MGE detailed information
MGE type: Conjugative plasmid MGE length: 127925 bp
Accession: NZ_CP050373 Location: 1..127925 Organism: Klebsiella pneumoniae strain 50595 Replicon: plasmid p50595_IncFII
Accession: NZ_CP050373 Location: 1..127925 Organism: Klebsiella pneumoniae strain 50595 Replicon: plasmid p50595_IncFII
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HB637_RS27365 () | 1..464 | - | 464 | Protein_0 | multicopper oxidase PcoA | - |
| HB637_RS27370 () | 698..1147 | + | 450 | WP_001023257.1 | copper resistance protein | - |
| HB637_RS27375 () | 1436..2173 | + | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| HB637_RS27380 () | 2207..2404 | - | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| HB637_RS27385 () | 2445..4892 | - | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| HB637_RS27390 () | 5019..5459 | - | 441 | WP_000758228.1 | hypothetical protein | - |
| HB637_RS27395 () | 5546..8692 | - | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| HB637_RS27400 () | 8703..9995 | - | 1293 | WP_004152079.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| HB637_RS27405 () | 10109..10462 | - | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| HB637_RS27410 () | 10491..11876 | - | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| HB637_RS27415 () | 12066..12746 | + | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| HB637_RS27420 () | 12739..14214 | + | 1476 | WP_003032875.1 | copper/silver sensor histidine kinase SilS | - |
| HB637_RS27425 () | 14465..14896 | + | 432 | WP_004178091.1 | silver-binding protein SilE | - |
| HB637_RS27430 () | 15192..15734 | - | 543 | Protein_13 | ISL3 family transposase ISKpn25 | Transposase |
| HB637_RS27435 () | 15750..16234 | - | 485 | Protein_14 | IS1 family transposase IS1X2 | Transposase |
| HB637_RS27440 () | 16325..17532 | + | 1208 | WP_085955172.1 | IS3 family transposase ISEcl1 | Transposase |
| HB637_RS27445 () | 17723..18420 | + | 698 | Protein_16 | IS1 family transposase IS1X2 | Transposase |
| HB637_RS27450 () | 18572..20569 | + | 1998 | WP_004178088.1 | choline BCCT transporter BetT | - |
| HB637_RS27455 () | 20632..21909 | + | 1278 | WP_004152070.1 | DUF2254 domain-containing protein | - |
| HB637_RS27460 () | 22892..24328 | - | 1437 | WP_080895248.1 | putative cyclic di-GMP phosphodiesterase PdeB | VF |
| HB637_RS27465 () | 24948..25205 | + | 258 | WP_004197688.1 | hypothetical protein | - |
| HB637_RS27470 () | 25878..26846 | - | 969 | WP_011977741.1 | IS5 family transposase IS903B | Transposase |
| HB637_RS27475 () | 26866..27177 | + | 312 | WP_071527918.1 | EAL domain-containing protein | - |
| HB637_RS27480 () | 27204..28151 | - | 948 | WP_004152065.1 | sensor domain-containing diguanylate cyclase | - |
| HB637_RS27485 () | 29295..30035 | + | 741 | WP_001515717.1 | tyrosine-type recombinase/integrase | - |
| HB637_RS27490 () | 30752..31762 | - | 1011 | WP_000200070.1 | RepB family plasmid replication initiator protein | - |
| HB637_RS27495 () | 32514..33680 | + | 1167 | WP_000523813.1 | Sporulation initiation inhibitor protein Soj | VF |
| HB637_RS27500 () | 33680..34651 | + | 972 | WP_004152062.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| HB637_RS27505 () | 35960..37158 | + | 1199 | Protein_28 | IS200-IS605 family transposase IS609 | Transposase |
| HB637_RS27510 () | 37181..37396 | - | 216 | Protein_29 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| HB637_RS27515 () | 37475..38746 | - | 1272 | WP_014386156.1 | Y-family DNA polymerase | - |
| HB637_RS27520 () | 38746..39171 | - | 426 | WP_004182047.1 | translesion error-prone DNA polymerase V autoproteolytic subunit | - |
| HB637_RS27525 () | 39272..40492 | + | 1221 | WP_000343760.1 | ISL3 family transposase ISKox3 | Transposase |
| HB637_RS27530 () | 40710..40940 | + | 231 | WP_004118481.1 | hypothetical protein | - |
| HB637_RS27535 () | 41461..41886 | + | 426 | WP_004118478.1 | antirestriction protein | - |
| HB637_RS27540 () | 42123..42377 | + | 255 | WP_004152754.1 | DNA polymerase III subunit theta | - |
| HB637_RS27545 () | 42412..42729 | + | 318 | WP_004118473.1 | hypothetical protein | - |
| HB637_RS27560 () | 43510..43737 | + | 228 | WP_004178072.1 | hypothetical protein | - |
| HB637_RS27565 () | 43829..44059 | + | 231 | WP_001568051.1 | hypothetical protein | - |
| HB637_RS27570 () | 44111..45466 | + | 1356 | WP_004178068.1 | DUF3560 domain-containing protein | - |
| HB637_RS27575 () | 45514..46077 | + | 564 | WP_004152645.1 | methyltransferase | - |
| HB637_RS27585 () | 46853..47395 | + | 543 | WP_004152644.1 | single-stranded DNA-binding protein | - |
| HB637_RS27590 () | 47444..47692 | + | 249 | WP_004152643.1 | DUF905 domain-containing protein | - |
| HB637_RS27595 () | 47762..49798 | + | 2037 | WP_004178066.1 | ParB/RepB/Spo0J family partition protein | - |
| HB637_RS27600 () | 49865..50296 | + | 432 | WP_004152641.1 | conjugation system SOS inhibitor PsiB | - |
| HB637_RS27605 () | 50293..51021 | + | 729 | WP_004152640.1 | plasmid SOS inhibition protein A | - |
| HB637_RS27610 () | 51018..51344 | + | 327 | WP_004152639.1 | hypothetical protein | - |
| HB637_RS27615 () | 51400..51774 | + | 375 | WP_004152638.1 | hypothetical protein | - |
| HB637_RS27620 () | 52002..52163 | + | 162 | WP_004118124.1 | type I toxin-antitoxin system Hok family toxin | - |
| HB637_RS27635 () | 52863..53135 | + | 273 | WP_004152759.1 | hypothetical protein | - |
| HB637_RS27640 () | 53132..53482 | + | 351 | WP_004152758.1 | hypothetical protein | - |
| HB637_RS27655 () | 54118..54474 | + | 357 | WP_004152717.1 | hypothetical protein | - |
| HB637_RS27660 () | 54535..54747 | + | 213 | WP_004152718.1 | hypothetical protein | - |
| HB637_RS27665 () | 54758..54982 | + | 225 | WP_004152719.1 | hypothetical protein | - |
| HB637_RS27670 () | 55063..55383 | + | 321 | WP_004152720.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HB637_RS27675 () | 55373..55651 | + | 279 | WP_004152721.1 | helix-turn-helix domain-containing protein | - |
| HB637_RS27680 () | 55652..56065 | + | 414 | WP_004152722.1 | helix-turn-helix domain-containing protein | - |
| HB637_RS27700 () | 56899..57720 | + | 822 | WP_004178064.1 | DUF945 domain-containing protein | - |
| HB637_RS27705 () | 57753..58082 | + | 330 | WP_011977736.1 | hypothetical protein | - |
| HB637_RS27710 () | 58115..58600 | - | 486 | WP_004178063.1 | hypothetical protein | VF |
| HB637_RS27715 () | 59034..59426 | + | 393 | WP_004178062.1 | relaxosome protein TraM | - |
| HB637_RS27720 () | 59649..60335 | + | 687 | WP_011977735.1 | transcriptional regulator TraJ family protein | - |
| HB637_RS27725 () | 60419..60790 | + | 372 | WP_004208838.1 | TraY domain-containing protein | - |
| HB637_RS27730 () | 60844..61212 | + | 369 | WP_004178060.1 | type IV conjugative transfer system pilin TraA | - |
| HB637_RS27735 () | 61226..61531 | + | 306 | WP_004178059.1 | type IV conjugative transfer system protein TraL | - |
| HB637_RS27740 () | 61551..62117 | + | 567 | WP_004152602.1 | type IV conjugative transfer system protein TraE | - |
| HB637_RS27745 () | 62104..62844 | + | 741 | WP_004152601.1 | type-F conjugative transfer system secretin TraK | - |
| HB637_RS27750 () | 62844..64268 | + | 1425 | WP_004152600.1 | conjugal transfer protein TraB | - |
| HB637_RS27755 () | 64261..64857 | + | 597 | WP_004152599.1 | conjugal transfer protein TraP | - |
| HB637_RS27760 () | 64880..65449 | + | 570 | WP_004152598.1 | type IV conjugative transfer system lipoprotein TraV | - |
| HB637_RS27765 () | 65581..65991 | + | 411 | WP_004152597.1 | lipase chaperone | - |
| HB637_RS27770 () | 65996..66286 | + | 291 | WP_004152596.1 | hypothetical protein | - |
| HB637_RS27775 () | 66310..66528 | + | 219 | WP_004171484.1 | hypothetical protein | - |
| HB637_RS27780 () | 66529..66846 | + | 318 | WP_004152595.1 | hypothetical protein | - |
| HB637_RS27785 () | 66913..67317 | + | 405 | WP_004152594.1 | hypothetical protein | - |
| HB637_RS27790 () | 67613..68011 | + | 399 | WP_004153071.1 | hypothetical protein | - |
| HB637_RS27795 () | 68083..70722 | + | 2640 | WP_004152592.1 | type IV secretion system protein TraC | - |
| HB637_RS27800 () | 70722..71111 | + | 390 | WP_004152591.1 | type-F conjugative transfer system protein TrbI | - |
| HB637_RS27805 () | 71111..71737 | + | 627 | WP_004152590.1 | type-F conjugative transfer system protein TraW | - |
| HB637_RS27810 () | 71781..72143 | + | 363 | Protein_79 | TraU family protein | - |
| HB637_RS27815 () | 72207..72911 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HB637_RS27820 () | 73167..73487 | + | 321 | WP_015632449.1 | hypothetical protein | - |
| HB637_RS27825 () | 73758..74090 | - | 333 | WP_015632448.1 | hypothetical protein | - |
| HB637_RS27830 () | 74486..74797 | + | 312 | WP_016162079.1 | hypothetical protein | - |
| HB637_RS27835 () | 74800..76728 | + | 1929 | WP_015632446.1 | Protein TraI | Relaxase |
| HB637_RS27840 () | 76769..77020 | - | 252 | WP_016162080.1 | hypothetical protein | - |
| HB637_RS27845 () | 77032..77289 | - | 258 | WP_016162081.1 | Phospholipase D | VF |
| HB637_RS27850 () | 77365..77772 | + | 408 | WP_015632445.1 | IS66 family transposase ISCro1 | Transposase |
| HB637_RS27855 () | 77769..78107 | + | 339 | WP_032495749.1 | IS66 family transposase IS682 | Transposase |
| HB637_RS27860 () | 78148..79737 | + | 1590 | WP_015632444.1 | IS66 family transposase ISEcl6 | Transposase |
| HB637_RS27865 () | 79760..80065 | - | 306 | WP_015632443.1 | hypothetical protein | - |
| HB637_RS27870 () | 80111..82303 | - | 2193 | WP_015632442.1 | hypothetical protein | VF |
| HB637_RS27875 () | 82305..83432 | - | 1128 | WP_157787237.1 | thioredoxin fold domain-containing protein | - |
| HB637_RS27880 () | 83407..84825 | - | 1419 | WP_015632440.1 | hypothetical protein | - |
| HB637_RS27885 () | 84927..85550 | - | 624 | WP_015632439.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| HB637_RS27890 () | 85616..87760 | - | 2145 | WP_015632438.1 | DotA/TraY family protein | - |
| HB637_RS27895 () | 87802..88383 | - | 582 | WP_015632437.1 | conjugal transfer protein TraX | - |
| HB637_RS27900 () | 88380..89576 | - | 1197 | WP_015632436.1 | conjugal transfer protein TraW | - |
| HB637_RS27905 () | 89587..92634 | - | 3048 | WP_015632435.1 | conjugal transfer protein | - |
| HB637_RS27910 () | 92644..92958 | - | 315 | WP_123677146.1 | hypothetical protein | - |
| HB637_RS27915 () | 93251..93652 | - | 402 | WP_015632433.1 | hypothetical protein | - |
| HB637_RS27920 () | 93706..94239 | - | 534 | WP_015632432.1 | conjugal transfer protein TraQ | - |
| HB637_RS27925 () | 94249..94968 | - | 720 | WP_015632431.1 | conjugal transfer protein TraP | - |
| HB637_RS27930 () | 94974..96314 | - | 1341 | WP_015632430.1 | conjugal transfer protein TraO | - |
| HB637_RS27935 () | 96318..97421 | - | 1104 | WP_015632429.1 | conjugal transfer protein | - |
| HB637_RS27940 () | 97432..98136 | - | 705 | WP_015632428.1 | DotI/IcmL/TraM family protein | - |
| HB637_RS27945 () | 98172..98525 | - | 354 | WP_015632427.1 | hypothetical protein | - |
| HB637_RS27950 () | 98559..101882 | - | 3324 | WP_032495745.1 | DNA primase TraC | VF |
| HB637_RS27955 () | 101900..102166 | - | 267 | WP_032441926.1 | hypothetical protein | VF |
| HB637_RS27960 () | 102163..103350 | - | 1188 | WP_032495744.1 | putative protein YggR | VF |
| HB637_RS27965 () | 103328..104146 | - | 819 | WP_015632425.1 | hypothetical protein | VF |
| HB637_RS27970 () | 104143..104610 | - | 468 | WP_015632424.1 | DotD/TraH family lipoprotein | - |
| HB637_RS27975 () | 104633..105112 | - | 480 | WP_015632423.1 | hypothetical protein | VF |
| HB637_RS27980 () | 105810..106121 | - | 312 | WP_015632421.1 | hypothetical protein | - |
| HB637_RS27985 () | 106155..106358 | - | 204 | WP_032495743.1 | hypothetical protein | - |
| HB637_RS27990 () | 106376..106909 | - | 534 | WP_015632420.1 | hypothetical protein | - |
| HB637_RS27995 () | 107177..107755 | + | 579 | WP_015632419.1 | hypothetical protein | - |
| HB637_RS28000 () | 107737..108207 | + | 471 | WP_032441927.1 | hypothetical protein | - |
| HB637_RS28005 () | 108207..108593 | + | 387 | WP_015632417.1 | acyl-CoA thioesterase | - |
| HB637_RS28010 () | 108977..109678 | + | 702 | WP_157948106.1 | RepA protein | - |
| HB637_RS28015 () | 110624..110959 | - | 336 | WP_011977766.1 | C2H2-type zinc finger protein | - |
| HB637_RS28020 () | 111132..111413 | + | 282 | WP_001568067.1 | hypothetical protein | - |
| HB637_RS28025 () | 111467..112078 | + | 612 | WP_000176305.1 | DUF2913 family protein | - |
| HB637_RS28030 () | 112075..112236 | - | 162 | WP_001326844.1 | hypothetical protein | - |
| HB637_RS28035 () | 112263..113255 | - | 993 | WP_001145103.1 | hypothetical protein | - |
| HB637_RS28040 () | 113304..113459 | - | 156 | WP_000075580.1 | hypothetical protein | - |
| HB637_RS28045 () | 113600..114304 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| HB637_RS28050 () | 114344..114806 | - | 463 | Protein_127 | IS481 family transposase ISKpn28 | Transposase |
| HB637_RS28055 () | 115037..115129 | + | 93 | Protein_128 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HB637_RS28060 () | 115293..116681 | - | 1389 | WP_014386175.1 | sugar porter family MFS transporter | - |
| HB637_RS28065 () | 116713..117624 | - | 912 | WP_014386176.1 | ROK family protein | - |
| HB637_RS28070 () | 117621..118634 | - | 1014 | WP_014386177.1 | SIS domain-containing protein | - |
| HB637_RS28075 () | 118862..119617 | + | 756 | WP_032408898.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| HB637_RS28080 () | 119879..120319 | + | 441 | WP_014386179.1 | IS66 family transposase ISKox1 | Transposase |
| HB637_RS28085 () | 120316..120666 | + | 351 | WP_014386180.1 | IS66 family transposase ISKox1 | Transposase |
| HB637_RS28090 () | 120697..122289 | + | 1593 | Protein_135 | IS66 family transposase ISEcl6 | Transposase |
| HB637_RS28095 () | 122486..122737 | + | 252 | WP_032408900.1 | aldo/keto reductase | - |
| HB637_RS28100 () | 123178..123669 | - | 492 | WP_032408901.1 | GNAT family N-acetyltransferase | Toxin Detail |
| HB637_RS28105 () | 123657..123923 | - | 267 | WP_014386183.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| HB637_RS28110 () | 124120..124278 | + | 159 | WP_014386184.1 | type I toxin-antitoxin system Hok family toxin | - |
| HB637_RS28115 () | 124522..125007 | - | 486 | WP_014386185.1 | hypothetical protein | - |
| HB637_RS28120 () | 125197..125469 | + | 273 | WP_032408902.1 | hypothetical protein | - |
| HB637_RS28125 () | 125466..125816 | + | 351 | WP_014386186.1 | hypothetical protein | - |
| HB637_RS28140 () | 126453..126779 | + | 327 | WP_014386187.1 | hypothetical protein | - |
| HB637_RS28145 () | 126841..127053 | + | 213 | WP_014386188.1 | hypothetical protein | - |
| HB637_RS28150 () | 127064..127288 | + | 225 | WP_014386189.1 | hypothetical protein | - |
| HB637_RS28155 () | 127369..127683 | + | 315 | Protein_146 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| HB637_RS28160 () | 127737..127925 | - | 189 | WP_000330527.1 | IS6 family transposase IS15DI | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|