MGE detailed information
MGE type: Conjugative plasmid MGE length: 135123 bp
Accession: NZ_CP047878 Location: 1..135123 Organism: Escherichia coli strain LD22-1 Replicon: plasmid pLD22-1-135kb
Accession: NZ_CP047878 Location: 1..135123 Organism: Escherichia coli strain LD22-1 Replicon: plasmid pLD22-1-135kb
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GUU87_RS24200 () | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| GUU87_RS24205 () | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| GUU87_RS24210 () | 2124..2312 | - | 189 | WP_065203495.1 | serine/threonine protein kinase | - |
| GUU87_RS24215 () | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| GUU87_RS24220 () | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| GUU87_RS24225 () | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| GUU87_RS24230 () | 7426..7584 | - | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| GUU87_RS24235 () | 7768..8967 | + | 1200 | Protein_7 | IS3 family transposase IS629 | Transposase |
| GUU87_RS24245 () | 9115..9440 | - | 326 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| GUU87_RS24250 () | 10421..11608 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| GUU87_RS24255 () | 11605..13545 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| GUU87_RS24260 () | 13549..14919 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| GUU87_RS24265 () | 15393..15587 | + | 195 | Protein_12 | IS200-IS605 family transposase IS200C | Transposase |
| GUU87_RS24270 () | 15716..16657 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| GUU87_RS24275 () | 16892..18281 | - | 1390 | Protein_14 | ISNCY family transposase ISKpn21 | Transposase |
| GUU87_RS24280 () | 18591..18740 | - | 150 | Protein_15 | IS3 family transposase IS2 | Transposase |
| GUU87_RS24285 () | 18918..20111 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| GUU87_RS24290 () | 21334..22570 | - | 1237 | Protein_17 | IS3 family transposase IS2 | Transposase |
| GUU87_RS24295 () | 23197..23490 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| GUU87_RS24300 () | 23548..23747 | - | 200 | Protein_19 | lysis protein | - |
| GUU87_RS24305 () | 24301..25401 | + | 1101 | Protein_20 | IS481 family transposase ISKpn28 | Transposase |
| GUU87_RS24310 () | 26637..27752 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| GUU87_RS24315 () | 27892..31551 | + | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| GUU87_RS24320 () | 31655..32884 | + | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| GUU87_RS24325 () | 32969..33925 | + | 957 | WP_064055648.1 | Ferri-bacillibactin esterase BesA | VF |
| GUU87_RS24330 () | 33970..36147 | - | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| GUU87_RS24335 () | 36382..37079 | + | 698 | Protein_26 | IS1 family transposase | - |
| GUU87_RS24340 () | 37090..37293 | - | 204 | WP_001259759.1 | colicin V family bacteriocin | - |
| GUU87_RS24345 () | 37271..37507 | - | 237 | WP_014640552.1 | colicin V immunity protein | - |
| GUU87_RS24350 () | 37971..38252 | - | 282 | WP_001105066.1 | hypothetical protein | - |
| GUU87_RS24355 () | 38425..38592 | + | 168 | Protein_30 | colicin-B | - |
| GUU87_RS24360 () | 38610..39137 | - | 528 | WP_000203272.1 | colicin B immunity protein | - |
| GUU87_RS24365 () | 39381..40196 | + | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| GUU87_RS24370 () | 40246..40599 | - | 354 | WP_000864812.1 | colicin M immunity protein | - |
| GUU87_RS24375 () | 40777..41568 | - | 792 | WP_000016493.1 | site-specific integrase | - |
| GUU87_RS24380 () | 41565..42254 | - | 690 | WP_000796228.1 | hypothetical protein | - |
| GUU87_RS24385 () | 42298..42648 | - | 351 | WP_000493379.1 | hypothetical protein | - |
| GUU87_RS24390 () | 43180..47001 | - | 3822 | WP_064055658.1 | hypothetical protein | - |
| GUU87_RS25125 () | 47245..47406 | + | 162 | WP_000251882.1 | hypothetical protein | - |
| GUU87_RS24395 () | 47424..47771 | - | 348 | WP_000142450.1 | hypothetical protein | - |
| GUU87_RS24400 () | 48073..48555 | - | 483 | WP_001311056.1 | hypothetical protein | - |
| GUU87_RS24405 () | 48672..49520 | - | 849 | WP_023154360.1 | 3'-5' exonuclease | - |
| GUU87_RS24410 () | 49566..49847 | - | 282 | WP_000969990.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| GUU87_RS24415 () | 49844..49921 | - | 78 | Protein_43 | toxin-antitoxin system protein | - |
| GUU87_RS24420 () | 49954..50670 | - | 717 | Protein_44 | Tn3 family transposase | - |
| GUU87_RS24425 () | 50704..53709 | - | 3006 | WP_001143760.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| GUU87_RS24430 () | 53873..54430 | + | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| GUU87_RS24435 () | 54613..55473 | + | 861 | WP_015058868.1 | Beta-lactamase TEM | ARG |
| GUU87_RS24440 () | 55621..55968 | - | 348 | Protein_48 | IS6 family transposase IS15DII | Transposase |
| GUU87_RS24445 () | 56215..56688 | - | 474 | WP_004201280.1 | Dihydrofolate reductase type 1 | ARG |
| GUU87_RS24450 () | 56844..57848 | + | 1005 | Protein_50 | IS91 family transposase ISAzo26 | Transposase |
| GUU87_RS24455 () | 57902..58606 | - | 705 | WP_086525284.1 | IS6 family transposase IS26 | Transposase |
| GUU87_RS24460 () | 58673..59289 | - | 617 | Protein_52 | transposase | - |
| GUU87_RS24465 () | 59684..60340 | + | 657 | WP_001516695.1 | Pentapeptide repeat protein | ARG |
| GUU87_RS24470 () | 60659..61087 | - | 429 | Protein_54 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| GUU87_RS24475 () | 61120..62511 | - | 1392 | WP_001493761.1 | ISKra4 family transposase ISKpn19 | Transposase |
| GUU87_RS24480 () | 62548..63120 | - | 573 | WP_001493762.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| GUU87_RS24485 () | 63257..63847 | - | 591 | WP_012477564.1 | plasmid pRiA4b ORF-3 family protein | - |
| GUU87_RS24490 () | 63965..64207 | + | 243 | WP_000844627.1 | transposase | - |
| GUU87_RS24495 () | 64239..64889 | - | 651 | WP_159186494.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| GUU87_RS24500 () | 64995..66194 | + | 1200 | WP_032153701.1 | tetracycline efflux MFS transporter Tet(A) | - |
| GUU87_RS24505 () | 66161..66349 | - | 189 | Protein_61 | IS91 family transposase | - |
| GUU87_RS24510 () | 66461..66766 | - | 306 | WP_001255015.1 | HTH-type transcriptional regulator CynR | VF |
| GUU87_RS24515 () | 66794..68008 | - | 1215 | WP_000214121.1 | Bicyclomycin resistance protein | ARG |
| GUU87_RS25130 () | 68225..68671 | - | 447 | Protein_64 | DUF3363 domain-containing protein | - |
| GUU87_RS24525 () | 69140..70633 | - | 1494 | WP_001120888.1 | IS91 family transposase ISVsa3 | Transposase |
| GUU87_RS24530 () | 70844..71068 | - | 225 | WP_000743213.1 | hypothetical protein | - |
| GUU87_RS24535 () | 71065..71802 | - | 738 | WP_001366550.1 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| GUU87_RS24540 () | 72288..72428 | - | 141 | WP_001044210.1 | hypothetical protein | - |
| GUU87_RS24545 () | 72434..73138 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| GUU87_RS24550 () | 73261..73662 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| GUU87_RS24555 () | 73595..73852 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| GUU87_RS24560 () | 73945..74598 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| GUU87_RS24565 () | 75538..76395 | - | 858 | WP_000130940.1 | incFII family plasmid replication initiator RepA | - |
| GUU87_RS24570 () | 76388..76462 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| GUU87_RS24575 () | 76688..76948 | - | 261 | WP_000083818.1 | replication regulatory protein RepA | - |
| GUU87_RS24580 () | 77187..77760 | - | 574 | Protein_76 | DUF2726 domain-containing protein | - |
| GUU87_RS24585 () | 77798..78007 | - | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| GUU87_RS24590 () | 78053..78514 | - | 462 | WP_001233871.1 | thermonuclease family protein | - |
| GUU87_RS24595 () | 78757..78969 | - | 213 | WP_012311405.1 | hypothetical protein | - |
| GUU87_RS24600 () | 79107..79667 | - | 561 | WP_000139359.1 | fertility inhibition protein FinO | - |
| GUU87_RS24605 () | 79722..80468 | - | 747 | WP_000205777.1 | conjugal transfer pilus acetylase TraX | - |
| GUU87_RS24610 () | 80488..85758 | - | 5271 | WP_072769080.1 | Multifunctional conjugation protein TraI | Relaxase |
| GUU87_RS24615 () | 85758..88001 | - | 2244 | WP_104211547.1 | type IV conjugative transfer system coupling protein TraD | - |
| GUU87_RS24620 () | 88254..88985 | - | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| GUU87_RS24625 () | 89017..89520 | - | 504 | WP_000605510.1 | hypothetical protein | - |
| GUU87_RS24630 () | 89535..92357 | - | 2823 | WP_001007026.1 | conjugal transfer mating pair stabilization protein TraG | - |
| GUU87_RS24635 () | 92354..93727 | - | 1374 | WP_001137358.1 | conjugal transfer protein TraH | - |
| GUU87_RS24640 () | 93727..94089 | - | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| GUU87_RS24645 () | 94019..94564 | - | 546 | WP_000052618.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| GUU87_RS24650 () | 94551..94835 | - | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| GUU87_RS24655 () | 94954..95301 | - | 348 | WP_001287893.1 | conjugal transfer protein TrbA | - |
| GUU87_RS24660 () | 95317..96060 | - | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| GUU87_RS24665 () | 96053..96310 | - | 258 | WP_000864325.1 | conjugal transfer protein TrbE | - |
| GUU87_RS24670 () | 96337..98145 | - | 1809 | WP_000821821.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| GUU87_RS24675 () | 98142..98780 | - | 639 | WP_001104248.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| GUU87_RS24680 () | 98808..99134 | - | 327 | Protein_96 | hypothetical protein | - |
| GUU87_RS24690 () | 100418..100573 | - | 156 | WP_160183924.1 | hypothetical protein | - |
| GUU87_RS24695 () | 100603..101064 | - | 462 | WP_000277845.1 | hypothetical protein | - |
| GUU87_RS24700 () | 101090..102082 | - | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| GUU87_RS24705 () | 102079..102711 | - | 633 | WP_001203745.1 | type-F conjugative transfer system protein TraW | - |
| GUU87_RS24710 () | 102708..103094 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| GUU87_RS24715 () | 103091..105718 | - | 2628 | WP_001064268.1 | type IV secretion system protein TraC | - |
| GUU87_RS24720 () | 105878..106099 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| GUU87_RS24725 () | 106234..106749 | - | 516 | WP_000809906.1 | type IV conjugative transfer system lipoprotein TraV | - |
| GUU87_RS24730 () | 106746..106997 | - | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| GUU87_RS24735 () | 106994..107311 | - | 318 | WP_001057292.1 | conjugal transfer protein TrbD | - |
| GUU87_RS24740 () | 107308..107880 | - | 573 | WP_000002780.1 | conjugal transfer protein TraP | - |
| GUU87_RS24745 () | 107870..109297 | - | 1428 | Protein_109 | conjugal transfer protein TraB | - |
| GUU87_RS24750 () | 109297..110001 | - | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| GUU87_RS24755 () | 110012..110578 | - | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| GUU87_RS24760 () | 110600..110911 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| GUU87_RS24765 () | 110926..111285 | - | 360 | WP_000340272.1 | type IV conjugative transfer system pilin TraA | - |
| GUU87_RS24770 () | 111319..111546 | - | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| GUU87_RS24775 () | 111640..112326 | - | 687 | WP_000332484.1 | PAS domain-containing protein | - |
| GUU87_RS24780 () | 112517..112900 | - | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| GUU87_RS24785 () | 113177..113824 | + | 648 | WP_000614936.1 | hypothetical protein | VF |
| GUU87_RS24790 () | 114121..114942 | - | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| GUU87_RS24795 () | 115064..115351 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| GUU87_RS25135 () | 115376..115582 | - | 207 | WP_000547939.1 | hypothetical protein | - |
| GUU87_RS24805 () | 116273..116431 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 116475..116699 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 116475..116699 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 116475..116699 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 116475..116699 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| GUU87_RS24810 () | 116511..116699 | + | 189 | WP_001299721.1 | hypothetical protein | - |
| GUU87_RS24815 () | 116711..117430 | - | 720 | WP_001276228.1 | plasmid SOS inhibition protein A | - |
| GUU87_RS24820 () | 117427..117861 | - | 435 | WP_000845895.1 | conjugation system SOS inhibitor PsiB | - |
| GUU87_RS24825 () | 117916..119874 | - | 1959 | WP_001145469.1 | ParB/RepB/Spo0J family partition protein | - |
| GUU87_RS24830 () | 119933..120166 | - | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| GUU87_RS24835 () | 120222..120749 | - | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| GUU87_RS24845 () | 121222..121494 | - | 273 | WP_072133095.1 | hypothetical protein | - |
| GUU87_RS24850 () | 121646..122209 | - | 564 | WP_001311069.1 | class I SAM-dependent methyltransferase | - |
| GUU87_RS24855 () | 122255..123616 | - | 1362 | WP_000170681.1 | DUF3560 domain-containing protein | - |
| GUU87_RS24860 () | 123668..123898 | - | 231 | WP_000218642.1 | hypothetical protein | - |
| GUU87_RS25140 () | 124576..124904 | + | 329 | Protein_132 | pilus assembly protein | - |
| GUU87_RS24870 () | 124892..125074 | - | 183 | WP_001027505.1 | hypothetical protein | - |
| GUU87_RS24875 () | 125074..125535 | - | 462 | WP_042007484.1 | DUF1380 family protein | - |
| GUU87_RS24880 () | 125535..125837 | - | 303 | WP_072256028.1 | antirestriction protein | - |
| GUU87_RS24890 () | 126362..127333 | + | 972 | WP_000082154.1 | IS110 family transposase ISEc32 | Transposase |
| GUU87_RS24895 () | 127386..128083 | - | 698 | Protein_137 | IS1 family transposase | - |
| GUU87_RS24900 () | 128137..128469 | - | 333 | Protein_138 | hypothetical protein | - |
| GUU87_RS25145 () | 128538..128876 | - | 339 | WP_001513511.1 | hypothetical protein | - |
| GUU87_RS24915 () | 129688..130659 | - | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| GUU87_RS24920 () | 130659..131825 | - | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| GUU87_RS24925 () | 132125..132822 | - | 698 | Protein_142 | IS1 family transposase | - |
| GUU87_RS24930 () | 132878..133117 | - | 240 | Protein_143 | IS21 family transposase IS21 | Transposase |
| GUU87_RS24935 () | 133366..134579 | + | 1214 | WP_085947772.1 | IS3 family transposase ISCfr6 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|