MGE detailed information
MGE type: Conjugative plasmid MGE length: 168672 bp
Accession: NZ_CP064175 Location: 1..168672 Organism: Klebsiella pneumoniae strain 19110124 Replicon: plasmid p19110124-1
Accession: NZ_CP064175 Location: 1..168672 Organism: Klebsiella pneumoniae strain 19110124 Replicon: plasmid p19110124-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ISU39_RS26105 () | 1..1011 | + | 1011 | WP_004182030.1 | RepB family plasmid replication initiator protein | - |
| ISU39_RS26110 () | 1729..2469 | - | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| ISU39_RS26115 () | 3613..4560 | + | 948 | WP_004182028.1 | sensor domain-containing diguanylate cyclase | - |
| ISU39_RS26120 () | 4587..4898 | - | 312 | WP_071527918.1 | EAL domain-containing protein | - |
| ISU39_RS26125 () | 4918..5886 | + | 969 | WP_068814619.1 | IS5 family transposase IS903B | Transposase |
| ISU39_RS26130 () | 6559..6816 | - | 258 | WP_004197688.1 | hypothetical protein | - |
| ISU39_RS26135 () | 7436..8872 | + | 1437 | WP_080895248.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| ISU39_RS26140 () | 9855..11132 | - | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| ISU39_RS26145 () | 11195..13192 | - | 1998 | WP_064152327.1 | choline BCCT transporter BetT | - |
| ISU39_RS26150 () | 13344..14041 | - | 698 | Protein_9 | IS1 family transposase IS1X2 | Transposase |
| ISU39_RS26160 () | 15530..16014 | + | 485 | Protein_11 | IS1 family transposase IS1X2 | Transposase |
| ISU39_RS26165 () | 16030..16572 | + | 543 | Protein_12 | ISL3 family transposase ISKpn25 | Transposase |
| ISU39_RS26170 () | 16868..17299 | - | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| ISU39_RS26175 () | 17550..19025 | - | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| ISU39_RS26180 () | 19018..19698 | - | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| ISU39_RS26185 () | 19888..21273 | + | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| ISU39_RS26190 () | 21302..21655 | + | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| ISU39_RS26195 () | 21769..23061 | + | 1293 | WP_004098959.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| ISU39_RS26200 () | 23072..26218 | + | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| ISU39_RS26205 () | 26305..26745 | + | 441 | WP_000758228.1 | hypothetical protein | - |
| ISU39_RS26210 () | 26872..29319 | + | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| ISU39_RS26215 () | 29360..29557 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| ISU39_RS26220 () | 29591..30328 | - | 738 | WP_004182013.1 | Murein DD-endopeptidase MepM | VF |
| ISU39_RS26225 () | 30617..31066 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| ISU39_RS26230 () | 31300..33117 | + | 1818 | WP_064152319.1 | multicopper oxidase PcoA | - |
| ISU39_RS26235 () | 33123..34013 | + | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| ISU39_RS26240 () | 34053..34433 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| ISU39_RS26245 () | 34438..35367 | + | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| ISU39_RS26250 () | 35422..36102 | + | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| ISU39_RS26255 () | 36099..37499 | + | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| ISU39_RS26260 () | 37716..38150 | + | 435 | WP_004152085.1 | copper resistance system metallochaperone PcoE | - |
| ISU39_RS26265 () | 38382..38561 | - | 180 | WP_024623170.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| ISU39_RS26270 () | 38622..40242 | - | 1621 | Protein_33 | ISL3 family transposase ISEc38 | Transposase |
| ISU39_RS26275 () | 40304..40813 | + | 510 | WP_004196769.1 | aquaporin | - |
| ISU39_RS26280 () | 40863..41360 | - | 498 | WP_004196778.1 | GNAT family N-acetyltransferase | - |
| ISU39_RS26285 () | 41692..42018 | + | 327 | WP_004152092.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| ISU39_RS26290 () | 42015..42728 | + | 714 | WP_004182006.1 | arsenical resistance protein ArsH | - |
| ISU39_RS26295 () | 42737..43282 | + | 546 | WP_004182005.1 | sigma-70 family RNA polymerase sigma factor | - |
| ISU39_RS26300 () | 43358..43720 | + | 363 | WP_004152095.1 | arsenic metallochaperone ArsD family protein | - |
| ISU39_RS26305 () | 43745..45495 | + | 1751 | Protein_40 | arsenical pump-driving ATPase | - |
| ISU39_RS26310 () | 45617..46153 | + | 537 | WP_004152096.1 | GNAT family N-acetyltransferase | - |
| ISU39_RS26315 () | 46186..46611 | - | 426 | WP_004152097.1 | glutaredoxin-dependent arsenate reductase | - |
| ISU39_RS26320 () | 46624..47913 | - | 1290 | WP_004152098.1 | arsenite efflux transporter membrane subunit ArsB | - |
| ISU39_RS26325 () | 47961..49712 | - | 1752 | WP_100774790.1 | Arsenical pump-driving ATPase | VF |
| ISU39_RS26330 () | 49730..50092 | - | 363 | WP_004152100.1 | arsenite efflux transporter metallochaperone ArsD | - |
| ISU39_RS26335 () | 50142..50492 | - | 351 | WP_004152101.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| ISU39_RS26340 () | 50850..51119 | + | 270 | WP_004152102.1 | hypothetical protein | - |
| ISU39_RS26345 () | 51107..51682 | + | 576 | WP_004152103.1 | hypothetical protein | - |
| ISU39_RS26350 () | 51713..52207 | + | 495 | WP_100774791.1 | DNA-binding protein | - |
| ISU39_RS26355 () | 52251..52619 | + | 369 | WP_004152105.1 | hypothetical protein | - |
| ISU39_RS26360 () | 52653..52856 | + | 204 | WP_004152106.1 | hemolysin expression modulator Hha | - |
| ISU39_RS26365 () | 52905..53162 | + | 258 | WP_004152107.1 | hypothetical protein | - |
| ISU39_RS26370 () | 53238..53492 | + | 255 | WP_004152108.1 | hypothetical protein | - |
| ISU39_RS26375 () | 53668..53934 | + | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| ISU39_RS26380 () | 53922..54404 | + | 483 | WP_003026803.1 | GNAT family N-acetyltransferase | Toxin Detail |
| ISU39_RS26385 () | 54605..56008 | + | 1404 | WP_001567368.1 | ISNCY family transposase ISKpn21 | Transposase |
| ISU39_RS26390 () | 56037..56669 | - | 633 | WP_001567369.1 | hypothetical protein | - |
| ISU39_RS26395 () | 56883..57089 | + | 207 | Protein_58 | ISNCY family transposase ISLad2 | Transposase |
| ISU39_RS26400 () | 57287..59050 | + | 1764 | WP_004200842.1 | DUF262 domain-containing protein | - |
| ISU39_RS26405 () | 59700..60563 | - | 864 | WP_004200841.1 | toll/interleukin-1 receptor domain-containing protein | - |
| ISU39_RS26410 () | 60580..61005 | - | 426 | WP_077255340.1 | hypothetical protein | - |
| ISU39_RS26415 () | 61917..62801 | + | 885 | WP_017896188.1 | hypothetical protein | - |
| ISU39_RS26420 () | 63411..63959 | - | 549 | WP_004200838.1 | thioredoxin fold domain-containing protein | - |
| ISU39_RS26425 () | 64467..65462 | + | 996 | WP_004200837.1 | IS110 family transposase IS1663 | Transposase |
| ISU39_RS26430 () | 65700..66668 | - | 969 | WP_004200835.1 | phage exclusion protein | - |
| ISU39_RS26435 () | 67197..69506 | + | 2310 | WP_000421673.1 | TerB N-terminal domain-containing protein | - |
| ISU39_RS26440 () | 69510..70826 | + | 1317 | WP_004152291.1 | ATP-binding protein | - |
| ISU39_RS26445 () | 70823..73018 | + | 2196 | WP_004200832.1 | DEAD/DEAH box helicase | - |
| ISU39_RS26450 () | 74345..74773 | - | 429 | WP_004200827.1 | hypothetical protein | - |
| ISU39_RS26455 () | 74783..75067 | - | 285 | WP_004200826.1 | hypothetical protein | - |
| ISU39_RS26460 () | 76378..77391 | - | 1014 | WP_016831068.1 | hypothetical protein | - |
| ISU39_RS26465 () | 77550..77621 | - | 72 | WP_071786674.1 | RepA leader peptide Tap | - |
| ISU39_RS26470 () | 77833..78102 | - | 270 | WP_016831067.1 | replication regulatory protein RepA | - |
| ISU39_RS26475 () | 78238..78717 | - | 480 | WP_069346050.1 | Phospholipase D | VF |
| ISU39_RS26480 () | 78893..79201 | - | 309 | WP_016831065.1 | hypothetical protein | - |
| ISU39_RS26485 () | 79198..79848 | - | 651 | WP_016831064.1 | DUF2726 domain-containing protein | - |
| ISU39_RS26490 () | 79904..80125 | - | 222 | WP_016831063.1 | hypothetical protein | - |
| ISU39_RS26495 () | 80595..80941 | - | 347 | Protein_78 | hypothetical protein | - |
| ISU39_RS26500 () | 80961..81557 | - | 597 | WP_016831061.1 | fertility inhibition protein FinO | - |
| ISU39_RS26505 () | 81629..82354 | - | 726 | WP_016831060.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| ISU39_RS26510 () | 82435..87693 | - | 5259 | WP_016831059.1 | Multifunctional conjugation protein TraI | Relaxase |
| ISU39_RS26515 () | 87693..89975 | - | 2283 | Protein_82 | type IV conjugative transfer system coupling protein TraD | - |
| ISU39_RS26520 () | 90102..90791 | - | 690 | WP_186483393.1 | hypothetical protein | - |
| ISU39_RS26525 () | 90984..91715 | - | 732 | WP_016831056.1 | complement resistance protein TraT | - |
| ISU39_RS26530 () | 91966..92568 | - | 603 | WP_071604857.1 | hypothetical protein | - |
| ISU39_RS26535 () | 92591..95413 | - | 2823 | WP_016831055.1 | conjugal transfer mating pair stabilization protein TraG | - |
| ISU39_RS26540 () | 95413..96792 | - | 1380 | WP_072159542.1 | conjugal transfer protein TraH | - |
| ISU39_RS26545 () | 96770..97213 | - | 444 | WP_016831053.1 | F-type conjugal transfer protein TrbF | - |
| ISU39_RS26550 () | 97259..97816 | - | 558 | WP_004152678.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| ISU39_RS26555 () | 97788..98027 | - | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| ISU39_RS26560 () | 98038..98790 | - | 753 | WP_064152311.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| ISU39_RS26565 () | 98811..99137 | - | 327 | WP_016831051.1 | hypothetical protein | - |
| ISU39_RS26570 () | 99150..99398 | - | 249 | WP_004152675.1 | hypothetical protein | - |
| ISU39_RS26575 () | 99376..99630 | - | 255 | WP_015065558.1 | conjugal transfer protein TrbE | - |
| ISU39_RS26580 () | 99662..101617 | - | 1956 | WP_023313940.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| ISU39_RS26585 () | 101676..102323 | - | 648 | WP_016831049.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| ISU39_RS26590 () | 102402..102578 | - | 177 | WP_162866177.1 | hypothetical protein | - |
| ISU39_RS26595 () | 102599..103588 | - | 990 | WP_015632509.1 | conjugal transfer pilus assembly protein TraU | - |
| ISU39_RS26600 () | 103585..103986 | - | 402 | WP_016831047.1 | hypothetical protein | - |
| ISU39_RS26605 () | 104021..104656 | - | 636 | WP_016831046.1 | type-F conjugative transfer system protein TraW | - |
| ISU39_RS26610 () | 104656..105045 | - | 390 | WP_004167468.1 | type-F conjugative transfer system protein TrbI | - |
| ISU39_RS26615 () | 105045..107684 | - | 2640 | WP_016831045.1 | type IV secretion system protein TraC | - |
| ISU39_RS26620 () | 107756..108154 | - | 399 | WP_074182648.1 | hypothetical protein | - |
| ISU39_RS26625 () | 108162..108552 | - | 391 | Protein_104 | hypothetical protein | - |
| ISU39_RS26630 () | 108595..108999 | - | 405 | WP_016831042.1 | hypothetical protein | - |
| ISU39_RS26635 () | 109066..109377 | - | 312 | WP_016831041.1 | hypothetical protein | - |
| ISU39_RS26640 () | 109378..109596 | - | 219 | WP_014386199.1 | hypothetical protein | - |
| ISU39_RS26645 () | 109620..109909 | - | 290 | Protein_108 | hypothetical protein | - |
| ISU39_RS26650 () | 109914..110324 | - | 411 | WP_032409654.1 | hypothetical protein | - |
| ISU39_RS26655 () | 110456..111040 | - | 585 | WP_014386196.1 | type IV conjugative transfer system lipoprotein TraV | - |
| ISU39_RS26660 () | 111063..111659 | - | 597 | Protein_111 | conjugal transfer protein TraP | - |
| ISU39_RS26665 () | 111652..113076 | - | 1425 | WP_016831036.1 | conjugal transfer protein TraB | - |
| ISU39_RS26670 () | 113076..113816 | - | 741 | WP_014386193.1 | type-F conjugative transfer system secretin TraK | - |
| ISU39_RS26675 () | 113803..114369 | - | 567 | WP_016831035.1 | type IV conjugative transfer system protein TraE | - |
| ISU39_RS26680 () | 114389..114694 | - | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| ISU39_RS26685 () | 114708..115076 | - | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| ISU39_RS26690 () | 115138..115344 | - | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| ISU39_RS26695 () | 115477..116196 | - | 720 | WP_016831034.1 | conjugal transfer protein TrbJ | - |
| ISU39_RS26700 () | 116396..116812 | - | 417 | WP_072145360.1 | relaxosome protein TraM | - |
| ISU39_RS26705 () | 117203..117688 | + | 486 | WP_004178063.1 | hypothetical protein | VF |
| ISU39_RS26710 () | 117721..118050 | - | 330 | WP_011977736.1 | hypothetical protein | - |
| ISU39_RS26715 () | 118083..118904 | - | 822 | WP_004182076.1 | DUF945 domain-containing protein | - |
| ISU39_RS26720 () | 119737..119910 | - | 174 | WP_194636508.1 | helix-turn-helix domain-containing protein | - |
| ISU39_RS26725 () | 120175..121179 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| ISU39_RS26730 () | 121407..122612 | + | 1206 | WP_065726122.1 | chromate efflux transporter | - |
| ISU39_RS26735 () | 122623..122928 | + | 306 | WP_000130000.1 | hypothetical protein | Relaxase |
| ISU39_RS26740 () | 122972..123037 | + | 66 | Protein_127 | EAL domain-containing protein | - |
| ISU39_RS26745 () | 123155..123919 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| ISU39_RS26750 () | 124412..124996 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| ISU39_RS26755 () | 124996..126234 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| ISU39_RS26760 () | 126231..127136 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| ISU39_RS26765 () | 127258..127962 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ISU39_RS26770 () | 128113..128928 | + | 816 | WP_000018329.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| ISU39_RS26775 () | 129118..129822 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ISU39_RS26780 () | 129887..131137 | - | 1251 | Protein_135 | transposase | - |
| ISU39_RS26785 () | 131212..131880 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| ISU39_RS26790 () | 131916..132152 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| ISU39_RS26795 () | 132149..132511 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| ISU39_RS26800 () | 132529..134223 | - | 1695 | WP_100774810.1 | mercury(II) reductase | - |
| ISU39_RS26805 () | 134275..134697 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| ISU39_RS26810 () | 134733..135008 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| ISU39_RS26815 () | 135022..135372 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| ISU39_RS26820 () | 135444..135878 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| ISU39_RS26825 () | 135957..136961 | + | 1005 | WP_000427623.1 | IS110 family transposase IS4321R | Transposase |
| ISU39_RS26830 () | 137239..137496 | - | 258 | Protein_145 | transcriptional regulator | - |
| ISU39_RS26835 () | 137497..137775 | - | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| ISU39_RS26840 () | 137765..138085 | - | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| ISU39_RS26845 () | 138166..138390 | - | 225 | WP_004152719.1 | hypothetical protein | - |
| ISU39_RS26850 () | 138401..138613 | - | 213 | WP_004182070.1 | hypothetical protein | - |
| ISU39_RS26855 () | 138674..139030 | - | 357 | WP_004152717.1 | hypothetical protein | - |
| ISU39_RS26860 () | 139666..140016 | - | 351 | WP_004182068.1 | hypothetical protein | - |
| ISU39_RS26865 () | 140013..140285 | - | 273 | WP_004182067.1 | hypothetical protein | - |
| ISU39_RS26870 () | 140981..141142 | - | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| ISU39_RS26875 () | 141212..142291 | + | 1080 | WP_009653230.1 | IS481 family transposase ISKpn28 | Transposase |
| ISU39_RS26880 () | 142469..142843 | - | 375 | WP_004182064.1 | hypothetical protein | - |
| ISU39_RS26885 () | 142899..143225 | - | 327 | WP_004152639.1 | hypothetical protein | - |
| ISU39_RS26890 () | 143222..143950 | - | 729 | WP_004152640.1 | plasmid SOS inhibition protein A | - |
| ISU39_RS26895 () | 143947..144378 | - | 432 | WP_004182061.1 | conjugation system SOS inhibitor PsiB | - |
| ISU39_RS26900 () | 144423..146480 | - | 2058 | WP_004182059.1 | ParB/RepB/Spo0J family partition protein | - |
| ISU39_RS26905 () | 146550..146798 | - | 249 | WP_004182058.1 | DUF905 domain-containing protein | - |
| ISU39_RS26910 () | 146847..147389 | - | 543 | WP_004182056.1 | single-stranded DNA-binding protein | - |
| ISU39_RS26915 () | 148224..148787 | - | 564 | WP_004182054.1 | methyltransferase | - |
| ISU39_RS26920 () | 148835..150190 | - | 1356 | WP_004182052.1 | DUF3560 domain-containing protein | - |
| ISU39_RS26925 () | 150242..150472 | - | 231 | WP_001568051.1 | hypothetical protein | - |
| ISU39_RS26930 () | 150564..150791 | - | 228 | WP_004182050.1 | hypothetical protein | - |
| ISU39_RS26935 () | 151518..151835 | - | 318 | WP_004118473.1 | hypothetical protein | - |
| ISU39_RS26940 () | 151870..152124 | - | 255 | WP_004152754.1 | DNA polymerase III subunit theta | - |
| ISU39_RS26945 () | 152361..152786 | - | 426 | WP_004118478.1 | antirestriction protein | - |
| ISU39_RS26950 () | 153306..153536 | - | 231 | WP_004118481.1 | hypothetical protein | - |
| ISU39_RS26955 () | 153770..155281 | - | 1512 | WP_024623221.1 | Group II intron-encoded protein LtrA | VF |
| ISU39_RS26960 () | 155683..156108 | + | 426 | WP_004182047.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| ISU39_RS26965 () | 156108..157380 | + | 1273 | Protein_172 | Y-family DNA polymerase | - |
| ISU39_RS26970 () | 157459..157710 | + | 252 | WP_004182043.1 | hypothetical protein | - |
| ISU39_RS26975 () | 157955..159907 | - | 1953 | WP_000037308.1 | DUF262 domain-containing HNH endonuclease family protein | - |
| ISU39_RS26980 () | 159904..161184 | - | 1281 | WP_004182042.1 | DUF262 domain-containing protein | - |
| ISU39_RS26985 () | 162152..162847 | + | 696 | Protein_176 | IS1 family transposase IS1A | Transposase |
| ISU39_RS26990 () | 163625..164741 | - | 1117 | Protein_177 | IS3 family transposase ISSen4 | Transposase |
| ISU39_RS26995 () | 165784..166755 | - | 972 | WP_004182039.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| ISU39_RS27000 () | 166755..167921 | - | 1167 | WP_004182032.1 | Sporulation initiation inhibitor protein Soj | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|