MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 132892 bp
Accession: NZ_CP072849 Location: 2309421..2442312 Organism: Vibrio cholerae MO10 Replicon: chromosome
Accession: NZ_CP072849 Location: 2309421..2442312 Organism: Vibrio cholerae MO10 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KAF59_RS10430 (KAF59_10430) | 2305227..2305712 | + | 486 | WP_001911251.1 | inosine/xanthosine triphosphatase | - |
| KAF59_RS10435 (KAF59_10435) | 2305790..2306101 | - | 312 | WP_000250616.1 | trp operon repressor | - |
| KAF59_RS10440 (KAF59_10440) | 2306156..2308102 | - | 1947 | WP_000197615.1 | murein transglycosylase | - |
| KAF59_RS10445 (KAF59_10445) | 2308464..2310131 | + | 1668 | WP_000852865.1 | energy-dependent translational throttle protein EttA | - |
| KAF59_RS10450 (KAF59_10450) | 2310302..2310673 | + | 372 | WP_000570783.1 | PilZ domain-containing protein | - |
| KAF59_RS10455 (KAF59_10455) | 2310740..2311867 | - | 1128 | WP_000257629.1 | T-protein | VF |
| KAF59_RS10460 (KAF59_10460) | 2311880..2312953 | - | 1074 | WP_000747937.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| KAF59_RS10465 (KAF59_10465) | 2313195..2314871 | + | 1677 | WP_000364257.1 | Sensor histidine kinase BtsS | VF |
| KAF59_RS10470 (KAF59_10470) | 2314881..2315594 | + | 714 | WP_000947378.1 | Transcriptional regulatory protein BtsR | VF |
| KAF59_RS10475 (KAF59_10475) | 2315621..2316613 | - | 993 | WP_000529115.1 | beta-N-acetylhexosaminidase | - |
| KAF59_RS10480 (KAF59_10480) | 2316719..2317831 | + | 1113 | WP_000840717.1 | anhydro-N-acetylmuramic acid kinase | - |
| KAF59_RS10485 (KAF59_10485) | 2317849..2318772 | + | 924 | WP_000180252.1 | N-acetylmuramic acid 6-phosphate etherase | - |
| KAF59_RS10490 (KAF59_10490) | 2318796..2320592 | - | 1797 | WP_000544193.1 | sodium:proton antiporter | - |
| KAF59_RS10495 (KAF59_10495) | 2320611..2320952 | - | 342 | WP_001883835.1 | DUF2799 domain-containing protein | - |
| KAF59_RS10500 (KAF59_10500) | 2321205..2322689 | + | 1485 | WP_000964317.1 | carbon starvation protein A | - |
| KAF59_RS10505 (KAF59_10505) | 2322826..2323788 | - | 963 | WP_001883831.1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | - |
| KAF59_RS10510 (KAF59_10510) | 2323823..2324257 | - | 435 | WP_001068088.1 | FKBP-type peptidyl-prolyl cis-trans isomerase | - |
| KAF59_RS10515 (KAF59_10515) | 2324420..2324935 | - | 516 | WP_000071968.1 | Lipoprotein signal peptidase | VF |
| KAF59_RS10520 (KAF59_10520) | 2324951..2327800 | - | 2850 | WP_000006088.1 | isoleucine--tRNA ligase | - |
| KAF59_RS10525 (KAF59_10525) | 2327831..2328799 | - | 969 | WP_000420406.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| KAF59_RS10530 (KAF59_10530) | 2328868..2330430 | - | 1563 | WP_001911253.1 | murein biosynthesis integral membrane protein MurJ | - |
| KAF59_RS10535 (KAF59_10535) | 2330688..2330948 | + | 261 | WP_000002742.1 | 30S ribosomal protein S20 | - |
| KAF59_RS10540 (KAF59_10540) | 2331017..2331319 | - | 303 | WP_001053149.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KAF59_RS10545 (KAF59_10545) | 2331542..2332432 | - | 891 | WP_000018876.1 | Transcriptional activator protein NhaR | VF |
| KAF59_RS10550 (KAF59_10550) | 2332827..2333975 | + | 1149 | WP_000609761.1 | Na/Pi cotransporter family protein | - |
| KAF59_RS10555 (KAF59_10555) | 2334068..2334919 | - | 852 | WP_001250353.1 | thymidylate synthase | - |
| KAF59_RS10560 (KAF59_10560) | 2334929..2335744 | - | 816 | WP_001135560.1 | prolipoprotein diacylglyceryl transferase | - |
| KAF59_RS10565 (KAF59_10565) | 2335773..2336567 | - | 795 | WP_001019422.1 | sulfite exporter TauE/SafE family protein | - |
| KAF59_RS10570 (KAF59_10570) | 2336577..2338823 | - | 2247 | WP_000952226.1 | phosphoenolpyruvate--protein phosphotransferase | - |
| KAF59_RS10575 (KAF59_10575) | 2338826..2339344 | - | 519 | WP_001911254.1 | RNA pyrophosphohydrolase | - |
| KAF59_RS10580 (KAF59_10580) | 2339975..2340640 | + | 666 | WP_000801223.1 | DNA mismatch repair endonuclease MutH | - |
| KAF59_RS10585 (KAF59_10585) | 2340857..2341891 | + | 1035 | WP_001200442.1 | NADP(H)-dependent aldo-keto reductase | - |
| KAF59_RS10590 (KAF59_10590) | 2341929..2342180 | - | 252 | WP_001249919.1 | hypothetical protein | - |
| KAF59_RS10595 (KAF59_10595) | 2342758..2344092 | - | 1335 | WP_000107102.1 | Transcriptional regulatory protein ZraR | VF |
| KAF59_RS10600 (KAF59_10600) | 2344366..2345898 | - | 1533 | WP_000128764.1 | lysine--tRNA ligase | - |
| KAF59_RS10610 (KAF59_10610) | 2347197..2348510 | - | 1314 | WP_000815019.1 | branched-chain amino acid transport system II carrier protein | - |
| KAF59_RS10615 (KAF59_10615) | 2348819..2349541 | + | 723 | WP_000856169.1 | tRNA1(Val) (adenine(37)-N6)-methyltransferase | - |
| KAF59_RS10620 (KAF59_10620) | 2349629..2350900 | + | 1272 | WP_000597951.1 | ATP-dependent RNA helicase SrmB | - |
| KAF59_RS10625 (KAF59_10625) | 2351022..2352611 | - | 1590 | WP_000013192.1 | peptide chain release factor 3 | - |
| KAF59_RS10630 (KAF59_10630) | 2352868..2353515 | - | 648 | WP_000854920.1 | LexA family transcriptional regulator | - |
| KAF59_RS10635 (KAF59_10635) | 2353633..2353884 | + | 252 | WP_000451746.1 | helix-turn-helix domain-containing protein | - |
| KAF59_RS10640 (KAF59_10640) | 2353940..2354809 | + | 870 | WP_001205851.1 | hypothetical protein | - |
| KAF59_RS10645 (KAF59_10645) | 2354796..2355458 | + | 663 | WP_001158521.1 | DUF6475 domain-containing protein | - |
| KAF59_RS10650 (KAF59_10650) | 2355445..2355993 | + | 549 | WP_000848909.1 | lytic transglycosylase domain-containing protein | - |
| KAF59_RS10655 (KAF59_10655) | 2355990..2356289 | + | 300 | WP_000210563.1 | flagellar transcriptional regulator FlhD | - |
| KAF59_RS10660 (KAF59_10660) | 2356286..2356819 | + | 534 | WP_000566752.1 | FlhC family transcriptional regulator | - |
| KAF59_RS10665 (KAF59_10665) | 2356874..2357305 | + | 432 | WP_001883790.1 | entry exclusion protein EexS | - |
| KAF59_RS10670 (KAF59_10670) | 2357338..2360907 | - | 3570 | WP_000263682.1 | conjugal transfer protein TraG N-terminal domain-containing protein | - |
| KAF59_RS10675 (KAF59_10675) | 2360911..2362299 | - | 1389 | WP_000755290.1 | conjugal transfer protein TraH | - |
| KAF59_RS10680 (KAF59_10680) | 2362302..2363246 | - | 945 | WP_001260106.1 | thioredoxin family protein | - |
| KAF59_RS10685 (KAF59_10685) | 2363981..2367787 | + | 3807 | WP_000838535.1 | response regulator | - |
| KAF59_RS10690 (KAF59_10690) | 2367793..2368722 | + | 930 | WP_001271628.1 | Response regulator PleD | VF |
| KAF59_RS10695 (KAF59_10695) | 2368985..2369692 | - | 708 | WP_000989527.1 | hypothetical protein | - |
| KAF59_RS10700 (KAF59_10700) | 2369783..2370856 | - | 1074 | WP_001207588.1 | primase-helicase zinc-binding domain-containing protein | - |
| KAF59_RS10705 (KAF59_10705) | 2370948..2371289 | - | 342 | WP_001014427.1 | hypothetical protein | - |
| KAF59_RS10710 (KAF59_10710) | 2371289..2371786 | - | 498 | WP_000791199.1 | DNA repair protein RadC | - |
| KAF59_RS10715 (KAF59_10715) | 2371868..2373523 | - | 1656 | WP_001016321.1 | VWA domain-containing protein | - |
| KAF59_RS10720 (KAF59_10720) | 2373593..2374033 | - | 441 | WP_001192020.1 | hypothetical protein | - |
| KAF59_RS10725 (KAF59_10725) | 2374095..2375048 | - | 954 | WP_000027442.1 | DUF3150 domain-containing protein | - |
| KAF59_RS10730 (KAF59_10730) | 2375147..2375914 | - | 768 | WP_000970192.1 | hypothetical protein | - |
| KAF59_RS10735 (KAF59_10735) | 2375914..2376873 | - | 960 | WP_000139693.1 | CbbQ/NirQ/NorQ C-terminal domain-containing protein | - |
| KAF59_RS10740 (KAF59_10740) | 2377083..2378099 | - | 1017 | WP_000862954.1 | YqaJ viral recombinase family protein | - |
| KAF59_RS10745 (KAF59_10745) | 2378160..2378303 | - | 144 | WP_000167275.1 | hypothetical protein | - |
| KAF59_RS10750 (KAF59_10750) | 2378385..2379203 | - | 819 | WP_000414661.1 | phage recombination protein Bet | - |
| KAF59_RS10755 (KAF59_10755) | 2379283..2379702 | - | 420 | WP_000795987.1 | single-stranded DNA-binding protein | - |
| KAF59_RS10760 (KAF59_10760) | 2379718..2380044 | - | 327 | WP_000455721.1 | hypothetical protein | - |
| KAF59_RS10765 (KAF59_10765) | 2380412..2381014 | + | 603 | WP_000035786.1 | hypothetical protein | - |
| KAF59_RS10770 (KAF59_10770) | 2381155..2381838 | + | 684 | WP_001082329.1 | endonuclease | - |
| KAF59_RS10775 (KAF59_10775) | 2381951..2383015 | + | 1065 | WP_000852158.1 | hypothetical protein | - |
| KAF59_RS10780 (KAF59_10780) | 2383015..2384100 | + | 1086 | WP_000678781.1 | hypothetical protein | - |
| KAF59_RS10785 (KAF59_10785) | 2384107..2384787 | + | 681 | WP_000838013.1 | hypothetical protein | - |
| KAF59_RS10790 (KAF59_10790) | 2384880..2388578 | - | 3699 | WP_000805218.1 | conjugal transfer protein TraN | - |
| KAF59_RS10795 (KAF59_10795) | 2388581..2389609 | - | 1029 | WP_000735887.1 | TraU family protein | - |
| KAF59_RS10800 (KAF59_10800) | 2389593..2390717 | - | 1125 | WP_025989328.1 | TrbC family F-type conjugative pilus assembly protein | - |
| KAF59_RS10805 (KAF59_10805) | 2390728..2391240 | - | 513 | WP_001166556.1 | S26 family signal peptidase | - |
| KAF59_RS10810 (KAF59_10810) | 2391224..2391571 | - | 348 | WP_001044650.1 | hypothetical protein | - |
| KAF59_RS10815 (KAF59_10815) | 2391564..2393963 | - | 2400 | WP_000648041.1 | type IV secretion system protein TraC | - |
| KAF59_RS10820 (KAF59_10820) | 2393963..2394655 | - | 693 | WP_001228924.1 | DsbC family protein | - |
| KAF59_RS10825 (KAF59_10825) | 2394787..2395725 | - | 939 | WP_000356587.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin Detail |
| KAF59_RS10830 (KAF59_10830) | 2395718..2396509 | - | 792 | WP_000095577.1 | type IV toxin-antitoxin system AbiEi family antitoxin | Antitoxin Detail |
| KAF59_RS10835 (KAF59_10835) | 2396730..2397116 | - | 387 | WP_000180225.1 | TraA family conjugative transfer protein | - |
| KAF59_RS10840 (KAF59_10840) | 2397113..2397685 | - | 573 | WP_139057167.1 | type IV conjugative transfer system lipoprotein TraV | - |
| KAF59_RS10845 (KAF59_10845) | 2397760..2399049 | - | 1290 | WP_001883765.1 | TraB/VirB10 family protein | - |
| KAF59_RS10850 (KAF59_10850) | 2399052..2399948 | - | 897 | WP_032467354.1 | type-F conjugative transfer system secretin TraK | - |
| KAF59_RS10855 (KAF59_10855) | 2399932..2400558 | - | 627 | WP_000667169.1 | TraE/TraK family type IV conjugative transfer system protein | - |
| KAF59_RS10860 (KAF59_10860) | 2400555..2400836 | - | 282 | WP_000433889.1 | type IV conjugative transfer system protein TraL | - |
| KAF59_RS10865 (KAF59_10865) | 2401017..2401340 | + | 324 | WP_000118545.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| KAF59_RS10870 (KAF59_10870) | 2401337..2401615 | + | 279 | WP_000058216.1 | helix-turn-helix transcriptional regulator | Antitoxin Detail |
| KAF59_RS10875 (KAF59_10875) | 2401641..2402276 | - | 636 | WP_000033753.1 | DUF4400 domain-containing protein | - |
| KAF59_RS10880 (KAF59_10880) | 2402263..2402823 | - | 561 | WP_000546510.1 | hypothetical protein | - |
| KAF59_RS10885 (KAF59_10885) | 2402833..2404653 | - | 1821 | WP_000661887.1 | conjugative transfer system coupling protein TraD | - |
| KAF59_RS10890 (KAF59_10890) | 2404702..2406852 | - | 2151 | WP_000475917.1 | MobH family relaxase | - |
| KAF59_RS10895 (KAF59_10895) | 2407007..2409658 | - | 2652 | WP_000494309.1 | AAA family ATPase | - |
| KAF59_RS10900 (KAF59_10900) | 2409702..2411732 | - | 2031 | WP_197708382.1 | protease Lon-related BREX system protein BrxL | - |
| KAF59_RS10905 (KAF59_10905) | 2411794..2414451 | - | 2658 | WP_001167232.1 | BREX-1 system phosphatase PglZ type A | - |
| KAF59_RS10910 (KAF59_10910) | 2414451..2418023 | - | 3573 | WP_001090323.1 | BREX-1 system adenine-specific DNA-methyltransferase PglX | - |
| KAF59_RS10915 (KAF59_10915) | 2418027..2418785 | - | 759 | WP_000605305.1 | hypothetical protein | - |
| KAF59_RS10920 (KAF59_10920) | 2418782..2419951 | - | 1170 | WP_000595812.1 | AAA family ATPase | - |
| KAF59_RS10925 (KAF59_10925) | 2419962..2423639 | - | 3678 | WP_000687849.1 | BREX system P-loop protein BrxC | - |
| KAF59_RS10930 (KAF59_10930) | 2423658..2424242 | - | 585 | WP_000645939.1 | DUF1788 domain-containing protein | - |
| KAF59_RS10935 (KAF59_10935) | 2424239..2424838 | - | 600 | WP_001080201.1 | DUF1819 family protein | - |
| KAF59_RS10940 (KAF59_10940) | 2424848..2425774 | - | 927 | WP_001883760.1 | WYL domain-containing protein | - |
| KAF59_RS10945 (KAF59_10945) | 2425843..2426157 | - | 315 | WP_000284109.1 | hypothetical protein | - |
| KAF59_RS10950 (KAF59_10950) | 2426231..2427139 | - | 909 | WP_000196207.1 | 3'-5' exonuclease | - |
| KAF59_RS10955 (KAF59_10955) | 2427522..2427779 | - | 258 | WP_000182836.1 | hypothetical protein | - |
| KAF59_RS10960 (KAF59_10960) | 2427778..2428227 | + | 450 | WP_000116661.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| KAF59_RS10965 (KAF59_10965) | 2428235..2428504 | + | 270 | WP_001883756.1 | hypothetical protein | - |
| KAF59_RS10970 (KAF59_10970) | 2429153..2430460 | - | 1308 | Protein_2133 | Tn3 family transposase TnpA_ISShfr9 | Transposase |
| KAF59_RS10975 (KAF59_10975) | 2430574..2431167 | - | 594 | WP_000107352.1 | Tn3 family transposase TnpA_IS3000 | Transposase |
| KAF59_RS10980 (KAF59_10980) | 2431451..2432623 | + | 1173 | WP_001142611.1 | translesion error-prone DNA polymerase V subunit UmuC | - |
| KAF59_RS10985 (KAF59_10985) | 2432634..2433077 | - | 444 | WP_000348526.1 | conjugative transfer protein MobI(A/C) | - |
| KAF59_RS10990 (KAF59_10990) | 2433542..2434516 | + | 975 | WP_000497805.1 | ParM/StbA family protein | - |
| KAF59_RS10995 (KAF59_10995) | 2434519..2434788 | + | 270 | WP_001267005.1 | hypothetical protein | - |
| KAF59_RS11000 (KAF59_11000) | 2434790..2436031 | + | 1242 | WP_001218617.1 | Prophage integrase IntS ; Integrase | Integrase |
| KAF59_RS11005 (KAF59_11005) | 2436048..2436242 | - | 195 | WP_000127614.1 | DNA-binding protein | - |
| KAF59_RS11010 (KAF59_11010) | 2437126..2439183 | + | 2058 | WP_000160066.1 | putative signaling protein | VF |
| KAF59_RS11015 (KAF59_11015) | 2439172..2439621 | - | 450 | WP_000214238.1 | Ribosomal-protein-alanine acetyltransferase | VF |
| KAF59_RS11020 (KAF59_11020) | 2439618..2440025 | - | 408 | WP_000953212.1 | DNA polymerase III subunit psi | - |
| KAF59_RS11025 (KAF59_11025) | 2440136..2440639 | - | 504 | WP_000908540.1 | N-acetyltransferase | - |
| KAF59_RS11030 (KAF59_11030) | 2440623..2441150 | - | 528 | WP_000932672.1 | SCP2 domain-containing protein | - |
| KAF59_RS11035 (KAF59_11035) | 2441383..2443437 | + | 2055 | WP_001111411.1 | bifunctional diguanylate cyclase/phosphodiesterase | - |
| KAF59_RS11040 (KAF59_11040) | 2443545..2444558 | + | 1014 | WP_000421327.1 | peptidase U32 family protein | - |
| KAF59_RS11045 (KAF59_11045) | 2444570..2445448 | + | 879 | WP_000872504.1 | U32 family peptidase | - |
| KAF59_RS11050 (KAF59_11050) | 2445501..2446838 | - | 1338 | WP_000981941.1 | sodium-coupled multidrug efflux MATE transporter VcrM | - |
| KAF59_RS11055 (KAF59_11055) | 2446885..2447292 | - | 408 | WP_000887847.1 | MarR family transcriptional regulator | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|