MGE detailed information
MGE type: Conjugative plasmid MGE length: 107554 bp
Accession: NZ_CP063761 Location: 1..107554 Organism: Klebsiella pneumoniae strain FRPDR Replicon: plasmid pFRPDR_KPC
Accession: NZ_CP063761 Location: 1..107554 Organism: Klebsiella pneumoniae strain FRPDR Replicon: plasmid pFRPDR_KPC
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IM727_RS28680 () | 1..858 | + | 858 | WP_032495102.1 | incFII family plasmid replication initiator RepA | - |
| IM727_RS28685 () | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| IM727_RS28690 () | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| IM727_RS28695 () | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| IM727_RS28700 () | 3383..3798 | + | 416 | Protein_5 | IS1 family transposase | - |
| IM727_RS28705 () | 3834..4379 | - | 546 | Protein_6 | Tn3 family transposase TnpA_Tn3 | Transposase |
| IM727_RS28710 () | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IM727_RS28715 () | 5219..5410 | + | 192 | Protein_8 | transposase | - |
| IM727_RS28720 () | 5660..6535 | + | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| IM727_RS28725 () | 6570..7538 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| IM727_RS28730 () | 7595..8692 | + | 1098 | Protein_11 | TonB-dependent receptor | - |
| IM727_RS28735 () | 8760..9209 | - | 450 | Protein_12 | PAS domain-containing protein | - |
| IM727_RS28740 () | 9289..9993 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IM727_RS28745 () | 10058..10648 | + | 591 | Protein_14 | IS91 family transposase ISSbo1 | Transposase |
| IM727_RS28750 () | 11104..11808 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IM727_RS28755 () | 11859..12476 | - | 618 | Protein_16 | IS91 family transposase ISSbo1 | Transposase |
| IM727_RS28760 () | 12486..12674 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| IM727_RS28765 () | 12766..13302 | + | 537 | WP_064441864.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| IM727_RS28770 () | 13485..14345 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| IM727_RS28775 () | 14515..15270 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| IM727_RS28780 () | 15351..15632 | - | 282 | WP_015059004.1 | sodium/hydrogen exchanger | - |
| IM727_RS28785 () | 15720..16424 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IM727_RS28790 () | 16415..16555 | + | 141 | WP_071557810.1 | hypothetical protein | - |
| IM727_RS28795 () | 17549..18553 | - | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| IM727_RS28800 () | 19331..19565 | + | 235 | Protein_25 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| IM727_RS28805 () | 19693..19974 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| IM727_RS28810 () | 20097..20447 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| IM727_RS28815 () | 20450..21412 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| IM727_RS28820 () | 21559..21852 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| IM727_RS28825 () | 21929..22612 | + | 684 | WP_000085883.1 | DNA methylase | - |
| IM727_RS28830 () | 22613..22834 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| IM727_RS28835 () | 22848..23282 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| IM727_RS28840 () | 23333..24109 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| IM727_RS28845 () | 24527..24952 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| IM727_RS28850 () | 24999..25421 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| IM727_RS28855 () | 25418..25609 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| IM727_RS28860 () | 25923..27590 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| IM727_RS28865 () | 28990..29220 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| IM727_RS28870 () | 29272..30633 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| IM727_RS28875 () | 30680..31243 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| IM727_RS28880 () | 32092..32619 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| IM727_RS28885 () | 32677..32910 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| IM727_RS28890 () | 32971..34994 | + | 2024 | Protein_43 | ParB/RepB/Spo0J family partition protein | - |
| IM727_RS28895 () | 35063..35497 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| IM727_RS28900 () | 35494..36213 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 36225..36449 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 36225..36449 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 36225..36449 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 36225..36449 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| IM727_RS28905 () | 36493..36651 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| IM727_RS28910 () | 36889..37266 | - | 378 | Protein_47 | hypothetical protein | - |
| IM727_RS28915 () | 37566..37862 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| IM727_RS28920 () | 37973..38794 | + | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| IM727_RS28925 () | 39091..39738 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| IM727_RS28930 () | 40015..40398 | + | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| IM727_RS28935 () | 40589..41275 | + | 687 | WP_015059009.1 | PAS domain-containing protein | - |
| IM727_RS28940 () | 41369..41596 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| IM727_RS28945 () | 41630..41995 | + | 366 | WP_021519752.1 | type IV conjugative transfer system pilin TraA | - |
| IM727_RS28950 () | 42010..42321 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| IM727_RS28955 () | 42343..42909 | + | 567 | WP_000399794.1 | type IV conjugative transfer system protein TraE | - |
| IM727_RS28960 () | 42920..43624 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| IM727_RS28965 () | 43624..45051 | + | 1428 | WP_032297072.1 | conjugal transfer protein TraB | - |
| IM727_RS28970 () | 45041..45631 | + | 591 | WP_000002778.1 | conjugal transfer protein TraP | - |
| IM727_RS28975 () | 45585..45815 | + | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| IM727_RS28980 () | 45827..46078 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| IM727_RS28985 () | 46075..46590 | + | 516 | WP_062955122.1 | type IV conjugative transfer system lipoprotein TraV | - |
| IM727_RS28990 () | 46725..46946 | + | 222 | WP_001278692.1 | conjugal transfer protein TraR | - |
| IM727_RS28995 () | 47106..49733 | + | 2628 | WP_015059012.1 | type IV secretion system protein TraC | - |
| IM727_RS29000 () | 49730..50116 | + | 387 | WP_015059013.1 | type-F conjugative transfer system protein TrbI | - |
| IM727_RS29005 () | 50113..50745 | + | 633 | WP_001203735.1 | type-F conjugative transfer system protein TraW | - |
| IM727_RS29010 () | 50742..51734 | + | 993 | WP_000830838.1 | conjugal transfer pilus assembly protein TraU | - |
| IM727_RS29015 () | 51761..52069 | + | 309 | WP_000412447.1 | hypothetical protein | - |
| IM727_RS29020 () | 52132..52653 | + | 522 | WP_015059014.1 | hypothetical protein | - |
| IM727_RS29025 () | 52680..53318 | + | 639 | WP_000087532.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| IM727_RS29030 () | 53315..53686 | + | 372 | WP_000056336.1 | hypothetical protein | - |
| IM727_RS29035 () | 53712..54134 | + | 423 | WP_001229309.1 | HNH endonuclease | - |
| IM727_RS29040 () | 54131..55981 | + | 1851 | WP_015059015.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| IM727_RS29045 () | 56008..56265 | + | 258 | WP_053913405.1 | conjugal transfer protein TrbE | - |
| IM727_RS29050 () | 56252..57001 | + | 750 | WP_072354014.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| IM727_RS29055 () | 57117..57398 | + | 282 | WP_000549793.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| IM727_RS29060 () | 57385..57930 | + | 546 | WP_000059817.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| IM727_RS29065 () | 57860..58234 | + | 375 | WP_071776752.1 | P-type conjugative transfer protein TrbJ | - |
| IM727_RS29070 () | 58188..58580 | + | 393 | WP_000126338.1 | F-type conjugal transfer protein TrbF | - |
| IM727_RS29075 () | 58567..59940 | + | 1374 | WP_000944325.1 | conjugal transfer protein TraH | - |
| IM727_RS29080 () | 59937..62753 | + | 2817 | WP_015059018.1 | conjugal transfer mating pair stabilization protein TraG | - |
| IM727_RS29085 () | 62786..63307 | + | 522 | WP_000632668.1 | conjugal transfer entry exclusion protein TraS | - |
| IM727_RS29090 () | 63332..64063 | + | 732 | WP_021559024.1 | complement resistance protein TraT | - |
| IM727_RS29095 () | 64266..64589 | + | 324 | WP_194201660.1 | hypothetical protein | - |
| IM727_RS29100 () | 64618..65315 | + | 698 | Protein_85 | IS1 family transposase ISKpn14 | Transposase |
| IM727_RS29105 () | 65366..65779 | + | 414 | WP_194201661.1 | hypothetical protein | - |
| IM727_RS29110 () | 65830..68028 | + | 2199 | WP_011402783.1 | type IV conjugative transfer system coupling protein TraD | - |
| IM727_RS29115 () | 68028..73163 | + | 5136 | WP_071177725.1 | Multifunctional conjugation protein TraI | Relaxase |
| IM727_RS29120 () | 73197..73901 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IM727_RS29125 () | 73965..74240 | + | 276 | Protein_90 | PAS domain-containing protein | - |
| IM727_RS29130 () | 74304..75008 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IM727_RS29135 () | 75062..75385 | - | 324 | Protein_92 | class II aldolase/adducin family protein | - |
| IM727_RS29140 () | 75378..76630 | - | 1253 | Protein_93 | four-carbon acid sugar kinase family protein | - |
| IM727_RS29145 () | 76642..77544 | - | 903 | WP_004151610.1 | NAD(P)-dependent oxidoreductase | - |
| IM727_RS29150 () | 77806..78567 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| IM727_RS29155 () | 78588..79448 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| IM727_RS29160 () | 79585..79653 | + | 69 | Protein_97 | IS6 family transposase | - |
| IM727_RS29165 () | 79689..82655 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| IM727_RS29170 () | 82659..83219 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| IM727_RS29175 () | 83611..84228 | + | 618 | Protein_100 | replication protein | - |
| IM727_RS29180 () | 84762..85040 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| IM727_RS29185 () | 85151..85576 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| IM727_RS29190 () | 85704..85859 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| IM727_RS29195 () | 85905..86201 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| IM727_RS29200 () | 86305..87186 | + | 882 | Protein_105 | IS1182 family transposase ISKpn6 | Transposase |
| IM727_RS29205 () | 87436..88317 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| IM727_RS29210 () | 88593..89573 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| IM727_RS29215 () | 89696..90157 | - | 462 | Protein_108 | Tn3 family transposase TnpR_Tn3 | Transposase |
| IM727_RS29220 () | 90209..90913 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IM727_RS29225 () | 90978..92150 | - | 1173 | Protein_110 | transposase | - |
| IM727_RS29230 () | 92225..92893 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| IM727_RS29235 () | 92929..93165 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| IM727_RS29240 () | 93162..93524 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| IM727_RS29245 () | 93542..95236 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| IM727_RS29250 () | 95288..95710 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| IM727_RS29255 () | 95746..96021 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| IM727_RS29260 () | 96035..96385 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| IM727_RS29265 () | 96457..96891 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| IM727_RS29270 () | 96970..97974 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| IM727_RS29275 () | 98254..98526 | - | 273 | Protein_120 | IS5 family transposase ISPan1 | Transposase |
| IM727_RS29280 () | 98555..99252 | - | 698 | Protein_121 | IS1 family transposase ISKpn14 | Transposase |
| IM727_RS29285 () | 99508..100530 | - | 1023 | WP_000361404.1 | helicase UvrD | - |
| IM727_RS29290 () | 100515..102077 | - | 1563 | WP_004206609.1 | AAA family ATPase | - |
| IM727_RS29295 () | 102236..102940 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| IM727_RS29300 () | 103004..103165 | + | 162 | Protein_125 | DNA helicase | - |
| IM727_RS29305 () | 103185..103931 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| IM727_RS29310 () | 103986..104546 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| IM727_RS29315 () | 104678..104878 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| IM727_RS29320 () | 105264..105863 | + | 600 | WP_032083981.1 | hypothetical protein | - |
| IM727_RS29325 () | 106027..106257 | + | 231 | WP_001736714.1 | hypothetical protein | - |
| - () | 106458..106517 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 106458..106517 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 106458..106517 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 106458..106517 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| IM727_RS29330 () | 106562..106711 | + | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| IM727_RS29335 () | 106995..107243 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|