MGE detailed information
MGE type: Conjugative plasmid MGE length: 144371 bp
Accession: NZ_CP050682 Location: 1..144371 Organism: Klebsiella variicola strain SHET-01 Replicon: plasmid pNDM-IMP-2
Accession: NZ_CP050682 Location: 1..144371 Organism: Klebsiella variicola strain SHET-01 Replicon: plasmid pNDM-IMP-2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HCO75_RS28405 (HCO75_28695) | 449..1039 | + | 591 | WP_052251507.1 | hypothetical protein | - |
| HCO75_RS28410 (HCO75_28700) | 1080..2219 | + | 1140 | WP_274757502.1 | MFS transporter | - |
| HCO75_RS28415 (HCO75_28705) | 2192..3421 | + | 1230 | WP_040107892.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| HCO75_RS28420 (HCO75_28710) | 3511..4671 | + | 1161 | WP_274757503.1 | aromatic amino acid transport family protein | - |
| HCO75_RS28425 (HCO75_28715) | 4716..6512 | + | 1797 | WP_063106365.1 | alpha-glucosidase | - |
| HCO75_RS28430 (HCO75_28720) | 7308..8453 | + | 1146 | WP_131011029.1 | ABC transporter permease | - |
| HCO75_RS28435 (HCO75_28725) | 8447..9247 | + | 801 | WP_040107888.1 | putative ribonucleotide transport ATP-binding protein mkl | VF |
| HCO75_RS28440 (HCO75_28730) | 9252..10190 | + | 939 | WP_055323524.1 | MlaD family protein | - |
| HCO75_RS28445 (HCO75_28735) | 10190..10834 | + | 645 | WP_055323523.1 | ABC-type transport auxiliary lipoprotein family protein | - |
| HCO75_RS28450 | 11054..11330 | - | 277 | Protein_9 | hypothetical protein | - |
| HCO75_RS28455 (HCO75_28745) | 12166..12837 | - | 672 | WP_055323522.1 | SOS response-associated peptidase | - |
| HCO75_RS28460 (HCO75_28750) | 13248..14243 | + | 996 | WP_063267100.1 | IS110 family transposase IS1663 | Transposase |
| HCO75_RS28465 (HCO75_28755) | 14471..15379 | - | 909 | WP_055323521.1 | Lipid A biosynthesis palmitoleoyltransferase | VF |
| HCO75_RS28470 | 15581..15853 | - | 273 | WP_171842335.1 | hypothetical protein | - |
| HCO75_RS28475 (HCO75_28765) | 16263..16496 | + | 234 | WP_004132711.1 | hypothetical protein | - |
| HCO75_RS28480 (HCO75_28770) | 16516..25098 | - | 8583 | WP_063267101.1 | Cyclic beta-(1,2)-glucan synthase NdvB | VF |
| HCO75_RS28485 | 25254..25418 | - | 165 | WP_213928491.1 | YnfU family zinc-binding protein | - |
| HCO75_RS28490 (HCO75_28775) | 25500..25712 | - | 213 | WP_071822061.1 | cold shock-like protein CspF | - |
| HCO75_RS28495 (HCO75_28780) | 25992..26210 | + | 219 | WP_023279058.1 | cold shock domain-containing protein | - |
| HCO75_RS28500 (HCO75_28785) | 26479..26706 | + | 228 | WP_040107967.1 | hypothetical protein | - |
| HCO75_RS28505 (HCO75_28790) | 27278..27683 | + | 406 | Protein_20 | H-NS family nucleoid-associated regulatory protein | - |
| HCO75_RS28510 (HCO75_28795) | 27761..27895 | + | 135 | Protein_21 | arsenical resistance protein ArsH | - |
| HCO75_RS28515 (HCO75_28800) | 28177..30786 | + | 2610 | WP_102803754.1 | AAA family ATPase | - |
| HCO75_RS28520 (HCO75_28805) | 31106..32089 | + | 984 | WP_219719227.1 | restriction endonuclease | - |
| HCO75_RS28525 (HCO75_28810) | 32858..33547 | + | 690 | WP_055323494.1 | YafY family protein | - |
| HCO75_RS28530 (HCO75_28815) | 33618..34364 | + | 747 | WP_055323493.1 | 3-oxoacyl-[acyl-carrier-protein] reductase FabG | VF |
| HCO75_RS28535 (HCO75_28820) | 34688..34915 | + | 228 | WP_012542191.1 | DUF1737 domain-containing protein | - |
| HCO75_RS28540 (HCO75_28825) | 35362..37125 | - | 1764 | WP_055323492.1 | putative signaling protein | VF |
| HCO75_RS28545 (HCO75_28830) | 38289..38594 | - | 306 | WP_049011000.1 | DUF596 domain-containing protein | - |
| HCO75_RS28550 (HCO75_28835) | 38674..44016 | - | 5343 | WP_274757504.1 | 16S rRNA endonuclease CdiA | VF |
| HCO75_RS28555 (HCO75_28840) | 44069..45745 | - | 1677 | WP_040107960.1 | Hemolysin transporter protein ShlB | VF |
| HCO75_RS28560 (HCO75_28855) | 46757..47614 | - | 858 | WP_040107958.1 | incFII family plasmid replication initiator RepA | - |
| HCO75_RS28565 (HCO75_28860) | 47607..47678 | - | 72 | WP_071786674.1 | RepA leader peptide Tap | - |
| HCO75_RS28570 (HCO75_28865) | 47893..48162 | - | 270 | WP_025712715.1 | replication regulatory protein RepA | - |
| HCO75_RS28575 (HCO75_28870) | 48286..48605 | - | 320 | Protein_34 | phospholipase D-like domain-containing protein | - |
| HCO75_RS28580 (HCO75_28875) | 48676..50859 | - | 2184 | WP_040107957.1 | peptidase domain-containing ABC transporter | - |
| HCO75_RS28585 (HCO75_28880) | 50859..52112 | - | 1254 | WP_040107998.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
| HCO75_RS28590 (HCO75_28885) | 52115..52615 | - | 501 | WP_264972564.1 | CPBP family intramembrane metalloprotease | - |
| HCO75_RS28595 (HCO75_28890) | 52987..53361 | - | 375 | WP_071826202.1 | hypothetical protein | - |
| HCO75_RS28600 (HCO75_28895) | 54047..54394 | - | 348 | WP_040107955.1 | DUF6404 family protein | - |
| HCO75_RS28605 (HCO75_28900) | 54414..55010 | - | 597 | WP_040107954.1 | fertility inhibition protein FinO | - |
| HCO75_RS28610 (HCO75_28905) | 55082..55807 | - | 726 | WP_040107953.1 | type-F conjugative transfer system pilin acetylase TraX | - |
| HCO75_RS28615 (HCO75_28910) | 55897..61158 | - | 5262 | WP_274757505.1 | Multifunctional conjugation protein TraI | Relaxase |
| HCO75_RS28620 (HCO75_28915) | 61158..63467 | - | 2310 | WP_274757506.1 | type IV conjugative transfer system coupling protein TraD | - |
| HCO75_RS28625 (HCO75_28920) | 63690..64376 | - | 687 | WP_145940812.1 | Secretory immunoglobulin A-binding protein EsiB | VF |
| HCO75_RS28630 (HCO75_28925) | 64409..65047 | - | 639 | WP_145940811.1 | hypothetical protein | - |
| HCO75_RS28635 (HCO75_28930) | 65072..67924 | - | 2853 | WP_274757507.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| HCO75_RS28640 (HCO75_28935) | 67924..69273 | - | 1350 | WP_040107994.1 | conjugal transfer pilus assembly protein TraH | - |
| HCO75_RS28645 (HCO75_28940) | 69739..70287 | - | 549 | WP_040107946.1 | hypothetical protein | - |
| HCO75_RS28650 (HCO75_28945) | 70277..70852 | - | 576 | WP_274757508.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| HCO75_RS28655 (HCO75_28950) | 70824..71063 | - | 240 | WP_004152687.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| HCO75_RS28660 (HCO75_28955) | 71074..71826 | - | 753 | WP_040107944.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| HCO75_RS28665 (HCO75_28960) | 71847..72173 | - | 327 | WP_040107943.1 | hypothetical protein | - |
| HCO75_RS28670 (HCO75_28965) | 72184..72411 | - | 228 | WP_040107941.1 | conjugal transfer protein TrbE | - |
| HCO75_RS28675 (HCO75_28970) | 72401..72682 | - | 282 | WP_040107939.1 | hypothetical protein | - |
| HCO75_RS28680 (HCO75_28975) | 72715..74670 | - | 1956 | WP_040107938.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| HCO75_RS28685 (HCO75_28980) | 74736..75374 | - | 639 | WP_040107937.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| HCO75_RS28690 (HCO75_28985) | 75387..76376 | - | 990 | WP_274757490.1 | conjugal transfer pilus assembly protein TraU | - |
| HCO75_RS28695 (HCO75_28990) | 76373..76762 | - | 390 | WP_040107935.1 | hypothetical protein | - |
| HCO75_RS28700 (HCO75_28995) | 76804..77430 | - | 627 | WP_231669556.1 | type-F conjugative transfer system protein TraW | - |
| HCO75_RS28705 (HCO75_29000) | 77430..77819 | - | 390 | WP_040107933.1 | type-F conjugative transfer system protein TrbI | - |
| HCO75_RS28710 (HCO75_29005) | 77819..80458 | - | 2640 | WP_040107932.1 | type IV secretion system protein TraC | - |
| HCO75_RS28715 (HCO75_29010) | 80530..80928 | - | 399 | WP_162493351.1 | hypothetical protein | - |
| HCO75_RS28720 | 80936..81259 | - | 324 | WP_040107930.1 | hypothetical protein | - |
| HCO75_RS28725 (HCO75_29020) | 81302..81706 | - | 405 | WP_032740694.1 | hypothetical protein | - |
| HCO75_RS28730 (HCO75_29025) | 81773..82084 | - | 312 | WP_040107929.1 | hypothetical protein | - |
| HCO75_RS28735 (HCO75_29030) | 82085..82303 | - | 219 | WP_004195468.1 | hypothetical protein | - |
| HCO75_RS28740 (HCO75_29035) | 82327..82617 | - | 291 | WP_040107928.1 | hypothetical protein | - |
| HCO75_RS28745 | 82646..83044 | - | 399 | WP_227514785.1 | hypothetical protein | - |
| HCO75_RS28750 (HCO75_29045) | 83199..83768 | - | 570 | WP_071983369.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HCO75_RS28755 (HCO75_29050) | 83788..83949 | - | 162 | WP_158514515.1 | hypothetical protein | - |
| HCO75_RS28760 (HCO75_29055) | 83986..84399 | - | 414 | Protein_71 | conjugal transfer pilus-stabilizing protein TraP | - |
| HCO75_RS28765 (HCO75_29060) | 84392..85816 | - | 1425 | WP_040107926.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| HCO75_RS28770 (HCO75_29065) | 85816..86556 | - | 741 | WP_040107925.1 | type-F conjugative transfer system secretin TraK | - |
| HCO75_RS28775 (HCO75_29070) | 86543..87109 | - | 567 | WP_040107924.1 | type IV conjugative transfer system protein TraE | - |
| HCO75_RS28780 (HCO75_29075) | 87129..87434 | - | 306 | WP_004178059.1 | type IV conjugative transfer system protein TraL | - |
| HCO75_RS28785 (HCO75_29080) | 87448..87816 | - | 369 | WP_040107923.1 | type IV conjugative transfer system pilin TraA | - |
| HCO75_RS28790 (HCO75_29085) | 87878..88084 | - | 207 | WP_172412524.1 | TraY domain-containing protein | - |
| HCO75_RS28795 (HCO75_29090) | 88217..88936 | - | 720 | WP_158514514.1 | conjugal transfer protein TrbJ | - |
| HCO75_RS28800 (HCO75_29095) | 89136..89552 | - | 417 | WP_074181767.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| HCO75_RS28805 (HCO75_29100) | 90015..90422 | + | 408 | WP_223170089.1 | hypothetical protein | VF |
| HCO75_RS28810 (HCO75_29105) | 90460..90990 | - | 531 | WP_023292160.1 | antirestriction protein | - |
| HCO75_RS28815 (HCO75_29110) | 91615..92448 | - | 834 | WP_046622825.1 | N-6 DNA methylase | - |
| HCO75_RS28820 (HCO75_29115) | 92495..92725 | - | 231 | WP_038990977.1 | hypothetical protein | - |
| HCO75_RS28825 (HCO75_29120) | 92813..93160 | - | 348 | WP_274757491.1 | hypothetical protein | - |
| HCO75_RS28830 (HCO75_29125) | 93227..93607 | - | 381 | WP_038990973.1 | hypothetical protein | - |
| HCO75_RS28835 (HCO75_29130) | 94512..94631 | - | 120 | WP_223156217.1 | type I toxin-antitoxin system Hok family toxin | - |
| HCO75_RS28840 | 94576..94728 | - | 153 | WP_224230667.1 | DUF5431 family protein | - |
| HCO75_RS28845 (HCO75_29135) | 94887..95213 | - | 327 | WP_038992719.1 | hypothetical protein | - |
| HCO75_RS28850 (HCO75_29140) | 95210..95938 | - | 729 | WP_274757492.1 | plasmid SOS inhibition protein A | - |
| HCO75_RS28855 (HCO75_29145) | 95935..96366 | - | 432 | WP_038992715.1 | conjugation system SOS inhibitor PsiB | - |
| HCO75_RS28860 (HCO75_29150) | 96411..98411 | - | 2001 | WP_110188596.1 | ParB/RepB/Spo0J family partition protein | - |
| HCO75_RS28865 (HCO75_29155) | 98480..98728 | - | 249 | WP_040107914.1 | DUF905 domain-containing protein | - |
| HCO75_RS28870 (HCO75_29160) | 98777..99319 | - | 543 | WP_274757493.1 | single-stranded DNA-binding protein | - |
| HCO75_RS28875 | 99350..99553 | - | 204 | WP_071592596.1 | hypothetical protein | - |
| HCO75_RS28880 (HCO75_29175) | 99988..100308 | - | 321 | WP_023340975.1 | hypothetical protein | - |
| HCO75_RS28885 (HCO75_29180) | 100343..100597 | - | 255 | WP_274757494.1 | DNA polymerase III subunit theta | - |
| HCO75_RS28890 (HCO75_29185) | 100798..100989 | - | 192 | WP_040107911.1 | hypothetical protein | - |
| HCO75_RS28895 (HCO75_29190) | 101032..101538 | - | 507 | WP_046622857.1 | antirestriction protein ArdA | - |
| HCO75_RS28900 (HCO75_29195) | 101583..102011 | - | 429 | WP_040107910.1 | antirestriction protein | - |
| HCO75_RS28905 | 102459..102623 | - | 165 | Protein_100 | hypothetical protein | - |
| HCO75_RS28910 (HCO75_29200) | 102639..104210 | - | 1572 | WP_055323516.1 | sensor domain-containing diguanylate cyclase | - |
| HCO75_RS28915 (HCO75_29205) | 104621..104917 | + | 297 | WP_042937695.1 | hypothetical protein | - |
| HCO75_RS28920 (HCO75_29210) | 105308..105538 | - | 231 | WP_032740680.1 | hypothetical protein | - |
| HCO75_RS28925 (HCO75_29215) | 105997..106899 | + | 903 | WP_040107984.1 | DHH family phosphoesterase | - |
| HCO75_RS28930 (HCO75_29220) | 106902..107327 | + | 426 | WP_032740679.1 | universal stress protein | - |
| HCO75_RS28935 (HCO75_29225) | 107344..108633 | + | 1290 | WP_032740678.1 | phosphopyruvate hydratase | - |
| HCO75_RS28940 (HCO75_29230) | 108730..109104 | + | 375 | WP_100245397.1 | fluoride efflux transporter CrcB | - |
| HCO75_RS28945 (HCO75_29235) | 109838..110803 | - | 966 | WP_032740676.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HCO75_RS28950 (HCO75_29240) | 110803..111969 | - | 1167 | WP_000523815.1 | Sporulation initiation inhibitor protein Soj | VF |
| HCO75_RS28955 (HCO75_29245) | 112711..113721 | + | 1011 | WP_032740675.1 | RepB family plasmid replication initiator protein | - |
| HCO75_RS28960 (HCO75_29250) | 114504..115244 | - | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| HCO75_RS28965 (HCO75_29255) | 115363..115485 | - | 123 | Protein_112 | serine/threonine protein kinase | - |
| HCO75_RS28970 (HCO75_29260) | 115566..115706 | - | 141 | Protein_113 | site-specific integrase | - |
| HCO75_RS28975 (HCO75_29265) | 115729..118848 | - | 3120 | WP_274757495.1 | SIR2 family protein | - |
| HCO75_RS28980 (HCO75_29270) | 119159..119290 | + | 132 | Protein_115 | IS3 family transposase | - |
| HCO75_RS28985 (HCO75_29275) | 119382..120176 | - | 795 | WP_274757496.1 | site-specific integrase | - |
| HCO75_RS28990 (HCO75_29280) | 120244..120897 | - | 654 | WP_274757497.1 | hypothetical protein | - |
| HCO75_RS28995 (HCO75_29285) | 121835..124516 | + | 2682 | WP_274757498.1 | DNA repair protein | - |
| HCO75_RS29000 (HCO75_29290) | 124795..125043 | + | 249 | WP_128206213.1 | hypothetical protein | - |
| HCO75_RS29005 (HCO75_29295) | 125040..125612 | + | 573 | WP_080929385.1 | hypothetical protein | - |
| HCO75_RS29010 (HCO75_29300) | 125643..126134 | + | 492 | WP_114473040.1 | DNA-binding protein | - |
| HCO75_RS29015 (HCO75_29305) | 126142..126252 | + | 111 | Protein_122 | IS5/IS1182 family transposase | - |
| HCO75_RS29020 (HCO75_29310) | 126327..127544 | - | 1218 | WP_080929383.1 | MFS transporter | - |
| HCO75_RS29025 (HCO75_29315) | 127541..128227 | - | 687 | WP_042936835.1 | DJ-1/PfpI family protein | - |
| HCO75_RS29030 (HCO75_29320) | 128245..128994 | - | 750 | WP_049010622.1 | class I SAM-dependent methyltransferase | - |
| HCO75_RS29035 (HCO75_29325) | 129011..130342 | - | 1332 | WP_274757499.1 | hypothetical protein | - |
| HCO75_RS29040 (HCO75_29330) | 130335..131786 | - | 1452 | WP_046622880.1 | L-tyrosine/L-tryptophan isonitrile synthase family protein | - |
| HCO75_RS29045 (HCO75_29335) | 132028..133059 | + | 1032 | WP_274757509.1 | GlxA family transcriptional regulator | - |
| HCO75_RS29050 (HCO75_29340) | 133110..133272 | + | 163 | Protein_129 | type I toxin-antitoxin system Hok family toxin | - |
| HCO75_RS29055 (HCO75_29345) | 133441..133728 | - | 288 | WP_046622894.1 | Isochorismate pyruvate lyase | VF |
| HCO75_RS29060 (HCO75_29350) | 133877..134710 | - | 834 | WP_274757500.1 | hypothetical protein | - |
| HCO75_RS29065 (HCO75_29355) | 135031..135297 | + | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| HCO75_RS29070 (HCO75_29360) | 135285..135767 | + | 483 | WP_274757501.1 | GNAT family N-acetyltransferase | Toxin Detail |
| HCO75_RS29075 (HCO75_29365) | 135983..137383 | + | 1401 | WP_131024503.1 | ISNCY family transposase ISKpn21 | Transposase |
| HCO75_RS29080 (HCO75_29370) | 137571..137990 | + | 420 | WP_012540023.1 | ASCH domain-containing protein | - |
| HCO75_RS29085 (HCO75_29375) | 138572..139573 | + | 1002 | WP_040107896.1 | LacI family DNA-binding transcriptional regulator | - |
| HCO75_RS29090 (HCO75_29380) | 139621..141303 | + | 1683 | WP_040107895.1 | alpha-glucosidase | - |
| HCO75_RS29095 (HCO75_29385) | 141296..142687 | + | 1392 | WP_063106368.1 | PTS transporter subunit EIIC | - |
| HCO75_RS29100 (HCO75_29390) | 142931..144295 | + | 1365 | WP_226648963.1 | carbohydrate porin | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|