MGE detailed information

MGE type: Conjugative plasmid        MGE length: 142024 bp
Accession: NZ_CP074554        Location: 1..142024         Organism: Klebsiella pneumoniae strain S37_CRE38       Replicon: plasmid pCRE38_1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHW02_RS26800 (KHW02_26735) 1..1020 + 1020 WP_032408924.1 plasmid replication initiator RepA -
KHW02_RS26805 (KHW02_26740) 2036..2941 + 906 WP_022644917.1 hypothetical protein -
KHW02_RS26810 (KHW02_26745) 3310..3891 + 582 WP_032408940.1 DUF2913 family protein -
KHW02_RS26815 (KHW02_26750) 3931..4884 - 954 WP_022644915.1 Recombination-promoting nuclease RpnA VF
KHW02_RS26820 (KHW02_26755) 4992..5579 - 588 WP_022644914.1 Tn3 family transposase TnpR_ISSba14 Transposase
KHW02_RS26825 (KHW02_26760) 6119..6637 + 519 WP_022644913.1 hypothetical protein -
KHW02_RS26830 (KHW02_26765) 6967..7614 + 648 WP_022644912.1 AAA family ATPase -
KHW02_RS26835 (KHW02_26770) 7605..7880 + 276 WP_032072061.1 hypothetical protein -
KHW02_RS26840 (KHW02_26775) 8073..8273 - 201 WP_022644911.1 hypothetical protein -
KHW02_RS26845 (KHW02_26780) 8375..9646 - 1272 WP_022644910.1 Y-family DNA polymerase -
KHW02_RS26850 (KHW02_26785) 9658..10119 - 462 WP_022644909.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
KHW02_RS26855 (KHW02_26790) 10104..10349 - 246 WP_022644908.1 DinI-like family protein -
KHW02_RS26860 (KHW02_26795) 10553..10783 + 231 WP_022644907.1 hypothetical protein -
KHW02_RS26865 (KHW02_26800) 11219..12151 + 933 WP_022644906.1 DUF1281 domain-containing protein -
KHW02_RS26870 (KHW02_26805) 12186..12419 + 234 Protein_14 hypothetical protein -
KHW02_RS26875 (KHW02_26810) 12416..12751 + 336 WP_022644905.1 hypothetical protein -
KHW02_RS26880 12896..13065 + 170 Protein_16 hypothetical protein -
KHW02_RS26885 (KHW02_26820) 13137..13838 + 702 WP_004152355.1 DNA methylase -
KHW02_RS26890 (KHW02_26825) 13838..14059 + 222 WP_022644904.1 hypothetical protein -
KHW02_RS26895 (KHW02_26830) 14069..14488 + 420 WP_022644903.1 DUF1380 family protein -
KHW02_RS26900 (KHW02_26835) 14542..15309 + 768 WP_032072058.1 hypothetical protein -
KHW02_RS26905 (KHW02_26840) 15990..16418 + 429 WP_025404028.1 antirestriction protein -
KHW02_RS26910 (KHW02_26845) 16463..16969 + 507 WP_022644900.1 antirestriction protein ArdA -
KHW02_RS26915 (KHW02_26850) 17012..17203 + 192 WP_022644899.1 hypothetical protein -
KHW02_RS26920 (KHW02_26855) 17397..17651 + 255 WP_025404029.1 DNA polymerase III subunit theta -
KHW02_RS26925 (KHW02_26860) 17687..18007 + 321 WP_022644897.1 hypothetical protein -
KHW02_RS26930 (KHW02_26865) 18682..19224 + 543 WP_022644896.1 single-stranded DNA-binding protein -
KHW02_RS26935 (KHW02_26870) 19273..19521 + 249 WP_022644895.1 DUF905 domain-containing protein -
KHW02_RS26940 (KHW02_26875) 19590..21590 + 2001 WP_022644894.1 ParB/RepB/Spo0J family partition protein -
KHW02_RS26945 (KHW02_26880) 21635..22066 + 432 WP_015632482.1 conjugation system SOS inhibitor PsiB -
KHW02_RS26950 (KHW02_26885) 22063..22791 + 729 WP_022644893.1 plasmid SOS inhibition protein A -
KHW02_RS26955 (KHW02_26890) 22788..23114 + 327 WP_015632484.1 hypothetical protein -
KHW02_RS26960 (KHW02_26895) 23303..24678 + 1376 WP_087439983.1 IS3 family transposase ISKpn8 Transposase
KHW02_RS26965 (KHW02_26900) 24848..25888 + 1041 WP_022644891.1 ATP-binding protein -
KHW02_RS26970 (KHW02_26905) 25866..28376 + 2511 WP_022644890.1 S8 family peptidase -
KHW02_RS26975 (KHW02_26910) 28810..30342 - 1533 WP_015065592.1 IS3 family transposase ISKpn38 Transposase
KHW02_RS26980 (KHW02_26915) 30431..31771 + 1341 WP_004196353.1 ISNCY family transposase ISCARN112 Transposase
KHW02_RS26985 (KHW02_26920) 32027..32449 - 423 WP_032072095.1 nickel resistance OB fold protein NcrY -
KHW02_RS26990 (KHW02_26925) 32611..33741 - 1131 WP_004196366.1 Ni(II)/Co(II) efflux transporter permease subunit NcrC -
KHW02_RS26995 (KHW02_26930) 33754..34023 - 270 WP_004196355.1 nickel-sensing transcriptional repressor NcrB -
KHW02_RS27000 (KHW02_26935) 34129..35427 - 1299 WP_004196314.1 MFS transporter -
KHW02_RS27005 (KHW02_26940) 35661..36419 - 759 WP_004196325.1 hypothetical protein -
KHW02_RS27010 (KHW02_26945) 36473..37393 - 921 WP_004196315.1 hypothetical protein -
KHW02_RS27015 (KHW02_26950) 37456..37827 - 372 WP_004196359.1 hypothetical protein -
KHW02_RS27020 (KHW02_26955) 37952..38144 - 193 Protein_44 MFS transporter -
KHW02_RS27025 38174..38557 + 384 WP_022644889.1 hypothetical protein -
KHW02_RS27030 (KHW02_26965) 38739..40058 + 1320 WP_004152397.1 IS1182 family transposase ISKpn6 Transposase
KHW02_RS27035 (KHW02_26970) 40308..41189 - 882 WP_004152396.1 Carbapenem-hydrolyzing beta-lactamase KPC ARG
KHW02_RS27040 (KHW02_26975) 41508..42287 - 780 WP_004152394.1 IS21 family transposase ISKpn7 Transposase
KHW02_RS27045 (KHW02_26980) 42284..43309 - 1026 WP_004199214.1 IS21 family transposase ISKpn7 Transposase
KHW02_RS27050 (KHW02_26985) 43416..46445 - 3030 WP_004152392.1 Tn3 family transposase ISPsy42 Transposase
KHW02_RS27055 (KHW02_26990) 46555..48270 + 1716 WP_004152391.1 Tn3-like element Tn4401 family resolvase TnpR -
KHW02_RS27060 (KHW02_26995) 48322..49221 - 900 Protein_52 Tn3 family transposase TnpA_Tn3 Transposase
KHW02_RS27065 (KHW02_27000) 49385..49942 + 558 WP_001217881.1 Tn3 family transposase TnpR_Tn3 Transposase
KHW02_RS27070 (KHW02_27005) 50176..50730 + 555 WP_063840280.1 Aminoglycoside N(6')-acetyltransferase type 1 ARG
KHW02_RS27075 (KHW02_27010) 50800..51588 + 789 WP_001206315.1 Streptomycin 3''-adenylyltransferase ARG
KHW02_RS27080 (KHW02_27015) 51648..52472 + 825 WP_000722315.1 Beta-lactamase OXA-18 ARG
KHW02_RS27085 (KHW02_27020) 52672..52989 + 318 Protein_57 Tn3 family transposase TnpR_Tn3 Transposase
KHW02_RS27090 (KHW02_27025) 53172..54032 + 861 WP_000027057.1 Beta-lactamase TEM ARG
KHW02_RS27095 (KHW02_27030) 54242..54646 + 405 Protein_59 IS91 family transposase ISPps1 Transposase
KHW02_RS27100 (KHW02_27035) 54753..55589 - 837 WP_000480968.1 hypothetical protein ARG
KHW02_RS27105 (KHW02_27040) 55589..56392 - 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
KHW02_RS27110 (KHW02_27045) 56453..57268 - 816 WP_001043260.1 Dihydropteroate synthase ARG
KHW02_RS27115 57598..57684 + 87 Protein_63 Arm DNA-binding domain-containing protein -
KHW02_RS27120 (KHW02_27055) 57956..58960 - 1005 WP_000427619.1 IS110 family transposase IS5075 Transposase
KHW02_RS27125 (KHW02_27060) 59039..60805 - 1767 Protein_65 Tn3 family transposase TnpA_ISPa38 Transposase
KHW02_RS27130 (KHW02_27065) 60857..61561 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
KHW02_RS27135 (KHW02_27070) 61552..61902 + 351 WP_032072070.1 TrbM/KikA/MpfK family conjugal transfer protein -
KHW02_RS27140 (KHW02_27075) 62016..62249 + 234 WP_001191790.1 hypothetical protein -
KHW02_RS27145 (KHW02_27080) 62299..62946 + 648 WP_012561184.1 restriction endonuclease -
KHW02_RS27150 (KHW02_27085) 62951..63157 + 207 WP_001749967.1 hypothetical protein -
KHW02_RS27155 (KHW02_27090) 63168..63440 - 273 Protein_71 IS1 family transposase IS1X2 Transposase
KHW02_RS27160 (KHW02_27095) 63539..64972 + 1434 WP_001288432.1 DNA cytosine methyltransferase -
KHW02_RS27165 (KHW02_27100) 65006..66220 - 1215 WP_004098817.1 type II site-specific deoxyribonuclease -
KHW02_RS27170 (KHW02_27105) 66276..66341 + 66 Protein_74 EAL domain-containing protein -
KHW02_RS27175 (KHW02_27110) 66481..67245 - 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
KHW02_RS27180 67363..67428 - 66 Protein_76 hypothetical protein Relaxase
KHW02_RS27185 67538..67654 - 117 Protein_77 hypothetical protein Relaxase
KHW02_RS27190 (KHW02_27120) 67875..68348 - 474 WP_004201280.1 Dihydrofolate reductase type 1 ARG
KHW02_RS27195 (KHW02_27125) 68504..69271 + 768 Protein_79 IS91 family transposase ISAzo26 Transposase
KHW02_RS27200 (KHW02_27130) 69324..70028 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
KHW02_RS27205 70093..70176 - 84 Protein_81 hypothetical protein -
KHW02_RS27210 (KHW02_27135) 70292..70480 + 189 WP_000957857.1 hypothetical protein -
KHW02_RS27215 (KHW02_27140) 70490..71689 + 1200 WP_000948429.1 IS91 family transposase ISSbo1 Transposase
KHW02_RS27220 (KHW02_27145) 71856..71999 - 144 Protein_84 AAA family ATPase -
KHW02_RS27225 (KHW02_27150) 72073..72489 - 417 WP_001044770.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
KHW02_RS27230 (KHW02_27155) 72486..72716 - 231 WP_001261282.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
KHW02_RS27235 (KHW02_27160) 72673..73133 + 461 Protein_87 hypothetical protein -
KHW02_RS27240 (KHW02_27165) 73261..73581 + 321 WP_032072060.1 hypothetical protein -
KHW02_RS27245 (KHW02_27170) 73790..73978 + 189 WP_000957857.1 hypothetical protein -
KHW02_RS27250 (KHW02_27175) 73988..75187 + 1200 WP_000948429.1 IS91 family transposase ISSbo1 Transposase
KHW02_RS27255 (KHW02_27180) 75360..75482 + 123 Protein_91 phage integrase family protein -
KHW02_RS27260 (KHW02_27185) 75540..75797 - 258 WP_032408936.1 hypothetical protein -
KHW02_RS27265 (KHW02_27190) 75926..76039 - 114 WP_032072094.1 hypothetical protein -
KHW02_RS27270 (KHW02_27195) 76670..77425 + 756 WP_012539983.1 replication initiation protein RepE -
KHW02_RS27275 (KHW02_27200) 77513..79051 - 1539 WP_022644883.1 IS66 family transposase ISKpn24 Transposase
KHW02_RS27280 (KHW02_27205) 79100..79447 - 348 WP_000612626.1 IS66 family transposase ISKpn24 Transposase
KHW02_RS27285 (KHW02_27210) 79444..79848 - 405 WP_007372134.1 IS66 family transposase ISKpn24 Transposase
KHW02_RS27290 (KHW02_27215) 80630..81835 + 1206 WP_015632469.1 AAA family ATPase -
KHW02_RS27295 (KHW02_27220) 81835..82809 + 975 WP_022644882.1 ParB family protein -
KHW02_RS27300 (KHW02_27225) 82891..84162 - 1272 WP_022644881.1 Y-family DNA polymerase -
KHW02_RS27305 (KHW02_27230) 84162..84593 - 432 WP_020805749.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
KHW02_RS27310 (KHW02_27235) 84826..85797 + 972 WP_001568038.1 plasmid segregation protein ParM -
KHW02_RS27315 (KHW02_27240) 85800..86471 + 672 WP_022644880.1 plasmid partitioning/stability family protein -
KHW02_RS27320 (KHW02_27245) 86533..86763 + 231 WP_001568040.1 hypothetical protein -
KHW02_RS27325 86959..87128 + 170 Protein_105 hypothetical protein -
KHW02_RS27330 (KHW02_27250) 87200..87901 + 702 WP_004152355.1 DNA methylase -
KHW02_RS27335 (KHW02_27255) 87901..88122 + 222 WP_001568042.1 hypothetical protein -
KHW02_RS27340 (KHW02_27260) 88132..88551 + 420 WP_022644879.1 DUF1380 family protein -
KHW02_RS27345 (KHW02_27265) 88605..89372 + 768 WP_022644878.1 hypothetical protein -
KHW02_RS27350 (KHW02_27270) 90053..90481 + 429 WP_022644877.1 antirestriction protein -
KHW02_RS27355 (KHW02_27275) 90524..91030 + 507 WP_048293767.1 antirestriction protein ArdA -
KHW02_RS27360 (KHW02_27280) 91073..91264 + 192 WP_001568047.1 hypothetical protein -
KHW02_RS27365 (KHW02_27285) 91452..91715 + 264 WP_022644876.1 DNA polymerase III subunit theta -
KHW02_RS27370 (KHW02_27290) 91740..92060 + 321 WP_022644875.1 hypothetical protein -
KHW02_RS27375 92438..92535 - 98 Protein_115 hypothetical protein -
KHW02_RS27380 (KHW02_27295) 92819..93376 + 558 WP_020314935.1 single-stranded DNA-binding protein -
KHW02_RS27385 (KHW02_27300) 93426..93674 + 249 WP_020314938.1 DUF905 domain-containing protein -
KHW02_RS27390 (KHW02_27305) 93743..95743 + 2001 WP_020314932.1 ParB/RepB/Spo0J family partition protein -
KHW02_RS27395 (KHW02_27310) 95784..96218 + 435 WP_086556807.1 conjugation system SOS inhibitor PsiB -
KHW02_RS27400 (KHW02_27315) 96215..96943 + 729 WP_020314934.1 plasmid SOS inhibition protein A -
KHW02_RS27405 (KHW02_27320) 96940..97263 + 324 WP_020314937.1 hypothetical protein -
KHW02_RS27410 97653..97749 - 97 Protein_122 hypothetical protein -
KHW02_RS27415 (KHW02_27325) 98079..98306 + 228 WP_022644716.1 hypothetical protein -
KHW02_RS27420 (KHW02_27330) 98401..98631 + 231 WP_020321344.1 hypothetical protein -
KHW02_RS27425 (KHW02_27335) 98680..99555 + 876 WP_022644715.1 DUF4942 domain-containing protein -
KHW02_RS27430 (KHW02_27340) 100338..100676 + 339 WP_022644945.1 hypothetical protein -
KHW02_RS27435 (KHW02_27345) 100732..101079 + 348 WP_022644944.1 hypothetical protein -
KHW02_RS27440 (KHW02_27350) 101172..101318 + 147 WP_022644943.1 hypothetical protein -
KHW02_RS27445 101366..101602 + 237 Protein_129 SAM-dependent DNA methyltransferase -
KHW02_RS27450 (KHW02_27360) 101951..102493 + 543 WP_022644941.1 antirestriction protein -
KHW02_RS27455 (KHW02_27365) 102517..102939 - 423 WP_072205880.1 hypothetical protein VF
KHW02_RS27460 (KHW02_27370) 103445..103837 + 393 WP_022644939.1 conjugal transfer relaxosome DNA-binding protein TraM -
KHW02_RS27465 (KHW02_27375) 104072..104773 + 702 WP_022644938.1 hypothetical protein -
KHW02_RS27470 (KHW02_27380) 104858..105058 + 201 WP_032072063.1 TraY domain-containing protein -
KHW02_RS27475 (KHW02_27385) 105127..105495 + 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
KHW02_RS27480 (KHW02_27390) 105509..105814 + 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
KHW02_RS27485 (KHW02_27395) 105834..106400 + 567 WP_004144423.1 type IV conjugative transfer system protein TraE -
KHW02_RS27490 (KHW02_27400) 106387..107127 + 741 WP_004152497.1 type-F conjugative transfer system secretin TraK -
KHW02_RS27495 (KHW02_27405) 107127..108551 + 1425 WP_022644937.1 F-type conjugal transfer pilus assembly protein TraB -
KHW02_RS27500 (KHW02_27410) 108665..109249 + 585 WP_004161368.1 type IV conjugative transfer system lipoprotein TraV -
KHW02_RS27505 (KHW02_27415) 109381..109791 + 411 WP_004152499.1 hypothetical protein -
KHW02_RS27510 (KHW02_27420) 109897..110115 + 219 WP_004152501.1 hypothetical protein -
KHW02_RS27515 (KHW02_27425) 110116..110427 + 312 WP_004152502.1 hypothetical protein -
KHW02_RS27520 (KHW02_27430) 110494..110898 + 405 WP_004152503.1 hypothetical protein -
KHW02_RS27525 (KHW02_27435) 110941..111330 + 390 WP_004153076.1 hypothetical protein -
KHW02_RS27530 (KHW02_27440) 111338..111736 + 399 WP_011977783.1 hypothetical protein -
KHW02_RS27535 (KHW02_27445) 111808..114447 + 2640 WP_022644936.1 type IV secretion system protein TraC -
KHW02_RS27540 (KHW02_27450) 114447..114839 + 393 WP_022644935.1 type-F conjugative transfer system protein TrbI -
KHW02_RS27545 (KHW02_27455) 114836..115471 + 636 WP_020325113.1 type-F conjugative transfer system protein TraW -
KHW02_RS27550 (KHW02_27460) 115506..115907 + 402 WP_022644934.1 hypothetical protein -
KHW02_RS27555 (KHW02_27465) 115904..116893 + 990 WP_015632509.1 conjugal transfer pilus assembly protein TraU -
KHW02_RS27560 (KHW02_27470) 116906..117544 + 639 WP_022644933.1 type-F conjugative transfer system pilin assembly protein TrbC -
KHW02_RS27565 (KHW02_27475) 117603..119558 + 1956 WP_022644932.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
KHW02_RS27570 (KHW02_27480) 119590..119844 + 255 WP_004152674.1 conjugal transfer protein TrbE -
KHW02_RS27575 (KHW02_27485) 119822..120070 + 249 WP_022644931.1 hypothetical protein -
KHW02_RS27580 (KHW02_27490) 120083..120409 + 327 WP_004152676.1 hypothetical protein -
KHW02_RS27585 (KHW02_27495) 120430..121182 + 753 WP_004152677.1 type-F conjugative transfer system pilin assembly protein TraF -
KHW02_RS27590 (KHW02_27500) 121193..121432 + 240 WP_004144400.1 type-F conjugative transfer system pilin chaperone TraQ -
KHW02_RS27595 (KHW02_27505) 121404..121961 + 558 WP_022644930.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
KHW02_RS27600 (KHW02_27510) 122007..122450 + 444 WP_004194305.1 F-type conjugal transfer protein TrbF -
KHW02_RS27605 (KHW02_27515) 122428..123807 + 1380 WP_073546760.1 conjugal transfer pilus assembly protein TraH -
KHW02_RS27610 (KHW02_27520) 123807..126656 + 2850 WP_004152624.1 conjugal transfer mating-pair stabilization protein TraG -
KHW02_RS27615 (KHW02_27525) 126669..127217 + 549 WP_004152623.1 conjugal transfer entry exclusion protein TraS -
KHW02_RS27620 (KHW02_27530) 127401..128132 + 732 WP_004152622.1 conjugal transfer complement resistance protein TraT -
KHW02_RS27625 (KHW02_27535) 128324..129013 + 690 WP_022644928.1 hypothetical protein -
KHW02_RS27630 (KHW02_27540) 129142..131454 + 2313 WP_032072078.1 type IV conjugative transfer system coupling protein TraD -
KHW02_RS27635 (KHW02_27545) 131454..136715 + 5262 WP_022644926.1 Multifunctional conjugation protein TraI Relaxase
KHW02_RS27640 (KHW02_27550) 136796..137521 + 726 WP_032072081.1 type-F conjugative transfer system pilin acetylase TraX -
KHW02_RS27645 (KHW02_27555) 137678..138271 + 594 WP_022644924.1 fertility inhibition protein FinO -
KHW02_RS27650 (KHW02_27560) 138432..139034 + 603 WP_072216873.1 PIN domain-containing protein -
KHW02_RS27655 (KHW02_27565) 139084..139707 + 624 WP_022644923.1 hypothetical protein -
KHW02_RS27660 (KHW02_27570) 139713..140363 + 651 WP_022644922.1 DUF2726 domain-containing protein -
KHW02_RS27665 140360..140668 + 309 WP_022644921.1 hypothetical protein -
KHW02_RS27670 (KHW02_27575) 140766..141323 + 558 WP_022644920.1 Phospholipase D VF
KHW02_RS27675 (KHW02_27580) 141455..141712 + 258 WP_022644919.1 replication regulatory protein RepA -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance