MGE detailed information

MGE type: Integrative_Conjugative_Elements        MGE length: 168512 bp
Accession: NZ_CP055170        Location: 3125199..3293710         Organism: Shigella flexneri strain STEFF_22       Replicon: chromosome


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ49_RS14970 (3120281) 3120281..3121696 - 1416 WP_000695655.1 glutamate--tRNA ligase -
HUZ49_RS15000 (3122628) 3122628..3122969 + 342 WP_000201411.1 FlxA-like family protein -
HUZ49_RS15005 (3122960) 3122960..3123886 - 927 WP_001109794.1 LysR family transcriptional regulator -
HUZ49_RS15010 (3123976) 3123976..3124974 + 999 WP_000765604.1 bile acid:sodium symporter family protein -
HUZ49_RS15015 (3124971) 3124971..3125189 - 219 WP_000410201.1 DUF3820 family protein -
HUZ49_RS15020 (3125191) 3125191..3127206 - 2016 WP_000443665.1 NAD-dependent DNA ligase LigA -
HUZ49_RS15025 (3127277) 3127277..3128275 - 999 WP_001299866.1 cell division protein ZipA -
HUZ49_RS15030 (3128505) 3128505..3129266 + 762 WP_000254843.1 sulfate transporter CysZ -
HUZ49_RS15035 (3129451) 3129451..3130422 + 972 WP_000034402.1 cysteine synthase A -
HUZ49_RS15040 (3130806) 3130806..3131063 + 258 WP_000487600.1 phosphocarrier protein Hpr -
HUZ49_RS15045 (3131108) 3131108..3132835 + 1728 WP_000623136.1 phosphoenolpyruvate-protein phosphotransferase PtsI -
HUZ49_RS15050 (3132876) 3132876..3133385 + 510 WP_000522247.1 PTS glucose transporter subunit IIA -
HUZ49_RS15055 (3133427) 3133427..3134278 - 852 WP_000096660.1 pyridoxine/pyridoxal/pyridoxamine kinase -
HUZ49_RS15060 (3134383) 3134383..3134751 + 369 WP_000719943.1 YfeK family protein -
HUZ49_RS15065 (3134754) 3134754..3135665 - 912 WP_001297645.1 cysteine synthase B -
HUZ49_RS15070 (3135799) 3135799..3136896 - 1098 WP_000021040.1 Sulfate/thiosulfate import ATP-binding protein CysA VF
HUZ49_RS15075 (3136886) 3136886..3137761 - 876 WP_000852685.1 sulfate/thiosulfate ABC transporter permease CysW -
HUZ49_RS15080 (3137761) 3137761..3138594 - 834 WP_000458406.1 sulfate/thiosulfate ABC transporter permease CysT -
HUZ49_RS15085 (3138594) 3138594..3139610 - 1017 WP_000290230.1 thiosulfate/sulfate ABC transporter substrate-binding protein CysP -
HUZ49_RS15090 (3139781) 3139781..3140572 - 792 WP_000517431.1 Oxidoreductase UcpA VF
HUZ49_RS15095 (3140701) 3140701..3141558 - 858 WP_000966466.1 HTH-type transcriptional regulator MurR -
HUZ49_RS15100 (3141722) 3141722..3142618 + 897 WP_001175648.1 N-acetylmuramic acid 6-phosphate etherase -
HUZ49_RS15105 (3142622) 3142622..3144046 + 1425 WP_001040494.1 PTS N-acetylmuramic acid transporter subunit IIBC -
HUZ49_RS15110 (3144051) 3144051..3145355 + 1305 WP_001315775.1 Protein flp VF
HUZ49_RS15115 (3145413) 3145413..3146312 - 900 WP_001493264.1 porphyrinogen peroxidase -
HUZ49_RS15120 (3146408) 3146408..3146983 - 576 WP_000838945.1 RpoE-regulated lipoprotein -
HUZ49_RS15125 (3147044) 3147044..3147493 - 450 WP_000842944.1 DUF2919 domain-containing protein -
HUZ49_RS15130 (3147480) 3147480..3147905 - 426 WP_000406000.1 GNAT family acetyltransferase -
HUZ49_RS15135 (3148119) 3148119..3148988 + 870 WP_000102886.1 N-acetylmuramoyl-L-alanine amidase AmiA -
HUZ49_RS15140 (3148992) 3148992..3149891 + 900 WP_000801367.1 oxygen-dependent coproporphyrinogen oxidase -
HUZ49_RS15145 (3149897) 3149897..3150949 - 1053 WP_000753700.1 HTH-type transcriptional regulator EutR -
HUZ49_RS15150 (3150995) 3150995..3151495 - 501 WP_000606257.1 ethanolamine utilization microcompartment protein EutK -
HUZ49_RS15155 (3151508) 3151508..3152167 - 660 WP_001111038.1 ethanolamine utilization microcompartment protein EutL -
HUZ49_RS15160 (3152177) 3152177..3153064 - 888 WP_000372364.1 ethanolamine ammonia-lyase subunit beta -
HUZ49_RS15165 (3153085) 3153085..3154446 - 1362 WP_000769961.1 ethanolamine ammonia-lyase subunit alpha -
HUZ49_RS15170 (3154458) 3154458..3155861 - 1404 WP_001097477.1 ethanolamine ammonia-lyase reactivating factor EutA -
HUZ49_RS15175 (3155858) 3155858..3157084 - 1227 WP_000512372.1 ethanolamine utilization protein EutH -
HUZ49_RS15180 (3157201) 3157201..3158388 - 1188 WP_001330930.1 NAD-dependent methanol dehydrogenase VF
HUZ49_RS15185 (3158378) 3158378..3159214 - 837 WP_000929726.1 ethanolamine utilization protein EutJ -
HUZ49_RS15190 (3159225) 3159225..3160628 - 1404 WP_001075711.1 Aldehyde-alcohol dehydrogenase VF
HUZ49_RS15195 (3160640) 3160640..3160927 - 288 WP_000762196.1 ethanolamine utilization microcompartment protein EutN -
HUZ49_RS15200 (3161034) 3161034..3161327 - 294 WP_000387713.1 ethanolamine utilization microcompartment protein EutM -
HUZ49_RS15205 (3161366) 3161366..3162382 - 1017 WP_000582978.1 phosphate acetyltransferase -
HUZ49_RS15210 (3162379) 3162379..3163182 - 804 WP_000651298.1 ethanolamine utilization cob(I)yrinic acid a,c-diamide adenosyltransferase EutT -
HUZ49_RS15215 (3163179) 3163179..3163880 - 702 WP_000733903.1 ethanolamine utilization acetate kinase EutQ -
HUZ49_RS15220 (3163855) 3163855..3164334 - 480 WP_000820764.1 ethanolamine utilization acetate kinase EutP -
HUZ49_RS15225 (3164347) 3164347..3164682 - 336 WP_000356956.1 ethanolamine utilization microcompartment protein EutS -
HUZ49_RS15230 (3164975) 3164975..3167254 - 2280 WP_000342642.1 NADP-dependent oxaloacetate-decarboxylating malate dehydrogenase -
HUZ49_RS15235 (3167543) 3167543..3168493 + 951 WP_001003709.1 transaldolase -
HUZ49_RS15240 (3168513) 3168513..3170516 + 2004 WP_000087298.1 transketolase -
HUZ49_RS15245 (3170593) 3170593..3171636 - 1044 WP_001270527.1 DUF1176 domain-containing protein -
HUZ49_RS15250 (3171762) 3171762..3172337 - 576 WP_000193711.1 GDP-mannose pyrophosphatase NudK -
HUZ49_RS15255 (3172405) 3172405..3174384 - 1980 WP_001078875.1 formate-dependent uric acid utilization protein AegA -
HUZ49_RS15260 (3174590) 3174590..3176290 + 1701 WP_000636129.1 nitrate/nitrite two-component system sensor histidine kinase NarQ -
HUZ49_RS15265 (3176454) 3176454..3179567 + 3114 WP_063108204.1 Multidrug efflux pump subunit AcrB VF
HUZ49_RS15270 (3179666) 3179666..3179725 - 60 WP_001386977.1 protein YpfM -
HUZ49_RS15275 (3180106) 3180106..3180462 + 357 WP_000258247.1 ArsC family reductase -
HUZ49_RS15280 (3180466) 3180466..3181593 + 1128 WP_001277809.1 succinyl-diaminopimelate desuccinylase -
HUZ49_RS15285 (3181621) 3181621..3181821 + 201 WP_000383836.1 YpfN family protein -
HUZ49_RS15290 (3181931) 3181931..3182629 - 699 WP_000679812.1 esterase -
HUZ49_RS15295 (3182703) 3182703..3184718 - 2016 WP_001543081.1 tRNA cytosine(34) acetyltransferase TmcA -
HUZ49_RS15300 (3184733) 3184733..3185596 - 864 WP_001267507.1 neutral zinc metallopeptidase -
HUZ49_RS15305 (3185743) 3185743..3186141 - 399 WP_000911331.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
HUZ49_RS15310 (3186141) 3186141..3186368 - 228 WP_000450524.1 toxin-antitoxin system antitoxin VapB Antitoxin Detail
HUZ49_RS15315 (3186522) 3186522..3187235 - 714 WP_001295467.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
HUZ49_RS15320 (3187448) 3187448..3188482 - 1035 WP_001297320.1 outer membrane protein assembly factor BamC -
HUZ49_RS15325 (3188499) 3188499..3189377 - 879 WP_001295469.1 4-hydroxy-tetrahydrodipicolinate synthase -
HUZ49_RS15330 (3189523) 3189523..3190095 + 573 WP_000176187.1 glycine cleavage system transcriptional repressor -
HUZ49_RS15335 (3190095) 3190095..3190565 + 471 WP_001068682.1 thioredoxin-dependent thiol peroxidase -
HUZ49_RS15340 (3190818) 3190818..3191435 + 618 WP_001352202.1 hydrogenase 4 subunit HyfA -
HUZ49_RS15345 (3191684) 3191684..3193452 + 1769 Protein_3007 hydrogenase 4 subunit B -
HUZ49_RS15350 (3193463) 3193463..3194410 + 948 WP_001358398.1 hydrogenase 4 subunit HyfC -
HUZ49_RS15355 (3194427) 3194427..3195864 + 1438 Protein_3009 hydrogenase 4 subunit HyfD -
HUZ49_RS15360 (3195876) 3195876..3196526 + 651 WP_000147987.1 hydrogenase 4 membrane subunit -
HUZ49_RS15365 (3196531) 3196531..3198117 + 1587 Protein_3011 hydrogenase 4 subunit F -
HUZ49_RS15370 (3198107) 3198107..3199774 + 1668 WP_001102282.1 hydrogenase 4 catalytic subunit HyfG -
HUZ49_RS15375 (3199784) 3199784..3200329 + 546 WP_000916058.1 hydrogenase 4 subunit H -
HUZ49_RS15380 (3200326) 3200326..3201083 + 758 Protein_3014 hydrogenase 4 catalytic subunit HyfI -
HUZ49_RS15385 (3201076) 3201076..3201489 + 414 WP_001307332.1 hydrogenase 4 assembly chaperone HyfJ -
HUZ49_RS15390 (3201519) 3201519..3203531 + 2013 WP_001251577.1 DNA-binding transcriptional activator HyfR VF
HUZ49_RS15395 (3203553) 3203553..3204400 + 848 Protein_3017 formate transporter FocB -
HUZ49_RS15400 (3204438) 3204438..3205499 - 1062 WP_000892044.1 AI-2E family transporter -
HUZ49_RS15405 (3205712) 3205712..3207175 + 1464 WP_000489667.1 beta-barrel assembly-enhancing protease -
HUZ49_RS15410 (3207196) 3207196..3207555 + 360 WP_000166449.1 arsenate reductase (glutaredoxin) -
HUZ49_RS15415 (3207693) 3207693..3208394 - 702 WP_001307333.1 DnaA inactivator Hda -
HUZ49_RS15420 (3208489) 3208489..3209778 - 1290 WP_000198328.1 uracil permease -
HUZ49_RS15425 (3209864) 3209864..3210490 - 627 WP_001295473.1 uracil phosphoribosyltransferase -
HUZ49_RS15430 (3210815) 3210815..3211852 + 1038 WP_001295474.1 Phosphoribosylformylglycinamidine cyclo-ligase VF
HUZ49_RS15435 (3211852) 3211852..3212490 + 639 WP_001028614.1 phosphoribosylglycinamide formyltransferase -
HUZ49_RS15440 (3212661) 3212661..3214727 + 2067 WP_000529576.1 polyphosphate kinase 1 -
HUZ49_RS15445 (3214732) 3214732..3216273 + 1542 WP_001121363.1 exopolyphosphatase -
HUZ49_RS15450 (3216312) 3216312..3218555 - 2244 WP_000772774.1 Cyclic di-GMP phosphodiesterase PdeF VF
HUZ49_RS15455 (3218737) 3218737..3218889 - 153 WP_000017552.1 hypothetical protein -
HUZ49_RS15460 (3218907) 3218907..3219098 + 192 WP_000076001.1 YfgG family protein -
HUZ49_RS15465 (3219409) 3219409..3219927 + 519 WP_001295476.1 glycine zipper 2TM domain-containing protein -
HUZ49_RS15470 (3219943) 3219943..3220482 + 540 WP_000755179.1 DUF5384 family protein -
HUZ49_RS15475 (3220933) 3220933..3222111 - 1179 WP_063119554.1 GIY-YIG nuclease family protein -
HUZ49_RS15480 (3222104) 3222104..3224149 - 2046 WP_063119553.1 DEAD/DEAH box helicase -
HUZ49_RS15485 (3224146) 3224146..3226920 - 2775 WP_063119552.1 class I SAM-dependent DNA methyltransferase -
HUZ49_RS15490 (3227218) 3227218..3227637 - 420 WP_063119551.1 HigA family addiction module antitoxin -
HUZ49_RS15495 (3227719) 3227719..3229110 - 1392 WP_063119555.1 P-type conjugative transfer protein TrbL -
HUZ49_RS15500 (3229298) 3229298..3230092 - 795 WP_063119550.1 P-type conjugative transfer protein TrbJ -
HUZ49_RS15505 (3230174) 3230174..3230527 - 354 WP_063108210.1 conjugal transfer transcriptional regulator TraJ -
HUZ49_RS15510 (3231214) 3231214..3231975 - 762 WP_063108211.1 hypothetical protein -
HUZ49_RS15515 (3231962) 3231962..3232819 - 858 WP_063108212.1 helicase RepA family protein -
HUZ49_RS15520 (3232825) 3232825..3233055 - 231 WP_001193557.1 AlpA family phage regulatory protein -
HUZ49_RS15525 (3233142) 3233142..3234104 + 963 WP_227504456.1 LuxR family transcriptional regulator -
HUZ49_RS15530 (3234682) 3234682..3235311 - 630 WP_063108213.1 hypothetical protein -
HUZ49_RS15535 (3235435) 3235435..3236625 - 1191 WP_063108214.1 Prophage integrase IntA ; Integrase Integrase
HUZ49_RS15540 (3236933) 3236933..3238510 - 1578 WP_000138282.1 glutamine-hydrolyzing GMP synthase -
HUZ49_RS15545 (3238579) 3238579..3240045 - 1467 WP_001299507.1 IMP dehydrogenase -
HUZ49_RS15550 (3240207) 3240207..3241577 + 1371 WP_000937892.1 exodeoxyribonuclease VII large subunit -
HUZ49_RS15555 (3241574) 3241574..3241789 - 216 WP_001295478.1 zinc ribbon domain-containing protein -
HUZ49_RS15560 (3241859) 3241859..3243331 - 1473 WP_000249410.1 ribosome biogenesis GTPase Der -
HUZ49_RS15565 (3243448) 3243448..3244626 - 1179 WP_001177048.1 outer membrane protein assembly factor BamB -
HUZ49_RS15570 (3244637) 3244637..3245257 - 621 WP_000409205.1 ancillary SecYEG translocon subunit YfgM -
HUZ49_RS15575 (3245275) 3245275..3246549 - 1275 WP_001107167.1 histidine--tRNA ligase -
HUZ49_RS15580 (3246660) 3246660..3247778 - 1119 WP_000551807.1 flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase -
HUZ49_RS15585 (3247805) 3247805..3248818 - 1014 WP_001090844.1 cytoskeleton protein RodZ -
HUZ49_RS15590 (3249103) 3249103..3250257 - 1155 WP_000003317.1 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN -
HUZ49_RS15595 (3250407) 3250407..3250838 - 432 WP_000963837.1 nucleoside-diphosphate kinase -
HUZ49_RS15600 (3250987) 3250987..3253299 - 2313 WP_039022555.1 peptidoglycan glycosyltransferase PbpC -
HUZ49_RS15605 (3253300) 3253300..3258261 - 4962 WP_000736307.1 alpha2-macroglobulin -
HUZ49_RS15610 (3258468) 3258468..3259313 + 846 WP_000108626.1 3-mercaptopyruvate sulfurtransferase -
HUZ49_RS24025 (3259649) 3259649..3259774 + 126 WP_001385884.1 small toxic inner membrane protein TimP -
HUZ49_RS15615 (3259806) 3259806..3260582 - 777 WP_001299505.1 enhanced serine sensitivity protein SseB -
HUZ49_RS15620 (3260724) 3260724..3262007 - 1284 WP_000133582.1 aminopeptidase PepB -
HUZ49_RS15625 (3262185) 3262185..3262385 - 201 WP_000523616.1 Fe-S cluster assembly protein IscX -
HUZ49_RS15630 (3262397) 3262397..3262732 - 336 WP_001124469.1 ISC system 2Fe-2S type ferredoxin -
HUZ49_RS15635 (3262734) 3262734..3264584 - 1851 WP_001196613.1 Fe-S protein assembly chaperone HscA -
HUZ49_RS15640 (3264601) 3264601..3265116 - 516 WP_000384411.1 co-chaperone HscB -
HUZ49_RS15645 (3265212) 3265212..3265535 - 324 WP_000028953.1 iron-sulfur cluster assembly protein IscA -
HUZ49_RS15650 (3265552) 3265552..3265938 - 387 WP_000331707.1 Fe-S cluster assembly scaffold IscU -
HUZ49_RS15655 (3265966) 3265966..3267180 - 1215 WP_001295373.1 cysteine desulfurase -
HUZ49_RS15660 (3267292) 3267292..3267780 - 489 WP_001241357.1 Fe-S cluster assembly transcriptional regulator IscR -
HUZ49_RS15665 (3268050) 3268050..3268790 - 741 WP_000940019.1 tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ -
HUZ49_RS15670 (3268909) 3268909..3269712 + 804 WP_000553451.1 inositol-1-monophosphatase -
HUZ49_RS15675 (3269857) 3269857..3270711 + 855 WP_001299515.1 alpha/beta hydrolase -
HUZ49_RS15680 (3270902) 3270902..3272182 + 1281 WP_000983008.1 stationary phase inducible protein CsiE -
HUZ49_RS15685 (3272174) 3272174..3273313 - 1140 WP_000244193.1 3-phenylpropionate MFS transporter -
HUZ49_RS15690 (3273473) 3273473..3274363 - 891 WP_000423256.1 DNA-binding transcriptional regulator HcaR -
HUZ49_RS15695 (3274499) 3274499..3275860 + 1362 WP_063108215.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
HUZ49_RS15700 (3275857) 3275857..3276375 + 519 WP_001276072.1 3-phenylpropionate/cinnamic acid dioxygenase subunit beta -
HUZ49_RS15705 (3276375) 3276375..3276695 + 321 WP_001080102.1 bifunctional 3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit -
HUZ49_RS15710 (3276692) 3276692..3277504 + 813 WP_001281377.1 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase -
HUZ49_RS15715 (3277514) 3277514..3278716 + 1203 WP_000660797.1 phenylpropionate dioxygenase ferredoxin reductase subunit -
HUZ49_RS15720 (3278813) 3278813..3279235 + 423 WP_001094726.1 DoxX family protein -
HUZ49_RS15725 (3279283) 3279283..3280155 - 873 WP_000158547.1 aldose 1-epimerase -
HUZ49_RS15730 (3280167) 3280167..3281261 - 1095 WP_000700816.1 zinc-binding dehydrogenase -
HUZ49_RS15735 (3281294) 3281294..3282292 - 999 WP_001276691.1 ABC transporter permease -
HUZ49_RS15740 (3282317) 3282317..3283828 - 1512 WP_000493471.1 sugar ABC transporter ATP-binding protein -
HUZ49_RS15745 (3283851) 3283851..3284834 - 984 WP_001124918.1 substrate-binding domain-containing protein -
HUZ49_RS15750 (3284931) 3284931..3288212 - 3282 WP_053264724.1 DUF5107 domain-containing protein -
HUZ49_RS15755 (3288330) 3288330..3289523 + 1194 WP_001299519.1 ROK family protein -
HUZ49_RS15760 (3289587) 3289587..3290840 - 1254 WP_000919159.1 serine hydroxymethyltransferase -
HUZ49_RS15765 (3291168) 3291168..3292358 + 1191 WP_000883122.1 NO-inducible flavohemoprotein -
HUZ49_RS15770 (3292403) 3292403..3292741 - 339 WP_000717694.1 nitrogen regulatory protein P-II -
HUZ49_RS15775 (3292802) 3292802..3294136 - 1335 WP_001298983.1 two-component system response regulator GlrR -
HUZ49_RS15780 (3294126) 3294126..3294839 - 714 WP_001215888.1 two-component system QseEF-associated lipoprotein QseG -
HUZ49_RS15785 (3295004) 3295004..3296431 - 1428 WP_001297612.1 two component system sensor histidine kinase QseE/GlrK -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance