NZ_CP0609334364165..4534448

MGE detailed information

MGE type: Integrative_Conjugative_Elements        MGE length: 170284 bp
Accession: NZ_CP060933        Location: 4364165..4534448         Organism: Escherichia coli strain EC12       Replicon: chromosome


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9199_RS21415 (4359558) 4359558..4359794 - 237 WP_001350028.1 DUF1435 domain-containing protein -
H9199_RS21420 (4359935) 4359935..4360723 + 789 WP_000331602.1 siderophore-iron reductase FhuF -
H9199_RS21425 (4360761) 4360761..4361438 - 678 WP_001300509.1 DNA-binding transcriptional activator BglJ -
H9199_RS21430 (4361396) 4361396..4362121 - 726 WP_000936630.1 response regulator transcription factor -
H9199_RS21435 (4362516) 4362516..4363730 + 1215 Protein_4189 DNA primase -
H9199_RS21440 (4363748) 4363748..4364095 + 348 WP_001055900.1 conjugal transfer protein -
H9199_RS21445 (4364092) 4364092..4364784 + 693 WP_000138552.1 DotI/IcmL family type IV secretion protein -
H9199_RS21450 (4364795) 4364795..4365778 + 984 WP_241408363.1 hypothetical protein VF
H9199_RS21455 (4365781) 4365781..4367070 + 1290 WP_011264042.1 conjugal transfer protein TraO -
H9199_RS21460 (4367070) 4367070..4367774 + 705 WP_001493811.1 IncI1-type conjugal transfer protein TraP -
H9199_RS21465 (4367774) 4367774..4368301 + 528 WP_001055569.1 conjugal transfer protein TraQ -
H9199_RS21470 (4368352) 4368352..4368756 + 405 WP_000086965.1 IncI1-type conjugal transfer protein TraR -
H9199_RS21475 (4368820) 4368820..4369008 + 189 WP_001277255.1 putative conjugal transfer protein TraS -
H9199_RS21480 (4368992) 4368992..4369114 + 123 Protein_4198 conjugal transfer protein TraT -
H9199_RS21485 (4369202) 4369202..4370224 + 1023 WP_000255946.1 IS21 family transposase IS100kyp Transposase
H9199_RS21490 (4370221) 4370221..4371003 + 783 WP_001317493.1 IS21 family transposase IS100kyp Transposase
H9199_RS21495 (4371071) 4371071..4371751 + 681 Protein_4201 IncI1-type conjugal transfer protein TraT -
H9199_RS21500 (4371841) 4371841..4374885 + 3045 WP_012783939.1 IncI1-type conjugal transfer protein TraU -
H9199_RS21505 (4374885) 4374885..4375499 + 615 WP_000337394.1 IncI1-type conjugal transfer protein TraV -
H9199_RS21510 (4375466) 4375466..4376668 + 1203 WP_012783938.1 IncI1-type conjugal transfer protein TraW -
H9199_RS21515 (4376697) 4376697..4377281 + 585 WP_012783937.1 conjugal transfer protein TraX -
H9199_RS21520 (4377378) 4377378..4379546 + 2169 WP_015508354.1 DotA/TraY family protein -
H9199_RS21525 (4379617) 4379617..4380279 + 663 WP_012783935.1 plasmid IncI1-type surface exclusion protein ExcA -
H9199_RS21530 (4380351) 4380351..4380560 - 210 WP_000062603.1 HEAT repeat domain-containing protein -
H9199_RS21535 (4380952) 4380952..4381128 + 177 WP_001054900.1 hypothetical protein -
H9199_RS26035 (4381193) 4381193..4381288 - 96 WP_000609148.1 DinQ-like type I toxin DqlB -
H9199_RS21545 (4381733) 4381733..4382701 + 969 WP_000654811.1 IS5 family transposase IS903B Transposase
H9199_RS21550 (4382854) 4382854..4383105 + 252 WP_001291964.1 hypothetical protein -
H9199_RS21555 (4383177) 4383177..4383329 - 153 WP_001387489.1 Hok/Gef family protein -
H9199_RS21560 (4383956) 4383956..4384735 + 780 WP_275450201.1 protein FinQ -
H9199_RS21565 (4385042) 4385042..4386250 + 1209 WP_001703845.1 IncI1-type conjugal transfer protein TrbA -
H9199_RS21570 (4386269) 4386269..4387339 + 1071 WP_012783932.1 IncI1-type conjugal transfer protein TrbB -
H9199_RS21575 (4387332) 4387332..4389623 + 2292 WP_012783931.1 F-type conjugative transfer protein TrbC -
H9199_RS21580 (4389660) 4389660..4392359 - 2700 WP_012783930.1 IncI1-type relaxase NikB -
H9199_RS21585 (4392370) 4392370..4392702 - 333 WP_001283947.1 IncI1-type relaxosome accessory protein NikA -
H9199_RS21590 (4392936) 4392936..4393271 + 336 WP_000157082.1 molybdopterin-guanine dinucleotide biosynthesis protein MobC -
H9199_RS21595 (4393357) 4393357..4394205 - 849 WP_012783929.1 DUF4942 domain-containing protein -
H9199_RS21600 (4394785) 4394785..4395036 + 252 WP_000148285.1 helix-turn-helix transcriptional regulator -
H9199_RS21605 (4395067) 4395067..4395273 - 207 WP_000150314.1 hypothetical protein VF
H9199_RS21610 (4395335) 4395335..4396237 - 903 WP_023150544.1 Recombination-promoting nuclease RpnA VF
H9199_RS21615 (4396234) 4396234..4396623 - 390 WP_000833767.1 hypothetical protein -
H9199_RS21620 (4396800) 4396800..4397066 - 267 WP_000804663.1 hypothetical protein -
H9199_RS21625 (4397160) 4397160..4397594 - 435 WP_000218858.1 hypothetical protein -
H9199_RS21630 (4398323) 4398323..4398823 - 501 WP_000117626.1 antirestriction protein ArdA -
H9199_RS21635 (4399285) 4399285..4399881 - 597 WP_000977995.1 hypothetical protein -
H9199_RS21640 (4399878) 4399878..4400597 - 720 WP_012783927.1 plasmid SOS inhibition protein A -
H9199_RS21645 (4400594) 4400594..4401028 - 435 WP_001402001.1 conjugation system SOS inhibitor PsiB -
H9199_RS21650 (4401081) 4401081..4403039 - 1959 WP_063267868.1 ParB/RepB/Spo0J family partition protein -
H9199_RS21655 (4403098) 4403098..4403331 - 234 WP_015508350.1 DUF905 domain-containing protein -
H9199_RS21660 (4403334) 4403334..4403915 - 582 WP_277626151.1 single-stranded DNA-binding protein -
H9199_RS21665 (4404299) 4404299..4404562 - 264 WP_158213465.1 hypothetical protein -
H9199_RS21670 (4404700) 4404700..4404891 - 192 WP_001027516.1 hypothetical protein -
H9199_RS21675 (4404888) 4404888..4405310 - 423 WP_000271703.1 DUF1380 family protein -
H9199_RS21680 (4405357) 4405357..4405782 - 426 WP_001198889.1 antirestriction protein -
H9199_RS21685 (4406195) 4406195..4406965 - 771 WP_012783922.1 hypothetical protein -
H9199_RS21690 (4407010) 4407010..4407528 - 519 WP_223350510.1 DUF1380 family protein -
H9199_RS21695 (4407458) 4407458..4407679 - 222 WP_001104873.1 hypothetical protein -
H9199_RS21700 (4407680) 4407680..4408363 - 684 WP_000086127.1 DNA methylase -
H9199_RS21705 (4408439) 4408439..4408750 - 312 WP_033863049.1 hypothetical protein -
H9199_RS21710 (4408754) 4408754..4409176 - 423 WP_000774832.1 plasmid partitioning/stability family protein -
H9199_RS21715 (4409179) 4409179..4410159 - 981 WP_012783921.1 plasmid segregation protein ParM -
H9199_RS21720 (4410497) 4410497..4410832 + 336 WP_001340323.1 hypothetical protein -
H9199_RS21725 (4410837) 4410837..4410923 - 87 Protein_4247 hypothetical protein -
H9199_RS21730 (4410927) 4410927..4411829 - 903 WP_001739825.1 DUF1281 domain-containing protein -
H9199_RS21735 (4412247) 4412247..4412495 + 249 WP_000618110.1 DinI-like family protein -
H9199_RS21740 (4412492) 4412492..4412929 + 438 WP_000109071.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
H9199_RS21745 (4412929) 4412929..4414200 + 1272 WP_001703910.1 Y-family DNA polymerase -
H9199_RS21750 (4414396) 4414396..4415022 + 627 WP_000587689.1 ParA family plasmid-partitioning AAA ATPase -
H9199_RS21755 (4415019) 4415019..4415321 + 303 WP_001245884.1 hypothetical protein -
H9199_RS21760 (4415860) 4415860..4417254 - 1395 WP_241408364.1 protein YagA -
H9199_RS21765 (4417197) 4417197..4417541 + 345 Protein_4255 WbuC family cupin fold metalloprotein -
H9199_RS21770 (4417588) 4417588..4418463 - 876 WP_015387340.1 Beta-lactamase CTX-M-1 ARG
H9199_RS21775 (4418719) 4418719..4419981 - 1263 WP_000608644.1 IS1380 family transposase ISEcp1 Transposase
H9199_RS21780 (4420402) 4420402..4421172 + 771 WP_029402187.1 threonine/serine exporter ThrE family protein -
H9199_RS21785 (4421163) 4421163..4421636 + 474 WP_000538188.1 threonine/serine exporter -
H9199_RS21790 (4421743) 4421743..4422282 + 540 WP_000098816.1 primosomal protein DnaT -
H9199_RS21795 (4422285) 4422285..4423022 + 738 WP_000799911.1 IS21 family transposase ISSme2 Transposase
H9199_RS21800 (4423071) 4423071..4423565 + 495 WP_001308243.1 DUF2501 domain-containing protein YjjA -
H9199_RS21805 (4423819) 4423819..4426110 + 2292 WP_001292653.1 phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase -
H9199_RS21810 (4426249) 4426249..4427271 - 1023 WP_000106030.1 L-galactonate oxidoreductase -
H9199_RS21815 (4427410) 4427410..4428324 + 915 WP_000091569.1 GntR family transcriptional regulator -
H9199_RS21820 (4428539) 4428539..4429900 + 1362 WP_000410129.1 MFS transporter -
H9199_RS21825 (4429949) 4429949..4431613 - 1665 WP_000919567.1 Methyl-accepting chemotaxis protein I VF
H9199_RS21830 (4431732) 4431732..4432178 - 447 WP_000543915.1 homoprotocatechuate degradation operon regulator HpaR -
H9199_RS21835 (4432450) 4432450..4433739 + 1290 WP_000679092.1 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase -
H9199_RS21840 (4433736) 4433736..4435202 + 1467 WP_000757512.1 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase -
H9199_RS21845 (4435204) 4435204..4436055 + 852 WP_000516990.1 3,4-dihydroxyphenylacetate 2,3-dioxygenase -
H9199_RS21850 (4436065) 4436065..4436445 + 381 WP_001119864.1 5-carboxymethyl-2-hydroxymuconate Delta-isomerase -
H9199_RS21855 (4436556) 4436556..4437359 + 804 WP_000459750.1 2-oxo-hepta-3-ene-1,7-dioic acid hydratase -
H9199_RS21860 (4437370) 4437370..4438158 + 789 WP_000431705.1 4-hydroxy-2-oxoheptanedioate aldolase -
H9199_RS21865 (4438333) 4438333..4439709 + 1377 WP_001285769.1 4-hydroxyphenylacetate permease -
H9199_RS21870 (4439719) 4439719..4440609 + 891 WP_000332891.1 4-hydroxyphenylacetate catabolism regulatory protein HpaA -
H9199_RS21875 (4440860) 4440860..4442422 + 1563 WP_029402184.1 4-hydroxyphenylacetate 3-monooxygenase oxygenase component VF
H9199_RS21880 (4442440) 4442440..4442952 + 513 WP_001175455.1 4-hydroxyphenylacetate 3-monooxygenase reductase subunit -
H9199_RS21885 (4443342) 4443342..4445492 + 2151 WP_001298933.1 pyruvate/proton symporter BtsT -
H9199_RS21890 (4445623) 4445623..4445826 + 204 WP_000467859.1 YbdD/YjiX family protein -
H9199_RS21895 (4445837) 4445837..4446793 + 957 WP_001295525.1 GTPase -
H9199_RS21900 (4446827) 4446827..4447129 - 303 WP_019842999.1 BrnA antitoxin family protein Antitoxin Detail
H9199_RS21905 (4447116) 4447116..4447403 - 288 WP_001131965.1 BrnT family toxin Toxin Detail
H9199_RS21910 (4447600) 4447600..4448766 + 1167 WP_000800825.1 restriction endonuclease -
H9199_RS21915 (4448830) 4448830..4450449 + 1620 WP_001029743.1 class I SAM-dependent DNA methyltransferase -
H9199_RS21920 (4450439) 4450439..4451740 + 1302 WP_100729279.1 restriction endonuclease subunit S -
H9199_RS21930 (4452735) 4452735..4455998 + 3264 WP_000058885.1 HsdR family type I site-specific deoxyribonuclease -
H9199_RS21935 (4456213) 4456213..4456551 + 339 WP_000132624.1 endoribonuclease SymE -
H9199_RS21940 (4456639) 4456639..4456791 - 153 WP_229018381.1 cytoplasmic protein -
H9199_RS21945 (4456934) 4456934..4458346 + 1413 WP_000199313.1 PLP-dependent aminotransferase family protein -
H9199_RS21950 (4458589) 4458589..4459533 - 945 WP_000181173.1 Recombination-promoting nuclease RpnD VF
H9199_RS21955 (4460001) 4460001..4461233 + 1233 WP_100729270.1 multidrug efflux MFS transporter MdtM -
H9199_RS21960 (4461274) 4461274..4462554 + 1281 WP_001037392.1 DUF445 domain-containing protein -
H9199_RS21965 (4462670) 4462670..4463821 + 1152 WP_001307557.1 double-cubane-cluster-containing anaerobic reductase -
H9199_RS21970 (4463831) 4463831..4464598 + 768 WP_000222495.1 putative 2-hydroxyacyl-CoA dehydratase activator YjiL -
H9199_RS21975 (4464595) 4464595..4464852 + 258 WP_000657676.1 DUF3343 domain-containing protein -
H9199_RS21980 (4464917) 4464917..4465777 + 861 WP_001298932.1 YjiK family protein -
H9199_RS21985 (4465845) 4465845..4467023 + 1179 WP_001141192.1 MFS transporter -
H9199_RS21990 (4467036) 4467036..4467590 - 555 WP_001151854.1 RNA 2'-phosphotransferase -
H9199_RS21995 (4467840) 4467840..4468523 + 684 WP_072649507.1 nucleoside recognition domain-containing protein -
H9199_RS22000 (4468520) 4468520..4468981 + 462 WP_000211971.1 YjiG family protein -
H9199_RS22005 (4468994) 4468994..4470166 + 1173 WP_000568406.1 beta-aspartyl-peptidase -
H9199_RS22010 (4470231) 4470231..4471142 + 912 WP_000340764.1 hypochlorite stress DNA-binding transcriptional regulator HypT -
H9199_RS22015 (4471135) 4471135..4471527 - 393 WP_000986215.1 anti-adapter protein IraD -
H9199_RS22020 (4471524) 4471524..4471607 - 84 WP_120795393.1 iraD leader peptide IdlP -
H9199_RS26040 (4471723) 4471723..4471866 - 144 WP_001329085.1 protein YtiD -
H9199_RS22025 (4472200) 4472200..4473030 + 831 WP_000062558.1 DUF2686 family protein -
H9199_RS22030 (4473171) 4473171..4473944 - 774 WP_000833679.1 Uxu operon transcriptional regulator -
H9199_RS22035 (4474159) 4474159..4475619 - 1461 WP_029402182.1 fructuronate reductase -
H9199_RS22040 (4475700) 4475700..4476884 - 1185 WP_000438591.1 mannonate dehydratase -
H9199_RS22045 (4477224) 4477224..4478567 + 1344 WP_000558251.1 gluconate permease GntP -
H9199_RS22050 (4478810) 4478810..4479712 - 903 WP_000832227.1 Type 1 fimbrin D-mannose specific adhesin VF
H9199_RS22055 (4479732) 4479732..4480235 - 504 WP_000870592.1 Protein FimG VF
H9199_RS22060 (4480248) 4480248..4480778 - 531 WP_042630973.1 Protein FimF VF
H9199_RS22065 (4480788) 4480788..4483424 - 2637 WP_000120942.1 Outer membrane usher protein FimD VF
H9199_RS22070 (4483491) 4483491..4484216 - 726 WP_241408365.1 Chaperone protein FimC VF
H9199_RS22075 (4484253) 4484253..4484792 - 540 WP_000824109.1 putative major fimbrial subunit LpfA VF
H9199_RS22080 (4484857) 4484857..4485405 - 549 WP_000695561.1 Type-1 fimbrial protein, A chain VF
H9199_RS22085 (4485886) 4485886..4486482 - 597 WP_000044711.1 Tyrosine recombinase XerD VF
H9199_RS22090 (4486960) 4486960..4487562 - 603 WP_000790583.1 Tyrosine recombinase XerC VF
H9199_RS22095 (4489016) 4489016..4489474 + 459 Protein_4322 N-acetylneuraminic acid outer membrane channel NanC -
H9199_RS22105 (4490808) 4490808..4491068 + 261 Protein_4324 N-acetylneuraminic acid outer membrane channel NanC -
H9199_RS22110 (4491088) 4491088..4492194 + 1107 WP_001295733.1 N-acetylneuraminate epimerase -
H9199_RS22115 (4492258) 4492258..4493238 + 981 WP_000991462.1 sialate O-acetylesterase -
H9199_RS22120 (4493348) 4493348..4493553 + 206 Protein_4327 HNH endonuclease -
H9199_RS22125 (4493821) 4493821..4495047 - 1227 Protein_4328 helicase YjhR -
H9199_RS22130 (4495125) 4495125..4495424 + 300 WP_001332034.1 GNAT family N-acetyltransferase -
H9199_RS22135 (4495801) 4495801..4496058 + 258 WP_001054379.1 YjhX family toxin -
H9199_RS22140 (4496070) 4496070..4496617 + 548 Protein_4331 N-acetyltransferase -
H9199_RS22145 (4496673) 4496673..4497419 + 747 WP_000354249.1 class I SAM-dependent methyltransferase -
H9199_RS22150 (4497589) 4497589..4497807 + 219 WP_001348444.1 hypothetical protein -
H9199_RS22155 (4497845) 4497845..4497961 + 117 Protein_4334 VOC family protein -
H9199_RS22160 (4498206) 4498206..4499327 + 1122 WP_000010833.1 M42 family metallopeptidase -
H9199_RS22165 (4499324) 4499324..4499602 + 279 WP_000722973.1 PTS sugar transporter subunit IIB SgcB -
H9199_RS22170 (4499614) 4499614..4500927 + 1314 WP_029402181.1 PTS sugar transporter subunit IIC SgcC -
H9199_RS22175 (4500940) 4500940..4501746 + 807 WP_000118626.1 BtpA family protein SgcQ -
H9199_RS22180 (4501877) 4501877..4502308 + 432 WP_000606405.1 SgcA family PTS sugar transporter subunit IIA -
H9199_RS22185 (4502320) 4502320..4502952 + 633 WP_000600624.1 ribulose-phosphate 3 epimerase family protein -
H9199_RS22190 (4502969) 4502969..4503751 + 783 WP_000082779.1 DeoR/GlpR family DNA-binding transcription regulator -
H9199_RS22195 (4504054) 4504054..4504842 + 789 WP_000251800.1 IclR family transcriptional regulator -
H9199_RS22200 (4504847) 4504847..4505752 + 906 WP_000714563.1 dihydrodipicolinate synthase family protein -
H9199_RS22205 (4505763) 4505763..4507730 + 1968 WP_000116325.1 xylonate dehydratase YjhG -
H9199_RS22210 (4507837) 4507837..4509186 + 1350 WP_001128363.1 GntP family permease -
H9199_RS22215 (4509533) 4509533..4510519 + 987 WP_000373366.1 sugar-binding transcriptional regulator -
H9199_RS22220 (4510560) 4510560..4511564 - 1005 WP_000471144.1 GRP family sugar transporter -
H9199_RS22225 (4511668) 4511668..4512309 - 642 WP_000439686.1 L-fuculose-phosphate aldolase -
H9199_RS22230 (4512340) 4512340..4513455 - 1116 WP_001022015.1 S-methyl-5-thioribose-1-phosphate isomerase -
H9199_RS22235 (4513465) 4513465..4514724 - 1260 WP_000132325.1 S-methyl-5-thioribose kinase -
H9199_RS22240 (4515524) 4515524..4516461 + 938 Protein_4351 glycosyltransferase -
H9199_RS22245 (4516882) 4516882..4518957 + 2076 WP_000366620.1 AAA family ATPase -
H9199_RS22250 (4518950) 4518950..4520236 + 1287 WP_000504875.1 McrC family protein -
H9199_RS22255 (4520517) 4520517..4522083 + 1567 Protein_4354 Alw26I/Eco31I/Esp3I family type II restriction endonuclease -
H9199_RS22260 (4522096) 4522096..4523286 - 1191 WP_001295727.1 DNA (cytosine-5-)-methyltransferase -
H9199_RS22265 (4523279) 4523279..4524901 - 1623 WP_001295726.1 Alw26I/Eco31I/Esp3I family type II restriction adenine-specific DNA-methyltransferase -
H9199_RS22270 (4525371) 4525371..4526912 - 1542 WP_001298859.1 IS21 family transposase ISEc12 Transposase
H9199_RS22275 (4527506) 4527506..4527682 - 177 Protein_4358 IS3 family transposase ISSen1 Transposase
H9199_RS22280 (4528049) 4528049..4528198 - 150 Protein_4359 hypothetical protein -
H9199_RS22285 (4528304) 4528304..4528480 - 177 WP_000839286.1 DUF957 domain-containing protein -
H9199_RS22290 (4528497) 4528497..4528985 - 489 WP_000761690.1 DUF5983 family protein -
H9199_RS22295 (4528982) 4528982..4529359 - 378 WP_000854759.1 TA system toxin CbtA family protein Toxin Detail
H9199_RS22300 (4529449) 4529449..4529817 - 369 WP_001295723.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin Detail
H9199_RS22305 (4529980) 4529980..4530201 - 222 WP_000692345.1 DUF987 domain-containing protein -
H9199_RS22310 (4530264) 4530264..4530740 - 477 WP_001186775.1 RadC family protein -
H9199_RS22315 (4530756) 4530756..4531229 - 474 WP_000855059.1 antirestriction protein -
H9199_RS22320 (4531569) 4531569..4532387 - 819 WP_042631095.1 DUF932 domain-containing protein -
H9199_RS22325 (4532505) 4532505..4532700 - 196 Protein_4368 DUF905 family protein -
H9199_RS22330 (4532771) 4532771..4532962 - 192 Protein_4369 autotransporter domain-containing protein -
H9199_RS22335 (4533046) 4533046..4534068 + 1023 WP_000255946.1 IS21 family transposase IS100kyp Transposase
H9199_RS22340 (4534065) 4534065..4534847 + 783 WP_001317493.1 IS21-like element IS100kyp family helper ATPase IstB -
H9199_RS22345 (4534913) 4534913..4535767 - 855 Protein_4372 autotransporter domain-containing protein -
H9199_RS22350 (4536803) 4536803..4537405 - 603 WP_000813435.1 hypothetical protein -
H9199_RS22355 (4537501) 4537501..4537707 - 207 WP_000211308.1 helix-turn-helix domain-containing protein -
H9199_RS22360 (4538481) 4538481..4538630 + 150 WP_071526287.1 Hha/YmoA family nucleoid-associated regulatory protein -
H9199_RS22365 (4538963) 4538963..4539160 - 198 WP_001547002.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance