MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 131081 bp
Accession: NZ_CP063879 Location: 1..131081 Organism: Klebsiella pneumoniae strain M169-3 Replicon: plasmid pM169-3.1
Accession: NZ_CP063879 Location: 1..131081 Organism: Klebsiella pneumoniae strain M169-3 Replicon: plasmid pM169-3.1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ISB47_RS27045 | 2783..2857 | - | 75 | WP_227642738.1 | helix-turn-helix domain-containing protein | - |
| ISB47_RS27050 | 3072..4334 | + | 1263 | WP_000608644.1 | IS1380 family transposase ISEcp1 | Transposase |
| ISB47_RS27055 | 4590..5465 | + | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| ISB47_RS27060 | 5512..5856 | - | 345 | Protein_4 | WbuC family cupin fold metalloprotein | - |
| ISB47_RS27065 | 5870..8089 | + | 2220 | Protein_5 | Tn3 family transposase TnpA_Tn3 | Transposase |
| ISB47_RS27070 | 8166..8870 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ISB47_RS27075 | 8924..9364 | - | 441 | Protein_7 | CatB-related O-acetyltransferase | - |
| ISB47_RS27080 | 9502..10330 | - | 829 | Protein_8 | Beta-lactamase OXA-1 | ARG |
| ISB47_RS27085 | 10461..11015 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| ISB47_RS27090 | 11159..11856 | - | 698 | Protein_10 | IS6 family transposase IS15DII | Transposase |
| ISB47_RS27095 | 11922..13436 | + | 1515 | Protein_11 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| ISB47_RS27100 | 13478..13720 | + | 243 | WP_032140899.1 | hypothetical protein | - |
| ISB47_RS27105 | 13752..14402 | - | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| ISB47_RS27110 | 14508..15707 | + | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| ISB47_RS27115 | 15739..16623 | - | 885 | WP_000058717.1 | EamA family transporter | - |
| ISB47_RS27120 | 16761..17153 | - | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| ISB47_RS27125 | 17157..17906 | + | 750 | Protein_17 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| ISB47_RS27130 | 17930..18145 | - | 216 | Protein_18 | helix-turn-helix domain-containing protein | - |
| ISB47_RS27135 | 18197..18901 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ISB47_RS27140 | 19225..19629 | + | 405 | Protein_20 | IS91 family transposase ISPps1 | Transposase |
| ISB47_RS27145 | 19736..20572 | - | 837 | WP_000480972.1 | hypothetical protein | ARG |
| ISB47_RS27150 | 20572..21375 | - | 804 | WP_001082320.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| ISB47_RS27155 | 21436..22251 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| ISB47_RS27160 | 22578..22664 | + | 87 | Protein_24 | Arm DNA-binding domain-containing protein | - |
| ISB47_RS27165 | 22936..23940 | - | 1005 | WP_237085623.1 | IS110 family transposase IS5075 | Transposase |
| ISB47_RS27170 | 24019..25980 | - | 1962 | Protein_26 | Tn3 family transposase TnpA_ISPa38 | Transposase |
| ISB47_RS27175 | 26041..26745 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ISB47_RS27180 | 26889..27442 | + | 554 | Protein_28 | AAC(6')-Ib family aminoglycoside 6'-N-acetyltransferase | - |
| ISB47_RS27185 | 27573..28403 | + | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| ISB47_RS27190 | 28541..28981 | + | 441 | Protein_30 | CatB-related O-acetyltransferase | - |
| ISB47_RS27195 | 29035..29740 | - | 706 | Protein_31 | IS6 family transposase IS15DI | Transposase |
| ISB47_RS27200 | 29817..32027 | - | 2211 | Protein_32 | Tn3 family transposase TnpA_Tn3 | Transposase |
| ISB47_RS27205 | 32041..32385 | + | 345 | Protein_33 | WbuC family cupin fold metalloprotein | - |
| ISB47_RS27210 | 32428..33301 | - | 874 | Protein_34 | Beta-lactamase CTX-M-1 | ARG |
| ISB47_RS27215 | 33557..34815 | - | 1259 | Protein_35 | IS1380 family transposase ISEcp1 | Transposase |
| ISB47_RS27220 | 35030..35104 | + | 75 | WP_227642738.1 | helix-turn-helix domain-containing protein | - |
| ISB47_RS27225 | 36390..36518 | - | 129 | WP_237085626.1 | SEC-C metal-binding domain-containing protein | - |
| ISB47_RS27230 | 36515..37252 | - | 738 | WP_237085624.1 | hypothetical protein | - |
| ISB47_RS27235 | 37447..37920 | - | 474 | WP_237085625.1 | hypothetical protein | - |
| ISB47_RS27240 | 39579..39746 | - | 168 | Protein_40 | RepB family plasmid replication initiator protein | - |
| ISB47_RS27245 | 39862..40566 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| ISB47_RS27250 | 40631..40999 | + | 369 | Protein_42 | Tn3 family transposase TnpR_ISSba14 | Transposase |
| ISB47_RS27255 | 41186..41743 | + | 558 | WP_032445547.1 | OsmC family protein | - |
| ISB47_RS27260 | 41885..42466 | + | 582 | WP_008502230.1 | HTH-type transcriptional repressor NemR | VF |
| ISB47_RS27265 | 42471..42809 | + | 339 | WP_000888080.1 | carboxymuconolactone decarboxylase family protein | - |
| ISB47_RS27270 | 42839..43168 | - | 330 | WP_008502229.1 | thioredoxin family protein | - |
| ISB47_RS27275 | 43381..44487 | + | 1107 | WP_006687059.1 | alkene reductase | - |
| ISB47_RS27280 | 44553..45254 | + | 702 | WP_008502228.1 | DsbA family oxidoreductase | - |
| ISB47_RS27285 | 45320..46093 | + | 774 | WP_001091224.1 | SDR family oxidoreductase | - |
| ISB47_RS27290 | 46279..47502 | - | 1224 | WP_000872613.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| ISB47_RS27295 | 47633..48463 | - | 831 | WP_020324597.1 | DMT family transporter | - |
| ISB47_RS27300 | 48705..49457 | + | 753 | WP_020324592.1 | alpha/beta hydrolase | - |
| ISB47_RS27305 | 49484..49797 | + | 314 | Protein_53 | Tn3 family transposase | - |
| ISB47_RS27310 | 49953..50246 | + | 294 | Protein_54 | ArsA-related P-loop ATPase | - |
| ISB47_RS27315 | 50277..50702 | - | 426 | WP_000065758.1 | glutaredoxin-dependent arsenate reductase | - |
| ISB47_RS27320 | 50715..52004 | - | 1290 | WP_000922630.1 | arsenite efflux transporter membrane subunit ArsB | - |
| ISB47_RS27325 | 52053..53804 | - | 1752 | WP_001556710.1 | arsenite efflux transporter ATPase subunit ArsA | - |
| ISB47_RS27330 | 53822..54184 | - | 363 | WP_020324593.1 | arsenite efflux transporter metallochaperone ArsD | - |
| ISB47_RS27335 | 54232..54585 | - | 354 | WP_001114073.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| ISB47_RS27340 | 54878..55018 | + | 141 | WP_004118614.1 | hypothetical protein | - |
| ISB47_RS27345 | 55186..55494 | + | 309 | WP_020324596.1 | Ref family recombination enhancement nuclease | - |
| ISB47_RS27350 | 55918..56577 | + | 660 | WP_000078540.1 | hypothetical protein | - |
| ISB47_RS27355 | 56574..56903 | + | 330 | WP_004118613.1 | hypothetical protein | - |
| ISB47_RS27360 | 56896..58098 | + | 1203 | WP_003031541.1 | hypothetical protein | - |
| ISB47_RS27365 | 58135..58554 | - | 420 | WP_000990392.1 | helix-turn-helix domain-containing protein | Antitoxin Detail |
| ISB47_RS27370 | 58551..58862 | - | 312 | WP_004118600.1 | type II toxin-antitoxin system HigB family toxin | Toxin Detail |
| ISB47_RS27375 | 59073..59453 | + | 381 | Protein_67 | gluconate permease | - |
| ISB47_RS27380 | 59503..60198 | - | 696 | WP_004118595.1 | lactate utilization protein C | - |
| ISB47_RS27385 | 60191..61618 | - | 1428 | WP_000023895.1 | LutB/LldF family L-lactate oxidation iron-sulfur protein | - |
| ISB47_RS27390 | 61629..62348 | - | 720 | WP_001102107.1 | (Fe-S)-binding protein | - |
| ISB47_RS27395 | 62423..64120 | - | 1698 | WP_020324177.1 | D-lactate dehydrogenase | - |
| ISB47_RS27400 | 64556..66109 | + | 1554 | WP_020324174.1 | L-lactate permease | - |
| ISB47_RS27410 | 67801..68004 | - | 204 | WP_004150739.1 | HHA domain-containing protein | - |
| ISB47_RS27415 | 68065..68559 | - | 495 | WP_004213594.1 | hypothetical protein | - |
| ISB47_RS27420 | 68590..69156 | - | 567 | WP_009310052.1 | hypothetical protein | - |
| ISB47_RS27425 | 69153..69416 | - | 264 | WP_009310051.1 | hypothetical protein | - |
| ISB47_RS27430 | 69729..69908 | + | 180 | WP_004118349.1 | type II toxin-antitoxin system ParD family antitoxin | - |
| ISB47_RS27435 | 69895..69993 | + | 99 | WP_032445197.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| ISB47_RS27440 | 70030..70192 | + | 163 | Protein_80 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| ISB47_RS27445 | 70372..70806 | - | 435 | WP_004118347.1 | hypothetical protein | - |
| ISB47_RS27450 | 71022..72422 | - | 1401 | WP_002436614.1 | copper resistance membrane spanning protein PcoS | - |
| ISB47_RS27455 | 72419..73099 | - | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| ISB47_RS27460 | 73154..74083 | - | 930 | WP_004118344.1 | copper resistance inner membrane protein PcoD | - |
| ISB47_RS27465 | 74088..74468 | - | 381 | WP_001549790.1 | copper resistance system metallochaperone PcoC | - |
| ISB47_RS27470 | 74508..75398 | - | 891 | WP_001378118.1 | copper resistance outer membrane transporter PcoB | - |
| ISB47_RS27475 | 75404..77221 | - | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| ISB47_RS27480 | 77455..77904 | + | 450 | WP_001023257.1 | copper resistance protein | - |
| ISB47_RS27485 | 78193..78930 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| ISB47_RS27490 | 78964..79161 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| ISB47_RS27495 | 79202..81649 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| ISB47_RS27500 | 81776..82216 | - | 441 | WP_000758228.1 | DUF411 domain-containing protein | - |
| ISB47_RS27505 | 82303..85449 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| ISB47_RS27510 | 85460..86752 | - | 1293 | WP_004098959.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| ISB47_RS27515 | 86866..87219 | - | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| ISB47_RS27520 | 87248..88633 | - | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| ISB47_RS27525 | 88823..89503 | + | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| ISB47_RS27530 | 89496..90971 | + | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| ISB47_RS27535 | 91222..91653 | + | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| ISB47_RS27540 | 91949..92491 | - | 543 | Protein_100 | ISL3 family transposase ISKpn25 | Transposase |
| ISB47_RS27545 | 92507..92991 | - | 485 | Protein_101 | IS1 family transposase IS1X2 | Transposase |
| ISB47_RS27550 | 93082..94289 | + | 1208 | WP_087530333.1 | IS3 family transposase ISEcl1 | Transposase |
| ISB47_RS27555 | 94480..95177 | + | 698 | WP_223174975.1 | IS1 family transposase IS1X2 | Transposase |
| ISB47_RS27560 | 95329..97326 | + | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| ISB47_RS27565 | 97389..98666 | + | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| ISB47_RS27570 | 99649..100485 | - | 837 | WP_004178087.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| ISB47_RS27575 | 100549..101064 | - | 516 | Protein_107 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| ISB47_RS27580 | 101706..101963 | + | 258 | WP_004197688.1 | hypothetical protein | - |
| ISB47_RS27585 | 102636..103604 | - | 969 | WP_068814619.1 | IS5 family transposase IS903B | Transposase |
| ISB47_RS27590 | 103693..103935 | + | 243 | WP_074428705.1 | EAL domain-containing protein | - |
| ISB47_RS27595 | 103962..104909 | - | 948 | WP_004182028.1 | sensor domain-containing diguanylate cyclase | - |
| ISB47_RS27600 | 106053..106793 | + | 741 | WP_020324066.1 | tyrosine-type recombinase/integrase | - |
| ISB47_RS27605 | 107511..108521 | - | 1011 | WP_004182030.1 | RepB family plasmid replication initiator protein | - |
| ISB47_RS27610 | 109273..110439 | + | 1167 | WP_004182032.1 | Sporulation initiation inhibitor protein Soj | VF |
| ISB47_RS27615 | 110439..111410 | + | 972 | WP_004182039.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| ISB47_RS27620 | 112453..113572 | + | 1120 | Protein_116 | IS3 family transposase ISSen4 | Transposase |
| ISB47_RS27625 | 114347..115042 | - | 696 | Protein_117 | IS1 family transposase | - |
| ISB47_RS27630 | 115084..115500 | + | 417 | WP_023157785.1 | hypothetical protein | - |
| ISB47_RS27635 | 116010..116741 | + | 732 | Protein_119 | DUF262 domain-containing protein | - |
| ISB47_RS27640 | 116806..117509 | + | 704 | Protein_120 | IS6 family transposase IS15DII | Transposase |
| ISB47_RS27645 | 117563..118366 | + | 804 | Protein_121 | Multifunctional conjugation protein TraI | Relaxase |
| ISB47_RS27650 | 118447..119172 | + | 726 | WP_016831060.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| ISB47_RS27655 | 119244..119840 | + | 597 | WP_016831061.1 | fertility inhibition protein FinO | - |
| ISB47_RS27660 | 119860..120207 | + | 348 | Protein_124 | DUF6404 family protein | - |
| ISB47_RS27665 | 120677..120898 | + | 222 | WP_029497438.1 | hypothetical protein | - |
| ISB47_RS27670 | 120954..121604 | + | 651 | WP_029498344.1 | DUF2726 domain-containing protein | - |
| ISB47_RS27675 | 121601..121909 | + | 309 | WP_016831065.1 | hypothetical protein | - |
| ISB47_RS27680 | 122013..122564 | + | 552 | WP_029498342.1 | Phospholipase D | VF |
| ISB47_RS27685 | 122700..122969 | + | 270 | WP_016831067.1 | replication regulatory protein RepA | - |
| ISB47_RS28050 | 123181..123252 | + | 72 | WP_071786674.1 | RepA leader peptide Tap | - |
| ISB47_RS27700 | 123411..124424 | + | 1014 | WP_016831068.1 | plasmid replication initiator RepA | - |
| ISB47_RS27705 | 125412..125738 | - | 327 | WP_004201125.1 | C2H2-type zinc finger protein | - |
| ISB47_RS27710 | 125920..126201 | + | 282 | WP_001568067.1 | hypothetical protein | - |
| ISB47_RS27715 | 126255..126866 | + | 612 | WP_000176305.1 | DUF2913 family protein | - |
| ISB47_RS27720 | 126863..126994 | - | 132 | Protein_135 | hypothetical protein | VF |
| ISB47_RS27725 | 127051..128043 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| ISB47_RS27730 | 128092..128247 | - | 156 | WP_000075580.1 | hypothetical protein | - |
| ISB47_RS27735 | 128388..129089 | + | 702 | Protein_138 | IS6 family transposase IS15DII | Transposase |
| ISB47_RS27740 | 129205..129372 | + | 168 | Protein_139 | RepB family plasmid replication initiator protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|