetyltransferase | - |
| KNN07_RS23780 (88427) | 88427..88696 | - | 270 | WP_001275013.1 | DUF1778 domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|