MGE detailed information

MGE type: Conjugative plasmid        MGE length: 177258 bp
Accession: NZ_CP061397        Location: 1..177258         Organism: Klebsiella pneumoniae strain NU-CRE193       Replicon: plasmid pCRE-193-1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HCV83_RS27185 () 1..1011 + 1011 WP_004152063.1 RepB family plasmid replication initiator protein -
HCV83_RS27190 () 1728..2468 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
HCV83_RS27195 () 3612..4559 + 948 WP_004152065.1 sensor domain-containing diguanylate cyclase -
HCV83_RS27200 () 4586..4897 - 312 WP_071527918.1 EAL domain-containing protein -
HCV83_RS27205 () 4917..5885 + 969 WP_011977741.1 IS5 family transposase IS903B Transposase
HCV83_RS27210 () 6558..6815 - 258 WP_004197688.1 hypothetical protein -
HCV83_RS27215 () 7417..8871 + 1455 WP_020444838.1 putative cyclic di-GMP phosphodiesterase PdeB VF
HCV83_RS27220 () 9854..11131 - 1278 WP_004152070.1 DUF2254 domain-containing protein -
HCV83_RS27225 () 11194..13191 - 1998 WP_004178088.1 choline BCCT transporter BetT -
HCV83_RS27230 () 13343..14040 - 698 Protein_9 IS1 family transposase IS1X2 Transposase
HCV83_RS27240 () 15529..16013 + 485 Protein_11 IS1 family transposase IS1X2 Transposase
HCV83_RS27245 () 16029..16571 + 543 Protein_12 ISL3 family transposase ISKpn25 Transposase
HCV83_RS27250 () 16867..17298 - 432 WP_004178091.1 silver-binding protein SilE -
HCV83_RS27255 () 17549..19024 - 1476 WP_003032875.1 copper/silver sensor histidine kinase SilS -
HCV83_RS27260 () 19017..19697 - 681 WP_001572351.1 Transcriptional regulatory protein CusR VF
HCV83_RS27265 () 19887..20531 + 645 Protein_16 Cation efflux system protein CusC VF
HCV83_RS27270 () 20601..21581 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
HCV83_RS27275 () 21695..21889 + 195 WP_052536218.1 hemolysin expression modulator Hha -
HCV83_RS27280 () 21938..22195 + 258 WP_004152107.1 hypothetical protein -
HCV83_RS27285 () 22271..22525 + 255 WP_004152108.1 hypothetical protein -
HCV83_RS27290 () 22701..22967 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
HCV83_RS27295 () 22955..23437 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
HCV83_RS27300 () 23649..24995 + 1347 WP_020314316.1 ISNCY family transposase ISLad2 Transposase
HCV83_RS27305 () 25496..26750 - 1255 Protein_24 IS3 family transposase ISKpn38 Transposase
HCV83_RS27310 () 26838..27800 - 963 WP_004152113.1 M48 family metalloprotease -
HCV83_RS27315 () 27787..28536 - 750 WP_009483782.1 phosphate-starvation-inducible PsiE family protein -
HCV83_RS27320 () 28774..28971 - 198 WP_004152115.1 hypothetical protein -
HCV83_RS27325 () 28971..31766 - 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
HCV83_RS27330 () 31881..32450 - 570 WP_004152117.1 Spore protein SP21 VF
HCV83_RS27335 () 32485..32766 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
HCV83_RS27340 () 33010..33273 - 264 WP_004118208.1 hypothetical protein -
HCV83_RS27345 () 33288..33551 + 264 WP_004118209.1 IS66 family transposase ISPpu19 Transposase
HCV83_RS27350 () 33496..33612 + 117 Protein_33 transposase domain-containing protein -
HCV83_RS27355 () 33797..34494 + 698 Protein_34 IS1 family transposase IS1X2 Transposase
HCV83_RS27360 () 34753..35733 + 981 WP_000019473.1 IS5 family transposase ISKpn26 Transposase
