MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 134460 bp
Accession: NZ_CP065927 Location: 955464..1089923 Organism: Streptococcus pyogenes strain emm9ST603 Replicon: chromosome
Accession: NZ_CP065927 Location: 955464..1089923 Organism: Streptococcus pyogenes strain emm9ST603 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JAN99_RS04755 () | 951040..952017 | - | 978 | WP_002984655.1 | nucleoid-associated protein | - |
| JAN99_RS04760 () | 952024..953280 | - | 1257 | WP_136093778.1 | serine hydroxymethyltransferase | - |
| JAN99_RS04765 () | 953270..953722 | - | 453 | WP_020833473.1 | GNAT family N-acetyltransferase | - |
| JAN99_RS04770 () | 953740..954330 | - | 591 | WP_002984663.1 | threonylcarbamoyl-AMP synthase | - |
| JAN99_RS04775 () | 954314..955153 | - | 840 | WP_002989798.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| JAN99_RS04780 () | 955153..956232 | - | 1080 | WP_002989800.1 | peptide chain release factor 1 | - |
| JAN99_RS04785 () | 956267..956836 | - | 570 | WP_136116155.1 | thymidine kinase | - |
| JAN99_RS04790 () | 956974..957159 | + | 186 | WP_002984671.1 | 4-oxalocrotonate tautomerase | - |
| JAN99_RS04795 () | 957212..958150 | + | 939 | WP_023612975.1 | FAD:protein FMN transferase | - |
| JAN99_RS04800 () | 958214..959497 | - | 1284 | WP_111693212.1 | purine permease | - |
| JAN99_RS04805 () | 959497..960078 | - | 582 | WP_002984677.1 | xanthine phosphoribosyltransferase | - |
| JAN99_RS04810 () | 960383..961366 | - | 984 | WP_111693211.1 | GMP reductase | - |
| JAN99_RS04815 () | 961644..963170 | - | 1527 | WP_161230186.1 | ABC transporter permease/substrate-binding protein | - |
| JAN99_RS04820 () | 963163..963891 | - | 729 | WP_010922297.1 | Carnitine transport ATP-binding protein OpuCA | VF |
| JAN99_RS04825 () | 964311..965000 | + | 690 | WP_111693209.1 | multidrug transporter | - |
| JAN99_RS04830 () | 965194..965949 | - | 756 | WP_136116157.1 | NADP-dependent 3-hydroxy acid dehydrogenase YdfG | VF |
| JAN99_RS04835 () | 966076..967071 | - | 996 | WP_002984691.1 | phosphate acetyltransferase | - |
| JAN99_RS04840 () | 967075..967980 | - | 906 | WP_002989820.1 | RluA family pseudouridine synthase | - |
| JAN99_RS04845 () | 967977..968813 | - | 837 | WP_002993124.1 | NAD kinase | - |
| JAN99_RS04850 () | 968788..969459 | - | 672 | WP_002984696.1 | GTP pyrophosphokinase family protein | - |
| JAN99_RS04855 () | 969547..970125 | + | 579 | WP_111693208.1 | CYTH domain-containing protein | - |
| JAN99_RS04860 () | 970265..971245 | + | 981 | WP_111693207.1 | ribose-phosphate diphosphokinase | - |
| JAN99_RS04865 () | 971242..972369 | + | 1128 | WP_063812029.1 | cysteine desulfurase | - |
| JAN99_RS04870 () | 972359..972706 | + | 348 | WP_002989831.1 | DUF1831 domain-containing protein | - |
| JAN99_RS04875 () | 972958..973602 | + | 645 | WP_002984705.1 | redox-sensing transcriptional repressor Rex | - |
| JAN99_RS04880 () | 973612..974307 | + | 696 | WP_002994402.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| JAN99_RS04885 () | 974309..974989 | - | 681 | WP_111693205.1 | DNA repair protein RadC | - |
| JAN99_RS04890 () | 975038..976186 | - | 1149 | WP_002989837.1 | AI-2E family transporter | - |
| JAN99_RS04895 () | 976345..976959 | - | 615 | WP_011017748.1 | hypothetical protein | - |
| JAN99_RS04900 () | 977122..978654 | - | 1533 | WP_002995354.1 | ClC family H(+)/Cl(-) exchange transporter | - |
| JAN99_RS04905 () | 978832..979563 | - | 732 | WP_136116159.1 | acid phosphatase AphA | - |
| JAN99_RS04910 () | 979799..980848 | + | 1050 | WP_002989842.1 | zinc-dependent alcohol dehydrogenase family protein | - |
| JAN99_RS04915 () | 980930..982096 | - | 1167 | WP_010922289.1 | NADP-dependent malic enzyme | - |
| JAN99_RS04920 () | 982127..983458 | - | 1332 | WP_111693204.1 | 2-hydroxycarboxylate transporter family protein | - |
| JAN99_RS04925 () | 983619..985160 | + | 1542 | WP_111693203.1 | sensor histidine kinase | - |
| JAN99_RS04930 () | 985141..985806 | + | 666 | WP_111693202.1 | response regulator | - |
| JAN99_RS04935 () | 985861..986934 | - | 1074 | WP_002984738.1 | ABC transporter substrate-binding protein | - |
| JAN99_RS04940 () | 986927..987703 | - | 777 | WP_014407560.1 | ABC transporter permease | - |
| JAN99_RS04945 () | 987700..988494 | - | 795 | WP_002984743.1 | ABC transporter permease | - |
| JAN99_RS04950 () | 988478..989632 | - | 1155 | WP_010922284.1 | Spermidine/putrescine import ATP-binding protein PotA | VF |
| JAN99_RS04955 () | 989678..990565 | - | 888 | WP_110002568.1 | UDP-N-acetylenolpyruvoylglucosamine reductase | VF |
| JAN99_RS04960 () | 990715..991215 | - | 501 | WP_002984757.1 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase | - |
| JAN99_RS04965 () | 991212..991571 | - | 360 | WP_111693201.1 | dihydroneopterin aldolase | - |
| JAN99_RS04970 () | 991578..992378 | - | 801 | WP_111693200.1 | dihydropteroate synthase | - |
| JAN99_RS04975 () | 992387..992971 | - | 585 | WP_002995330.1 | GTP cyclohydrolase I FolE | - |
| JAN99_RS04980 () | 993006..994283 | - | 1278 | WP_030127274.1 | bifunctional folylpolyglutamate synthase/dihydrofolate synthase | - |
| JAN99_RS04985 () | 994614..995576 | + | 963 | WP_063629246.1 | Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase | VF |
| JAN99_RS04990 () | 995693..996928 | - | 1236 | WP_080465237.1 | D-alanyl-D-alanine carboxypeptidase PBP3 | - |
| JAN99_RS04995 () | 997086..998273 | - | 1188 | Protein_925 | site-specific integrase | - |
| JAN99_RS05000 () | 998276..998496 | - | 221 | Protein_926 | DUF3173 family protein | - |
| JAN99_RS05010 () | 998797..999015 | - | 219 | WP_002989884.1 | helix-turn-helix domain-containing protein | - |
| JAN99_RS05015 () | 999207..999929 | - | 723 | WP_010922276.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| JAN99_RS05020 () | 999932..1000681 | - | 750 | WP_010922275.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| JAN99_RS05025 () | 1000687..1001376 | - | 690 | WP_010922274.1 | Fluoroquinolones export ATP-binding protein | VF |
| JAN99_RS05030 () | 1001458..1002077 | - | 620 | Protein_931 | Multidrug efflux ATP-binding/permease protein | VF |
| JAN99_RS05035 () | 1002192..1002332 | - | 141 | WP_002984803.1 | lantibiotic streptin | - |
| JAN99_RS05040 () | 1002480..1003826 | - | 1347 | WP_002984805.1 | HAMP domain-containing histidine kinase | - |
| JAN99_RS05045 () | 1003819..1004505 | - | 687 | WP_002984807.1 | response regulator transcription factor | - |
| JAN99_RS05050 () | 1004656..1005165 | - | 510 | Protein_935 | lantibiotic (srt) production protein | - |
| JAN99_RS05055 () | 1005236..1006341 | + | 1106 | WP_111693067.1 | IS3 family transposase ISSdy1 | Transposase |
| JAN99_RS05060 () | 1006378..1007349 | - | 972 | Protein_937 | relaxase/mobilization nuclease domain-containing protein | - |
| JAN99_RS05065 () | 1007467..1009269 | - | 1803 | WP_111693197.1 | group II intron reverse transcriptase/maturase | - |
| JAN99_RS05070 () | 1009842..1010234 | - | 393 | Protein_939 | relaxase/mobilization nuclease domain-containing protein | - |
| JAN99_RS05075 () | 1010221..1010586 | - | 366 | WP_111693196.1 | MobC family plasmid mobilization relaxosome protein | - |
| JAN99_RS05080 () | 1010596..1010955 | - | 360 | WP_111693195.1 | hypothetical protein | - |
| JAN99_RS05085 () | 1011282..1012424 | - | 1143 | WP_111693194.1 | AAA family ATPase | - |
| JAN99_RS05090 () | 1012425..1013213 | - | 789 | WP_029174746.1 | hypothetical protein | - |
| JAN99_RS05095 () | 1013229..1013996 | - | 768 | WP_111693193.1 | zeta toxin family protein | Toxin Detail |
| JAN99_RS05100 () | 1013996..1014472 | - | 477 | WP_111693192.1 | helix-turn-helix domain-containing protein | Antitoxin Detail |
| JAN99_RS05105 () | 1014542..1014829 | - | 288 | WP_111693191.1 | hypothetical protein | - |
| JAN99_RS05110 () | 1014874..1015269 | - | 396 | WP_111693190.1 | chemotaxis protein | - |
| JAN99_RS05115 () | 1015273..1015494 | - | 222 | WP_111693189.1 | hypothetical protein | - |
| JAN99_RS05125 () | 1016823..1016993 | - | 171 | WP_168641549.1 | hypothetical protein | - |
| JAN99_RS05130 () | 1016977..1017168 | - | 192 | WP_136116398.1 | thrombospondin type 3 repeat-containing protein | - |
| JAN99_RS05135 () | 1017169..1021931 | - | 4763 | Protein_952 | Agglutinin receptor | VF |
| JAN99_RS05140 () | 1022124..1023518 | - | 1395 | WP_111693187.1 | hypothetical protein | - |
| JAN99_RS05145 () | 1023525..1024367 | - | 843 | WP_111693186.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| JAN99_RS05150 () | 1024364..1024957 | - | 594 | WP_111693185.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| JAN99_RS05155 () | 1025189..1025824 | - | 636 | WP_111693184.1 | hypothetical protein | - |
| JAN99_RS05160 () | 1026168..1028972 | - | 2805 | WP_111693183.1 | CHAP domain-containing protein | - |
| JAN99_RS05165 () | 1028969..1029937 | - | 969 | WP_111693182.1 | type IV secretion system protein VirB4 | - |
| JAN99_RS05170 () | 1029942..1031615 | - | 1674 | WP_111693496.1 | group II intron reverse transcriptase/maturase | - |
| JAN99_RS05175 () | 1032144..1033631 | - | 1488 | WP_198462959.1 | type VI secretion protein | - |
| JAN99_RS05180 () | 1033588..1033941 | - | 354 | WP_136116403.1 | PrgI family protein | - |
| JAN99_RS05185 () | 1034003..1034857 | - | 855 | WP_111693180.1 | type IV secretion system protein | - |
| JAN99_RS05190 () | 1034874..1035116 | - | 243 | WP_001072180.1 | hypothetical protein | - |
| JAN99_RS05195 () | 1035134..1036954 | - | 1821 | WP_111693179.1 | type IV secretory system conjugative DNA transfer family protein | - |
| JAN99_RS05200 () | 1036954..1037442 | - | 489 | WP_111693178.1 | hypothetical protein | - |
| JAN99_RS05205 () | 1037519..1038100 | - | 582 | WP_111693177.1 | CPBP family intramembrane metalloprotease | - |
| JAN99_RS05210 () | 1038103..1038246 | - | 144 | Protein_967 | transcriptional regulator | - |
| JAN99_RS05220 () | 1039468..1039557 | - | 90 | Protein_969 | transcriptional regulator | - |
| JAN99_RS05225 () | 1039567..1039950 | - | 384 | WP_111693175.1 | hypothetical protein | - |
| JAN99_RS05230 () | 1039960..1040388 | - | 429 | WP_111693174.1 | hypothetical protein | - |
| JAN99_RS05235 () | 1040372..1041727 | - | 1356 | WP_136116409.1 | DNA (cytosine-5-)-methyltransferase | - |
| JAN99_RS05240 () | 1041884..1042708 | - | 825 | WP_111693172.1 | replication initiator protein A | - |
| JAN99_RS05245 () | 1042705..1042878 | - | 174 | WP_111693171.1 | hypothetical protein | - |
| JAN99_RS05250 () | 1043136..1043501 | - | 366 | WP_002984819.1 | 50S ribosomal protein L7/L12 | - |
| JAN99_RS05255 () | 1043566..1044066 | - | 501 | WP_002984821.1 | 50S ribosomal protein L10 | - |
| JAN99_RS05260 () | 1044402..1045778 | + | 1377 | WP_023079424.1 | tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE | - |
| JAN99_RS05265 () | 1045846..1047255 | - | 1410 | WP_023079436.1 | dipeptidase PepV | - |
| JAN99_RS05270 () | 1047380..1047982 | - | 603 | WP_111693170.1 | nitroreductase family protein | - |
| JAN99_RS05280 () | 1049386..1051185 | - | 1800 | WP_136116060.1 | excinuclease ABC subunit UvrC | - |
| JAN99_RS05285 () | 1051287..1052684 | - | 1398 | WP_002992908.1 | NAD-dependent succinate-semialdehyde dehydrogenase | - |
| JAN99_RS05290 () | 1052799..1053845 | - | 1047 | WP_111693168.1 | extracellular solute-binding protein | - |
| JAN99_RS05295 () | 1053839..1054627 | - | 789 | WP_002984836.1 | putative response regulatory protein | VF |
| JAN99_RS05300 () | 1054631..1056280 | - | 1650 | WP_012560683.1 | putative sensor-like histidine kinase | VF |
| JAN99_RS05305 () | 1056416..1057243 | - | 828 | WP_002989931.1 | PTS system mannose/fructose/sorbose family transporter subunit IID | - |
| JAN99_RS05310 () | 1057240..1058049 | - | 810 | WP_038434067.1 | PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC | - |
| JAN99_RS05315 () | 1058066..1058557 | - | 492 | WP_002989934.1 | PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB | - |
| JAN99_RS05320 () | 1058576..1059001 | - | 426 | WP_011528592.1 | PTS sugar transporter subunit IIA | - |
| JAN99_RS05325 () | 1059208..1060227 | - | 1020 | WP_038434066.1 | YeiH family protein | - |
| JAN99_RS05330 () | 1060357..1060794 | - | 438 | WP_038434065.1 | Peptide methionine sulfoxide reductase MsrB | VF |
| JAN99_RS05335 () | 1060980..1062299 | - | 1320 | WP_198462960.1 | Immunoglobulin G-binding protein H | VF |
| JAN99_RS05340 () | 1062492..1064324 | - | 1833 | WP_010922253.1 | translation elongation factor 4 | - |
| JAN99_RS05345 () | 1064448..1064853 | - | 406 | Protein_994 | nucleoside-diphosphate kinase | - |
| JAN99_RS05350 () | 1065237..1065899 | - | 663 | WP_063631343.1 | type II-A CRISPR-associated protein Csn2 | - |
| JAN99_RS05355 () | 1065889..1066230 | - | 342 | WP_011106805.1 | CRISPR-associated endonuclease Cas2 | - |
| JAN99_RS05360 () | 1066227..1067096 | - | 870 | WP_032460891.1 | type II CRISPR-associated endonuclease Cas1 | - |
| JAN99_RS05365 () | 1067096..1071199 | - | 4104 | WP_111693164.1 | type II CRISPR RNA-guided endonuclease Cas9 | - |
| JAN99_RS05370 () | 1071678..1072310 | - | 633 | WP_136116064.1 | TIGR01906 family membrane protein | - |
| JAN99_RS05375 () | 1072310..1073074 | - | 765 | WP_111693163.1 | TIGR01457 family HAD-type hydrolase | - |
| JAN99_RS05380 () | 1073074..1073826 | - | 753 | WP_111693162.1 | acyl-[acyl-carrier-protein] thioesterase | - |
| JAN99_RS05385 () | 1073836..1074966 | - | 1131 | WP_136116066.1 | oxygen-independent coproporphyrinogen III oxidase | - |
| JAN99_RS05390 () | 1075029..1075670 | - | 642 | WP_111693160.1 | hypothetical protein | - |
| JAN99_RS05395 () | 1075794..1077149 | - | 1356 | WP_011106808.1 | phosphoglucosamine mutase | - |
| JAN99_RS05400 () | 1077203..1078159 | - | 957 | WP_002984857.1 | YbbR-like domain-containing protein | - |
| JAN99_RS05405 () | 1078156..1079007 | - | 852 | WP_002984858.1 | diadenylate cyclase CdaA | - |
| JAN99_RS05410 () | 1079114..1080457 | + | 1344 | WP_168388526.1 | Mur ligase family protein | - |
| JAN99_RS05415 () | 1080457..1081248 | + | 792 | WP_063632464.1 | type 1 glutamine amidotransferase | - |
| JAN99_RS05420 () | 1081357..1082346 | - | 990 | WP_002992006.1 | Lipoate-protein ligase LplJ | VF |
| JAN99_RS05425 () | 1082579..1084996 | + | 2418 | WP_136116068.1 | Hyaluronate lyase | VF |
| JAN99_RS05430 () | 1085671..1087434 | - | 1764 | WP_111693157.1 | dihydrolipoyl dehydrogenase | - |
| JAN99_RS05435 () | 1087761..1089170 | - | 1410 | WP_011017711.1 | dihydrolipoamide acetyltransferase | - |
| JAN99_RS05440 () | 1089355..1090353 | - | 999 | WP_002989981.1 | alpha-ketoacid dehydrogenase subunit beta | - |
| JAN99_RS05445 () | 1090412..1091380 | - | 969 | WP_002989983.1 | thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha | - |
| JAN99_RS05450 () | 1091665..1093572 | - | 1908 | WP_111693155.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| JAN99_RS05455 () | 1093618..1093944 | - | 327 | WP_111693154.1 | hypothetical protein | - |
| JAN99_RS05460 () | 1093974..1094759 | - | 786 | WP_011184454.1 | esterase family protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|