MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 108031 bp
Accession: NZ_CP075057 Location: 1..108031 Organism: Escherichia coli strain TCM_B_2 Replicon: plasmid pB2_2
Accession: NZ_CP075057 Location: 1..108031 Organism: Escherichia coli strain TCM_B_2 Replicon: plasmid pB2_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H4F95_RS01090 (1) | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| H4F95_RS01095 (1263) | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| H4F95_RS01100 (2124) | 2124..2306 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| H4F95_RS26255 (2373) | 2373..2662 | - | 290 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| H4F95_RS01105 (2649) | 2649..2917 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| H4F95_RS01110 (3449) | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| H4F95_RS01115 (4651) | 4651..4779 | + | 129 | Protein_6 | IS481 family transposase | - |
| H4F95_RS01120 (4814) | 4814..5002 | - | 189 | Protein_7 | hypothetical protein | - |
| H4F95_RS01125 (5050) | 5050..5747 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| H4F95_RS01130 (5938) | 5938..6531 | + | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| H4F95_RS01135 (6644) | 6644..7849 | - | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| H4F95_RS01140 (7931) | 7931..8554 | + | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| H4F95_RS01145 (8532) | 8532..8651 | - | 120 | Protein_12 | transcriptional regulator | - |
| H4F95_RS01155 (9524) | 9524..10078 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| H4F95_RS01160 (10222) | 10222..10926 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| H4F95_RS01165 (10991) | 10991..11671 | - | 681 | Protein_16 | class 1 integron integrase IntI1 | - |
| H4F95_RS01170 (11829) | 11829..12302 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| H4F95_RS01175 (12433) | 12433..13221 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| H4F95_RS01180 (13427) | 13427..13774 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| H4F95_RS01185 (13768) | 13768..14355 | + | 588 | Protein_20 | dihydropteroate synthase | - |
| H4F95_RS01190 (14421) | 14421..15125 | + | 705 | WP_001067858.1 | IS6-like element IS26 family transposase | - |
| H4F95_RS01195 (15254) | 15254..16018 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| H4F95_RS01200 (16511) | 16511..17095 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| H4F95_RS01205 (17095) | 17095..18333 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| H4F95_RS01210 (18330) | 18330..19235 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| H4F95_RS01215 (19357) | 19357..20061 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| H4F95_RS01220 (20220) | 20220..20501 | - | 282 | Protein_27 | transposase zinc-binding domain-containing protein | - |
| H4F95_RS01225 (20648) | 20648..21508 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| H4F95_RS01230 (21691) | 21691..22029 | - | 339 | Protein_29 | Tn3 family transposase TnpR_Tn3 | Transposase |
| H4F95_RS01235 (22093) | 22093..22797 | + | 705 | WP_001067855.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| H4F95_RS01240 (22858) | 22858..23694 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| H4F95_RS01245 (23694) | 23694..24497 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| H4F95_RS01250 (24558) | 24558..25373 | - | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| H4F95_RS01255 (25681) | 25681..26532 | - | 852 | WP_000240536.1 | replication protein C, IncQ-type | - |
| H4F95_RS01260 (26519) | 26519..27238 | - | 720 | Protein_35 | helicase RepA family protein | - |
| H4F95_RS01265 (27288) | 27288..27764 | - | 477 | Protein_36 | IS6-like element IS26 family transposase | - |
| H4F95_RS01270 (27818) | 27818..28522 | - | 705 | WP_213206437.1 | IS6-like element IS26 family transposase | - |
| H4F95_RS01275 (28559) | 28559..29686 | - | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| H4F95_RS01280 (29737) | 29737..29964 | - | 228 | WP_000248278.1 | hypothetical protein | - |
| H4F95_RS01285 (29988) | 29988..30179 | + | 192 | WP_000951934.1 | hypothetical protein | - |
| H4F95_RS01290 (30661) | 30661..31203 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| H4F95_RS01295 (31216) | 31216..32076 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| H4F95_RS01300 (32219) | 32219..33181 | + | 963 | Protein_43 | IS4 family transposase IS10R | Transposase |
| H4F95_RS01305 (33291) | 33291..34196 | + | 906 | Protein_44 | IS4 family transposase IS10R | Transposase |
| H4F95_RS01310 (34245) | 34245..34949 | - | 705 | WP_001067858.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| H4F95_RS01315 (35013) | 35013..35351 | + | 339 | Protein_46 | Tn3 family transposase TnpR_Tn3 | Transposase |
| H4F95_RS01320 (35534) | 35534..36394 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| H4F95_RS01325 (36544) | 36544..36642 | - | 99 | Protein_48 | IS1 family transposase | - |
| H4F95_RS01330 (36671) | 36671..37981 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| H4F95_RS01335 (38266) | 38266..38667 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| H4F95_RS01340 (38600) | 38600..38857 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| H4F95_RS01345 (38950) | 38950..39603 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| H4F95_RS01350 (39701) | 39701..39841 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| H4F95_RS01355 (40542) | 40542..41399 | - | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| H4F95_RS01360 (41392) | 41392..41466 | - | 75 | WP_014966221.1 | RepA leader peptide Tap | - |
| H4F95_RS01370 (41828) | 41828..43369 | + | 1542 | WP_002431311.1 | IS21 family transposase ISEc12 | Transposase |
| H4F95_RS01375 (43384) | 43384..44130 | + | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| H4F95_RS01380 (44290) | 44290..44544 | - | 255 | WP_000083850.1 | replication regulatory protein RepA | - |
| H4F95_RS01385 (44841) | 44841..44975 | - | 135 | WP_023144756.1 | Hok/Gef family protein | Toxin Detail |
| - (45020) | 45020..45080 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| - (45020) | 45020..45080 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| - (45020) | 45020..45080 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| - (45020) | 45020..45080 | + | 61 | NuclAT_1 | - | Antitoxin Detail |
| H4F95_RS01390 (45047) | 45047..45333 | - | 287 | Protein_60 | DUF2726 domain-containing protein | - |
| H4F95_RS01395 (45846) | 45846..46058 | - | 213 | WP_013023861.1 | hypothetical protein | - |
| H4F95_RS01400 (46189) | 46189..46749 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| H4F95_RS01405 (46804) | 46804..47550 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| H4F95_RS01410 (47570) | 47570..52840 | - | 5271 | WP_001617867.1 | Multifunctional conjugation protein TraI | Relaxase |
| H4F95_RS01415 (52840) | 52840..55047 | - | 2208 | WP_021547900.1 | type IV conjugative transfer system coupling protein TraD | - |
| H4F95_RS01420 (55044) | 55044..55823 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| H4F95_RS01425 (56026) | 56026..56757 | - | 732 | WP_000850429.1 | conjugal transfer complement resistance protein TraT | - |
| H4F95_RS01430 (56789) | 56789..57286 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| H4F95_RS01435 (57305) | 57305..60124 | - | 2820 | WP_001007062.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| H4F95_RS01440 (60121) | 60121..61494 | - | 1374 | WP_000944328.1 | conjugal transfer pilus assembly protein TraH | - |
| H4F95_RS01445 (61481) | 61481..61873 | - | 393 | WP_000659962.1 | F-type conjugal transfer protein TrbF | - |
| H4F95_RS01450 (61854) | 61854..62201 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| H4F95_RS01455 (62131) | 62131..62676 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H4F95_RS01460 (62663) | 62663..62947 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H4F95_RS01465 (63074) | 63074..63394 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| H4F95_RS01475 (64194) | 64194..64655 | - | 462 | Protein_77 | IS3 family transposase IS150 | Transposase |
| - (64701) | 64701..64803 | - | 103 | NuclAT_0 | - | - |
| - (64701) | 64701..64803 | - | 103 | NuclAT_0 | - | - |
| - (64701) | 64701..64803 | - | 103 | NuclAT_0 | - | - |
| - (64701) | 64701..64803 | - | 103 | NuclAT_0 | - | - |
| H4F95_RS01480 (64772) | 64772..65534 | - | 763 | Protein_78 | plasmid SOS inhibition protein A | - |
| H4F95_RS01485 (65531) | 65531..65965 | - | 435 | WP_000845940.1 | conjugation system SOS inhibitor PsiB | - |
| H4F95_RS01490 (66020) | 66020..67978 | - | 1959 | WP_000117179.1 | ParB/RepB/Spo0J family partition protein | - |
| H4F95_RS01495 (68044) | 68044..68277 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| H4F95_RS01500 (68340) | 68340..68837 | - | 498 | WP_042045560.1 | single-stranded DNA-binding protein | - |
| H4F95_RS01505 (68987) | 68987..70888 | - | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| H4F95_RS26260 (71566) | 71566..71772 | - | 207 | WP_000547975.1 | hypothetical protein | - |
| H4F95_RS26265 (72013) | 72013..72264 | - | 252 | WP_071579736.1 | hypothetical protein | - |
| H4F95_RS01510 (72183) | 72183..72389 | - | 207 | WP_001774176.1 | hypothetical protein | - |
| H4F95_RS01515 (72415) | 72415..72978 | - | 564 | WP_001348621.1 | class I SAM-dependent methyltransferase | - |
| H4F95_RS01520 (73026) | 73026..74387 | - | 1362 | WP_000170714.1 | DUF3560 domain-containing protein | - |
| H4F95_RS01525 (74439) | 74439..74669 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| H4F95_RS01530 (75704) | 75704..75895 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| H4F95_RS01535 (75892) | 75892..76314 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| H4F95_RS01540 (76361) | 76361..76786 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| H4F95_RS01545 (77203) | 77203..77979 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| H4F95_RS01550 (78030) | 78030..78548 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| H4F95_RS01555 (78478) | 78478..78699 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| H4F95_RS01560 (78700) | 78700..79383 | - | 684 | WP_000086185.1 | DNA methylase | - |
| H4F95_RS01565 (79460) | 79460..79771 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| H4F95_RS01570 (79768) | 79768..80670 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| H4F95_RS01575 (81537) | 81537..82508 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| H4F95_RS01580 (82508) | 82508..83674 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| H4F95_RS01585 (84262) | 84262..85017 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| H4F95_RS01590 (85791) | 85791..86597 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| H4F95_RS01595 (86598) | 86598..86903 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| H4F95_RS01600 (86905) | 86905..87123 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| H4F95_RS01605 (87757) | 87757..87954 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| H4F95_RS01610 (87951) | 87951..88235 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| H4F95_RS01615 (88255) | 88255..89388 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| H4F95_RS01620 (89651) | 89651..92770 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| H4F95_RS01625 (93077) | 93077..93307 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| H4F95_RS01630 (93304) | 93304..93720 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| H4F95_RS01635 (93882) | 93882..96020 | - | 2139 | WP_202757506.1 | AAA family ATPase | - |
| H4F95_RS01640 (96485) | 96485..97498 | + | 1014 | WP_085674723.1 | nucleotidyltransferase | - |
| H4F95_RS01645 (97541) | 97541..98434 | + | 894 | WP_001553853.1 | S-4TM family putative pore-forming effector | - |
| H4F95_RS01655 (99482) | 99482..102598 | - | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| H4F95_RS01660 (102720) | 102720..103991 | - | 1272 | WP_023142242.1 | restriction endonuclease subunit S | - |
| H4F95_RS01665 (103988) | 103988..105544 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| H4F95_RS01670 (105727) | 105727..105948 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| H4F95_RS01675 (105948) | 105948..106328 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| H4F95_RS01680 (106333) | 106333..106512 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| H4F95_RS01685 (106540) | 106540..106818 | + | 279 | Protein_121 | pdcB | - |
| H4F95_RS01690 (106823) | 106823..107236 | + | 414 | Protein_122 | IS3 family transposase ISLad1 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|