HCV83_RS27365 () 36315..36834 - 520 Protein_36 IS5 family transposase ISPst7 Transposase
HCV83_RS27370 () 36942..37811 - 870 WP_004152692.1 HTH-type transcriptional activator CmpR VF
HCV83_RS27375 () 37805..38815 - 1011 WP_004152693.1 phosphonate dehydrogenase PtxD -
HCV83_RS27380 () 38824..39651 - 828 WP_004152694.1 phosphonate ABC transporter, permease protein PhnE -
HCV83_RS27385 () 39660..40523 - 864 WP_004152695.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
HCV83_RS27390 () 40520..41347 - 828 WP_004153729.1 Glutamine transport ATP-binding protein GlnQ VF
HCV83_RS27395 () 41689..41997 + 309 Protein_42 IS5 family transposase ISThi1 Transposase
HCV83_RS27400 () 42203..42907 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HCV83_RS27405 () 42970..44163 + 1194 Protein_44 Tn3 family transposase TnpA_ISSba14 Transposase
HCV83_RS27410 () 44211..44879 + 669 WP_044117068.1 IS6 family transposase IS26 Transposase
HCV83_RS27415 () 45069..45884 - 816 WP_000018329.1 Aminoglycoside 3'-phosphotransferase ARG
HCV83_RS27420 () 46035..46739 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
HCV83_RS27425 () 46861..47766 + 906 WP_000219391.1 hypothetical protein ARG
HCV83_RS27430 () 47763..49001 + 1239 WP_000004159.1 MFS transporter -
HCV83_RS27435 () 49001..49585 + 585 WP_001137892.1 TetR family transcriptional regulator -
HCV83_RS27440 () 50078..50842 - 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
HCV83_RS27445 () 50960..51025 - 66 Protein_52 EAL domain-containing protein -
HCV83_RS27450 () 51069..51374 - 306 WP_000130000.1 hypothetical protein Relaxase
HCV83_RS27455 () 51385..52590 - 1206 WP_000184001.1 chromate efflux transporter -
HCV83_RS27460 () 52746..52949 - 204 WP_000376616.1 hypothetical protein -
HCV83_RS27465 () 53077..53916 - 840 WP_000259031.1 Dihydropteroate synthase ARG
HCV83_RS27470 () 53910..54257 - 348 WP_000679427.1 Multidrug transporter EmrE ARG
HCV83_RS27475 () 54421..55212 - 792 WP_001206356.1 Streptomycin 3''-adenylyltransferase ARG
HCV83_RS27480 () 55218..55508 - 291 WP_001336345.1 DUF1010 domain-containing protein -
HCV83_RS27485 () 55620..56117 - 498 WP_001083725.1 Dihydrofolate reductase ARG
HCV83_RS27490 () 56262..57275 + 1014 WP_000845039.1 IS91 family transposase ISAzo26 Transposase
HCV83_RS27495 () 57478..57828 + 351 WP_000454193.1 DUF3330 domain-containing protein -
HCV83_RS27500 () 57954..58514 + 561 WP_000147567.1 Tn3 family transposase TnpR_TnAs3 Transposase
HCV83_RS27505 () 58517..61483 + 2967 WP_001138064.1 Tn3 family transposase TnpA_TnAs3 Transposase
HCV83_RS27510 () 61550..61927 + 378 WP_000656305.1 GNAT family N-acetyltransferase -
HCV83_RS27515 () 62128..62787 - 660 WP_000412211.1 Chloramphenicol acetyltransferase ARG
HCV83_RS27520 () 63066..63763 + 698 Protein_67 IS1 family transposase IS1R Transposase
HCV83_RS27525 () 63778..63927 - 150 Protein_68 IS3 family transposase IS2 Transposase
HCV83_RS27530 () 64404..64676 + 273 WP_000333416.1 His-Xaa-Ser system protein HxsD -
HCV83_RS27535 () 64676..66064 + 1389 WP_004118216.1 His-Xaa-Ser system radical SAM maturase HxsB -
HCV83_RS27540 () 66057..67169 + 1113 WP_000005560.1 His-Xaa-Ser system radical SAM maturase HxsC -
HCV83_RS27545 () 67166..67801 + 636 WP_004118217.1 His-Xaa-Ser repeat protein HxsA -
HCV83_RS27550 () 68349..68735 + 387 WP_020956879.1 IS66 family transposase ISSgsp1 Transposase
HCV83_RS27555 () 68732..69079 + 348 WP_004152557.1 IS66 family transposase ISCfr14 Transposase
HCV83_RS27560 () 69129..70666 + 1538 Protein_75 IS66 family transposase ISCfr14 Transposase
HCV83_RS27565 () 70704..71081 + 378 Protein_76 IS66 family transposase ISEc22 Transposase
HCV83_RS27570 () 72902..74635 - 1734 WP_004118832.1 Glutathione import ATP-binding protein GsiA VF
HCV83_RS27575 () 74643..75590 - 948 WP_004118225.1 acetamidase/formamidase family protein -
HCV83_RS27580 () 75635..77239 - 1605 WP_004152278.1 ABC transporter substrate-binding protein -
HCV83_RS27585 () 77252..78172 - 921 WP_004118227.1 ABC transporter permease -
HCV83_RS27590 () 78172..79020 - 849 WP_004152279.1 ABC transporter permease -
HCV83_RS27595 () 79017..79610 - 594 WP_004118229.1 ANTAR domain-containing protein -
HCV83_RS27600 () 79607..80734 - 1128 WP_004118840.1 transporter substrate-binding protein -
HCV83_RS27605 () 81019..81186 - 168 WP_004118231.1 integrase -
HCV83_RS27610 () 81115..81327 + 213 WP_161989521.1 hypothetical protein -
HCV83_RS27615 () 81328..81813 + 486 Protein_86 IS21 family transposase ISEc62 Transposase
HCV83_RS27620 () 82289..82810 + 522 WP_004118235.1 putative RNA polymerase sigma factor FecI VF
HCV83_RS27625 () 82807..83760 + 954 WP_004118237.1 fec operon regulator FecR -
HCV83_RS27630 () 83846..86170 + 2325 WP_004152280.1 Fe(3+) dicitrate transport protein FecA -
HCV83_RS27635 () 86215..87117 + 903 WP_004118241.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -
HCV83_RS27640 () 87114..88112 + 999 WP_004118243.1 Fe(3+) dicitrate transport system permease protein FecC VF
HCV83_RS27645 () 88109..89065 + 957 WP_004152281.1 Fe(3+) dicitrate transport system permease protein FecD VF
HCV83_RS27650 () 89066..89833 + 768 WP_004152282.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
HCV83_RS27655 () 89932..90225 + 294 WP_004118251.1 IS66 family transposase ISKpn24 Transposase
HCV83_RS27660 () 90300..90527 + 228 Protein_95 IS66 family transposase -
HCV83_RS27665 () 90556..90843 - 288 WP_165765869.1 EAL domain-containing protein -
HCV83_RS27670 () 91177..92187 - 1011 WP_004152284.1 zinc-binding alcohol dehydrogenase family protein -
HCV83_RS27675 () 92648..93730 + 1083 WP_004152286.1 DNA-binding transcriptional repressor LacI -
HCV83_RS27680 () 93852..96926 + 3075 WP_004152287.1 beta-galactosidase -
HCV83_RS27685 () 96978..98231 + 1254 WP_003846917.1 lactose permease -
HCV83_RS27690 () 98323..99292 + 970 Protein_101 IS5 family transposase IS903B Transposase
HCV83_RS27695 () 99937..102246 + 2310 WP_004152290.1 TerB N-terminal domain-containing protein -
HCV83_RS27700 () 102250..103566 + 1317 WP_004152291.1 ATP-binding protein -
HCV83_RS27705 () 103563..105758 + 2196 WP_000093087.1 DEAD/DEAH box helicase -
HCV83_RS27710 () 107205..108062 - 858 WP_004152292.1 incFII family plasmid replication initiator RepA -
HCV83_RS27715 () 108055..108132 - 78 WP_004171457.1 RepA leader peptide Tap -
HCV83_RS27720 () 108349..108627 - 279 WP_004199332.1 replication regulatory protein RepA -
HCV83_RS27725 () 108948..109427 - 480 WP_009485932.1 Phospholipase D VF
HCV83_RS27730 () 109768..110046 - 279 WP_004152296.1 bacteriocin immunity protein -
HCV83_RS27735 () 110048..112369 - 2322 WP_004178051.1 klebicin B-related nuclease bacteriocin -
HCV83_RS27740 () 112726..113271 + 546 WP_004178052.1 hypothetical protein -
HCV83_RS27745 () 113486..113833 - 348 WP_004152301.1 hypothetical protein -
HCV83_RS27750 () 113853..114449 - 597 WP_004178053.1 fertility inhibition protein FinO -
HCV83_RS27755 () 114607..115332 - 726 WP_004152303.1 type-F conjugative transfer system pilin acetylase TraX -
HCV83_RS27760 () 115412..120673 - 5262 WP_004153029.1 Multifunctional conjugation protein TraI Relaxase
HCV83_RS27765 () 120673..122982 - 2310 Protein_116 type IV conjugative transfer system coupling protein TraD -
HCV83_RS27770 () 123342..124073 - 732 WP_004152629.1 complement resistance protein TraT -
HCV83_RS27775 () 124263..124790 - 528 WP_004153030.1 hypothetical protein -
HCV83_RS27780 () 124796..127645 - 2850 WP_004178054.1 conjugal transfer mating pair stabilization protein TraG -
HCV83_RS27785 () 127645..129015 - 1371 WP_004178055.1 conjugal transfer protein TraH -
HCV83_RS27790 () 129002..129430 - 429 WP_004152689.1 hypothetical protein -
HCV83_RS27795 () 129423..129995 - 573 WP_004152688.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
HCV83_RS27800 () 129967..130206 - 240 WP_004152687.1 type-F conjugative transfer system pilin chaperone TraQ -
HCV83_RS27805 () 130217..130969 - 753 WP_004152686.1 type-F conjugative transfer system pilin assembly protein TraF -
HCV83_RS27810 () 130990..131316 - 327 WP_004152685.1 hypothetical protein -
HCV83_RS27815 () 131544..131780 - 237 WP_004152683.1 conjugal transfer protein TrbE -
HCV83_RS27820 () 131812..133767 - 1956 WP_004153093.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
HCV83_RS27825 () 133815..134453 - 639 WP_004152682.1 type-F conjugative transfer system pilin assembly protein TrbC -
HCV83_RS27830 () 134466..135458 - 993 WP_004178057.1 conjugal transfer pilus assembly protein TraU -
HCV83_RS27835 () 135469..136095 - 627 WP_004152590.1 type-F conjugative transfer system protein TraW -
HCV83_RS27840 () 136095..136484 - 390 WP_004152591.1 type-F conjugative transfer system protein TrbI -
HCV83_RS27845 () 136484..139123 - 2640 WP_004152592.1 type IV secretion system protein TraC -
HCV83_RS27850 () 139195..139593 - 399 WP_004153071.1 hypothetical protein -
HCV83_RS27855 () 139889..140293 - 405 WP_004152594.1 hypothetical protein -
HCV83_RS27860 () 140360..140677 - 318 WP_004152595.1 hypothetical protein -
HCV83_RS27865 () 140678..140896 - 219 WP_004171484.1 hypothetical protein -
HCV83_RS27870 () 140920..141210 - 291 WP_004152596.1 hypothetical protein -
HCV83_RS27875 () 141215..141625 - 411 WP_004152597.1 lipase chaperone -
HCV83_RS27880 () 141757..142326 - 570 WP_004152598.1 type IV conjugative transfer system lipoprotein TraV -
HCV83_RS27885 () 142349..142945 - 597 WP_004152599.1 conjugal transfer protein TraP -
HCV83_RS27890 () 142938..144362 - 1425 WP_004152600.1 conjugal transfer protein TraB -
HCV83_RS27895 () 144362..145102 - 741 WP_004152601.1 type-F conjugative transfer system secretin TraK -
HCV83_RS27900 () 145089..145655 - 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
HCV83_RS27905 () 145675..145980 - 306 WP_004178059.1 type IV conjugative transfer system protein TraL -
HCV83_RS27910 () 145994..146362 - 369 WP_004178060.1 type IV conjugative transfer system pilin TraA -
HCV83_RS27915 () 146416..146787 - 372 WP_004208838.1 TraY domain-containing protein -
HCV83_RS27920 () 146871..147557 - 687 WP_011977735.1 transcriptional regulator TraJ family protein -
HCV83_RS27925 () 147780..148172 - 393 WP_004178062.1 relaxosome protein TraM -
HCV83_RS27930 () 148606..149091 + 486 WP_004178063.1 hypothetical protein VF
HCV83_RS27935 () 149124..149453 - 330 WP_011977736.1 hypothetical protein -
HCV83_RS27940 () 149486..150307 - 822 WP_004178064.1 DUF945 domain-containing protein -
HCV83_RS27945 () 151141..151554 - 414 WP_004152722.1 helix-turn-helix domain-containing protein -
HCV83_RS27950 () 151555..151833 - 279 WP_004152721.1 helix-turn-helix domain-containing protein -
HCV83_RS27955 () 151823..152143 - 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
HCV83_RS27960 () 152224..152448 - 225 WP_004152719.1 hypothetical protein -
HCV83_RS27965 () 152459..152671 - 213 WP_004152718.1 hypothetical protein -
HCV83_RS27970 () 152732..153088 - 357 WP_004152717.1 hypothetical protein -
HCV83_RS27975 () 153724..154074 - 351 WP_004152758.1 hypothetical protein -
HCV83_RS27980 () 154071..154343 - 273 WP_004152759.1 hypothetical protein -
HCV83_RS27985 () 155043..155204 - 162 WP_004118124.1 type I toxin-antitoxin system Hok family toxin -
HCV83_RS27990 () 155276..156355 + 1080 WP_004220208.1 IS481 family transposase ISKpn28 Transposase
HCV83_RS27995 () 156533..156907 - 375 WP_004152638.1 hypothetical protein -
HCV83_RS28000 () 156963..157289 - 327 WP_004152639.1 hypothetical protein -
HCV83_RS28005 () 157286..158014 - 729 WP_004152640.1 plasmid SOS inhibition protein A -
HCV83_RS28010 () 158011..158442 - 432 WP_004152641.1 conjugation system SOS inhibitor PsiB -
HCV83_RS28015 () 158509..160545 - 2037 WP_004178066.1 ParB/RepB/Spo0J family partition protein -
HCV83_RS28020 () 160615..160863 - 249 WP_004152643.1 DUF905 domain-containing protein -
HCV83_RS28025 () 160912..161454 - 543 WP_004152644.1 single-stranded DNA-binding protein -
HCV83_RS28030 () 162230..162793 - 564 WP_004152645.1 methyltransferase -
HCV83_RS28035 () 162841..164196 - 1356 WP_004178068.1 DUF3560 domain-containing protein -
HCV83_RS28040 () 164248..164478 - 231 WP_004198570.1 hypothetical protein -
HCV83_RS28045 () 164570..164797 - 228 WP_004178072.1 hypothetical protein -
HCV83_RS28050 () 165579..165896 - 318 WP_004118473.1 hypothetical protein -
HCV83_RS28055 () 165931..166185 - 255 WP_004152754.1 DNA polymerase III subunit theta -
HCV83_RS28060 () 166422..166847 - 426 WP_004118478.1 antirestriction protein -
HCV83_RS28065 () 167368..167598 - 231 WP_004152753.1 hypothetical protein -
HCV83_RS28070 () 167832..169319 - 1488 WP_004178082.1 group II intron reverse transcriptase/maturase -
HCV83_RS28075 () 169722..170147 + 426 WP_004178083.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
HCV83_RS28080 () 170147..171418 + 1272 WP_004152715.1 Y-family DNA polymerase -
HCV83_RS28085 () 171497..171712 + 216 Protein_180 type II toxin-antitoxin system Phd/YefM family antitoxin -
HCV83_RS28090 () 171735..172933 - 1199 Protein_181 IS200-IS605 family transposase IS609 Transposase
HCV83_RS28095 () 174370..175341 - 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
HCV83_RS28100 () 175341..176507 - 1167 WP_000523813.1 Sporulation initiation inhibitor protein Soj VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance