MGE detailed information
MGE type: Mobilizable plasmid MGE length: 133772 bp
Accession: NZ_CP054770 Location: 1..133772 Organism: Klebsiella pneumoniae strain KP20194b Replicon: plasmid pKP20194b-p2
Accession: NZ_CP054770 Location: 1..133772 Organism: Klebsiella pneumoniae strain KP20194b Replicon: plasmid pKP20194b-p2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HUS00_RS27930 () | 1797..2450 | + | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| HUS00_RS27935 () | 2543..2800 | + | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| HUS00_RS27940 () | 2733..3134 | + | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| HUS00_RS27945 () | 3383..3798 | + | 416 | Protein_4 | IS1 family transposase | - |
| HUS00_RS27950 () | 3834..4379 | - | 546 | Protein_5 | Tn3 family transposase TnpA_Tn3 | Transposase |
| HUS00_RS27955 () | 4445..5149 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUS00_RS27960 () | 5219..5410 | + | 192 | Protein_7 | transposase | - |
| HUS00_RS27965 () | 5660..6535 | + | 876 | WP_013188475.1 | Beta-lactamase Toho-1 | ARG |
| HUS00_RS27970 () | 6570..7538 | + | 969 | WP_013362812.1 | IS5 family transposase IS903B | Transposase |
| HUS00_RS27975 () | 7595..8692 | + | 1098 | Protein_10 | TonB-dependent receptor | - |
| HUS00_RS27980 () | 8760..9209 | - | 450 | Protein_11 | PAS domain-containing protein | - |
| HUS00_RS27985 () | 9289..9993 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUS00_RS27990 () | 10058..10648 | + | 591 | Protein_13 | IS91 family transposase ISSbo1 | Transposase |
| HUS00_RS27995 () | 11104..11808 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUS00_RS28000 () | 11859..12476 | - | 618 | Protein_15 | IS91 family transposase ISSbo1 | Transposase |
| HUS00_RS28005 () | 12486..12674 | - | 189 | WP_000957857.1 | hypothetical protein | - |
| HUS00_RS28010 () | 12766..13302 | + | 537 | WP_064441864.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HUS00_RS28015 () | 13485..14345 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| HUS00_RS28020 () | 14515..15270 | + | 756 | WP_012372818.1 | 16S rRNA (guanine(1405)-N(7))-methyltransferase | ARG |
| HUS00_RS28025 () | 15351..15632 | - | 282 | WP_015059004.1 | sodium/hydrogen exchanger | - |
| HUS00_RS28030 () | 15720..16424 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| HUS00_RS28035 () | 16490..16555 | + | 66 | Protein_22 | IS1 family transposase | - |
| HUS00_RS28040 () | 18004..18238 | + | 235 | Protein_23 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HUS00_RS28045 () | 18366..18647 | + | 282 | WP_001333089.1 | hypothetical protein | - |
| HUS00_RS28050 () | 18770..19120 | - | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| HUS00_RS28055 () | 19123..20085 | - | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| HUS00_RS28060 () | 20232..20525 | + | 294 | WP_032146011.1 | hypothetical protein | - |
| HUS00_RS28065 () | 20602..21285 | + | 684 | WP_000085883.1 | DNA methylase | - |
| HUS00_RS28070 () | 21286..21507 | + | 222 | WP_001104881.1 | hypothetical protein | - |
| HUS00_RS28075 () | 21521..21955 | + | 435 | WP_000274503.1 | DUF1380 family protein | - |
| HUS00_RS28080 () | 22006..22782 | + | 777 | WP_001383963.1 | hypothetical protein | - |
| HUS00_RS28085 () | 23200..23625 | + | 426 | WP_001198928.1 | antirestriction protein | - |
| HUS00_RS28090 () | 23672..24094 | + | 423 | WP_000271762.1 | DUF1380 family protein | - |
| HUS00_RS28095 () | 24091..24282 | + | 192 | WP_001027493.1 | hypothetical protein | - |
| HUS00_RS28100 () | 24596..26263 | - | 1668 | WP_012372796.1 | group II intron reverse transcriptase/maturase | - |
| HUS00_RS28105 () | 27663..27893 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| HUS00_RS28110 () | 27945..29306 | + | 1362 | WP_000170695.1 | DUF3560 domain-containing protein | - |
| HUS00_RS28115 () | 29353..29916 | + | 564 | WP_015059007.1 | class I SAM-dependent methyltransferase | - |
| HUS00_RS28120 () | 30002..30457 | - | 456 | Protein_39 | hypothetical protein | - |
| HUS00_RS28125 () | 30759..31286 | + | 528 | WP_000290834.1 | single-stranded DNA-binding protein | - |
| HUS00_RS28130 () | 31344..31577 | + | 234 | WP_000006003.1 | DUF905 family protein | - |
| HUS00_RS28135 () | 31638..33661 | + | 2024 | Protein_42 | ParB/RepB/Spo0J family partition protein | - |
| HUS00_RS28140 () | 33730..34164 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| HUS00_RS28145 () | 34161..34880 | + | 720 | WP_001276217.1 | plasmid SOS inhibition protein A | - |
| - () | 34892..35116 | + | 225 | NuclAT_0 | - | - |
| - () | 34892..35116 | + | 225 | NuclAT_0 | - | - |
| - () | 34892..35116 | + | 225 | NuclAT_0 | - | - |
| - () | 34892..35116 | + | 225 | NuclAT_0 | - | - |
| HUS00_RS28150 () | 35160..35318 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HUS00_RS28155 () | 35556..35933 | - | 378 | Protein_46 | hypothetical protein | - |
| HUS00_RS28160 () | 36233..36529 | + | 297 | WP_001272251.1 | hypothetical protein | - |
| HUS00_RS28165 () | 36640..37461 | + | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| HUS00_RS28170 () | 37758..38405 | - | 648 | WP_015059008.1 | hypothetical protein | VF |
| HUS00_RS28175 () | 38682..39065 | + | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| HUS00_RS28180 () | 39346..40050 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUS00_RS28185 () | 40104..40427 | - | 324 | Protein_52 | class II aldolase/adducin family protein | - |
| HUS00_RS28190 () | 40420..41672 | - | 1253 | Protein_53 | four-carbon acid sugar kinase family protein | - |
| HUS00_RS28195 () | 41684..42586 | - | 903 | WP_002903955.1 | NAD(P)-dependent oxidoreductase | - |
| HUS00_RS28200 () | 42848..43609 | + | 762 | WP_002210513.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| HUS00_RS28205 () | 43630..44490 | - | 861 | WP_002904004.1 | Beta-lactamase SHV-2 | ARG |
| HUS00_RS28210 () | 44627..44695 | + | 69 | Protein_57 | IS6 family transposase | - |
| HUS00_RS28215 () | 44731..47697 | - | 2967 | WP_001138014.1 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| HUS00_RS28220 () | 47701..48261 | - | 561 | WP_001161490.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| HUS00_RS28225 () | 48653..49270 | + | 618 | Protein_60 | replication protein | - |
| HUS00_RS28230 () | 49804..50082 | + | 279 | WP_013213990.1 | hypothetical protein | - |
| HUS00_RS28235 () | 50193..50618 | + | 426 | WP_013213989.1 | antirestriction protein | - |
| HUS00_RS28240 () | 50746..50901 | + | 156 | WP_013213988.1 | hypothetical protein | - |
| HUS00_RS28245 () | 50947..51243 | + | 297 | WP_013213987.1 | transcriptional regulator | - |
| HUS00_RS28250 () | 51248..51373 | + | 126 | Protein_65 | IS1182 family transposase ISKpn6 | Transposase |
| HUS00_RS28255 () | 51347..52228 | + | 882 | Protein_66 | IS1182 family transposase ISKpn6 | Transposase |
| HUS00_RS28260 () | 52478..53359 | - | 882 | WP_004199234.1 | Carbapenem-hydrolyzing beta-lactamase KPC | ARG |
| HUS00_RS28265 () | 53635..54615 | - | 981 | WP_013213985.1 | IS481 family transposase ISKpn27 | Transposase |
| HUS00_RS28270 () | 54738..55211 | - | 474 | WP_014343468.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| HUS00_RS28275 () | 55251..55955 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUS00_RS28280 () | 56020..57192 | - | 1173 | Protein_71 | transposase | - |
| HUS00_RS28285 () | 57267..57935 | - | 669 | WP_001300294.1 | putative signaling protein | VF |
| HUS00_RS28290 () | 57971..58207 | - | 237 | WP_000993386.1 | broad-spectrum mercury transporter MerE | - |
| HUS00_RS28295 () | 58204..58566 | - | 363 | WP_001277456.1 | mercury resistance co-regulator MerD | - |
| HUS00_RS28300 () | 58584..60278 | - | 1695 | WP_000105636.1 | mercury(II) reductase | - |
| HUS00_RS28305 () | 60330..60752 | - | 423 | WP_001340589.1 | organomercurial transporter MerC | - |
| HUS00_RS28310 () | 60788..61063 | - | 276 | WP_000732292.1 | mercury resistance system periplasmic binding protein MerP | - |
| HUS00_RS28315 () | 61077..61427 | - | 351 | WP_001294663.1 | mercuric transport protein MerT | - |
| HUS00_RS28320 () | 61499..61933 | + | 435 | WP_000429836.1 | IS607 family transposase ISChh1 | Transposase |
| HUS00_RS28325 () | 62012..63016 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| HUS00_RS28330 () | 63544..64944 | - | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| HUS00_RS28335 () | 64941..65621 | - | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| HUS00_RS28340 () | 65676..66605 | - | 930 | WP_004213583.1 | copper resistance inner membrane protein PcoD | - |
| HUS00_RS28345 () | 66610..66990 | - | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| HUS00_RS28350 () | 67030..67920 | - | 891 | WP_029884201.1 | copper resistance outer membrane transporter PcoB | - |
| HUS00_RS28355 () | 67926..69743 | - | 1818 | WP_004213580.1 | multicopper oxidase PcoA | - |
| HUS00_RS28360 () | 69977..70444 | + | 468 | WP_048336866.1 | hypothetical protein | - |
| HUS00_RS28365 () | 70711..71448 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| HUS00_RS28370 () | 71482..71679 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| HUS00_RS28375 () | 71720..74167 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| HUS00_RS28380 () | 74294..74734 | - | 441 | WP_000758228.1 | hypothetical protein | - |
| HUS00_RS28385 () | 74821..77967 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| HUS00_RS28390 () | 77978..79270 | - | 1293 | WP_004213579.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| HUS00_RS28395 () | 79384..79746 | - | 363 | WP_004213578.1 | cation efflux system protein CusF | - |
| HUS00_RS28400 () | 79775..81160 | - | 1386 | WP_004213577.1 | Cation efflux system protein CusC | VF |
| HUS00_RS28405 () | 81350..82030 | + | 681 | WP_004213574.1 | Transcriptional regulatory protein CusR | VF |
| HUS00_RS28410 () | 82023..83498 | + | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| HUS00_RS28415 () | 83749..84180 | + | 432 | WP_023302802.1 | silver-binding protein SilE | - |
| HUS00_RS28420 () | 84324..84674 | + | 351 | WP_004213569.1 | DUF305 domain-containing protein | - |
| HUS00_RS28425 () | 85061..85969 | - | 909 | WP_023302803.1 | HNH endonuclease | - |
| HUS00_RS28430 () | 86606..87580 | + | 975 | WP_004213565.1 | sensor domain-containing diguanylate cyclase | - |
| HUS00_RS28435 () | 88165..89109 | + | 945 | WP_011977810.1 | hypothetical protein | - |
| HUS00_RS28440 () | 89146..89538 | + | 393 | WP_011977811.1 | hypothetical protein | - |
| HUS00_RS28445 () | 89596..90117 | + | 522 | WP_013214008.1 | hypothetical protein | - |
| HUS00_RS28450 () | 90163..90366 | + | 204 | WP_011977813.1 | hypothetical protein | - |
| HUS00_RS28455 () | 90396..91400 | + | 1005 | WP_011977814.1 | hypothetical protein | - |
| HUS00_RS28460 () | 91584..92363 | + | 780 | WP_013214009.1 | site-specific integrase | - |
| HUS00_RS28465 () | 92409..92666 | - | 258 | WP_013214010.1 | hypothetical protein | - |
| HUS00_RS28470 () | 92795..92908 | - | 114 | WP_014343462.1 | hypothetical protein | - |
| HUS00_RS28475 () | 93444..94310 | + | 867 | WP_004118283.1 | replication initiation protein | - |
| HUS00_RS28480 () | 95420..96625 | + | 1206 | WP_011977818.1 | AAA family ATPase | - |
| HUS00_RS28485 () | 96625..97599 | + | 975 | WP_011977819.1 | ParB/RepB/Spo0J family partition protein | - |
| HUS00_RS28490 () | 97681..98952 | - | 1272 | WP_013214011.1 | Y-family DNA polymerase | - |
| HUS00_RS28495 () | 98952..99383 | - | 432 | WP_001568036.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| HUS00_RS28500 () | 99790..101277 | + | 1488 | WP_004178082.1 | group II intron reverse transcriptase/maturase | - |
| HUS00_RS28505 () | 101526..102497 | + | 972 | WP_004152353.1 | mediator of plasmid stability | - |
| HUS00_RS28510 () | 102500..103171 | + | 672 | WP_013214012.1 | plasmid partitioning/stability family protein | - |
| HUS00_RS28515 () | 103234..103464 | + | 231 | WP_001568040.1 | hypothetical protein | - |
| HUS00_RS28520 () | 103901..104602 | + | 702 | WP_001568041.1 | DNA methylase | - |
| HUS00_RS28525 () | 104602..104823 | + | 222 | WP_001568042.1 | hypothetical protein | - |
| HUS00_RS28530 () | 104833..105252 | + | 420 | WP_001568043.1 | DUF1380 domain-containing protein | - |
| HUS00_RS28535 () | 105306..106073 | + | 768 | WP_013214013.1 | hypothetical protein | - |
| HUS00_RS28540 () | 106754..107182 | + | 429 | WP_001568045.1 | antirestriction protein | - |
| HUS00_RS28545 () | 107225..107731 | + | 507 | WP_013214014.1 | antirestriction protein ArdA | - |
| HUS00_RS28550 () | 107774..107965 | + | 192 | WP_001568047.1 | hypothetical protein | - |
| HUS00_RS28555 () | 108153..108407 | + | 255 | WP_011977779.1 | DNA polymerase III subunit theta | - |
| HUS00_RS28560 () | 108442..108762 | + | 321 | WP_001568049.1 | hypothetical protein | - |
| HUS00_RS28565 () | 109442..109669 | + | 228 | WP_001568050.1 | hypothetical protein | - |
| HUS00_RS28570 () | 109761..109991 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| HUS00_RS28575 () | 110043..111398 | + | 1356 | WP_014343515.1 | DUF3560 domain-containing protein | - |
| HUS00_RS28580 () | 111446..112009 | + | 564 | WP_014343514.1 | methyltransferase | - |
| HUS00_RS28585 () | 112842..113384 | + | 543 | WP_014343512.1 | single-stranded DNA-binding protein | - |
| HUS00_RS28590 () | 113433..113681 | + | 249 | WP_001568055.1 | DUF905 domain-containing protein | - |
| HUS00_RS28595 () | 113751..115808 | + | 2058 | WP_015493064.1 | ParB/RepB/Spo0J family partition protein | - |
| HUS00_RS28600 () | 115853..116284 | + | 432 | WP_001568057.1 | conjugation system SOS inhibitor PsiB | - |
| HUS00_RS28605 () | 116281..117009 | + | 729 | WP_001568058.1 | plasmid SOS inhibition protein A | - |
| HUS00_RS28610 () | 117006..117332 | + | 327 | WP_013023807.1 | hypothetical protein | - |
| HUS00_RS28615 () | 117388..117762 | + | 375 | WP_014343510.1 | hypothetical protein | - |
| HUS00_RS28620 () | 117990..118148 | + | 159 | WP_014343509.1 | type I toxin-antitoxin system Hok family toxin | - |
| HUS00_RS28625 () | 118841..119113 | + | 273 | WP_040245921.1 | hypothetical protein | - |
| HUS00_RS28630 () | 119110..119460 | + | 351 | WP_040245917.1 | hypothetical protein | - |
| HUS00_RS28635 () | 119475..119792 | + | 318 | WP_014343505.1 | hypothetical protein | - |
| HUS00_RS28640 () | 120633..120989 | + | 357 | WP_014343501.1 | hypothetical protein | - |
| HUS00_RS28645 () | 121050..121262 | + | 213 | WP_014343500.1 | hypothetical protein | - |
| HUS00_RS28650 () | 121273..121497 | + | 225 | WP_014343499.1 | hypothetical protein | - |
| HUS00_RS28655 () | 121578..121898 | + | 321 | WP_014343498.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HUS00_RS28660 () | 121888..122166 | + | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| HUS00_RS28665 () | 123103..123924 | + | 822 | WP_004152492.1 | DUF945 domain-containing protein | - |
| HUS00_RS28670 () | 123957..124286 | + | 330 | WP_013214015.1 | hypothetical protein | - |
| HUS00_RS28675 () | 124319..124804 | - | 486 | WP_014343495.1 | hypothetical protein | VF |
| HUS00_RS28680 () | 125195..125611 | + | 417 | WP_014343494.1 | relaxosome protein TraM | - |
| HUS00_RS28685 () | 125811..126548 | + | 738 | WP_154244330.1 | conjugal transfer protein TrbJ | - |
| HUS00_RS28690 () | 126663..126869 | + | 207 | WP_171773970.1 | TraY domain-containing protein | - |
| HUS00_RS28695 () | 126931..127299 | + | 369 | WP_004194426.1 | type IV conjugative transfer system pilin TraA | - |
| HUS00_RS28700 () | 127313..127618 | + | 306 | WP_004144424.1 | type IV conjugative transfer system protein TraL | - |
| HUS00_RS28705 () | 127638..128003 | + | 366 | Protein_156 | type IV conjugative transfer system protein TraE | - |
| HUS00_RS28710 () | 128058..128402 | - | 345 | Protein_157 | IS6 family transposase IS26 | Transposase |
| HUS00_RS28715 () | 128454..129158 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HUS00_RS28720 () | 129222..129383 | + | 162 | Protein_159 | DNA helicase | - |
| HUS00_RS28725 () | 129403..130149 | + | 747 | WP_000205770.1 | conjugal transfer pilus acetylase TraX | - |
| HUS00_RS28730 () | 130204..130764 | + | 561 | WP_000139328.1 | fertility inhibition protein FinO | - |
| HUS00_RS28735 () | 130896..131096 | + | 201 | WP_015059022.1 | hypothetical protein | - |
| HUS00_RS28740 () | 131482..132081 | + | 600 | WP_032083981.1 | hypothetical protein | - |
| HUS00_RS28745 () | 132245..132475 | + | 231 | WP_001736714.1 | hypothetical protein | - |
| - () | 132676..132735 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 132676..132735 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 132676..132735 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 132676..132735 | - | 60 | NuclAT_1 | - | Antitoxin Detail |
| HUS00_RS28750 () | 132780..132929 | + | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| HUS00_RS28755 () | 133213..133461 | + | 249 | WP_000083837.1 | replication regulatory protein RepA | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|