MGE detailed information
MGE type: Conjugative plasmid MGE length: 127528 bp
Accession: NZ_CP076302 Location: 1..127528 Organism: Escherichia coli strain Survcare321 Replicon: plasmid p321-NDM5
Accession: NZ_CP076302 Location: 1..127528 Organism: Escherichia coli strain Survcare321 Replicon: plasmid p321-NDM5
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KNN06_RS24325 (1301) | 1301..2041 | - | 741 | WP_001586233.1 | tyrosine-type recombinase/integrase | - |
| KNN06_RS24330 (2162) | 2162..2344 | - | 183 | WP_042004909.1 | hypothetical protein | - |
| KNN06_RS26100 (2411) | 2411..2701 | - | 291 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KNN06_RS24340 (2688) | 2688..2956 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| KNN06_RS24345 (3252) | 3252..3992 | - | 741 | WP_029702141.1 | IS91 family transposase ISMno23 | Transposase |
| KNN06_RS24355 (4945) | 4945..5394 | - | 450 | WP_029702172.1 | hypothetical protein | - |
| KNN06_RS24360 (5921) | 5921..6444 | + | 524 | Protein_8 | IS1 family transposase | - |
| KNN06_RS24365 (6536) | 6536..6814 | - | 279 | Protein_9 | type II toxin-antitoxin system toxin YacB | - |
| KNN06_RS26105 (6814) | 6814..6969 | - | 156 | Protein_10 | type II toxin-antitoxin system antitoxin YacA | - |
| KNN06_RS24370 (7073) | 7073..8405 | - | 1333 | Protein_11 | group II intron reverse transcriptase/maturase | - |
| KNN06_RS24375 (9022) | 9022..9882 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| KNN06_RS24380 (10065) | 10065..10622 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| KNN06_RS24385 (10924) | 10924..11688 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| KNN06_RS24390 (12181) | 12181..12765 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| KNN06_RS24395 (12765) | 12765..14003 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| KNN06_RS24400 (14000) | 14000..14905 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| KNN06_RS24405 (15027) | 15027..15731 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KNN06_RS24410 (15896) | 15896..16189 | + | 294 | Protein_19 | IS30 family transposase ISAba125 | Transposase |
| KNN06_RS24415 (16290) | 16290..17102 | + | 813 | WP_023408309.1 | Metallo-beta-lactamase type 2 | ARG |
| KNN06_RS24420 (17106) | 17106..17471 | + | 366 | WP_004201167.1 | bleomycin binding protein Ble-MBL | - |
| KNN06_RS24425 (17476) | 17476..18114 | + | 639 | WP_004201168.1 | phosphoribosylanthranilate isomerase | - |
| KNN06_RS26110 (18125) | 18125..18682 | - | 558 | Protein_23 | twin-arginine translocation (TAT) pathway signal sequence domain protein | - |
| KNN06_RS26115 (18782) | 18782..19156 | - | 375 | Protein_24 | protein-disulfide reductase DsbD family protein | - |
| KNN06_RS24435 (19469) | 19469..21010 | - | 1542 | WP_000050481.1 | IS91 family transposase ISVsa3 | Transposase |
| KNN06_RS24440 (21415) | 21415..22254 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| KNN06_RS24445 (22248) | 22248..22595 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| KNN06_RS24450 (22712) | 22712..23550 | - | 839 | Protein_28 | Streptomycin 3''-adenylyltransferase | ARG |
| KNN06_RS24455 (23556) | 23556..23846 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| KNN06_RS24460 (23958) | 23958..24455 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| KNN06_RS24465 (24600) | 24600..24899 | + | 300 | Protein_31 | class 1 integron integrase IntI1 | - |
| KNN06_RS24470 (24900) | 24900..25253 | + | 354 | Protein_32 | TCP-1/cpn60 chaperonin family protein | - |
| KNN06_RS24475 (25528) | 25528..27012 | + | 1485 | WP_022742855.1 | IS91 family transposase | - |
| KNN06_RS24480 (27251) | 27251..27637 | + | 387 | Protein_34 | mechanosensitive ion channel | - |
| KNN06_RS24485 (27665) | 27665..29047 | - | 1383 | WP_252248920.1 | Antiseptic resistance protein | ARG |
| KNN06_RS24490 (29106) | 29106..29810 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KNN06_RS24495 (29876) | 29876..30421 | + | 546 | Protein_37 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KNN06_RS24500 (30457) | 30457..30872 | - | 416 | Protein_38 | IS1-like element IS1B family transposase | - |
| KNN06_RS24505 (31121) | 31121..31522 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| KNN06_RS24510 (31455) | 31455..31712 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| KNN06_RS24515 (31805) | 31805..32458 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| KNN06_RS24520 (32556) | 32556..32696 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| KNN06_RS24525 (33397) | 33397..34254 | - | 858 | WP_029702152.1 | incFII family plasmid replication initiator RepA | - |
| KNN06_RS24530 (34247) | 34247..34321 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| KNN06_RS24535 (34557) | 34557..34814 | - | 258 | WP_000083833.1 | replication regulatory protein RepA | - |
| KNN06_RS24540 (35098) | 35098..35247 | - | 150 | WP_001367749.1 | Hok/Gef family protein | Toxin Detail |
| - (35291) | 35291..35352 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (35291) | 35291..35352 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (35291) | 35291..35352 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| - (35291) | 35291..35352 | + | 62 | NuclAT_0 | - | Antitoxin Detail |
| KNN06_RS26120 (35491) | 35491..35919 | - | 429 | WP_029702151.1 | hypothetical protein | - |
| KNN06_RS24550 (36132) | 36132..36701 | - | 570 | WP_029702150.1 | DUF2726 domain-containing protein | - |
| KNN06_RS24555 (36853) | 36853..37479 | - | 627 | WP_029702149.1 | NYN domain-containing protein | - |
| KNN06_RS24560 (37891) | 37891..38100 | - | 210 | WP_039023209.1 | hypothetical protein | - |
| KNN06_RS24565 (38231) | 38231..38791 | - | 561 | WP_001567328.1 | fertility inhibition protein FinO | - |
| KNN06_RS24570 (38846) | 38846..39592 | - | 747 | WP_052273601.1 | conjugal transfer pilus acetylase TraX | - |
| KNN06_RS24575 (39620) | 39620..40366 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| KNN06_RS24580 (40381) | 40381..41922 | - | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| KNN06_RS24585 (42198) | 42198..47468 | - | 5271 | WP_039052472.1 | Multifunctional conjugation protein TraI | Relaxase |
| KNN06_RS24590 (47550) | 47550..47777 | + | 228 | WP_039023146.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| KNN06_RS24595 (47777) | 47777..48175 | + | 399 | WP_039023147.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KNN06_RS24600 (48184) | 48184..50373 | - | 2190 | WP_073961454.1 | type IV conjugative transfer system coupling protein TraD | - |
| KNN06_RS24605 (50626) | 50626..51357 | - | 732 | WP_000850422.1 | conjugal transfer complement resistance protein TraT | - |
| KNN06_RS24610 (51389) | 51389..51886 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| KNN06_RS24615 (51905) | 51905..54724 | - | 2820 | WP_039023149.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| KNN06_RS24620 (54721) | 54721..56094 | - | 1374 | WP_039023150.1 | conjugal transfer pilus assembly protein TraH | - |
| KNN06_RS24625 (56094) | 56094..56456 | - | 363 | WP_071550055.1 | P-type conjugative transfer protein TrbJ | - |
| KNN06_RS24630 (56386) | 56386..56931 | - | 546 | WP_039052470.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| KNN06_RS24635 (56918) | 56918..57202 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| KNN06_RS24640 (57321) | 57321..57668 | - | 348 | WP_001287894.1 | conjugal transfer protein TrbA | - |
| KNN06_RS24645 (57684) | 57684..58427 | - | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| KNN06_RS24650 (58420) | 58420..58677 | - | 258 | WP_039023152.1 | conjugal transfer protein TrbE | - |
| KNN06_RS24655 (58704) | 58704..60566 | - | 1863 | WP_224053115.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| KNN06_RS24660 (60802) | 60802..61182 | - | 381 | WP_039052469.1 | hypothetical protein | - |
| KNN06_RS24665 (61179) | 61179..61817 | - | 639 | WP_039052468.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| KNN06_RS24670 (61826) | 61826..62818 | - | 993 | WP_000830835.1 | conjugal transfer pilus assembly protein TraU | - |
| KNN06_RS24675 (62815) | 62815..63447 | - | 633 | WP_039052467.1 | type-F conjugative transfer system protein TraW | - |
| KNN06_RS24680 (63444) | 63444..63830 | - | 387 | WP_000099693.1 | type-F conjugative transfer system protein TrbI | - |
| KNN06_RS24685 (63827) | 63827..66454 | - | 2628 | WP_001064265.1 | type IV secretion system protein TraC | - |
| KNN06_RS24690 (66614) | 66614..66835 | - | 222 | WP_001278685.1 | conjugal transfer protein TraR | - |
| KNN06_RS24695 (66970) | 66970..67485 | - | 516 | WP_039052466.1 | type IV conjugative transfer system lipoprotein TraV | - |
| KNN06_RS24700 (67482) | 67482..67733 | - | 252 | WP_039052465.1 | conjugal transfer protein TrbG | - |
| KNN06_RS24705 (67726) | 67726..68046 | - | 321 | WP_001057302.1 | conjugal transfer protein TrbD | - |
| KNN06_RS24710 (68033) | 68033..68593 | - | 561 | WP_039052464.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| KNN06_RS24715 (68583) | 68583..70034 | - | 1452 | WP_039052463.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| KNN06_RS24720 (70034) | 70034..70762 | - | 729 | WP_039052462.1 | type-F conjugative transfer system secretin TraK | - |
| KNN06_RS24725 (70749) | 70749..71315 | - | 567 | WP_039052461.1 | type IV conjugative transfer system protein TraE | - |
| KNN06_RS24730 (71337) | 71337..71648 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| KNN06_RS24735 (71653) | 71653..72015 | - | 363 | WP_039052460.1 | type IV conjugative transfer system pilin TraA | - |
| KNN06_RS24740 (72048) | 72048..72449 | - | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| KNN06_RS24745 (72542) | 72542..73231 | - | 690 | WP_061856953.1 | conjugal transfer transcriptional regulator TraJ | - |
| KNN06_RS24750 (73418) | 73418..73801 | - | 384 | WP_061856954.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| KNN06_RS24755 (74133) | 74133..74723 | + | 591 | WP_286675354.1 | hypothetical protein | VF |
| KNN06_RS24760 (75019) | 75019..75840 | - | 822 | WP_061856956.1 | DUF932 domain-containing protein | - |
| KNN06_RS24765 (75959) | 75959..76246 | - | 288 | WP_061856957.1 | hypothetical protein | - |
| KNN06_RS24770 (76547) | 76547..76875 | + | 329 | Protein_92 | hypothetical protein | - |
| KNN06_RS24775 (76866) | 76866..76997 | + | 132 | Protein_93 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KNN06_RS24785 (77947) | 77947..78564 | + | 618 | Protein_95 | ISL3 family transposase ISEc38 | Transposase |
| KNN06_RS24790 (79028) | 79028..80035 | - | 1008 | WP_001232702.1 | LacI family DNA-binding transcriptional regulator | - |
| KNN06_RS24795 (80061) | 80061..81470 | - | 1410 | WP_039052598.1 | sucrose-6-phosphate hydrolase | - |
| KNN06_RS24800 (81470) | 81470..82840 | - | 1371 | WP_000344915.1 | sucrose-specific PTS transporter subunit IIBC | - |
| KNN06_RS24805 (82901) | 82901..84418 | - | 1518 | WP_039052597.1 | carbohydrate porin | - |
| KNN06_RS24810 (84586) | 84586..85506 | - | 921 | WP_039052596.1 | aminoimidazole riboside kinase | - |
| KNN06_RS26125 (85689) | 85689..86118 | + | 430 | Protein_101 | hypothetical protein | - |
| KNN06_RS24820 (86206) | 86206..86769 | - | 564 | WP_001377760.1 | class I SAM-dependent methyltransferase | - |
| KNN06_RS24825 (86817) | 86817..88178 | - | 1362 | WP_039052595.1 | DUF3560 domain-containing protein | - |
| KNN06_RS24830 (88230) | 88230..88459 | - | 230 | Protein_104 | hypothetical protein | - |
| KNN06_RS26130 (88974) | 88974..89270 | + | 297 | Protein_105 | hypothetical protein | - |
| KNN06_RS24835 (89412) | 89412..89603 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| KNN06_RS24840 (89652) | 89652..90077 | - | 426 | WP_061856959.1 | antirestriction protein | - |
| KNN06_RS24845 (90493) | 90493..90942 | - | 450 | Protein_108 | hypothetical protein | - |
| KNN06_RS24850 (91128) | 91128..91475 | + | 348 | WP_077877391.1 | hypothetical protein | - |
| KNN06_RS24855 (91513) | 91513..92166 | + | 654 | WP_039052615.1 | DUF5710 domain-containing protein | - |
| KNN06_RS24860 (92280) | 92280..92977 | + | 698 | WP_103215986.1 | IS1 family transposase IS1G | Transposase |
| KNN06_RS24865 (92998) | 92998..93231 | - | 234 | Protein_112 | sodium/glutamate symporter | - |
| KNN06_RS24870 (93675) | 93675..93995 | + | 321 | WP_000562370.1 | antibiotic biosynthesis monooxygenase | - |
| KNN06_RS24875 (93988) | 93988..94374 | + | 387 | WP_000460651.1 | hypothetical protein | - |
| KNN06_RS24880 (94382) | 94382..95068 | + | 687 | WP_001284954.1 | winged helix-turn-helix domain-containing protein | - |
| KNN06_RS24885 (95046) | 95046..95669 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| KNN06_RS24890 (95751) | 95751..96956 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| KNN06_RS24895 (97069) | 97069..97662 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| KNN06_RS24900 (97750) | 97750..98166 | + | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| KNN06_RS24905 (98176) | 98176..99393 | - | 1218 | WP_061856962.1 | IS4 family transposase IS10R | Transposase |
| KNN06_RS24910 (99415) | 99415..100535 | + | 1121 | WP_087758690.1 | IS3 family transposase ISSen4 | Transposase |
| KNN06_RS24915 (101506) | 101506..102294 | + | 789 | WP_224053116.1 | hypothetical protein | - |
| KNN06_RS24920 (102296) | 102296..104560 | + | 2265 | WP_039052447.1 | UvrD-helicase domain-containing protein | - |
| KNN06_RS24925 (104903) | 104903..105883 | + | 981 | WP_039052448.1 | IS5 family transposase ISKpn26 | Transposase |
| KNN06_RS24930 (106297) | 106297..107387 | + | 1091 | Protein_125 | translesion error-prone DNA polymerase V subunit UmuC | - |
| KNN06_RS24935 (107392) | 107392..107784 | - | 393 | WP_039052449.1 | plasmid partitioning/stability family protein | - |
| KNN06_RS24940 (107789) | 107789..108760 | - | 972 | WP_039052450.1 | plasmid segregation protein ParM | - |
| KNN06_RS24945 (108989) | 108989..109633 | + | 645 | WP_000633913.1 | division plane positioning ATPase MipZ | - |
| KNN06_RS24950 (109627) | 109627..109902 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| KNN06_RS24955 (110040) | 110040..110800 | - | 761 | Protein_130 | tyrosine-type recombinase/integrase | - |
| KNN06_RS24965 (110868) | 110868..111476 | - | 609 | WP_039052451.1 | hypothetical protein | - |
| KNN06_RS24970 (111546) | 111546..111896 | - | 351 | WP_039052452.1 | hypothetical protein | - |
| KNN06_RS24975 (112574) | 112574..113569 | + | 996 | WP_000246635.1 | hypothetical protein | - |
| KNN06_RS24980 (113573) | 113573..114505 | + | 933 | WP_000991831.1 | S-4TM family putative pore-forming effector | - |
| KNN06_RS24990 (114798) | 114798..115886 | + | 1089 | Protein_135 | transcriptional regulator | - |
| KNN06_RS24995 (115879) | 115879..116757 | + | 879 | WP_225522546.1 | hypothetical protein | - |
| KNN06_RS25000 (116814) | 116814..118379 | - | 1566 | WP_001586226.1 | AAA family ATPase | - |
| KNN06_RS25005 (118690) | 118690..119178 | + | 489 | WP_024187433.1 | hypothetical protein | - |
| KNN06_RS25010 (119212) | 119212..120345 | - | 1134 | WP_000545985.1 | DUF3800 domain-containing protein | - |
| KNN06_RS26135 (120512) | 120512..120901 | - | 390 | WP_001403960.1 | hypothetical protein | - |
| KNN06_RS26140 (120847) | 120847..121284 | - | 438 | WP_001403959.1 | hypothetical protein | - |
| KNN06_RS25020 (121297) | 121297..121798 | - | 502 | Protein_142 | HEPN family nuclease | - |
| KNN06_RS25025 (122189) | 122189..124810 | + | 2622 | WP_001586230.1 | hypothetical protein | - |
| KNN06_RS26145 (124954) | 124954..125025 | - | 72 | Protein_144 | hypothetical protein | - |
| KNN06_RS25030 (125009) | 125009..125239 | + | 231 | WP_001261274.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| KNN06_RS25035 (125236) | 125236..125552 | + | 317 | Protein_146 | type II toxin-antitoxin system VapC family toxin | - |
| KNN06_RS25040 (125608) | 125608..125825 | - | 218 | Protein_147 | transposase | - |
| KNN06_RS25045 (125826) | 125826..126356 | - | 531 | WP_000348883.1 | GNAT family N-acetyltransferase | - |
| KNN06_RS25050 (126360) | 126360..126629 | - | 270 | WP_001275013.1 | DUF1778 domain-containing protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|