MGE detailed information
MGE type: Mobilizable plasmid MGE length: 86483 bp
Accession: NZ_CP058832 Location: 1..86483 Organism: Shigella flexneri strain STLE4 Replicon: plasmid unnamed1
Accession: NZ_CP058832 Location: 1..86483 Organism: Shigella flexneri strain STLE4 Replicon: plasmid unnamed1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HZT21_RS22605 (HZT21_22405) | 1..978 | + | 978 | WP_000361612.1 | RepB family plasmid replication initiator protein | - |
| HZT21_RS22610 (HZT21_22410) | 1257..1997 | - | 741 | WP_063090490.1 | IS91 family transposase ISMno23 | Transposase |
| HZT21_RS22620 (HZT21_22420) | 3333..3962 | - | 630 | Protein_3 | IS6 family transposase IS15DI | Transposase |
| HZT21_RS22625 (HZT21_22425) | 4026..4166 | - | 141 | Protein_4 | RNA polymerase sigma factor FecI | - |
| HZT21_RS22630 | 4303..4371 | + | 69 | WP_211180522.1 | protein YkiE | - |
| HZT21_RS22635 (HZT21_22430) | 4458..5155 | + | 698 | WP_232585763.1 | IS1 family transposase | - |
| HZT21_RS22640 (HZT21_22435) | 5531..6307 | + | 777 | WP_022631027.1 | MBL fold metallo-hydrolase | - |
| HZT21_RS22645 (HZT21_22440) | 6323..7312 | + | 990 | WP_001541953.1 | HTH-type transcriptional regulator CdhR | VF |
| HZT21_RS22650 (HZT21_22445) | 7321..7746 | + | 426 | WP_063072980.1 | ester cyclase | - |
| HZT21_RS22655 (HZT21_22450) | 7941..8045 | + | 105 | Protein_10 | IS3 family transposase | - |
| HZT21_RS22660 (HZT21_22455) | 8349..8642 | + | 294 | WP_223429961.1 | biofilm development regulator YmgB/AriR family protein | - |
| HZT21_RS22665 | 8767..8903 | - | 137 | Protein_12 | IS5/IS1182 family transposase | - |
| HZT21_RS23265 (HZT21_22460) | 8980..9114 | - | 135 | WP_257187774.1 | hypothetical protein | - |
| HZT21_RS22670 (HZT21_22465) | 9170..9448 | - | 279 | WP_244578848.1 | type II toxin-antitoxin system toxin YacB | Toxin Detail |
| HZT21_RS22675 (HZT21_22470) | 9448..9717 | - | 270 | WP_000079938.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin Detail |
| HZT21_RS22680 (HZT21_22475) | 9790..9930 | - | 141 | WP_160784086.1 | hypothetical protein | - |
| HZT21_RS22685 (HZT21_22480) | 10190..10471 | + | 282 | WP_224732584.1 | Tn3 family transposase | - |
| HZT21_RS22690 (HZT21_22485) | 10670..11674 | - | 1005 | WP_000427623.1 | IS110 family transposase IS4321R | Transposase |
| HZT21_RS22695 (HZT21_22490) | 12092..13528 | - | 1437 | WP_000105383.1 | glutathione synthase | - |
| HZT21_RS22700 (HZT21_22495) | 13795..14499 | + | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HZT21_RS22705 (HZT21_22500) | 14554..15183 | + | 630 | Protein_21 | IS6 family transposase IS15DI | Transposase |
| HZT21_RS22710 (HZT21_22505) | 15237..15572 | + | 336 | Protein_22 | bleomycin binding protein | - |
| HZT21_RS22715 (HZT21_22510) | 15892..16284 | - | 393 | WP_000084745.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| HZT21_RS22720 | 16536..16622 | - | 87 | Protein_24 | hypothetical protein | - |
| HZT21_RS22725 (HZT21_22515) | 16722..17560 | - | 839 | Protein_25 | Streptomycin 3''-adenylyltransferase | ARG |
| HZT21_RS22730 (HZT21_22520) | 17566..17856 | - | 291 | WP_001336345.1 | DUF1010 domain-containing protein | - |
| HZT21_RS22735 (HZT21_22525) | 17968..18465 | - | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| HZT21_RS22740 (HZT21_22530) | 18610..19623 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| HZT21_RS22745 (HZT21_22535) | 19758..20462 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HZT21_RS22750 (HZT21_22540) | 20499..21626 | - | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| HZT21_RS22755 (HZT21_22545) | 21677..21904 | - | 228 | WP_000248278.1 | hypothetical protein | - |
| HZT21_RS22760 (HZT21_22550) | 21928..22119 | + | 192 | WP_000951934.1 | hypothetical protein | - |
| HZT21_RS22765 (HZT21_22555) | 22601..23143 | - | 543 | WP_000587837.1 | AAA family ATPase | - |
| HZT21_RS22770 (HZT21_22560) | 23156..24016 | - | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| HZT21_RS22775 (HZT21_22565) | 24159..25121 | + | 963 | Protein_35 | IS4 family transposase IS10R | Transposase |
| HZT21_RS22780 (HZT21_22570) | 25231..25917 | + | 687 | Protein_36 | IS4 family transposase IS10R | Transposase |
| HZT21_RS22785 (HZT21_22575) | 25971..26675 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HZT21_RS22790 (HZT21_22580) | 26739..26819 | - | 81 | Protein_38 | IS6 family transposase | - |
| HZT21_RS22795 (HZT21_22585) | 27139..28314 | + | 1176 | WP_002914189.1 | Efflux pump periplasmic linker BepF | VF |
| HZT21_RS22800 (HZT21_22590) | 28338..31490 | + | 3153 | WP_000347934.1 | Efflux pump membrane transporter BepE | VF |
| HZT21_RS22805 (HZT21_22595) | 31560..32039 | - | 480 | WP_000888203.1 | Rrf2 family transcriptional regulator | - |
| HZT21_RS22810 (HZT21_22600) | 32141..32845 | - | 705 | WP_101973398.1 | IS6 family transposase IS15DI | Transposase |
| HZT21_RS22815 (HZT21_22605) | 32956..33342 | - | 387 | WP_240763341.1 | plasmid stabilization protein StbA | - |
| HZT21_RS22820 (HZT21_22610) | 33924..34157 | + | 234 | Protein_44 | transposase | - |
| HZT21_RS22825 (HZT21_22615) | 34190..35941 | - | 1752 | Protein_45 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HZT21_RS22830 (HZT21_22620) | 35945..36337 | + | 393 | WP_001351729.1 | isochorismatase family cysteine hydrolase | - |
| HZT21_RS22835 (HZT21_22625) | 36475..37359 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| HZT21_RS22840 (HZT21_22630) | 37391..38590 | - | 1200 | WP_025732387.1 | Tetracycline resistance protein, class C | ARG |
| HZT21_RS22845 (HZT21_22635) | 38696..39322 | + | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| HZT21_RS22850 (HZT21_22640) | 39354..39596 | - | 243 | WP_000844627.1 | transposase | - |
| HZT21_RS22855 (HZT21_22645) | 39902..40738 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| HZT21_RS22860 (HZT21_22650) | 40738..41541 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| HZT21_RS22865 (HZT21_22655) | 41602..42417 | - | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| HZT21_RS22870 (HZT21_22660) | 42579..43439 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| HZT21_RS22875 (HZT21_22665) | 43622..44179 | - | 558 | WP_001217881.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HZT21_RS22880 (HZT21_22670) | 44341..47346 | + | 3006 | WP_001143775.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HZT21_RS22885 (HZT21_22675) | 47411..48037 | - | 627 | WP_031606906.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| HZT21_RS22890 (HZT21_22680) | 48143..49342 | + | 1200 | WP_063097389.1 | Tetracycline resistance protein, class C | ARG |
| HZT21_RS22895 (HZT21_22685) | 49309..49497 | - | 189 | Protein_59 | IS91 family transposase | - |
| HZT21_RS22900 (HZT21_22690) | 49609..49914 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| HZT21_RS22905 (HZT21_22695) | 49942..51156 | - | 1215 | WP_000214121.1 | Bicyclomycin resistance protein | ARG |
| HZT21_RS22910 (HZT21_22700) | 51373..52257 | - | 885 | WP_001447541.1 | DUF3363 domain-containing protein | - |
| HZT21_RS22915 (HZT21_22705) | 52288..53781 | - | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| HZT21_RS22920 (HZT21_22710) | 53992..54216 | - | 225 | WP_000743213.1 | hypothetical protein | - |
| HZT21_RS22925 (HZT21_22715) | 54213..54950 | - | 738 | WP_001366550.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| HZT21_RS22930 (HZT21_22720) | 55436..55576 | - | 141 | WP_001044210.1 | hypothetical protein | - |
| HZT21_RS22935 (HZT21_22725) | 55582..56286 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HZT21_RS22940 (HZT21_22730) | 56359..56577 | + | 219 | Protein_68 | IS1 family transposase | - |
| HZT21_RS22945 (HZT21_22735) | 56571..56879 | - | 309 | WP_025670887.1 | DUF305 domain-containing protein | - |
| HZT21_RS22950 (HZT21_22740) | 57023..57454 | - | 432 | WP_000790483.1 | silver-binding protein SilE | - |
| HZT21_RS22955 (HZT21_22745) | 57705..59180 | - | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| HZT21_RS22960 (HZT21_22750) | 59173..59853 | - | 681 | WP_000697969.1 | Transcriptional regulatory protein CusR | VF |
| HZT21_RS22965 (HZT21_22755) | 60043..61428 | + | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| HZT21_RS22970 (HZT21_22760) | 61456..61809 | + | 354 | WP_001246155.1 | cation efflux system protein CusF | - |
| HZT21_RS22975 (HZT21_22765) | 61923..63215 | + | 1293 | WP_001381488.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| HZT21_RS22980 (HZT21_22770) | 63226..66372 | + | 3147 | WP_020219104.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| HZT21_RS22985 (HZT21_22775) | 66459..66899 | + | 441 | WP_000758229.1 | DUF411 domain-containing protein | - |
| HZT21_RS22990 (HZT21_22780) | 66997..69474 | + | 2478 | WP_001398208.1 | Ag(+)-translocating P-type ATPase SilP | - |
| HZT21_RS22995 (HZT21_22785) | 69515..69712 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| HZT21_RS23000 (HZT21_22790) | 69746..70021 | - | 276 | Protein_80 | peptidoglycan DD-metalloendopeptidase family protein | - |
| HZT21_RS23005 (HZT21_22795) | 70056..71024 | + | 969 | WP_077783444.1 | IS5 family transposase IS903B | Transposase |
| HZT21_RS23010 (HZT21_22800) | 71061..71318 | - | 258 | WP_105278499.1 | hypothetical protein | - |
| HZT21_RS23015 (HZT21_22805) | 71464..71694 | - | 231 | Protein_83 | IS1 family transposase | - |
| HZT21_RS23020 (HZT21_22810) | 71745..72449 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HZT21_RS23025 (HZT21_22815) | 72531..72803 | - | 273 | Protein_85 | IS1 family transposase IS1X2 | Transposase |
| HZT21_RS23030 (HZT21_22820) | 72897..74330 | + | 1434 | WP_001288435.1 | DNA cytosine methyltransferase | - |
| HZT21_RS23035 (HZT21_22825) | 74364..75578 | - | 1215 | WP_001532073.1 | type II site-specific deoxyribonuclease | - |
| HZT21_RS23040 (HZT21_22830) | 75934..76638 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HZT21_RS23045 (HZT21_22835) | 76698..78407 | - | 1710 | Protein_89 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| HZT21_RS23050 (HZT21_22840) | 78410..78631 | - | 222 | Protein_90 | recombinase family protein | - |
| HZT21_RS23055 (HZT21_22845) | 78697..79401 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HZT21_RS23060 | 79455..79529 | - | 75 | Protein_92 | hypothetical protein | - |
| HZT21_RS23065 (HZT21_22850) | 80513..80704 | - | 192 | WP_032200969.1 | hypothetical protein | - |
| HZT21_RS23070 | 80701..81154 | - | 454 | Protein_94 | hypothetical protein | - |
| HZT21_RS23075 (HZT21_22865) | 81154..81579 | - | 426 | WP_063090491.1 | antirestriction protein | - |
| HZT21_RS23080 (HZT21_22870) | 81653..81826 | + | 174 | Protein_96 | DUF4113 domain-containing protein | - |
| HZT21_RS23085 (HZT21_22875) | 81967..82929 | - | 963 | WP_032200967.1 | ParB family protein | - |
| HZT21_RS23090 (HZT21_22880) | 82926..84131 | - | 1206 | WP_000817642.1 | Plasmid partition protein A | VF |
| HZT21_RS23095 (HZT21_22885) | 84506..84718 | + | 213 | WP_000402944.1 | hypothetical protein | - |
| HZT21_RS23100 (HZT21_22890) | 84892..85143 | + | 252 | WP_001132895.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| HZT21_RS23105 (HZT21_22895) | 85140..85427 | + | 288 | WP_001270421.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HZT21_RS23110 (HZT21_22900) | 85429..85840 | + | 412 | Protein_102 | DDE-type integrase/transposase/recombinase | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|