MGE detailed information

MGE type: Conjugative plasmid        MGE length: 168221 bp
Accession: NZ_CP060893        Location: 1..168221         Organism: Escherichia coli strain EC22       Replicon: plasmid pEC22-NDM-5


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9207_RS23495 (H9207_23270) 1..1011 + 1011 WP_000200069.1 RepB family plasmid replication initiator protein -
H9207_RS23500 (H9207_23275) 1860..2183 + 324 Protein_1 IS110 family transposase ISSm1 Transposase
H9207_RS23505 (H9207_23280) 2218..3018 - 801 Protein_2 Tn3 family transposase TnpA_Tn5403 Transposase
H9207_RS23510 (H9207_23285) 3087..3344 + 258 Protein_3 IS3 family transposase ISEc52 Transposase
H9207_RS23515 (H9207_23290) 3357..4448 - 1092 Protein_4 IS30 family transposase IS30D Transposase
H9207_RS23520 (H9207_23295) 4505..5718 + 1214 WP_162829202.1 IS3 family transposase IS1203 Transposase
H9207_RS23525 (H9207_23300) 5760..5858 - 99 Protein_6 type I restriction endonuclease -
H9207_RS23530 (H9207_23305) 6062..7927 - 1866 WP_072851607.1 DUF262 domain-containing protein -
H9207_RS23535 (H9207_23310) 8257..8954 + 698 WP_103215986.1 IS1 family transposase IS1G Transposase
H9207_RS23540 (H9207_23315) 9148..9573 - 426 WP_224672778.1 WYL domain-containing protein -
H9207_RS23545 (H9207_23320) 9579..10247 - 669 Protein_10 IS5-like element ISKpn26 family transposase -
H9207_RS23550 (H9207_23325) 10335..10577 - 243 Protein_11 N-acetylneuraminic acid mutarotase -
H9207_RS23555 (H9207_23330) 10802..11905 - 1104 WP_000777276.1 type II Zorya anti-phage system protein ZorE -
H9207_RS23560 (H9207_23335) 11909..12616 - 708 WP_000357807.1 type II Zorya anti-phage system protein ZorB2 -
H9207_RS23565 (H9207_23340) 12623..14275 - 1653 WP_000880884.1 type II Zorya anti-phage system protein ZorA2 -
H9207_RS23570 (H9207_23345) 14487..17825 + 3339 WP_241407648.1 STY4851/ECs_5259 family protein -
H9207_RS23575 (H9207_23350) 17825..24139 + 6315 WP_094885491.1 DEAD/DEAH box helicase -
H9207_RS23580 (H9207_23355) 24363..27221 + 2859 WP_001041504.1 helicase-related protein -
H9207_RS23585 (H9207_23360) 27224..32134 + 4911 WP_094885493.1 class I SAM-dependent DNA methyltransferase -
H9207_RS23590 (H9207_23365) 32134..38475 + 6342 WP_094885495.1 DEAD/DEAH box helicase -
H9207_RS23595 (H9207_23370) 38472..40586 + 2115 WP_094885497.1 ATP-dependent helicase -
H9207_RS23600 (H9207_23375) 40747..41689 + 943 Protein_21 IS3 family transposase IS2 Transposase
H9207_RS23605 (H9207_23380) 41716..42412 - 697 Protein_22 IS1 family transposase -
H9207_RS23610 (H9207_23385) 42806..43834 + 1029 WP_072851570.1 tyrosine-type recombinase/integrase -
H9207_RS23615 (H9207_23390) 44072..44452 - 381 WP_024166788.1 type II toxin-antitoxin system death-on-curing family toxin Toxin Detail
H9207_RS23620 (H9207_23395) 44452..44673 - 222 WP_033545779.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin Detail
H9207_RS23625 (H9207_23400) 44746..45138 - 393 WP_000506718.1 S24 family peptidase -
H9207_RS23630 (H9207_23405) 45250..45498 - 249 WP_001286530.1 DNA polymerase III subunit theta -
H9207_RS23635 (H9207_23410) 45501..45767 - 267 WP_000946114.1 hypothetical protein -
H9207_RS23640 (H9207_23415) 45837..46127 - 291 WP_048659782.1 hypothetical protein -
H9207_RS23645 (H9207_23425) 46255..46959 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
H9207_RS23650 (H9207_23430) 47012..49225 + 2214 Protein_31 Tn3 family transposase ISEc63 Transposase
H9207_RS23655 (H9207_23435) 49825..50211 + 387 WP_001039463.1 plasmid stabilization protein StbA -
H9207_RS23660 (H9207_23440) 50220..50411 + 192 WP_000861580.1 hypothetical protein -
H9207_RS23665 (H9207_23445) 50489..53428 + 2940 WP_072851586.1 AAA family ATPase -
H9207_RS23670 (H9207_23450) 53425..54849 + 1425 WP_072851583.1 tetratricopeptide repeat protein -
H9207_RS23675 (H9207_23455) 55036..56004 + 969 WP_000654804.1 IS5 family transposase IS903B Transposase
H9207_RS23680 56108..56533 + 426 WP_224672791.1 hypothetical protein -
H9207_RS23685 (H9207_23465) 56549..57337 + 789 WP_224672790.1 phage tail protein -
H9207_RS23690 (H9207_23470) 57249..59000 - 1752 Protein_39 Tn3 family transposase TnpA_TnAs1 Transposase
H9207_RS23695 (H9207_23475) 59004..59396 + 393 WP_001351729.1 isochorismatase family cysteine hydrolase -
H9207_RS23700 (H9207_23480) 59534..60418 + 885 WP_000058717.1 EamA family transporter -
H9207_RS23705 (H9207_23485) 60450..61647 - 1198 Protein_42 hypothetical protein ARG
H9207_RS23710 (H9207_23490) 61753..61856 + 104 Protein_43 TetR family transcriptional regulator -
H9207_RS23715 (H9207_23495) 61863..63077 - 1215 Protein_44 Tn3-like element TnAs1 family transposase -
H9207_RS23720 (H9207_23500) 63081..63641 - 561 WP_001161490.1 recombinase family protein -
H9207_RS23725 (H9207_23505) 64016..64876 - 861 WP_015058868.1 Beta-lactamase TEM ARG
H9207_RS23730 (H9207_23510) 65059..65616 - 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
H9207_RS23735 (H9207_23515) 65778..68783 + 3006 WP_001143775.1 Tn3 family transposase TnpA_Tn3 Transposase
H9207_RS23740 (H9207_23520) 68785..69168 + 384 WP_094885533.1 hypothetical protein -
H9207_RS23745 (H9207_23525) 69363..70067 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
H9207_RS23750 (H9207_23530) 70314..70787 - 474 WP_004201280.1 Dihydrofolate reductase type 1 ARG
H9207_RS23755 (H9207_23535) 70943..72055 + 1113 WP_024166810.1 IS91 family transposase ISAzo26 Transposase
H9207_RS23760 (H9207_23540) 72001..72705 - 705 WP_001067855.1 IS6-like element IS26 family transposase -
H9207_RS23765 (H9207_23545) 72772..73388 - 617 Protein_54 transposase -
H9207_RS23770 (H9207_23550) 73783..74439 + 657 WP_001516695.1 Pentapeptide repeat protein ARG
H9207_RS23775 (H9207_23555) 74758..75186 - 429 Protein_56 Tn3 family transposase TnpR_ISMex22 Transposase
H9207_RS23780 (H9207_23560) 75219..76610 - 1392 WP_001493761.1 ISKra4 family transposase ISKpn19 Transposase
H9207_RS23785 (H9207_23565) 76647..77219 - 573 WP_001493762.1 Tn3 family transposase TnpR_ISPa40 Transposase
H9207_RS23790 (H9207_23570) 77356..77901 - 546 WP_001493763.1 plasmid pRiA4b ORF-3 family protein -
H9207_RS23795 (H9207_23575) 78064..78306 + 243 WP_000844627.1 transposase -
H9207_RS23800 (H9207_23580) 78338..78988 - 651 WP_001493764.1 tetracycline resistance transcriptional repressor TetR(A) -
H9207_RS23805 (H9207_23585) 79094..80293 + 1200 WP_000804063.1 tetracycline efflux MFS transporter Tet(A) -
H9207_RS23810 (H9207_23590) 80260..80448 - 189 Protein_63 IS91 family transposase -
H9207_RS23815 (H9207_23595) 80560..80865 - 306 WP_001255015.1 HTH-type transcriptional regulator CynR VF
H9207_RS23820 (H9207_23600) 80893..82107 - 1215 WP_000214121.1 Bicyclomycin resistance protein ARG
H9207_RS23825 (H9207_23605) 82324..83208 - 885 WP_001447541.1 DUF3363 domain-containing protein -
H9207_RS23830 (H9207_23610) 83239..84732 - 1494 WP_001120888.1 IS91 family transposase ISVsa3 Transposase
H9207_RS23835 (H9207_23615) 84943..85167 - 225 WP_000743213.1 hypothetical protein -
H9207_RS23840 (H9207_23620) 85164..85901 - 738 WP_001446887.1 Tn3 family transposase TnpR_TnEc1 Transposase
H9207_RS23845 (H9207_23625) 86387..86527 - 141 WP_001044210.1 hypothetical protein -
H9207_RS23850 (H9207_23630) 86533..87237 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
H9207_RS23855 (H9207_23635) 87296..87430 + 135 WP_023408307.1 divalent cation tolerance protein CutA -
H9207_RS23860 87435..87809 + 375 Protein_73 protein-disulfide reductase DsbD family protein -
H9207_RS23865 87909..88466 + 558 Protein_74 twin-arginine translocation (TAT) pathway signal sequence domain protein -
H9207_RS23870 (H9207_23645) 88477..89115 - 639 WP_004201168.1 phosphoribosylanthranilate isomerase -
H9207_RS23875 (H9207_23650) 89120..89485 - 366 WP_004201167.1 bleomycin binding protein Ble-MBL -
H9207_RS23880 (H9207_23655) 89489..90301 - 813 WP_023408309.1 Metallo-beta-lactamase type 2 ARG
H9207_RS23885 (H9207_23660) 90536..91516 + 981 WP_000019402.1 IS5 family transposase IS5D Transposase
H9207_RS23890 (H9207_23665) 91625..92569 - 945 WP_100183899.1 IS30 family transposase ISAba125 Transposase
H9207_RS23895 (H9207_23670) 92846..95863 - 3018 WP_004199413.1 Tn3 family transposase TnpA_IS3000 Transposase
H9207_RS23900 (H9207_23675) 96007..96552 + 546 Protein_81 Tn3 family transposase TnpA_Tn3 Transposase
H9207_RS25355 96771..96866 - 96 WP_000609145.1 DinQ-like type I toxin DqlB -
H9207_RS23905 (H9207_23685) 97671..97949 - 279 WP_001093608.1 hypothetical protein -
H9207_RS23910 (H9207_23690) 97946..98221 - 276 WP_000557557.1 hypothetical protein -
H9207_RS23915 (H9207_23695) 98239..98493 - 255 WP_000510385.1 hypothetical protein -
H9207_RS23920 (H9207_23700) 98603..99424 - 822 WP_000196235.1 SprT-like domain-containing protein -
H9207_RS23925 (H9207_23705) 99421..99600 - 180 WP_023408316.1 hypothetical protein -
H9207_RS23930 (H9207_23710) 99617..99883 - 267 WP_032072053.1 hypothetical protein -
H9207_RS23935 (H9207_23715) 99873..100523 + 651 WP_000351937.1 YkgJ family cysteine cluster protein -
H9207_RS23940 (H9207_23720) 100561..101016 - 456 WP_001293458.1 H-NS family nucleoid-associated regulatory protein -
H9207_RS23945 (H9207_23725) 101028..103355 - 2328 WP_004199098.1 type IA DNA topoisomerase -
H9207_RS23950 (H9207_23730) 103359..104621 - 1263 WP_000517490.1 ATP-binding protein -
H9207_RS23955 (H9207_23735) 104704..105198 - 495 WP_001215543.1 thermonuclease family protein -
H9207_RS23960 (H9207_23740) 105195..105521 - 327 WP_004208538.1 hypothetical protein -
H9207_RS23965 (H9207_23745) 105607..105921 - 315 WP_000754496.1 TrbM/KikA/MpfK family conjugal transfer protein -
H9207_RS23970 (H9207_23750) 106009..106401 - 393 WP_000738524.1 cag pathogenicity island Cag12 family protein -
H9207_RS23975 (H9207_23755) 106398..108233 - 1836 WP_000053822.1 type IV secretory system conjugative DNA transfer family protein -
H9207_RS23980 (H9207_23760) 108236..109270 - 1035 WP_000650512.1 Type IV secretion system protein PtlH VF
H9207_RS23985 (H9207_23765) 109267..109464 - 198 WP_000629109.1 DNA-binding protein -
H9207_RS23990 (H9207_23770) 109466..110680 - 1215 WP_001295060.1 Type IV secretion system protein virB10 VF
H9207_RS23995 (H9207_23775) 110677..111606 - 930 WP_000783386.1 TrbG/VirB9 family P-type conjugative transfer protein -
H9207_RS24000 (H9207_23780) 111612..112340 - 729 WP_004199085.1 Type IV secretion system protein virB8 VF
H9207_RS24005 (H9207_23785) 112535..113590 - 1056 WP_000235886.1 hypothetical protein VF
H9207_RS24010 (H9207_23790) 113602..113859 - 258 WP_000759841.1 EexN family lipoprotein -
H9207_RS24015 (H9207_23795) 113869..114639 - 771 WP_000716326.1 type IV secretion system protein -
H9207_RS24020 (H9207_23800) 114649..117402 - 2754 WP_015060057.1 Type IV secretion system protein virB4 VF
H9207_RS24025 (H9207_23805) 117427..117717 - 291 WP_000916156.1 TrbC/VirB2 family protein -
H9207_RS24030 (H9207_23810) 117701..118345 - 645 WP_000953538.1 Type IV secretion system protein virB1 VF
H9207_RS24035 (H9207_23815) 118578..119087 - 510 WP_000455437.1 transcription termination/antitermination NusG family protein -
H9207_RS24040 (H9207_23820) 119440..120600 - 1161 WP_004199101.1 hypothetical protein Relaxase
H9207_RS24045 (H9207_23825) 120603..121148 - 546 WP_001348698.1 DNA distortion polypeptide 1 -
H9207_RS24050 (H9207_23835) 121489..121746 - 258 WP_004199355.1 hypothetical protein -
H9207_RS24055 (H9207_23840) 121743..121907 - 165 WP_000004083.1 hypothetical protein -
H9207_RS24060 (H9207_23845) 121982..122320 - 339 WP_001099725.1 hypothetical protein -
H9207_RS24065 (H9207_23850) 122414..122656 - 243 WP_000008707.1 hypothetical protein -
H9207_RS24070 (H9207_23855) 122646..122915 - 270 WP_001006717.1 hypothetical protein -
H9207_RS24075 (H9207_23860) 122924..123475 - 552 WP_000662998.1 hypothetical protein -
H9207_RS24080 (H9207_23865) 123535..123771 - 237 WP_000792381.1 hypothetical protein -
H9207_RS24085 (H9207_23870) 123830..124345 - 516 WP_001025390.1 DnaJ domain-containing protein -
H9207_RS24090 (H9207_23875) 124935..125087 - 153 Protein_120 DNA-binding protein -
H9207_RS24095 (H9207_23880) 125698..126711 + 1014 WP_001348704.1 replication initiation protein -
H9207_RS24100 (H9207_23885) 126720..127163 + 444 WP_001074369.1 hypothetical protein -
H9207_RS24105 (H9207_23890) 127351..127704 + 354 WP_000877224.1 DNA distortion polypeptide 3 -
H9207_RS24110 (H9207_23895) 127725..128009 - 285 WP_001043731.1 hypothetical protein -
H9207_RS24115 (H9207_23900) 128045..128356 - 312 WP_000469598.1 hypothetical protein -
H9207_RS24120 (H9207_23905) 128562..128846 - 285 WP_001185481.1 hypothetical protein -
H9207_RS24125 (H9207_23910) 128946..129608 - 663 WP_000516402.1 division plane positioning ATPase MipZ -
H9207_RS24130 (H9207_23915) 129989..130651 + 663 WP_001549893.1 Tn3 family transposase TnpR_TnEc1 Transposase
H9207_RS24135 (H9207_23920) 130740..131960 - 1221 WP_000343760.1 ISL3 family transposase ISKox3 Transposase
H9207_RS24140 (H9207_23925) 132062..132301 + 240 WP_001549892.1 hypothetical protein -
H9207_RS24145 132304..132660 + 357 WP_004199403.1 hypothetical protein -
H9207_RS24150 (H9207_23930) 132694..133398 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
H9207_RS24155 (H9207_23935) 134833..136040 + 1208 WP_089617520.1 IS3 family transposase ISEcl1 Transposase
H9207_RS24160 136037..136621 - 585 WP_224672773.1 RepA protein -
H9207_RS24165 (H9207_23945) 136894..138612 - 1719 WP_000739198.1 hybrid sensor histidine kinase/response regulator -
H9207_RS24170 (H9207_23950) 138609..139097 - 489 WP_000238872.1 molybdopterin-dependent oxidoreductase -
H9207_RS24175 (H9207_23955) 139090..140073 - 984 WP_072851549.1 hypothetical protein -
H9207_RS24180 (H9207_23960) 140077..140991 - 915 WP_000891983.1 helix-turn-helix domain-containing protein -
H9207_RS24185 (H9207_23965) 141305..141613 + 309 WP_000062770.1 hypothetical protein -
H9207_RS24190 (H9207_23970) 141606..141821 + 216 WP_001112907.1 hypothetical protein -
H9207_RS24195 (H9207_23975) 141824..142486 + 663 WP_000958205.1 Type IV secretion system protein virB1 VF
H9207_RS24200 (H9207_23980) 142497..142796 + 300 WP_000175462.1 TrbC/VirB2 family protein -
H9207_RS24205 (H9207_23985) 142806..145556 + 2751 WP_063078619.1 Type IV secretion system protein virB4 VF
H9207_RS24210 (H9207_23990) 145575..146291 + 717 WP_000770034.1 type IV secretion system protein -
H9207_RS24215 (H9207_23995) 146303..146587 + 285 WP_000769859.1 EexN family lipoprotein -
H9207_RS24220 (H9207_24000) 146605..147612 + 1008 WP_000014166.1 type IV secretion system protein -
H9207_RS24225 (H9207_24005) 147689..147829 + 141 WP_000873539.1 hypothetical protein -
H9207_RS24230 (H9207_24010) 147822..148508 + 687 WP_072851547.1 type IV secretion system protein -
H9207_RS24235 (H9207_24015) 148501..149394 + 894 WP_001045307.1 P-type conjugative transfer protein VirB9 -
H9207_RS24240 (H9207_24020) 149391..150587 + 1197 WP_094885502.1 Type IV secretion system protein virB10 VF
H9207_RS24245 (H9207_24025) 150591..151640 + 1050 WP_072851541.1 Type IV secretion system protein VirB11 VF
H9207_RS24250 (H9207_24030) 151627..152028 + 402 WP_000979494.1 cag pathogenicity island Cag12 family protein -
H9207_RS24255 (H9207_24035) 152119..152436 + 318 WP_000683352.1 TrbM/KikA/MpfK family conjugal transfer protein -
H9207_RS24260 (H9207_24040) 152463..152798 + 336 WP_000610141.1 hypothetical protein -
H9207_RS24265 (H9207_24045) 152774..153082 + 309 WP_000212005.1 hypothetical protein -
H9207_RS24270 (H9207_24050) 153079..155280 + 2202 WP_072851538.1 type IA DNA topoisomerase -
H9207_RS24275 (H9207_24055) 155277..155669 + 393 WP_001079960.1 H-NS family nucleoid-associated regulatory protein -
H9207_RS24280 (H9207_24060) 156378..158285 + 1908 WP_072851534.1 type IV secretion system DNA-binding domain-containing protein -
H9207_RS24285 (H9207_24065) 158300..159046 + 747 WP_072851531.1 MobC family replication-relaxation protein -
H9207_RS24290 (H9207_24070) 159039..159566 + 528 WP_072851528.1 Phospholipase D VF
H9207_RS24295 (H9207_24075) 159597..160028 - 432 WP_001776120.1 hypothetical protein -
H9207_RS24300 (H9207_24080) 160160..160336 - 177 WP_013438824.1 hypothetical protein -
H9207_RS24305 (H9207_24085) 160508..161473 - 966 WP_077252056.1 zincin-like metallopeptidase domain-containing protein -
H9207_RS24310 (H9207_24090) 161925..162350 + 426 WP_001776124.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
H9207_RS24315 (H9207_24095) 162350..163621 + 1272 WP_072851522.1 Y-family DNA polymerase -
H9207_RS24320 (H9207_24100) 163700..163951 + 252 WP_000181753.1 hypothetical protein -
H9207_RS24325 (H9207_24105) 164005..164310 + 306 WP_000534920.1 hypothetical protein -
H9207_RS24330 (H9207_24110) 165344..166315 - 972 WP_000817037.1 ParB/RepB/Spo0J family plasmid partition protein -
H9207_RS24335 (H9207_24115) 166315..167481 - 1167 WP_063501643.1 Sporulation initiation inhibitor protein Soj VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance