MGE detailed information
MGE type: Conjugative plasmid MGE length: 94462 bp
Accession: NZ_CP072981 Location: 1..94462 Organism: Escherichia coli strain 2547 Replicon: plasmid pEC2547-KPC-2
Accession: NZ_CP072981 Location: 1..94462 Organism: Escherichia coli strain 2547 Replicon: plasmid pEC2547-KPC-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KBW66_RS25310 (KBW66_25310) | 1090..1971 | + | 882 | WP_004199234.1 | hypothetical protein | ARG |
| KBW66_RS25315 (KBW66_25315) | 2221..2613 | - | 393 | Protein_2 | IS1182 family transposase ISKpn6 | Transposase |
| KBW66_RS25320 (KBW66_25320) | 2663..3367 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| KBW66_RS25325 (KBW66_25325) | 3433..4914 | + | 1482 | Protein_4 | Tn3 family transposase TnpA_Tn3 | Transposase |
| KBW66_RS25330 (KBW66_25330) | 5218..5670 | - | 453 | WP_001749986.1 | hypothetical protein | ARG |
| KBW66_RS25335 (KBW66_25335) | 5767..6321 | - | 555 | WP_032488579.1 | hypothetical protein | ARG |
| KBW66_RS25340 (KBW66_25340) | 6613..7626 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| KBW66_RS25345 (KBW66_25345) | 7974..8540 | - | 567 | WP_003159185.1 | Tn3 family transposase ISPsy42 | Transposase |
| KBW66_RS25350 (KBW66_25350) | 8669..8917 | - | 249 | WP_011191340.1 | type II toxin-antitoxin system YafQ family toxin | - |
| KBW66_RS25355 (KBW66_25355) | 9572..9868 | + | 297 | WP_012477889.1 | HigA family addiction module antitoxin | - |
| KBW66_RS25360 (KBW66_25360) | 10041..10655 | + | 615 | Protein_11 | replication protein | - |
| KBW66_RS25365 (KBW66_25365) | 10719..11423 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KBW66_RS25370 (KBW66_25370) | 11477..12108 | - | 632 | Protein_13 | transposase | - |
| KBW66_RS25375 (KBW66_25375) | 12503..13159 | + | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| KBW66_RS25380 (KBW66_25380) | 13478..14092 | - | 615 | WP_014839983.1 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| KBW66_RS25385 (KBW66_25385) | 14254..14436 | + | 183 | Protein_16 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| KBW66_RS25390 (KBW66_25390) | 14572..15117 | + | 546 | WP_001493763.1 | plasmid pRiA4b ORF-3 family protein | - |
| KBW66_RS25395 (KBW66_25395) | 15254..15826 | + | 573 | WP_001493762.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| KBW66_RS25400 (KBW66_25400) | 15863..17137 | + | 1275 | Protein_19 | ISKra4 family transposase ISKpn19 | Transposase |
| KBW66_RS25405 (KBW66_25405) | 17191..17888 | + | 698 | WP_095033700.1 | IS1-like element IS1B family transposase | - |
| KBW66_RS25410 (KBW66_25410) | 18288..18416 | + | 129 | WP_002210551.1 | hypothetical protein | - |
| KBW66_RS25415 (KBW66_25415) | 18590..19123 | - | 534 | WP_000792636.1 | Cardiolipin synthase A | VF |
| KBW66_RS25420 (KBW66_25420) | 19123..20118 | - | 996 | WP_000128596.1 | hypothetical protein | VF |
| KBW66_RS25425 (KBW66_25425) | 20160..21320 | - | 1161 | WP_000101710.1 | Chromosome-partitioning ATPase Soj | VF |
| KBW66_RS25430 (KBW66_25430) | 21320..22204 | - | 885 | WP_000735066.1 | Transcriptional repressor protein KorB | VF |
| KBW66_RS25435 (KBW66_25435) | 22215..22913 | - | 699 | WP_000646594.1 | hypothetical protein | VF |
| KBW66_RS25440 (KBW66_25440) | 22903..23049 | - | 147 | WP_001257173.1 | conjugal transfer protein TraN | - |
| KBW66_RS25445 (KBW66_25445) | 23132..24172 | - | 1041 | WP_001749958.1 | type IV secretion system protein | - |
| KBW66_RS25450 (KBW66_25450) | 24188..24415 | - | 228 | WP_001749959.1 | IncN-type entry exclusion lipoprotein EexN | - |
| KBW66_RS25455 (KBW66_25455) | 24423..25136 | - | 714 | WP_001749960.1 | TelA-like protein | VF |
| KBW66_RS25460 (KBW66_25460) | 25154..27754 | - | 2601 | WP_001749961.1 | hypothetical protein | VF |
| KBW66_RS25465 (KBW66_25465) | 27754..28071 | - | 318 | WP_000496058.1 | hypothetical protein | VF |
| KBW66_RS25470 (KBW66_25470) | 28121..28414 | - | 294 | WP_001749962.1 | hypothetical protein | - |
| KBW66_RS25475 (KBW66_25475) | 28424..28705 | - | 282 | WP_000440698.1 | transcriptional repressor KorA | - |
| KBW66_RS25480 (KBW66_25480) | 28714..29448 | - | 735 | WP_001749963.1 | hypothetical protein | VF |
| KBW66_RS25485 (KBW66_25485) | 29557..29862 | + | 306 | WP_000960954.1 | H-NS family nucleoid-associated regulatory protein | - |
| KBW66_RS25490 (KBW66_25490) | 29878..30222 | + | 345 | WP_001749964.1 | hypothetical protein | - |
| KBW66_RS25495 (KBW66_25495) | 30219..30533 | + | 315 | WP_001749965.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| KBW66_RS25500 (KBW66_25500) | 30569..30880 | + | 312 | WP_001452736.1 | hypothetical protein | - |
| KBW66_RS25505 (KBW66_25505) | 30930..31577 | + | 648 | WP_015344958.1 | restriction endonuclease | - |
| KBW66_RS25510 (KBW66_25510) | 31582..31788 | + | 207 | WP_001749967.1 | hypothetical protein | - |
| KBW66_RS25515 (KBW66_25515) | 31799..32071 | - | 273 | Protein_42 | IS1 family transposase | - |
| KBW66_RS25520 (KBW66_25520) | 32170..33603 | + | 1434 | WP_001288432.1 | DNA cytosine methyltransferase | - |
| KBW66_RS25525 (KBW66_25525) | 33637..34851 | - | 1215 | WP_004098817.1 | type II site-specific deoxyribonuclease | - |
| KBW66_RS25530 (KBW66_25530) | 34907..34972 | + | 66 | Protein_45 | EAL domain-containing protein | - |
| KBW66_RS25535 (KBW66_25535) | 35112..35876 | - | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| KBW66_RS26815 | 35994..36059 | - | 66 | Protein_47 | EAL domain-containing protein | - |
| KBW66_RS26820 | 36169..36285 | - | 117 | Protein_48 | plasmid mobilization relaxosome protein MobC | - |
| KBW66_RS25545 (KBW66_25545) | 36506..36979 | - | 474 | WP_004201280.1 | hypothetical protein | ARG |
| KBW66_RS25550 (KBW66_25550) | 37135..37833 | + | 699 | Protein_50 | IS91 family transposase ISAzo26 | Transposase |
| KBW66_RS25555 (KBW66_25555) | 37898..38602 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| KBW66_RS25560 (KBW66_25560) | 38883..39440 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| KBW66_RS25565 (KBW66_25565) | 39623..40483 | + | 861 | WP_000027057.1 | hypothetical protein | ARG |
| KBW66_RS25570 (KBW66_25570) | 40742..41218 | + | 477 | WP_013023839.1 | WbuC family cupin fold metalloprotein | - |
| KBW66_RS25575 (KBW66_25575) | 41265..42140 | - | 876 | WP_011091028.1 | hypothetical protein | ARG |
| KBW66_RS25580 (KBW66_25580) | 42475..43737 | - | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| KBW66_RS25585 (KBW66_25585) | 44054..44257 | + | 204 | Protein_57 | Tn3 family transposase | - |
| KBW66_RS25590 (KBW66_25590) | 44267..44632 | - | 366 | WP_012561167.1 | hypothetical protein | - |
| KBW66_RS25595 (KBW66_25595) | 44632..47208 | - | 2577 | WP_248860646.1 | Multifunctional conjugation protein TraI | Relaxase |
| KBW66_RS26825 | 47219..47374 | - | 156 | WP_251365047.1 | hypothetical protein | Relaxase |
| KBW66_RS26830 | 47397..47807 | - | 411 | WP_251365041.1 | hypothetical protein | Relaxase |
| KBW66_RS26835 | 48098..48367 | - | 270 | WP_251365042.1 | type IV secretory system conjugative DNA transfer family protein | - |
| KBW66_RS26840 | 48428..48598 | - | 171 | WP_251365048.1 | type IV secretion system DNA-binding domain-containing protein | - |
| KBW66_RS26845 | 48570..48755 | - | 186 | WP_251365043.1 | hypothetical protein | - |
| KBW66_RS26850 | 48799..49395 | - | 597 | WP_251365044.1 | type IV secretion system DNA-binding domain-containing protein | - |
| KBW66_RS26855 | 49440..49688 | - | 249 | WP_251365045.1 | traK protein | - |
| KBW66_RS26860 | 50316..50735 | + | 420 | WP_001749974.1 | plasmid stabilization protein StbA | - |
| KBW66_RS25615 (KBW66_25615) | 50744..51460 | + | 717 | WP_001749973.1 | StbB family protein | - |
| KBW66_RS25620 (KBW66_25620) | 51462..51830 | + | 369 | WP_000414913.1 | plasmid stabilization protein StbC | - |
| KBW66_RS25625 (KBW66_25625) | 52012..52356 | + | 345 | WP_000999874.1 | hypothetical protein | - |
| KBW66_RS25630 (KBW66_25630) | 52467..52787 | - | 321 | WP_001749971.1 | protein CcgAII | - |
| KBW66_RS25635 (KBW66_25635) | 52842..53021 | - | 180 | WP_000214483.1 | protein CcgAI | - |
| KBW66_RS25640 (KBW66_25640) | 53748..54257 | - | 510 | WP_000129958.1 | antirestriction protein ArdA | - |
| KBW66_RS25645 (KBW66_25645) | 55610..55942 | - | 333 | WP_012561126.1 | hypothetical protein | - |
| KBW66_RS25650 (KBW66_25650) | 56151..56435 | - | 285 | WP_001750002.1 | protein CcgC | - |
| KBW66_RS25655 (KBW66_25655) | 56504..56863 | - | 360 | WP_001750003.1 | hypothetical protein | - |
| KBW66_RS25660 (KBW66_25660) | 56860..57156 | - | 297 | WP_000545925.1 | protein CcgD | - |
| KBW66_RS25665 (KBW66_25665) | 58042..58281 | - | 240 | WP_000932975.1 | hypothetical protein | - |
| KBW66_RS25670 (KBW66_25670) | 58291..58695 | - | 405 | WP_000881513.1 | antirestriction protein ArdAB regulator ArdR | - |
| KBW66_RS25675 (KBW66_25675) | 58753..59178 | - | 426 | WP_000447669.1 | antirestriction protein ArdB | - |
| KBW66_RS25680 (KBW66_25680) | 59593..60033 | + | 441 | WP_000861760.1 | translesion error-prone DNA polymerase V autoproteolytic subunit MucA | - |
| KBW66_RS25685 (KBW66_25685) | 60021..61286 | + | 1266 | WP_001749980.1 | translesion error-prone DNA polymerase V subunit MucB | - |
| KBW66_RS25690 (KBW66_25690) | 61437..62228 | + | 792 | WP_001452808.1 | SprT-like domain-containing protein | - |
| KBW66_RS25695 (KBW66_25695) | 62243..62584 | - | 342 | WP_000057569.1 | antirestriction protein ArdAB regulator ArdK | - |
| KBW66_RS25700 (KBW66_25700) | 63144..63863 | + | 720 | WP_001749982.1 | replication initiation protein | - |
| KBW66_RS25705 (KBW66_25705) | 65820..66389 | - | 570 | WP_001749988.1 | Tn3 family transposase TnpR_ISPa38 | Transposase |
| KBW66_RS25710 (KBW66_25710) | 66471..67175 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KBW66_RS25715 (KBW66_25715) | 67237..67776 | + | 540 | WP_251365046.1 | Type IV secretion system protein PtlE | VF |
| KBW66_RS25720 (KBW66_25720) | 67776..68681 | + | 906 | WP_094283540.1 | P-type conjugative transfer protein VirB9 | - |
| KBW66_RS25725 (KBW66_25725) | 68723..69973 | + | 1251 | WP_146999495.1 | Type IV secretion system protein virB10 | VF |
| KBW66_RS25730 (KBW66_25730) | 69977..71002 | + | 1026 | WP_044862971.1 | Type IV secretion system protein VirB11 | VF |
| KBW66_RS25735 (KBW66_25735) | 70999..71397 | + | 399 | WP_094283556.1 | cag pathogenicity island Cag12 family protein | - |
| KBW66_RS25740 (KBW66_25740) | 71427..71726 | + | 300 | WP_000716758.1 | TrbM/KikA/MpfK family conjugal transfer protein | - |
| KBW66_RS25745 (KBW66_25745) | 71729..71944 | + | 216 | WP_094283555.1 | hypothetical protein | - |
| KBW66_RS25750 (KBW66_25750) | 71972..72277 | + | 306 | WP_210796719.1 | dpoa decarboxylase | - |
| KBW66_RS25755 (KBW66_25755) | 73087..74814 | + | 1728 | WP_094283553.1 | type IV secretory system conjugative DNA transfer family protein | - |
| KBW66_RS25760 (KBW66_25760) | 74824..75558 | + | 735 | WP_094283552.1 | MobC family replication-relaxation protein | - |
| KBW66_RS25765 (KBW66_25765) | 75562..76041 | + | 480 | WP_094283551.1 | thermonuclease family protein | - |
| KBW66_RS25770 (KBW66_25770) | 76271..76636 | + | 366 | WP_000124098.1 | hypothetical protein | - |
| KBW66_RS25775 (KBW66_25775) | 76636..77823 | + | 1188 | WP_000937614.1 | IS91 family transposase IS91 | Transposase |
| KBW66_RS25780 (KBW66_25780) | 78073..78306 | - | 234 | WP_000024515.1 | hypothetical protein | - |
| KBW66_RS25785 (KBW66_25785) | 78346..78993 | - | 648 | WP_000214917.1 | ParA family protein | - |
| KBW66_RS25790 (KBW66_25790) | 79356..79706 | + | 351 | WP_094283547.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| KBW66_RS25795 (KBW66_25795) | 79708..80007 | + | 300 | WP_094283546.1 | helix-turn-helix transcriptional regulator | Antitoxin Detail |
| KBW66_RS25800 (KBW66_25800) | 80014..80124 | + | 111 | Protein_105 | transcriptional regulator | - |
| KBW66_RS25805 (KBW66_25805) | 80199..80438 | - | 240 | WP_094283545.1 | hypothetical protein | - |
| KBW66_RS25810 (KBW66_25810) | 80428..80685 | - | 258 | WP_024192529.1 | hypothetical protein | - |
| KBW66_RS25815 (KBW66_25815) | 80722..81264 | - | 543 | WP_094283544.1 | hypothetical protein | - |
| KBW66_RS25820 (KBW66_25820) | 81392..81925 | - | 534 | WP_001025389.1 | J domain-containing protein | - |
| KBW66_RS25825 (KBW66_25825) | 82296..82595 | - | 300 | WP_001615573.1 | hypothetical protein | - |
| KBW66_RS25830 (KBW66_25830) | 82669..82941 | - | 273 | WP_094283543.1 | hypothetical protein | - |
| KBW66_RS25835 (KBW66_25835) | 83900..84613 | - | 714 | WP_223228604.1 | RepA family replication protein | - |
| KBW66_RS25840 (KBW66_25840) | 85184..85552 | - | 369 | WP_029397050.1 | helix-turn-helix transcriptional regulator | - |
| KBW66_RS25845 (KBW66_25845) | 85806..86255 | + | 450 | WP_249540331.1 | transcription termination/antitermination NusG family protein | - |
| KBW66_RS25850 (KBW66_25850) | 86332..86544 | + | 213 | WP_001133545.1 | hypothetical protein | - |
| KBW66_RS25855 (KBW66_25855) | 86545..86751 | + | 207 | WP_029397048.1 | hypothetical protein | - |
| KBW66_RS25860 (KBW66_25860) | 86767..87471 | + | 705 | WP_094283541.1 | Type IV secretion system protein virB1 | VF |
| KBW66_RS25865 (KBW66_25865) | 87475..87771 | + | 297 | WP_029397047.1 | Type IV secretion system protein virB2 | VF |
| KBW66_RS25870 (KBW66_25870) | 87784..90528 | + | 2745 | WP_001096401.1 | Type IV secretion system protein virB4 | VF |
| KBW66_RS25875 (KBW66_25875) | 90543..91247 | + | 705 | WP_032173316.1 | type IV secretion system protein | - |
| KBW66_RS25880 (KBW66_25880) | 91259..91486 | + | 228 | WP_000720509.1 | EexN family lipoprotein | - |
| KBW66_RS25885 (KBW66_25885) | 91496..92566 | + | 1071 | WP_024187435.1 | type IV secretion system protein | - |
| KBW66_RS25890 (KBW66_25890) | 92614..92757 | + | 144 | WP_000825481.1 | hypothetical protein | - |
| KBW66_RS25895 (KBW66_25895) | 92750..92893 | + | 144 | Protein_124 | IS6 family transposase IS15 | Transposase |
| KBW66_RS25900 (KBW66_25900) | 92956..93660 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| KBW66_RS25905 (KBW66_25905) | 93712..94173 | + | 462 | Protein_126 | Tn3 family transposase TnpR_Tn3 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|