NZ_CP0618181..213054

MGE detailed information

MGE type: Non-Mobilizable plasmid        MGE length: 213054 bp
Accession: NZ_CP061818        Location: 1..213054         Organism: Enterococcus faecium strain A6521       Replicon: plasmid pA6521_1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HI837_RS13855 () 1..1041 + 1041 WP_002322487.1 replication initiator protein A -
HI837_RS13860 () 1882..2214 + 333 WP_002322486.1 hypothetical protein -
HI837_RS13865 () 2833..3174 + 342 WP_002311521.1 DUF5406 domain-containing protein -
HI837_RS13870 () 3193..3483 + 291 WP_002311523.1 hypothetical protein -
HI837_RS13875 () 3675..3908 + 234 WP_002311524.1 hypothetical protein -
HI837_RS13880 () 4314..4985 + 672 WP_002313095.1 class A sortase -
HI837_RS13885 () 5038..7017 + 1980 WP_060805018.1 isopeptide-forming domain-containing fimbrial protein -
HI837_RS13890 () 7032..7784 + 753 WP_002316053.1 hypothetical protein VF
HI837_RS13895 () 7800..8561 + 762 WP_060805017.1 hypothetical protein -
HI837_RS13900 () 8574..8834 + 261 WP_002302867.1 hypothetical protein -
HI837_RS13905 () 8831..10921 + 2091 WP_060805016.1 isopeptide-forming domain-containing fimbrial protein -
HI837_RS13910 () 10948..11412 + 465 WP_002310966.1 hypothetical protein -
HI837_RS13915 () 11409..11651 + 243 WP_002305229.1 DUF5415 family protein -
HI837_RS13920 () 11669..11971 + 303 WP_002295662.1 hypothetical protein -
HI837_RS13925 () 12041..14104 + 2064 WP_060805015.1 hypothetical protein -
HI837_RS13930 () 14104..16713 + 2610 WP_002340495.1 type IV secretory system conjugative DNA transfer family protein -
HI837_RS13935 () 16710..19106 + 2397 WP_002340494.1 hypothetical protein -
HI837_RS13940 () 19158..19490 + 333 WP_002340493.1 hypothetical protein -
HI837_RS13945 () 19491..20084 + 594 WP_002340492.1 hypothetical protein -
HI837_RS13950 () 20247..22271 + 2025 WP_002340490.1 hypothetical protein -
HI837_RS13955 () 22271..23476 + 1206 WP_002323679.1 glucosaminidase domain-containing protein -
HI837_RS13960 () 23492..24136 + 645 WP_002340489.1 hypothetical protein -
HI837_RS13965 () 24147..24953 + 807 WP_002311549.1 hypothetical protein -
HI837_RS13970 () 24976..25206 + 231 WP_060804943.1 hypothetical protein -
HI837_RS13975 () 25324..26283 + 960 WP_002340487.1 IS30 family transposase IS6770 Transposase
HI837_RS13980 () 26777..27064 + 288 WP_002311551.1 hypothetical protein -
HI837_RS13985 () 27082..27504 + 423 WP_002311552.1 hypothetical protein -
HI837_RS13990 () 27524..29116 + 1593 WP_033583488.1 hypothetical protein Relaxase
HI837_RS13995 () 29372..29566 + 195 WP_002316755.1 hypothetical protein -
HI837_RS14000 () 29702..30952 - 1251 WP_002297404.1 IS110 family transposase ISSpn10 Transposase
HI837_RS14005 () 31362..33734 + 2373 WP_002311557.1 hypothetical protein -
HI837_RS14010 () 33795..35255 + 1461 WP_002353044.1 toprim domain-containing protein -
HI837_RS14015 () 35266..35709 + 444 WP_002353045.1 topoisomerase -
HI837_RS14020 () 35794..37470 + 1677 WP_002340482.1 type IA DNA topoisomerase -
HI837_RS14025 () 37486..37635 + 150 WP_002295632.1 hypothetical protein -
HI837_RS14030 () 37716..38312 + 597 WP_002295629.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
HI837_RS14035 () 38325..39224 + 900 WP_002340481.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
HI837_RS14040 () 39227..39711 + 485 Protein_37 single-stranded DNA-binding protein -
HI837_RS14045 () 39733..39990 + 258 WP_002295625.1 hypothetical protein -
HI837_RS14050 () 40149..40283 - 135 WP_002311565.1 putative holin-like toxin -
HI837_RS14055 () 40426..40686 + 261 WP_002295623.1 hypothetical protein -
HI837_RS14060 () 41135..41341 + 207 WP_002295619.1 hypothetical protein -
HI837_RS14065 () 41341..41592 + 252 WP_002293542.1 hypothetical protein -
HI837_RS14070 () 41608..42045 + 438 WP_002311567.1 hypothetical protein -
HI837_RS14075 () 42481..42651 + 171 WP_002293544.1 hypothetical protein -
HI837_RS14080 () 42726..43121 + 396 WP_002293546.1 hypothetical protein -
HI837_RS14085 () 43103..43369 + 267 WP_002314432.1 hypothetical protein -
HI837_RS14090 () 43379..43612 + 234 WP_002340480.1 DUF2786 domain-containing protein -
HI837_RS14095 () 43982..44941 + 960 WP_002297271.1 IS30 family transposase IS6770 Transposase
HI837_RS14100 () 45002..45205 + 204 WP_002307514.1 leucocin A/sakacin P family class II bacteriocin -
HI837_RS14105 () 45195..45416 + 222 WP_002340479.1 hypothetical protein -
HI837_RS14110 () 45457..46619 + 1163 WP_086956687.1 IS3 family transposase IS1485 Transposase
HI837_RS14115 () 46649..47405 - 757 Protein_52 HAD family hydrolase -
HI837_RS14120 () 47410..48177 - 768 WP_002290556.1 DeoR/GlpR family DNA-binding transcription regulator -
HI837_RS14125 () 48665..49090 + 426 WP_002290555.1 galactose-6-phosphate isomerase subunit LacA -
HI837_RS14130 () 49107..49622 + 516 WP_002290554.1 galactose-6-phosphate isomerase subunit LacB -
HI837_RS14135 () 49633..50565 + 933 WP_002340477.1 tagatose-6-phosphate kinase -
HI837_RS14140 () 50568..51548 + 981 WP_002290551.1 tagatose-bisphosphate aldolase -
HI837_RS14145 () 51576..51893 + 318 WP_002290550.1 PTS lactose/cellobiose transporter subunit IIA -
HI837_RS14150 () 51893..53599 + 1707 WP_002340476.1 lactose-specific PTS transporter subunit EIIC -
HI837_RS14155 () 53741..55147 + 1407 WP_002290548.1 6-phospho-beta-galactosidase -
HI837_RS14160 () 55170..55442 + 273 WP_002305107.1 DUF3884 family protein -
HI837_RS14165 () 55463..56362 + 900 WP_002303235.1 aldose 1-epimerase family protein -
HI837_RS14175 () 58693..59871 + 1179 WP_000997695.1 IS256 family transposase ISEf1 Transposase
HI837_RS14180 () 59996..60904 - 909 WP_002295743.1 IS982 family transposase ISEfm1 Transposase
HI837_RS14185 () 61307..63253 + 1947 WP_002300833.1 PTS sugar transporter subunit IIA -
HI837_RS14190 () 63256..63711 + 456 WP_002300835.1 PTS sugar transporter subunit IIA -
HI837_RS14195 () 63725..65053 + 1329 WP_002300836.1 PTS galactitol transporter subunit IIC -
HI837_RS14200 () 65087..65371 + 285 WP_002300838.1 PTS sugar transporter subunit IIB -
HI837_RS14205 () 65373..65888 + 516 WP_002300840.1 YjbQ family protein -
HI837_RS14210 () 65904..66566 + 663 WP_002300841.1 Ribulose-phosphate 3-epimerase VF
HI837_RS14215 () 66573..67145 + 573 WP_002300842.1 3-hexulose-6-phosphate isomerase VF
HI837_RS14220 () 67332..68852 - 1521 WP_002300843.1 IS66 family transposase ISDeal1 Transposase
HI837_RS14225 () 69095..69280 - 186 WP_002305884.1 IS66 family transposase ISEbi1 Transposase
HI837_RS14230 () 69264..69446 - 183 WP_002300846.1 hypothetical protein -
HI837_RS14235 () 69687..69905 + 219 Protein_76 IS256 family transposase ISLgar5 Transposase
HI837_RS14240 () 70366..70998 + 633 WP_002313151.1 Tyrosine recombinase XerD VF
HI837_RS14245 () 71062..71661 + 600 WP_002322465.1 bacteriophage abortive infection AbiH family protein -
HI837_RS14250 () 71691..72339 - 649 Protein_79 IS6 family transposase IS1216V Transposase
HI837_RS14255 () 72674..73546 - 873 WP_002305879.1 ROK family protein -
HI837_RS14260 () 73810..75756 - 1947 WP_002352509.1 sucrose-specific PTS transporter subunit IIBC -
HI837_RS14265 () 75941..77380 + 1440 WP_002302078.1 sucrose-6-phosphate hydrolase -
HI837_RS14270 () 77382..78344 + 963 WP_002302077.1 LacI family DNA-binding transcriptional regulator -
HI837_RS14275 () 78550..79845 - 1296 WP_002297218.1 ISL3 family transposase ISEfa11 Transposase
HI837_RS14285 () 81705..82160 + 456 WP_002301718.1 IS200-IS605 family transposase ISAac3 Transposase
HI837_RS14290 () 82425..82523 + 99 Protein_87 IS30 family transposase -
HI837_RS14295 () 82746..82976 - 231 WP_002289255.1 resolvase -
HI837_RS14300 () 83206..84024 - 819 WP_002289254.1 MurR/RpiR family transcriptional regulator -
HI837_RS14305 () 84185..84874 + 690 WP_002289253.1 N-acetylmannosamine-6-phosphate 2-epimerase -
HI837_RS14310 () 84888..86390 + 1503 WP_002289252.1 PTS transporter subunit EIIC -
HI837_RS14315 () 86403..86879 + 477 WP_002300328.1 PTS glucose transporter subunit IIA -
HI837_RS14320 () 86976..87086 - 111 Protein_93 transposase -
HI837_RS14330 () 89657..90175 + 519 WP_002287870.1 ClbS/DfsB family four-helix bundle protein -
HI837_RS14335 () 92251..93336 + 1086 WP_002301591.1 tyrosine recombinase XerS -
HI837_RS14340 () 93444..94397 - 954 WP_000222572.1 IS30 family transposase IS1252 Transposase
HI837_RS14345 () 94528..95778 - 1251 WP_002301126.1 PTS sugar transporter subunit IIC -
HI837_RS14350 () 95797..96723 - 927 WP_002298736.1 PEP phosphonomutase -
HI837_RS14355 () 96802..97797 - 996 WP_002301128.1 tagatose-bisphosphate aldolase -
HI837_RS14360 () 97813..98982 - 1170 WP_002301130.1 SIS domain-containing protein -
HI837_RS14365 () 98998..99732 - 735 WP_002301131.1 GntR family transcriptional regulator -
HI837_RS14375 () 101924..103263 + 1340 WP_086953915.1 IS3 family transposase ISEnfa3 Transposase
HI837_RS14380 () 103654..104946 - 1293 WP_002301811.1 IS256 family transposase ISBsu2 Transposase
HI837_RS14385 () 105220..105480 - 261 WP_002313174.1 hypothetical protein -
HI837_RS14390 () 105653..106825 + 1173 WP_000195429.1 IS256 family transposase IS256 Transposase
HI837_RS14395 () 107060..108229 + 1170 WP_002300493.1 IS256 family transposase ISEfa13 Transposase
HI837_RS14400 () 108554..109873 - 1320 WP_002300494.1 HAMP domain-containing histidine kinase -
HI837_RS14405 () 109870..110523 - 654 WP_002285815.1 Transcriptional regulatory protein QseB VF
HI837_RS14410 () 110811..111744 + 934 Protein_111 ISL3 family transposase IS1476 Transposase
HI837_RS14415 () 111652..112368 - 717 WP_002348630.1 aminotransferase class V-fold PLP-dependent enzyme -
HI837_RS14420 () 112418..112627 - 210 WP_002302256.1 hypothetical protein -
HI837_RS14425 () 112904..114177 + 1274 Protein_114 ISL3 family transposase ISEfa11 Transposase
HI837_RS14430 () 114284..115315 - 1032 WP_002302261.1 Spermidine/putrescine import ATP-binding protein PotA VF
HI837_RS14435 () 115322..116152 - 831 WP_002313180.1 ABC transporter permease -
HI837_RS14440 () 116149..116964 - 816 WP_002330693.1 ABC transporter permease subunit -
HI837_RS14445 () 116961..117785 - 825 WP_002302267.1 alkaline phosphatase family protein -
HI837_RS14450 () 117775..118875 - 1101 WP_002302268.1 extracellular solute-binding protein -
HI837_RS14455 () 119053..119838 + 786 WP_002302270.1 histidinol phosphate phosphatase -
HI837_RS14460 () 119871..120254 + 384 WP_002330694.1 hypothetical protein -
HI837_RS14465 () 120330..120461 + 132 WP_077828694.1 peptidylprolyl isomerase -
HI837_RS14470 () 120430..120666 + 237 WP_002322470.1 Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase VF
HI837_RS14475 () 120744..121715 - 972 WP_002302275.1 radical SAM protein -
HI837_RS14480 () 122367..123989 + 1623 WP_002340465.1 IS1182 family transposase ISEfa7 Transposase
HI837_RS14485 () 124275..125651 - 1377 WP_002301195.1 ABC transporter permease -
HI837_RS14490 () 125651..126307 - 657 WP_002298083.1 putative ABC transporter ATP-binding protein VF
HI837_RS14495 () 126317..127594 - 1278 WP_002301194.1 ABC transporter permease -
HI837_RS14500 () 127613..127768 - 156 Protein_129 4Fe-4S binding protein -
HI837_RS14505 () 127844..129006 + 1163 WP_087121905.1 IS3 family transposase ISEfa8 Transposase
HI837_RS14510 () 129036..129485 - 450 WP_002330699.1 TlpA family protein disulfide reductase -
HI837_RS14515 () 129641..130183 - 543 WP_002298088.1 hypothetical protein -
HI837_RS14520 () 130411..131573 + 1163 WP_111994893.1 IS3 family transposase ISEfa8 Transposase
HI837_RS14525 () 131679..131894 + 216 Protein_134 IS256 family transposase ISEf1 Transposase
HI837_RS14530 () 132185..132664 - 480 WP_002340462.1 hypothetical protein -
HI837_RS14535 () 132734..133642 - 909 WP_002295743.1 IS982 family transposase ISEfm1 Transposase
HI837_RS14540 () 133753..134064 - 312 Protein_137 hypothetical protein -
HI837_RS14545 () 134318..134872 - 555 WP_002301108.1 tyrosine-type recombinase/integrase -
HI837_RS14550 () 135337..136290 + 954 WP_127820643.1 IS30 family transposase IS1252 Transposase
HI837_RS14555 () 137335..137946 - 612 WP_010729766.1 IS6 family transposase IS1297 Transposase
HI837_RS14560 () 138007..138603 + 597 WP_002351514.1 Tn3 family transposase TnpR_TnAs1 Transposase
HI837_RS14565 () 138600..139190 - 591 Protein_142 hypothetical protein -
HI837_RS14570 () 139265..140812 - 1548 WP_002296127.1 IS66 family transposase ISRob1 Transposase
HI837_RS14575 () 140914..141267 - 354 WP_002287659.1 IS66 family transposase ISDeal1 Transposase
HI837_RS14580 () 141257..141451 - 195 WP_002285758.1 hypothetical protein -
HI837_RS14585 () 141535..141903 - 369 Protein_146 toll/interleukin-1 receptor domain-containing protein -
HI837_RS14590 () 142407..142916 - 510 WP_191664880.1 hypothetical protein -
HI837_RS14595 () 143072..144250 + 1179 WP_106914365.1 IS256 family transposase ISEfm2 Transposase
HI837_RS14600 () 144289..146085 - 1797 WP_191664881.1 S8 family peptidase -
HI837_RS14605 () 146100..147242 - 1143 WP_080497384.1 ATP-binding protein -
HI837_RS14610 () 147288..148073 - 786 WP_175413409.1 toll/interleukin-1 receptor domain-containing protein -
HI837_RS14615 () 148098..149270 + 1173 WP_000195429.1 IS256 family transposase IS256 Transposase
HI837_RS14620 () 149400..150839 - 1440 WP_001028141.1 Bifunctional AAC/APH ARG
HI837_RS14625 () 150840..151232 - 393 WP_000393259.1 GNAT family N-acetyltransferase -
HI837_RS14630 () 151289..152461 - 1173 WP_000195429.1 IS256 family transposase IS256 Transposase
HI837_RS14635 () 152568..154058 - 1491 WP_002380753.1 primase C-terminal domain-containing protein -
HI837_RS14640 () 154453..154692 - 240 WP_002380754.1 helix-turn-helix domain-containing protein -
HI837_RS14645 () 154936..155109 - 174 WP_171902975.1 rRNA adenine methyltransferase -
HI837_RS14650 () 155054..155791 - 738 WP_001038790.1 rRNA adenine N-6-methyltransferase ARG
HI837_RS14655 () 155916..155981 - 66 Protein_160 23S rRNA methyltransferase attenuation leader peptide -
HI837_RS14660 () 156034..156117 - 84 Protein_161 peptide-binding protein -
HI837_RS14665 () 156661..157524 - 864 WP_002401483.1 zeta toxin family protein Toxin Detail
HI837_RS14670 () 157526..157798 - 273 WP_000301765.1 antitoxin Antitoxin Detail
HI837_RS14675 () 157815..158024 - 210 WP_000527317.1 peptide-binding protein -
HI837_RS14680 () 158101..158997 - 897 WP_118215883.1 ParA family protein -
HI837_RS14685 () 159100..159360 - 261 Protein_166 topoisomerase DNA-binding C4 zinc finger domain-containing protein -
HI837_RS14690 () 159530..160267 - 738 WP_094899423.1 rRNA adenine N-6-methyltransferase ARG
HI837_RS14695 () 160392..160487 - 96 WP_001809736.1 23S rRNA methyltransferase attenuation leader peptide -
HI837_RS14700 () 160536..160775 - 240 WP_000635249.1 peptide-binding protein -
HI837_RS14705 () 160903..163047 - 2145 WP_130006275.1 type IA DNA topoisomerase -
HI837_RS14710 () 163368..163583 - 216 WP_076720021.1 IS481 family transposase ISChy3 Transposase
HI837_RS14715 () 163561..164154 - 594 WP_171970647.1 Tn3 family transposase TnBth3 Transposase
HI837_RS14720 () 164716..165768 - 1053 WP_076720018.1 TIGR00341 family protein -
HI837_RS14725 () 165963..166568 + 606 WP_076720016.1 Tn3 family transposase TnpR_TnAs2 Transposase
HI837_RS14730 () 166597..168477 - 1881 WP_076720015.1 ATP-binding protein -
HI837_RS14735 () 168470..169462 - 993 WP_076720013.1 SIR2 family protein -
HI837_RS14740 () 170183..171304 - 1122 WP_002291076.1 hypothetical protein VF
HI837_RS14745 () 171301..172497 - 1197 WP_076720012.1 hypothetical protein VF
HI837_RS14750 () 172583..174070 - 1488 WP_076720010.1 SpaH/EbpB family LPXTG-anchored major pilin -
HI837_RS14755 () 174135..174866 - 732 WP_076720009.1 hypothetical protein VF
HI837_RS14760 () 174868..178521 - 3654 WP_076720007.1 hypothetical protein VF
HI837_RS14765 () 179304..179984 - 681 WP_002319817.1 IS6 family transposase IS1297 Transposase
HI837_RS14770 () 180250..180798 - 549 WP_002292681.1 hypothetical protein -
HI837_RS14775 () 180799..181656 - 858 WP_002292680.1 AAA family ATPase -
HI837_RS14780 () 181942..182229 - 288 WP_076713767.1 type II toxin-antitoxin system RelE/ParE family toxin -
HI837_RS14785 () 182219..182548 - 330 WP_002292678.1 AbrB family transcriptional regulator -
HI837_RS14790 () 182721..183401 - 681 WP_106914394.1 IS6 family transposase IS1216E Transposase
HI837_RS14795 () 183475..183756 - 282 Protein_188 YfbU family protein -
HI837_RS14800 () 184218..185599 + 1382 Protein_189 IS3 family transposase ISLca1 Transposase
HI837_RS14805 () 185833..186705 - 873 WP_138013299.1 ROK family protein -
HI837_RS14810 () 186722..188194 - 1473 WP_016629104.1 glycoside hydrolase family 32 protein -
HI837_RS14815 () 188208..189056 - 849 WP_002313079.1 carbohydrate ABC transporter permease -
HI837_RS14820 () 189053..189919 - 867 WP_002322555.1 sugar ABC transporter permease -
HI837_RS14825 () 189962..190804 - 843 Protein_194 extracellular solute-binding protein -
HI837_RS14830 () 190885..192405 - 1521 WP_002300843.1 IS66 family transposase ISDeal1 Transposase
HI837_RS14835 () 192648..192833 - 186 WP_002305884.1 IS66 family transposase ISEbi1 Transposase
HI837_RS14840 () 192817..192999 - 183 WP_002300846.1 hypothetical protein -
HI837_RS14845 () 193084..193560 - 477 Protein_198 extracellular solute-binding protein -
HI837_RS14850 () 193700..194671 - 972 WP_010729506.1 LacI family DNA-binding transcriptional regulator -
HI837_RS14855 () 194797..195024 - 228 Protein_200 IS110 family transposase -
HI837_RS14860 () 195189..195524 - 336 Protein_201 Tn3 family transposase TnpA_ISXc4 Transposase
HI837_RS14865 () 195706..196311 + 606 WP_002313084.1 Tn3 family transposase TnpR_ISPa40 Transposase
HI837_RS14870 () 196357..196536 - 180 WP_002340501.1 IS21 family transposase ISAar36 Transposase
HI837_RS14875 () 197023..197223 - 201 Protein_204 hypothetical protein -
HI837_RS14880 () 197762..198033 - 272 Protein_205 HAD-IA family hydrolase -
HI837_RS14885 () 198144..199052 + 909 WP_010729754.1 IS982 family transposase ISEfm1 Transposase
HI837_RS14890 () 199111..200913 - 1803 WP_010729753.1 3'-5' exoribonuclease -
HI837_RS14895 () 200976..201818 - 843 WP_002342384.1 hypothetical protein -
HI837_RS14900 () 201834..202055 - 222 WP_002331328.1 helix-turn-helix transcriptional regulator -
HI837_RS14905 () 202198..202476 - 279 Protein_210 site-specific recombinase -
HI837_RS14910 () 202551..203231 + 681 WP_002336713.1 IS6 family transposase IS1216E Transposase
HI837_RS14915 () 203289..204509 - 1221 WP_002339142.1 PAS domain-containing protein -
HI837_RS14920 () 204529..205140 - 612 WP_002339141.1 NAD(P)H-dependent oxidoreductase -
HI837_RS14925 () 205183..206115 - 933 WP_002350224.1 FAD:protein FMN transferase -
HI837_RS14930 () 206452..207747 + 1296 WP_002297218.1 ISL3 family transposase ISEfa11 Transposase
HI837_RS14935 () 208058..208918 - 861 WP_002350223.1 helix-turn-helix domain-containing protein -
HI837_RS14940 () 209065..209716 - 652 Protein_217 IS6 family transposase IS1216V Transposase
HI837_RS14945 () 210192..210509 - 318 WP_076713765.1 type II toxin-antitoxin system RelE/ParE family toxin -
HI837_RS14950 () 210510..210764 - 255 WP_002290397.1 AbrB family transcriptional regulator -
HI837_RS14955 () 211024..211242 - 219 Protein_220 type II toxin-antitoxin system RelE/ParE family toxin -
HI837_RS14960 () 211803..211889 - 87 Protein_221 single-stranded DNA-binding protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance