MGE detailed information

MGE type: Conjugative plasmid        MGE length: 161606 bp
Accession: NZ_CP058359        Location: 1..161606         Organism: Klebsiella pneumoniae strain KP486       Replicon: plasmid unnamed1


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYD35_RS26665 (HYD35_26655) 1..1011 + 1011 WP_023328265.1 RepB family plasmid replication initiator protein -
HYD35_RS26670 (HYD35_26660) 1729..2469 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
HYD35_RS26675 (HYD35_26665) 3613..4560 + 948 WP_023328266.1 sensor domain-containing diguanylate cyclase -
HYD35_RS26680 (HYD35_26670) 4587..6470 - 1884 WP_077269298.1 putative signaling protein VF
HYD35_RS26685 (HYD35_26675) 6991..7113 + 123 WP_139788384.1 small membrane protein -
HYD35_RS26690 (HYD35_26680) 7404..8039 + 636 WP_064185732.1 hypothetical protein -
HYD35_RS26695 (HYD35_26685) 8339..8812 + 474 WP_131863819.1 LuxR C-terminal-related transcriptional regulator -
HYD35_RS26700 (HYD35_26690) 9339..9596 - 258 WP_023328269.1 hypothetical protein -
HYD35_RS28330 10074..10802 + 729 Protein_8 putative cyclic di-GMP phosphodiesterase PdeB VF
HYD35_RS28335 10854..11654 + 801 WP_049183813.1 putative cyclic di-GMP phosphodiesterase PdeB VF
HYD35_RS26710 (HYD35_26700) 12185..12718 - 534 WP_023328271.1 hypothetical protein -
HYD35_RS26715 (HYD35_26705) 12770..13120 - 351 WP_023328272.1 hypothetical protein -
HYD35_RS26720 (HYD35_26710) 13309..13507 - 199 Protein_12 hypothetical protein -
HYD35_RS26725 (HYD35_26715) 13686..14660 - 975 WP_023328273.1 sensor domain-containing diguanylate cyclase -
HYD35_RS26730 (HYD35_26720) 15297..16205 + 909 WP_001372261.1 HNH endonuclease -
HYD35_RS26735 (HYD35_26725) 16593..16943 - 351 WP_023328274.1 DUF305 domain-containing protein -
HYD35_RS26740 (HYD35_26730) 17087..17518 - 432 WP_000790483.1 silver-binding protein SilE -
HYD35_RS26745 (HYD35_26735) 17769..19244 - 1476 WP_000555737.1 copper/silver sensor histidine kinase SilS -
HYD35_RS26750 (HYD35_26740) 19237..19917 - 681 WP_000697969.1 Transcriptional regulatory protein CusR VF
HYD35_RS26755 (HYD35_26745) 20107..21492 + 1386 WP_000475503.1 Cation efflux system protein CusC VF
HYD35_RS26760 (HYD35_26750) 21521..21874 + 354 WP_001246153.1 cation efflux system protein CusF -
HYD35_RS26765 (HYD35_26755) 21988..23280 + 1293 WP_004098959.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
HYD35_RS26770 (HYD35_26760) 23291..26437 + 3147 WP_004098958.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
HYD35_RS26775 (HYD35_26765) 26524..26964 + 441 WP_000758228.1 DUF411 domain-containing protein -
HYD35_RS26780 (HYD35_26770) 27091..29538 + 2448 WP_004098955.1 Ag(+)-translocating P-type ATPase SilP -
HYD35_RS26785 (HYD35_26775) 29579..29830 + 252 WP_023328275.1 DUF2933 domain-containing protein -
HYD35_RS26790 (HYD35_26780) 29809..30546 - 738 WP_004182013.1 Murein DD-endopeptidase MepM VF
HYD35_RS26795 (HYD35_26785) 30835..31284 - 450 WP_001023257.1 copper resistance protein -
HYD35_RS26800 (HYD35_26790) 31518..33335 + 1818 WP_000925242.1 multicopper oxidase PcoA -
HYD35_RS26805 (HYD35_26795) 33341..34231 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
HYD35_RS26810 (HYD35_26800) 34271..34651 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
HYD35_RS26815 (HYD35_26805) 34656..35585 + 930 WP_023328276.1 copper resistance inner membrane protein PcoD -
HYD35_RS26820 (HYD35_26810) 35640..36320 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
HYD35_RS26825 (HYD35_26815) 36317..37717 + 1401 WP_004152084.1 copper resistance membrane spanning protein PcoS -
HYD35_RS26830 (HYD35_26820) 37934..38368 + 435 WP_004152085.1 copper resistance system metallochaperone PcoE -
HYD35_RS26835 (HYD35_26825) 38600..38779 - 180 WP_024623170.1 type II toxin-antitoxin system RelE/ParE family toxin -
HYD35_RS26840 (HYD35_26830) 38840..40460 - 1621 Protein_36 ISL3 family transposase ISEc38 Transposase
HYD35_RS26845 (HYD35_26835) 40522..41031 + 510 WP_004196769.1 aquaporin -
HYD35_RS26850 (HYD35_26840) 41081..41578 - 498 WP_032436075.1 GNAT family N-acetyltransferase -
HYD35_RS26855 (HYD35_26845) 41910..42236 + 327 WP_004152092.1 metalloregulator ArsR/SmtB family transcription factor -
HYD35_RS26860 (HYD35_26850) 42233..42946 + 714 WP_004182006.1 arsenical resistance protein ArsH -
HYD35_RS26865 (HYD35_26855) 42955..43500 + 546 WP_004182005.1 sigma-70 family RNA polymerase sigma factor -
HYD35_RS26870 (HYD35_26860) 43576..43938 + 363 WP_004152095.1 arsenic metallochaperone ArsD family protein -
HYD35_RS26875 (HYD35_26865) 43963..45713 + 1751 Protein_43 arsenical pump-driving ATPase -
HYD35_RS26880 (HYD35_26870) 45835..46371 + 537 WP_004152096.1 GNAT family N-acetyltransferase -
HYD35_RS26885 (HYD35_26875) 46404..46829 - 426 WP_004152097.1 glutaredoxin-dependent arsenate reductase -
HYD35_RS26890 (HYD35_26880) 46842..48131 - 1290 WP_004152098.1 arsenite efflux transporter membrane subunit ArsB -
HYD35_RS26895 (HYD35_26885) 48179..49930 - 1752 WP_004152099.1 Arsenical pump-driving ATPase VF
HYD35_RS26900 (HYD35_26890) 49948..50310 - 363 WP_004152100.1 arsenite efflux transporter metallochaperone ArsD -
HYD35_RS26905 (HYD35_26895) 50360..50710 - 351 WP_004152101.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
HYD35_RS26910 (HYD35_26900) 51068..51337 + 270 WP_004152102.1 hypothetical protein -
HYD35_RS26915 (HYD35_26905) 51325..51900 + 576 WP_004152103.1 hypothetical protein -
HYD35_RS26920 (HYD35_26910) 51931..52425 + 495 WP_004152104.1 DNA-binding protein -
HYD35_RS26925 (HYD35_26915) 52469..52837 + 369 WP_004152105.1 hypothetical protein -
HYD35_RS26930 (HYD35_26920) 52871..53074 + 204 WP_004152106.1 HHA domain-containing protein -
HYD35_RS26935 (HYD35_26925) 53123..53380 + 258 WP_004152107.1 hypothetical protein -
HYD35_RS26940 (HYD35_26930) 53456..53710 + 255 WP_004152108.1 hypothetical protein -
HYD35_RS26945 (HYD35_26935) 53886..54152 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
HYD35_RS26950 (HYD35_26940) 54140..54622 + 483 WP_003026803.1 GNAT family N-acetyltransferase Toxin Detail
HYD35_RS26955 (HYD35_26945) 54781..55946 - 1166 Protein_59 IS3 family transposase ISKpn38 Transposase
HYD35_RS26960 (HYD35_26950) 56123..57085 - 963 WP_004152113.1 zinc metalloprotease HtpX -
HYD35_RS26965 (HYD35_26955) 57072..57560 - 489 WP_004152114.1 phosphate-starvation-inducible PsiE family protein -
HYD35_RS26970 (HYD35_26960) 58058..58255 - 198 WP_004152115.1 hypothetical protein -
HYD35_RS26975 (HYD35_26965) 58255..61050 - 2796 WP_004152116.1 ATP-dependent Clp protease ATP-binding subunit ClpC VF
HYD35_RS26980 (HYD35_26970) 61174..61743 - 570 WP_004152117.1 Spore protein SP21 VF
HYD35_RS26985 (HYD35_26975) 61778..62059 - 282 WP_004152118.1 helix-turn-helix domain-containing protein -
HYD35_RS26990 (HYD35_26980) 62303..62566 - 264 WP_004118208.1 hypothetical protein -
HYD35_RS26995 (HYD35_26985) 62581..62844 + 264 WP_004118209.1 transposase -
HYD35_RS27000 (HYD35_26990) 62789..62905 + 117 Protein_68 transposase domain-containing protein -
HYD35_RS27005 (HYD35_26995) 63090..63787 + 698 WP_223174644.1 IS1 family transposase -
HYD35_RS27010 (HYD35_27000) 63995..65002 - 1008 WP_004181997.1 formamidase -
HYD35_RS27015 (HYD35_27005) 65038..65727 - 690 WP_004181996.1 urea ABC transporter ATP-binding subunit UrtE -
HYD35_RS27020 (HYD35_27010) 65738..66487 - 750 WP_004181995.1 urea ABC transporter ATP-binding protein UrtD -
HYD35_RS27025 (HYD35_27015) 66484..67599 - 1116 WP_004181994.1 urea ABC transporter permease subunit UrtC -
HYD35_RS27030 (HYD35_27020) 67609..68535 - 927 WP_004181993.1 urea ABC transporter permease subunit UrtB -
HYD35_RS27035 (HYD35_27025) 68592..69764 - 1173 WP_223176254.1 urea ABC transporter substrate-binding protein -
HYD35_RS27040 (HYD35_27030) 70087..73467 + 3381 WP_004181991.1 Aerobic respiration control sensor protein ArcB VF
HYD35_RS28410 (HYD35_27035) 73487..74305 + 819 Protein_77 putative cyclic di-GMP phosphodiesterase VF
HYD35_RS28415 (HYD35_27040) 74312..74866 + 555 Protein_78 IS91 family transposase IS1294 Transposase
HYD35_RS27055 (HYD35_27045) 74910..75290 - 381 Protein_79 integrase core domain-containing protein -
HYD35_RS27060 (HYD35_27050) 75347..76315 - 969 WP_072143344.1 IS5 family transposase IS903B Transposase
HYD35_RS27065 (HYD35_27055) 76589..77593 + 1005 WP_000427614.1 IS110 family transposase IS5075 Transposase
HYD35_RS28350 78079..78393 - 315 Protein_82 NAD(P)-dependent oxidoreductase -
HYD35_RS27070 (HYD35_27065) 78498..79633 + 1136 WP_201282090.1 IS3 family transposase ISEc15 Transposase
HYD35_RS27075 (HYD35_27070) 80019..80339 + 321 WP_004197483.1 hypothetical protein -
HYD35_RS27080 (HYD35_27075) 80445..81476 - 1032 WP_032425611.1 IS630 family transposase ISEc33 Transposase
HYD35_RS27085 (HYD35_27080) 82802..83815 - 1014 WP_016831068.1 plasmid replication initiator RepA -
HYD35_RS28360 84000..84174 - 175 Protein_87 protein CopA/IncA -
HYD35_RS27095 (HYD35_27090) 84257..84526 - 270 WP_016831067.1 replication regulatory protein RepA -
HYD35_RS27100 (HYD35_27095) 84662..85213 - 552 WP_025983260.1 Phospholipase D VF
HYD35_RS27105 (HYD35_27100) 85317..85625 - 309 WP_016831065.1 hypothetical protein -
HYD35_RS27110 (HYD35_27105) 85622..86272 - 651 WP_016831064.1 DUF2726 domain-containing protein -
HYD35_RS27115 (HYD35_27110) 86328..86549 - 222 WP_016831063.1 hypothetical protein -
HYD35_RS27120 (HYD35_27115) 87019..87365 - 347 Protein_93 DUF6404 family protein -
HYD35_RS27125 (HYD35_27120) 87385..87981 - 597 WP_016831061.1 fertility inhibition protein FinO -
HYD35_RS27130 (HYD35_27125) 88053..88778 - 726 WP_016831060.1 type-F conjugative transfer system pilin acetylase TraX -
HYD35_RS27135 (HYD35_27130) 88859..94117 - 5259 WP_104446944.1 Multifunctional conjugation protein TraI Relaxase
HYD35_RS27140 (HYD35_27135) 94117..96399 - 2283 WP_016831058.1 type IV conjugative transfer system coupling protein TraD -
HYD35_RS27145 (HYD35_27140) 96526..97215 - 690 WP_072159541.1 hypothetical protein -
HYD35_RS27150 (HYD35_27145) 97408..98139 - 732 WP_016831056.1 conjugal transfer complement resistance protein TraT -
HYD35_RS27155 (HYD35_27150) 98390..98992 - 603 WP_071604857.1 hypothetical protein -
HYD35_RS27160 (HYD35_27155) 99015..101837 - 2823 WP_016831055.1 conjugal transfer mating-pair stabilization protein TraG -
HYD35_RS27165 (HYD35_27160) 101837..103216 - 1380 WP_072159542.1 conjugal transfer pilus assembly protein TraH -
HYD35_RS27170 (HYD35_27165) 103194..103637 - 444 WP_016831053.1 F-type conjugal transfer protein TrbF -
HYD35_RS27175 (HYD35_27170) 103683..104240 - 558 WP_004152678.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
HYD35_RS27180 (HYD35_27175) 104212..104451 - 240 WP_004144400.1 type-F conjugative transfer system pilin chaperone TraQ -
HYD35_RS27185 (HYD35_27180) 104462..105214 - 753 WP_004152677.1 type-F conjugative transfer system pilin assembly protein TraF -
HYD35_RS27190 (HYD35_27185) 105235..105561 - 327 WP_016831051.1 hypothetical protein -
HYD35_RS27195 (HYD35_27190) 105574..105822 - 249 WP_004152675.1 hypothetical protein -
HYD35_RS27200 (HYD35_27195) 105800..106054 - 255 WP_015065558.1 conjugal transfer protein TrbE -
HYD35_RS27205 (HYD35_27200) 106086..108041 - 1956 WP_023313940.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
HYD35_RS27210 (HYD35_27205) 108100..108747 - 648 WP_016831049.1 type-F conjugative transfer system pilin assembly protein TrbC -
HYD35_RS27215 (HYD35_27210) 108826..109002 - 177 WP_162866177.1 hypothetical protein -
HYD35_RS27220 (HYD35_27215) 109023..110012 - 990 WP_015632509.1 conjugal transfer pilus assembly protein TraU -
HYD35_RS27225 (HYD35_27220) 110009..110410 - 402 WP_016831047.1 hypothetical protein -
HYD35_RS27230 (HYD35_27225) 110445..111080 - 636 WP_016831046.1 type-F conjugative transfer system protein TraW -
HYD35_RS27235 (HYD35_27230) 111080..111469 - 390 WP_004167468.1 type-F conjugative transfer system protein TrbI -
HYD35_RS27240 (HYD35_27235) 111469..114108 - 2640 WP_016831045.1 type IV secretion system protein TraC -
HYD35_RS27245 (HYD35_27240) 114180..114578 - 399 WP_023158008.1 hypothetical protein -
HYD35_RS28365 114586..114804 - 219 WP_072196435.1 hypothetical protein -
HYD35_RS28370 114818..114976 - 159 WP_223178560.1 hypothetical protein -
HYD35_RS27255 (HYD35_27250) 115019..115423 - 405 WP_016831042.1 hypothetical protein -
HYD35_RS27260 (HYD35_27255) 115490..115801 - 312 WP_016831041.1 hypothetical protein -
HYD35_RS27265 (HYD35_27260) 115802..116020 - 219 WP_014386199.1 hypothetical protein -
HYD35_RS27270 (HYD35_27265) 116044..116333 - 290 Protein_124 hypothetical protein -
HYD35_RS27275 (HYD35_27270) 116338..116748 - 411 WP_032409654.1 hypothetical protein -
HYD35_RS27280 (HYD35_27275) 116880..117464 - 585 WP_210147437.1 type IV conjugative transfer system lipoprotein TraV -
HYD35_RS27285 (HYD35_27280) 117487..118083 - 597 Protein_127 conjugal transfer protein TraP -
HYD35_RS27290 (HYD35_27285) 118076..119500 - 1425 WP_016831036.1 F-type conjugal transfer pilus assembly protein TraB -
HYD35_RS27295 (HYD35_27290) 119500..120240 - 741 WP_014386193.1 type-F conjugative transfer system secretin TraK -
HYD35_RS27300 (HYD35_27295) 120227..120793 - 567 WP_016831035.1 type IV conjugative transfer system protein TraE -
HYD35_RS27305 (HYD35_27300) 120813..121118 - 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
HYD35_RS27310 (HYD35_27305) 121132..121500 - 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
HYD35_RS27315 (HYD35_27310) 121562..121768 - 207 WP_171773970.1 TraY domain-containing protein -
HYD35_RS27320 (HYD35_27315) 121901..122620 - 720 WP_016831034.1 conjugal transfer protein TrbJ -
HYD35_RS27325 (HYD35_27320) 122820..123236 - 417 WP_072145360.1 conjugal transfer relaxosome DNA-binding protein TraM -
HYD35_RS27330 (HYD35_27325) 123627..124112 + 486 WP_004178063.1 hypothetical protein VF
HYD35_RS27335 (HYD35_27330) 124145..124474 - 330 WP_011977736.1 DUF5983 family protein -
HYD35_RS27340 (HYD35_27335) 124507..125064 - 558 Protein_138 DUF945 domain-containing protein -
HYD35_RS27345 (HYD35_27340) 125213..126073 - 861 WP_000027057.1 Beta-lactamase TEM ARG
HYD35_RS27350 (HYD35_27345) 126256..126813 - 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
HYD35_RS27355 (HYD35_27350) 126977..129982 + 3006 WP_210147355.1 Tn3 family transposase TnpA_Tn3 Transposase
HYD35_RS27360 (HYD35_27355) 130005..130283 - 279 Protein_142 DUF945 domain-containing protein -
HYD35_RS27365 (HYD35_27360) 131116..131529 - 414 WP_004182074.1 helix-turn-helix domain-containing protein -
HYD35_RS27370 (HYD35_27365) 131530..131808 - 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
HYD35_RS27375 (HYD35_27370) 131798..132118 - 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
HYD35_RS27380 (HYD35_27375) 132199..132423 - 225 WP_004152719.1 hypothetical protein -
HYD35_RS27385 (HYD35_27380) 132434..132646 - 213 WP_004182070.1 hypothetical protein -
HYD35_RS27390 (HYD35_27385) 132707..133063 - 357 WP_004152717.1 hypothetical protein -
HYD35_RS27395 (HYD35_27390) 133699..134049 - 351 WP_004182068.1 hypothetical protein -
HYD35_RS27400 (HYD35_27395) 134046..134318 - 273 WP_004182067.1 hypothetical protein -
HYD35_RS27405 (HYD35_27400) 135014..135136 - 123 WP_085842394.1 Hok/Gef family protein -
HYD35_RS28375 135081..135233 - 153 Protein_152 FlmC family protein -
HYD35_RS27410 (HYD35_27405) 135403..135777 - 375 WP_004182064.1 hypothetical protein -
HYD35_RS27415 (HYD35_27410) 135833..136159 - 327 WP_004152639.1 hypothetical protein -
HYD35_RS27420 (HYD35_27415) 136156..136884 - 729 WP_004152640.1 plasmid SOS inhibition protein A -
HYD35_RS27425 (HYD35_27420) 136881..137312 - 432 WP_004182061.1 conjugation system SOS inhibitor PsiB -
HYD35_RS27430 (HYD35_27425) 137357..139414 - 2058 WP_004182059.1 ParB/RepB/Spo0J family partition protein -
HYD35_RS27435 (HYD35_27430) 139484..139732 - 249 WP_004182058.1 DUF905 domain-containing protein -
HYD35_RS27440 (HYD35_27435) 139781..140323 - 543 WP_004182056.1 single-stranded DNA-binding protein -
HYD35_RS27445 (HYD35_27440) 141158..141721 - 564 WP_004182054.1 methyltransferase -
HYD35_RS27450 (HYD35_27445) 141769..143124 - 1356 WP_004182052.1 DUF3560 domain-containing protein -
HYD35_RS27455 (HYD35_27450) 143176..143406 - 231 WP_001568051.1 hypothetical protein -
HYD35_RS27460 (HYD35_27455) 143498..143725 - 228 WP_004182050.1 hypothetical protein -
HYD35_RS27465 (HYD35_27460) 144452..144769 - 318 WP_004118473.1 hypothetical protein -
HYD35_RS27470 (HYD35_27465) 144804..145058 - 255 WP_004152754.1 DNA polymerase III subunit theta -
HYD35_RS27475 (HYD35_27470) 145295..145720 - 426 WP_004118478.1 antirestriction protein -
HYD35_RS27480 (HYD35_27475) 146240..146470 - 231 WP_004118481.1 hypothetical protein -
HYD35_RS27485 (HYD35_27480) 146704..148215 - 1512 WP_024623221.1 Group II intron-encoded protein LtrA VF
HYD35_RS27490 (HYD35_27485) 148617..149042 + 426 WP_004182047.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
HYD35_RS27495 (HYD35_27490) 149042..150314 + 1273 Protein_170 Y-family DNA polymerase -
HYD35_RS27500 (HYD35_27495) 150393..150644 + 252 WP_004182043.1 hypothetical protein -
HYD35_RS27505 (HYD35_27500) 150889..152841 - 1953 WP_000037308.1 DUF262 domain-containing protein -
HYD35_RS27510 (HYD35_27505) 152838..154118 - 1281 WP_004182042.1 DUF262 domain-containing protein -
HYD35_RS27515 (HYD35_27510) 155086..155781 + 696 Protein_174 IS1 family transposase IS1A Transposase
HYD35_RS27520 (HYD35_27515) 156559..157675 - 1117 Protein_175 IS3 family transposase ISSen4 Transposase
HYD35_RS27525 (HYD35_27520) 158718..159689 - 972 WP_004182039.1 ParB/RepB/Spo0J family plasmid partition protein -
HYD35_RS27530 (HYD35_27525) 159689..160855 - 1167 WP_004182032.1 Sporulation initiation inhibitor protein Soj VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance