MGE detailed information
MGE type: Conjugative plasmid MGE length: 111136 bp
Accession: NZ_CP060283 Location: 1..111136 Organism: Klebsiella pneumoniae strain ent1077 Replicon: plasmid pMDR
Accession: NZ_CP060283 Location: 1..111136 Organism: Klebsiella pneumoniae strain ent1077 Replicon: plasmid pMDR
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| H7U30_RS27335 () | 1..1014 | + | 1014 | WP_015065551.1 | replication protein | - |
| H7U30_RS27340 () | 1999..2334 | - | 336 | WP_011977766.1 | C2H2-type zinc finger protein | - |
| H7U30_RS27345 () | 2507..2788 | + | 282 | WP_001568067.1 | hypothetical protein | - |
| H7U30_RS27350 () | 2842..3453 | + | 612 | WP_000176305.1 | DUF2913 family protein | - |
| H7U30_RS27355 () | 3450..3611 | - | 162 | WP_001326844.1 | hypothetical protein | - |
| H7U30_RS27360 () | 3638..4630 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| H7U30_RS27365 () | 4679..4834 | - | 156 | WP_000075580.1 | hypothetical protein | - |
| H7U30_RS27370 () | 4975..5679 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H7U30_RS27375 () | 5714..5899 | - | 186 | Protein_9 | IS1 family transposase | - |
| H7U30_RS27380 () | 6028..7431 | + | 1404 | WP_072094655.1 | DNA cytosine methyltransferase | - |
| H7U30_RS27385 () | 7465..8679 | - | 1215 | WP_004098817.1 | type II site-specific deoxyribonuclease | - |
| H7U30_RS27390 () | 8735..8800 | + | 66 | Protein_12 | EAL domain-containing protein | - |
| H7U30_RS27395 () | 8940..9704 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| H7U30_RS27400 () | 9847..10113 | - | 267 | WP_001144737.1 | hypothetical protein | Relaxase |
| H7U30_RS27405 () | 10334..10807 | - | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| H7U30_RS27410 () | 10963..11976 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| H7U30_RS27415 () | 12522..13226 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H7U30_RS27420 () | 13276..14007 | + | 732 | Protein_18 | putative oxidoreductase YghA | VF |
| H7U30_RS27425 () | 14099..14743 | - | 645 | WP_014386481.1 | Pentapeptide repeat protein | ARG |
| H7U30_RS27430 () | 14837..15238 | - | 402 | Protein_20 | phage shock protein operon transcriptional activator | - |
| H7U30_RS27435 () | 15314..17116 | - | 1803 | Protein_21 | Tn3 family transposase TnpA_IS3000 | Transposase |
| H7U30_RS27440 () | 17151..20048 | - | 2898 | WP_001553819.1 | Tn3 family transposase TnpA_Tn5403 | Transposase |
| H7U30_RS27445 () | 20143..20748 | + | 606 | WP_000509965.1 | Tn3 family transposase TnpR_Tn5403 | Transposase |
| H7U30_RS27450 () | 20772..21521 | - | 750 | Protein_24 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| H7U30_RS27455 () | 21510..21917 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| H7U30_RS27460 () | 22055..22939 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| H7U30_RS27465 () | 22971..24170 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| H7U30_RS27470 () | 24276..24926 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| H7U30_RS27475 () | 24958..25200 | - | 243 | WP_032140899.1 | hypothetical protein | - |
| H7U30_RS27480 () | 25242..26756 | - | 1515 | Protein_30 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| H7U30_RS27485 () | 26822..27526 | + | 705 | WP_004186977.1 | IS6 family transposase IS26 | Transposase |
| H7U30_RS27490 () | 27580..28677 | + | 1098 | Protein_32 | IS66 family transposase ISPsy43 | Transposase |
| H7U30_RS27495 () | 28928..29491 | - | 564 | WP_001097412.1 | chlorite dismutase family protein | - |
| H7U30_RS27500 () | 29515..29889 | - | 375 | WP_001348195.1 | cupin domain-containing protein | - |
| H7U30_RS27505 () | 29954..30517 | - | 564 | WP_001515734.1 | IS66 family transposase ISPpu15 | Transposase |
| H7U30_RS27510 () | 30760..31095 | + | 336 | WP_000046891.1 | thermonuclease family protein | - |
| H7U30_RS27515 () | 31968..32168 | + | 201 | Protein_37 | IS6 family transposase IS15 | Transposase |
| H7U30_RS27520 () | 32220..32924 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| H7U30_RS27525 () | 32980..33378 | + | 399 | Protein_39 | recombinase family protein | - |
| H7U30_RS27530 () | 33425..34075 | + | 651 | WP_015065500.1 | SOS response-associated peptidase | - |
| H7U30_RS27535 () | 34372..35367 | + | 996 | WP_019725651.1 | hypothetical protein | - |
| H7U30_RS27540 () | 35440..35763 | + | 324 | WP_019725650.1 | hypothetical protein | - |
| H7U30_RS27545 () | 36197..36391 | + | 195 | WP_019725033.1 | hypothetical protein | - |
| H7U30_RS27550 () | 36435..36665 | - | 231 | WP_019725034.1 | hypothetical protein | - |
| H7U30_RS27555 () | 36679..36882 | - | 204 | WP_019725040.1 | hemolysin expression modulator Hha | - |
| H7U30_RS27560 () | 36916..37284 | - | 369 | WP_015065502.1 | hypothetical protein | - |
| H7U30_RS27565 () | 37328..37822 | - | 495 | WP_009310053.1 | hypothetical protein | - |
| H7U30_RS27570 () | 37853..38425 | - | 573 | WP_015065504.1 | hypothetical protein | - |
| H7U30_RS27575 () | 38422..38670 | - | 249 | WP_019725036.1 | hypothetical protein | - |
| H7U30_RS27580 () | 39266..39484 | + | 219 | WP_004197642.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| H7U30_RS27585 () | 39486..39791 | + | 306 | WP_004197633.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| H7U30_RS27590 () | 39960..40361 | + | 402 | WP_072199347.1 | hypothetical protein | - |
| H7U30_RS27595 () | 40388..40711 | + | 324 | WP_004197641.1 | hypothetical protein | - |
| H7U30_RS27600 () | 40708..41724 | + | 1017 | WP_004197639.1 | hypothetical protein | - |
| H7U30_RS27605 () | 41922..42716 | + | 795 | WP_004197635.1 | site-specific integrase | - |
| H7U30_RS27610 () | 43172..43351 | - | 180 | WP_006788217.1 | hypothetical protein | - |
| H7U30_RS27615 () | 43471..44097 | - | 627 | WP_004197649.1 | Chromosome-partitioning ATPase Soj | VF |
| H7U30_RS27620 () | 44714..45589 | - | 876 | WP_004197644.1 | RepB family plasmid replication initiator protein | - |
| H7U30_RS27625 () | 46001..47272 | - | 1272 | WP_004197646.1 | Y-family DNA polymerase | - |
| H7U30_RS27630 () | 47272..47703 | - | 432 | WP_004152352.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| H7U30_RS27635 () | 47935..48906 | + | 972 | WP_004152353.1 | mediator of plasmid stability | - |
| H7U30_RS27640 () | 48909..49580 | + | 672 | WP_004152354.1 | plasmid partitioning/stability family protein | - |
| H7U30_RS27645 () | 49641..49871 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| H7U30_RS27650 () | 50308..51009 | + | 702 | WP_004152355.1 | DNA methylase | - |
| H7U30_RS27655 () | 51009..51230 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| H7U30_RS27660 () | 51240..51659 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| H7U30_RS27665 () | 51713..52480 | + | 768 | WP_001568044.1 | hypothetical protein | - |
| H7U30_RS27670 () | 53160..53588 | + | 429 | WP_023279469.1 | antirestriction protein | - |
| H7U30_RS27675 () | 53631..54137 | + | 507 | WP_015065510.1 | antirestriction protein ArdA | - |
| H7U30_RS27680 () | 54180..54371 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| H7U30_RS27685 () | 54559..54813 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| H7U30_RS27690 () | 54848..55168 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| H7U30_RS27695 () | 55847..56074 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| H7U30_RS27700 () | 56166..56396 | + | 231 | WP_009310031.1 | hypothetical protein | - |
| H7U30_RS27705 () | 56448..57803 | + | 1356 | WP_015065512.1 | DUF3560 domain-containing protein | - |
| H7U30_RS27710 () | 57851..58414 | + | 564 | WP_004152756.1 | methyltransferase | - |
| H7U30_RS27715 () | 59245..59787 | + | 543 | WP_015065513.1 | single-stranded DNA-binding protein | - |
| H7U30_RS27720 () | 59836..60084 | + | 249 | WP_009310026.1 | DUF905 domain-containing protein | - |
| H7U30_RS27725 () | 60154..62211 | + | 2058 | WP_015065514.1 | ParB/RepB/Spo0J family partition protein | - |
| H7U30_RS27730 () | 62256..62687 | + | 432 | WP_015065515.1 | conjugation system SOS inhibitor PsiB | - |
| H7U30_RS27735 () | 62684..63412 | + | 729 | WP_015065516.1 | plasmid SOS inhibition protein A | - |
| H7U30_RS27740 () | 63409..63735 | + | 327 | WP_015065517.1 | hypothetical protein | - |
| H7U30_RS27745 () | 63791..64165 | + | 375 | WP_023287106.1 | hypothetical protein | - |
| H7U30_RS27750 () | 64421..64579 | + | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| H7U30_RS27755 () | 65273..65545 | + | 273 | WP_023287105.1 | hypothetical protein | - |
| H7U30_RS27760 () | 65542..65892 | + | 351 | WP_032330277.1 | hypothetical protein | - |
| H7U30_RS27765 () | 65907..66224 | + | 318 | WP_015065519.1 | hypothetical protein | - |
| H7U30_RS27770 () | 67065..67421 | + | 357 | WP_019706019.1 | hypothetical protein | - |
| H7U30_RS27775 () | 67482..67694 | + | 213 | WP_019706020.1 | hypothetical protein | - |
| H7U30_RS27780 () | 67705..67929 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| H7U30_RS27785 () | 68010..68330 | + | 321 | WP_015065521.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| H7U30_RS27790 () | 68320..68598 | + | 279 | WP_020801586.1 | helix-turn-helix domain-containing protein | - |
| H7U30_RS27795 () | 68599..69000 | + | 402 | WP_015065522.1 | helix-turn-helix domain-containing protein | - |
| H7U30_RS27800 () | 69829..70651 | + | 823 | Protein_94 | DUF945 domain-containing protein | - |
| H7U30_RS27805 () | 70684..71013 | + | 330 | WP_015065524.1 | hypothetical protein | - |
| H7U30_RS27810 () | 71046..71531 | - | 486 | WP_015065525.1 | hypothetical protein | VF |
| H7U30_RS27815 () | 71922..72338 | + | 417 | WP_072145360.1 | relaxosome protein TraM | - |
| H7U30_RS27820 () | 72538..73257 | + | 720 | WP_015065526.1 | hypothetical protein | - |
| H7U30_RS27825 () | 73390..73593 | + | 204 | WP_171486139.1 | TraY domain-containing protein | - |
| H7U30_RS27830 () | 73658..74026 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| H7U30_RS27835 () | 74040..74345 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| H7U30_RS27840 () | 74365..74931 | + | 567 | WP_004144423.1 | type IV conjugative transfer system protein TraE | - |
| H7U30_RS27845 () | 74918..75658 | + | 741 | WP_013214019.1 | type-F conjugative transfer system secretin TraK | - |
| H7U30_RS27850 () | 75658..77082 | + | 1425 | WP_004155033.1 | conjugal transfer protein TraB | - |
| H7U30_RS27855 () | 77196..77780 | + | 585 | WP_004161368.1 | type IV conjugative transfer system lipoprotein TraV | - |
| H7U30_RS27860 () | 77912..78322 | + | 411 | WP_004152499.1 | hypothetical protein | - |
| H7U30_RS27865 () | 78428..78646 | + | 219 | WP_004152501.1 | hypothetical protein | - |
| H7U30_RS27870 () | 78647..78958 | + | 312 | WP_004152502.1 | hypothetical protein | - |
| H7U30_RS27875 () | 79025..79429 | + | 405 | WP_004152503.1 | hypothetical protein | - |
| H7U30_RS27880 () | 79472..79861 | + | 390 | WP_004153076.1 | hypothetical protein | - |
| H7U30_RS27885 () | 79869..80267 | + | 399 | WP_011977783.1 | hypothetical protein | - |
| H7U30_RS27890 () | 80339..82978 | + | 2640 | WP_004152505.1 | type IV secretion system protein TraC | - |
| H7U30_RS27895 () | 82978..83367 | + | 390 | WP_004152506.1 | type-F conjugative transfer system protein TrbI | - |
| H7U30_RS27900 () | 83367..83993 | + | 627 | WP_004152507.1 | type-F conjugative transfer system protein TraW | - |
| H7U30_RS27905 () | 84035..84424 | + | 390 | WP_004152508.1 | hypothetical protein | - |
| H7U30_RS27910 () | 84421..85410 | + | 990 | WP_011977785.1 | conjugal transfer pilus assembly protein TraU | - |
| H7U30_RS27915 () | 85423..86061 | + | 639 | WP_011977786.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| H7U30_RS27920 () | 86120..88075 | + | 1956 | WP_004152673.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| H7U30_RS27925 () | 88107..88361 | + | 255 | WP_004152674.1 | conjugal transfer protein TrbE | - |
| H7U30_RS27930 () | 88339..88587 | + | 249 | WP_004152675.1 | hypothetical protein | - |
| H7U30_RS27935 () | 88600..88926 | + | 327 | WP_004152676.1 | hypothetical protein | - |
| H7U30_RS27940 () | 88947..89699 | + | 753 | WP_004152677.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| H7U30_RS27945 () | 89710..89949 | + | 240 | WP_004144400.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| H7U30_RS27950 () | 89921..90478 | + | 558 | WP_013214031.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| H7U30_RS27955 () | 90524..90967 | + | 444 | WP_004152679.1 | F-type conjugal transfer protein TrbF | - |
| H7U30_RS27960 () | 90945..92324 | + | 1380 | WP_011977731.1 | conjugal transfer protein TraH | - |
| H7U30_RS27965 () | 92324..95173 | + | 2850 | WP_004152624.1 | conjugal transfer mating pair stabilization protein TraG | - |
| H7U30_RS27970 () | 95186..95734 | + | 549 | WP_004152623.1 | conjugal transfer entry exclusion protein TraS | - |
| H7U30_RS27975 () | 95918..96649 | + | 732 | WP_004152622.1 | complement resistance protein TraT | - |
| H7U30_RS27980 () | 96841..97530 | + | 690 | WP_015065540.1 | hypothetical protein | - |
| H7U30_RS27985 () | 97659..99971 | + | 2313 | Protein_131 | type IV conjugative transfer system coupling protein TraD | - |
| H7U30_RS27990 () | 99971..105229 | + | 5259 | WP_149998655.1 | Multifunctional conjugation protein TraI | Relaxase |
| H7U30_RS27995 () | 105309..106034 | + | 726 | WP_015065543.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| H7U30_RS28000 () | 106190..106783 | + | 594 | WP_015065544.1 | fertility inhibition protein FinO | - |
| H7U30_RS28005 () | 106944..107546 | + | 603 | WP_015065545.1 | hypothetical protein | - |
| H7U30_RS28010 () | 107596..108240 | + | 645 | WP_015065546.1 | hypothetical protein | - |
| H7U30_RS28015 () | 108296..108946 | + | 651 | WP_022631529.1 | DUF2726 domain-containing protein | - |
| H7U30_RS28020 () | 108943..109251 | + | 309 | WP_015065549.1 | hypothetical protein | - |
| H7U30_RS28025 () | 109427..109906 | + | 480 | WP_023157996.1 | Phospholipase D | VF |
| H7U30_RS28030 () | 110042..110311 | + | 270 | WP_022631531.1 | replication regulatory protein RepA | - |
| H7U30_RS28035 () | 110523..110600 | + | 78 | WP_014386216.1 | RepA leader peptide Tap | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|