MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 97111 bp
Accession: NZ_CP048345 Location: 1..97111 Organism: Escherichia coli strain 124 Replicon: plasmid p124_A
Accession: NZ_CP048345 Location: 1..97111 Organism: Escherichia coli strain 124 Replicon: plasmid p124_A
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GZS11_RS22665 () | 1..978 | + | 978 | WP_000361610.1 | RepB family plasmid replication initiator protein | - |
| GZS11_RS22670 () | 1263..2003 | - | 741 | WP_001066942.1 | tyrosine-type recombinase/integrase | - |
| GZS11_RS22675 () | 2124..2306 | - | 183 | WP_042065278.1 | hypothetical protein | - |
| GZS11_RS22680 () | 2649..2956 | - | 308 | Protein_3 | type II toxin-antitoxin system ParD family antitoxin | - |
| GZS11_RS22685 () | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| GZS11_RS22690 () | 4651..4779 | + | 129 | Protein_5 | IS481 family transposase | - |
| GZS11_RS22695 () | 4814..5008 | - | 195 | WP_086258557.1 | hypothetical protein | - |
| GZS11_RS22700 () | 5050..5747 | + | 698 | Protein_7 | IS1 family transposase IS1R | Transposase |
| GZS11_RS22705 () | 5763..5882 | + | 120 | Protein_8 | ArsR family transcriptional regulator | - |
| GZS11_RS22710 () | 5860..6483 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| GZS11_RS22715 () | 6565..7770 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| GZS11_RS22720 () | 7883..8476 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| GZS11_RS22725 () | 8610..9314 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GZS11_RS22730 () | 9368..9733 | - | 366 | Protein_13 | chromate transporter | - |
| GZS11_RS22735 () | 9889..10092 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| GZS11_RS22740 () | 10220..11059 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| GZS11_RS22745 () | 11053..11400 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| GZS11_RS22750 () | 11606..12394 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| GZS11_RS22755 () | 12525..12998 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| GZS11_RS22760 () | 13156..14169 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| GZS11_RS23935 () | 14372..14518 | + | 147 | Protein_20 | EAL domain-containing protein | - |
| GZS11_RS22770 () | 14591..15272 | - | 682 | Protein_21 | IS6 family transposase | - |
| GZS11_RS22775 () | 15429..15710 | - | 282 | Protein_22 | transposase zinc-binding domain-containing protein | - |
| GZS11_RS22780 () | 15856..16714 | - | 859 | Protein_23 | TEM family class A beta-lactamase | - |
| GZS11_RS22785 () | 16896..17086 | - | 191 | Protein_24 | helix-turn-helix domain-containing protein | - |
| GZS11_RS22790 () | 17150..17834 | + | 685 | Protein_25 | IS6 family transposase IS15DI | Transposase |
| GZS11_RS22795 () | 17888..18754 | - | 867 | WP_162676759.1 | IS4 family transposase IS10R | Transposase |
| GZS11_RS22800 () | 18864..19827 | - | 964 | Protein_27 | IS4 family transposase IS10R | Transposase |
| GZS11_RS22805 () | 19970..20830 | + | 861 | WP_000557454.1 | SPBc2 prophage-derived aminoglycoside N(3')-acetyltransferase-like protein YokD | ARG |
| GZS11_RS22810 () | 20843..21385 | + | 543 | WP_000587837.1 | AAA family ATPase | - |
| GZS11_RS22815 () | 21867..22058 | - | 192 | WP_000951934.1 | hypothetical protein | - |
| GZS11_RS22820 () | 22082..22309 | + | 228 | WP_000248278.1 | hypothetical protein | - |
| GZS11_RS22825 () | 22360..23487 | + | 1128 | WP_014837927.1 | DUF3883 domain-containing protein | - |
| GZS11_RS22830 () | 23524..24228 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GZS11_RS22835 () | 24350..25255 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| GZS11_RS22840 () | 25252..26490 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| GZS11_RS22845 () | 26490..27074 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| GZS11_RS22850 () | 27567..28331 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| GZS11_RS22855 () | 28459..29152 | + | 694 | Protein_38 | IS6 family transposase IS15DI | Transposase |
| GZS11_RS22860 () | 29316..29868 | + | 553 | Protein_39 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| GZS11_RS22865 () | 29997..30825 | + | 829 | Protein_40 | Beta-lactamase OXA-1 | ARG |
| GZS11_RS22870 () | 30961..31400 | + | 440 | Protein_41 | CatB-related O-acetyltransferase | - |
| GZS11_RS22875 () | 31454..32154 | - | 701 | Protein_42 | IS6 family transposase IS26 | Transposase |
| GZS11_RS22880 () | 32219..34462 | - | 2244 | Protein_43 | Tn3 family transposase TnpA_Tn3 | Transposase |
| GZS11_RS22885 () | 34476..34808 | + | 333 | WP_001393253.1 | WbuC family cupin fold metalloprotein | - |
| GZS11_RS22890 () | 34855..35730 | - | 876 | WP_000239590.1 | Beta-lactamase CTX-M-1 | ARG |
| GZS11_RS22895 () | 36131..36811 | - | 681 | Protein_46 | IS6 family transposase | - |
| GZS11_RS22900 () | 36875..37213 | + | 339 | Protein_47 | Tn3 family transposase TnpR_Tn3 | Transposase |
| GZS11_RS22905 () | 37396..38256 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| GZS11_RS22910 () | 38403..40874 | - | 2472 | Protein_49 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| GZS11_RS22915 () | 40877..41437 | - | 561 | WP_000147567.1 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| GZS11_RS22920 () | 41450..41770 | + | 321 | Protein_51 | IS1380 family transposase | - |
| GZS11_RS22925 () | 42010..42651 | + | 642 | WP_000134999.1 | MBL fold metallo-hydrolase | - |
| GZS11_RS23940 () | 42876..43547 | - | 672 | Protein_53 | Tn3 family transposase TnpA_ISPsy30 | Transposase |
| GZS11_RS22935 () | 43611..44315 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GZS11_RS22940 () | 44365..45084 | + | 720 | Protein_55 | AAA family ATPase | - |
| GZS11_RS22945 () | 45071..45922 | + | 852 | WP_000240536.1 | replication protein | - |
| GZS11_RS22955 () | 46230..47045 | + | 816 | WP_001043265.1 | Dihydropteroate synthase | ARG |
| GZS11_RS22960 () | 47106..47909 | + | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| GZS11_RS22965 () | 47909..48745 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| GZS11_RS22970 () | 48806..49507 | - | 702 | WP_203237408.1 | IS6 family transposase IS26 | Transposase |
| GZS11_RS23945 () | 49570..51869 | + | 2300 | Protein_61 | Tn3 family transposase | - |
| GZS11_RS23005 () | 52043..52444 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| GZS11_RS23010 () | 52377..52634 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| GZS11_RS23015 () | 52725..53055 | - | 331 | Protein_64 | CPBP family intramembrane metalloprotease | - |
| GZS11_RS23020 () | 53182..53376 | - | 195 | WP_148905645.1 | histidine phosphatase family protein | - |
| GZS11_RS23025 () | 54313..55169 | - | 857 | Protein_66 | incFII family plasmid replication initiator RepA | - |
| GZS11_RS23035 () | 55162..55236 | - | 75 | WP_031943482.1 | RepA leader peptide Tap | - |
| GZS11_RS23950 () | 55233..55366 | - | 134 | Protein_68 | protein CopA/IncA | - |
| GZS11_RS23040 () | 55597..57133 | + | 1537 | Protein_69 | IS21 family transposase | - |
| GZS11_RS23045 () | 57148..57892 | + | 745 | Protein_70 | IS21-like element ISEc12 family helper ATPase IstB | - |
| GZS11_RS23050 () | 58052..58306 | - | 255 | WP_162676766.1 | replication regulatory protein RepA | - |
| GZS11_RS23055 () | 58600..58734 | - | 135 | WP_023144756.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 58779..58839 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 58779..58839 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 58779..58839 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| - () | 58779..58839 | + | 61 | NuclAT_0 | - | Antitoxin Detail |
| GZS11_RS23060 () | 58806..59092 | - | 287 | Protein_73 | DUF2726 domain-containing protein | - |
| GZS11_RS23065 () | 59549..59815 | - | 267 | WP_162676767.1 | hypothetical protein | - |
| GZS11_RS23070 () | 59943..60503 | - | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| GZS11_RS23075 () | 60624..62422 | - | 1799 | Protein_76 | Multifunctional conjugation protein TraI | Relaxase |
| GZS11_RS23080 () | 62392..63474 | - | 1083 | WP_060621339.1 | DUF3560 domain-containing protein | - |
| GZS11_RS23085 () | 63526..63756 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| GZS11_RS23090 () | 64791..64982 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| GZS11_RS23095 () | 64979..65401 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| GZS11_RS23100 () | 65447..65749 | - | 303 | WP_001671341.1 | antirestriction protein | - |
| GZS11_RS23110 () | 66289..67065 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| GZS11_RS23115 () | 67116..67550 | - | 435 | WP_000274437.1 | DUF1380 family protein | - |
| GZS11_RS23120 () | 67564..67785 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| GZS11_RS23125 () | 67786..68469 | - | 684 | WP_000086185.1 | DNA methylase | - |
| GZS11_RS23130 () | 68546..68850 | - | 305 | Protein_86 | hypothetical protein | - |
| GZS11_RS23135 () | 68854..69756 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| GZS11_RS23140 () | 70623..71594 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| GZS11_RS23145 () | 71594..72760 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| GZS11_RS23150 () | 73348..74103 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| GZS11_RS23155 () | 74877..75683 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| GZS11_RS23160 () | 75684..75989 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| GZS11_RS23165 () | 75991..76209 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| GZS11_RS23170 () | 76843..77040 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| GZS11_RS23175 () | 77037..77321 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| GZS11_RS23180 () | 77341..78474 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| GZS11_RS23185 () | 78737..81856 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| GZS11_RS23190 () | 82163..82393 | + | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| GZS11_RS23195 () | 82390..82806 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| GZS11_RS23200 () | 82968..85106 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| GZS11_RS23205 () | 85571..86566 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| GZS11_RS23210 () | 86570..87502 | + | 933 | WP_000991832.1 | hypothetical protein | - |
| GZS11_RS23215 () | 87639..88336 | - | 698 | Protein_103 | IS1 family transposase IS1R | Transposase |
| GZS11_RS23220 () | 88550..91666 | - | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| GZS11_RS23225 () | 91788..93071 | - | 1284 | WP_001617890.1 | restriction endonuclease subunit S | - |
| GZS11_RS23230 () | 93068..94624 | - | 1557 | WP_001553856.1 | type I restriction-modification system subunit M | - |
| GZS11_RS23235 () | 94807..95028 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| GZS11_RS23240 () | 95028..95408 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| GZS11_RS23245 () | 95413..95592 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| GZS11_RS23250 () | 95620..95979 | + | 360 | WP_001513660.1 | hypothetical protein | - |
| GZS11_RS23255 () | 95903..96316 | + | 414 | Protein_111 | IS3 family transposase ISLad1 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|