MGE detailed information
MGE type: Conjugative plasmid MGE length: 115574 bp
Accession: NZ_CP069864 Location: 1..115574 Organism: Escherichia coli strain FDAARGOS_1282 Replicon: plasmid unnamed1
Accession: NZ_CP069864 Location: 1..115574 Organism: Escherichia coli strain FDAARGOS_1282 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6K12_RS00010 (523) | 523..621 | - | 99 | Protein_1 | IS1 family transposase | - |
| I6K12_RS00015 (650) | 650..1960 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| I6K12_RS00020 (2245) | 2245..2646 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| I6K12_RS00025 (2579) | 2579..2836 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| I6K12_RS00030 (2929) | 2929..3582 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| I6K12_RS00035 (4520) | 4520..5377 | - | 858 | WP_000131001.1 | incFII family plasmid replication initiator RepA | - |
| I6K12_RS00040 (5370) | 5370..5444 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| I6K12_RS00045 (5677) | 5677..5937 | - | 261 | WP_000078109.1 | replication regulatory protein RepA | - |
| I6K12_RS00050 (6177) | 6177..6767 | - | 591 | WP_000766808.1 | DUF2726 domain-containing protein | - |
| I6K12_RS00055 (6805) | 6805..7014 | - | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| I6K12_RS00060 (7060) | 7060..7521 | - | 462 | WP_001233838.1 | thermonuclease family protein | - |
| I6K12_RS00065 (7766) | 7766..7978 | - | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| I6K12_RS00070 (8107) | 8107..8667 | - | 561 | WP_000139321.1 | fertility inhibition protein FinO | - |
| I6K12_RS00075 (8770) | 8770..9630 | - | 861 | WP_000704523.1 | putative protein YcjY | VF |
| I6K12_RS00080 (9689) | 9689..10435 | - | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| I6K12_RS00085 (10455) | 10455..15725 | - | 5271 | WP_204667168.1 | Multifunctional conjugation protein TraI | Relaxase |
| I6K12_RS00090 (15725) | 15725..17905 | - | 2181 | WP_001538091.1 | type IV conjugative transfer system coupling protein TraD | - |
| I6K12_RS00095 (17956) | 17956..18693 | - | 738 | WP_000199901.1 | hypothetical protein | - |
| I6K12_RS00100 (18896) | 18896..19627 | - | 732 | WP_000782451.1 | conjugal transfer complement resistance protein TraT | - |
| I6K12_RS00105 (19676) | 19676..20161 | - | 486 | WP_000605869.1 | hypothetical protein | - |
| I6K12_RS00110 (20177) | 20177..22999 | - | 2823 | WP_001007080.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| I6K12_RS00115 (22996) | 22996..24369 | - | 1374 | WP_000944331.1 | conjugal transfer pilus assembly protein TraH | - |
| I6K12_RS00120 (24356) | 24356..24748 | - | 393 | WP_000660700.1 | F-type conjugal transfer protein TrbF | - |
| I6K12_RS00125 (24729) | 24729..25076 | - | 348 | WP_001309242.1 | P-type conjugative transfer protein TrbJ | - |
| I6K12_RS00130 (25006) | 25006..25551 | - | 546 | WP_000059830.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| I6K12_RS00135 (25538) | 25538..25822 | - | 285 | WP_000624107.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| I6K12_RS00140 (25903) | 25903..26238 | + | 336 | WP_000736414.1 | hypothetical protein | - |
| I6K12_RS00145 (26219) | 26219..26560 | - | 342 | WP_001298557.1 | conjugal transfer protein TrbA | - |
| I6K12_RS00150 (26574) | 26574..27317 | - | 744 | WP_001030385.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| I6K12_RS00155 (27310) | 27310..27567 | - | 258 | WP_000864314.1 | conjugal transfer protein TrbE | - |
| I6K12_RS00160 (27594) | 27594..29444 | - | 1851 | WP_000821859.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| I6K12_RS00165 (29441) | 29441..30079 | - | 639 | WP_001080251.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| I6K12_RS00170 (30088) | 30088..30393 | - | 306 | WP_000224418.1 | hypothetical protein | - |
| I6K12_RS00175 (30423) | 30423..31415 | - | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| I6K12_RS00180 (31412) | 31412..32044 | - | 633 | WP_001203736.1 | type-F conjugative transfer system protein TraW | - |
| I6K12_RS00185 (32041) | 32041..32427 | - | 387 | WP_000214082.1 | type-F conjugative transfer system protein TrbI | - |
| I6K12_RS00190 (32424) | 32424..35054 | - | 2631 | WP_000069778.1 | type IV secretion system protein TraC | - |
| I6K12_RS00195 (35421) | 35421..35639 | - | 219 | WP_000556746.1 | hypothetical protein | - |
| I6K12_RS00200 (35719) | 35719..36192 | - | 474 | WP_000549566.1 | hypothetical protein | - |
| I6K12_RS00205 (36185) | 36185..36406 | - | 222 | WP_001278694.1 | conjugal transfer protein TraR | - |
| I6K12_RS00210 (36541) | 36541..37056 | - | 516 | WP_000809889.1 | type IV conjugative transfer system lipoprotein TraV | - |
| I6K12_RS00215 (37053) | 37053..37305 | - | 253 | Protein_42 | conjugal transfer protein TrbG | - |
| I6K12_RS00220 (37298) | 37298..37618 | - | 321 | WP_001057275.1 | conjugal transfer protein TrbD | - |
| I6K12_RS00225 (37605) | 37605..38195 | - | 591 | WP_000002787.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| I6K12_RS00230 (38185) | 38185..39612 | - | 1428 | WP_000146665.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| I6K12_RS00235 (39612) | 39612..40340 | - | 729 | WP_001230787.1 | type-F conjugative transfer system secretin TraK | - |
| I6K12_RS00240 (40327) | 40327..40893 | - | 567 | WP_000399776.1 | type IV conjugative transfer system protein TraE | - |
| I6K12_RS00245 (40915) | 40915..41226 | - | 312 | WP_000012100.1 | type IV conjugative transfer system protein TraL | - |
| I6K12_RS00250 (41241) | 41241..41600 | - | 360 | WP_001098988.1 | type IV conjugative transfer system pilin TraA | - |
| I6K12_RS00255 (41634) | 41634..41861 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| I6K12_RS00260 (41955) | 41955..42641 | - | 687 | WP_000332487.1 | PAS domain-containing protein | - |
| I6K12_RS00265 (42835) | 42835..43218 | - | 384 | WP_001151562.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| I6K12_RS00270 (43549) | 43549..44151 | + | 603 | WP_001323326.1 | hypothetical protein | VF |
| I6K12_RS00275 (44447) | 44447..45268 | - | 822 | WP_001234489.1 | DUF932 domain-containing protein | - |
| I6K12_RS00280 (45387) | 45387..45674 | - | 288 | WP_000107526.1 | hypothetical protein | - |
| I6K12_RS25675 (45975) | 45975..46272 | + | 298 | Protein_56 | hypothetical protein | - |
| I6K12_RS00285 (46590) | 46590..46715 | - | 126 | WP_096937776.1 | type I toxin-antitoxin system Hok family toxin | - |
| I6K12_RS25680 (46657) | 46657..46806 | - | 150 | Protein_58 | DUF5431 family protein | - |
| - (46813) | 46813..47012 | - | 200 | NuclAT_0 | - | - |
| - (46813) | 46813..47012 | - | 200 | NuclAT_0 | - | - |
| - (46813) | 46813..47012 | - | 200 | NuclAT_0 | - | - |
| - (46813) | 46813..47012 | - | 200 | NuclAT_0 | - | - |
| I6K12_RS00290 (46980) | 46980..47743 | - | 764 | Protein_59 | plasmid SOS inhibition protein A | - |
| I6K12_RS00295 (47740) | 47740..48174 | - | 435 | WP_000845910.1 | conjugation system SOS inhibitor PsiB | - |
| I6K12_RS00300 (48229) | 48229..50187 | - | 1959 | WP_001145501.1 | ParB/RepB/Spo0J family partition protein | - |
| I6K12_RS00305 (50246) | 50246..50479 | - | 234 | WP_000006018.1 | DUF905 domain-containing protein | - |
| I6K12_RS00310 (50536) | 50536..51063 | - | 528 | WP_000290833.1 | single-stranded DNA-binding protein | - |
| I6K12_RS00315 (51365) | 51365..51817 | + | 453 | WP_024185774.1 | hypothetical protein | - |
| I6K12_RS00320 (51903) | 51903..52466 | - | 564 | WP_001298559.1 | class I SAM-dependent methyltransferase | - |
| I6K12_RS00325 (52513) | 52513..53874 | - | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| I6K12_RS00330 (53926) | 53926..54156 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| I6K12_RS00335 (55194) | 55194..55385 | - | 192 | WP_001027493.1 | hypothetical protein | - |
| I6K12_RS00340 (55382) | 55382..55804 | - | 423 | WP_000271762.1 | DUF1380 family protein | - |
| I6K12_RS00345 (55851) | 55851..56276 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| I6K12_RS00350 (56692) | 56692..57462 | - | 771 | WP_001004562.1 | hypothetical protein | - |
| I6K12_RS00355 (57507) | 57507..58025 | - | 519 | WP_223364201.1 | DUF1380 family protein | - |
| I6K12_RS00360 (57955) | 57955..58176 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| I6K12_RS00365 (58177) | 58177..58860 | - | 684 | WP_000086169.1 | DNA methylase | - |
| I6K12_RS00370 (58936) | 58936..59247 | - | 312 | WP_001310011.1 | hypothetical protein | - |
| I6K12_RS00375 (59244) | 59244..60146 | - | 903 | WP_001310012.1 | DUF1281 domain-containing protein | - |
| I6K12_RS00380 (60565) | 60565..61785 | - | 1221 | WP_000343766.1 | ISL3 family transposase ISEc53 | Transposase |
| I6K12_RS00385 (61804) | 61804..62322 | - | 519 | WP_000115885.1 | hypothetical protein | VF |
| I6K12_RS00390 (62457) | 62457..62705 | + | 249 | WP_000619112.1 | DinI-like family protein | - |
| I6K12_RS00395 (62702) | 62702..63139 | + | 438 | WP_000109079.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| I6K12_RS00400 (63139) | 63139..64160 | + | 1022 | Protein_81 | translesion error-prone DNA polymerase V subunit UmuC | - |
| I6K12_RS00405 (64262) | 64262..65434 | + | 1173 | WP_000952372.1 | IS21 family transposase IS21 | Transposase |
| I6K12_RS00410 (65434) | 65434..66231 | + | 798 | WP_000544830.1 | IS21 family transposase IS21 | Transposase |
| I6K12_RS00415 (66293) | 66293..66544 | + | 252 | Protein_84 | DUF4113 domain-containing protein | - |
| I6K12_RS00420 (66549) | 66549..66941 | - | 393 | WP_000340835.1 | plasmid partitioning/stability family protein | - |
| I6K12_RS00425 (66946) | 66946..67917 | - | 972 | WP_001103694.1 | plasmid segregation protein ParM | - |
| I6K12_RS00430 (68146) | 68146..68790 | + | 645 | WP_000633911.1 | AAA family ATPase | - |
| I6K12_RS00435 (68784) | 68784..69059 | + | 276 | WP_000239529.1 | hypothetical protein | - |
| I6K12_RS00440 (69197) | 69197..70006 | - | 810 | WP_000016979.1 | site-specific integrase | - |
| I6K12_RS00445 (70007) | 70007..70312 | - | 306 | WP_001159871.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| I6K12_RS00450 (70314) | 70314..70532 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| I6K12_RS00455 (72854) | 72854..73495 | + | 642 | WP_000990667.1 | hypothetical protein | - |
| I6K12_RS00460 (74670) | 74670..75647 | + | 978 | WP_001309253.1 | RepB family plasmid replication initiator protein | - |
| I6K12_RS00465 (75890) | 75890..76630 | - | 741 | WP_001066952.1 | tyrosine-type recombinase/integrase | - |
| I6K12_RS00470 (76751) | 76751..76939 | - | 189 | WP_001309252.1 | hypothetical protein | - |
| I6K12_RS00475 (77306) | 77306..78475 | + | 1170 | WP_001072358.1 | hypothetical protein | - |
| I6K12_RS00480 (78701) | 78701..78876 | - | 176 | Protein_97 | IS3 family transposase | - |
| I6K12_RS00485 (79322) | 79322..79594 | - | 273 | WP_001322642.1 | adhesin biosynthesis transcription regulatory family protein | - |
| I6K12_RS00490 (80131) | 80131..80555 | - | 425 | Protein_99 | IS3 family transposase IS2 | Transposase |
| I6K12_RS00495 (80837) | 80837..82807 | + | 1971 | WP_001298664.1 | Hemin receptor | VF |
| I6K12_RS00500 (82814) | 82814..83605 | + | 792 | WP_000977394.1 | DUF4198 domain-containing protein | - |
| I6K12_RS00505 (83668) | 83668..84276 | - | 609 | Protein_102 | IS66 family transposase ISEc22 | Transposase |
| I6K12_RS00510 (84344) | 84344..85126 | - | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| I6K12_RS00515 (85123) | 85123..86145 | - | 1023 | WP_001310017.1 | IS21 family transposase IS100kyp | Transposase |
| I6K12_RS00520 (86231) | 86231..87176 | - | 946 | Protein_105 | IS66 family transposase ISEc8 | Transposase |
| I6K12_RS00525 (87225) | 87225..87572 | - | 348 | WP_000612626.1 | IS66 family transposase ISKpn24 | Transposase |
| I6K12_RS00530 (87569) | 87569..87973 | - | 405 | WP_000839179.1 | IS66 family transposase ISEc22 | Transposase |
| I6K12_RS00535 (88053) | 88053..88391 | - | 339 | Protein_108 | IS3 family transposase IS629 | Transposase |
| I6K12_RS00540 (88475) | 88475..89983 | - | 1509 | WP_001189113.1 | group II intron reverse transcriptase/maturase | - |
| I6K12_RS00545 (90656) | 90656..91395 | - | 740 | Protein_110 | IS3 family transposase IS629 | Transposase |
| I6K12_RS00550 (91421) | 91421..91726 | + | 306 | Protein_111 | IS91 family transposase ISSbo1 | Transposase |
| I6K12_RS00555 (92249) | 92249..93424 | - | 1176 | WP_001020413.1 | putative protein YncE | VF |
| I6K12_RS00560 (93493) | 93493..94785 | - | 1293 | Protein_113 | TonB-dependent receptor | - |
| I6K12_RS00565 (94841) | 94841..95538 | + | 698 | WP_151884388.1 | IS1 family transposase IS1X2 | Transposase |
| I6K12_RS00570 (95553) | 95553..95771 | + | 219 | Protein_115 | IS4 family transposase | - |
| I6K12_RS00575 (95821) | 95821..96525 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| I6K12_RS00580 (96584) | 96584..97333 | - | 750 | Protein_117 | IS91 family transposase ISAzo26 | Transposase |
| I6K12_RS00585 (97491) | 97491..97964 | + | 474 | WP_001389366.1 | Dihydrofolate reductase type 1 | ARG |
| I6K12_RS00590 (98095) | 98095..98883 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| I6K12_RS00595 (99089) | 99089..99436 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| I6K12_RS00600 (99430) | 99430..100269 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| I6K12_RS00605 (100397) | 100397..100600 | + | 204 | WP_000376616.1 | hypothetical protein | - |
| I6K12_RS00610 (100756) | 100756..101961 | + | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| I6K12_RS00615 (101972) | 101972..102277 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| I6K12_RS00620 (102321) | 102321..102386 | + | 66 | Protein_125 | EAL domain-containing protein | - |
| I6K12_RS00625 (102504) | 102504..103268 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| I6K12_RS00630 (103761) | 103761..104345 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| I6K12_RS00635 (104345) | 104345..105583 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| I6K12_RS00640 (105580) | 105580..106485 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| I6K12_RS00645 (106607) | 106607..107311 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| I6K12_RS00650 (107372) | 107372..107548 | + | 177 | Protein_131 | replication protein C, IncQ-type | - |
| I6K12_RS00655 (107856) | 107856..108671 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| I6K12_RS00660 (108732) | 108732..109535 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| I6K12_RS00665 (109535) | 109535..110371 | + | 837 | WP_000480972.1 | hypothetical protein | ARG |
| I6K12_RS00670 (110425) | 110425..110661 | + | 237 | WP_042005022.1 | hypothetical protein | - |
| I6K12_RS00675 (110693) | 110693..111319 | - | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| I6K12_RS00680 (111425) | 111425..112624 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| I6K12_RS00685 (112656) | 112656..113516 | - | 861 | WP_000493383.1 | EamA family transporter | - |
| I6K12_RS00690 (113525) | 113525..114031 | - | 507 | Protein_139 | DNA-binding domain-containing protein | - |
| I6K12_RS00695 (114084) | 114084..114788 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|