MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 115320 bp
Accession: NZ_CP074543 Location: 1..115320 Organism: Klebsiella pneumoniae strain S24_CRE24 Replicon: plasmid pCRE24_2
Accession: NZ_CP074543 Location: 1..115320 Organism: Klebsiella pneumoniae strain S24_CRE24 Replicon: plasmid pCRE24_2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KHV99_RS28415 (KHV99_28320) | 1..780 | + | 780 | WP_004152394.1 | IS21 family transposase ISKpn7 | Transposase |
| KHV99_RS28420 (KHV99_28325) | 1099..1980 | + | 882 | WP_004152396.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| KHV99_RS28425 (KHV99_28330) | 2230..3549 | - | 1320 | WP_004152397.1 | IS1182 family transposase ISKpn6 | Transposase |
| KHV99_RS28430 | 3731..4114 | - | 384 | WP_022644889.1 | hypothetical protein | - |
| KHV99_RS28435 (KHV99_28340) | 4144..4336 | + | 193 | Protein_5 | MFS transporter | - |
| KHV99_RS28440 (KHV99_28345) | 4461..4832 | + | 372 | WP_004196359.1 | hypothetical protein | - |
| KHV99_RS28445 (KHV99_28350) | 4895..5815 | + | 921 | WP_004196315.1 | hypothetical protein | - |
| KHV99_RS28450 (KHV99_28355) | 5869..6627 | + | 759 | WP_004196325.1 | hypothetical protein | - |
| KHV99_RS28455 (KHV99_28360) | 6861..8159 | + | 1299 | WP_004196314.1 | MFS transporter | - |
| KHV99_RS28460 (KHV99_28365) | 8265..8534 | + | 270 | WP_004196355.1 | nickel-sensing transcriptional repressor NcrB | - |
| KHV99_RS28465 (KHV99_28370) | 8547..9677 | + | 1131 | WP_004196366.1 | Ni(II)/Co(II) efflux transporter permease subunit NcrC | - |
| KHV99_RS28470 (KHV99_28375) | 9839..10261 | + | 423 | WP_032072095.1 | nickel resistance OB fold protein NcrY | - |
| KHV99_RS28475 (KHV99_28380) | 10517..11857 | - | 1341 | WP_004196353.1 | ISNCY family transposase ISCARN112 | Transposase |
| KHV99_RS28480 (KHV99_28385) | 11946..13478 | + | 1533 | WP_015065592.1 | IS3 family transposase ISKpn38 | Transposase |
| KHV99_RS28485 (KHV99_28390) | 13912..16422 | - | 2511 | WP_022644890.1 | S8 family peptidase | - |
| KHV99_RS28490 (KHV99_28395) | 16400..17440 | - | 1041 | WP_022644891.1 | ATP-binding protein | - |
| KHV99_RS28500 (KHV99_28405) | 19174..19500 | - | 327 | WP_015632484.1 | hypothetical protein | - |
| KHV99_RS28505 (KHV99_28410) | 19497..20225 | - | 729 | WP_022644893.1 | plasmid SOS inhibition protein A | - |
| KHV99_RS28510 (KHV99_28415) | 20222..20653 | - | 432 | WP_015632482.1 | conjugation system SOS inhibitor PsiB | - |
| KHV99_RS28515 (KHV99_28420) | 20698..22698 | - | 2001 | WP_022644894.1 | ParB/RepB/Spo0J family partition protein | - |
| KHV99_RS28520 (KHV99_28425) | 22767..23015 | - | 249 | WP_022644895.1 | DUF905 domain-containing protein | - |
| KHV99_RS28525 (KHV99_28430) | 23064..23606 | - | 543 | WP_022644896.1 | single-stranded DNA-binding protein | - |
| KHV99_RS28530 (KHV99_28435) | 24281..24601 | - | 321 | WP_022644897.1 | hypothetical protein | - |
| KHV99_RS28535 (KHV99_28440) | 24637..24891 | - | 255 | WP_032409268.1 | DNA polymerase III subunit theta | - |
| KHV99_RS28540 (KHV99_28445) | 25079..25270 | - | 192 | WP_001568047.1 | hypothetical protein | - |
| KHV99_RS28545 (KHV99_28450) | 25313..25819 | - | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| KHV99_RS28550 (KHV99_28455) | 25862..26290 | - | 429 | WP_022644877.1 | antirestriction protein | - |
| KHV99_RS28555 (KHV99_28460) | 26971..27738 | - | 768 | WP_022644878.1 | hypothetical protein | - |
| KHV99_RS28560 (KHV99_28465) | 27792..28211 | - | 420 | WP_022644879.1 | DUF1380 family protein | - |
| KHV99_RS28565 (KHV99_28470) | 28221..28442 | - | 222 | WP_001568042.1 | hypothetical protein | - |
| KHV99_RS28570 (KHV99_28475) | 28442..29143 | - | 702 | WP_004152355.1 | DNA methylase | - |
| KHV99_RS28575 | 29215..29384 | - | 170 | Protein_33 | hypothetical protein | - |
| KHV99_RS28580 (KHV99_28480) | 29580..29810 | - | 231 | WP_001568040.1 | hypothetical protein | - |
| KHV99_RS28585 (KHV99_28485) | 29872..30543 | - | 672 | WP_022644880.1 | plasmid partitioning/stability family protein | - |
| KHV99_RS28590 (KHV99_28490) | 30546..31517 | - | 972 | WP_001568038.1 | plasmid segregation protein ParM | - |
| KHV99_RS28595 (KHV99_28495) | 31750..32181 | + | 432 | WP_020805749.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| KHV99_RS28600 (KHV99_28500) | 32181..33452 | + | 1272 | WP_022644881.1 | Y-family DNA polymerase | - |
| KHV99_RS28605 (KHV99_28505) | 33534..34508 | - | 975 | WP_022644882.1 | ParB family protein | - |
| KHV99_RS28610 (KHV99_28510) | 34508..35713 | - | 1206 | WP_015632469.1 | AAA family ATPase | - |
| KHV99_RS28615 (KHV99_28515) | 36495..36899 | + | 405 | WP_007372134.1 | IS66 family transposase ISKpn24 | Transposase |
| KHV99_RS28620 (KHV99_28520) | 36896..37243 | + | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| KHV99_RS28625 (KHV99_28525) | 37292..38830 | + | 1539 | WP_022644883.1 | IS66 family transposase ISKpn24 | Transposase |
| KHV99_RS28630 (KHV99_28530) | 38918..39673 | - | 756 | WP_012539983.1 | replication initiation protein RepE | - |
| KHV99_RS28635 (KHV99_28535) | 40304..40417 | + | 114 | WP_032072094.1 | hypothetical protein | - |
| KHV99_RS28640 (KHV99_28540) | 40546..40803 | + | 258 | WP_032408936.1 | hypothetical protein | - |
| KHV99_RS28645 (KHV99_28545) | 40861..41646 | - | 786 | WP_022644886.1 | site-specific integrase | - |
| KHV99_RS28650 (KHV99_28550) | 41649..42287 | - | 639 | WP_022644887.1 | hypothetical protein | - |
| KHV99_RS28655 (KHV99_28555) | 42336..42656 | - | 321 | WP_032072060.1 | hypothetical protein | - |
| KHV99_RS28660 (KHV99_28560) | 42784..43244 | - | 461 | Protein_50 | hypothetical protein | - |
| KHV99_RS28665 (KHV99_28565) | 43201..43431 | + | 231 | WP_001261282.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| KHV99_RS28670 (KHV99_28570) | 43428..43844 | + | 417 | WP_001044770.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| KHV99_RS28675 (KHV99_28575) | 43918..44136 | + | 219 | Protein_53 | AAA family ATPase | - |
| KHV99_RS28680 (KHV99_28580) | 44201..44905 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KHV99_RS28685 | 44939..45295 | - | 357 | WP_004199403.1 | hypothetical protein | - |
| KHV99_RS28690 (KHV99_28585) | 45298..45537 | - | 240 | WP_001549892.1 | hypothetical protein | - |
| KHV99_RS28695 (KHV99_28590) | 45624..46286 | - | 663 | WP_001549893.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| KHV99_RS28700 (KHV99_28595) | 46667..47329 | + | 663 | WP_000516402.1 | division plane positioning ATPase MipZ | - |
| KHV99_RS28705 (KHV99_28600) | 47429..47713 | + | 285 | WP_001185481.1 | hypothetical protein | - |
| KHV99_RS28710 (KHV99_28605) | 47919..48230 | + | 312 | WP_000469598.1 | hypothetical protein | - |
| KHV99_RS28715 (KHV99_28610) | 48266..48550 | + | 285 | WP_001043731.1 | hypothetical protein | - |
| KHV99_RS28720 (KHV99_28615) | 48571..48924 | - | 354 | WP_000877224.1 | DNA distortion polypeptide 3 | - |
| KHV99_RS28725 (KHV99_28620) | 49112..49555 | - | 444 | WP_001074369.1 | hypothetical protein | - |
| KHV99_RS28730 (KHV99_28625) | 49564..50577 | - | 1014 | WP_001348704.1 | replication initiation protein | - |
| KHV99_RS28735 (KHV99_28630) | 51188..51340 | + | 153 | Protein_65 | DNA-binding protein | - |
| KHV99_RS28740 (KHV99_28635) | 51930..52445 | + | 516 | WP_001025390.1 | DnaJ domain-containing protein | - |
| KHV99_RS28745 (KHV99_28640) | 52504..52740 | + | 237 | WP_000792381.1 | hypothetical protein | - |
| KHV99_RS28750 (KHV99_28645) | 52800..53351 | + | 552 | WP_000662998.1 | hypothetical protein | - |
| KHV99_RS28755 (KHV99_28650) | 53360..53629 | + | 270 | WP_001006717.1 | hypothetical protein | - |
| KHV99_RS28760 (KHV99_28655) | 53619..53861 | + | 243 | WP_000008707.1 | hypothetical protein | - |
| KHV99_RS28765 (KHV99_28660) | 53955..54293 | + | 339 | WP_001099725.1 | hypothetical protein | - |
| KHV99_RS28770 (KHV99_28665) | 54368..54532 | + | 165 | WP_000004083.1 | hypothetical protein | - |
| KHV99_RS28775 (KHV99_28670) | 54529..54786 | + | 258 | WP_004199355.1 | hypothetical protein | - |
| KHV99_RS28780 (KHV99_28680) | 55127..55672 | + | 546 | WP_001348698.1 | DNA distortion polypeptide 1 | - |
| KHV99_RS28785 (KHV99_28685) | 55675..56835 | + | 1161 | WP_004199101.1 | hypothetical protein | Relaxase |
| KHV99_RS28790 (KHV99_28690) | 57188..57697 | + | 510 | WP_000455437.1 | transcription termination/antitermination NusG family protein | - |
| KHV99_RS28795 (KHV99_28695) | 57648..57884 | + | 237 | WP_001348696.1 | hypothetical protein | - |
| KHV99_RS28800 (KHV99_28700) | 57930..58574 | + | 645 | WP_000953538.1 | Type IV secretion system protein virB1 | VF |
| KHV99_RS28805 (KHV99_28705) | 58558..58848 | + | 291 | WP_000916156.1 | TrbC/VirB2 family protein | - |
| KHV99_RS28810 (KHV99_28710) | 58873..61626 | + | 2754 | WP_000108726.1 | Type IV secretion system protein virB4 | VF |
| KHV99_RS28815 (KHV99_28715) | 61636..62406 | + | 771 | WP_000716326.1 | type IV secretion system protein | - |
| KHV99_RS28820 (KHV99_28720) | 62416..62673 | + | 258 | WP_000759841.1 | EexN family lipoprotein | - |
| KHV99_RS28825 (KHV99_28725) | 62685..63740 | + | 1056 | WP_000235886.1 | hypothetical protein | VF |
| KHV99_RS28830 (KHV99_28730) | 63935..64662 | + | 728 | Protein_84 | Type IV secretion system protein PtlE | VF |
| KHV99_RS28835 (KHV99_28735) | 64668..65597 | + | 930 | WP_000783386.1 | TrbG/VirB9 family P-type conjugative transfer protein | - |
| KHV99_RS28840 (KHV99_28740) | 65594..66808 | + | 1215 | WP_001295060.1 | Type IV secretion system protein virB10 | VF |
| KHV99_RS28845 (KHV99_28745) | 66810..67007 | + | 198 | WP_000629109.1 | DNA-binding protein | - |
| KHV99_RS28850 (KHV99_28750) | 67004..68038 | + | 1035 | WP_000650512.1 | Type IV secretion system protein PtlH | VF |
| KHV99_RS28855 (KHV99_28755) | 68041..69876 | + | 1836 | WP_000053822.1 | type IV secretory system conjugative DNA transfer family protein | - |
| KHV99_RS28860 (KHV99_28760) | 69873..70265 | + | 393 | WP_000738524.1 | cag pathogenicity island Cag12 family protein | - |
| KHV99_RS28865 (KHV99_28765) | 70353..70667 | + | 315 | WP_000754496.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| KHV99_RS28870 (KHV99_28770) | 70753..71079 | + | 327 | WP_004208538.1 | hypothetical protein | - |
| KHV99_RS28875 (KHV99_28775) | 71076..71570 | + | 495 | WP_001215543.1 | thermonuclease family protein | - |
| KHV99_RS28880 (KHV99_28780) | 71653..72915 | + | 1263 | WP_000517490.1 | ATP-binding protein | - |
| KHV99_RS28885 (KHV99_28785) | 72919..75246 | + | 2328 | WP_004199098.1 | type IA DNA topoisomerase | - |
| KHV99_RS28890 (KHV99_28790) | 75258..75713 | + | 456 | WP_001293458.1 | H-NS family nucleoid-associated regulatory protein | - |
| KHV99_RS28895 (KHV99_28795) | 75751..76401 | - | 651 | WP_000351937.1 | YkgJ family cysteine cluster protein | - |
| KHV99_RS28900 (KHV99_28800) | 76391..76657 | + | 267 | WP_032072053.1 | hypothetical protein | - |
| KHV99_RS28905 (KHV99_28805) | 76674..76853 | + | 180 | WP_000136657.1 | hypothetical protein | - |
| KHV99_RS28910 (KHV99_28810) | 76850..77671 | + | 822 | WP_000196235.1 | SprT-like domain-containing protein | - |
| KHV99_RS28915 (KHV99_28815) | 77781..78035 | + | 255 | WP_000510385.1 | hypothetical protein | - |
| KHV99_RS28920 (KHV99_28820) | 78053..78328 | + | 276 | WP_000557557.1 | hypothetical protein | - |
| KHV99_RS28925 (KHV99_28825) | 78325..78603 | + | 279 | WP_001093608.1 | hypothetical protein | - |
| KHV99_RS28930 (KHV99_28835) | 79722..80267 | - | 546 | Protein_104 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KHV99_RS28935 (KHV99_28840) | 80411..83428 | + | 3018 | WP_004199413.1 | Tn3 family transposase TnpA_IS3000 | Transposase |
| KHV99_RS28940 (KHV99_28845) | 83415..84625 | - | 1211 | Protein_106 | four-carbon acid sugar kinase family protein | - |
| KHV99_RS28945 (KHV99_28850) | 84637..85539 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| KHV99_RS28950 (KHV99_28855) | 85801..86562 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| KHV99_RS28955 (KHV99_28860) | 86583..87443 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| KHV99_RS28960 (KHV99_28865) | 87580..88284 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KHV99_RS28965 (KHV99_28870) | 88337..89104 | - | 768 | Protein_111 | IS91 family transposase ISAzo26 | Transposase |
| KHV99_RS28970 (KHV99_28875) | 89260..89733 | + | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| KHV99_RS28975 | 89954..90070 | + | 117 | Protein_113 | hypothetical protein | Relaxase |
| KHV99_RS28980 | 90180..90245 | + | 66 | Protein_114 | hypothetical protein | Relaxase |
| KHV99_RS28985 (KHV99_28885) | 90363..91127 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| KHV99_RS28990 (KHV99_28890) | 91267..91332 | - | 66 | Protein_116 | EAL domain-containing protein | - |
| KHV99_RS28995 (KHV99_28895) | 91388..92602 | + | 1215 | WP_004098817.1 | type II site-specific deoxyribonuclease | - |
| KHV99_RS29000 (KHV99_28900) | 92636..94069 | - | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| KHV99_RS29005 (KHV99_28905) | 94168..94440 | + | 273 | Protein_119 | IS1 family transposase IS1X2 | Transposase |
| KHV99_RS29010 (KHV99_28910) | 94451..94657 | - | 207 | WP_001749967.1 | hypothetical protein | - |
| KHV99_RS29015 (KHV99_28915) | 94662..95309 | - | 648 | WP_012561184.1 | restriction endonuclease | - |
| KHV99_RS29020 (KHV99_28920) | 95359..95670 | - | 312 | WP_001452736.1 | hypothetical protein | - |
| KHV99_RS29025 (KHV99_28925) | 95706..96056 | - | 351 | WP_032072070.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| KHV99_RS29030 (KHV99_28930) | 96047..96751 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KHV99_RS29035 (KHV99_28935) | 96803..98569 | + | 1767 | Protein_125 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| KHV99_RS29040 (KHV99_28940) | 98648..99652 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| KHV99_RS29045 | 99924..100010 | - | 87 | Protein_127 | Arm DNA-binding domain-containing protein | - |
| KHV99_RS29050 (KHV99_28950) | 100340..101155 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| KHV99_RS29055 (KHV99_28955) | 101216..102019 | + | 804 | WP_072664391.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| KHV99_RS29060 (KHV99_28960) | 102019..102855 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| KHV99_RS29065 (KHV99_28965) | 102962..103366 | - | 405 | Protein_131 | IS91 family transposase ISPps1 | Transposase |
| KHV99_RS29070 (KHV99_28970) | 103576..104436 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| KHV99_RS29075 (KHV99_28975) | 104619..104936 | - | 318 | Protein_133 | Tn3 family transposase TnpR_Tn3 | Transposase |
| KHV99_RS29080 (KHV99_28980) | 105136..105960 | - | 825 | WP_000722315.1 | Beta-lactamase OXA-18 | ARG |
| KHV99_RS29085 (KHV99_28985) | 106020..106808 | - | 789 | WP_001206315.1 | Streptomycin 3''-adenylyltransferase | ARG |
| KHV99_RS29090 (KHV99_28990) | 106878..107432 | - | 555 | WP_063840280.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| KHV99_RS29095 (KHV99_28995) | 107666..108223 | - | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| KHV99_RS29100 (KHV99_29000) | 108387..109286 | + | 900 | Protein_138 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KHV99_RS29105 (KHV99_29005) | 109338..111053 | - | 1716 | WP_004152391.1 | Tn3-like element Tn4401 family resolvase TnpR | - |
| KHV99_RS29110 (KHV99_29010) | 111163..114192 | + | 3030 | WP_004152392.1 | Tn3 family transposase ISPsy42 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|