NZ_CP0655291..215857

MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 215857 bp
Accession: NZ_CP065529        Location: 1..215857         Organism: Enterococcus faecium strain VRE3382       Replicon: plasmid unnamed1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISU53_RS14120 () 526..1437 - 912 WP_002289655.1 carbohydrate ABC transporter permease -
ISU53_RS14125 () 1449..2387 - 939 WP_002304874.1 sugar ABC transporter permease -
ISU53_RS14130 () 2616..4190 + 1575 WP_002340467.1 histidine kinase -
ISU53_RS14135 () 4168..4896 + 729 WP_002302980.1 helix-turn-helix domain-containing protein -
ISU53_RS14140 () 5279..6553 - 1275 WP_002340466.1 ISL3 family transposase IS1476 Transposase
ISU53_RS14145 () 6776..7807 - 1032 WP_002302261.1 Vitamin B12 import ATP-binding protein BtuD VF
ISU53_RS14150 () 7814..8644 - 831 WP_002304872.1 hypothetical protein -
ISU53_RS14155 () 8641..9456 - 816 WP_002317023.1 ABC transporter permease subunit -
ISU53_RS14160 () 9453..10277 - 825 WP_002302267.1 alkaline phosphatase family protein -
ISU53_RS14165 () 10267..11367 - 1101 WP_002302268.1 extracellular solute-binding protein -
ISU53_RS14170 () 11545..12330 + 786 WP_002302270.1 histidinol phosphate phosphatase -
ISU53_RS14175 () 12363..12746 + 384 WP_002317021.1 hypothetical protein -
ISU53_RS14180 () 12822..12953 + 132 WP_077828694.1 peptidylprolyl isomerase -
ISU53_RS14185 () 12922..13158 + 237 WP_002322470.1 hypothetical protein VF
ISU53_RS14190 () 13236..14207 - 972 WP_002302275.1 radical SAM protein -
ISU53_RS14195 () 14396..15308 + 913 Protein_16 IS982 family transposase -
ISU53_RS14200 () 15911..17533 + 1623 Protein_17 IS1182 family transposase -
ISU53_RS14205 () 17816..19112 + 1297 Protein_18 ISL3 family transposase ISEfa5 Transposase
ISU53_RS14210 () 19292..20164 - 873 WP_085802747.1 ROK family protein -
ISU53_RS14215 () 20392..21352 - 961 Protein_20 IS30 family transposase IS1062 Transposase
ISU53_RS14220 () 21415..22280 - 866 Protein_21 glycoside hydrolase family 125 protein -
ISU53_RS14225 () 22318..22749 - 432 WP_002389917.1 GNAT family N-acetyltransferase -
ISU53_RS14230 () 22772..23926 - 1155 WP_002389916.1 hypothetical protein VF
ISU53_RS14235 () 23948..25864 - 1917 WP_002389915.1 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) -
ISU53_RS14240 () 25857..26834 - 978 WP_002389914.1 5-dehydro-2-deoxygluconokinase -
ISU53_RS14245 () 26884..27702 - 819 WP_085802703.1 5-deoxy-glucuronate isomerase -
ISU53_RS14250 () 27777..29144 - 1368 WP_002389911.1 C1 family peptidase -
ISU53_RS14255 () 29113..32202 - 3090 WP_085802704.1 alpha-mannosidase -
ISU53_RS14260 () 32245..33201 - 957 Protein_29 IS30 family transposase -
ISU53_RS14265 () 33267..33896 - 630 WP_115250364.1 YitT family protein -
ISU53_RS14270 () 33906..35141 - 1236 WP_002389903.1 PTS sugar transporter subunit IIC -
ISU53_RS14275 () 35154..35489 - 336 WP_002389902.1 PTS sugar transporter subunit IIB -
ISU53_RS14280 () 35491..35802 - 312 WP_174784052.1 PTS lactose/cellobiose transporter subunit IIA -
ISU53_RS14285 () 35804..37813 - 2010 WP_085802706.1 PTS sugar transporter subunit IIA -
ISU53_RS14290 () 37813..38403 - 591 WP_085802707.1 hypothetical protein -
ISU53_RS14295 () 38739..39026 + 288 WP_085802708.1 IS110 family transposase ISAzo28 Transposase
ISU53_RS14300 () 39139..39963 - 825 WP_085802709.1 carbohydrate ABC transporter permease -
ISU53_RS14305 () 39966..40871 - 906 WP_052302011.1 sugar ABC transporter permease -
ISU53_RS14310 () 40972..42225 - 1254 WP_085802710.1 ABC transporter substrate-binding protein -
ISU53_RS14315 () 42242..42979 - 738 WP_044051678.1 sugar phosphate isomerase/epimerase -
ISU53_RS14320 () 43012..43959 - 948 WP_002389891.1 aldo/keto reductase -
ISU53_RS14325 () 44140..45006 + 867 WP_161972993.1 metallophosphoesterase family protein -
ISU53_RS14330 () 45176..45604 - 429 WP_002389889.1 hypothetical protein -
ISU53_RS14335 () 45623..46087 - 465 WP_032494909.1 hypothetical protein -
ISU53_RS14340 () 46161..46469 - 309 WP_002389887.1 hypothetical protein -
ISU53_RS14345 () 46494..46745 - 252 WP_085802711.1 hypothetical protein -
ISU53_RS14350 () 46738..47193 - 456 WP_134789278.1 hypothetical protein -
ISU53_RS14355 () 47344..47571 - 228 WP_014748816.1 hypothetical protein -
ISU53_RS14360 () 47669..47881 - 213 WP_014748817.1 hypothetical protein -
ISU53_RS14365 () 48533..49858 - 1326 WP_032494907.1 PcfJ domain-containing protein -
ISU53_RS14370 () 49864..50631 - 768 WP_044051673.1 hypothetical protein -
ISU53_RS14375 () 51319..51588 - 270 WP_002389879.1 type II toxin-antitoxin system RelE/ParE family toxin -
ISU53_RS14380 () 51578..51844 - 267 WP_014748823.1 antitoxin -
ISU53_RS14385 () 51913..52200 - 288 WP_085802712.1 ADP-ribosylglycohydrolase family protein -
ISU53_RS14390 () 52179..52862 - 684 WP_085802713.1 IS6 family transposase IS1216E Transposase
ISU53_RS14395 () 53438..54130 - 693 WP_002301588.1 MurR/RpiR family transcriptional regulator -
ISU53_RS14400 () 54171..54788 + 618 WP_002309706.1 hypothetical protein -
ISU53_RS14405 () 54924..56173 - 1250 Protein_58 IS110 family transposase ISSpn10 Transposase
ISU53_RS14410 () 56582..57883 + 1302 WP_197667084.1 PTS transporter subunit EIIC -
ISU53_RS14415 () 58282..59472 + 1191 WP_002288791.1 IS256 family transposase ISEf1 Transposase
ISU53_RS14420 () 59641..60063 + 423 WP_002288787.1 hypothetical protein -
ISU53_RS14425 () 60073..60276 + 204 WP_002299573.1 hypothetical protein -
ISU53_RS14430 () 60617..61231 + 615 WP_002298870.1 Tn3 family transposase TnpR_TnAs2 Transposase
ISU53_RS14435 () 61255..61605 - 351 WP_002321032.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin Detail
ISU53_RS14440 () 61599..61862 - 264 WP_002287514.1 hypothetical protein Antitoxin Detail
ISU53_RS14445 () 62203..62382 - 180 WP_002298867.1 hypothetical protein -
ISU53_RS14450 () 62827..63264 - 438 WP_002287515.1 hypothetical protein -
ISU53_RS14455 () 63280..63531 - 252 WP_002287517.1 hypothetical protein -
ISU53_RS14460 () 63531..63737 - 207 WP_014748825.1 hypothetical protein -
ISU53_RS14465 () 64180..64440 - 261 WP_014748826.1 hypothetical protein -
ISU53_RS14470 () 64595..64717 + 123 WP_002295624.1 putative holin-like toxin -
ISU53_RS14475 () 64876..65109 - 234 WP_077495153.1 hypothetical protein -
ISU53_RS14480 () 65154..65639 - 486 WP_002287518.1 single-stranded DNA-binding protein -
ISU53_RS14485 () 65642..66541 - 900 WP_002287519.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
ISU53_RS14490 () 66557..67150 - 594 WP_002287520.1 transcriptional regulator -
ISU53_RS14495 () 67266..68042 - 777 Protein_76 DNA topoisomerase III -
ISU53_RS14500 () 68053..69513 - 1461 WP_002287529.1 toprim domain-containing protein -
ISU53_RS14505 () 69574..71946 - 2373 WP_085806099.1 hypothetical protein -
ISU53_RS14510 () 72356..73607 + 1252 Protein_79 IS110 family transposase ISSpn10 Transposase
ISU53_RS14515 () 73743..73937 - 195 WP_002302840.1 hypothetical protein -
ISU53_RS14520 () 74084..74419 - 336 Protein_81 hypothetical protein -
ISU53_RS14525 () 74431..76023 - 1593 WP_085806008.1 hypothetical protein Relaxase
ISU53_RS14530 () 76043..76465 - 423 WP_085802700.1 hypothetical protein -
ISU53_RS14535 () 76507..76782 - 276 WP_197667085.1 hypothetical protein -
ISU53_RS14540 () 77545..78417 - 873 WP_025479525.1 hypothetical protein -
ISU53_RS14545 () 78681..78911 - 231 WP_002304981.1 hypothetical protein -
ISU53_RS14550 () 78934..79740 - 807 WP_060799048.1 hypothetical protein -
ISU53_RS14555 () 79751..80395 - 645 WP_002390087.1 hypothetical protein -
ISU53_RS14560 () 80411..81616 - 1206 WP_023043274.1 glucosaminidase domain-containing protein -
ISU53_RS14565 () 81616..83640 - 2025 WP_085806010.1 ATPase -
ISU53_RS14570 () 83803..84396 - 594 WP_002343434.1 hypothetical protein -
ISU53_RS14575 () 84397..84729 - 333 WP_085802698.1 hypothetical protein -
ISU53_RS14580 () 84823..85293 - 471 Protein_93 hypothetical protein -
ISU53_RS14585 () 85354..87714 - 2361 WP_085802696.1 hypothetical protein -
ISU53_RS14590 () 87711..90320 - 2610 WP_085806012.1 type IV secretory system conjugative DNA transfer family protein -
ISU53_RS14595 () 90320..92383 - 2064 WP_002390102.1 hypothetical protein -
ISU53_RS14600 () 92453..92755 - 303 WP_002295662.1 hypothetical protein -
ISU53_RS14605 () 92773..93015 - 243 WP_002305229.1 DUF5415 family protein -
ISU53_RS14610 () 93012..93476 - 465 WP_002310966.1 hypothetical protein -
ISU53_RS14615 () 93503..95593 - 2091 WP_060805016.1 isopeptide-forming domain-containing fimbrial protein -
ISU53_RS14620 () 95590..95850 - 261 WP_002302867.1 hypothetical protein -
ISU53_RS14625 () 95863..96624 - 762 WP_060805017.1 hypothetical protein -
ISU53_RS14630 () 96640..97392 - 753 WP_085806014.1 hypothetical protein VF
ISU53_RS14635 () 97407..99383 - 1977 WP_002317432.1 isopeptide-forming domain-containing fimbrial protein -
ISU53_RS14640 () 99436..100110 - 675 WP_002317433.1 class A sortase -
ISU53_RS14645 () 100188..101350 - 1163 Protein_106 EpaQ family protein -
ISU53_RS14650 () 101356..102045 - 690 WP_002317435.1 sortase -
ISU53_RS14655 () 102172..102366 - 195 WP_002293481.1 hypothetical protein -
ISU53_RS14660 () 102476..102715 - 240 WP_002317436.1 hypothetical protein -
ISU53_RS14665 () 102882..103223 - 342 Protein_110 DUF5406 domain-containing protein -
ISU53_RS14670 () 103842..104174 - 333 WP_002322486.1 hypothetical protein -
ISU53_RS14675 () 104998..106038 - 1041 WP_002295675.1 replication initiator protein A -
ISU53_RS14680 () 107203..107289 + 87 Protein_113 single-stranded DNA-binding protein -
ISU53_RS14685 () 107447..108743 - 1297 Protein_114 ISL3 family transposase -
ISU53_RS14690 () 109361..109579 + 219 Protein_115 type II toxin-antitoxin system RelE/ParE family toxin -
ISU53_RS14695 () 109839..110093 + 255 WP_002290397.1 AbrB family transcriptional regulator -
ISU53_RS14700 () 110094..110411 + 318 WP_002290394.1 type II toxin-antitoxin system RelE/ParE family toxin -
ISU53_RS14705 () 110924..111604 + 681 Protein_118 IS6 family transposase IS1216E Transposase
ISU53_RS14710 () 111777..112106 + 330 WP_002292678.1 AbrB family transcriptional regulator -
ISU53_RS14715 () 112096..112383 + 288 WP_002300557.1 type II toxin-antitoxin system RelE/ParE family toxin -
ISU53_RS14720 () 112669..113526 + 858 WP_002292680.1 AAA family ATPase -
ISU53_RS14725 () 113527..114075 + 549 WP_002292681.1 hypothetical protein -
ISU53_RS14730 () 114248..114928 - 681 WP_197667081.1 IS6 family transposase IS1216E Transposase
ISU53_RS14735 () 115676..116374 - 699 WP_002317374.1 GntR family transcriptional regulator -
ISU53_RS14740 () 116358..117092 - 735 WP_002301687.1 GntR family transcriptional regulator -
ISU53_RS14745 () 117309..118322 + 1014 WP_002301686.1 SIS domain-containing protein -
ISU53_RS14750 () 118333..118743 + 411 WP_002301685.1 PTS fructose transporter subunit IIA -
ISU53_RS14755 () 118743..119210 + 468 WP_002301684.1 PTS sugar transporter subunit IIB -
ISU53_RS14760 () 119228..119974 + 747 WP_002301683.1 PTS sugar transporter subunit IIC -
ISU53_RS14765 () 119974..120783 + 810 WP_002301682.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
ISU53_RS14770 () 121344..122017 - 674 Protein_131 IS6 family transposase IS1216V Transposase
ISU53_RS14775 () 122406..124250 + 1845 WP_002289583.1 beta-glucoside-specific PTS transporter subunit IIABC -
ISU53_RS14780 () 124306..125772 + 1467 WP_002289584.1 glycoside hydrolase family 1 protein -
ISU53_RS14785 () 125809..126651 + 843 WP_002289586.1 PRD domain-containing protein -
ISU53_RS14790 () 126868..128163 - 1296 WP_002343827.1 ISL3 family transposase IS1251 Transposase
ISU53_RS14795 () 128442..129896 + 1455 WP_002311502.1 PTS transporter subunit EIIC -
ISU53_RS14800 () 129978..130643 + 666 Protein_137 IS30 family transposase IS1062 Transposase
ISU53_RS14805 () 130740..131699 + 960 WP_002343829.1 IS30 family transposase IS6770 Transposase
ISU53_RS14810 () 131696..132574 + 879 WP_002343830.1 hypothetical protein -
ISU53_RS14815 () 133879..134482 + 604 Protein_140 IS30 family transposase IS6770 Transposase
ISU53_RS14820 () 134534..135712 - 1179 WP_060854031.1 IS256 family transposase ISEf1 Transposase
ISU53_RS14825 () 135832..136080 + 249 WP_002292290.1 GlsB/YeaQ/YmgE family stress response membrane protein -
ISU53_RS14830 () 136280..136684 + 405 WP_002292291.1 organic hydroperoxide resistance protein -
ISU53_RS14835 () 136832..137875 + 1044 WP_002292292.1 hypothetical protein -
ISU53_RS14840 () 137890..138453 + 564 WP_002301446.1 restriction endonuclease subunit S -
ISU53_RS14845 () 138770..139279 + 510 WP_002294762.1 DUF1456 family protein -
ISU53_RS14850 () 139379..140029 + 651 WP_002311759.1 hypothetical protein -
ISU53_RS14855 () 140141..141094 - 954 WP_002343814.1 IS30 family transposase IS1252 Transposase
ISU53_RS14860 () 141279..141578 + 300 WP_002317381.1 hypothetical protein -
ISU53_RS14865 () 142180..142785 + 606 WP_002311756.1 Fic family protein -
ISU53_RS14870 () 143207..144115 - 909 WP_010706260.1 IS982 family transposase ISEfm1 Transposase
ISU53_RS14875 () 144612..145166 + 555 WP_002301108.1 tyrosine-type recombinase/integrase -
ISU53_RS14880 () 145415..145820 + 406 Protein_153 IS200-IS605 family transposase ISEfa4 Transposase
ISU53_RS14885 () 145837..146984 + 1148 Protein_154 IS200-IS605 family transposase ISEfa4 Transposase
ISU53_RS14890 () 147224..147829 + 606 Protein_155 hypothetical protein -
ISU53_RS14895 () 147816..148775 - 960 WP_060806690.1 IS30 family transposase IS1062 Transposase
ISU53_RS14900 () 149409..149624 - 216 Protein_157 IS256 family transposase ISEf1 Transposase
ISU53_RS14910 () 151167..151708 + 542 Protein_159 hypothetical protein -
ISU53_RS14915 () 151864..152238 + 375 WP_002322515.1 TlpA family protein disulfide reductase -
ISU53_RS14925 () 153583..153738 + 156 Protein_162 4Fe-4S binding protein -
ISU53_RS14930 () 153757..155033 + 1277 Protein_163 ABC transporter permease -
ISU53_RS14935 () 155043..155699 + 657 WP_002298083.1 putative ABC transporter ATP-binding protein VF
ISU53_RS14940 () 155699..157075 + 1377 WP_002298085.1 ABC transporter permease -
ISU53_RS14945 () 157385..157579 + 195 WP_002285758.1 hypothetical protein -
ISU53_RS14950 () 157569..157922 + 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
ISU53_RS14955 () 158024..159572 + 1549 Protein_168 IS66 family transposase -
ISU53_RS14960 () 160002..161970 + 1969 Protein_169 hypothetical protein -
ISU53_RS14965 () 161973..162623 + 651 WP_014748775.1 Macrolide export ATP-binding/permease protein MacB VF
ISU53_RS14970 () 163083..163685 - 603 Protein_171 transposase -
ISU53_RS14975 () 163811..165106 + 1296 WP_115250351.1 ISL3 family transposase ISEfa5 Transposase
ISU53_RS14980 () 165280..165404 + 125 Protein_173 IS256 family transposase -
ISU53_RS14985 () 165475..166251 - 777 WP_002390209.1 sulfite exporter TauE/SafE family protein -
ISU53_RS14990 () 166248..167360 - 1113 WP_002390206.1 SPASM domain-containing protein -
ISU53_RS14995 () 167441..168145 - 705 WP_025186461.1 GntR family transcriptional regulator -
ISU53_RS15000 () 168265..170043 + 1779 WP_002364115.1 beta-galactosidase -
ISU53_RS15005 () 170047..170526 + 480 WP_002364114.1 PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB -
ISU53_RS15010 () 170549..170956 + 408 WP_002390204.1 PTS fructose transporter subunit IIA -
ISU53_RS15015 () 171207..171524 + 318 WP_002390202.1 hypothetical protein -
ISU53_RS15020 () 171546..172358 + 813 WP_002364110.1 PTS sugar transporter subunit IIC -
ISU53_RS15025 () 172345..173160 + 816 WP_002390201.1 PTS system mannose/fructose/sorbose family transporter subunit IID -
ISU53_RS15030 () 173479..174936 + 1458 WP_010818874.1 Arylsulfatase VF
ISU53_RS15035 () 176350..177303 - 954 Protein_184 IS30 family transposase -
ISU53_RS15040 () 177400..177483 - 84 Protein_185 addiction module antitoxin -
ISU53_RS15045 () 177832..178917 + 1086 WP_002301591.1 tyrosine recombinase XerS -
ISU53_RS15050 () 179024..179978 - 955 Protein_187 IS30 family transposase IS1252 Transposase
ISU53_RS15055 () 180197..181447 - 1251 WP_002330944.1 PTS sugar transporter subunit IIC -
ISU53_RS15060 () 181466..182392 - 927 WP_002298736.1 PEP phosphonomutase -
ISU53_RS15065 () 182471..183466 - 996 WP_002301128.1 tagatose-bisphosphate aldolase -
ISU53_RS15070 () 183482..184651 - 1170 WP_002301130.1 SIS domain-containing protein -
ISU53_RS15075 () 184667..185401 - 735 WP_002301131.1 GntR family transcriptional regulator -
ISU53_RS15080 () 185920..187212 - 1293 Protein_193 IS256 family transposase ISBsu2 Transposase
ISU53_RS15085 () 187313..188863 - 1551 Protein_194 IS66 family transposase ISRob1 Transposase
ISU53_RS15090 () 188935..189315 - 381 WP_197667082.1 IS66 family transposase ISDeal1 Transposase
ISU53_RS15095 () 189305..189499 - 195 WP_002285758.1 hypothetical protein -
ISU53_RS15100 () 189658..190538 - 881 Protein_197 IS3 family transposase ISEfa8 Transposase
ISU53_RS15105 () 190740..191135 - 396 WP_002287876.1 aspartate 1-decarboxylase -
ISU53_RS15110 () 191145..191993 - 849 WP_002287875.1 pantoate--beta-alanine ligase -
ISU53_RS15115 () 192008..192835 - 828 WP_002287874.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
ISU53_RS15120 () 192901..193706 - 806 Protein_201 DUF2520 domain-containing protein -
ISU53_RS15125 () 193943..194860 + 918 Protein_202 IS256 family transposase ISEfa13 Transposase
ISU53_RS15130 () 194938..196485 - 1548 Protein_203 IS66 family transposase ISCde1 Transposase
ISU53_RS15135 () 196587..196939 - 353 Protein_204 IS66 family transposase ISEbi1 Transposase
ISU53_RS15140 () 196929..197123 - 195 WP_002285758.1 hypothetical protein -
ISU53_RS15145 () 197511..197915 + 405 WP_002287522.1 IS200-IS605 family transposase ISEfa4 Transposase
ISU53_RS15150 () 197932..199080 + 1149 Protein_207 IS200-IS605 family transposase ISEfa4 Transposase
ISU53_RS15155 () 199355..199591 - 237 WP_014748793.1 hypothetical protein -
ISU53_RS15160 () 199770..200948 + 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
ISU53_RS15165 () 201052..202359 - 1308 Protein_210 HAMP domain-containing histidine kinase -
ISU53_RS15170 () 202356..203009 - 654 WP_002285815.1 Transcriptional regulatory protein QseB VF
ISU53_RS15175 () 203297..204571 + 1275 WP_085806033.1 ISL3 family transposase IS1476 Transposase
ISU53_RS15180 () 204626..206191 + 1566 WP_032494987.1 glutamine-hydrolyzing GMP synthase -
ISU53_RS15185 () 206551..207483 - 933 WP_002288609.1 hypothetical protein -
ISU53_RS15190 () 207523..209184 - 1662 WP_002288608.1 O-GlcNAcase NagJ VF
ISU53_RS15195 () 209181..212162 - 2982 WP_002305865.1 glycoside hydrolase family 42 -
ISU53_RS15200 () 212290..214203 - 1914 WP_002304880.1 beta-N-acetylhexosaminidase -
ISU53_RS15205 () 214233..214844 - 612 WP_002304878.1 DUF624 domain-containing protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance