MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 114994 bp
Accession: NZ_CP065784 Location: 374047..489040 Organism: Enterococcus faecalis strain 18-243 Replicon: chromosome
Accession: NZ_CP065784 Location: 374047..489040 Organism: Enterococcus faecalis strain 18-243 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I8F59_RS01860 (369417) | 369417..369890 | + | 474 | WP_002355361.1 | FeoA family protein | - |
| I8F59_RS01865 (369887) | 369887..372037 | + | 2151 | WP_002355363.1 | ferrous iron transport protein B | - |
| I8F59_RS01870 (372044) | 372044..372181 | + | 138 | WP_002355364.1 | hypothetical protein | - |
| I8F59_RS01875 (372458) | 372458..373627 | - | 1170 | WP_002355365.1 | tyrosine-type recombinase/integrase | - |
| I8F59_RS01880 (373671) | 373671..373901 | - | 231 | WP_002355366.1 | helix-turn-helix domain-containing protein | - |
| I8F59_RS01890 (374248) | 374248..375555 | - | 1308 | WP_002363023.1 | ISL3 family transposase IS1476 | Transposase |
| I8F59_RS01895 (375744) | 375744..375992 | + | 249 | Protein_349 | transposase | - |
| I8F59_RS01900 (376164) | 376164..376625 | + | 462 | Protein_350 | IS256 family transposase | - |
| I8F59_RS01905 (376930) | 376930..377967 | - | 1038 | WP_002355369.1 | PTS sugar transporter subunit IIC | - |
| I8F59_RS01910 (377993) | 377993..378931 | - | 939 | WP_002335374.1 | 2-dehydropantoate 2-reductase | - |
| I8F59_RS01915 (379456) | 379456..380055 | + | 600 | WP_202496543.1 | Tyrosine recombinase XerD | VF |
| I8F59_RS01920 (380104) | 380104..380814 | + | 711 | Protein_354 | Fic family protein | - |
| I8F59_RS01925 (380934) | 380934..381615 | + | 682 | Protein_355 | IS6 family transposase IS1297 | Transposase |
| I8F59_RS01930 (381839) | 381839..383026 | + | 1188 | WP_002386101.1 | UDP-N-acetyl-D-mannosamine dehydrogenase | VF |
| I8F59_RS01935 (383063) | 383063..384256 | + | 1194 | WP_002355375.1 | Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase | VF |
| I8F59_RS01940 (384414) | 384414..385373 | + | 960 | WP_000221326.1 | IS30 family transposase IS6770 | Transposase |
| I8F59_RS01945 (385547) | 385547..386143 | + | 597 | WP_002363024.1 | HTH domain-containing protein | - |
| I8F59_RS01955 (388193) | 388193..389542 | - | 1350 | WP_002355383.1 | FAD-dependent oxidoreductase | - |
| I8F59_RS01960 (389680) | 389680..390303 | - | 624 | WP_002355386.1 | cysteine hydrolase | - |
| I8F59_RS01965 (390330) | 390330..390494 | - | 165 | WP_002384811.1 | hypothetical protein | - |
| I8F59_RS01970 (390568) | 390568..391158 | - | 591 | WP_002355388.1 | hypothetical protein | VF |
| I8F59_RS01975 (391498) | 391498..391758 | + | 261 | WP_142954376.1 | hypothetical protein | - |
| I8F59_RS15265 (391908) | 391908..392786 | + | 879 | Protein_366 | ISL3 family transposase | - |
| I8F59_RS01990 (392902) | 392902..393183 | - | 282 | WP_010708995.1 | hypothetical protein | - |
| I8F59_RS01995 (393362) | 393362..394303 | + | 942 | WP_002355392.1 | alpha/beta fold hydrolase | - |
| I8F59_RS02000 (394348) | 394348..395607 | - | 1260 | WP_214333449.1 | IS256 family transposase ISLgar5 | Transposase |
| I8F59_RS15270 (395798) | 395798..396199 | - | 402 | Protein_370 | S24 family peptidase | - |
| I8F59_RS02010 (396162) | 396162..396398 | + | 237 | WP_002355395.1 | helix-turn-helix transcriptional regulator | - |
| I8F59_RS02015 (396817) | 396817..398931 | + | 2115 | WP_002355397.1 | ATP-dependent Clp protease ATP-binding subunit ClpX | VF |
| I8F59_RS02020 (399112) | 399112..400287 | - | 1176 | Protein_373 | IS256 family transposase | - |
| I8F59_RS02025 (400448) | 400448..401407 | - | 960 | WP_000221326.1 | IS30 family transposase IS6770 | Transposase |
| I8F59_RS02030 (401515) | 401515..402243 | - | 729 | WP_002355404.1 | GntR family transcriptional regulator | - |
| I8F59_RS02035 (402420) | 402420..403346 | + | 927 | WP_002355406.1 | hypothetical protein | - |
| I8F59_RS02040 (403363) | 403363..404646 | + | 1284 | WP_002363033.1 | PTS sugar transporter subunit IIC | - |
| I8F59_RS02045 (404838) | 404838..404960 | + | 123 | Protein_378 | topoisomerase | - |
| I8F59_RS02050 (405035) | 405035..405931 | + | 897 | WP_002363034.1 | ParA family protein | - |
| I8F59_RS02055 (406008) | 406008..406217 | + | 210 | WP_002363035.1 | peptide-binding protein | - |
| I8F59_RS02060 (406234) | 406234..406506 | + | 273 | WP_002326825.1 | antitoxin | Antitoxin Detail |
| I8F59_RS02065 (406508) | 406508..406816 | + | 309 | WP_002355414.1 | zeta toxin family protein | Toxin Detail |
| I8F59_RS02070 (406896) | 406896..407318 | - | 423 | WP_080005963.1 | tyrosine-type recombinase/integrase | - |
| I8F59_RS02075 (407369) | 407369..407869 | - | 501 | WP_002363039.1 | HAD family hydrolase | - |
| I8F59_RS02080 (407874) | 407874..408641 | - | 768 | WP_002355416.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| I8F59_RS02085 (409128) | 409128..409553 | + | 426 | WP_002355418.1 | galactose-6-phosphate isomerase subunit LacA | - |
| I8F59_RS02090 (409570) | 409570..410085 | + | 516 | WP_002345825.1 | galactose-6-phosphate isomerase subunit LacB | - |
| I8F59_RS02095 (410096) | 410096..411028 | + | 933 | WP_002363040.1 | tagatose-6-phosphate kinase | - |
| I8F59_RS02100 (411031) | 411031..412011 | + | 981 | WP_002355420.1 | tagatose-bisphosphate aldolase | - |
| I8F59_RS02105 (412039) | 412039..412356 | + | 318 | WP_002290550.1 | PTS lactose/cellobiose transporter subunit IIA | - |
| I8F59_RS02110 (412356) | 412356..414062 | + | 1707 | WP_002343085.1 | lactose-specific PTS transporter subunit EIIC | - |
| I8F59_RS02115 (414209) | 414209..415615 | + | 1407 | WP_002290548.1 | 6-phospho-beta-galactosidase | - |
| I8F59_RS02120 (415638) | 415638..415910 | + | 273 | WP_002381203.1 | DUF3884 family protein | - |
| I8F59_RS02125 (415931) | 415931..416830 | + | 900 | WP_002355424.1 | aldose 1-epimerase family protein | - |
| I8F59_RS02130 (417216) | 417216..417761 | + | 546 | Protein_395 | zeta toxin family protein | - |
| I8F59_RS02135 (417823) | 417823..418101 | - | 279 | WP_002384822.1 | Tn3 family transposase TnpR_ISRsp12 | Transposase |
| I8F59_RS02140 (418089) | 418089..418409 | - | 321 | WP_002381204.1 | Tn3 family transposase TnpR_TnShfr1 | Transposase |
| I8F59_RS15275 (418592) | 418592..419065 | + | 474 | WP_002384823.1 | Tn3 family transposase TnBth1 | Transposase |
| I8F59_RS15280 (419108) | 419108..420304 | + | 1197 | WP_002380047.1 | transposase | - |
| I8F59_RS15285 (420202) | 420202..421563 | + | 1362 | WP_002384824.1 | Tn3 family transposase TnBth1 | Transposase |
| I8F59_RS02150 (422027) | 422027..423001 | + | 975 | WP_002355428.1 | hypothetical protein | VF |
| I8F59_RS02155 (423446) | 423446..423751 | + | 306 | WP_002364917.1 | hypothetical protein | - |
| I8F59_RS02160 (423757) | 423757..424272 | + | 516 | WP_002364914.1 | hypothetical protein | - |
| I8F59_RS02165 (424524) | 424524..424706 | + | 183 | WP_002380048.1 | TfoX/Sxy family DNA transformation protein | - |
| I8F59_RS15290 (424649) | 424649..424780 | + | 132 | WP_002411583.1 | TfoX/Sxy family DNA transformation protein | - |
| I8F59_RS15295 (424867) | 424867..425109 | + | 243 | WP_002363049.1 | hypothetical protein | - |
| I8F59_RS02170 (425492) | 425492..426358 | + | 867 | WP_010711377.1 | hypothetical protein | - |
| I8F59_RS02175 (426497) | 426497..427093 | + | 597 | WP_010729897.1 | Tn3 family transposase TnpR_ISMex38 | Transposase |
| I8F59_RS02180 (427110) | 427110..427396 | + | 287 | Protein_409 | hypothetical protein | - |
| I8F59_RS02185 (427390) | 427390..427614 | + | 225 | WP_002363053.1 | ultraviolet resistance protein UvrA repressor UvrC | - |
| I8F59_RS02190 (427674) | 427674..427883 | + | 210 | WP_002363054.1 | hypothetical protein | - |
| I8F59_RS02195 (428225) | 428225..428497 | + | 273 | WP_002363055.1 | hypothetical protein | - |
| I8F59_RS02200 (428530) | 428530..428967 | - | 438 | WP_010729899.1 | hypothetical protein | - |
| I8F59_RS02205 (429131) | 429131..430090 | + | 960 | WP_000221326.1 | IS30 family transposase IS6770 | Transposase |
| I8F59_RS15300 (430581) | 430581..430898 | + | 318 | WP_002411208.1 | hypothetical protein | - |
| I8F59_RS02215 (430976) | 430976..431857 | + | 882 | WP_002363057.1 | S41 family peptidase | - |
| I8F59_RS02220 (432127) | 432127..432693 | + | 567 | WP_010717288.1 | alkaline shock response membrane anchor protein AmaP | - |
| I8F59_RS02225 (432710) | 432710..432901 | + | 192 | WP_002358517.1 | DUF2273 domain-containing protein | - |
| I8F59_RS02230 (432930) | 432930..433466 | + | 537 | WP_002364907.1 | Asp23/Gls24 family envelope stress response protein | - |
| I8F59_RS02235 (433741) | 433741..439356 | + | 5616 | WP_214333450.1 | hypothetical protein | VF |
| I8F59_RS02240 (439556) | 439556..440764 | + | 1209 | WP_002364905.1 | YSIRK-targeted surface antigen transcriptional regulator | - |
| I8F59_RS02245 (440894) | 440894..441244 | + | 351 | WP_021732862.1 | hypothetical protein | - |
| I8F59_RS02250 (441445) | 441445..441546 | - | 102 | Protein_423 | IS30 family transposase | - |
| I8F59_RS02255 (441534) | 441534..442271 | + | 738 | WP_002384835.1 | hypothetical protein | - |
| I8F59_RS02260 (442317) | 442317..442808 | - | 492 | WP_033591396.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| I8F59_RS15305 (442992) | 442992..443428 | + | 437 | Protein_426 | recombinase family protein | - |
| I8F59_RS02275 (443517) | 443517..444335 | - | 819 | WP_002363071.1 | MurR/RpiR family transcriptional regulator | - |
| I8F59_RS02280 (444492) | 444492..445199 | + | 708 | WP_002363072.1 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
| I8F59_RS02285 (445192) | 445192..446694 | + | 1503 | WP_002363073.1 | PTS transporter subunit EIIC | - |
| I8F59_RS02290 (446705) | 446705..447187 | + | 483 | WP_002358535.1 | PTS glucose transporter subunit IIA | - |
| I8F59_RS02295 (447820) | 447820..448584 | - | 765 | WP_002358536.1 | YibE/F family protein | - |
| I8F59_RS02300 (448571) | 448571..449635 | - | 1065 | WP_002363074.1 | YibE/F family protein | - |
| I8F59_RS02305 (449974) | 449974..450147 | + | 174 | WP_002411201.1 | 50S ribosomal protein L32 | - |
| I8F59_RS02310 (450169) | 450169..450546 | + | 378 | WP_002382844.1 | hypothetical protein | - |
| I8F59_RS02315 (450598) | 450598..451002 | + | 405 | WP_002363076.1 | NusG domain II-containing protein | - |
| I8F59_RS02320 (451196) | 451196..452266 | + | 1071 | WP_002363077.1 | ammonium transporter | - |
| I8F59_RS15310 (452369) | 452369..453070 | + | 702 | WP_002380057.1 | NAD(P)-binding domain-containing protein | - |
| I8F59_RS15315 (453109) | 453109..453501 | + | 393 | WP_250857038.1 | NAD(P)-binding domain-containing protein | - |
| I8F59_RS02330 (453710) | 453710..454669 | - | 960 | WP_002364892.1 | IS30 family transposase IS1062 | Transposase |
| I8F59_RS02335 (454859) | 454859..455323 | + | 465 | WP_002355429.1 | PTS sugar transporter subunit IIA | - |
| I8F59_RS02340 (455316) | 455316..455612 | + | 297 | WP_002307675.1 | PTS sugar transporter subunit IIB | - |
| I8F59_RS02345 (455632) | 455632..456242 | + | 611 | Protein_442 | PTS beta-glucoside transporter subunit IIBC | - |
| I8F59_RS02350 (456242) | 456242..457103 | - | 862 | Protein_443 | MATE family efflux transporter | - |
| I8F59_RS02355 (457385) | 457385..458053 | + | 669 | WP_002334632.1 | 2,3-diphosphoglycerate-dependent phosphoglycerate mutase | - |
| I8F59_RS02360 (458156) | 458156..458422 | + | 267 | WP_002355434.1 | ACT domain-containing protein | - |
| I8F59_RS02365 (458437) | 458437..459780 | + | 1344 | WP_202496546.1 | PFL family protein | - |
| I8F59_RS02370 (459799) | 459799..460311 | + | 513 | WP_002411204.1 | IS630 family transposase ISBs2 | Transposase |
| I8F59_RS02380 (460683) | 460683..461132 | - | 450 | WP_002331389.1 | DIP1984 family protein | - |
| I8F59_RS02385 (461618) | 461618..462286 | + | 669 | WP_002355437.1 | ABC transporter substrate-binding protein | - |
| I8F59_RS15320 (462287) | 462287..462526 | + | 240 | WP_002389738.1 | conjugal transfer protein TraC | - |
| I8F59_RS02390 (462508) | 462508..463467 | - | 960 | WP_000221326.1 | IS30 family transposase IS6770 | Transposase |
| I8F59_RS02395 (463725) | 463725..464444 | + | 720 | WP_002363088.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| I8F59_RS02400 (464446) | 464446..465288 | + | 843 | WP_002364866.1 | hypothetical protein | VF |
| I8F59_RS02405 (465285) | 465285..466235 | + | 951 | WP_002364865.1 | hypothetical protein | VF |
| I8F59_RS02410 (466250) | 466250..466483 | + | 234 | WP_002297302.1 | iron-dependent repressor | - |
| I8F59_RS02415 (466812) | 466812..467396 | + | 585 | WP_071623368.1 | TetR/AcrR family transcriptional regulator | - |
| I8F59_RS02420 (467527) | 467527..468195 | + | 669 | WP_010729908.1 | energy-coupling factor transporter transmembrane component T | - |
| I8F59_RS02425 (468206) | 468206..469621 | + | 1416 | WP_010706716.1 | energy-coupling factor ABC transporter ATP-binding protein | - |
| I8F59_RS02430 (469639) | 469639..470208 | + | 570 | WP_002363093.1 | MptD family putative ECF transporter S component | - |
| I8F59_RS02435 (470318) | 470318..472072 | + | 1755 | WP_002363094.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| I8F59_RS02440 (472032) | 472032..473798 | + | 1767 | WP_002384861.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| I8F59_RS02445 (474321) | 474321..474581 | + | 261 | WP_002363096.1 | 30S ribosomal protein S14 | - |
| I8F59_RS02450 (474596) | 474596..474775 | + | 180 | WP_002297318.1 | 50S ribosomal protein L32 | - |
| I8F59_RS02455 (474806) | 474806..475183 | + | 378 | WP_002363097.1 | hypothetical protein | - |
| I8F59_RS02460 (475204) | 475204..475353 | + | 150 | WP_002363099.1 | 50S ribosomal protein L33 | - |
| I8F59_RS02465 (475377) | 475377..475532 | + | 156 | Protein_466 | GTP-binding protein | - |
| I8F59_RS15325 (475880) | 475880..476326 | + | 447 | WP_002367954.1 | hypothetical protein | - |
| I8F59_RS02470 (476351) | 476351..477439 | + | 1089 | WP_002364859.1 | hypothetical protein | VF |
| I8F59_RS02475 (477571) | 477571..478142 | + | 572 | Protein_469 | ZinT/AdcA family metal-binding protein | - |
| I8F59_RS02480 (478202) | 478202..478630 | + | 429 | WP_002363103.1 | NusG domain II-containing protein | - |
| I8F59_RS02485 (479016) | 479016..479975 | + | 960 | WP_000221326.1 | IS30 family transposase IS6770 | Transposase |
| I8F59_RS02490 (480365) | 480365..480583 | - | 219 | WP_002363105.1 | hypothetical protein | - |
| I8F59_RS02495 (481105) | 481105..482085 | - | 981 | WP_002363108.1 | ornithine cyclodeaminase family protein | - |
| I8F59_RS02500 (482098) | 482098..482976 | - | 879 | WP_002381227.1 | sulfite exporter TauE/SafE family protein | - |
| I8F59_RS02505 (482992) | 482992..483792 | - | 801 | WP_002406701.1 | helix-turn-helix domain-containing protein | - |
| I8F59_RS02510 (484069) | 484069..484218 | - | 150 | WP_002363111.1 | hypothetical protein | - |
| I8F59_RS02515 (484779) | 484779..484949 | + | 171 | WP_002384869.1 | hypothetical protein | - |
| I8F59_RS15330 (485117) | 485117..485840 | + | 724 | Protein_478 | PTS system mannose/fructose/sorbose family transporter subunit IID | - |
| I8F59_RS02530 (485970) | 485970..486596 | + | 627 | WP_002363114.1 | heparinase II/III family protein | - |
| I8F59_RS15335 (486940) | 486940..487149 | + | 210 | WP_021732829.1 | heparinase II/III family protein | - |
| I8F59_RS02540 (487152) | 487152..487274 | + | 123 | WP_002414819.1 | hypothetical protein | - |
| I8F59_RS02545 (487758) | 487758..488717 | + | 960 | WP_000221326.1 | IS30 family transposase IS6770 | Transposase |
| I8F59_RS02550 (489340) | 489340..490179 | + | 840 | WP_002361212.1 | aldo/keto reductase | - |
| I8F59_RS02555 (490202) | 490202..490684 | + | 483 | WP_002355441.1 | VOC family protein | - |
| I8F59_RS02560 (490850) | 490850..492295 | + | 1446 | WP_002361214.1 | cardiolipin synthase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|