NZ_CP0466461..162487

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 162487 bp
Accession: NZ_CP046646        Location: 1..162487         Organism: Klebsiella pneumoniae strain EGKP3       Replicon: plasmid pEGKP3.1-2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GPU01_RS25740 (GPU01_25390) 1..1011 + 1011 WP_000200070.1 RepB family plasmid replication initiator protein -
GPU01_RS25745 (GPU01_25395) 1728..2468 - 741 WP_001515717.1 tyrosine-type recombinase/integrase -
GPU01_RS25750 (GPU01_25400) 3612..4559 + 948 WP_032439675.1 sensor domain-containing diguanylate cyclase -
GPU01_RS25755 (GPU01_25405) 4586..5332 - 747 WP_071557569.1 putative signaling protein VF
GPU01_RS25765 (GPU01_25415) 6835..7092 - 258 WP_023292103.1 hypothetical protein -
GPU01_RS25770 7570..8298 + 729 Protein_6 putative cyclic di-GMP phosphodiesterase PdeB VF
GPU01_RS25775 8314..9150 + 837 WP_032439674.1 putative cyclic di-GMP phosphodiesterase PdeB VF
GPU01_RS25780 (GPU01_25425) 9768..10199 - 432 WP_174805835.1 hypothetical protein -
GPU01_RS25785 10741..11163 - 423 WP_046624301.1 hypothetical protein -
GPU01_RS25790 (GPU01_25430) 11120..11350 + 231 WP_001261282.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
GPU01_RS25795 (GPU01_25435) 11347..11763 + 417 WP_016236302.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
GPU01_RS25800 (GPU01_25440) 11837..13399 + 1563 WP_004206609.1 AAA family ATPase -
GPU01_RS25805 (GPU01_25445) 13384..14406 + 1023 WP_032439672.1 helicase UvrD -
GPU01_RS25810 (GPU01_25450) 14951..15859 + 909 WP_117254255.1 HNH endonuclease signature motif containing protein -
GPU01_RS25815 (GPU01_25455) 16045..16395 - 351 WP_004187110.1 DUF305 domain-containing protein -
GPU01_RS25820 (GPU01_25460) 16543..16974 - 432 WP_032413339.1 silver-binding protein SilE -
GPU01_RS25825 (GPU01_25465) 17219..18700 - 1482 WP_032439671.1 copper/silver sensor histidine kinase SilS -
GPU01_RS25830 (GPU01_25470) 18693..19373 - 681 WP_004118020.1 Transcriptional regulatory protein CusR VF
GPU01_RS25835 (GPU01_25475) 19563..20948 + 1386 WP_032439669.1 Cation efflux system protein CusC VF
GPU01_RS25840 (GPU01_25480) 20978..21331 + 354 WP_032439668.1 cation efflux system protein CusF -
GPU01_RS25845 (GPU01_25485) 21445..22737 + 1293 WP_001548143.1 Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB -
GPU01_RS25850 (GPU01_25490) 22748..25894 + 3147 WP_032439667.1 Cu(+)/Ag(+) efflux RND transporter permease subunit SilA -
GPU01_RS25855 (GPU01_25495) 25981..26421 + 441 WP_002436620.1 DUF411 domain-containing protein -
GPU01_RS25860 (GPU01_25500) 26519..28990 + 2472 WP_128337628.1 Ag(+)-translocating P-type ATPase SilP -
GPU01_RS25865 (GPU01_25505) 29031..29228 + 198 WP_000843497.1 DUF2933 domain-containing protein -
GPU01_RS25870 (GPU01_25510) 29262..29999 - 738 WP_000287501.1 Murein DD-endopeptidase MepM VF
GPU01_RS25875 (GPU01_25515) 30288..30737 - 450 WP_001023257.1 copper resistance protein -
GPU01_RS25880 (GPU01_25520) 30898..31929 - 1032 WP_071905678.1 IS630 family transposase ISSpu2 Transposase
GPU01_RS25885 (GPU01_25525) 32126..33943 + 1818 WP_000925242.1 multicopper oxidase PcoA -
GPU01_RS25890 (GPU01_25530) 33949..34839 + 891 WP_001378118.1 copper resistance outer membrane transporter PcoB -
GPU01_RS25895 (GPU01_25535) 34879..35259 + 381 WP_000025662.1 copper resistance system metallochaperone PcoC -
GPU01_RS25900 (GPU01_25540) 35264..36193 + 930 WP_004118344.1 copper resistance inner membrane protein PcoD -
GPU01_RS25905 (GPU01_25545) 36248..36928 + 681 WP_001188930.1 Transcriptional activator protein CopR VF
GPU01_RS25910 (GPU01_25550) 36925..38325 + 1401 WP_002436614.1 copper resistance membrane spanning protein PcoS -
GPU01_RS25915 (GPU01_25555) 38541..38975 + 435 WP_004118347.1 hypothetical protein -
GPU01_RS25920 39155..39317 - 163 Protein_36 type II toxin-antitoxin system RelE/ParE family toxin -
GPU01_RS25925 (GPU01_25565) 39439..39618 - 180 WP_004118349.1 type II toxin-antitoxin system ParD family antitoxin -
GPU01_RS25930 (GPU01_25570) 39932..40195 + 264 WP_009310051.1 hypothetical protein -
GPU01_RS25935 (GPU01_25575) 40192..40758 + 567 WP_032439665.1 hypothetical protein -
GPU01_RS25940 (GPU01_25580) 40789..41283 + 495 WP_004213594.1 hypothetical protein -
GPU01_RS25945 (GPU01_25585) 41344..41547 + 204 WP_004150739.1 HHA domain-containing protein -
GPU01_RS25950 (GPU01_25590) 41655..42624 + 970 Protein_42 IS5 family transposase IS903B Transposase
GPU01_RS25955 (GPU01_25595) 42729..44096 - 1368 WP_023329010.1 formimidoylglutamate deiminase -
GPU01_RS25960 (GPU01_25600) 44199..44960 + 762 WP_032439663.1 histidine utilization repressor -
GPU01_RS25965 (GPU01_25605) 44957..45514 + 558 WP_032439662.1 HutD family protein -
GPU01_RS25970 (GPU01_25610) 45548..47080 - 1533 WP_032439660.1 aromatic amino acid ammonia-lyase -
GPU01_RS25975 (GPU01_25615) 47091..47966 - 876 WP_032439658.1 ABC transporter substrate-binding protein -
GPU01_RS25980 (GPU01_25620) 47997..48677 - 681 WP_032439656.1 ABC transporter permease -
GPU01_RS25985 (GPU01_25625) 48680..49324 - 645 WP_032439654.1 ABC transporter permease subunit -
GPU01_RS25990 (GPU01_25630) 49321..50418 - 1098 WP_064184845.1 Osmoprotectant import ATP-binding protein OsmV VF
GPU01_RS25995 (GPU01_25635) 50926..52602 + 1677 WP_014228068.1 urocanate hydratase -
GPU01_RS26000 (GPU01_25640) 52655..54049 + 1395 WP_032439652.1 cytosine permease -
GPU01_RS26005 (GPU01_25645) 54061..55269 + 1209 WP_032439650.1 imidazolonepropionase -
GPU01_RS26010 (GPU01_25650) 55262..56071 + 810 WP_023329017.1 N-formylglutamate deformylase -
GPU01_RS26015 (GPU01_25655) 57183..57449 + 267 WP_003026799.1 DUF1778 domain-containing protein Antitoxin Detail
GPU01_RS26020 (GPU01_25660) 57437..57919 + 483 WP_004187044.1 GNAT family N-acetyltransferase Toxin Detail
GPU01_RS26025 (GPU01_25665) 58126..59472 + 1347 WP_077254728.1 ISNCY family transposase ISLad2 Transposase
GPU01_RS26030 (GPU01_25670) 59521..59919 + 399 WP_032422684.1 ISNCY family transposase ISKpn21 Transposase
GPU01_RS26035 60067..60177 - 111 Protein_59 IS3 family transposase ISKpn38 Transposase
GPU01_RS26040 (GPU01_25680) 60452..61388 + 937 Protein_60 ISNCY family transposase -
GPU01_RS26045 (GPU01_25685) 62436..63713 - 1278 WP_032439648.1 DUF2254 domain-containing protein -
GPU01_RS26050 (GPU01_25690) 63776..65773 - 1998 WP_023307506.1 choline BCCT transporter BetT -
GPU01_RS26055 (GPU01_25695) 66202..66591 - 390 Protein_63 LysR family transcriptional regulator -
GPU01_RS26060 (GPU01_25700) 67380..67733 + 354 WP_001114073.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
GPU01_RS26065 (GPU01_25705) 67781..68143 + 363 WP_004118102.1 arsenite efflux transporter metallochaperone ArsD -
GPU01_RS26070 (GPU01_25710) 68161..69912 + 1752 WP_019704517.1 arsenite efflux transporter ATPase subunit ArsA -
GPU01_RS26075 (GPU01_25715) 69960..71236 + 1277 Protein_67 arsenite efflux transporter membrane subunit ArsB -
GPU01_RS26080 (GPU01_25720) 71249..71674 + 426 WP_032439646.1 glutaredoxin-dependent arsenate reductase -
GPU01_RS26085 (GPU01_25730) 71911..72639 + 729 WP_023307503.1 hypothetical protein -
GPU01_RS26090 72699..72827 + 129 Protein_70 transcriptional regulator -
GPU01_RS26095 (GPU01_25735) 72895..73860 - 966 WP_004118146.1 DMT family transporter -
GPU01_RS26100 (GPU01_25740) 73857..74675 - 819 WP_004206594.1 Glutamine transport ATP-binding protein GlnQ VF
GPU01_RS26105 (GPU01_25745) 74680..75342 - 663 WP_032439643.1 amino acid ABC transporter permease -
GPU01_RS26110 (GPU01_25750) 75339..76010 - 672 WP_032439641.1 amino acid ABC transporter permease -
GPU01_RS26115 (GPU01_25755) 76034..76882 - 849 WP_032439640.1 transporter substrate-binding domain-containing protein -
GPU01_RS26120 (GPU01_25760) 77038..77991 + 954 WP_032439639.1 Glycine cleavage system transcriptional activator VF
GPU01_RS26125 (GPU01_25765) 78078..79295 + 1218 WP_032439636.1 aminopeptidase P family protein -
GPU01_RS26130 (GPU01_25770) 79334..79453 + 120 Protein_78 IS21 family transposase -
GPU01_RS26135 79723..79792 - 70 Protein_79 hypothetical protein -
GPU01_RS26140 (GPU01_25775) 79929..80450 + 522 WP_032439635.1 putative RNA polymerase sigma factor FecI VF
GPU01_RS26145 (GPU01_25780) 80447..81400 + 954 WP_030003506.1 ferric citrate uptake sigma factor regulator FecR -
GPU01_RS26150 (GPU01_25785) 81487..83805 + 2319 WP_032448287.1 TonB-dependent Fe(3+) dicitrate receptor FecA -
GPU01_RS26155 (GPU01_25790) 83850..84752 + 903 WP_004182127.1 Fe(3+) dicitrate ABC transporter substrate-binding protein FecB -
GPU01_RS26160 (GPU01_25795) 84749..85747 + 999 WP_004182126.1 Fe(3+) dicitrate transport system permease protein FecC VF
GPU01_RS26165 (GPU01_25800) 85744..86700 + 957 WP_004118246.1 Fe(3+) dicitrate transport system permease protein FecD VF
GPU01_RS26170 (GPU01_25805) 86701..87468 + 768 WP_004152282.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
GPU01_RS26175 (GPU01_25810) 87567..87860 + 294 WP_004118251.1 IS66 family transposase ISKpn24 Transposase
GPU01_RS26180 (GPU01_25815) 87935..88162 + 228 Protein_88 IS66 family transposase -
GPU01_RS26185 (GPU01_25820) 88191..88433 - 243 WP_071527925.1 EAL domain-containing protein -
GPU01_RS26190 (GPU01_25825) 88812..89822 - 1011 WP_004152284.1 zinc-binding alcohol dehydrogenase family protein -
GPU01_RS26195 90165..90247 + 83 Protein_91 hypothetical protein -
GPU01_RS26200 (GPU01_25830) 90283..91365 + 1083 WP_016831235.1 DNA-binding transcriptional repressor LacI -
GPU01_RS26205 (GPU01_25835) 91487..94561 + 3075 WP_040149081.1 beta-galactosidase -
GPU01_RS26210 (GPU01_25840) 94613..95866 + 1254 WP_032439628.1 lactose permease -
GPU01_RS26215 (GPU01_25845) 95932..96072 + 141 Protein_95 galactoside O-acetyltransferase -
GPU01_RS26220 (GPU01_25850) 96087..96783 - 697 Protein_96 IS1 family transposase -
GPU01_RS26225 (GPU01_25855) 96972..97232 - 261 WP_023313931.1 DUF2534 family protein -
GPU01_RS26230 (GPU01_25860) 97289..99352 - 2064 WP_032448285.1 TonB-dependent copper receptor -
GPU01_RS26235 (GPU01_25865) 99435..99854 - 420 WP_015065566.1 DUF2946 domain-containing protein -
GPU01_RS26240 (GPU01_25870) 100378..100692 - 315 WP_176700729.1 hypothetical protein -
GPU01_RS26245 (GPU01_25880) 100798..101921 + 1124 WP_265582912.1 IS3 family transposase ISEc15 Transposase
GPU01_RS26250 (GPU01_25885) 102307..102627 + 321 WP_004197483.1 hypothetical protein -
GPU01_RS26255 (GPU01_25890) 103991..104848 - 858 WP_004099067.1 incFII family plasmid replication initiator RepA -
GPU01_RS26260 (GPU01_25900) 105134..105412 - 279 WP_004099069.1 replication regulatory protein RepA -
GPU01_RS26265 (GPU01_25905) 105733..106284 - 552 WP_013213996.1 Phospholipase D VF
GPU01_RS26270 106389..106468 - 80 Protein_106 hypothetical protein -
GPU01_RS26275 (GPU01_25910) 106570..106771 - 202 Protein_107 bacteriocin immunity protein -
GPU01_RS26285 107556..107651 - 96 Protein_109 hypothetical protein -
GPU01_RS26290 (GPU01_25920) 107812..108405 - 594 WP_004152380.1 fertility inhibition protein FinO -
GPU01_RS26295 (GPU01_25925) 108477..109202 - 726 WP_014386207.1 type-F conjugative transfer system pilin acetylase TraX -
GPU01_RS26300 (GPU01_25930) 109247..114505 - 5259 WP_032448280.1 Multifunctional conjugation protein TraI Relaxase
GPU01_RS26305 (GPU01_25935) 114505..116817 - 2313 WP_013214038.1 type IV conjugative transfer system coupling protein TraD -
GPU01_RS26310 116944..117633 - 690 WP_014343485.1 hypothetical protein -
GPU01_RS26315 (GPU01_25945) 117826..118557 - 732 WP_013214036.1 conjugal transfer complement resistance protein TraT -
GPU01_RS26320 (GPU01_25950) 118808..119410 - 603 WP_013214035.1 conjugal transfer protein TraS -
GPU01_RS26325 (GPU01_25955) 119433..122255 - 2823 WP_265582913.1 conjugal transfer mating-pair stabilization protein TraG -
GPU01_RS26330 (GPU01_25960) 122255..123634 - 1380 WP_074160414.1 conjugal transfer pilus assembly protein TraH -
GPU01_RS26335 (GPU01_25965) 123612..124055 - 444 WP_013214032.1 F-type conjugal transfer protein TrbF -
GPU01_RS26340 (GPU01_25970) 124101..124658 - 558 WP_013214031.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
GPU01_RS26345 (GPU01_25975) 124630..124869 - 240 WP_004144400.1 type-F conjugative transfer system pilin chaperone TraQ -
GPU01_RS26350 (GPU01_25980) 124880..125632 - 753 WP_004152677.1 type-F conjugative transfer system pilin assembly protein TraF -
GPU01_RS26355 (GPU01_25985) 125653..125979 - 327 WP_013214030.1 hypothetical protein -
GPU01_RS26360 (GPU01_25990) 125992..126240 - 249 WP_013214029.1 hypothetical protein -
GPU01_RS26365 (GPU01_25995) 126218..126472 - 255 WP_004152674.1 conjugal transfer protein TrbE -
GPU01_RS26370 (GPU01_26000) 126504..128459 - 1956 WP_032448279.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
GPU01_RS26375 (GPU01_26005) 128518..129165 - 648 WP_032439622.1 type-F conjugative transfer system pilin assembly protein TrbC -
GPU01_RS26380 129244..129420 - 177 WP_162866177.1 hypothetical protein -
GPU01_RS26385 (GPU01_26010) 129441..130430 - 990 WP_032439620.1 conjugal transfer pilus assembly protein TraU -
GPU01_RS26390 (GPU01_26015) 130427..130828 - 402 WP_016831047.1 hypothetical protein -
GPU01_RS26395 (GPU01_26020) 130863..131498 - 636 WP_020325113.1 type-F conjugative transfer system protein TraW -
GPU01_RS26400 (GPU01_26025) 131498..131887 - 390 WP_004167468.1 type-F conjugative transfer system protein TrbI -
GPU01_RS26405 (GPU01_26030) 131887..134526 - 2640 WP_032448278.1 type IV secretion system protein TraC -
GPU01_RS26410 (GPU01_26035) 134598..134996 - 399 WP_072159473.1 hypothetical protein -
GPU01_RS26415 (GPU01_26040) 135004..135393 - 390 WP_065799586.1 hypothetical protein -
GPU01_RS26420 (GPU01_26045) 135436..135840 - 405 WP_016831042.1 hypothetical protein -
GPU01_RS26425 (GPU01_26050) 135907..136218 - 312 WP_014386200.1 hypothetical protein -
GPU01_RS26430 (GPU01_26055) 136219..136437 - 219 WP_014386199.1 hypothetical protein -
GPU01_RS26435 (GPU01_26060) 136461..136751 - 291 WP_014386198.1 hypothetical protein -
GPU01_RS26440 (GPU01_26065) 136756..137166 - 411 WP_014386197.1 hypothetical protein -
GPU01_RS26445 (GPU01_26070) 137297..137881 - 585 WP_014386196.1 type IV conjugative transfer system lipoprotein TraV -
GPU01_RS26450 (GPU01_26075) 137928..138500 - 573 WP_014386195.1 conjugal transfer pilus-stabilizing protein TraP -
GPU01_RS26455 (GPU01_26080) 138493..139917 - 1425 WP_014386194.1 F-type conjugal transfer pilus assembly protein TraB -
GPU01_RS26460 (GPU01_26085) 139917..140657 - 741 WP_014386193.1 type-F conjugative transfer system secretin TraK -
GPU01_RS26465 (GPU01_26090) 140644..141210 - 567 WP_004152602.1 type IV conjugative transfer system protein TraE -
GPU01_RS26470 (GPU01_26095) 141230..141535 - 306 WP_004144424.1 type IV conjugative transfer system protein TraL -
GPU01_RS26475 (GPU01_26100) 141549..141917 - 369 WP_004194426.1 type IV conjugative transfer system pilin TraA -
GPU01_RS26480 (GPU01_26105) 141979..142185 - 207 WP_171773970.1 TraY domain-containing protein -
GPU01_RS26485 (GPU01_26110) 142318..143037 - 720 WP_014386192.1 conjugal transfer protein -
GPU01_RS26490 (GPU01_26115) 143230..143646 - 417 WP_072145360.1 conjugal transfer relaxosome DNA-binding protein TraM -
GPU01_RS26495 (GPU01_26120) 144037..144522 + 486 WP_004178063.1 hypothetical protein VF
GPU01_RS26500 (GPU01_26125) 144555..144884 - 330 WP_014386191.1 DUF5983 family protein -
GPU01_RS26505 (GPU01_26130) 144917..145738 - 822 WP_004182076.1 DUF932 domain-containing protein -
GPU01_RS26510 (GPU01_26135) 146571..146984 - 414 WP_013023817.1 helix-turn-helix domain-containing protein -
GPU01_RS26515 (GPU01_26140) 146985..147263 - 279 WP_004152721.1 helix-turn-helix transcriptional regulator -
GPU01_RS26520 (GPU01_26145) 147253..147573 - 321 WP_004152720.1 type II toxin-antitoxin system RelE/ParE family toxin -
GPU01_RS26525 (GPU01_26150) 147654..147878 - 225 WP_014386189.1 hypothetical protein -
GPU01_RS26530 (GPU01_26155) 147889..148101 - 213 WP_014386188.1 hypothetical protein -
GPU01_RS26535 (GPU01_26160) 148163..148489 - 327 WP_014386187.1 hypothetical protein -
GPU01_RS26540 (GPU01_26165) 149326..149889 - 564 WP_004152756.1 methyltransferase -
GPU01_RS26545 (GPU01_26170) 149937..151292 - 1356 WP_014386157.1 DUF3560 domain-containing protein -
GPU01_RS26550 (GPU01_26175) 151344..151574 - 231 WP_001568051.1 hypothetical protein -
GPU01_RS26555 (GPU01_26180) 151666..151893 - 228 WP_004178072.1 hypothetical protein -
GPU01_RS26560 (GPU01_26185) 152674..152991 - 318 WP_004118473.1 hypothetical protein -
GPU01_RS26565 (GPU01_26190) 153026..153280 - 255 WP_004152754.1 DNA polymerase III subunit theta -
GPU01_RS26570 (GPU01_26195) 153517..153942 - 426 WP_004118478.1 antirestriction protein -
GPU01_RS26575 (GPU01_26200) 154463..154693 - 231 WP_004118481.1 hypothetical protein -
GPU01_RS26580 (GPU01_26205) 154907..155332 + 426 WP_004182047.1 translesion error-prone DNA polymerase V autoproteolytic subunit -
GPU01_RS26585 (GPU01_26210) 155332..156603 + 1272 WP_014386156.1 Y-family DNA polymerase -
GPU01_RS26590 (GPU01_26215) 156742..156897 + 156 WP_001776126.1 hypothetical protein -
GPU01_RS26595 (GPU01_26220) 156920..158118 - 1199 Protein_171 IS200-IS605 family transposase IS609 Transposase
GPU01_RS26600 (GPU01_26225) 159599..160570 - 972 WP_004152062.1 ParB/RepB/Spo0J family plasmid partition protein -
GPU01_RS26605 (GPU01_26230) 160570..161736 - 1167 WP_000523813.1 Sporulation initiation inhibitor protein Soj VF

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance